Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal mammary gland morphology
go back to main search page
Accession:MP:0000627 term browser browse the term
Definition:any structural anomaly of the compound, alveolar and apocrine accessory gland of the skin of mammals that secretes milk
Comment:The neonatal male and female rat and mouse have 6 and 5 pairs of glands, respectively, with a single, central lactiferous duct, several branching secondary ducts, and numerous tertiary ducts (Ceriani 1970; Cardiff and Wellings 1999). In the rat, the glands are distributed in pairs along the milk line, with 1 pair cervical, 2 thoracic, 1 abdominal, and 2 inguinal (Astwood, Geschickter, and Rausch 1937). Distribution in the mouse is in the neck, chest wall (2 pairs), abdominal wall, and inguinal region (Cardiff and Wellings 1999).
Synonyms:exact_synonym: abnormal glandula mammaria morphology;   abnormal lactiferous gland morphology;   abnormal mammary glands;   mammary gland dysplasia
 related_synonym: abnormal Brustdruese morphology;   abnormal dug morphology;   abnormal lobe of mammary gland morphology;   abnormal mamma morphology;   abnormal mammae morphology


show annotations for term's descendants           Sort by:
abnormal mammary gland alveolus morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edaradd EDAR associated via death domain IAGP DNA:missense mutation:exon:p.Pro153Ser(rat) RGD PMID:22013926 RGD:14398762 NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447 		JBrowse link
G EdaraddswhKyo EDAR-associated death domain;swh Kyo mutant IAGP DNA:missense mutation:exon:p.Pro153Ser(rat) RGD PMID:22013926 RGD:14398762
abnormal mammary gland development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated IMP RGD PMID:16964288 RGD:1599505 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Brca2m1Uwm BRCA2, DNA repair associated; mutation 1, University of Wisconsin-Madison IMP RGD PMID:16964288 RGD:1599505
G Esr1 estrogen receptor 1 IMP RGD PMID:24506075 RGD:8552987 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr1em1Soar estrogen receptor 1; ZFN induced mutant 1, Soar IMP RGD PMID:24506075 RGD:8552987
abnormal mammary gland luminal epithelium morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:30893315 RGD:126908018 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1bem1Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 1, Musc IMP RGD PMID:30893315 RGD:126908018
G Cdkn1bem4Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 4, Musc IMP RGD PMID:30893315 RGD:126908018
mammary gland hypoplasia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edaradd EDAR associated via death domain IAGP in females, compared to heterozygous animals RGD PMID:15829729 RGD:2304219 NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447 		JBrowse link
G EdaraddswhKyo EDAR-associated death domain;swh Kyo mutant IAGP in females, compared to heterozygous animals RGD PMID:15829729 RGD:2304219
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5374
    integument phenotype 168
      abnormal skin adnexa morphology 166
        abnormal mammary gland morphology 99
          abnormal abdominal mammary gland morphology 0
          abnormal areola morphology 0
          abnormal cervical mammary gland morphology 0
          abnormal inguinal mammary gland morphology 0
          abnormal mammary gland connective tissue morphology 0
          abnormal mammary gland development + 7
          abnormal mammary gland epithelium morphology + 8
          abnormal mammary gland lobule morphology + 3
          abnormal mammary gland number + 0
          abnormal mammary gland stroma morphology 0
          abnormal nipple morphology + 0
          abnormal thoracic mammary gland morphology 0
          decreased mammary gland tumor incidence + 26
          increased mammary gland tumor incidence + 56
          mammary gland hyperplasia 0
          mammary gland hypoplasia 3
          pale mammary gland 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5374
    endocrine/exocrine gland phenotype 391
      abnormal gland morphology 330
        abnormal exocrine gland morphology 116
          abnormal apocrine gland morphology 99
            abnormal mammary gland morphology 99
              abnormal abdominal mammary gland morphology 0
              abnormal areola morphology 0
              abnormal cervical mammary gland morphology 0
              abnormal inguinal mammary gland morphology 0
              abnormal mammary gland connective tissue morphology 0
              abnormal mammary gland development + 7
              abnormal mammary gland epithelium morphology + 8
              abnormal mammary gland lobule morphology + 3
              abnormal mammary gland number + 0
              abnormal mammary gland stroma morphology 0
              abnormal nipple morphology + 0
              abnormal thoracic mammary gland morphology 0
              decreased mammary gland tumor incidence + 26
              increased mammary gland tumor incidence + 56
              mammary gland hyperplasia 0
              mammary gland hypoplasia 3
              pale mammary gland 0
paths to the root