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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal microglial cell morphology
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Accession:MP:0000136 term browser browse the term
Definition:any structural anomaly of the small, migratory, phagocytic, interstitial cells derived from myeloid progenitor cells and found in the parenchyma of the central nervous system; microglia are scavengers, engulfing dead cells and other debris, and in Alzheimer's disease, microglia are found associated with dying nerve cells and amyloid plaques


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  mammalian phenotype 0
    nervous system phenotype 0
      abnormal nervous system morphology 0
        abnormal glial cell morphology 0
          abnormal CNS glial cell morphology 0
            abnormal microglial cell morphology 0
              abnormal microglial cell differentiation 0
              decreased microglial cell number 0
              microgliosis 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    hematopoietic system phenotype 0
      abnormal hematopoietic system morphology/development 0
        abnormal hematopoietic cell morphology 0
          abnormal myeloid cell morphology 0
            abnormal myeloid leukocyte morphology 0
              abnormal phagocyte morphology 0
                abnormal mononuclear phagocyte morphology 0
                  abnormal macrophage morphology 0
                    abnormal microglial cell morphology 0
                      abnormal microglial cell differentiation 0
                      decreased microglial cell number 0
                      microgliosis 0
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