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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of dendritic spine maintenance
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Accession:GO:1902951 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.
Synonyms:exact_synonym: down regulation of dendritic spine maintenance;   downregulation of dendritic spine maintenance
 narrow_synonym: inhibition of dendritic spine maintenance



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negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) RGD PMID:24328732 NCBI chr 1:88,481,889...88,485,816 JBrowse link
G Cfl1 cofilin 1 involved_in IMP
NAS
PMID:17360908 RGD
ARUK-UCL
PMID:23974706 PMID:17360908 RGD:11570553, RGD:12793018 NCBI chr 1:212,227,124...212,230,656 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P04925|UniProtKB:Q01097 (PMID:22820466)
Ensembl
RGD
PMID:22820466 GO_REF:0000107 NCBI chr20:44,322,635...44,514,498 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO UniProtKB:P04925|UniProtKB:P39688 (PMID:22820466) RGD PMID:22820466 NCBI chr 4:170,297,811...170,775,420 JBrowse link
G Prnp prion protein involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P39688|UniProtKB:Q01097 (PMID:22820466), (PMID:24012003) RGD PMID:22820466 PMID:24012003 NCBI chr 3:139,639,076...139,654,420 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    negative regulation of biological process 5816
      negative regulation of cellular process 5588
        negative regulation of cellular component organization 803
          negative regulation of cell projection organization 226
            negative regulation of dendritic spine maintenance 5
Path 2
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      cellular component organization or biogenesis 7187
        cellular component organization 6903
          cell projection organization 1883
            plasma membrane bounded cell projection organization 1843
              neuron projection organization 122
                dendritic spine organization 110
                  dendritic spine maintenance 28
                    regulation of dendritic spine maintenance 16
                      negative regulation of dendritic spine maintenance 5
paths to the root