regulation of leukocyte differentiation - Ontology Report

(PMID:19667090)

PMID:19667090

NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611

Indian hedgehog

involved_in

(PMID:19109233)

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

sonic hedgehog

acts_upstream_of_or_within

(PMID:10981962)

PMID:10981962

NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254

negative regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Flt3

FMS-like tyrosine kinase 3

acts_upstream_of_or_within

(PMID:16618805)

PMID:16618805

NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299

Hmgb3

high mobility group box 3

acts_upstream_of_or_within

(PMID:12714519)

PMID:12714519

NCBI chr X:70,599,523...70,604,261
Ensembl chr X:70,599,524...70,604,282

Id2

inhibitor of DNA binding 2

acts_upstream_of_or_within

(PMID:18523151)

PMID:18523151

NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139

Sfrp1

secreted frizzled-related protein 1

involved_in

(PMID:18941195)

PMID:18941195

GO_REF:0000119

NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648

negative regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cbfb

core binding factor beta

involved_in

(PMID:18258917)

NCBI chr 8:105,897,306...105,944,621
Ensembl chr 8:105,897,306...105,944,621

Hmgb1

high mobility group box 1

involved_in

GO_REF:0000119

NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299

runt related transcription factor 1

involved_in

(PMID:18258917)

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

Runx3

runt related transcription factor 3

involved_in

(PMID:18258917)

NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301

negative regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc4a2

solute carrier family 4 (anion exchanger), member 2

involved_in

(PMID:24515893)

PMID:24515893

NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948

Socs1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400

zinc finger and BTB domain containing 7B

involved_in

(PMID:22730529), (PMID:24880459)

PMID:22730529 PMID:24880459

NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083

negative regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

GO_REF:0000119

NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

involved_in

GO_REF:0000119

NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799

negative regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clec12a

C-type lectin domain family 12, member a

involved_in

IMP
ISS

(PMID:30787988)

PMID:30787988

GO_REF:0000024

NCBI chr 6:129,327,207...129,342,266
Ensembl chr 6:129,319,654...129,342,266

H2-M3

histocompatibility 2, M region locus 3

involved_in

GO_REF:0000119

NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375

Tmem176a

transmembrane protein 176A

acts_upstream_of_or_within

(PMID:20501748)

PMID:20501748

NCBI chr 6:48,818,417...48,822,298
Ensembl chr 6:48,817,853...48,824,005

Tmem176b

transmembrane protein 176B

involved_in
acts_upstream_of_or_within

(PMID:20501748)

PMID:20501748

GO_REF:0000033

NCBI chr 6:48,810,745...48,818,363
Ensembl chr 6:48,810,752...48,818,430

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

(PMID:22615127)

NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219

negative regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adipoq

adiponectin, C1Q and collagen domain containing

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778

C1qc

complement component 1, q subcomponent, C chain

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376

Ceacam1

CEA cell adhesion molecule 1

involved_in

(PMID:21029969)

PMID:21029969

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

Cul4a

cullin 4A

acts_upstream_of_or_within

(PMID:12393421)

PMID:12393421

NCBI chr 8:13,155,623...13,197,940
Ensembl chr 8:13,155,621...13,197,940

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(PMID:9620849)

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

Prdm16

PR domain containing 16

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 4:154,400,579...154,721,851
Ensembl chr 4:154,400,582...154,721,330

Rara

retinoic acid receptor, alpha

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768

runt related transcription factor 1

involved_in

GO_REF:0000119

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

(PMID:22615127)

NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219

negative regulation of immature T cell proliferation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bmp4

bone morphogenetic protein 4

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126

Cdkn2a

cyclin dependent kinase inhibitor 2A

involved_in

(PMID:15964995)

HGNC-UCL

PMID:15964995

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

Clec4g

C-type lectin domain family 4, member g

acts_upstream_of_or_within

(PMID:23487419)

PMID:23487419

NCBI chr 8:3,757,066...3,770,695
Ensembl chr 8:3,757,064...3,770,651

Erbb2

erb-b2 receptor tyrosine kinase 2

acts_upstream_of_or_within

(PMID:16230479)

PMID:16230479

NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542

Indian hedgehog

involved_in

(PMID:19109233)

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

Tmem131l

transmembrane 131 like

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 3:83,804,955...83,947,497
Ensembl chr 3:83,804,962...83,947,482

negative regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fbxo7

F-box protein 7

acts_upstream_of_or_within

(PMID:21652635)

PMID:21652635

NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737

negative regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adipoq

adiponectin, C1Q and collagen domain containing

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778

C1qc

complement component 1, q subcomponent, C chain

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376

Gata2

GATA binding protein 2

acts_upstream_of_or_within

(PMID:16254139)

PMID:16254139

NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014

Mir3107

microRNA 3107

involved_in

(PMID:25857263)

NCBI chr 8:23,632,589...23,632,678
Ensembl chr 8:23,632,589...23,632,678

Mir486

microRNA 486

involved_in

(PMID:25857263)

NCBI chr 8:23,632,571...23,632,698
Ensembl chr 8:23,632,571...23,632,698

Ptpn2

protein tyrosine phosphatase, non-receptor type 2

involved_in

(PMID:16705167)

PMID:16705167

NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665

Qki

quaking, KH domain containing RNA binding

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr17:10,425,480...10,538,706
Ensembl chr17:10,421,530...10,538,783

Thoc5

THO complex 5

acts_upstream_of_or_within

(PMID:10597251)

PMID:10597251

NCBI chr11:4,845,339...4,878,867
Ensembl chr11:4,845,320...4,878,867

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

(PMID:22615127)

NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219

negative regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Zfpm1

zinc finger protein, multitype 1

involved_in

(PMID:18063754)

PMID:18063754

NCBI chr 8:123,008,595...123,064,601
Ensembl chr 8:123,008,880...123,063,990

negative regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fgl2

fibrinogen-like protein 2

acts_upstream_of_or_within

(PMID:29341118)

PMID:29341118

NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372

negative regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apcs

amyloid P component, serum

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608

Bmyc

brain expressed myelocytomatosis oncogene

involved_in

GO_REF:0000119

NCBI chr 2:25,596,891...25,597,733
Ensembl chr 2:25,596,751...25,597,733

Cdk6

cyclin dependent kinase 6

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008

Gpr68

G protein-coupled receptor 68

acts_upstream_of_or_within

(PMID:19479052)

PMID:19479052

NCBI chr12:100,842,941...100,874,457
Ensembl chr12:100,842,941...100,874,457

Hoxa7

homeobox A7

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 6:52,191,471...52,198,757
Ensembl chr 6:52,191,471...52,198,834

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(PMID:9620849)

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

Mir125b-1

microRNA 125b-1

involved_in

(PMID:28389358)

PMID:28389358

NCBI chr 9:41,493,222...41,493,298
Ensembl chr 9:41,493,222...41,493,298

Mir125b-2

microRNA 125b-2

involved_in

(PMID:28389358)

PMID:28389358

NCBI chr16:77,443,161...77,443,231
Ensembl chr16:77,443,161...77,443,231

Myc

myelocytomatosis oncogene

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

(PMID:22615127)

NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219

negative regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lyn

LYN proto-oncogene, Src family tyrosine kinase

involved_in

(PMID:11672542)

PMID:11672542

NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122

Nme1

NME/NM23 nucleoside diphosphate kinase 1

involved_in

PMID:7737424

GO_REF:0000096 RGD:2299083

NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347

Nme2

NME/NM23 nucleoside diphosphate kinase 2

involved_in

PMID:7737424

GO_REF:0000096 RGD:2299083

NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085

negative regulation of natural killer cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pglyrp1

peptidoglycan recognition protein 1

acts_upstream_of_or_within

(PMID:20709292)

NCBI chr 7:18,618,615...18,624,363
Ensembl chr 7:18,605,256...18,624,384

Pglyrp2

peptidoglycan recognition protein 2

acts_upstream_of_or_within

(PMID:20709292)

NCBI chr17:32,631,433...32,643,157
Ensembl chr17:32,631,433...32,643,141

Pglyrp3

peptidoglycan recognition protein 3

acts_upstream_of_or_within

(PMID:20709292)

NCBI chr 3:91,919,784...91,939,979
Ensembl chr 3:91,921,890...91,938,889

Pglyrp4

peptidoglycan recognition protein 4

acts_upstream_of_or_within

(PMID:20709292)

NCBI chr 3:90,634,008...90,648,824
Ensembl chr 3:90,634,213...90,648,824

negative regulation of neutrophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

(PMID:9620849)

GO_REF:0000033

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

Trib1

tribbles pseudokinase 1

involved_in

(PMID:23515163)

PMID:23515163

NCBI chr15:59,520,503...59,528,948
Ensembl chr15:59,520,199...59,528,948

negative regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cldn18

claudin 18

acts_upstream_of_or_within

(PMID:22437732)

PMID:22437732

NCBI chr 9:99,572,849...99,599,320
Ensembl chr 9:99,571,514...99,599,320

Fbn1

fibrillin 1

involved_in

IDA
ISO

(PMID:24039232)

PMID:24039232

GO_REF:0000119

NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913

Fbxw7

F-box and WD-40 domain protein 7

involved_in

(PMID:29149593)

PMID:29149593

GO_REF:0000119

NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505

Ltf

lactotransferrin

involved_in

GO_REF:0000024

NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835

Tjp2

tight junction protein 2

acts_upstream_of_or_within

(PMID:22437732)

PMID:22437732

NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394

negative regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Calca

calcitonin/calcitonin-related polypeptide, alpha

involved_in

(PMID:10822112)

PMID:10822112

NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592

Cartpt

CART prepropeptide

involved_in

(PMID:16614075)

HGNC-UCL

PMID:16614075

NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599

Ccl3

C-C motif chemokine ligand 3

involved_in

GO_REF:0000024

NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181

Ceacam1

CEA cell adhesion molecule 1

acts_upstream_of_or_within

(PMID:25490771)

PMID:25490771

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

Clec2d

C-type lectin domain family 2, member d

acts_upstream_of_or_within

(PMID:12374791)

PMID:12374791

NCBI chr 6:129,157,578...129,163,498
Ensembl chr 6:129,157,578...129,163,497

Clec2g

C-type lectin domain family 2, member g

acts_upstream_of_or_within

(PMID:12374791)

PMID:12374791

NCBI chr 6:128,911,344...128,961,670
Ensembl chr 6:128,911,344...128,961,670

Clec2i

C-type lectin domain family 2, member i

involved_in

(PMID:12374791)

PMID:12374791

NCBI chr 6:128,864,550...128,875,131
Ensembl chr 6:128,864,551...128,875,130

Ctnnb1

catenin beta 1

acts_upstream_of_or_within

(PMID:15866165)

PMID:15866165

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

Erfe

erythroferrone

acts_upstream_of

(PMID:34002695)

PMID:34002695

NCBI chr 1:91,293,033...91,301,939
Ensembl chr 1:91,294,152...91,301,939

Fbn1

fibrillin 1

involved_in

ISO
IDA

(PMID:24039232)

PMID:24039232

GO_REF:0000119

NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913

Fstl3

follistatin-like 3

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr10:79,613,108...79,618,464
Ensembl chr10:79,613,106...79,618,464

Gpr137

G protein-coupled receptor 137

involved_in

IBA

GO_REF:0000033

NCBI chr19:6,915,425...6,919,818
Ensembl chr19:6,915,425...6,919,848

Gpr137b

G protein-coupled receptor 137B

involved_in

IMP
IBA

(PMID:31173907)

PMID:31173907

GO_REF:0000033

NCBI chr13:13,528,035...13,568,250
Ensembl chr13:13,532,205...13,568,599

Gpr55

G protein-coupled receptor 55

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 1:85,860,927...85,924,781
Ensembl chr 1:85,866,039...85,888,729

Iapp

islet amyloid polypeptide

acts_upstream_of_or_within

(PMID:14970190)

PMID:14970190

NCBI chr 6:142,244,151...142,249,546
Ensembl chr 6:142,244,149...142,249,687

Ifna

interferon alpha

acts_upstream_of_or_within

(PMID:17442941)

interferon beta 1, fibroblast

acts_upstream_of_or_within

(PMID:17442941)

PMID:17442941

NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011

Ifng

interferon gamma

acts_upstream_of_or_within

(PMID:17442941)

PMID:17442941

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

Il4

interleukin 4

acts_upstream_of_or_within

(PMID:12941478), (PMID:17442941)

PMID:12941478 PMID:17442941

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

Inpp4b

inositol polyphosphate-4-phosphatase, type II

acts_upstream_of_or_within

IGI
IMP

(PMID:21982707)

PMID:21982707

NCBI chr 8:82,068,895...82,865,553
Ensembl chr 8:82,069,185...82,854,543

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(PMID:12161749)

PMID:12161749

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

GO_REF:0000119

NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

involved_in

GO_REF:0000119

NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799

Lrrc17

leucine rich repeat containing 17

involved_in

(PMID:19336404)

PMID:19336404

NCBI chr 5:21,748,525...21,780,909
Ensembl chr 5:21,748,557...21,780,902

Mafb

MAF bZIP transcription factor B

involved_in

(PMID:19440205)

PMID:19440205

NCBI chr 2:160,205,597...160,208,985
Ensembl chr 2:160,205,623...160,208,985

Nf1

neurofibromin 1

acts_upstream_of_or_within

(PMID:17053831)

PMID:17053831

NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438

Pias3

protein inhibitor of activated STAT 3

acts_upstream_of_or_within

IDA
IMP

(PMID:17442941)

PMID:17442941

NCBI chr 3:96,603,679...96,613,386
Ensembl chr 3:96,603,700...96,613,386

Pik3r1

phosphoinositide-3-kinase regulatory subunit 1

acts_upstream_of_or_within

(PMID:17053831)

PMID:17053831

NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725

Pilrb1

paired immunoglobin-like type 2 receptor beta 1

involved_in

(PMID:18802077)

PMID:18802077

NCBI chr 5:137,850,403...137,856,687
Ensembl chr 5:137,850,409...137,856,368

Pira1

paired-Ig-like receptor A1

involved_in

GO_REF:0000119

NCBI chr 7:3,734,625...3,742,957
Ensembl chr 7:3,734,629...3,742,888

Pira6

paired-Ig-like receptor A6

involved_in

GO_REF:0000119

Pirb

paired Ig-like receptor B

involved_in

(PMID:18802077)

PMID:18802077

NCBI chr 7:3,715,504...3,723,381
Ensembl chr 7:3,714,408...3,723,390

Sfrp1

secreted frizzled-related protein 1

involved_in
acts_upstream_of_or_within

PMID:14976225 PMID:17540629

(PMID:14976225)

RGD
GO_Central
MGI

GO_REF:0000096 RGD:4107086

NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648

Tcta

T cell leukemia translocation altered gene

involved_in

GO_REF:0000119

NCBI chr 9:108,180,157...108,183,174
Ensembl chr 9:108,180,157...108,183,359

Tmem178

transmembrane protein 178

involved_in

(PMID:26644563)

PMID:26644563

GO_REF:0000033

NCBI chr17:81,252,061...81,309,245
Ensembl chr17:81,252,061...81,309,245

Tnfaip6

tumor necrosis factor alpha induced protein 6

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698

Tnfrsf11b

tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

acts_upstream_of_or_within
involved_in

PMID:9168977 PMID:29415886

(PMID:29415886)
(PMID:9168977)

MGI
ComplexPortal

NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880

Tob2

transducer of ERBB2, 2

acts_upstream_of_or_within

(PMID:18358842)

PMID:18358842

NCBI chr15:81,732,471...81,744,742
Ensembl chr15:81,732,473...81,742,997

Ubash3b

ubiquitin associated and SH3 domain containing, B

acts_upstream_of_or_within

(PMID:23149425)

PMID:23149425

NCBI chr 9:40,922,056...41,069,358
Ensembl chr 9:40,922,394...41,072,993

negative regulation of plasma cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B cell leukemia/lymphoma 6

acts_upstream_of_or_within

(PMID:15240705)

PMID:15240705

NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

(PMID:24935931)

PMID:24935931

NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707

negative regulation of positive thymic T cell selection

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptpn2

protein tyrosine phosphatase, non-receptor type 2

involved_in

(PMID:22080863)

PMID:22080863

NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665

negative regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd44

CD44 antigen

involved_in

(PMID:25065622)

NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010

Ctla4

cytotoxic T-lymphocyte-associated protein 4

involved_in

IBA
ISO

GO_REF:0000033 GO_REF:0000119

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

Hspb1

heat shock protein 1

involved_in

PMID:30287503

GO_REF:0000096 RGD:38549580

NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417

interferon regulatory factor 1

involved_in

(PMID:18641303)

PMID:18641303

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

Lag3

lymphocyte-activation gene 3

involved_in

(PMID:15485628)

PMID:15485628

NCBI chr 6:124,881,322...124,888,668
Ensembl chr 6:124,881,324...124,888,668

Mdk

midkine

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642

Mir21a

microRNA 21a

involved_in

(PMID:22387553)

PMID:22387553

NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984

Mir30b

microRNA 30b

involved_in

(PMID:22387553)

PMID:22387553

NCBI chr15:68,209,264...68,209,359
Ensembl chr15:68,209,264...68,209,359

tumor necrosis factor (ligand) superfamily, member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

Tug1

taurine upregulated gene 1

NCBI chr11:3,589,313...3,599,021
Ensembl chr11:3,589,785...3,599,673

negative regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

acts_upstream_of_or_within

(PMID:7679955)

PMID:7679955

NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724

Dtx1

deltex 1, E3 ubiquitin ligase

acts_upstream_of_or_within

(PMID:12794108)

PMID:12794108

NCBI chr 5:120,818,268...120,850,879
Ensembl chr 5:120,818,267...120,849,992

Ifna2

interferon alpha 2

involved_in

(PMID:20554961)

PMID:20554961

NCBI chr 4:88,601,444...88,602,016
Ensembl chr 4:88,601,118...88,602,149

Ifnb1

interferon beta 1, fibroblast

involved_in

GO_REF:0000119

NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011

Nrarp

Notch-regulated ankyrin repeat protein

acts_upstream_of_or_within

(PMID:12794108)

PMID:12794108

NCBI chr 2:25,070,770...25,073,351
Ensembl chr 2:25,070,770...25,073,351

Prdx2

peroxiredoxin 2

acts_upstream_of_or_within

(PMID:16290204)

PMID:16290204

NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463

negative regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bmp4

bone morphogenetic protein 4

involved_in

GO_REF:0000119

NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126

Foxj1

forkhead box J1

involved_in

(PMID:16339515)

PMID:16339515

NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225

Indian hedgehog

involved_in

(PMID:19109233)

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

Nfkbid

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta

acts_upstream_of_or_within

(PMID:11931770)

PMID:11931770

NCBI chr 7:30,121,156...30,128,173
Ensembl chr 7:30,121,157...30,128,171

Rag2

recombination activating gene 2

involved_in

PMID:30206106

GO_REF:0000096 GO_REF:0000107 RGD:38508903

NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874

sonic hedgehog

acts_upstream_of_or_within

(PMID:10981962)

PMID:10981962

NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254

Zc3h8

zinc finger CCCH type containing 8

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 2:128,768,188...128,786,018
Ensembl chr 2:128,768,188...128,785,997

Zfp608

zinc finger protein 608

involved_in

(PMID:23076336)

PMID:23076336

NCBI chr18:55,021,117...55,125,690
Ensembl chr18:55,021,120...55,125,627

negative regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ascl2

achaete-scute family bHLH transcription factor 2

involved_in

(PMID:24463518)

PMID:24463518

NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001

Il4ra

interleukin 4 receptor, alpha

acts_upstream_of_or_within

(PMID:16424184)

NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646

Jak3

Janus kinase 3

involved_in

(PMID:16020505)

PMID:16020505

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

tumor necrosis factor (ligand) superfamily, member 4

involved_in

(PMID:9670042)

PMID:9670042

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

negative regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ascl2

achaete-scute family bHLH transcription factor 2

involved_in

(PMID:24463518)

PMID:24463518

NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001

forkhead box P3

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

interleukin 2

involved_in

(PMID:25642768)

PMID:25642768

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

Il4

interleukin 4

acts_upstream_of_or_within

(PMID:18792410)

PMID:18792410

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

Pf4

platelet factor 4

involved_in

RGD
GO_Central
Ensembl

PMID:24986443

GO_REF:0000096 GO_REF:0000107 RGD:329901907

NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242

Rc3h1

RING CCCH (C3H) domains 1

involved_in

(PMID:25282160)

NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548

Rc3h2

ring finger and CCCH-type zinc finger domains 2

involved_in

(PMID:25282160)

NCBI chr 2:37,260,078...37,313,007
Ensembl chr 2:37,260,081...37,312,915

Smad7

SMAD family member 7

involved_in

(PMID:25642768)

PMID:25642768

NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006

Tbx21

T-box 21

involved_in

(PMID:21151104)

PMID:21151104

NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

(PMID:23034280)

PMID:23034280

NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083

Zc3h12a

zinc finger CCCH type containing 12A

involved_in

(PMID:25282160)

NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633

negative regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd69

CD69 antigen

involved_in

IEA

Ensembl

GO_REF:0000107

NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399

Jak3

Janus kinase 3

involved_in

(PMID:20696842)

PMID:20696842

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

Lgals1

lectin, galactose binding, soluble 1

involved_in

IEA

Ensembl

GO_REF:0000107

NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665

Loxl3

lysyl oxidase-like 3

involved_in

(PMID:28065600)

PMID:28065600

GO_REF:0000119

NCBI chr 6:83,011,186...83,029,547
Ensembl chr 6:83,011,154...83,029,543

signal transducer and activator of transcription 5A

involved_in

(PMID:20696842)

PMID:20696842

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

Tbx21

T-box 21

involved_in

(PMID:21151104)

PMID:21151104

NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157

Tnfsf18

tumor necrosis factor (ligand) superfamily, member 18

involved_in

(PMID:24107315)

PMID:24107315

NCBI chr 1:161,322,221...161,333,903
Ensembl chr 1:161,322,224...161,332,859

negative regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anxa1

annexin A1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308

Ascl2

achaete-scute family bHLH transcription factor 2

involved_in

(PMID:24463518)

PMID:24463518

NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001

B cell leukemia/lymphoma 6

acts_upstream_of_or_within

(PMID:12594267)

PMID:12594267

NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602

Hlx

H2.0-like homeobox

acts_upstream_of_or_within

(PMID:16424184)

NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816

interferon regulatory factor 1

involved_in

(PMID:11244049)

PMID:11244049

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

Socs5

suppressor of cytokine signaling 5

involved_in

(PMID:12242343)

PMID:12242343

NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267

Zfp35

zinc finger protein 35

acts_upstream_of_or_within

(PMID:19783676)

PMID:19783676

NCBI chr18:24,122,134...24,138,428
Ensembl chr18:24,122,689...24,138,433

negative regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Rc3h1

RING CCCH (C3H) domains 1

acts_upstream_of_or_within

(PMID:15917799)

PMID:15917799

NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548

positive regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

(PMID:11067867), (PMID:16670300)
(PMID:11067867), (PMID:12163459), (PMID:16670300)

PMID:11067867 PMID:12163459 PMID:16670300

NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159

Gli3

GLI-Kruppel family member GLI3

involved_in

(PMID:15855276)

PMID:15855276

NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611

Indian hedgehog

involved_in

(PMID:19109233)

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

Itpkb

inositol 1,4,5-trisphosphate 3-kinase B

acts_upstream_of_or_within

(PMID:15064401)

PMID:15064401

NCBI chr 1:180,156,655...180,252,367
Ensembl chr 1:180,158,050...180,252,367

Nkap

NFKB activating protein

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr X:36,390,416...36,414,399
Ensembl chr X:36,390,448...36,414,399

Pnp

purine-nucleoside phosphorylase

acts_upstream_of_or_within

(PMID:10859343), (PMID:16964310)
(PMID:9122228)

PMID:9122228 PMID:10859343 PMID:16964310

GO_REF:0000008

NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869

Pnp2

purine-nucleoside phosphorylase 2

acts_upstream_of_or_within

(PMID:16964310)

PMID:16964310

NCBI chr14:51,193,598...51,202,206
Ensembl chr14:51,193,449...51,202,206

Rhoa

ras homolog family member A

involved_in

(PMID:25398325)

PMID:25398325

NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133

sonic hedgehog

involved_in

(PMID:14764698)

PMID:14764698

NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254

Syk

spleen tyrosine kinase

acts_upstream_of_or_within

(PMID:9275205)

PMID:9275205

NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828

Zap70

zeta-chain (TCR) associated protein kinase

acts_upstream_of_or_within

(PMID:9208839)
(PMID:7630421)
(PMID:9275205)

PMID:7630421 PMID:9208839 PMID:9275205

NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899

positive regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atp11c

ATPase, class VI, type 11C

involved_in

(PMID:21423173)

PMID:21423173

NCBI chr X:59,268,643...59,450,041
Ensembl chr X:59,268,650...59,636,304

Bad

BCL2-associated agonist of cell death

acts_upstream_of_or_within

(PMID:12431371)

PMID:12431371

NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267

Cd27

CD27 antigen

involved_in

IEA

InterPro

GO_REF:0000002

NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973

Il21

interleukin 21

involved_in

(PMID:15494482)

PMID:15494482

NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785

Il2rg

interleukin 2 receptor, gamma chain

acts_upstream_of_or_within

(PMID:9252128)
(PMID:23918385)

PMID:9252128 PMID:23918385

NCBI chr X:100,307,991...100,311,861
Ensembl chr X:100,307,984...100,311,861

Il7

interleukin 7

acts_upstream_of_or_within

(PMID:16797412)

PMID:16797412

NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

(PMID:10704460), (PMID:9620849)

PMID:9620849 PMID:10704460

GO_REF:0000033

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

Mmp14

matrix metallopeptidase 14 (membrane-inserted)

involved_in

(PMID:21572390)

PMID:21572390

NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821

NCK associated protein 1 like

involved_in

(PMID:19015308)

NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237

Pcid2

PCI domain containing 2

involved_in

(PMID:20870947)

PMID:20870947

NCBI chr 8:13,125,476...13,155,343
Ensembl chr 8:13,127,189...13,155,459

Pnp

purine-nucleoside phosphorylase

acts_upstream_of_or_within

(PMID:10859343)

PMID:10859343

NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869

Ppp2r3c

protein phosphatase 2, regulatory subunit B'', gamma

acts_upstream_of_or_within
involved_in

IMP
IBA

(PMID:16129705)

PMID:16129705

GO_REF:0000033

NCBI chr12:55,327,594...55,350,024
Ensembl chr12:55,325,776...55,349,783

Spi1

Spi-1 proto-oncogene

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

(PMID:10979977)

PMID:10979977

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

(PMID:10979977)

PMID:10979977

NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550

Syk

spleen tyrosine kinase

acts_upstream_of_or_within
involved_in

(PMID:7477353)
(PMID:7477352)

PMID:7477352 PMID:7477353

GO_REF:0000119

NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828

Xbp1

X-box binding protein 1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893

positive regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd83

CD83 antigen

acts_upstream_of_or_within

(PMID:15322158)

PMID:15322158

NCBI chr13:43,938,661...43,956,608
Ensembl chr13:43,938,251...43,956,608

forkhead box P3

acts_upstream_of_or_within

(PMID:17028180)

PMID:17028180

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

NCK associated protein 1 like

involved_in

(PMID:19015308)

NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237

Sash3

SAM and SH3 domain containing 3

acts_upstream_of_or_within

(PMID:16227612)

PMID:16227612

NCBI chr X:47,235,313...47,250,442
Ensembl chr X:47,235,313...47,250,442

Socs1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400

tumor necrosis factor (ligand) superfamily, member 4

involved_in

(PMID:20639485)

PMID:20639485

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

zinc finger and BTB domain containing 7B

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PMID:12612578 PMID:16275384 PMID:16301745 PMID:18368049 PMID:18573908

forkhead box P3

acts_upstream_of_or_within
involved_in

IMP
TAS

(PMID:16275384)
(PMID:18368049)
(PMID:16301745), (PMID:18573908)
(PMID:12612578)

MGI
UniProt

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

Gimap3

GTPase, IMAP family member 3

involved_in

GO_REF:0000096

NCBI chr 6:48,741,398...48,747,785
Ensembl chr 6:48,741,398...48,747,785

Gimap5

GTPase, IMAP family member 5

involved_in

PMID:15778366

GO_REF:0000096 RGD:2303772

NCBI chr 6:48,723,131...48,731,134
Ensembl chr 6:48,723,131...48,731,144

H2-Ea

histocompatibility 2, class II antigen E alpha

involved_in

GO_REF:0000119

NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618

histocompatibility 2, class II antigen E beta

involved_in

(PMID:28467828)

PMID:28467828

NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648

Il2rg

interleukin 2 receptor, gamma chain

acts_upstream_of_or_within

(PMID:16227984)

PMID:16227984

NCBI chr X:100,307,991...100,311,861
Ensembl chr X:100,307,984...100,311,861

Klhl25

kelch-like 25

involved_in

IDA
ISO

(PMID:34491895)

PMID:34491895

GO_REF:0000119

NCBI chr 7:75,498,086...75,523,881
Ensembl chr 7:75,498,058...75,523,879

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ifng

interferon gamma

involved_in

GO_REF:0000119

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

lectin, galactose binding, soluble 9

involved_in

(PMID:20209097)

PMID:20209097

NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772

positive regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cbfb

core binding factor beta

involved_in

(PMID:18258917)

NCBI chr 8:105,897,306...105,944,621
Ensembl chr 8:105,897,306...105,944,621

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

GO_REF:0000119

NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

involved_in

GO_REF:0000119

NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799

NCK associated protein 1 like

involved_in

(PMID:19015308)

NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237

runt related transcription factor 1

involved_in

(PMID:18258917)

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

Runx3

runt related transcription factor 3

involved_in

(PMID:18258917)

NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301

positive regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hsp90aa1

heat shock protein 90, alpha (cytosolic), class A member 1

involved_in

(PMID:12855682)

PMID:12855682

NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162

Sart1

squamous cell carcinoma antigen recognized by T cells 1

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr19:5,427,551...5,438,731
Ensembl chr19:5,427,551...5,438,731

Tnfsf9

tumor necrosis factor (ligand) superfamily, member 9

involved_in

ISO
IEA
IBA

PMID:19187795

GO_REF:0000033 GO_REF:0000096 GO_REF:0000107 RGD:2317344

NCBI chr17:57,412,113...57,414,757
Ensembl chr17:57,412,325...57,414,757

positive regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ager

advanced glycosylation end product-specific receptor

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910

Cd40lg

CD40 ligand

involved_in

PMID:18384807

GO_REF:0000096 RGD:2313415

NCBI chr X:56,257,448...56,269,402
Ensembl chr X:56,257,503...56,269,402

Hmgb1

high mobility group box 1

involved_in

GO_REF:0000119

NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299

Lgals1

lectin, galactose binding, soluble 1

NOT|involved_in

(PMID:16116184)

PMID:16116184

NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665

Lgals3

lectin, galactose binding, soluble 3

NOT|involved_in

(PMID:16116184)

PMID:16116184

NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617

lectin, galactose binding, soluble 9

involved_in

(PMID:16116184)

PMID:16116184

NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

(PMID:22615127)

NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219

positive regulation of eosinophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il5

interleukin 5

involved_in

PMID:10529595 PMID:10727846

GO_REF:0000096 GO_REF:0000107 RGD:2303509 RGD:2303750

NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933

Trib1

tribbles pseudokinase 1

involved_in

(PMID:23515163)

PMID:23515163

NCBI chr15:59,520,503...59,528,948
Ensembl chr15:59,520,199...59,528,948

positive regulation of gamma-delta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gimap3

GTPase, IMAP family member 3

involved_in

GO_REF:0000096

NCBI chr 6:48,741,398...48,747,785
Ensembl chr 6:48,741,398...48,747,785

Gimap5

GTPase, IMAP family member 5

involved_in

PMID:11859104

GO_REF:0000096 RGD:625608

NCBI chr 6:48,723,131...48,731,134
Ensembl chr 6:48,723,131...48,731,144

Lck

lymphocyte protein tyrosine kinase

acts_upstream_of_or_within

(PMID:7807014)

PMID:7807014

NCBI chr 4:129,442,142...129,467,415
Ensembl chr 4:129,442,137...129,467,434

Lef1

lymphoid enhancer binding factor 1

involved_in

(PMID:23562159)

NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005

NCK associated protein 1 like

involved_in

(PMID:19015308)

NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237

Ptprc

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

(PMID:7807014)

PMID:7807014

NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446

Skint1

selection and upkeep of intraepithelial T cells 1

acts_upstream_of_or_within

(PMID:21300860)

PMID:21300860

NCBI chr 4:111,863,466...111,886,735
Ensembl chr 4:111,863,466...111,886,735

Sox13

SRY (sex determining region Y)-box 13

involved_in

(PMID:23562159)

NCBI chr 1:133,310,038...133,352,159
Ensembl chr 1:133,310,041...133,352,115

Sox4

SRY (sex determining region Y)-box 4

involved_in

(PMID:23562159)

NCBI chr13:29,132,902...29,137,682
Ensembl chr13:29,132,902...29,137,696

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

(PMID:15294943)

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

(PMID:15294943)

NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550

Syk

spleen tyrosine kinase

acts_upstream_of_or_within

(PMID:7477352)
(PMID:8790395)

PMID:7477352 PMID:8790395

NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828

positive regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Evi2

ecotropic viral integration site 2

involved_in

GO_REF:0000119

NCBI chr11:79,404,211...79,421,435
Ensembl chr11:79,405,882...79,414,588
Ensembl chr11:79,405,882...79,414,588

Evi2b

ecotropic viral integration site 2b

involved_in

ISO
ISS
IMP

(PMID:28186500)

PMID:28186500

GO_REF:0000024 GO_REF:0000119

NCBI chr11:79,404,211...79,414,588
Ensembl chr11:79,405,882...79,414,588

Gfi1b

growth factor independent 1B

involved_in

(PMID:17707228)

PMID:17707228

NCBI chr 2:28,499,462...28,511,994
Ensembl chr 2:28,499,462...28,511,994

Hax1

HCLS1 associated X-1

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 3:89,902,753...89,906,023
Ensembl chr 3:89,902,753...89,906,087

Hcls1

hematopoietic cell specific Lyn substrate 1

involved_in

(PMID:23001182)

GO_Central
BHF-UCL

PMID:23001182

GO_REF:0000119

NCBI chr16:36,755,345...36,783,576
Ensembl chr16:36,755,345...36,783,574

Lef1

lymphoid enhancer binding factor 1

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005

Mir223

microRNA 223

acts_upstream_of_or_within

(PMID:18278031)

PMID:18278031

NCBI chr X:95,286,423...95,286,532
Ensembl chr X:95,286,423...95,286,532

Mir3107

microRNA 3107

involved_in

(PMID:25857263)

NCBI chr 8:23,632,589...23,632,678
Ensembl chr 8:23,632,589...23,632,678

Mir486

microRNA 486

involved_in

(PMID:25857263)

NCBI chr 8:23,632,571...23,632,698
Ensembl chr 8:23,632,571...23,632,698

runt related transcription factor 1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

Tesc

tescalcin

involved_in

IBA
ISO
ISS

GO_REF:0000024 GO_REF:0000033 GO_REF:0000119

NCBI chr 5:118,165,808...118,199,943
Ensembl chr 5:118,165,808...118,199,943

Tescl

tescalcin-like

involved_in

IBA
ISO

GO_REF:0000033 GO_REF:0000119

NCBI chr 7:24,032,505...24,033,390
Ensembl chr 7:24,032,507...24,033,361

positive regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(PMID:9620849)

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

NCK associated protein 1 like

involved_in

(PMID:19015308)

NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237

Prkdc

protein kinase, DNA activated, catalytic polypeptide

involved_in

(PMID:32103174)

PMID:32103174

NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

(PMID:15294943)

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

(PMID:15294943)

NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550

Xrcc6

X-ray repair complementing defective repair in Chinese hamster cells 6

involved_in

(PMID:32103174)

PMID:32103174

NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286

positive regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Asxl2

ASXL transcriptional regulator 2

acts_upstream_of_or_within

(PMID:21490954)

PMID:21490954

NCBI chr12:3,476,892...3,560,811
Ensembl chr12:3,476,857...3,556,852

Calca

calcitonin/calcitonin-related polypeptide, alpha

involved_in

(PMID:10822112)

PMID:10822112

NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592

Casp8

caspase 8

involved_in

GO_REF:0000119

NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662

Csf1

colony stimulating factor 1 (macrophage)

acts_upstream_of_or_within
involved_in

IMP
ISO
IBA

(PMID:9215625)

PMID:9215625

GO_REF:0000033 GO_REF:0000119

NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785

Fadd

Fas associated via death domain

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200

Hcls1

hematopoietic cell specific Lyn substrate 1

involved_in

(PMID:23001182)

PMID:23001182

NCBI chr16:36,755,345...36,783,576
Ensembl chr16:36,755,345...36,783,574

Hsf1

heat shock factor 1

involved_in

GO_REF:0000119

NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113

Id2

inhibitor of DNA binding 2

acts_upstream_of_or_within

(PMID:15616565)

PMID:15616565

NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139

Il34

interleukin 34

involved_in

IBA
IEA
ISO

GO_REF:0000033 GO_REF:0000107 GO_REF:0000119

NCBI chr 8:111,467,809...111,532,579
Ensembl chr 8:111,468,461...111,532,556

Lif

leukemia inhibitory factor

acts_upstream_of_or_within

GO_REF:0000008

NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514

Mir145a

microRNA 145a

acts_upstream_of

(PMID:30634164)

PMID:30634164

NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965

Pf4

platelet factor 4

involved_in

(PMID:10666185)

PMID:10666185

NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242

Prkca

protein kinase C, alpha

involved_in

(PMID:9508782)

PMID:9508782

NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754

Rb1

RB transcriptional corepressor 1

acts_upstream_of_or_within

(PMID:15616565)

PMID:15616565

NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262

Ripk1

receptor (TNFRSF)-interacting serine-threonine kinase 1

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130

Ror2

receptor tyrosine kinase-like orphan receptor 2

involved_in

PMID:25749876

GO_REF:0000096 RGD:11537353

NCBI chr13:53,263,353...53,440,160
Ensembl chr13:53,263,348...53,440,160

Trib1

tribbles pseudokinase 1

involved_in

(PMID:23515163)

PMID:23515163

NCBI chr15:59,520,503...59,528,948
Ensembl chr15:59,520,199...59,528,948

positive regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Itgam

integrin alpha M

involved_in

(PMID:9862668)

PMID:9862668

NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663

Pla2g3

phospholipase A2, group III

involved_in

(PMID:23624557)

PMID:23624557

NCBI chr11:3,438,158...3,449,346
Ensembl chr11:3,438,284...3,449,350

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

(PMID:15947484)

PMID:15947484

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

positive regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd46

CD46 antigen, complement regulatory protein

involved_in

GO_REF:0000119

NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557

H2-Ea

histocompatibility 2, class II antigen E alpha

involved_in

GO_REF:0000119

NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618

histocompatibility 2, class II antigen E beta

involved_in

(PMID:27591323)

PMID:27591323

NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648

Il23a

interleukin 23, alpha subunit p19

involved_in

(PMID:14688363)

PMID:14688363

NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621

Pck1

phosphoenolpyruvate carboxykinase 1, cytosolic

involved_in

(PMID:29230018)

PMID:29230018

NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066

tumor necrosis factor (ligand) superfamily, member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

positive regulation of microglia differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

transforming growth factor, beta 1

involved_in

(PMID:29909984)

PMID:29909984

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

positive regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Acin1

apoptotic chromatin condensation inducer 1

involved_in

GO_REF:0000024

NCBI chr14:54,879,618...54,924,422
Ensembl chr14:54,879,618...54,924,388

Cd4

CD4 antigen

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184

Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724

Csf1

colony stimulating factor 1 (macrophage)

acts_upstream_of_or_within

(PMID:9215625)

PMID:9215625

NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785

Ctnnbip1

catenin beta interacting protein 1

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 4:149,602,698...149,650,894
Ensembl chr 4:149,602,693...149,650,894

Dcstamp

dendrocyte expressed seven transmembrane protein

involved_in

(PMID:17713547)

PMID:17713547

NCBI chr15:39,609,326...39,624,334
Ensembl chr15:39,609,326...39,624,334

Fes

feline sarcoma oncogene

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 7:80,027,506...80,037,702
Ensembl chr 7:80,027,504...80,037,694

histocompatibility 2, class II antigen E beta

involved_in

(PMID:24942581)

CAFA

PMID:24942581

NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648

Il34

interleukin 34

involved_in

IBA
IEA
ISO

GO_REF:0000033 GO_REF:0000107 GO_REF:0000119

NCBI chr 8:111,467,809...111,532,579
Ensembl chr 8:111,468,461...111,532,556

Jun

jun proto-oncogene

involved_in

murine WEHI-3B D+ cells with or without retinoic acid

PMID:7947389

GO_REF:0000096 RGD:2291846

NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459

Zfp36l1

zinc finger protein 36, C3H type-like 1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787

positive regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd101

CD101 antigen

acts_upstream_of_or_within

(PMID:21613616)

PMID:21613616

NCBI chr 3:100,899,505...100,936,869
Ensembl chr 3:100,900,845...100,936,872

Il3

interleukin 3

acts_upstream_of_or_within

(PMID:1375116), (PMID:7690439)

PMID:1375116 PMID:7690439

NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103

Kitl

kit ligand

acts_upstream_of_or_within

(PMID:1375116), (PMID:7690439)

PMID:1375116 PMID:7690439

NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278

positive regulation of natural killer cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Axl

AXL receptor tyrosine kinase

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130

Flt3l

FMS-like tyrosine kinase 3 ligand

acts_upstream_of_or_within

(PMID:14607906)

PMID:14607906

NCBI chr 7:44,780,607...44,785,914
Ensembl chr 7:44,779,212...44,785,856

Gas6

growth arrest specific 6

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490

Il15

interleukin 15

acts_upstream_of_or_within

IDA
IMP
IGI

(PMID:14607906)
(PMID:17318811)

PMID:14607906 PMID:17318811

NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851

Il15ra

interleukin 15 receptor, alpha chain

acts_upstream_of_or_within

(PMID:14607906)

PMID:14607906

NCBI chr 2:11,709,992...11,739,129
Ensembl chr 2:11,710,101...11,739,128

Il21

interleukin 21

acts_upstream_of_or_within

(PMID:14764669)

PMID:14764669

NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785

interferon regulatory factor 1

involved_in

(PMID:11244049)

PMID:11244049

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

Rasgrp1

RAS guanyl releasing protein 1

involved_in

(PMID:21957144)

PMID:21957144

NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

(PMID:9841920)

PMID:9841920

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

(PMID:9841920)

PMID:9841920

NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550

Tox

thymocyte selection-associated high mobility group box

acts_upstream_of_or_within

(PMID:20818394)

PMID:20818394

NCBI chr 4:6,686,353...6,991,557
Ensembl chr 4:6,686,353...6,991,557

Zbtb1

zinc finger and BTB domain containing 1

involved_in

(PMID:22753936)

PMID:22753936

NCBI chr12:76,416,825...76,443,729
Ensembl chr12:76,417,040...76,443,724

positive regulation of neutrophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Evi2b

ecotropic viral integration site 2b

involved_in

(PMID:28186500)

PMID:28186500

GO_REF:0000033

NCBI chr11:79,404,211...79,414,588
Ensembl chr11:79,405,882...79,414,588

Ikzf1

IKAROS family zinc finger 1

acts_upstream_of_or_within

(PMID:12406904)

PMID:12406904

NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926

positive regulation of NK T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ap3b1

adaptor-related protein complex 3, beta 1 subunit

acts_upstream_of_or_within

(PMID:14557411)

PMID:14557411

NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825

Ap3d1

adaptor-related protein complex 3, delta 1 subunit

acts_upstream_of_or_within

(PMID:14557411)

PMID:14557411

NCBI chr10:80,542,790...80,578,137
Ensembl chr10:80,542,790...80,578,098

Cd1d1

CD1d1 antigen

acts_upstream_of_or_within

(PMID:9133426)
(PMID:10201995)

PMID:9133426 PMID:10201995

NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748

Tgfbr2

transforming growth factor, beta receptor II

acts_upstream_of_or_within

(PMID:16973387)

PMID:16973387

NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428

positive regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gpr68

G protein-coupled receptor 68

acts_upstream_of_or_within

(PMID:19479052)

PMID:19479052

NCBI chr12:100,842,941...100,874,457
Ensembl chr12:100,842,941...100,874,457

Ninj1

ninjurin 1

involved_in

(PMID:30700695)

PMID:30700695

NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720

Slc9b2

solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2

acts_upstream_of_or_within

(PMID:18269914)

PMID:18269914

NCBI chr 3:135,013,083...135,048,606
Ensembl chr 3:135,013,461...135,051,148

Tnfsf11

tumor necrosis factor (ligand) superfamily, member 11

acts_upstream_of_or_within

(PMID:18269914), (PMID:22437732), (PMID:23980096)

PMID:18269914 PMID:22437732 PMID:23980096

NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483

Tyrobp

TYRO protein tyrosine kinase binding protein

involved_in

(PMID:14969392)

PMID:14969392

NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010

positive regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Asxl2

ASXL transcriptional regulator 2

acts_upstream_of_or_within

(PMID:21490954)

PMID:21490954

NCBI chr12:3,476,892...3,560,811
Ensembl chr12:3,476,857...3,556,852

Car2

carbonic anhydrase 2

involved_in

PMID:10523502

GO_REF:0000096 RGD:1600711

NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830

Ccl3

C-C motif chemokine ligand 3

involved_in

PMID:9920817

GO_REF:0000096 GO_REF:0000107 RGD:2303108

NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181

Ccl5

C-C motif chemokine ligand 5

involved_in

PMID:9920817

GO_REF:0000096 RGD:2303108

NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344

Ccl6

C-C motif chemokine ligand 6

NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913

Ccl9

C-C motif chemokine ligand 9

involved_in

GO_REF:0000096

NCBI chr11:83,463,743...83,469,462
Ensembl chr11:83,463,745...83,469,462

Ccr1

C-C motif chemokine receptor 1

involved_in

GO_REF:0000119

NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729

Ccr1l1

C-C motif chemokine receptor 1 like 1

involved_in

GO_REF:0000119

NCBI chr 9:123,776,467...123,786,752
Ensembl chr 9:123,777,280...123,778,445

Creb1

cAMP responsive element binding protein 1

acts_upstream_of_or_within

(PMID:23395171)

PMID:23395171

NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707

Csf1

colony stimulating factor 1 (macrophage)

acts_upstream_of_or_within
involved_in

IMP
ISO
IDA
IGI

(PMID:9215625)
(PMID:15657444)
(PMID:17053831), (PMID:21048959)

PMID:9215625 PMID:15657444 PMID:17053831 PMID:21048959

GO_REF:0000119

NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785

Csf1r

colony stimulating factor 1 receptor

involved_in

PMID:17121910

GO_REF:0000096 RGD:2293713

NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221

Dlk1

delta like non-canonical Notch ligand 1

involved_in

GO_REF:0000008

NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262

Eeig1

estrogen-induced osteoclastogenesis regulator 1

involved_in

(PMID:23478294), (PMID:32741026)

PMID:23478294 PMID:32741026

NCBI chr 2:32,425,344...32,459,763
Ensembl chr 2:32,425,344...32,459,768

Fos

FBJ osteosarcoma oncogene

acts_upstream_of_or_within

(PMID:23395171)

PMID:23395171

NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047

Gnas

GNAS complex locus

acts_upstream_of_or_within

(PMID:15797856)

PMID:15797856

NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537

Gsk3b

glycogen synthase kinase 3 beta

involved_in

PMID:28731198

GO_REF:0000096 RGD:13792731

NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446

Ifng

interferon gamma

involved_in

GO_REF:0000119

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

Il12b

interleukin 12b

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860

Il17a

interleukin 17A

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720

Il20

interleukin 20

acts_upstream_of_or_within

(PMID:21844205)

PMID:21844205

NCBI chr 1:130,834,722...130,839,033
Ensembl chr 1:130,834,722...130,839,188

Il23a

interleukin 23, alpha subunit p19

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621

Itgb3

integrin beta 3

involved_in

(PMID:16995821)

PMID:16995821

NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302

Klf10

Kruppel-like transcription factor 10

acts_upstream_of_or_within

(PMID:15657444)

PMID:15657444

NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950

Nedd9

neural precursor cell expressed, developmentally down-regulated gene 9

involved_in

(PMID:27336669)

PMID:27336669

NCBI chr13:41,463,392...41,640,836
Ensembl chr13:41,463,057...41,640,838

Notch2

notch 2

involved_in

(PMID:18710934)

PMID:18710934

NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677

Ocstamp

osteoclast stimulatory transmembrane protein

involved_in

(PMID:18064667)

PMID:18064667

NCBI chr 2:165,237,370...165,242,314
Ensembl chr 2:165,235,680...165,242,325

Pou4f1

POU domain, class 4, transcription factor 1

involved_in

(PMID:17668438)

PMID:17668438

NCBI chr14:104,699,111...104,705,554
Ensembl chr14:104,699,112...104,705,435

Pou4f2

POU domain, class 4, transcription factor 2

involved_in

(PMID:17668438)

PMID:17668438

NCBI chr 8:79,159,638...79,163,276
Ensembl chr 8:79,159,639...79,163,274

Ppargc1b

peroxisome proliferative activated receptor, gamma, coactivator 1 beta

involved_in

(PMID:19252502)

DFLAT

PMID:19252502

NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502

Ppp3ca

protein phosphatase 3, catalytic subunit, alpha isoform

involved_in

(PMID:16968888)

PMID:16968888

NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488

Rptor

regulatory associated protein of MTOR, complex 1

involved_in

(PMID:27879318)

PMID:27879318

NCBI chr11:119,493,731...119,790,417
Ensembl chr11:119,493,731...119,790,402

Tm4sf19

transmembrane 4 L six family member 19

involved_in

(PMID:38016540)

PMID:38016540

NCBI chr16:32,218,823...32,227,397
Ensembl chr16:32,219,324...32,227,045

Tmem64

transmembrane protein 64

involved_in
acts_upstream_of_or_within

(PMID:23395171)

PMID:23395171

GO_REF:0000033

NCBI chr 4:15,265,820...15,286,753
Ensembl chr 4:15,265,831...15,286,753

Tnf

tumor necrosis factor

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

Tnfrsf11a

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

involved_in

(PMID:23478294)

PMID:23478294

NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709

Tnfsf11

tumor necrosis factor (ligand) superfamily, member 11

involved_in
acts_upstream_of_or_within

ISO
IBA
IMP
IGI
IDA

(PMID:23478294)
(PMID:17053831), (PMID:21048959)
(PMID:21982707)
(PMID:15657444), (PMID:15724149)

RGD
GO_Central
UniProt
MGI

PMID:11092398 PMID:15657444 PMID:15724149 PMID:17053831 PMID:21048959 More...

GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:730134

NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483

Traf6

TNF receptor-associated factor 6

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014

Trem2

triggering receptor expressed on myeloid cells 2

involved_in

(PMID:16418779)

PMID:16418779

NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175

positive regulation of plasma cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ddrgk1

DDRGK domain containing 1

involved_in

(PMID:30842412)

PMID:30842412

NCBI chr 2:130,495,955...130,506,549
Ensembl chr 2:130,495,880...130,506,579

Il10

interleukin 10

involved_in
acts_upstream_of

GO_REF:0000107 GO_REF:0000119

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

interleukin 2

involved_in
acts_upstream_of

GO_REF:0000107 GO_REF:0000119

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

Xbp1

X-box binding protein 1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893

positive regulation of pro-T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Zbtb1

zinc finger and BTB domain containing 1

involved_in

(PMID:22753936)

PMID:22753936

NCBI chr12:76,416,825...76,443,729
Ensembl chr12:76,417,040...76,443,724

positive regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ambra1

autophagy/beclin 1 regulator 1

involved_in

(PMID:30513302)

PMID:30513302

GO_REF:0000119

NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194

B cell leukemia/lymphoma 6

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602

Btn2a2

butyrophilin, subfamily 2, member A2

acts_upstream_of_or_within

(PMID:23589618)

PMID:23589618

NCBI chr13:23,661,219...23,673,028
Ensembl chr13:23,661,846...23,673,027

Carmil2

capping protein regulator and myosin 1 linker 2

acts_upstream_of_or_within

(PMID:23793062)

PMID:23793062

NCBI chr 8:106,412,642...106,424,827
Ensembl chr 8:106,412,906...106,424,819

Cd46

CD46 antigen, complement regulatory protein

involved_in

GO_REF:0000119

NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557

Dusp10

dual specificity phosphatase 10

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 1:183,766,575...183,807,833
Ensembl chr 1:183,745,499...183,807,833

Foxo3

forkhead box O3

involved_in

GO_REF:0000024

NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751

forkhead box P3

acts_upstream_of_or_within
involved_in

IDA
ISO
IMP

(PMID:12522256), (PMID:15100250), (PMID:16769892), (PMID:17028180)
(PMID:15780990)

PMID:12522256 PMID:15100250 PMID:15780990 PMID:16769892 PMID:17028180

GO_REF:0000119

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

H2-M3

histocompatibility 2, M region locus 3

involved_in

GO_REF:0000119

NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375

interleukin 2

involved_in

PMID:6233372

GO_REF:0000096 RGD:1600097

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

Il4i1

interleukin 4 induced 1

involved_in

IDA
ISO

(PMID:25778793)

PMID:25778793

GO_REF:0000119

NCBI chr 7:44,485,712...44,490,233
Ensembl chr 7:44,465,811...44,490,233

Il4i1b

interleukin 4 induced 1B

involved_in

GO_REF:0000119

NCBI chr 7:44,465,794...44,490,228
Ensembl chr 7:44,465,811...44,490,233

Kat5

K(lysine) acetyltransferase 5

involved_in

(PMID:24835996)

PMID:24835996

GO_REF:0000119

NCBI chr19:5,653,042...5,661,584
Ensembl chr19:5,653,042...5,660,265

lectin, galactose binding, soluble 9

involved_in

(PMID:25065622)

NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

GO_REF:0000119

NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

involved_in

GO_REF:0000119

NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799

microRNA 214

NCBI chr 1:162,050,937...162,051,046
Ensembl chr 1:162,050,937...162,051,046

Socs1

suppressor of cytokine signaling 1

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400

Sox12

SRY (sex determining region Y)-box 12

involved_in

(PMID:30190287)

PMID:30190287

NCBI chr 2:152,235,531...152,239,966
Ensembl chr 2:152,235,531...152,239,983

transforming growth factor, beta 1

involved_in

(PMID:25065622)

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

Vsir

V-set immunoregulatory receptor

involved_in

GO_REF:0000119

NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463

positive regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Actb

actin, beta

involved_in

(PMID:12110891)

NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509

Actl6a

actin-like 6A

involved_in

(PMID:12110891)

NCBI chr 3:32,762,695...32,781,122
Ensembl chr 3:32,760,447...32,781,122

Actl6b

actin-like 6B

involved_in

(PMID:12110891)

NCBI chr 5:137,551,784...137,567,844
Ensembl chr 5:137,551,779...137,567,844

adenosine deaminase

acts_upstream_of_or_within

(PMID:7731963)
(PMID:9478961)

PMID:7731963 PMID:9478961

NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159

Arid1a

AT-rich interaction domain 1A

involved_in

(PMID:12110891)

NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080

Arid2

AT-rich interaction domain 2

involved_in

(PMID:12110891)

NCBI chr15:96,185,403...96,303,344
Ensembl chr15:96,185,399...96,302,873

Bad

BCL2-associated agonist of cell death

acts_upstream_of_or_within

(PMID:12431371)

PMID:12431371

NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267

Brd7

bromodomain containing 7

involved_in

(PMID:12110891)

NCBI chr 8:89,056,522...89,089,249
Ensembl chr 8:89,057,667...89,088,822

Cd27

CD27 antigen

involved_in

(PMID:11728341)

PMID:11728341

NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973

Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

acts_upstream_of_or_within

(PMID:9432982)
(PMID:7679955), (PMID:8598040)

PMID:7679955 PMID:8598040 PMID:9432982

NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724

Cyld

CYLD lysine 63 deubiquitinase

acts_upstream_of_or_within

(PMID:16501569)

PMID:16501569

NCBI chr 8:89,423,506...89,478,574
Ensembl chr 8:89,423,675...89,478,573

Gata3

GATA binding protein 3

involved_in

(PMID:20696860)

PMID:20696860

NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845

H2-Aa

histocompatibility 2, class II antigen A, alpha

acts_upstream_of_or_within

(PMID:8598041)

PMID:8598041

NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797

H2-DMa

histocompatibility 2, class II, locus DMa

acts_upstream_of_or_within

(PMID:8598041), (PMID:9432982)
(PMID:8598040)
(PMID:8638109)

PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982

NCBI chr17:34,338,667...34,358,075
Ensembl chr17:34,338,515...34,358,075

Il12a

interleukin 12a

acts_upstream_of_or_within

(PMID:22968459)

PMID:22968459

NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880

Il1rl2

interleukin 1 receptor-like 2

acts_upstream_of_or_within

(PMID:22968459)

PMID:22968459

NCBI chr 1:40,363,697...40,406,722
Ensembl chr 1:40,363,770...40,406,722

interleukin 2

involved_in

PMID:9352365

GO_REF:0000096 RGD:1600138

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

Il2ra

interleukin 2 receptor, alpha chain

involved_in

PMID:9352365

GO_REF:0000096 GO_REF:0000107 RGD:1600138

NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004

Il36b

interleukin 36B

acts_upstream_of_or_within
involved_in

IGI
IBA

(PMID:22968459)

PMID:22968459

GO_REF:0000033

NCBI chr 2:24,043,184...24,050,115
Ensembl chr 2:24,043,173...24,050,531

Il4

interleukin 4

involved_in

GO_REF:0000119

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

Il7

interleukin 7

acts_upstream_of_or_within

(PMID:12431371)

PMID:12431371

NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820

Mdk

midkine

involved_in

(PMID:28183532)

PMID:28183532

NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642

Pbrm1

polybromo 1

involved_in

(PMID:12110891)

NCBI chr14:30,741,095...30,843,549
Ensembl chr14:30,741,095...30,843,549

Phf10

PHD finger protein 10

involved_in

(PMID:12110891)

NCBI chr17:15,165,269...15,181,550
Ensembl chr17:15,165,271...15,181,535

Pik3r6

phosphoinositide-3-kinase regulatory subunit 5

involved_in

(PMID:12707323)

PMID:12707323

NCBI chr11:68,393,845...68,443,524
Ensembl chr11:68,393,845...68,443,524

Ptprc

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

(PMID:8666928)

PMID:8666928

NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446

Rag1

recombination activating 1

involved_in

(PMID:1547488)

PMID:1547488

NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846

Rhoh

ras homolog family member H

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr 5:66,018,092...66,054,043
Ensembl chr 5:66,018,556...66,054,043

Skint1

selection and upkeep of intraepithelial T cells 1

acts_upstream_of_or_within

(PMID:21300860)

PMID:21300860

NCBI chr 4:111,863,466...111,886,735
Ensembl chr 4:111,863,466...111,886,735

Smarca2

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

involved_in

(PMID:12110891)

NCBI chr19:26,582,578...26,755,721
Ensembl chr19:26,582,450...26,755,722

Smarca4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

involved_in

(PMID:12110891)

NCBI chr 9:21,527,377...21,615,526
Ensembl chr 9:21,527,465...21,615,526

Smarcb1

SWI/SNF related BAF chromatin remodeling complex subunit B1

involved_in

(PMID:12110891)

NCBI chr10:75,732,603...75,757,448
Ensembl chr10:75,732,603...75,757,451

Smarcc1

SWI/SNF related BAF chromatin remodeling complex subunit C1

involved_in

(PMID:12110891)

NCBI chr 9:109,961,129...110,069,773
Ensembl chr 9:109,946,776...110,069,246

Smarcc2

SWI/SNF related BAF chromatin remodeling complex subunit C2

involved_in

(PMID:12110891)

NCBI chr10:128,294,823...128,326,460
Ensembl chr10:128,295,117...128,326,351

Smarcd1

SWI/SNF related BAF chromatin remodeling complex subunit D1

involved_in

(PMID:12110891)

NCBI chr15:99,600,175...99,611,872
Ensembl chr15:99,600,010...99,611,872

Smarcd2

SWI/SNF related BAF chromatin remodeling complex subunit D2

involved_in

(PMID:12110891)

NCBI chr11:106,153,997...106,163,810
Ensembl chr11:106,154,005...106,163,798

Smarcd3

SWI/SNF related BAF chromatin remodeling complex subunit D3

involved_in

(PMID:12110891)

NCBI chr 5:24,797,620...24,829,649
Ensembl chr 5:24,795,816...24,829,409

Smarce1

SWI/SNF related BAF chromatin remodeling complex subunit E1

involved_in

(PMID:12110891)

NCBI chr11:99,099,873...99,121,843
Ensembl chr11:99,099,873...99,121,843

Wnt10b

wingless-type MMTV integration site family, member 10B

acts_upstream_of_or_within

(PMID:19723499)

PMID:19723499

NCBI chr15:98,668,593...98,676,093
Ensembl chr15:98,668,593...98,676,031

Xbp1

X-box binding protein 1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893

Zap70

zeta-chain (TCR) associated protein kinase

acts_upstream_of_or_within

(PMID:9208839)

PMID:9208839

GO_REF:0000008

NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899

Zbtb1

zinc finger and BTB domain containing 1

involved_in

(PMID:22201126)

PMID:22201126

NCBI chr12:76,416,825...76,443,729
Ensembl chr12:76,417,040...76,443,724

Zmiz1

zinc finger, MIZ-type containing 1

involved_in

(PMID:26522984)

PMID:26522984

NCBI chr14:25,458,299...25,667,167
Ensembl chr14:25,459,609...25,667,167

positive regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

(PMID:11067867), (PMID:12163459), (PMID:16670300)
(PMID:11435465)
(PMID:11067867), (PMID:16670300)

PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300

NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159

Adam8

a disintegrin and metallopeptidase domain 8

involved_in

(PMID:20856819)

PMID:20856819

NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475

Egr3

early growth response 3

acts_upstream_of_or_within

(PMID:21737317)

NCBI chr14:70,314,766...70,320,062
Ensembl chr14:70,314,652...70,320,063

Indian hedgehog

involved_in

(PMID:19109233)

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

Il2rg

interleukin 2 receptor, gamma chain

acts_upstream_of_or_within

(PMID:9252128)
(PMID:9916699)

PMID:9252128 PMID:9916699

NCBI chr X:100,307,991...100,311,861
Ensembl chr X:100,307,984...100,311,861

Il7r

interleukin 7 receptor

acts_upstream_of_or_within

(PMID:9215626)

PMID:9215626

NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262

Rasgrp1

RAS guanyl releasing protein 1

involved_in

(PMID:11017103)

PMID:11017103

NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482

sonic hedgehog

involved_in

(PMID:19109233)

NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254

Skint1

selection and upkeep of intraepithelial T cells 1

acts_upstream_of_or_within

(PMID:21737317)

NCBI chr 4:111,863,466...111,886,735
Ensembl chr 4:111,863,466...111,886,735

Tespa1

thymocyte expressed, positive selection associated 1

involved_in

(PMID:22561606)

PMID:22561606

NCBI chr10:130,158,696...130,199,338
Ensembl chr10:130,158,739...130,199,980

Vnn1

vanin 1

involved_in

(PMID:8934567)

PMID:8934567

NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241

Zfp609

zinc finger protein 609

involved_in

(PMID:23076336)

PMID:23076336

NCBI chr 9:65,598,860...65,735,004
Ensembl chr 9:65,599,673...65,734,846

positive regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anxa1

annexin A1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308

Ccl19

C-C motif chemokine ligand 19

involved_in

(PMID:15845453)

PMID:15845453

NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577

Ccr2

C-C motif chemokine receptor 2

involved_in

(PMID:14662900)

PMID:14662900

NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594

Ccr7

C-C motif chemokine receptor 7

involved_in

(PMID:15845453)

PMID:15845453

NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903

Hlx

H2.0-like homeobox

acts_upstream_of_or_within

IGI
IMP

(PMID:16424184)

NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816

interferon regulatory factor 1

involved_in

(PMID:11244049)

PMID:11244049

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

Ripk2

receptor (TNFRSF)-interacting serine-threonine kinase 2

acts_upstream_of_or_within

(PMID:11894097)

PMID:11894097

NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647

Socs5

suppressor of cytokine signaling 5

involved_in

(PMID:12242343)

PMID:12242343

NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267

positive regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Malt1

MALT1 paracaspase

involved_in

(PMID:25282160)

NCBI chr18:65,564,010...65,612,138
Ensembl chr18:65,564,009...65,612,138

Mir326

microRNA 326

acts_upstream_of_or_within

IDA
IMP

(PMID:19838199)

PMID:19838199

NCBI chr 7:99,201,476...99,201,570
Ensembl chr 7:99,201,476...99,201,570

Nfkbid

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta

involved_in

(PMID:25282160)

NCBI chr 7:30,121,156...30,128,173
Ensembl chr 7:30,121,157...30,128,171

Nfkbiz

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta

involved_in

(PMID:25282160)

NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262

Nlrp3

NLR family, pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782

positive regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Brd2

bromodomain containing 2

involved_in

ISO
IDA

(PMID:28262505)

PMID:28262505

GO_REF:0000119

NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608

Brd4

bromodomain containing 4

involved_in

(PMID:28262505)

PMID:28262505

NCBI chr17:32,415,246...32,503,717
Ensembl chr17:32,415,248...32,503,696

Ep300

E1A binding protein p300

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278

Il23a

interleukin 23, alpha subunit p19

involved_in

IBA
IDA

(PMID:19501566)

GO_Central
BHF-UCL

PMID:19501566

GO_REF:0000033

NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621

Opa1

OPA1, mitochondrial dynamin like GTPase

involved_in

(PMID:36171294)

PMID:36171294

NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702

positive regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il18

interleukin 18

involved_in

(PMID:12829194)

PMID:12829194

NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140

Il4ra

interleukin 4 receptor, alpha

acts_upstream_of_or_within

(PMID:16424184)

NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646

Il6

interleukin 6

acts_upstream_of_or_within

(PMID:12594267)

PMID:12594267

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

Nlrp3

NLR family, pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782

Prkcz

protein kinase C, zeta

involved_in

(PMID:15987782)

PMID:15987782

NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818

Rara

retinoic acid receptor, alpha

involved_in

GO_REF:0000107 GO_REF:0000119

NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768

tumor necrosis factor (ligand) superfamily, member 4

involved_in

(PMID:18354165)

PMID:18354165

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

positive regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Shb

src homology 2 domain-containing transforming protein B

acts_upstream_of_or_within

(PMID:24645804)

PMID:24645804

NCBI chr 4:45,423,278...45,530,804
Ensembl chr 4:45,423,278...45,532,470

regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ankle1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr 8:71,858,630...71,868,475
Ensembl chr 8:71,858,654...71,862,548

regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ankle1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr 8:71,858,630...71,868,475
Ensembl chr 8:71,858,654...71,862,548

Card11

caspase recruitment domain family, member 11

acts_upstream_of_or_within

(PMID:12867038)

PMID:12867038

NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337

Cd24a

CD24a antigen

acts_upstream_of_or_within

(PMID:7795661), (PMID:9028339)

PMID:7795661 PMID:9028339

NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261

Cyld

CYLD lysine 63 deubiquitinase

acts_upstream_of_or_within

(PMID:16501569)

PMID:16501569

NCBI chr 8:89,423,506...89,478,574
Ensembl chr 8:89,423,675...89,478,573

Fas

Fas cell surface death receptor

acts_upstream_of_or_within

(PMID:6610701)

PMID:6610701

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

Ikzf3

IKAROS family zinc finger 3

involved_in

(PMID:9806640)

PMID:9806640

NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857

Il4i1

interleukin 4 induced 1

involved_in

(PMID:29288206)

PMID:29288206

NCBI chr 7:44,485,712...44,490,233
Ensembl chr 7:44,465,811...44,490,233

Mir150

microRNA 150

acts_upstream_of_or_within

(PMID:17927961)

PMID:17927961

NCBI chr 7:44,771,181...44,771,245
Ensembl chr 7:44,771,181...44,771,245

Nfam1

Nfat activating molecule with ITAM motif 1

acts_upstream_of_or_within

(PMID:15143214)

PMID:15143214

NCBI chr15:82,880,937...82,917,598
Ensembl chr15:82,877,174...82,917,507

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

acts_upstream_of_or_within

(PMID:9254656)

PMID:9254656

NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677

Slamf8

SLAM family member 8

involved_in

(PMID:11313408)

PMID:11313408

NCBI chr 1:172,408,944...172,418,482
Ensembl chr 1:172,409,325...172,418,135

Tlr9

toll-like receptor 9

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082

Zfp36l1

zinc finger protein 36, C3H type-like 1

involved_in

(PMID:27102483)

PMID:27102483

NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787

Zfp36l2

zinc finger protein 36, C3H type-like 2

involved_in

(PMID:27102483)

PMID:27102483

NCBI chr17:84,491,352...84,495,375
Ensembl chr17:84,491,359...84,495,375

regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Sh3rf1

SH3 domain containing ring finger 1

involved_in

(PMID:27084103)

PMID:27084103

NCBI chr 8:61,677,117...61,918,327
Ensembl chr 8:61,676,906...61,849,105

regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Kcnk18

potassium channel, subfamily K, member 18

involved_in

(PMID:34702947)

PMID:34702947

NCBI chr19:59,208,080...59,225,802
Ensembl chr19:59,207,646...59,225,806

transforming growth factor, beta 1

involved_in

(PMID:18368049)

PMID:18368049

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

(PMID:18776904)

PMID:18776904

NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083

regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cebpb

CCAAT/enhancer binding protein beta

involved_in

(PMID:26526992)

PMID:26526992

NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338

H2-M2

histocompatibility 2, M region locus 2

involved_in

(PMID:20008523)

PMID:20008523

NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443

regulation of extrathymic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Prdm1

PR domain containing 1, with ZNF domain

involved_in

(PMID:27102484)

NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497

zinc finger protein 683

involved_in

(PMID:27102484)

NCBI chr 4:133,778,506...133,786,252
Ensembl chr 4:133,781,149...133,786,307

regulation of gamma-delta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Egr3

early growth response 3

acts_upstream_of_or_within

(PMID:21737317)

NCBI chr14:70,314,766...70,320,062
Ensembl chr14:70,314,652...70,320,063

Rorc

RAR-related orphan receptor gamma

acts_upstream_of_or_within

(PMID:21737317)

NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583

Sox13

SRY (sex determining region Y)-box 13

acts_upstream_of_or_within

(PMID:21737317)

NCBI chr 1:133,310,038...133,352,159
Ensembl chr 1:133,310,041...133,352,115

Tcf7

transcription factor 7, T cell specific

involved_in

(PMID:23562159)

NCBI chr11:52,137,347...52,174,211
Ensembl chr11:52,143,198...52,174,158

regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Rara

retinoic acid receptor, alpha

acts_upstream_of_or_within

(PMID:11222375)

PMID:11222375

NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768

Rbp1

retinol binding protein 1, cellular

acts_upstream_of_or_within

(PMID:11222375)

PMID:11222375

NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628

regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ikzf3

IKAROS family zinc finger 3

involved_in

(PMID:9155026)

PMID:9155026

NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857

Ndfip1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

(PMID:17137798)

PMID:17137798

NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356

Rnf41

ring finger protein 41

acts_upstream_of_or_within

(PMID:18495327)

PMID:18495327

NCBI chr10:128,247,485...128,277,310
Ensembl chr10:128,247,526...128,277,310

regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Qki

quaking, KH domain containing RNA binding

involved_in

GO_REF:0000119

NCBI chr17:10,425,480...10,538,706
Ensembl chr17:10,421,530...10,538,783

regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tal1

T cell acute lymphocytic leukemia 1

acts_upstream_of_or_within

(PMID:17644741)

PMID:17644741

NCBI chr 4:114,913,623...114,928,952
Ensembl chr 4:114,913,623...114,928,952

regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B cell leukemia/lymphoma 6

acts_upstream_of_or_within

(PMID:15240675)

PMID:15240675

NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602

regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Foxp1

forkhead box P1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682

regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ndfip1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

(PMID:17137798)

PMID:17137798

NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356

regulation of natural killer cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

lectin, galactose binding, soluble 9

involved_in

(PMID:23408620)

PMID:23408620

NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772

Prdm1

PR domain containing 1, with ZNF domain

involved_in

(PMID:27102484)

NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497

zinc finger protein 683

involved_in

(PMID:27102484)

NCBI chr 4:133,778,506...133,786,252
Ensembl chr 4:133,781,149...133,786,307

regulation of natural killer cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

zinc finger protein 683

involved_in

(PMID:22885984)

PMID:22885984

NCBI chr 4:133,778,506...133,786,252
Ensembl chr 4:133,781,149...133,786,307

regulation of NK T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Prdm1

PR domain containing 1, with ZNF domain

involved_in

(PMID:27102484)

NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497

zinc finger protein 683

involved_in

(PMID:27102484)

NCBI chr 4:133,778,506...133,786,252
Ensembl chr 4:133,781,149...133,786,307

regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adam8

a disintegrin and metallopeptidase domain 8

involved_in

(PMID:18397961)

PMID:18397961

NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475

Apc

APC, WNT signaling pathway regulator

acts_upstream_of_or_within

(PMID:15802266)

PMID:15802266

NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605

Cebpb

CCAAT/enhancer binding protein beta

involved_in

(PMID:19440205)

PMID:19440205

NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338

Ctnnb1

catenin beta 1

acts_upstream_of_or_within

(PMID:15802266)

PMID:15802266

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

Esrra

estrogen related receptor, alpha

involved_in

PMID:12193582

GO_REF:0000096 RGD:625668

NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208

Fgfr3

fibroblast growth factor receptor 3

acts_upstream_of_or_within

(PMID:20053668)

PMID:20053668

NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412

Fshb

follicle stimulating hormone beta

acts_upstream_of_or_within

(PMID:16630814)

PMID:16630814

NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001

Fshr

follicle stimulating hormone receptor

acts_upstream_of_or_within

(PMID:16630814)

PMID:16630814

NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103

Mir9718

microRNA 9718

acts_upstream_of_or_within

(PMID:25019593)

PMID:25019593

NCBI chr12:73,092,659...73,092,722
Ensembl chr12:73,092,659...73,092,722

Mitf

melanogenesis associated transcription factor

acts_upstream_of_or_within

(PMID:11930005)

PMID:11930005

NCBI chr 6:97,783,966...97,998,321
Ensembl chr 6:97,784,013...97,998,310

Mtor

mechanistic target of rapamycin kinase

involved_in

(PMID:19440205)

PMID:19440205

NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140

Prxl2a

peroxiredoxin like 2A

involved_in

GO_REF:0000119

NCBI chr14:40,715,692...40,735,790
Ensembl chr14:40,715,697...40,735,745

Rassf2

Ras association (RalGDS/AF-6) domain family member 2

acts_upstream_of_or_within

(PMID:22227519)

PMID:22227519

NCBI chr 2:131,834,770...131,872,336
Ensembl chr 2:131,831,335...131,872,178

Tfe3

transcription factor E3

acts_upstream_of_or_within

(PMID:11930005)

PMID:11930005

NCBI chr X:7,628,769...7,641,441
Ensembl chr X:7,628,799...7,641,441

Tnf

tumor necrosis factor

acts_upstream_of_or_within

(PMID:12490655)

PMID:12490655

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

Tnfsf11

tumor necrosis factor (ligand) superfamily, member 11

acts_upstream_of_or_within

(PMID:12490655), (PMID:23395171)

PMID:12490655 PMID:23395171

NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483

Ubash3b

ubiquitin associated and SH3 domain containing, B

involved_in

(PMID:23149425)

GO_Central
CACAO

PMID:23149425

GO_REF:0000033

NCBI chr 9:40,922,056...41,069,358
Ensembl chr 9:40,922,394...41,072,993

Zbtb7a

zinc finger and BTB domain containing 7a

involved_in

PMID:10477728

GO_REF:0000096 RGD:633299

NCBI chr10:80,971,113...80,988,056
Ensembl chr10:80,971,054...80,988,829

regulation of positive thymic T cell selection

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Foxn1

forkhead box N1

involved_in

(PMID:24184560)

PMID:24184560

NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384

Tox

thymocyte selection-associated high mobility group box

involved_in

(PMID:18195075)

PMID:18195075

NCBI chr 4:6,686,353...6,991,557
Ensembl chr 4:6,686,353...6,991,557

regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd28

CD28 antigen

acts_upstream_of_or_within

(PMID:21245484)

PMID:21245484

NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518

Ctla2a

cytotoxic T lymphocyte-associated protein 2 alpha

acts_upstream_of_or_within

(PMID:21245393)

PMID:21245393

NCBI chr13:61,081,969...61,084,439
Ensembl chr13:61,081,969...61,084,439

Dicer1

dicer 1, ribonuclease type III

acts_upstream_of_or_within

(PMID:18725527)

PMID:18725527

NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211

Drosha

drosha, ribonuclease type III

acts_upstream_of_or_within

(PMID:18725527)

PMID:18725527

NCBI chr15:12,824,893...12,935,377
Ensembl chr15:12,824,901...12,935,377

Fanca

Fanconi anemia, complementation group A

acts_upstream_of_or_within
involved_in

IMP
IBA

(PMID:24501220)

PMID:24501220

GO_REF:0000033

NCBI chr 8:123,993,033...124,045,390
Ensembl chr 8:123,995,039...124,045,315

Fancd2

Fanconi anemia, complementation group D2

acts_upstream_of_or_within

(PMID:24501220)

PMID:24501220

NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978

Kat2a

K(lysine) acetyltransferase 2A

involved_in

(PMID:28424240)

PMID:28424240

NCBI chr11:100,595,572...100,603,293
Ensembl chr11:100,595,572...100,603,291

Lck

lymphocyte protein tyrosine kinase

acts_upstream_of_or_within

(PMID:21245484)

PMID:21245484

NCBI chr 4:129,442,142...129,467,415
Ensembl chr 4:129,442,137...129,467,434

Sh2b3

SH2B adaptor protein 3

involved_in

PMID:25776069

GO_REF:0000096 RGD:13442483

NCBI chr 5:121,953,544...121,975,706
Ensembl chr 5:121,953,551...121,975,709

transforming growth factor, beta 1

acts_upstream_of_or_within

(PMID:21245484)

PMID:21245484

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abl1

c-abl oncogene 1, non-receptor tyrosine kinase

involved_in

(PMID:21690296)

PMID:21690296

NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239

adenosine deaminase

acts_upstream_of_or_within

(PMID:7670465)

PMID:7670465

NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159

Braf

Braf transforming gene

acts_upstream_of_or_within

(PMID:18228248)

PMID:18228248

NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397

Card11

caspase recruitment domain family, member 11

acts_upstream_of_or_within

(PMID:12867038)

PMID:12867038

NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337

Ccr2

C-C motif chemokine receptor 2

involved_in

(PMID:28507030)

PMID:28507030

NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594

Crtam

cytotoxic and regulatory T cell molecule

involved_in

(PMID:24687959)

PMID:24687959

NCBI chr 9:40,880,987...40,915,922
Ensembl chr 9:40,880,987...40,915,924

Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

acts_upstream_of_or_within

(PMID:23991089)

PMID:23991089

NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890

Duxbl1

double homeobox B-like 1

acts_upstream_of_or_within

(PMID:17911620)

PMID:17911620

NCBI chr14:25,979,011...25,990,590
Ensembl chr14:25,979,001...25,990,512

Fas

Fas cell surface death receptor

acts_upstream_of_or_within

(PMID:6610701)

PMID:6610701

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

H2-Oa

histocompatibility 2, O region alpha locus

acts_upstream_of_or_within

(PMID:11069069)

PMID:11069069

NCBI chr17:34,311,353...34,314,286
Ensembl chr17:34,311,314...34,314,208

Il15

interleukin 15

acts_upstream_of_or_within

(PMID:10704459)

PMID:10704459

NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851

Mettl3

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

involved_in

(PMID:28792938)

PMID:28792938

NCBI chr14:52,532,298...52,548,555
Ensembl chr14:52,532,298...52,542,585

Prelid1

PRELI domain containing 1

involved_in

GO_REF:0000024 GO_REF:0000119

NCBI chr13:55,469,868...55,473,085
Ensembl chr13:55,468,313...55,473,085

Rag1

recombination activating 1

acts_upstream_of_or_within

(PMID:18684012)

PMID:18684012

NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846

Slc46a2

solute carrier family 46, member 2

acts_upstream_of_or_within

(PMID:18684012)

PMID:18684012

NCBI chr 4:59,905,899...59,915,056
Ensembl chr 4:59,905,126...59,915,056

Tbx21

T-box 21

involved_in

(PMID:21690296)

PMID:21690296

NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157

regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

involved_in

PMID:3876160

GO_REF:0000096 RGD:152995412

NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159

Adrm1

adhesion regulating molecule 1 26S proteasome ubiquitin receptor

involved_in

(PMID:21048919)

PMID:21048919

NCBI chr 2:179,813,381...179,818,076
Ensembl chr 2:179,813,278...179,818,079

Ankle1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr 8:71,858,630...71,868,475
Ensembl chr 8:71,858,654...71,862,548

Clptm1

cleft lip and palate associated transmembrane protein 1

involved_in

(PMID:9218588)

PMID:9218588

NCBI chr 7:19,365,505...19,398,955
Ensembl chr 7:19,365,496...19,398,958

Foxn1

forkhead box N1

acts_upstream_of_or_within

(PMID:22072979)

PMID:22072979

NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384

lectin, galactose binding, soluble 9

NOT|involved_in

(PMID:25065622)

NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772

Sos1

SOS Ras/Rac guanine nucleotide exchange factor 1

acts_upstream_of_or_within

(PMID:24043312)

PMID:24043312

NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882

Sos2

SOS Ras/Rho guanine nucleotide exchange factor 2

acts_upstream_of_or_within

(PMID:24043312)

PMID:24043312

NCBI chr12:69,630,535...69,728,626
Ensembl chr12:69,630,536...69,728,626

Zeb1

zinc finger E-box binding homeobox 1

acts_upstream_of_or_within

(PMID:9389660)
(PMID:9126927)

PMID:9126927 PMID:9389660

NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467

regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il27

interleukin 27

involved_in

IBA
ISO
IEA

GO_REF:0000033 GO_REF:0000107 GO_REF:0000119

NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113

regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ccl20

C-C motif chemokine ligand 20

NOT|involved_in

(PMID:19050256)

PMID:19050256

NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888

Ccr6

C-C motif chemokine receptor 6

NOT|involved_in

(PMID:19050256)

PMID:19050256

NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973

Mir301

microRNA 301

acts_upstream_of_or_within

(PMID:22517757)

PMID:22517757

NCBI chr11:87,003,830...87,003,915
Ensembl chr11:87,003,830...87,003,915

regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gata3

GATA binding protein 3

acts_upstream_of_or_within

(PMID:18776904)

PMID:18776904

NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845

H2-Ea

histocompatibility 2, class II antigen E alpha

involved_in

GO_REF:0000119

NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618

histocompatibility 2, class II antigen E beta

involved_in

(PMID:15322540)

PMID:15322540

NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

(PMID:18776904)