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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:abnormal epidermal layer morphology
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Accession:MP:0001216 term browser browse the term
Definition:any structural anomaly of the superficial epithelial portion of the skin
Synonyms:exact_synonym: abnormal epidermis morphology;   epidermal dysplasia;   epidermal layer dysplasia
 alt_id: MP:0001225

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hyperkeratosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsg4 desmoglein 4 IAGP DNA:missense mutation:exon 8 (rat) RGD PMID:15617564 RGD:150521562 NCBI chr18:11,720,975...11,756,234
Ensembl chr18:11,720,975...11,756,234
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Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5373
    integument phenotype 168
      abnormal skin morphology 16
        abnormal epidermal layer morphology 2
          abnormal epidermal immune compartment + 0
          abnormal epidermis stratum basale morphology + 0
          abnormal epidermis stratum corneum morphology + 2
          abnormal epidermis stratum granulosum morphology + 0
          abnormal epidermis stratum lucidum morphology 0
          abnormal epidermis stratum spinosum morphology + 0
          abnormal epidermis suprabasal layer morphology + 0
          abnormal keratinocyte morphology + 0
          absent epidermis 0
          epidermal atrophy 0
          epidermal cyst 0
          epidermal desquamation 0
          epidermal hyperplasia 0
          epidermal necrosis 0
          thick epidermis 0
          thin epidermis 0
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