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ONTOLOGY REPORT - ANNOTATIONS
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Term:
negative regulation of dendritic spine maintenance
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Accession:
GO:1902951
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Definition:
Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.
Synonyms:
exact_synonym:
down regulation of dendritic spine maintenance; downregulation of dendritic spine maintenance
narrow_synonym:
inhibition of dendritic spine maintenance
show annotations for term's descendants Sort by:
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object name
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reference
evidence
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Rat (5)
Mouse (5)
Human (6)
Chinchilla (5)
Bonobo (5)
Dog (5)
Squirrel (5)
Pig (5)
Green Monkey (5)
Naked Mole-rat (5)
All
Genes (5)
negative regulation of dendritic spine maintenance
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Apoe
apolipoprotein E
acts_upstream_of_or_within
ISO
(PMID:24328732)
RGD
PMID:24328732
NCBI chr 1:88,481,889...88,485,816
G
Cfl1
cofilin 1
involved_in
IMP
NAS
PMID:17360908
RGD
ARUK-UCL
PMID:23974706
PMID:17360908
RGD:11570553
,
RGD:12793018
NCBI chr 1:212,227,124...212,230,656
G
Fyn
FYN proto-oncogene, Src family tyrosine kinase
involved_in
IEA
ISO
GO_REF:0000107
UniProtKB:P04925|UniProtKB:Q01097 (PMID:22820466)
Ensembl
RGD
PMID:22820466
GO_REF:0000107
NCBI chr20:44,322,635...44,514,498
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
involved_in
ISO
UniProtKB:P04925|UniProtKB:P39688 (PMID:22820466)
RGD
PMID:22820466
NCBI chr 4:170,297,811...170,775,420
G
Prnp
prion protein
involved_in
ISO
ComplexPortal:CPX-1134|UniProtKB:P39688|UniProtKB:Q01097 (PMID:22820466), (PMID:24012003)
RGD
PMID:22820466
PMID:24012003
NCBI chr 3:139,639,076...139,654,420
Term paths to the root
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Path 1
Term
Annotations
biological_process
20534
negative regulation of biological process
5816
negative regulation of cellular process
5588
negative regulation of cellular component organization
803
negative regulation of cell projection organization
226
negative regulation of dendritic spine maintenance
5
Path 2
Term
Annotations
biological_process
20534
cellular process
19523
cellular component organization or biogenesis
7187
cellular component organization
6903
cell projection organization
1883
plasma membrane bounded cell projection organization
1843
neuron projection organization
122
dendritic spine organization
110
dendritic spine maintenance
28
regulation of dendritic spine maintenance
16
negative regulation of dendritic spine maintenance
5