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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Increased circulating lactate concentration
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Accession:HP:0002151 term browser browse the term
Definition:Abnormally increased level of blood lactate (2-hydroxypropanoic acid). Lactate is produced from pyruvate by lactate dehydrogenase during normal metabolism. The terms lactate and lactic acid are often used interchangeably but lactate (the component measured in blood) is strictly a weak base whereas lactic acid is the corresponding acid. Lactic acidosis is often used clinically to describe elevated lactate but should be reserved for cases where there is a corresponding acidosis (pH below 7.35).
Synonyms:exact_synonym: Increased blood lactate;   Increased serum lactate
 broad_synonym: Higher than normal levels of lactate in blood
 alt_id: HP:0003638
 xref: UMLS:C1836440


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of metabolism/homeostasis 0
        Abnormal homeostasis 0
          Abnormality of acid-base homeostasis 0
            Acidosis 0
              Increased circulating lactate concentration 0
                Postprandial hyperlactemia 0
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