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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.

Term:Pituitary adenoma
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Accession:HP:0002893 term browser browse the term
Definition:A benign epithelial tumor derived from intrinsic cells of the adenohypophysis (anterior pituitary).
Comment:In most cases pituitary adenoma are histologically benign, slow-growing, small neoplasms confined to the sella turcica. Some pituitary adenomas are more aggressive, grow faster, invade surrounding tissues, and cause local symptoms such as visual disturbances, headache, and varying degrees of hypopituitarism. Pituitary adenoma can be described as microadenoma, macroadenoma, and giant tumors based on size. Microadenoma is a tumor less than 10 mm, while macroadenoma describes a tumor larger than 10mm. Giant pituitary tumors are bigger than 40 mm.
Synonyms:exact_synonym: Noncancerous tumor in pituitary gland;   Noncancerous tumour in pituitary gland;   Pituitary gland adenoma
 xref: ICD-O:M8272/0 "Pituitary adenoma";   NCI:C2855;   SNOMEDCT_US:128664001;   SNOMEDCT_US:254956000;   UMLS:C0032000



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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the endocrine system 0
        Neoplasm of the endocrine system 0
          Neoplasm of the pituitary gland 0
            Neoplasm of the anterior pituitary 0
              Pituitary adenoma 0
                Pituitary acidophilic stem cell adenoma 0
                Pituitary corticotropic cell adenoma 0
                Pituitary gonadotropic cell adenoma 0
                Pituitary growth hormone cell adenoma 0
                Pituitary macroadenoma 0
                Pituitary microadenoma 0
                Pituitary null cell adenoma 0
                Pituitary prolactin cell adenoma + 0
                Pituitary thyrotropic cell adenoma 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system morphology 0
          Morphological central nervous system abnormality 0
            Abnormal brain morphology 0
              Abnormal pituitary gland morphology 0
                Neoplasm of the pituitary gland 0
                  Neoplasm of the anterior pituitary 0
                    Pituitary adenoma 0
                      Pituitary acidophilic stem cell adenoma 0
                      Pituitary corticotropic cell adenoma 0
                      Pituitary gonadotropic cell adenoma 0
                      Pituitary growth hormone cell adenoma 0
                      Pituitary macroadenoma 0
                      Pituitary microadenoma 0
                      Pituitary null cell adenoma 0
                      Pituitary prolactin cell adenoma + 0
                      Pituitary thyrotropic cell adenoma 0
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