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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased cell proliferation
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Accession:MP:0000351 term browser browse the term
Definition:increase in the expansion rate of a cell population by cell division


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increased cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 IDA RGD PMID:12668975 RGD:704417 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:18683040 RGD:4892578 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Lpin1m1Hubr lipin 1; ENU induced mutant 1, Hubr IMP compared to Wild type RGD PMID:21715287 RGD:38599010
increased mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:30893315 RGD:126908018 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1bem1Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 1, Musc IMP RGD PMID:30893315 RGD:126908018
G Cdkn1bem4Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 4, Musc IMP RGD PMID:30893315 RGD:126908018
increased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Themis thymocyte selection associated IAGP DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr 1:16,433,906...16,623,889
Ensembl chr 1:16,432,631...16,664,329 		JBrowse link
G Themism1Adej thymocyte selection associated; mutant1, Adej IAGP compared to BN RGD PMID:22275874 RGD:38599149
Term paths to the root
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  mammalian phenotype 5417
    cellular phenotype 184
      abnormal cell physiology 143
        abnormal cell proliferation 25
          increased cell proliferation 18
            increased B cell proliferation 0
            increased CD8-positive, alpha-beta memory T cell proliferation 0
            increased Schwann cell proliferation 0
            increased Sertoli cell proliferation 0
            increased T cell proliferation 6
            increased cerebellar granule cell precursor proliferation 0
            increased chondrocyte proliferation 0
            increased endothelial cell proliferation 0
            increased fetal cardiomyocyte proliferation 0
            increased fibroblast proliferation 0
            increased granulosa cell proliferation 0
            increased hematopoietic stem cell proliferation 0
            increased hepatocyte proliferation 1
            increased inner cell mass proliferation 0
            increased keratinocyte proliferation 0
            increased kidney cell proliferation 0
            increased lung endothelial cell proliferation 0
            increased macrophage proliferation 0
            increased mammary gland epithelial cell proliferation 5
            increased megakaryocyte progenitor cell proliferation 0
            increased melanoblast proliferation 0
            increased mesenchymal cell proliferation involved in lung development 0
            increased myoblast proliferation 0
            increased neural crest cell proliferation + 0
            increased osteoblast proliferation 0
            increased pancreatic alpha cell proliferation 0
            increased pancreatic beta cell proliferation 0
            increased pancreatic endocrine progenitor cell proliferation 0
            increased skeletal muscle satellite cell proliferation 0
            increased splenocyte proliferation 1
            increased trophectoderm cell proliferation 0
            increased vascular endothelial cell proliferation 0
            increased vascular smooth muscle cell proliferation 0
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