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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:CNS demyelination
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Accession:HP:0007305 term browser browse the term
Definition:A loss of myelin from nerve fibers in the central nervous system.
Comment:CNS demyelination affects the white matter, which consists mostly of axons with their envelope of myelin, along with two types of neuroglia: oligo-dendrocytes and astrocytes.
Synonyms:exact_synonym: Demyelination in central white matter
 alt_id: HP:0007222
 xref: UMLS:C0338474


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system morphology 0
          Abnormal myelination 0
            Abnormal CNS myelination 0
              CNS demyelination 0
                Diffuse demyelination of the cerebral white matter 0
                Patchy demyelination of subcortical white matter 0
                Severe demyelination of the white matter 0
                Spinal cord posterior columns myelin loss 0
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