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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:optic nerve atrophy
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Accession:MP:0001059 term browser browse the term
Definition:acquired diminution of the size of the optic nerve, associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes
Synonyms:exact_synonym: Optic atrophy;   atrophic optic nerve;   atrophy of optic nerve
 alt_id: MP:0001331
 xref: HP:0000648


show annotations for term's descendants           Sort by:
optic nerve atrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbs4 Bardet-Biedl syndrome 4 IAGP MGI PMID:16794820 NCBI chr 9:59,229,249...59,260,791
Ensembl chr 9:59,229,273...59,260,791 		JBrowse link
G Elp1 elongator complex protein 1 IAGP MGI PMID:22922231 NCBI chr 4:56,746,547...56,802,565
Ensembl chr 4:56,749,680...56,802,331 		JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb IAGP MGI PMID:10192392 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863 		JBrowse link
G H2az2 H2A.Z histone variant 2 IAGP MGI PMID:27483349 NCBI chr11:6,377,226...6,394,511
Ensembl chr11:6,377,229...6,394,443 		JBrowse link
G Mettl23 methyltransferase like 23 IAGP MGI PMID:36099048 NCBI chr11:116,734,341...116,740,566
Ensembl chr11:116,734,104...116,745,089 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IAGP MGI PMID:27681422 NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 IAGP MGI PMID:20534480 NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794 		JBrowse link
G Pou4f2 POU domain, class 4, transcription factor 2 IAGP MGI PMID:19109949 NCBI chr 8:79,159,638...79,163,276
Ensembl chr 8:79,159,639...79,163,274 		JBrowse link
G Prss56 serine protease 56 IAGP MGI PMID:21532570 NCBI chr 1:87,111,002...87,116,127
Ensembl chr 1:87,111,035...87,116,127 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:21576358 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IAGP MGI PMID:21576358 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Rpl24 ribosomal protein L24 IAGP MGI PMID:8589526 NCBI chr16:55,786,638...55,791,800
Ensembl chr16:55,786,638...55,791,798 		JBrowse link
G Rybp RING1 and YY1 binding protein IAGP MGI PMID:17470285 NCBI chr 6:100,205,526...100,264,319
Ensembl chr 6:100,205,526...100,264,446 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B IAGP MGI PMID:21282566 NCBI chr11:32,297,777...32,378,189
Ensembl chr11:32,297,820...32,378,173 		JBrowse link
G Slc25a46 solute carrier family 25, member 46 IAGP MGI PMID:28376086 NCBI chr18:31,713,217...31,743,585
Ensembl chr18:31,689,164...31,742,964 		JBrowse link
G Taco1 translational activator of mitochondrially encoded cytochrome c oxidase I IAGP MGI PMID:27319982 NCBI chr11:105,956,885...105,964,861
Ensembl chr11:105,956,887...105,964,438 		JBrowse link
G Tfap2b transcription factor AP-2 beta IAGP MGI PMID:27483349 NCBI chr 1:19,279,132...19,309,071
Ensembl chr 1:19,279,138...19,308,800 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 IAGP MGI PMID:10192392 NCBI chr 4:80,752,360...80,769,973
Ensembl chr 4:80,752,360...80,769,956 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17109
    vision/eye phenotype 3193
      abnormal eye morphology 3035
        abnormal posterior eye segment morphology 1682
          abnormal optic nerve morphology 216
            small optic nerve 34
              optic nerve atrophy 18
Path 2
Term Annotations click to browse term
  mammalian phenotype 17109
    nervous system phenotype 4664
      abnormal nervous system morphology 3687
        abnormal somatic nervous system morphology 1272
          abnormal cranial nerve morphology 386
            abnormal optic nerve morphology 216
              small optic nerve 34
                optic nerve atrophy 18
paths to the root