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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

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Accession:MP:0001242 term browser browse the term
Definition:thickening of the horny layer of the epidermis
Synonyms:exact_synonym: epidermal hyperkeratosis;   thickened cornified layer;   thickened horny layer;   thickened stratum corneum;   thicker cornified layer;   thicker horny layer;   thicker stratum corneum
 alt_id: MP:0001223

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hyperkeratosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsg4 desmoglein 4 IAGP DNA:missense mutation:exon 8 (rat) RGD PMID:15617564 RGD:150521562 NCBI chr18:11,720,844...11,757,927
Ensembl chr18:11,720,975...11,756,234
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Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    integument phenotype 171
      abnormal skin morphology 16
        abnormal epidermal layer morphology 2
          abnormal epidermis stratum corneum morphology 2
            hyperkeratosis 2
              orthokeratosis 0
              parakeratosis 0
paths to the root