MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: abnormal systemic arterial blood pressure
Accession: MP:0000230
browse the term
Definition: altered tension of the blood within the systemic arteries
Synonyms: exact_synonym: heart/cardiovascular system: blood pressure anomalies
alt_id: MP:0001594; MP:0002129
xref: MGI:2173589
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Bmal1
basic helix-loop-helix ARNT like 1
IMP
compared to wild type
RGD
PMID:32306766
RGD:155598602
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
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Bmal1em1Mcwi
basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi
IMP
compared to wild type
RGD
PMID:32306766
RGD:155598602
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Cd247
Cd247 molecule
induced
IMP
compared to wild-type
RGD
PMID:24343121 PMID:24343121
RGD:13442481 , RGD:13442481
NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248
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Cd247em1Mcwi
Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
induced
IMP
compared to wild-type
RGD
PMID:24343121 PMID:24343121
RGD:13442481 , RGD:13442481
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Cd36
CD36 molecule
IMP
RGD
PMID:22128087
RGD:6893560
NCBI chr 4:18,209,088...18,302,142
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Clcn6
chloride voltage-gated channel 6
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:163,715,593...163,748,301
Ensembl chr 5:163,717,439...163,748,198
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Gper1
G protein-coupled estrogen receptor 1
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
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Gper1em1Bj
G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
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Hvcn1
hydrogen voltage-gated channel 1
IMP
RGD
PMID:24935944
RGD:14985214
NCBI chr12:40,001,205...40,030,671
Ensembl chr12:40,001,498...40,042,020
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Mc4r
melanocortin 4 receptor
IMP
RGD
PMID:24400148
RGD:13825242
NCBI chr18:62,689,798...62,691,685
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Mc4rm1Hubr
melanocortin 4 receptor; ENU induced mutation 1, Hubr
IMP
RGD
PMID:24400148
RGD:13825242
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Nox4
NADPH oxidase 4
induced
IMP
compared to SS/JrHsdMcwi
RGD
PMID:26644237 PMID:26644237
RGD:11085830 , RGD:11085830
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
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Nox4em2Mcwi
NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
induced
IMP
compared to SS/JrHsdMcwi
RGD
PMID:26644237 PMID:26644237
RGD:11085830 , RGD:11085830
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P2rx7
purinergic receptor P2X 7
IMP
RGD
PMID:31630543
RGD:14995937
NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
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Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
compared to female wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
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Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
compared to female wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
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Ren
renin
sexual_dimorphism
IMP
compared to wild type compared to wild type male
RGD
PMID:21242461 PMID:21242461
RGD:7771614 , RGD:7771614
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
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Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
sexual_dimorphism
IMP
compared to wild type compared to wild type male
RGD
PMID:21242461 PMID:21242461
RGD:7771614 , RGD:7771614
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Gper1
G protein-coupled estrogen receptor 1
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
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Gper1em1Bj
G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
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Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:39,014,822...39,066,716
Ensembl chr 8:39,037,992...39,066,715
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Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
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Ncf2
neutrophil cytosolic factor 2
induces
IMP
compared to wild-type littermates
RGD
PMID:22326221 PMID:22326221
RGD:9587793 , RGD:9587793
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
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Ncf2em1Mcwi
neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1,Mcwi
induces
IMP
compared to wild-type littermates
RGD
PMID:22326221 PMID:22326221
RGD:9587793 , RGD:9587793
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Nox4
NADPH oxidase 4
induced
IMP
compared to SS/JrHsdMcwi
RGD
PMID:26644237 PMID:26644237
RGD:11085830 , RGD:11085830
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
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Nox4em2Mcwi
NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
induced
IMP
compared to SS/JrHsdMcwi
RGD
PMID:26644237 PMID:26644237
RGD:11085830 , RGD:11085830
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Plekha7
pleckstrin homology domain containing A7
IMP
compared to wild type
RGD
PMID:25136115 PMID:25136115
RGD:11079199 , RGD:11079199
NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:179,799,040...179,982,281
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Plekha7em4Mcwi
pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:25136115 PMID:25136115
RGD:11079199 , RGD:11079199
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Sh2b3
SH2B adaptor protein 3
IMP
RGD
PMID:25776069
RGD:13442483
NCBI chr12:40,391,755...40,414,336
Ensembl chr12:40,392,633...40,414,335
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Sh2b3em1Mcwi
SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:25776069
RGD:13442483
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Adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
IAGP
DNA:polymorphism
RGD
PMID:19423552
RGD:2312639
NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:34,258,899...34,388,952
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Hmox1
heme oxygenase 1
IDA
RGD
PMID:12215473
RGD:1580453
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hvcn1
hydrogen voltage-gated channel 1
IMP
RGD
PMID:24935944
RGD:14985214
NCBI chr12:40,001,205...40,030,671
Ensembl chr12:40,001,498...40,042,020
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Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
NCBI chr10:96,489,329...96,520,745
Ensembl chr10:96,460,331...96,566,075
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Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
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Adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
IMP
As compared to SS parents
RGD
PMID:23185005
RGD:9685162
NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:34,258,899...34,388,952
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Adamts16em1Bj
ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj
IMP
As compared to SS parents
RGD
PMID:23185005
RGD:9685162
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Bmal1
basic helix-loop-helix ARNT like 1
IMP
compared to wild type
RGD
PMID:32306766
RGD:155598602
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
G
Bmal1em1Mcwi
basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi
IMP
compared to wild type
RGD
PMID:32306766
RGD:155598602
G
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
IMP
RGD
PMID:31327268
RGD:18899561
NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058
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Camk2n1em1Tja
calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja
IMP
RGD
PMID:31327268
RGD:18899561
G
Clcn6
chloride voltage-gated channel 6
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:163,715,593...163,748,301
Ensembl chr 5:163,717,439...163,748,198
G
Gper1
G protein-coupled estrogen receptor 1
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
G
Gper1em1Bj
G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
G
Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
compared to female wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
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Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
compared to female wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
G
Ren
renin
sexual_dimorphism
IMP
compared to wild type compared to wild type male
RGD
PMID:21242461 PMID:21242461
RGD:7771614 , RGD:7771614
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
sexual_dimorphism
IMP
compared to wild type male
RGD
PMID:21242461 PMID:21242461
RGD:7771614 , RGD:7771614
G
Adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
IMP
As compared to SS parents
RGD
PMID:23185005
RGD:9685162
NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:34,258,899...34,388,952
G
Adamts16em1Bj
ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj
IMP
As compared to SS parents
RGD
PMID:23185005
RGD:9685162
G
Bmal1
basic helix-loop-helix ARNT like 1
IMP
compared to wild type
RGD
PMID:32306766
RGD:155598602
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
G
Bmal1em1Mcwi
basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi
IMP
compared to wild type
RGD
PMID:32306766
RGD:155598602
G
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
IMP
RGD
PMID:31327268
RGD:18899561
NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058
G
Camk2n1em1Tja
calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja
IMP
RGD
PMID:31327268
RGD:18899561
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Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740
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Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
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Gper1
G protein-coupled estrogen receptor 1
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
G
Gper1em1Bj
G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
G
Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
compared to female wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
G
Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
compared to female wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
G
Ren
renin
sexual_dimorphism
IMP
compared to wild type compared to wild type male
RGD
PMID:21242461 PMID:21242461
RGD:7771614 , RGD:7771614
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
sexual_dimorphism
IMP
compared to wild type male
RGD
PMID:21242461 PMID:21242461
RGD:7771614 , RGD:7771614
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Lepr
leptin receptor
IMP IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:27465994 PMID:30278832
RGD:12911217 , RGD:401960095
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
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Nppb
natriuretic peptide B
IMP
RGD
PMID:26063669
RGD:12910116
NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310
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Nppbem2Mcwi
natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:26063669
RGD:12910116
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Alms1
ALMS1, centrosome and basal body associated protein
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:119,683,076...119,783,471
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Alms1em1Mcwi
Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
G
Lepr
leptin receptor
IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:32710530
RGD:401960103
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
G
Nppa
natriuretic peptide A
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
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Rag1
recombination activating 1
IMP
on 4% NaCl diet
RGD
PMID:23364523
RGD:7207429
NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:108,371,978...108,383,261
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Rag1em1Mcwi
recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
on 4% NaCl diet
RGD
PMID:23364523
RGD:7207429
G
Rag1em2Mcwi
recombination activating gene 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
on 4% NaCl diet
RGD
PMID:23364523
RGD:7207429
G
Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
G
Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
G
Sod3
superoxide dismutase 3
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
G
Sod3m1Mcwi
superoxide dismutase 3; mutation 1, Medical College of Wisconsin
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
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Tmem67
transmembrane protein 67
IAGP
RGD
PMID:11095650
RGD:1300514
NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:30,333,793...30,386,666
G
Tmem67wpk
transmembrane protein 67; wpk mutant
IAGP
RGD
PMID:11095650
RGD:1300514
G
Tph2
tryptophan hydroxylase 2
sexual_dimorphism
IMP
RGD
PMID:32909922 PMID:36169206
RGD:597830145 , RGD:597830153
NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:52,571,911...52,675,639
G
Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
G
Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
G
Apoe
apolipoprotein E
IMP
RGD
PMID:29166645
RGD:150520219
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
G
Apoeem1Ejt
apolipoprotein E; TALEN induced mutant 1, Ejt
IMP
RGD
PMID:29166645
RGD:150520219
G
Apoeem1Sage
apolipoprotein E; endonuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:29166645
RGD:150520219
G
Ddx52
DExD-box helicase 52
IAGP
DNA:polymorphism
RGD
PMID:17218081
RGD:1599269
NCBI chr10:69,322,062...69,344,856
Ensembl chr10:69,322,114...69,428,714
G
Ednrb
endothelin receptor type B
IDA
RGD
PMID:16179487
RGD:1581856
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
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Glp1r
glucagon-like peptide 1 receptor
IDA
RGD
PMID:12093887
RGD:625448
NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,973,352...9,011,654
G
Kcnmb1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
IDA
RGD
PMID:14551242
RGD:1298970
NCBI chr10:19,062,014...19,119,005
Ensembl chr10:19,062,291...19,073,204
G
Npr1
natriuretic peptide receptor 1
IAGP
RGD
PMID:7629399
RGD:1357231
NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:178,231,766...178,247,088
G
Ren
renin
IAGP
RGD
PMID:8567976
RGD:61046
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
G
Tnf
tumor necrosis factor
IAGP
RGD
PMID:9590569
RGD:1357163
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
Nppa
natriuretic peptide A
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
G
Npr1
natriuretic peptide receptor 1
IAGP
RGD
PMID:12511524
RGD:628585
NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:178,231,766...178,247,088
G
Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
RGD
PMID:29906243
RGD:38596340
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
G
Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
RGD
PMID:29906243
RGD:38596340
G
Sod3
superoxide dismutase 3
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
G
Sod3m1Mcwi
superoxide dismutase 3; mutation 1, Medical College of Wisconsin
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
G
Add1
adducin 1
IAGP
RGD
PMID:15474463
RGD:1302895
NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
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Adora2b
adenosine A2B receptor
IMP
RGD
PMID:26385692
RGD:11533328
NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091
G
Adora2bem2Mcwi
adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:26385692
RGD:11533328
G
Alms1
ALMS1, centrosome and basal body associated protein
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:119,683,076...119,783,471
G
Alms1em1Mcwi
Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
G
Cyp11b1
cytochrome P450, family 11, subfamily b, polypeptide 1
IAGP
RGD
PMID:7981756
RGD:69709
NCBI chr 7:108,653,385...108,660,062
Ensembl chr 7:108,653,378...108,660,995 Ensembl chr 7:108,653,378...108,660,995
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Ednra
endothelin receptor type A
IDA
RGD
PMID:16157796
RGD:1581830
NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284
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Egln1
egl-9 family hypoxia-inducible factor 1
IAGP
DNA:duplication
RGD
PMID:20231529
RGD:11251783
NCBI chr19:69,765,276...69,804,681
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Kcnq1
potassium voltage-gated channel subfamily Q member 1
IAGP
DNA:deletion:exon (rat)
RGD
PMID:16368876
RGD:1581602
NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:207,721,131...208,054,072
G
Kcnq1dfk
potassium voltage-gated channel subfamily Q member 1;deafness Kyoto
IAGP
RGD
PMID:16368876
RGD:1581602
G
Lepr
leptin receptor
treatment onset
IAGP IMP
compared to treated compared to SS/JrHsdMcwi
RGD
PMID:23154293 PMID:33568522 PMID:27465994
RGD:13432147 , RGD:401965412 , RGD:12911217
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:27465994
RGD:12911217
G
Leprfa
leptin receptor; fa mutant
IAGP
RGD
PMID:23154293
RGD:13432147
G
Nppa
natriuretic peptide A
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
G
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110
G
Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457
G
Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
G
Sod3
superoxide dismutase 3
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
G
Sod3m1Mcwi
superoxide dismutase 3; mutation 1, Medical College of Wisconsin
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
G
Alms1
ALMS1, centrosome and basal body associated protein
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:119,683,076...119,783,471
G
Alms1em1Mcwi
Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
G
Astn1
astrotactin 1
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:73,070,754...73,388,902
Ensembl chr13:73,071,267...73,388,895
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Brinp2
BMP/retinoic acid inducible neural specific 2
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:72,964,498...73,065,312
Ensembl chr13:72,964,502...73,065,294
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Btg2
BTG anti-proliferation factor 2
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
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Cd247
Cd247 molecule
severity
IMP
RGD
PMID:24343121
RGD:13442481
NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248
G
Cd247em1Mcwi
Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
severity
IMP
RGD
PMID:24343121
RGD:13442481
G
Chi3l1
chitinase 3 like 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825
G
Chit1
chitinase 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:48,117,886...48,165,645
Ensembl chr13:48,145,893...48,165,639
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Cop1
COP1, E3 ubiquitin ligase
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:73,954,058...74,095,283
Ensembl chr13:73,963,145...74,095,269
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Etnk2
ethanolamine kinase 2
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:47,362,964...47,381,100
Ensembl chr13:47,363,060...47,381,100
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Fmod
fibromodulin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183
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Gpr37l1
G protein-coupled receptor 37-like 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:49,150,355...49,157,204
Ensembl chr13:49,150,359...49,157,204
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
IMP
RGD
PMID:26077568
RGD:13800514
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
G
Hsd11b2em1Jmul
hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul
IMP
RGD
PMID:26077568
RGD:13800514
G
Ipo9
importin 9
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:49,362,244...49,414,477
Ensembl chr13:49,365,716...49,414,477
G
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:39,014,822...39,066,716
Ensembl chr 8:39,037,992...39,066,715
G
Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
G
Lgr6
leucine-rich repeat-containing G protein-coupled receptor 6
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:48,976,193...49,095,870
Ensembl chr13:48,976,193...49,095,857
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Mgat5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:41,228,327...41,516,462
Ensembl chr13:41,228,360...41,516,461
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Mmp9
matrix metallopeptidase 9
ameliorates
IMP
RGD
PMID:37423509
RGD:597805897
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
G
Mmp9em6Mcwi
matrix metallopeptidase 9; CRISPR/Cas9 system induced mutant 6, Medical College of Wisconsin
ameliorates
IMP
RGD
PMID:37423509
RGD:597805897
G
Mybph
myosin binding protein H
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:48,205,162...48,212,928
Ensembl chr13:48,205,269...48,212,928
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Ncf2
neutrophil cytosolic factor 2
ameliorates
IMP
compared to wild-type littermates
RGD
PMID:22326221
RGD:9587793
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
G
Ncf2em1Mcwi
neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1,Mcwi
ameliorates
IMP
compared to wild-type littermates
RGD
PMID:22326221
RGD:9587793
G
Nckap5
NCK-associated protein 5
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:39,922,576...40,835,849
Ensembl chr13:39,922,737...40,835,521
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Nox4
NADPH oxidase 4
severity
IMP
RGD
PMID:26644237
RGD:11085830
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
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Optc
opticin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:47,906,145...47,920,334
Ensembl chr13:47,906,197...47,917,416
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Pappa2
pappalysin 2
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:73,407,385...73,683,699
Ensembl chr13:73,407,385...73,681,568
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Plekha6
pleckstrin homology domain containing A6
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:47,166,899...47,307,003
Ensembl chr13:47,167,160...47,307,003
G
Plekha7
pleckstrin homology domain containing A7
ameliorates
IMP
compared to wild type
RGD
PMID:25136115
RGD:11079199
NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:179,799,040...179,982,281
G
Plekha7em4Mcwi
pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin
ameliorates
IMP
compared to wild type
RGD
PMID:25136115
RGD:11079199
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Prelp
proline and arginine rich end leucine rich repeat protein
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324
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Psme2-ps1
proteasome activator subunit 2, pseudogene 1
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:40,742,081...40,742,929
G
Ptprv
protein tyrosine phosphatase, receptor type, V
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:49,099,922...49,120,247
Ensembl chr13:49,099,925...49,120,121
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Ren
renin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
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Resp18
regulated endocrine-specific protein 18
IMP
RGD
PMID:29570433
RGD:14348960
NCBI chr 9:84,213,844...84,220,186
Ensembl chr 9:84,213,467...84,221,299
G
Resp18em2Mcwi
regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:29570433
RGD:14348960
G
Rnpep
arginyl aminopeptidase
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:49,251,259...49,271,440
Ensembl chr13:49,251,264...49,269,799
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Sox13
SRY-box transcription factor 13
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:47,383,145...47,427,572
Ensembl chr13:47,383,145...47,435,663
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Syt2
synaptotagmin 2
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:48,639,634...48,749,814
Ensembl chr13:48,639,934...48,749,812
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Tmem163
transmembrane protein 163
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:41,520,595...41,693,938
Ensembl chr13:41,520,359...41,693,938
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Tnr
tenascin R
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:74,285,141...74,706,174
Ensembl chr13:74,507,366...74,701,115
G
Tuba1c-ps1
tubulin, alpha 1C, pseudogene 1
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:41,060,047...41,061,387
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