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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal somite development
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Accession:MP:0001688 term browser browse the term
Definition:any anomaly in the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo; somites are transient structures - balls or blocks of paraxial mesoderm cells with an epithelial outer layer and a mesenchymal cell core - that emerge sequentially through a mesenchymal-to-epithelial transition (MET) from the morphologically unpatterned presomitic mesoderm; they give rise to the metameric anatomy of the vertebral column itself, and the associated skin, muscle and tendons
Synonyms:exact_synonym: abnormal metablastic segment development;   abnormal somite formation;   abnormal somite segmentation;   abnormal somitogenesis



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abnormal somite development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S F344-Oune/Kyo Oune IMP compared to F344 RGD PMID:26090680 RGD:10045933

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  mammalian phenotype 5370
    embryo phenotype 6
      abnormal embryo morphology 2
        abnormal embryonic tissue morphology 1
          abnormal somite development 1
            abnormal dorsal-ventral polarity of the somites 0
            abnormal left-right axis symmetry of the somites 0
            abnormal rostral-caudal patterning of the somites 0
            abnormal somite border morphology 0
            abnormal somite segmentation clock + 0
            abnormal somite shape 0
            abnormal somite size + 0
            delayed somite formation 0
            fused somites 0
            impaired somite development + 0
            increased somite number 0
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