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ONTOLOGY REPORT - ANNOTATIONS


Term:Cry-Per complex
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Accession:GO:1990512 term browser browse the term
Definition:Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.
Comment:An example of this is Cry1 in mouse (P97784) in PMID:24855952 (inferred from physical interaction).



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Cry-Per complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry2 cryptochrome circadian regulator 2 part_of ISO
IEA
(PMID:20840750)
GO_REF:0000107
RGD
Ensembl
PMID:20840750 GO_REF:0000107 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Pasd1 PAS domain containing repressor 1 part_of ISO (PMID:25936801) RGD PMID:25936801 NCBI chr  X:149,617,933...149,639,214
Ensembl chr  X:149,620,972...149,638,675
JBrowse link
G Per2 period circadian regulator 2 part_of ISO (PMID:20840750) RGD PMID:20840750 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20824
    protein-containing complex 6552
      nuclear protein-containing complex 1279
        Cry-Per complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20824
    cellular anatomical structure 20625
      intracellular anatomical structure 15180
        intracellular organelle 13561
          intracellular membrane-bounded organelle 12003
            nucleus 7451
              nuclear protein-containing complex 1279
                Cry-Per complex 3
paths to the root