Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of stem cell differentiation
go back to main search page
Accession:GO:2000737 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.


show annotations for term's descendants           Sort by:
negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbs12 Bardet-Biedl syndrome 12 acts_upstream_of_or_within ISO
IEA		 MGI:5444297 (PMID:22958920)
GO_REF:0000107		 RGD
Ensembl		 PMID:22958920 GO_REF:0000107 NCBI chr 2:120,203,396...120,221,024
Ensembl chr 2:120,203,428...120,219,255 		JBrowse link
G Ccnk cyclin K acts_upstream_of_or_within ISO (PMID:22547058) RGD PMID:22547058 NCBI chr 6:132,854,428...132,877,604
Ensembl chr 6:127,090,569...127,113,191 		JBrowse link
G Cdk12 cyclin-dependent kinase 12 acts_upstream_of_or_within ISO
IEA		 (PMID:22547058)
GO_REF:0000107		 RGD
Ensembl		 PMID:22547058 GO_REF:0000107 NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,201,211...83,280,888
Ensembl chr10:83,201,211...83,280,888 		JBrowse link
G Cdk13 cyclin-dependent kinase 13 acts_upstream_of_or_within ISO
IEA		 (PMID:22547058)
GO_REF:0000107		 RGD
Ensembl		 PMID:22547058 GO_REF:0000107 NCBI chr17:51,945,975...52,040,218
Ensembl chr17:47,251,163...47,341,721 		JBrowse link
G Esrrb estrogen-related receptor beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:26206133)		 UniProt
RGD		 PMID:26206133 GO_REF:0000024 NCBI chr 6:111,738,662...111,894,087
Ensembl chr 6:106,008,095...106,160,791 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO
IEA		 MGI:2661097 (PMID:19303854)
GO_REF:0000107		 RGD
Ensembl		 PMID:19303854 GO_REF:0000107 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19682396)		 Ensembl
RGD		 PMID:19682396 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO
ISS		 (PMID:19682396)
GO_REF:0000024		 RGD
UniProt		 PMID:19682396 GO_REF:0000024 NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:21235343)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21235343 GO_REF:0000024 GO_REF:0000107 NCBI chr13:92,609,791...92,618,580
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in ISO
IEA		 (PMID:19682396)
GO_REF:0000107		 RGD
Ensembl		 PMID:19682396 GO_REF:0000107 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Lbh LBH regulator of WNT signaling pathway involved_in ISO
IEA		 (PMID:25655704)
GO_REF:0000107		 RGD
Ensembl		 PMID:25655704 GO_REF:0000107 NCBI chr 6:28,321,040...28,344,855
Ensembl chr 6:22,568,834...22,593,079 		JBrowse link
G Mir125a microRNA 125a acts_upstream_of_or_within ISO MGI:1921298 (PMID:22751012) RGD PMID:22751012 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO
IEA		 (PMID:17940068)
GO_REF:0000107		 RGD
Ensembl		 PMID:17940068 GO_REF:0000107 NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (PMID:22977234) RGD PMID:22977234 NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Nelfb negative elongation factor complex member B involved_in ISO
IEA		 (PMID:19340312)
GO_REF:0000107		 RGD
Ensembl		 PMID:19340312 GO_REF:0000107 NCBI chr 3:8,010,883...8,027,403
Ensembl chr 3:8,010,888...8,027,403 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA		 (PMID:19682396)
GO_REF:0000107		 RGD
Ensembl		 PMID:19682396 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO
IEA		 (PMID:25335925)
GO_REF:0000107		 RGD
Ensembl		 PMID:25335925 GO_REF:0000107 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO
IEA		 MGI:3769504 (PMID:18356246)
GO_REF:0000107		 RGD
Ensembl		 PMID:18356246 GO_REF:0000107 NCBI chr12:42,540,378...42,555,490
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO
IEA		 (PMID:22328504)
GO_REF:0000107		 RGD
Ensembl		 PMID:22328504 GO_REF:0000107 NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO
IEA		 (PMID:20516196)
GO_REF:0000107		 RGD
Ensembl		 PMID:20516196 GO_REF:0000107 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO
IEA		 (PMID:32169943)
GO_REF:0000107		 RGD
Ensembl		 PMID:32169943 GO_REF:0000107 NCBI chr 5:149,665,467...149,693,127
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO
IEA		 (PMID:23748442)
GO_REF:0000107		 RGD
Ensembl		 PMID:23748442 GO_REF:0000107 NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rest RE1-silencing transcription factor involved_in ISO
ISS
IEA		 (PMID:20942606)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:20942606 GO_REF:0000024 GO_REF:0000107 NCBI chr14:31,213,415...31,233,451
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 (PMID:21199191)
GO_REF:0000107		 RGD
Ensembl		 PMID:21199191 GO_REF:0000107 NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa9 heat shock protein family A (Hsp70) member 9 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21123823)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21123823 GO_REF:0000024 GO_REF:0000107 NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 involved_in ISO (PMID:19506020) RGD PMID:19506020 NCBI chr12:4,972,967...5,038,027
Ensembl chr12:103,590...197,784 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA		 (PMID:23434824)
GO_REF:0000107		 RGD
Ensembl		 PMID:23434824 GO_REF:0000107 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Tcf15 transcription factor 15 involved_in ISO
IEA		 (PMID:32669716)
GO_REF:0000107		 RGD
Ensembl		 PMID:32669716 GO_REF:0000107 NCBI chr 3:161,099,301...161,105,083
Ensembl chr 3:140,638,984...140,644,766 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked involved_in ISO (PMID:7694679) RGD PMID:7694679 NCBI chr  X:30,761,611...30,763,612
Ensembl chr  X:27,128,610...27,146,667
Ensembl chr10:27,128,610...27,146,667 		JBrowse link
G Zfp36 zinc finger protein 36 acts_upstream_of_or_within ISO MGI:2652418 (PMID:11588035) RGD PMID:11588035 NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO
IEA		 (PMID:24023731)
GO_REF:0000107		 RGD
Ensembl		 PMID:24023731 GO_REF:0000107 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Mir154 microRNA 154 acts_upstream_of_or_within ISO (PMID:25959411) RGD PMID:25959411 NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA		 (PMID:18570921)
GO_REF:0000107		 RGD
Ensembl		 PMID:18570921 GO_REF:0000107 NCBI chr14:31,213,415...31,233,451
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    negative regulation of biological process 5837
      negative regulation of developmental process 1114
        negative regulation of cell differentiation 803
          negative regulation of stem cell differentiation 32
            negative regulation of cardioblast differentiation + 1
            negative regulation of hematopoietic stem cell differentiation 6
            negative regulation of mesenchymal stem cell differentiation + 3
            negative regulation of neural crest cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular developmental process 4833
        cell differentiation 4832
          regulation of cell differentiation 1788
            regulation of stem cell differentiation 82
              negative regulation of stem cell differentiation 32
                negative regulation of cardioblast differentiation + 1
                negative regulation of hematopoietic stem cell differentiation 6
                negative regulation of mesenchymal stem cell differentiation + 3
                negative regulation of neural crest cell differentiation + 0
paths to the root