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ONTOLOGY REPORT - ANNOTATIONS

Term:IRE1-TRAF2-ASK1 complex
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Accession:GO:1990604 term browser browse the term
Definition:A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).
Synonyms:related_synonym: ERN1-TRAF2-ASK1 complex


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IRE1-TRAF2-ASK1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 part_of ISO
IBA
IEA		 (PMID:23000344)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:23000344 GO_REF:0000033 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 part_of IBA
ISO
IEA		 GO_REF:0000033
(PMID:12050113)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:12050113 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 part_of ISO
IEA		 (PMID:12050113), (PMID:23000344)
GO_REF:0000107		 RGD
Ensembl		 PMID:12050113 PMID:23000344 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 part_of ISO
ISS
IBA
IEA		 (PMID:23000344)
GO_REF:0000024
(PMID:12050113)
GO_REF:0000033
GO_REF:0000107		 RGD
ParkinsonsUK-UCL
GO_Central
Ensembl		 PMID:12050113 PMID:23000344 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21366
    protein-containing complex 6834
      endoplasmic reticulum protein-containing complex 142
        IRE1-TRAF2-ASK1 complex 4
Path 2
Term Annotations click to browse term
  cellular_component 21366
    cellular anatomical structure 21071
      organelle 14293
        intracellular organelle 13882
          intracellular membrane-bounded organelle 12309
            endoplasmic reticulum 1913
              endoplasmic reticulum subcompartment 1125
                endoplasmic reticulum membrane 1115
                  IRE1-TRAF2-ASK1 complex 4
paths to the root