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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal circulating alkaline phosphatase level
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Accession:MP:0000202 term browser browse the term
Definition:any anomaly in the concentration in the blood of the enzyme which hydrolyzes orthophosphoric monoesters; low levels are seen in cases of hypophosphatasia
Synonyms:exact_synonym: abnormal AP level;   abnormal alkaline phosphatase level;   abnormal circulating ALP levels
 alt_id: MP:0001571
 xref: GO:0004035



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decreased circulating alkaline phosphatase level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Htr7 5-hydroxytryptamine receptor 7 IMP in male RGD PMID:31125290 RGD:14696717 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Htr7em1Msu 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu IMP in male RGD PMID:31125290 RGD:14696717
increased circulating alkaline phosphatase level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamp2 lysosomal-associated membrane protein 2 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:28124283 RGD:13703118 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:28124283 RGD:13703118
G P2ry2 purinergic receptor P2Y2 IMP RGD PMID:19155635 RGD:2316657 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5375
    homeostasis/metabolism phenotype 1399
      abnormal homeostasis 1300
        abnormal enzyme/coenzyme level 81
          abnormal circulating enzyme level 60
            abnormal circulating alkaline phosphatase level 12
              decreased circulating alkaline phosphatase level 7
              increased circulating alkaline phosphatase level 5
Path 2
Term Annotations click to browse term
  mammalian phenotype 5375
    homeostasis/metabolism phenotype 1399
      abnormal homeostasis 1300
        abnormal protein level 128
          abnormal circulating protein level 104
            abnormal circulating enzyme level 60
              abnormal circulating alkaline phosphatase level 12
                decreased circulating alkaline phosphatase level 7
                increased circulating alkaline phosphatase level 5
paths to the root