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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal aorta morphology
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Accession:MP:0000272 term browser browse the term
Definition:any structural anomaly of the main trunk of the systemic arterial system that originates from the base of the left ventricle of the heart and extends to the abdomen at the point where it branches into the common iliac arteries
Synonyms:exact_synonym: Abnormal aortic morphology;   abnormal aortae morphology;   aorta abnormalities
 narrow_synonym: aorta dysplasia
 xref: Fyler:1453;   HP:0001679;   MA:0000062


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abnormal aorta morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IMP RGD PMID:29166645 RGD:150520219 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apoeem1Ejt apolipoprotein E; TALEN induced mutant 1, Ejt IMP RGD PMID:29166645 RGD:150520219
G Apoeem1Sage apolipoprotein E; endonuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:29166645 RGD:150520219
increased aorta wall thickness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddah1 dimethylarginine dimethylaminohydrolase 1 exacerbates
induces		 IMP compared to wild type RGD PMID:31402164 PMID:31402164 RGD:151347602, RGD:151347602 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddah1em1Ywxu dimethylarginine dimethylaminohydrolase 1; CRISPR/Cas9 induced mutant 1, Ywxu induces
exacerbates		 IMP compared to wild type RGD PMID:31402164 PMID:31402164 RGD:151347602, RGD:151347602
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5420
    cardiovascular system phenotype 1371
      abnormal cardiovascular system morphology 427
        abnormal blood vessel morphology 114
          abnormal artery morphology 66
            abnormal systemic artery morphology 54
              abnormal aorta morphology 52
                abnormal aorta wall morphology + 16
                abnormal aortic mass 4
                abnormal aortic weight + 26
                abnormal descending aorta morphology + 1
                abnormal thoracic aorta morphology + 1
                aorta coarctation + 0
                aorta hypoplasia + 0
                aorta pulmonary collateral arteries + 0
                aorta stenosis + 0
                aortic cartilaginous metaplasia 0
                aortic dissection 0
                aortic hypertrophy 0
                aortopulmonary window 0
                calcified aorta + 0
                dilated aorta + 0
                increased aorta tortuosity 0
                interrupted aorta + 0
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