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ONTOLOGY REPORT - ANNOTATIONS

Term:osmolarity-sensing monoatomic cation channel activity
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Accession:GO:1990760 term browser browse the term
Definition:Enables the transmembrane transfer of a monoatomic cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.
Synonyms:broad_synonym: osmolarity-sensing cation channel activity


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osmolarity-sensing monoatomic cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel enables ISO
IEA		 (PMID:15548533)
GO_REF:0000107		 RGD
Ensembl		 PMID:15548533 GO_REF:0000107 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 enables IDA
IEA		 PMID:21084682
GO_REF:0000107		 Ensembl PMID:21084682 GO_REF:0000107, RGD:401966867 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Tmem63a transmembrane protein 63a enables ISO
IEA		 (PMID:27045885)
GO_REF:0000107		 RGD
Ensembl		 PMID:27045885 GO_REF:0000107 NCBI chr13:92,662,872...92,696,186
Ensembl chr13:92,663,968...92,696,183 		JBrowse link
G Tmem63b transmembrane protein 63B enables ISO (PMID:27045885), (PMID:31243992), (PMID:32375046) RGD PMID:27045885 PMID:31243992 PMID:32375046 NCBI chr 9:22,810,753...22,838,163
Ensembl chr 9:15,320,432...15,340,720 		JBrowse link
G Tmem63c transmembrane protein 63c enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:27045885)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27045885 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:18279313 RGD:10047048 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21100
    molecular function regulator activity 2301
      molecular sensor activity 68
        osmosensor activity 7
          osmolarity-sensing monoatomic cation channel activity 6
Path 2
Term Annotations click to browse term
  molecular_function 21100
    transporter activity 1274
      transmembrane transporter activity 1165
        passive transmembrane transporter activity 516
          channel activity 516
            monoatomic ion channel activity 457
              monoatomic cation channel activity 347
                osmolarity-sensing monoatomic cation channel activity 6
paths to the root