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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of response to endoplasmic reticulum stress
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Accession:GO:1903573 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
Synonyms:exact_synonym: down regulation of ER stress response;   down regulation of cellular response to endoplasmic reticulum stress;   down regulation of response to ER stress;   down regulation of response to endoplasmic reticulum stress;   downregulation of ER stress response;   downregulation of cellular response to endoplasmic reticulum stress;   downregulation of response to ER stress;   downregulation of response to endoplasmic reticulum stress;   negative regulation of ER stress response;   negative regulation of cellular response to endoplasmic reticulum stress;   negative regulation of response to ER stress
 narrow_synonym: inhibition of ER stress response;   inhibition of cellular response to endoplasmic reticulum stress;   inhibition of response to ER stress;   inhibition of response to endoplasmic reticulum stress

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negative regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in ISO (PMID:28694473) UniProt PMID:28694473 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Aqp11 aquaporin 11 involved_in ISO (PMID:18606867) UniProt PMID:18606867 NCBI chrNW_004955414:14,245,682...14,260,717
Ensembl chrNW_004955414:14,245,682...14,260,717 		JBrowse link
G Clu clusterin involved_in ISO (PMID:21803450) ARUK-UCL PMID:21803450 NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISO (PMID:24206663) UniProt PMID:24206663 NCBI chrNW_004955413:4,571,028...4,605,097
Ensembl chrNW_004955413:4,571,028...4,605,097 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1 group H member 2 involved_in ISO (PMID:24206663) UniProt PMID:24206663 NCBI chrNW_004955559:731,630...736,973
Ensembl chrNW_004955559:730,670...737,505 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 involved_in ISO (PMID:24206663) UniProt PMID:24206663 NCBI chrNW_004955422:940,310...954,170
Ensembl chrNW_004955422:940,310...949,049 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:23035048) UniProt PMID:23035048 NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610 		JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta involved_in ISO (PMID:9837962) UniProt PMID:9837962 NCBI chrNW_004955437:582,083...592,026
Ensembl chrNW_004955437:582,431...591,810 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:20160352) ParkinsonsUK-UCL PMID:20160352 RGD:10047363 NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 BCL2 like 1 involved_in ISO (PMID:29507230) UniProt PMID:29507230 NCBI chrNW_004955422:29,254,440...29,307,104
Ensembl chrNW_004955422:29,254,216...29,308,174 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:16940180) ParkinsonsUK-UCL PMID:16940180 NCBI chrNW_004955472:564,227...568,708
Ensembl chrNW_004955472:564,493...568,491 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3 like 1 involved_in ISO PMID:15665855
(PMID:15665855) 		ParkinsonsUK-UCL PMID:15665855 RGD:1558627 NCBI chrNW_004955422:1,702,131...1,734,603
Ensembl chrNW_004955422:1,700,692...1,734,773 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within ISO (PMID:22240901) MGI PMID:22240901 NCBI chrNW_004955454:2,657,374...2,660,591
Ensembl chrNW_004955454:2,658,490...2,660,021 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (PMID:15102845) ParkinsonsUK-UCL PMID:15102845 NCBI chrNW_004955433:14,609,275...14,621,774
Ensembl chrNW_004955433:14,608,375...14,621,839 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:23453807) ParkinsonsUK-UCL PMID:23453807 NCBI chrNW_004955580:1,053,823...1,069,802
Ensembl chrNW_004955580:1,053,823...1,069,802 		JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:21857923) ParkinsonsUK-UCL PMID:21857923 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923 		JBrowse link
G Opa1 OPA1 mitochondrial dynamin like GTPase involved_in ISO (PMID:23453807) ParkinsonsUK-UCL PMID:23453807 NCBI chrNW_004955420:14,927,490...15,007,082
Ensembl chrNW_004955420:14,923,575...15,007,081 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:14652021) ParkinsonsUK-UCL PMID:14652021 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (PMID:20811152) MGI PMID:20811152 NCBI chrNW_004955497:7,281,886...7,307,969 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:10973942), (PMID:21113145)
(PMID:21113145)
(PMID:11439185), (PMID:12150907), (PMID:23453807) 		ParkinsonsUK-UCL PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:21216966) ParkinsonsUK-UCL PMID:21216966 NCBI chrNW_004955445:7,754,313...7,819,229
Ensembl chrNW_004955445:7,754,319...7,819,275 		JBrowse link
G Selenos selenoprotein S involved_in ISO (PMID:17210132) BHF-UCL PMID:17210132 NCBI chrNW_004955416:28,152,984...28,162,173
Ensembl chrNW_004955416:28,153,460...28,162,095 		JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within 		ISO (PMID:12459480), (PMID:17059562)
(PMID:15611074) 		ParkinsonsUK-UCL
MGI		 PMID:12459480 PMID:15611074 PMID:17059562 NCBI chrNW_004955422:20,067,933...20,074,947
Ensembl chrNW_004955422:20,068,848...20,073,850 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within 		ISO (PMID:21075086)
(PMID:22240901) 		ParkinsonsUK-UCL
MGI		 PMID:21075086 PMID:22240901 NCBI chrNW_004955547:335,344...358,503
Ensembl chrNW_004955547:335,275...358,503 		JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within ISO (PMID:18628206) MGI PMID:18628206 NCBI chrNW_004955464:7,070,555...7,094,991
Ensembl chrNW_004955464:7,070,555...7,094,981 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:16571599) BHF-UCL PMID:16571599 NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:19135031)
PMID:20625543 		ParkinsonsUK-UCL PMID:19135031 PMID:20625543 RGD:10047191 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in ISO (PMID:17116640) ParkinsonsUK-UCL PMID:17116640 NCBI chrNW_004955412:20,149,104...20,161,378
Ensembl chrNW_004955412:20,148,953...20,161,172 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:17116640)
(PMID:23453807) 		ParkinsonsUK-UCL PMID:17116640 PMID:23453807 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor involved_in ISO (PMID:18391022) UniProt PMID:18391022 NCBI chrNW_004955408:25,718,523...25,769,551
Ensembl chrNW_004955408:25,719,187...25,774,555 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25239945) UniProt PMID:25239945 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in ISO (PMID:18606867) UniProt PMID:18606867 NCBI chrNW_004955414:14,245,682...14,260,717
Ensembl chrNW_004955414:14,245,682...14,260,717 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO (PMID:23129660) UniProt PMID:23129660 NCBI chrNW_004955495:5,025,038...5,051,810
Ensembl chrNW_004955495:5,031,229...5,052,389 		JBrowse link
G Svip small VCP interacting protein involved_in ISO PMID:17000876
(PMID:17872946) 		ParkinsonsUK-UCL
UniProt		 PMID:17000876 PMID:17872946 RGD:10047192 NCBI chrNW_004955476:3,231,789...3,236,602 JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chrNW_004955599:526,792...529,825
Ensembl chrNW_004955599:526,966...529,735 		JBrowse link
G Ubxn2a UBX domain protein 2A involved_in ISO (PMID:26265139) UniProt PMID:26265139 NCBI chrNW_004955469:6,173,524...6,214,568
Ensembl chrNW_004955469:6,173,524...6,214,568 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chrNW_004955402:9,710,080...9,737,601
Ensembl chrNW_004955402:9,710,080...9,743,077 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO (PMID:22590560) ParkinsonsUK-UCL PMID:22590560 NCBI chrNW_004955407:17,429,299...17,572,138
Ensembl chrNW_004955407:17,429,299...17,575,262 		JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chrNW_004955442:4,229,236...4,255,623
Ensembl chrNW_004955442:4,226,756...4,255,623 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28128204), (PMID:32160526) UniProt PMID:28128204 PMID:32160526 NCBI chrNW_004955415:14,085,404...14,098,220
Ensembl chrNW_004955415:14,085,404...14,098,856 		JBrowse link
G Pdia6 protein disulfide isomerase family A member 6 involved_in ISO (PMID:24508390) WB PMID:24508390 NCBI chrNW_004955487:5,735,698...5,744,601
Ensembl chrNW_004955487:5,735,698...5,748,015 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:19328063) UniProt PMID:19328063 NCBI chrNW_004955547:335,344...358,503
Ensembl chrNW_004955547:335,275...358,503 		JBrowse link
G Ufl1 UFM1 specific ligase 1 involved_in ISO (PMID:32160526) UniProt PMID:32160526 NCBI chrNW_004955411:22,548,139...22,577,287
Ensembl chrNW_004955411:22,548,219...22,580,903 		JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (PMID:27030769) ARUK-UCL PMID:27030769 NCBI chrNW_004955495:6,818,002...6,838,177
Ensembl chrNW_004955495:6,815,562...6,836,772 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:21954288) UniProt PMID:21954288 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in ISO (PMID:21954288) UniProt PMID:21954288 NCBI chrNW_004955578:950,258...1,004,438
Ensembl chrNW_004955578:967,593...1,004,438 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 involved_in ISO (PMID:21954288) UniProt PMID:21954288 NCBI chrNW_004955406:6,907,876...7,163,672 JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:30842412) UniProt PMID:30842412 NCBI chrNW_004955415:14,085,404...14,098,220
Ensembl chrNW_004955415:14,085,404...14,098,856 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISO (PMID:11907036) UniProt PMID:11907036 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:14676213) ParkinsonsUK-UCL PMID:14676213 NCBI chrNW_004955501:1,867,956...1,963,091 JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO (PMID:14676213) ParkinsonsUK-UCL PMID:14676213 NCBI chrNW_004955470:10,487,962...10,593,046
Ensembl chrNW_004955470:10,487,481...10,593,046 		JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:21216966) ParkinsonsUK-UCL PMID:21216966 NCBI chrNW_004955445:7,754,313...7,819,229
Ensembl chrNW_004955445:7,754,319...7,819,275 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12628
    cellular process 12059
      negative regulation of cellular process 4628
        negative regulation of response to endoplasmic reticulum stress 44
          negative regulation of ERAD pathway 7
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 19
          negative regulation of endoplasmic reticulum unfolded protein response + 17
Path 2
Term Annotations click to browse term
  biological_process 12628
    biological regulation 9097
      regulation of biological process 8796
        regulation of response to stimulus 3532
          regulation of response to stress 1264
            regulation of cellular response to stress 472
              regulation of response to endoplasmic reticulum stress 79
                negative regulation of response to endoplasmic reticulum stress 44
                  negative regulation of ERAD pathway 7
                  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 19
                  negative regulation of endoplasmic reticulum unfolded protein response + 17
paths to the root