A translation repressor activity that acts by base-pairing with an mRNA. The binding can result in targeting the mRNA for degradation or interfering with mRNA translation, hence resulting in posttranscriptional gene silencing.
Comment:
This term is intended for microRNAs that act by base-pairing with a target mRNA.
Synonyms:
exact_synonym:
mRNA base-pairing posttranscriptional repressor activity; mRNA binding involved in PTGS; mRNA binding involved in post-transcriptional gene silencing; mRNA binding involved in posttranscriptional gene silencing; mRNA binding involved in quelling; translational inhibitor activity via mRNA base-pairing
broad_synonym:
RNA binding involved in PTGS; RNA binding involved in cosuppression; RNA binding involved in post-transcriptional gene silencing; RNA binding involved in posttranscriptional gene silencing; RNA binding involved in quelling; mRNA binding translation repressor activity
related_synonym:
mRNA base-pairing post-transcriptional repressor activity; mRNA binding involved in cosuppression