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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:abnormal epidermis stratum corneum morphology
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Accession:MP:0001240 term browser browse the term
Definition:any structural anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells
Synonyms:exact_synonym: abnormal cornified layer morphology;   abnormal horny layer morphology;   abnormal stratum corneum morphology;   cornified layer dysplasia;   epidermis stratum corneum dysplasia

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hyperkeratosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsg4 desmoglein 4 IAGP DNA:missense mutation:exon 8 (rat) RGD PMID:15617564 RGD:150521562 NCBI chr18:11,720,844...11,757,927
Ensembl chr18:11,720,975...11,756,234
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  mammalian phenotype 5417
    integument phenotype 171
      abnormal skin morphology 16
        abnormal epidermal layer morphology 2
          abnormal epidermis stratum corneum morphology 2
            abnormal corneocyte morphology + 0
            abnormal stratum corneum lipid matrix formation 0
            absent epidermis stratum corneum 0
            hyperkeratosis + 2
            impaired stratum corneum desquamation 0
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