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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal circulating alanine transaminase level
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Accession:MP:0001573 term browser browse the term
Definition:aberrant concentration in the blood of the enzyme which transfers amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction
Synonyms:exact_synonym: abnormal ALT level;   abnormal GPT level;   abnormal alanine aminotransferase level;   abnormal alanine transaminase level
 narrow_synonym: abnormal SGPT level;   abnormal serum glutamate pyruvate transaminase level;   abnormal serum glutamic-pyruvic transaminase level
 alt_id: MP:0000204



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decreased circulating alanine transaminase level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:30249809 RGD:41404725 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf1rtm(EGFP)Tset colony stimulating factor 1 receptor; target mutant, Tset IMP RGD PMID:30249809 RGD:41404725
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:23799078 RGD:13462048 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:23799078 RGD:13462048
increased circulating alanine transaminase level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7b ATPase copper transporting beta IAGP compared to LEA/Hok RGD PMID:30733544 PMID:17303181 RGD:25823141, RGD:2292672 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atp7bhts ATPase copper transporting beta; hepatitis IAGP compared to LEA/Hok RGD PMID:17303181 PMID:30733544 RGD:2292672, RGD:25823141
G Lepr leptin receptor IMP
IAGP
RGD PMID:27225180 PMID:23154293 RGD:12910507, RGD:13432147 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Leprem3 leptin receptor; TALEN induced mutant 3 IMP RGD PMID:27225180 RGD:12910507
G Leprfa leptin receptor; fa mutant IAGP RGD PMID:23154293 RGD:13432147
G P2ry2 purinergic receptor P2Y2 IMP RGD PMID:19155635 RGD:2316657 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G Ren renin IMP compared to wild type RGD PMID:21242461 RGD:7771614 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to wild type RGD PMID:21242461 RGD:7771614

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5400
    homeostasis/metabolism phenotype 1415
      abnormal homeostasis 1316
        abnormal enzyme/coenzyme level 83
          abnormal circulating enzyme level 60
            abnormal circulating alanine transaminase level 26
              decreased circulating alanine transaminase level 10
              increased circulating alanine transaminase level 15
Path 2
Term Annotations click to browse term
  mammalian phenotype 5400
    homeostasis/metabolism phenotype 1415
      abnormal homeostasis 1316
        abnormal protein level 134
          abnormal circulating protein level 106
            abnormal circulating enzyme level 60
              abnormal circulating alanine transaminase level 26
                decreased circulating alanine transaminase level 10
                increased circulating alanine transaminase level 15
paths to the root