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ONTOLOGY REPORT - ANNOTATIONS


Term:survivin complex
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Accession:GO:1990713 term browser browse the term
Definition:A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC).
Comment:An example of this is BIRC5 in human (UniProt symbol O15392) in PMID:10949038 (inferred from physical interaction).
Synonyms:exact_synonym: Baculoviral IAP repeat-containing protein 5 complex
 narrow_synonym: survivin homodimer complex



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survivin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc5 baculoviral IAP repeat-containing 5 part_of ISO (PMID:10949038) RGD PMID:10949038 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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  cellular_component 20824
    protein-containing complex 6552
      nuclear protein-containing complex 1279
        survivin complex 1
Path 2
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  cellular_component 20824
    cellular anatomical structure 20625
      organelle 13967
        membrane-bounded organelle 12555
          intracellular membrane-bounded organelle 12003
            nucleus 7451
              nuclear protein-containing complex 1279
                survivin complex 1
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