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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased granulocyte number
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Accession:MP:0000334 term browser browse the term
Definition:fewer than expected number of leukocytes that have abundant granules in the cytoplasm, including basophils, neutrophils, and eosinophils
Synonyms:exact_synonym: agranulocytosis;   granulocytopenia;   reduced granulocyte number
 alt_id: MP:0000723


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absent mast cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:1912576 RGD:5133424 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G KitWs KIT proto-oncogene receptor tyrosine kinase; mutant 1 IMP RGD PMID:1912576 RGD:5133424
decreased eosinophil cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Fh fumarate hydratase IMP RGD PMID:27556703 RGD:13792708 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fhem1 fumarate hydratase; TALEN induced mutant 1 IMP RGD PMID:27556703 RGD:13792708
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:23799078 RGD:13462048 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:23799078 RGD:13462048
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5372
    immune system phenotype 493
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal leukocyte cell number 134
              decreased leukocyte cell number 89
                decreased granulocyte number 14
                  decreased basophil cell number + 0
                  decreased eosinophil cell number + 11
                  decreased mast cell number + 3
                  decreased neutrophil cell number + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5372
    hematopoietic system phenotype 243
      abnormal hematopoietic system morphology/development 223
        abnormal hematopoietic cell morphology 179
          abnormal myeloid cell morphology 102
            abnormal myeloid leukocyte morphology 64
              abnormal granulocyte morphology 43
                abnormal granulocyte number 43
                  decreased granulocyte number 14
                    decreased basophil cell number + 0
                    decreased eosinophil cell number + 11
                    decreased mast cell number + 3
                    decreased neutrophil cell number + 0
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