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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of stem cell differentiation
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Accession:GO:2000737 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.


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negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BBS12 Bardet-Biedl syndrome 12 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:22958920) MGI
Ensembl
PMID:22958920 GO_REF:0000107 NCBI chr 7:69,987,949...70,003,933
Ensembl chr 7:70,000,875...70,003,007
JBrowse link
G CCNK cyclin K acts_upstream_of_or_within ISO (PMID:22547058) MGI PMID:22547058 NCBI chr24:77,436,569...77,466,703
Ensembl chr24:77,436,479...77,467,322
JBrowse link
G CDK12 cyclin dependent kinase 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22547058) Ensembl
MGI
PMID:22547058 GO_REF:0000107 NCBI chr16:66,612,238...66,709,437
Ensembl chr16:66,623,785...66,708,755
JBrowse link
G CDK13 cyclin dependent kinase 13 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22547058) Ensembl
MGI
PMID:22547058 GO_REF:0000107 NCBI chr21:18,551,273...18,688,889
Ensembl chr21:18,553,446...18,688,525
JBrowse link
G ESRRB estrogen related receptor beta involved_in ISO (PMID:26206133) UniProt PMID:26206133 NCBI chr24:53,630,998...53,762,098 JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19303854) Ensembl
MGI
PMID:19303854 GO_REF:0000107 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243
JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:129,023,750...129,028,790
Ensembl chr20:129,027,370...129,028,065
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:81,879,532...81,890,684
Ensembl chr25:81,878,111...81,890,701
JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:27,484,699...27,521,108
Ensembl chr 2:27,484,760...27,522,504
JBrowse link
G LBH LBH regulator of WNT signaling pathway involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:77,278,080...77,306,721
Ensembl chr14:77,280,510...77,306,518
JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:17940068) MGI PMID:17940068 NCBI chr11:7,813,309...7,820,009 JBrowse link
G NCOA3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (PMID:22977234) MGI PMID:22977234 NCBI chr 2:16,270,218...16,423,381
Ensembl chr 2:16,273,717...16,423,318
JBrowse link
G NELFB negative elongation factor complex member B involved_in ISO (PMID:19340312) UniProt PMID:19340312 NCBI chr12:914,384...933,921 JBrowse link
G NELFB negative elongation factor complex member B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:913,493...932,063 JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25335925) Ensembl
MGI
PMID:25335925 GO_REF:0000107 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984
JBrowse link
G TBX3 T-box transcription factor 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18356246) MGI
Ensembl
PMID:18356246 GO_REF:0000107 NCBI chr11:109,952,100...109,966,328
Ensembl chr11:109,952,054...109,965,065
JBrowse link
G TRIM6 tripartite motif containing 6 involved_in ISO (PMID:22328504) UniProt PMID:22328504 NCBI chr 1:61,136,690...61,147,911 JBrowse link
G YAP1 Yes1 associated transcriptional regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:20516196) MGI
Ensembl
PMID:20516196 GO_REF:0000107 NCBI chr 1:93,479,478...93,605,340
Ensembl chr 1:93,479,135...93,606,808
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:104,041,657...104,078,705
Ensembl chr20:104,040,679...104,078,484
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:64,019,633...64,022,301
Ensembl chr14:64,019,418...64,026,281
JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:11,749,312...11,776,103
Ensembl chr 7:11,749,168...11,773,340
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:38,696,771...38,819,324
Ensembl chr11:38,694,602...38,718,519
JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:41,230,675...41,251,177
Ensembl chr23:41,231,364...41,251,150
JBrowse link
G LOC103214263 NEDD4 binding protein 2 like 2 involved_in ISO (PMID:19506020) UniProt PMID:19506020 NCBI chr 3:11,191,215...11,287,434
Ensembl chr 3:11,197,302...11,285,607
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339
JBrowse link
G TCF15 transcription factor 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:55,909,945...55,916,186
Ensembl chr 2:55,910,030...55,915,600
JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in ISO (PMID:7694679) UniProt PMID:7694679 NCBI chr  X:11,454,090...11,456,268 JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11588035) Ensembl
MGI
PMID:11588035 GO_REF:0000107 NCBI chr 6:34,011,073...34,013,665
Ensembl chr 6:34,011,031...34,013,870
JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239
JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:11,749,312...11,776,103
Ensembl chr 7:11,749,168...11,773,340
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19822
    negative regulation of biological process 5968
      negative regulation of developmental process 1005
        negative regulation of cell differentiation 721
          negative regulation of stem cell differentiation 31
            negative regulation of cardioblast differentiation + 1
            negative regulation of hematopoietic stem cell differentiation 6
            negative regulation of mesenchymal stem cell differentiation + 2
            negative regulation of neural crest cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 19822
    cellular process 19340
      cellular developmental process 4596
        cell differentiation 4595
          regulation of cell differentiation 1705
            regulation of stem cell differentiation 76
              negative regulation of stem cell differentiation 31
                negative regulation of cardioblast differentiation + 1
                negative regulation of hematopoietic stem cell differentiation 6
                negative regulation of mesenchymal stem cell differentiation + 2
                negative regulation of neural crest cell differentiation + 0
paths to the root