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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Abnormal serum anion gap
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Accession:HP:0031961 term browser browse the term
Definition:Any deviation from the normal value of the serum anion gap, which is calculated from the electrolytes measured in the chemical laboratory, is defined as the sum of serum chloride and bicarbonate concentrations subtracted from the serum sodium concentration.
Comment:The determination of the anion gap is used in the detection and analysis of acid-base disorders, assessment of quality control in the chemical laboratory, and detection of such disorders as multiple myeloma, bromide intoxication, and lithium intoxication. The normal value can vary widely, reflecting both differences in the methods that are used to measure its constituents and substantial interindividual variability.


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of metabolism/homeostasis 0
        Abnormal homeostasis 0
          Abnormality of acid-base homeostasis 0
            Abnormal serum anion gap 0
              Decreased serum anion gap 0
              Elevated serum anion gap 0
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