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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of dendritic spine maintenance
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Accession:GO:1902951 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.
Synonyms:exact_synonym: down regulation of dendritic spine maintenance;   downregulation of dendritic spine maintenance
 narrow_synonym: inhibition of dendritic spine maintenance


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negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) RGD PMID:24328732 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Cfl1 cofilin 1 involved_in IMP
NAS		 PMID:17360908 RGD
ARUK-UCL		 PMID:23974706 PMID:17360908 RGD:11570553, RGD:12793018 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P04925|UniProtKB:Q01097 (PMID:22820466)		 Ensembl
RGD		 PMID:22820466 GO_REF:0000107 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO UniProtKB:P04925|UniProtKB:P39688 (PMID:22820466) RGD PMID:22820466 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Prnp prion protein involved_in ISO
IEA		 ComplexPortal:CPX-1134|UniProtKB:P39688|UniProtKB:Q01097 (PMID:22820466), (PMID:24012003)
GO_REF:0000107		 RGD
Ensembl		 PMID:22820466 PMID:24012003 GO_REF:0000107 NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    negative regulation of biological process 5837
      negative regulation of cellular process 5609
        negative regulation of cellular component organization 809
          negative regulation of cell projection organization 227
            negative regulation of dendritic spine maintenance 5
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          cell projection organization 1889
            plasma membrane bounded cell projection organization 1849
              neuron projection organization 125
                dendritic spine organization 111
                  dendritic spine maintenance 28
                    regulation of dendritic spine maintenance 16
                      negative regulation of dendritic spine maintenance 5
paths to the root