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ONTOLOGY REPORT - ANNOTATIONS

Term:lysosomal protein catabolic process
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Accession:GO:1905146 term browser browse the term
Definition:Any cellular protein catabolic process that takes place in a lysosome.
Comment:Also consider annotating to the term 'autophagy ; GO:0006914' or one of its descendants.
Synonyms:exact_synonym: cellular protein breakdown in lysosome;   cellular protein catabolic process in lysosome;   cellular protein catabolism in lysosome;   cellular protein degradation in lysosome;   lysosomal protein catabolism;   lysosomal protein degradation
 related_synonym: lysosomal proteolysis;   proteolysis within lysosome


show annotations for term's descendants           Sort by:
lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within ISO MGI:4460281 (PMID:30930081) RGD PMID:30930081 NCBI chr12:17,207,315...17,222,975
Ensembl chr12:12,093,834...12,108,511 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO
IEA		 (PMID:10527801), (PMID:17855597)
GO_REF:0000107		 RGD
Ensembl		 PMID:10527801 PMID:17855597 GO_REF:0000107 NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Cst7 cystatin F involved_in ISO
IEA		 (PMID:15752368), (PMID:22365146)
GO_REF:0000107		 RGD
Ensembl		 PMID:15752368 PMID:22365146 GO_REF:0000107 NCBI chr 3:159,857,221...159,865,987
Ensembl chr 3:139,396,850...139,405,557 		JBrowse link
G Ctsh cathepsin H involved_in ISO
IEA		 (PMID:15752368)
GO_REF:0000107		 RGD
Ensembl		 PMID:15752368 GO_REF:0000107 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Dpp7 dipeptidylpeptidase 7 acts_upstream_of_or_within ISO
IEA		 (PMID:28728022)
GO_REF:0000107		 RGD
Ensembl		 PMID:28728022 GO_REF:0000107 NCBI chr 3:28,563,240...28,567,492
Ensembl chr 3:8,165,091...8,169,355 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26392287)		 Ensembl
RGD		 PMID:26392287 GO_REF:0000107 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Grn granulin precursor acts_upstream_of_or_within ISO MGI:3762618 (PMID:28728022) RGD PMID:28728022 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO
IEA
ISS		 (PMID:24880125)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24880125 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO
IEA		 (PMID:27654426)
GO_REF:0000107		 RGD
Ensembl		 PMID:27654426 GO_REF:0000107 NCBI chr 2:125,749,994...125,784,689
Ensembl chr 2:123,816,614...123,857,971 		JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase acts_upstream_of ISO MGI:1857830 (PMID:25592972), (PMID:26467158) RGD PMID:25592972 PMID:26467158 NCBI chr 7:111,708,353...111,761,825
Ensembl chr 7:111,675,730...111,762,026 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:12813057) RGD PMID:12813057 NCBI chr20:28,756,951...28,783,422
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Slc17a9 solute carrier family 17 member 9 acts_upstream_of_or_within ISO (PMID:24962569) RGD PMID:24962569 NCBI chr 3:167,839,246...167,857,462
Ensembl chr 3:167,839,385...167,855,985 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (PMID:28728022) RGD PMID:28728022 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28296633)		 UniProt
Ensembl
RGD		 PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108 		JBrowse link
G Tpp1 tripeptidyl peptidase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:28728022)
GO_REF:0000107		 RGD
Ensembl		 PMID:28728022 GO_REF:0000107 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A involved_in ISO
IEA		 (PMID:30709847)
GO_REF:0000107		 RGD
Ensembl		 PMID:30709847 GO_REF:0000107 NCBI chr 1:223,328,784...223,555,500
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
negative regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
IEA
ISS		 (PMID:25588945)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:25588945 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:67,319,438...67,362,547
Ensembl chr 7:65,434,394...65,477,383 		JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISS
ISO		 GO_REF:0000024
MGI:1857830 (PMID:25592972), (PMID:26467158)		 UniProt
RGD		 PMID:25592972 PMID:26467158 GO_REF:0000024 NCBI chr 7:111,708,353...111,761,825
Ensembl chr 7:111,675,730...111,762,026 		JBrowse link
G Usp8 ubiquitin specific peptidase 8 involved_in ISO
IEA		 (PMID:27444016)
GO_REF:0000107		 RGD
Ensembl		 PMID:27444016 GO_REF:0000107 NCBI chr 3:134,413,832...134,463,040
Ensembl chr 3:113,962,164...114,009,666 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO
IEA		 (PMID:26203154)
GO_REF:0000107		 RGD
Ensembl		 PMID:26203154 GO_REF:0000107 NCBI chr19:37,938,989...37,974,887
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
positive regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:22383525)		 Ensembl
RGD		 PMID:22383525 GO_REF:0000107 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO
IEA		 (PMID:23152628)
GO_REF:0000107		 RGD
Ensembl		 PMID:23152628 GO_REF:0000107 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISO (PMID:9228033) RGD PMID:9228033 NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Marchf2 membrane associated ring-CH-type finger 2 involved_in ISO
IEA		 (PMID:29573664)
GO_REF:0000107		 RGD
Ensembl		 PMID:29573664 GO_REF:0000107 NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794 		JBrowse link
regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO
IEA		 UniProtKB:Q9CTG6 (PMID:23499937), (PMID:24334770)
GO_REF:0000107
(PMID:24334770)		 RGD
Ensembl		 PMID:23499937 PMID:24334770 GO_REF:0000107 NCBI chr 5:158,575,727...158,595,157
Ensembl chr 5:153,292,751...153,312,139 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO
IEA		 (PMID:29514215)
GO_REF:0000107		 RGD
Ensembl		 PMID:29514215 GO_REF:0000107 NCBI chr 2:125,749,994...125,784,689
Ensembl chr 2:123,816,614...123,857,971 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        catabolic process 2956
          macromolecule catabolic process 1709
            protein catabolic process 1211
              protein catabolic process in the vacuole 27
                lysosomal protein catabolic process 25
                  negative regulation of lysosomal protein catabolic process 4
                  positive regulation of lysosomal protein catabolic process 4
                  regulation of lysosomal protein catabolic process + 10
paths to the root