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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of protein maturation
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Accession:GO:1903317 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of protein maturation.



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regulation of protein maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:6113512 (PMID:28817564) RGD PMID:28817564 NCBI chr17:706,863...717,828 JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in ISO
IEA
(PMID:18725990)
GO_REF:0000107
RGD
Ensembl
PMID:18725990 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664 JBrowse link
G Kng2 kininogen 2 IDA RGD PMID:6685967 RGD:11062094 NCBI chr11:77,913,876...77,936,247 JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:50,557,722...50,606,569 JBrowse link
G Ctsz cathepsin Z involved_in ISO
IEA
(PMID:19433310)
GO_REF:0000107
RGD
Ensembl
PMID:19433310 GO_REF:0000107 NCBI chr 3:163,224,875...163,235,645 JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
ISO
IBA
GO_REF:0000107
(PMID:19855083)
GO_REF:0000033
(PMID:18835034), (PMID:19855083), (PMID:8508955)
Ensembl
RGD
GO_Central
PMID:8508955 PMID:18835034 PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr12:25,237,977...25,248,356 JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA
(PMID:19855083)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866 JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,272,400...60,280,506 JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:125,510,250...125,525,402 JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871 JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (PMID:17344476) RGD PMID:17344476 NCBI chr19:51,402,178...51,471,572 JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
ISS
(PMID:22445366)
GO_REF:0000024
RGD
UniProt
PMID:22445366 GO_REF:0000024 NCBI chr 3:126,796,131...126,799,352 JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057 JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,487,716...4,490,701 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764|MGI:97513 (PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 NCBI chr19:39,124,892...39,224,178 JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 NCBI chr 9:42,384,280...42,424,726 JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:124,706,246...124,867,234 JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:55,176,558...55,201,757 JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:105,136,521...105,139,596 JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945 JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:30249802)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30249802 GO_REF:0000024 GO_REF:0000107 NCBI chr10:65,796,173...65,807,082 JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192 JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440 JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:9836589) RGD PMID:9836589 NCBI chr 8:78,986,252...79,022,638 JBrowse link
G Clec3b C-type lectin domain family 3, member B involved_in ISS
ISO
GO_REF:0000024
(PMID:12694198)
UniProt
RGD
PMID:12694198 GO_REF:0000024 NCBI chr 8:122,810,120...122,815,837 JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:12666133) RGD PMID:12666133 NCBI chr 5:160,719,951...160,731,337 JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA
(PMID:89876)
GO_REF:0000107
RGD
Ensembl
PMID:89876 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664 JBrowse link
G Hpn hepsin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16908524)
UniProt
Ensembl
RGD
PMID:16908524 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,337,085...86,352,785 JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:68,884,446...68,906,300 JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:19897580)
GO_Central
RGD
PMID:19897580 GO_REF:0000033 NCBI chr 1:236,512,574...236,526,858 JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 IDA RGD PMID:11027681 RGD:67924 NCBI chr 4:122,489,754...122,524,666 JBrowse link
G S100a10 S100 calcium binding protein A10 involved_in ISO
IEA
(PMID:9836589)
GO_REF:0000107
RGD
Ensembl
PMID:9836589 GO_REF:0000107 NCBI chr 2:179,221,012...179,229,659 JBrowse link
positive regulation of protein maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfr2 transferrin receptor 2 involved_in ISO UniProtKB:P61769|UniProtKB:Q07891|UniProtKB:Q30201 (PMID:18353247) RGD PMID:18353247 NCBI chr12:19,107,673...19,124,622 JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl8 angiopoietin-like 8 acts_upstream_of_or_within ISO (PMID:23150577) RGD PMID:23150577 NCBI chr 8:20,376,462...20,378,488 JBrowse link
G Astl astacin like metalloendopeptidase involved_in ISO (PMID:22472438) RGD PMID:22472438 NCBI chr 3:114,563,135...114,580,295 JBrowse link
G Bag2 BAG cochaperone 2 involved_in ISO (PMID:16207813) RGD PMID:16207813 NCBI chr 9:35,970,033...35,980,677 JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 involved_in ISO (PMID:24552833) RGD PMID:24552833 NCBI chr18:61,849,821...62,093,876 JBrowse link
G Cntn2 contactin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18278038)
GO_REF:0000107
RGD
Ensembl
PMID:18278038 GO_REF:0000107 NCBI chr13:43,942,868...43,975,973 JBrowse link
G Ctnnd1 catenin delta 1 acts_upstream_of_or_within ISO MGI:98397 (PMID:17344476) RGD PMID:17344476 NCBI chr 3:90,090,025...90,141,247 JBrowse link
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within ISO MGI:4346364 (PMID:19877275) RGD PMID:19877275 NCBI chr 1:95,379,542...95,384,532 JBrowse link
G Mbl2 mannose binding lectin 2 IDA Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Mmp14 matrix metallopeptidase 14 IMP RGD PMID:14668206 RGD:1582606 NCBI chr15:27,887,795...27,897,020 JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:15064403) RGD PMID:15064403 NCBI chr 1:29,442,898...29,470,839 JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:20,991,785...21,018,254 JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:22795130)
UniProt
RGD
PMID:22795130 GO_REF:0000024 NCBI chr 9:83,630,037...83,748,690 JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16227578)
Ensembl
RGD
PMID:16227578 GO_REF:0000107 NCBI chr 1:177,363,526...177,662,689 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:105100 (PMID:17344476) RGD PMID:17344476 NCBI chr 3:166,511,616...166,559,463 JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A IMP RGD PMID:9756630 RGD:13463485 NCBI chr13:46,731,117...46,742,604 JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 IMP RGD PMID:9756630 RGD:13463485 NCBI chr16:7,410,308...7,436,392 JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:28366643)
UniProt
RGD
PMID:28366643 GO_REF:0000024 NCBI chr 9:74,594,463...74,595,072 JBrowse link
G Tnp2 transition protein 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:28366643)
UniProt
Ensembl
RGD
PMID:28366643 GO_REF:0000024 GO_REF:0000107 NCBI chr10:4,879,812...4,880,540 JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in IEA
ISO
GO_REF:0000107
(PMID:23325791)
Ensembl
RGD
PMID:23325791 GO_REF:0000107 NCBI chr 3:38,982,605...39,035,849 JBrowse link
G Myh9 myosin, heavy chain 9 involved_in IEA
ISO
GO_REF:0000107
(PMID:23325791)
Ensembl
RGD
PMID:23325791 GO_REF:0000107 NCBI chr 7:111,224,291...111,304,963 JBrowse link
regulation of protein activation cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rasal2 RAS protein activator like 2 involved_in ISO (PMID:31408278) RGD PMID:31408278 NCBI chr13:69,279,882...69,569,161 JBrowse link
regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) RGD PMID:10924275 NCBI chr 1:181,156,071...181,169,458 JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within ISO (PMID:34380733) RGD PMID:34380733 NCBI chr14:34,754,279...34,800,530 JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (PMID:15930098) RGD PMID:15930098 NCBI chr 3:151,672,505...151,696,975 JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:1859153|MGI:3027342 (PMID:15930098), (PMID:16254602) RGD PMID:15930098 PMID:16254602 NCBI chr15:31,573,325...31,666,068 JBrowse link
G Inpp5b inositol polyphosphate-5-phosphatase B acts_upstream_of_or_within ISO MGI:2159609 (PMID:11784089) RGD PMID:11784089 NCBI chr 5:136,996,766...137,061,315 JBrowse link
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 acts_upstream_of_or_within ISO (PMID:21795536) RGD PMID:21795536 NCBI chr 3:88,239,529...88,481,340 JBrowse link
G Notch4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) RGD PMID:24667410 NCBI chr20:4,160,362...4,184,466 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97760 (PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189 JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97592 (PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 NCBI chr 2:238,297,140...238,389,317 JBrowse link
G Prss37 serine protease 37 involved_in ISO (PMID:27649891) RGD PMID:27649891 NCBI chr 4:69,322,977...69,334,555 JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO MGI:3799278 (PMID:19887680) RGD PMID:19887680 NCBI chr 7:18,853,065...19,015,378 JBrowse link
G Rnf139 ring finger protein 139 involved_in ISO (PMID:19706601) RGD PMID:19706601 NCBI chr 7:90,439,726...90,450,911 JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) RGD PMID:16585392 NCBI chr 1:55,178,988...55,454,271 JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:143,757,389...143,770,430 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      metabolic process 12157
        macromolecule metabolic process 9981
          protein metabolic process 5231
            regulation of protein metabolic process 2024
              regulation of protein maturation 67
                negative regulation of protein maturation + 21
                positive regulation of protein maturation + 31
                regulation of N-terminal peptidyl-lysine acetylation + 0
                regulation of N-terminal peptidyl-methionine acetylation + 0
                regulation of protein activation cascade + 1
                regulation of protein processing + 64
Path 2
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological process 13375
        regulation of cellular process 13013
          regulation of metabolic process 6834
            regulation of macromolecule metabolic process 6302
              regulation of macromolecule biosynthetic process 5425
                regulation of gene expression 5308
                  regulation of protein maturation 67
                    negative regulation of protein maturation + 21
                    positive regulation of protein maturation + 31
                    regulation of N-terminal peptidyl-lysine acetylation + 0
                    regulation of N-terminal peptidyl-methionine acetylation + 0
                    regulation of protein activation cascade + 1
                    regulation of protein processing + 64
paths to the root