regulation of leukocyte differentiation - Ontology Report

GO_REF:0000107

NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

sonic hedgehog signaling molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

negative regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FLT3

fms related receptor tyrosine kinase 3

acts_upstream_of_or_within

(PMID:16618805)

PMID:16618805

NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284

HMGB3

high mobility group box 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:119,152,166...119,159,803
Ensembl chr X:119,155,786...119,159,814

ID2

inhibitor of DNA binding 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:5,956,924...5,958,833

LOC102151783

inhibitor of DNA binding 2

acts_upstream_of_or_within

(PMID:18523151)

PMID:18523151

NCBI chr10:54,954,852...54,957,116

SFRP1

secreted frizzled related protein 1

involved_in

GO_REF:0000107

NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964

negative regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBFB

core-binding factor subunit beta

involved_in

(PMID:18258917)

NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168

HMGB1

high mobility group box 1

involved_in

GO_REF:0000107

NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165

RUNX family transcription factor 1

involved_in

(PMID:18258917)

NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839

RUNX3

RUNX family transcription factor 3

involved_in

(PMID:18258917)

negative regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC4A2

solute carrier family 4 member 2

involved_in

(PMID:24515893)

PMID:24515893

NCBI chr16:15,111,078...15,126,618
Ensembl chr16:15,111,116...15,126,617

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

negative regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:16493035)

PMID:16493035

NCBI chr 1:102,779,562...102,786,924

negative regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CLEC12A

C-type lectin domain family 12 member A

involved_in

GO_REF:0000107

NCBI chr27:36,040,574...36,051,249
Ensembl chr27:36,040,577...36,051,184

TMEM176A

transmembrane protein 176A

acts_upstream_of_or_within

(PMID:20501748)

PMID:20501748

NCBI chr16:14,927,031...14,931,350
Ensembl chr16:14,926,805...14,931,238

TMEM176B

transmembrane protein 176B

acts_upstream_of_or_within
involved_in

ISO
IBA

(PMID:20501748)

MGI
GO_Central

PMID:20501748

GO_REF:0000033

NCBI chr16:14,918,491...14,926,673
Ensembl chr16:14,919,126...14,926,583

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:47,290,696...47,329,342
Ensembl chr24:47,292,684...47,329,570

negative regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

involved_in

IEA
ISS

Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844

C1QC

complement C1q C chain

involved_in

GO_REF:0000107

NCBI chr 2:76,660,039...76,664,602
Ensembl chr 2:76,660,035...76,664,577

CEACAM1

CEA cell adhesion molecule 1

involved_in

(PMID:21029969)

PMID:21029969

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

CUL4A

cullin 4A

acts_upstream_of_or_within

(PMID:12393421)

PMID:12393421

NCBI chr22:60,624,215...60,667,844
Ensembl chr22:60,624,241...60,666,616

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200

PRDM16

PR/SET domain 16

involved_in

(PMID:12816872)

PMID:12816872

NCBI chr 5:57,805,951...58,018,817
Ensembl chr 5:57,730,370...58,017,976

RARA

retinoic acid receptor alpha

involved_in

GO_REF:0000107

NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459

RUNX family transcription factor 1

involved_in

(PMID:9199349)

PMID:9199349

NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:47,290,696...47,329,342
Ensembl chr24:47,292,684...47,329,570

negative regulation of immature T cell proliferation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557

CDKN2A

cyclin dependent kinase inhibitor 2A

involved_in

(PMID:15964995)

HGNC-UCL

PMID:15964995

NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379

CLEC4G

C-type lectin domain family 4 member G

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:52,476,162...52,480,341
Ensembl chr20:52,476,200...52,479,930

ERBB2

erb-b2 receptor tyrosine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

TMEM131L

transmembrane 131 like

involved_in

GO_REF:0000107

NCBI chr15:51,268,897...51,427,347
Ensembl chr15:51,268,855...51,427,212

negative regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FBXO7

F-box protein 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977

negative regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

involved_in

IEA
ISS

Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844

C1QC

complement C1q C chain

involved_in

GO_REF:0000107

NCBI chr 2:76,660,039...76,664,602
Ensembl chr 2:76,660,035...76,664,577

GATA2

GATA binding protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991

MIR486

microRNA mir-486

involved_in

(PMID:25857263)

PMID:25857263

NCBI chr16:23,958,963...23,959,026
Ensembl chr16:23,958,963...23,959,026

PTPN2

protein tyrosine phosphatase non-receptor type 2

involved_in

GO_REF:0000107

NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719

QKI

QKI, KH domain containing RNA binding

involved_in

ISS

GO_REF:0000024

NCBI chr 1:51,800,294...51,956,891
Ensembl chr 1:51,800,309...51,952,714

TAOK3

TAO kinase 3

involved_in

GO_REF:0000107

NCBI chr26:14,534,083...14,712,779
Ensembl chr26:14,534,901...14,631,899

THOC5

THO complex subunit 5

acts_upstream_of_or_within

(PMID:10597251)

PMID:10597251

NCBI chr26:22,748,857...22,785,288
Ensembl chr26:22,748,895...22,784,143

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:47,290,696...47,329,342
Ensembl chr24:47,292,684...47,329,570

negative regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ZFPM1

zinc finger protein, FOG family member 1

involved_in

GO_REF:0000107

NCBI chr 5:64,812,353...64,863,278

negative regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGL2

fibrinogen like 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr18:17,328,794...17,335,429
Ensembl chr18:17,331,780...17,335,401

IL29L

interleukin 29-like

involved_in

(PMID:19346497)

PMID:19346497

NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017

negative regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDK6

cyclin dependent kinase 6

involved_in

GO_REF:0000107

NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869

GPR68

G protein-coupled receptor 68

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:62,090,050...62,108,922
Ensembl chr 8:62,092,135...62,093,217

HOXA7

homeobox A7

involved_in

GO_REF:0000107

NCBI chr14:40,327,918...40,334,073
Ensembl chr14:40,329,127...40,330,842

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200

MIR125B-1

microRNA mir-125b-1

involved_in

(PMID:28389358)

PMID:28389358

NCBI chr 5:12,097,672...12,097,732
Ensembl chr 5:12,097,658...12,097,745

MIR125B-2

microRNA mir-125b-2

involved_in

(PMID:28389358)

PMID:28389358

NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052

MYC

MYC proto-oncogene, bHLH transcription factor

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:47,290,696...47,329,342
Ensembl chr24:47,292,684...47,329,570

negative regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LYN

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507

NME1

non-metastatic cells 1, protein (NM23A) expressed in

NCBI chr 9:26,990,336...26,998,895
Ensembl chr 9:26,990,469...26,998,955

NME2

non-metastatic cells 2, protein (NM23B) expressed in

NCBI chr 9:27,002,114...27,005,740
Ensembl chr 9:27,001,733...27,015,934

negative regulation of natural killer cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PGLYRP1

peptidoglycan recognition protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:109,614,404...109,618,242
Ensembl chr 1:109,614,437...109,618,242

PGLYRP2

peptidoglycan recognition protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:46,724,906...46,730,227
Ensembl chr20:46,726,224...46,730,321

negative regulation of neutrophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200

TRIB1

tribbles pseudokinase 1

involved_in

(PMID:23515163)

CACAO

PMID:23515163

NCBI chr13:23,337,788...23,346,304
Ensembl chr13:23,337,788...23,346,304

negative regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CLDN18

claudin 18

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr23:34,229,115...34,257,431
Ensembl chr23:34,228,992...34,255,650

FBN1

fibrillin 1

involved_in

GO_REF:0000107

NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151

FBXW7

F-box and WD repeat domain containing 7

involved_in

GO_REF:0000107

NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195

TJP2

tight junction protein 2

acts_upstream_of_or_within

(PMID:22437732)

PMID:22437732

NCBI chr 1:88,126,134...88,251,018
Ensembl chr 1:88,126,136...88,230,654

negative regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCL3

chemokine (C-C motif) ligand 3

involved_in

ISS

GO_REF:0000024

NCBI chr 9:37,693,711...37,695,137
Ensembl chr 9:37,686,480...37,695,573

CEACAM1

CEA cell adhesion molecule 1

acts_upstream_of_or_within

(PMID:25490771)

PMID:25490771

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

CRSP-3

calcitonin receptor-stimulating peptide 3

involved_in

(PMID:10822112)

PMID:10822112

NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645

CTNNB1

catenin beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927

ERFE

erythroferrone

acts_upstream_of

GO_REF:0000107

NCBI chr25:48,656,576...48,665,620

FBN1

fibrillin 1

involved_in

GO_REF:0000107

NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151

FSTL3

follistatin like 3

involved_in

GO_REF:0000107

NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172

GPR137

G protein-coupled receptor 137

involved_in

IBA

GO_Central

GO_REF:0000033

NCBI chr18:52,776,857...52,781,050
Ensembl chr18:52,776,858...52,779,783

GPR137B

G protein-coupled receptor 137B

involved_in

IBA

GO_Central

GO_REF:0000033

NCBI chr 4:3,819,338...3,864,690
Ensembl chr 4:3,825,602...3,864,780

GPR55

G protein-coupled receptor 55

involved_in

GO_REF:0000107

NCBI chr25:42,864,869...42,931,786
Ensembl chr25:42,866,416...42,908,332

IAPP

islet amyloid polypeptide

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr27:26,295,481...26,299,967
Ensembl chr27:26,295,481...26,299,967

IFNB1

interferon beta 1

acts_upstream_of_or_within

(PMID:17442941)

PMID:17442941

NCBI chr11:40,668,295...40,668,855
Ensembl chr11:40,668,295...40,668,855

IFNG

interferon gamma

acts_upstream_of_or_within

(PMID:17442941)

PMID:12941478 PMID:17442941

PMID:17442941

NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698

IL4

interleukin 4

involved_in
acts_upstream_of_or_within

ISS
ISO

(PMID:12941478), (PMID:17442941)

UniProt
MGI

GO_REF:0000024

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

INPP4B

inositol polyphosphate-4-phosphatase type II B

acts_upstream_of_or_within

(PMID:21982707)

PMID:21982707

NCBI chr19:826,711...1,192,340
Ensembl chr19:850,784...1,186,498

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200

LOC480600

chemokine (C-C motif) ligand 3

involved_in

(PMID:21403648)

PMID:21403648

NCBI chr 9:37,708,561...37,710,209
Ensembl chr 9:37,676,966...37,710,209

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:18802077)

PMID:18802077

NCBI chr 1:102,779,562...102,786,924

LOC611446

leukocyte immunoglobulin-like receptor subfamily A member 6

involved_in

(PMID:18802077)

PMID:18802077

NCBI chr 1:102,955,916...102,978,669

LRRC17

leucine rich repeat containing 17

involved_in

GO_REF:0000107

NCBI chr18:17,103,834...17,132,653
Ensembl chr18:17,104,184...17,118,012

MAFB

MAF bZIP transcription factor B

involved_in

GO_REF:0000107

NCBI chr24:28,769,904...28,772,519
Ensembl chr24:28,770,944...28,774,948

NF1

neurofibromin 1

acts_upstream_of_or_within

(PMID:17053831)

PMID:17053831

NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382

PIAS3

protein inhibitor of activated STAT 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:58,650,791...58,660,755
Ensembl chr17:58,571,694...58,660,663

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970

RNF115

ring finger protein 115

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:58,566,761...58,634,967
Ensembl chr17:58,571,694...58,660,663

SFRP1

secreted frizzled related protein 1

acts_upstream_of_or_within

ISO
IEA

RGD
Ensembl

PMID:17540629

GO_REF:0000107 RGD:4107086

NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964

TCTA

T cell leukemia translocation altered

involved_in

GO_REF:0000107

NCBI chr20:39,820,845...39,824,526
Ensembl chr20:39,822,211...39,824,200

TMEM178A

transmembrane protein 178A

involved_in

GO_REF:0000107

NCBI chr17:31,633,547...31,684,126
Ensembl chr17:31,633,467...31,683,786

TNFAIP6

TNF alpha induced protein 6

involved_in

GO_REF:0000107

NCBI chr19:52,607,598...52,623,799
Ensembl chr19:52,607,713...52,623,811

TNFRSF11B

TNF receptor superfamily member 11b

acts_upstream_of_or_within
involved_in

IEA
ISO

(PMID:9168977)

Ensembl
ComplexPortal

PMID:9168977

GO_REF:0000107

NCBI chr13:18,155,765...18,183,263
Ensembl chr13:18,156,367...18,183,444

TOB2

transducer of ERBB2, 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:23,817,778...23,830,330
Ensembl chr10:23,826,437...23,827,447

UBASH3B

ubiquitin associated and SH3 domain containing B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675

negative regulation of plasma cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BCL6 transcription repressor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704

LOC490269

complement receptor type 2

acts_upstream_of

(PMID:22962438)

PMID:22962438

NCBI chr 7:6,456,238...6,480,672

receptor transporter protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428

negative regulation of positive thymic T cell selection

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PTPN2

protein tyrosine phosphatase non-receptor type 2

involved_in

GO_REF:0000107

NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719

negative regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD44

CD44 molecule

involved_in

(PMID:25065622)

NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107

CTLA4

cytotoxic T-lymphocyte associated protein 4

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874

HSPB1

heat shock protein family B (small) member 1

NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576

IRF1

interferon regulatory factor 1

involved_in

GO_REF:0000107

NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608

LAG3

lymphocyte activating 3

involved_in

GO_REF:0000107

NCBI chr27:38,260,673...38,266,771
Ensembl chr27:38,260,674...38,265,819

MDK

midkine

involved_in

(PMID:22323540)

microRNA mir-21

involved_in

(PMID:22387553)

PMID:22387553

NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624

MIR30B

microRNA mir-30b

involved_in

(PMID:22387553)

PMID:22387553

NCBI chr13:30,906,038...30,906,097
Ensembl chr13:30,906,038...30,906,097

TNF superfamily member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

TUG1

taurine up-regulated 1

NCBI chr26:23,993,804...24,003,508

negative regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD74

CD74 molecule

acts_upstream_of_or_within

(PMID:7679955)

PMID:7679955

NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151

DTX1

deltex E3 ubiquitin ligase 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr26:10,469,850...10,502,682

IFNB1

interferon beta 1

involved_in

GO_REF:0000107

NCBI chr11:40,668,295...40,668,855
Ensembl chr11:40,668,295...40,668,855

IL29L

interleukin 29-like

involved_in

(PMID:19346497)

PMID:19346497

NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017

NRARP

NOTCH regulated ankyrin repeat protein

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:48,394,568...48,396,849
Ensembl chr 9:48,394,754...48,395,098

PRDX2

peroxiredoxin 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682

negative regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557

FOXJ1

forkhead box J1

involved_in

GO_REF:0000107

NCBI chr 9:4,512,898...4,517,764
Ensembl chr 9:4,513,628...4,517,756

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

NFKBID

NFKB inhibitor delta

acts_upstream_of_or_within

(PMID:11931770)

PMID:11931770

NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325

RAG2

recombination activating 2

NCBI chr18:31,614,143...31,621,489
Ensembl chr18:31,618,481...31,620,064

sonic hedgehog signaling molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

ZC3H8

zinc finger CCCH-type containing 8

involved_in

GO_REF:0000107

NCBI chr17:36,584,828...36,621,194
Ensembl chr17:36,597,916...36,613,722

negative regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

GO_REF:0000107

NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975

IL4R

interleukin 4 receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291

JAK3

Janus kinase 3

involved_in

(PMID:16020505)

PMID:16020505

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

TNF superfamily member 4

involved_in

(PMID:9670042)

PMID:9670042

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

negative regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

GO_REF:0000107

NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975

forkhead box P3

involved_in

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

IL2

interleukin 2

involved_in

GO_REF:0000107

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

IL4

interleukin 4

acts_upstream_of_or_within

(PMID:18792410)

PMID:18792410

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

RC3H1

ring finger and CCCH-type domains 1

involved_in

GO_REF:0000107

NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174

RC3H2

ring finger and CCCH-type domains 2

involved_in

GO_REF:0000107

NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341

SMAD7

SMAD family member 7

involved_in

GO_REF:0000107

NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

ZC3H12A

zinc finger CCCH-type containing 12A

involved_in

GO_REF:0000107

NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371

negative regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD69

CD69 molecule

involved_in

GO_REF:0000107

NCBI chr27:36,197,202...36,205,045
Ensembl chr27:36,197,175...36,204,597

JAK3

Janus kinase 3

involved_in

GO_REF:0000107

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

LGALS1

galectin 1

involved_in

(PMID:24752896)

PMID:24752896

NCBI chr10:26,932,351...26,935,580
Ensembl chr10:26,932,301...26,935,646

LOXL3

lysyl oxidase like 3

involved_in

GO_REF:0000107

NCBI chr17:48,590,996...48,610,264
Ensembl chr17:48,591,768...48,610,392

signal transducer and activator of transcription 5A

involved_in

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261

TNFSF18

TNF superfamily member 18

involved_in

(PMID:24107315)

PMID:24107315

NCBI chr 7:25,983,064...25,994,605
Ensembl chr 7:25,963,719...25,992,801

negative regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA1

annexin A1

involved_in

GO_REF:0000107

NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

GO_REF:0000107

NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975

BCL6 transcription repressor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704

HLX

H2.0 like homeobox

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152

LOC111089966

zinc finger protein 271

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:54,714,912...54,727,638

receptor transporter protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428

SOCS5

suppressor of cytokine signaling 5

involved_in

GO_REF:0000107

NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452

negative regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RC3H1

ring finger and CCCH-type domains 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174

positive regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

GLI3

GLI family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

ITPKB

inositol-trisphosphate 3-kinase B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:38,253,257...38,346,400
Ensembl chr 7:38,253,407...38,343,345

NKAP

NFKB activating protein

involved_in

GO_REF:0000107

NCBI chr X:91,922,326...91,956,566
Ensembl chr X:91,923,550...91,956,414

PNP

purine nucleoside phosphorylase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr15:17,808,454...17,815,987
Ensembl chr15:17,808,461...17,815,676

RHOA

ras homolog family member A

involved_in

GO_REF:0000107

NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

SYK

spleen associated tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

ZAP70

zeta chain of T cell receptor associated protein kinase 70

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071

positive regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP11C

ATPase phospholipid transporting 11C

involved_in

GO_REF:0000107

NCBI chr X:109,695,018...109,888,284
Ensembl chr X:109,697,086...109,880,624

BAD

BCL2 associated agonist of cell death

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405

CD27

CD27 molecule

involved_in

InterPro

GO_REF:0000002

NCBI chr27:38,534,704...38,537,806
Ensembl chr27:38,534,707...38,537,604

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:55,480,846...55,488,485
Ensembl chr X:55,481,092...55,484,751

IL7

interleukin 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200

MMP14

matrix metallopeptidase 14

involved_in

GO_REF:0000107

NCBI chr 8:3,183,419...3,193,079
Ensembl chr 8:3,183,606...3,194,122

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

PCID2

PCI domain containing 2

involved_in

GO_REF:0000107

NCBI chr22:60,602,440...60,623,811
Ensembl chr22:60,602,888...60,623,719

PPP2R3C

protein phosphatase 2 regulatory subunit B''gamma

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:13,863,017...13,885,245
Ensembl chr 8:13,863,380...13,885,130

SPI1

Spi-1 proto-oncogene

involved_in

GO_REF:0000107

NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485

SYK

spleen associated tyrosine kinase

acts_upstream_of_or_within
involved_in

GO_REF:0000107

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

XBP1

X-box binding protein 1

involved_in

GO_REF:0000107

NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105

positive regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD83

CD83 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr35:13,489,046...13,507,897
Ensembl chr35:13,489,000...13,507,068

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

SASH3

SAM and SH3 domain containing 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:100,989,605...101,003,162
Ensembl chr X:100,989,685...101,001,885

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557

TNF superfamily member 4

involved_in

(PMID:20639485)

PMID:20639485

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DLA-DRA

MHC class II DR alpha chain

involved_in

GO_REF:0000107

NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975

MHC class II DLA DRB1 beta chain

involved_in

(PMID:28467828)

PMID:28467828

NCBI chr12:2,151,409...2,164,564

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:55,480,846...55,488,485
Ensembl chr X:55,481,092...55,484,751

KLHL25

kelch like family member 25

involved_in

(PMID:34491895)

PMID:34491895

NCBI chr 3:49,339,576...49,375,473
Ensembl chr 3:49,348,982...49,351,663

LOC100687459

GTPase IMAP family member 5

NCBI chr16:14,887,308...14,895,522

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IFNG

interferon gamma

involved_in

GO_REF:0000107

NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698

galectin 9

involved_in

(PMID:20209097)

PMID:20209097

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

positive regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBFB

core-binding factor subunit beta

involved_in

(PMID:18258917)

NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:18420485)

PMID:18420485

NCBI chr 1:102,779,562...102,786,924

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

RUNX family transcription factor 1

involved_in

(PMID:18258917)

NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839

RUNX3

RUNX family transcription factor 3

involved_in

(PMID:18258917)

positive regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SART1

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

involved_in

GO_REF:0000107

NCBI chr18:51,297,419...51,313,804
Ensembl chr18:51,297,419...51,313,793

TNFSF9

TNF superfamily member 9

NCBI chr20:53,680,882...53,682,521
Ensembl chr20:53,679,880...53,682,706

positive regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGER

advanced glycosylation end-product specific receptor

involved_in

GO_REF:0000107

NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129

CD40 ligand

NCBI chr X:107,001,421...107,023,007
Ensembl chr X:107,010,890...107,023,006

HMGB1

high mobility group box 1

involved_in

GO_REF:0000107

NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165

LGALS1

galectin 1

NOT|involved_in

(PMID:16116184)

PMID:16116184

NCBI chr10:26,932,351...26,935,580
Ensembl chr10:26,932,301...26,935,646

LGALS3

galectin 3

NOT|involved_in

(PMID:16116184)

PMID:16116184

NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705

galectin 9

involved_in

(PMID:16116184)

PMID:16116184

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:47,290,696...47,329,342
Ensembl chr24:47,292,684...47,329,570

positive regulation of eosinophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL5

interleukin 5

PMID:10529595 PMID:10727846

RGD

RGD:2303509 RGD:2303750

NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269

TRIB1

tribbles pseudokinase 1

involved_in

(PMID:23515163)

CACAO

PMID:23515163

NCBI chr13:23,337,788...23,346,304
Ensembl chr13:23,337,788...23,346,304

positive regulation of gamma-delta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LCK

LCK proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567

LEF1

lymphoid enhancer binding factor 1

involved_in

GO_REF:0000107

NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019

LOC100687459

GTPase IMAP family member 5

NCBI chr16:14,887,308...14,895,522

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

PTPRC

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124

SOX13

SRY-box transcription factor 13

involved_in

GO_REF:0000107

NCBI chr38:702,974...721,340
Ensembl chr38:523,481...720,195

SOX4

SRY-box transcription factor 4

involved_in

GO_REF:0000107

NCBI chr35:20,098,783...20,101,357
Ensembl chr35:20,099,773...20,101,154

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485

SYK

spleen associated tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

positive regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EVI2B

ecotropic viral integration site 2B

involved_in

(PMID:28186500)

PMID:28186500

NCBI chr 9:41,526,232...41,538,453
Ensembl chr 9:41,535,738...41,537,108

GFI1B

growth factor independent 1B transcriptional repressor

involved_in

(PMID:17707228)

PMID:17707228

NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812

HAX1

HCLS1 associated protein X-1

involved_in

(PMID:23001182)

PMID:23001182

NCBI chr 7:42,969,711...42,972,783
Ensembl chr 7:42,969,713...42,972,710

HCLS1

hematopoietic cell-specific Lyn substrate 1

involved_in

GO_REF:0000107

NCBI chr33:24,901,023...24,925,710
Ensembl chr33:24,901,287...24,922,923

LEF1

lymphoid enhancer binding factor 1

involved_in

GO_REF:0000107

NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019

MIR223

microRNA mir-223

acts_upstream_of_or_within

(PMID:18278031)

PMID:18278031

NCBI chr X:50,838,131...50,838,233
Ensembl chr X:50,838,131...50,838,233

MIR486

microRNA mir-486

involved_in

(PMID:25857263)

PMID:25857263

NCBI chr16:23,958,963...23,959,026
Ensembl chr16:23,958,963...23,959,026

RUNX family transcription factor 1

involved_in

GO_REF:0000107

NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839

TESC

tescalcin

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr26:13,645,513...13,700,521
Ensembl chr26:13,645,511...13,689,367

positive regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

PRKDC

protein kinase, DNA-activated, catalytic subunit

involved_in

ISS

GO_REF:0000024

NCBI chr29:24,904...243,926
Ensembl chr29:35,007...243,895

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485

XRCC6

X-ray repair cross complementing 6

involved_in

(PMID:32103174)

PMID:32103174

NCBI chr10:23,637,905...23,661,618
Ensembl chr10:23,638,237...23,661,480

positive regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASXL2

ASXL transcriptional regulator 2

acts_upstream_of_or_within

(PMID:21490954)

PMID:21490954

NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691

CASP8

caspase 8

involved_in

GO_REF:0000107

NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822

CRSP-3

calcitonin receptor-stimulating peptide 3

involved_in

(PMID:10822112)

PMID:10822112

NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645

CSF1

colony stimulating factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371

FADD

Fas associated via death domain

involved_in

GO_REF:0000107

NCBI chr18:48,087,447...48,094,497

HCLS1

hematopoietic cell-specific Lyn substrate 1

involved_in

GO_REF:0000107

NCBI chr33:24,901,023...24,925,710
Ensembl chr33:24,901,287...24,922,923

HSF1

heat shock transcription factor 1

involved_in

GO_REF:0000107

NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252

ID2

inhibitor of DNA binding 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:5,956,924...5,958,833

IL34

interleukin 34

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:76,601,310...76,612,665
Ensembl chr 5:76,555,214...76,625,012

LIF

LIF interleukin 6 family cytokine

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr26:23,400,226...23,418,538
Ensembl chr26:23,403,364...23,406,851

LOC102151783

inhibitor of DNA binding 2

acts_upstream_of_or_within

(PMID:15616565)

PMID:15616565

NCBI chr10:54,954,852...54,957,116

MIR145

microRNA mir-145

acts_upstream_of

(PMID:30634164)

PMID:30634164

NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210

PRKCA

protein kinase C alpha

involved_in

(PMID:9508782)

PMID:9508782

NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630

RB1

RB transcriptional corepressor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726

RIPK1

receptor interacting serine/threonine kinase 1

involved_in

GO_REF:0000107

NCBI chr35:3,367,796...3,407,631
Ensembl chr35:3,263,226...3,405,883

ROR2

receptor tyrosine kinase like orphan receptor 2

NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151

TRIB1

tribbles pseudokinase 1

involved_in

(PMID:23515163)

CACAO

PMID:23515163

NCBI chr13:23,337,788...23,346,304
Ensembl chr13:23,337,788...23,346,304

positive regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ITGAM

integrin subunit alpha M

involved_in

(PMID:9862668)

PMID:9862668

NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286

PLA2G3

phospholipase A2 group III

involved_in

GO_REF:0000107

NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

positive regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DLA-DRA

MHC class II DR alpha chain

involved_in

GO_REF:0000107

NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975

MHC class II DLA DRB1 beta chain

involved_in

(PMID:27591323)

PMID:27591323

NCBI chr12:2,151,409...2,164,564

IL23A

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

LOC609365

CD46 molecule, complement regulatory protein-like

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr 7:6,602,762...6,646,561

PCK1

phosphoenolpyruvate carboxykinase 1

involved_in

GO_REF:0000107

NCBI chr24:42,538,858...42,544,200
Ensembl chr24:42,538,882...42,544,198

TNF superfamily member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of microglia differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B9D2

B9 domain containing 2

involved_in

(PMID:29909984)

PMID:29909984

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

TGFB1

transforming growth factor beta 1

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885

positive regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACIN1

apoptotic chromatin condensation inducer 1

involved_in

(PMID:12393560)

PMID:12393560

NCBI chr 8:3,370,469...3,405,710
Ensembl chr 8:3,371,004...3,405,682

CD4

CD4 molecule

involved_in

GO_REF:0000107

NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771

CD74

CD74 molecule

involved_in

GO_REF:0000107

NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151

CSF1

colony stimulating factor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371

DCSTAMP

dendrocyte expressed seven transmembrane protein

involved_in

GO_REF:0000107

NCBI chr13:5,542,474...5,559,433
Ensembl chr13:5,542,425...5,571,968

MHC class II DLA DRB1 beta chain

involved_in

(PMID:24942581)

CAFA

PMID:24942581

NCBI chr12:2,151,409...2,164,564

FES

FES proto-oncogene, tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 3:53,346,975...53,356,547
Ensembl chr 3:53,347,012...53,356,516

IL34

interleukin 34

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:76,601,310...76,612,665
Ensembl chr 5:76,555,214...76,625,012

JUN

Jun proto-oncogene, AP-1 transcription factor subunit

murine WEHI-3B D+ cells with or without retinoic acid

RGD

PMID:7947389

RGD:2291846

NCBI chr 5:50,966,698...50,968,939

LOC479600

beta-catenin-interacting protein 1

involved_in

GO_REF:0000107

NCBI chr 5:62,937,154...63,093,083
Ensembl chr 5:62,938,511...63,093,275

ZFP36L1

ZFP36 ring finger protein like 1

involved_in

GO_REF:0000107

NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514

positive regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD101

CD101 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:54,391,572...54,427,350
Ensembl chr17:54,392,165...54,425,620

IL3

interleukin 3

acts_upstream_of_or_within

(PMID:1375116), (PMID:7690439)

PMID:1375116 PMID:7690439

NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668

KITLG

KIT ligand

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr15:29,591,068...29,671,985
Ensembl chr15:29,591,170...29,671,974

positive regulation of natural killer cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AXL

AXL receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 1:112,699,679...112,727,434
Ensembl chr 1:112,700,365...112,726,960

FLT3LG

fms related receptor tyrosine kinase 3 ligand

acts_upstream_of_or_within

(PMID:14607906)

PMID:14607906

NCBI chr 1:107,015,222...107,025,181
Ensembl chr 1:107,015,223...107,024,708

GAS6

growth arrest specific 6

involved_in

GO_REF:0000107

NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875

IL15

interleukin 15

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:1,339,607...1,364,762
Ensembl chr19:1,339,967...1,364,762

IL15RA

interleukin 15 receptor subunit alpha

acts_upstream_of_or_within

(PMID:14607906)

PMID:14607906

NCBI chr 2:29,981,385...30,034,364
Ensembl chr 2:29,981,234...30,038,945

IL21

interleukin 21

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266

RASGRP1

RAS guanyl releasing protein 1

involved_in

GO_REF:0000107

NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485

TOX

thymocyte selection associated high mobility group box

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:9,542,471...9,841,759
Ensembl chr29:9,544,561...9,842,034

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr 8:38,933,721...38,959,306
Ensembl chr 8:38,933,805...38,959,306

positive regulation of neutrophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EVI2B

ecotropic viral integration site 2B

involved_in

IBA

GO_Central

GO_REF:0000033

NCBI chr 9:41,526,232...41,538,453
Ensembl chr 9:41,535,738...41,537,108

IKZF1

IKAROS family zinc finger 1

acts_upstream_of_or_within

(PMID:12406904)

PMID:12406904

NCBI chr18:1,661,851...1,750,987
Ensembl chr18:1,661,690...1,770,768

positive regulation of NK T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AP3B1

adaptor related protein complex 3 subunit beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:28,481,974...28,748,095
Ensembl chr 3:28,481,038...28,751,258

AP3D1

adaptor related protein complex 3 subunit delta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:56,893,479...56,932,460
Ensembl chr20:56,893,535...56,931,830

CD1D

CD1d molecule

acts_upstream_of_or_within

(PMID:9133426)
(PMID:10201995)

PMID:9133426 PMID:10201995

NCBI chr38:23,489,169...23,491,712

TGFBR2

transforming growth factor beta receptor 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636

ZBTB16

zinc finger and BTB domain containing 16

involved_in

GO_REF:0000107

NCBI chr 5:19,082,594...19,284,360
Ensembl chr 5:19,087,154...19,267,628

positive regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GPR68

G protein-coupled receptor 68

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:62,090,050...62,108,922
Ensembl chr 8:62,092,135...62,093,217

NINJ1

ninjurin 1

involved_in

(PMID:30700695)

PMID:30700695

NCBI chr 1:98,566,520...98,576,668
Ensembl chr 1:98,567,680...98,576,657

SLC9B2

solute carrier family 9 member B2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr32:24,354,741...24,419,198
Ensembl chr32:24,360,050...24,417,372

TNFSF11

TNF superfamily member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645

TYROBP

transmembrane immune signaling adaptor TYROBP

involved_in

(PMID:14969392)

PMID:14969392

NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325

positive regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASXL2

ASXL transcriptional regulator 2

acts_upstream_of_or_within

(PMID:21490954)

PMID:21490954

NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691

carbonic anhydrase 2

NCBI chr29:31,959,225...31,975,309
Ensembl chr29:31,935,172...31,980,579

CCL5

C-C motif chemokine ligand 5

NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852

CCR1

chemokine (C-C motif) receptor 1

involved_in

GO_REF:0000107

NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958

CREB1

cAMP responsive element binding protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556

CSF1

colony stimulating factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371

CSF1R

colony stimulating factor 1 receptor

NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510

EEIG1

estrogen-induced osteoclastogenesis regulator 1

involved_in

GO_REF:0000107

NCBI chr 9:55,449,384...55,483,472
Ensembl chr 9:55,449,627...55,480,653

FOS

Fos proto-oncogene, AP-1 transcription factor subunit

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467

GNAS

GNAS complex locus

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657

GSK3B

glycogen synthase kinase 3 beta

NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666

IFNG

interferon gamma

involved_in

GO_REF:0000107

NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698

IL12B

interleukin 12B

involved_in

GO_REF:0000107

NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228

IL17A

interleukin 17A

involved_in

(PMID:17888176)

PMID:17888176

NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513

IL20

interleukin 20

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:6,019,879...6,022,707
Ensembl chr 7:6,019,442...6,023,219

IL23A

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

KLF10

KLF transcription factor 10

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr13:4,216,745...4,223,708
Ensembl chr13:4,218,084...4,223,691

LOC119877838

transmembrane 4 L6 family member 19-like

involved_in

GO_REF:0000107

LOC480600

chemokine (C-C motif) ligand 3

NCBI chr 9:37,708,561...37,710,209
Ensembl chr 9:37,676,966...37,710,209

NEDD9

neural precursor cell expressed, developmentally down-regulated 9

involved_in

GO_REF:0000107

NCBI chr35:10,852,334...11,033,656
Ensembl chr35:10,854,295...10,964,650

NOTCH2

notch receptor 2

involved_in

GO_REF:0000107

NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857

OCSTAMP

osteoclast stimulatory transmembrane protein

involved_in

GO_REF:0000107

NCBI chr24:33,796,582...33,802,385
Ensembl chr24:33,796,027...33,802,270

POU4F1

POU class 4 homeobox 1

involved_in

GO_REF:0000107

NCBI chr22:31,992,657...31,997,066

POU4F2

POU class 4 homeobox 2

involved_in

GO_REF:0000107

NCBI chr15:45,030,818...45,034,446
Ensembl chr15:45,031,094...45,032,784

PPARGC1B

PPARG coactivator 1 beta

involved_in

GO_REF:0000107

NCBI chr 4:59,167,041...59,278,977
Ensembl chr 4:59,174,604...59,279,464

PPP3CA

protein phosphatase 3 catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688

RPTOR

regulatory associated protein of MTOR complex 1

involved_in

(PMID:27879318)

PMID:27879318

NCBI chr 9:1,012,512...1,345,872
Ensembl chr 9:1,013,603...1,344,148

TMEM64

transmembrane protein 64

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr29:36,005,600...36,030,366
Ensembl chr29:35,870,805...36,030,375

TNF

tumor necrosis factor

involved_in

GO_REF:0000107

NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425

TNFRSF11A

TNF receptor superfamily member 11a

involved_in

GO_REF:0000107

NCBI chr 1:14,504,595...14,555,956
Ensembl chr 1:14,503,033...14,556,041

TNFSF11

TNF superfamily member 11

acts_upstream_of_or_within
involved_in

ISO
IEA
IBA

RGD
Ensembl
GO_Central

PMID:11092398

GO_REF:0000033 GO_REF:0000107 RGD:730134

NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645

TRAF6

TNF receptor associated factor 6

involved_in

GO_REF:0000107

NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641

positive regulation of plasma cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DDRGK1

DDRGK domain containing 1

involved_in

GO_REF:0000107

NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157

IL10

interleukin 10

acts_upstream_of

GO_REF:0000107

NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057

IL2

interleukin 2

acts_upstream_of

GO_REF:0000107

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

XBP1

X-box binding protein 1

involved_in

GO_REF:0000107

NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105

positive regulation of pro-T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr 8:38,933,721...38,959,306
Ensembl chr 8:38,933,805...38,959,306

positive regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AMBRA1

autophagy and beclin 1 regulator 1

involved_in

GO_REF:0000107

NCBI chr18:42,903,815...43,073,918
Ensembl chr18:42,932,513...43,072,827

B9D2

B9 domain containing 2

involved_in

(PMID:25065622)

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

BCL6 transcription repressor

involved_in

GO_REF:0000107

NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704

CARMIL2

capping protein regulator and myosin 1 linker 2

acts_upstream_of_or_within

(PMID:23793062)

PMID:23793062

NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152

DUSP10

dual specificity phosphatase 10

involved_in

GO_REF:0000107

NCBI chr38:16,196,354...16,233,640
Ensembl chr38:16,196,635...16,231,315

FOXO3

forkhead box O3

involved_in

GO_REF:0000107

NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198

forkhead box P3

acts_upstream_of_or_within
involved_in

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

interleukin 2

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

IL4I1

interleukin 4 induced 1

involved_in

GO_REF:0000107

NCBI chr 1:106,636,282...106,673,438
Ensembl chr 1:106,657,477...106,673,422

KAT5

lysine acetyltransferase 5

involved_in

GO_REF:0000107

NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699

galectin 9

involved_in

(PMID:25065622)

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

LOC100855640

butyrophilin subfamily 2 member A2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr35:24,251,221...24,265,040
Ensembl chr35:24,251,799...24,262,496

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:20935202), (PMID:22387553)

PMID:20935202 PMID:22387553

NCBI chr 1:102,779,562...102,786,924

LOC490269

complement receptor type 2

involved_in

(PMID:25742728)

PMID:25742728

NCBI chr 7:6,456,238...6,480,672

LOC609365

CD46 molecule, complement regulatory protein-like

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr 7:6,602,762...6,646,561

microRNA mir-214

NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670

receptor transporter protein 2

involved_in

GO_REF:0000107

NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:22387553)

PMID:22387553

NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557

SOX12

SRY-box transcription factor 12

involved_in

GO_REF:0000107

NCBI chr24:20,509,931...20,515,013
Ensembl chr24:20,513,567...20,514,532

TGFB1

transforming growth factor beta 1

involved_in

GO_REF:0000107

NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885

VSIR

V-set immunoregulatory receptor

involved_in

GO_REF:0000107

NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687

positive regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

BAD

BCL2 associated agonist of cell death

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405

CD27

CD27 molecule

involved_in

InterPro

GO_REF:0000002

NCBI chr27:38,534,704...38,537,806
Ensembl chr27:38,534,707...38,537,604

CD74

CD74 molecule

acts_upstream_of_or_within

(PMID:7679955), (PMID:8598040)
(PMID:9432982)

PMID:7679955 PMID:8598040 PMID:9432982

NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151

CYLD

CYLD lysine 63 deubiquitinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175

DLA-DMA

major histocompatibility complex, class II, DM alpha

acts_upstream_of_or_within

(PMID:8598040)
(PMID:8638109)
(PMID:8598041), (PMID:9432982)

PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982

NCBI chr12:2,516,974...2,534,085
Ensembl chr12:2,503,325...2,533,990

DLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:2,221,181...2,227,600
Ensembl chr12:2,221,137...2,227,600

GATA3

GATA binding protein 3

involved_in

GO_REF:0000107

NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760

IL12A

interleukin 12A

acts_upstream_of_or_within

(PMID:22968459)

PMID:22968459

NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550

IL1RL2

interleukin 1 receptor like 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:40,776,670...40,817,263
Ensembl chr10:40,778,590...40,816,044

interleukin 2

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

IL2RA

interleukin 2 receptor subunit alpha

NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643

IL36B

interleukin 36 beta

acts_upstream_of_or_within
involved_in

ISO
IBA

(PMID:22968459)

MGI
GO_Central

PMID:22968459

GO_REF:0000033

NCBI chr17:37,159,276...37,165,841
Ensembl chr17:37,159,434...37,165,423

IL4

interleukin 4

involved_in

(PMID:20554961)

PMID:20554961

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

IL7

interleukin 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737

LOC491316

midkine

involved_in

(PMID:28183532)

PMID:28183532

NCBI chr 9:55,100,491...55,101,081

PIK3R6

phosphoinositide-3-kinase regulatory subunit 6

involved_in

GO_REF:0000107

NCBI chr 5:33,472,240...33,528,369
Ensembl chr 5:33,472,771...33,528,400

PTPRC

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124

RAG1

recombination activating 1

involved_in

GO_REF:0000107

NCBI chr18:31,628,231...31,639,980
Ensembl chr18:31,630,737...31,641,660

RHOH

ras homolog family member H

involved_in

GO_REF:0000107

NCBI chr 3:72,272,446...72,277,015
Ensembl chr 3:72,276,418...72,276,993

WNT10B

Wnt family member 10B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr27:5,599,905...5,605,506
Ensembl chr27:5,601,089...5,605,501

XBP1

X-box binding protein 1

involved_in

GO_REF:0000107

NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105

ZAP70

zeta chain of T cell receptor associated protein kinase 70

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr 8:38,933,721...38,959,306
Ensembl chr 8:38,933,805...38,959,306

ZMIZ1

zinc finger MIZ-type containing 1

involved_in

GO_REF:0000107

NCBI chr 4:28,807,368...29,035,946
Ensembl chr 4:28,854,908...29,045,986

positive regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

ADAM8

ADAM metallopeptidase domain 8

involved_in

GO_REF:0000107

NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747

EGR3

early growth response 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr25:34,591,691...34,597,144
Ensembl chr25:34,591,863...34,594,346

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:55,480,846...55,488,485
Ensembl chr X:55,481,092...55,484,751

IL7R

interleukin 7 receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:72,633,528...72,668,242
Ensembl chr 4:72,636,325...72,668,300

RASGRP1

RAS guanyl releasing protein 1

involved_in

GO_REF:0000107

NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

TESPA1

thymocyte expressed, positive selection associated 1

involved_in

(PMID:22561606)

PMID:22561606

NCBI chr27:424,836...460,114
Ensembl chr27:424,715...460,097

VNN1

vanin 1

involved_in

(PMID:8934567)

PMID:8934567

NCBI chr 1:25,678,039...25,704,579
Ensembl chr 1:25,678,042...25,696,807

positive regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA1

annexin A1

involved_in

GO_REF:0000107

NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011

CCL19

C-C motif chemokine ligand 19

involved_in

(PMID:15845453)

PMID:15845453

NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365

HLX

H2.0 like homeobox

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152

RIPK2

receptor interacting serine/threonine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333

SOCS5

suppressor of cytokine signaling 5

involved_in

GO_REF:0000107

NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452

positive regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MALT1

MALT1 paracaspase

involved_in

GO_REF:0000107

NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927

MIR326

microRNA mir-326

acts_upstream_of_or_within

(PMID:19838199)

PMID:19838199

NCBI chr21:23,240,463...23,240,553
Ensembl chr21:23,240,463...23,240,553

NFKBID

NFKB inhibitor delta

involved_in

(PMID:25282160)

PMID:25282160

NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325

NFKBIZ

NFKB inhibitor zeta

involved_in

GO_REF:0000107

NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561

NLRP3

NLR family pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059

positive regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BRD2

bromodomain containing 2

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr12:2,534,034...2,546,029
Ensembl chr12:2,534,034...2,546,029

BRD4

bromodomain containing 4

involved_in

(PMID:28262505)

PMID:28262505

NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608

EP300

E1A binding protein p300

involved_in

GO_REF:0000107

NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396

IL23A

interleukin 23 subunit alpha

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

OPA1

OPA1 mitochondrial dynamin like GTPase

involved_in

(PMID:36171294)

PMID:36171294

NCBI chr23:52,068,123...52,154,410
Ensembl chr23:52,068,118...52,151,593

positive regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL18

interleukin 18

involved_in

GO_REF:0000107

NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348

IL4R

interleukin 4 receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291

IL6

interleukin 6

acts_upstream_of_or_within

(PMID:12594267)

PMID:12594267

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

NLRP3

NLR family pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059

PRKCZ

protein kinase C zeta

involved_in

GO_REF:0000107

NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664

RARA

retinoic acid receptor alpha

involved_in

GO_REF:0000107

NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459

TNF superfamily member 4

involved_in

(PMID:18354165)

PMID:18354165

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SHB

SH2 domain containing adaptor protein B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325

regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANKLE1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr20:45,461,135...45,465,922
Ensembl chr20:45,461,676...45,465,417

regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANKLE1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr20:45,461,135...45,465,922
Ensembl chr20:45,461,676...45,465,417

CARD11

caspase recruitment domain family member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094

CD24

CD24 molecule

acts_upstream_of_or_within

(PMID:7795661), (PMID:9028339)

PMID:7795661 PMID:9028339

NCBI chr12:64,239,957...64,245,114

CYLD

CYLD lysine 63 deubiquitinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175

FAS

Fas cell surface death receptor

acts_upstream_of_or_within

(PMID:6610701)

PMID:6610701

NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321

FCRL3

Fc receptor like 3

involved_in

(PMID:23857366)

PMID:23857366

NCBI chr 7:40,599,319...40,625,939

IKZF3

IKAROS family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr 9:22,643,482...22,733,988
Ensembl chr 9:22,643,640...22,728,385

MIR150

microRNA mir-150

acts_upstream_of_or_within

(PMID:17927961)

PMID:17927961

NCBI chr 1:106,998,756...106,998,812
Ensembl chr 1:106,998,756...106,998,812

NFAM1

NFAT activating protein with ITAM motif 1

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:15143214)

InterPro
MGI

PMID:15143214

GO_REF:0000002

NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565

PTPN6

protein tyrosine phosphatase non-receptor type 6

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937

SLAMF8

SLAM family member 8

involved_in

(PMID:11313408)

PMID:11313408

NCBI chr38:22,299,455...22,307,090
Ensembl chr38:22,300,128...22,307,096

TLR9

toll like receptor 9

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114

ZFP36L1

ZFP36 ring finger protein like 1

involved_in

GO_REF:0000107

NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514

ZFP36L2

ZFP36 ring finger protein like 2

involved_in

GO_REF:0000107

NCBI chr10:45,746,952...45,751,268
Ensembl chr10:45,748,936...45,751,250

regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SH3RF1

SH3 domain containing ring finger 1

involved_in

(PMID:27084103)

PMID:27084103

NCBI chr25:20,025,920...20,208,470
Ensembl chr25:20,015,915...20,205,946

regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KCNK18

potassium two pore domain channel subfamily K member 18

involved_in

GO_REF:0000107

NCBI chr28:27,694,532...27,707,607
Ensembl chr28:27,694,532...27,706,453

regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CEBPB

CCAAT enhancer binding protein beta

involved_in

GO_REF:0000107

NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656

DLA88

MHC class I DLA-88

involved_in

(PMID:20008523)

PMID:20008523

NCBI chr12:892,442...895,691
Ensembl chr12:892,388...1,021,690

regulation of extrathymic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PRDM1

PR/SET domain 1

involved_in

GO_REF:0000107

NCBI chr12:63,454,242...63,495,278
Ensembl chr12:63,470,974...63,495,579

zinc finger protein 683

involved_in

GO_REF:0000107

NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605

regulation of gamma-delta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EGR3

early growth response 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr25:34,591,691...34,597,144
Ensembl chr25:34,591,863...34,594,346

RORC

RAR related orphan receptor C

acts_upstream_of_or_within

(PMID:21737317)

PMID:21737317

NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453

SOX13

SRY-box transcription factor 13

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr38:702,974...721,340
Ensembl chr38:523,481...720,195

TCF7

transcription factor 7

involved_in

(PMID:23562159)

PMID:23562159

NCBI chr11:22,313,113...22,346,221
Ensembl chr11:22,313,105...22,344,004

regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RARA

retinoic acid receptor alpha

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459

RBP1

retinol binding protein 1

acts_upstream_of_or_within

(PMID:11222375)

PMID:11222375

NCBI chr23:35,677,844...35,698,194
Ensembl chr23:35,679,176...35,698,363

regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IKZF3

IKAROS family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr 9:22,643,482...22,733,988
Ensembl chr 9:22,643,640...22,728,385

NDFIP1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:36,978,148...37,065,247
Ensembl chr 2:36,961,024...37,064,303

RNF41

ring finger protein 41

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:512,650...521,293
Ensembl chr10:514,635...542,395

regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

QKI

QKI, KH domain containing RNA binding

involved_in

GO_REF:0000107

NCBI chr 1:51,800,294...51,956,891
Ensembl chr 1:51,800,309...51,952,714

regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TAL1

TAL bHLH transcription factor 1, erythroid differentiation factor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr15:13,446,752...13,462,038
Ensembl chr15:13,449,481...13,462,047

regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BCL6 transcription repressor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704

receptor transporter protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428

regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FOXP1

forkhead box P1

involved_in

GO_REF:0000107

NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397

regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NDFIP1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:36,978,148...37,065,247
Ensembl chr 2:36,961,024...37,064,303

regulation of natural killer cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

galectin 9

involved_in

(PMID:23408620)

PMID:23408620

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

PRDM1

PR/SET domain 1

involved_in

GO_REF:0000107

NCBI chr12:63,454,242...63,495,278
Ensembl chr12:63,470,974...63,495,579

zinc finger protein 683

involved_in

GO_REF:0000107

NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605

regulation of natural killer cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

zinc finger protein 683

involved_in

GO_REF:0000107

NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605

regulation of NK T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PRDM1

PR/SET domain 1

involved_in

GO_REF:0000107

NCBI chr12:63,454,242...63,495,278
Ensembl chr12:63,470,974...63,495,579

zinc finger protein 683

involved_in

GO_REF:0000107

NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605

regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APC

APC regulator of WNT signaling pathway

acts_upstream_of_or_within

(PMID:15802266)

PMID:15802266

NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993

CEBPB

CCAAT enhancer binding protein beta

involved_in

GO_REF:0000107

NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656

CTNNB1

catenin beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927

ESRRA

estrogen related receptor alpha

NCBI chr18:52,755,547...52,762,938
Ensembl chr18:52,756,344...52,763,355

FGFR3

fibroblast growth factor receptor 3

acts_upstream_of_or_within

(PMID:20053668)

PMID:20053668

NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896

FSHB

follicle stimulating hormone subunit beta

acts_upstream_of_or_within

(PMID:16630814)

PMID:16630814

NCBI chr21:50,279,320...50,282,843
Ensembl chr21:50,280,208...50,282,680

FSHR

follicle stimulating hormone receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:50,765,591...50,938,643
Ensembl chr10:50,770,995...50,938,474

MITF

melanocyte inducing transcription factor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:21,772,147...21,873,545
Ensembl chr20:21,612,927...21,870,578

MTOR

mechanistic target of rapamycin kinase

involved_in

GO_REF:0000107

NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114

PRXL2A

peroxiredoxin like 2A

involved_in

(PMID:19951071)

PMID:19951071

NCBI chr 4:29,539,182...29,559,353
Ensembl chr 4:29,538,781...29,558,961

RASSF2

Ras association domain family member 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:16,736,786...16,779,910
Ensembl chr24:16,736,962...16,781,569

TFE3

transcription factor binding to IGHM enhancer 3

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:11930005)

InterPro
MGI

PMID:11930005

GO_REF:0000002

NCBI chr X:42,181,639...42,192,709
Ensembl chr X:42,183,037...42,193,892

TNF

tumor necrosis factor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425

TNFSF11

TNF superfamily member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645

UBASH3B

ubiquitin associated and SH3 domain containing B

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675

ZBTB7A

zinc finger and BTB domain containing 7A

NCBI chr20:55,517,531...55,527,071
Ensembl chr20:55,505,916...55,523,736

regulation of positive thymic T cell selection

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FOXN1

forkhead box N1

involved_in

GO_REF:0000107

NCBI chr 9:42,734,228...42,749,856
Ensembl chr 9:42,735,656...42,748,632

TOX

thymocyte selection associated high mobility group box

involved_in

GO_REF:0000107

NCBI chr29:9,542,471...9,841,759
Ensembl chr29:9,544,561...9,842,034

regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B9D2

B9 domain containing 2

acts_upstream_of_or_within

(PMID:21245484)

PMID:21245484

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

CD28

CD28 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854

DICER1

dicer 1, ribonuclease III

acts_upstream_of_or_within

(PMID:18725527)

PMID:18725527

NCBI chr 8:63,970,245...64,029,438
Ensembl chr 8:63,972,027...64,019,879

DROSHA

drosha ribonuclease III

acts_upstream_of_or_within

GO_REF:0000107

FANCA

FA complementation group A

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:63,778,149...63,838,869
Ensembl chr 5:63,778,212...63,838,823

FANCD2

FA complementation group D2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:8,240,270...8,297,269
Ensembl chr20:8,240,311...8,297,568

KAT2A

lysine acetyltransferase 2A

involved_in

GO_REF:0000107

NCBI chr 9:20,778,434...20,787,057
Ensembl chr 9:20,779,042...20,787,067

LCK

LCK proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567

SH2B3

SH2B adaptor protein 3

NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204

TGFB1

transforming growth factor beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885

regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

BRAF

B-Raf proto-oncogene, serine/threonine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906

CARD11

caspase recruitment domain family member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094

CCR2

C-C motif chemokine receptor 2

involved_in

GO_REF:0000107

NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698

CRTAM

cytotoxic and regulatory T cell molecule

involved_in

GO_REF:0000107

NCBI chr 5:11,458,360...11,485,469
Ensembl chr 5:11,458,008...11,485,448

CYP26B1

cytochrome P450 family 26 subfamily B member 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:50,633,397...50,653,882
Ensembl chr17:50,633,413...50,653,894

DLA-DOA

HLA class II histocompatibility antigen, DO alpha chain-like

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:2,563,673...2,568,328
Ensembl chr12:2,563,673...2,568,328

FAS

Fas cell surface death receptor

acts_upstream_of_or_within

(PMID:6610701)

PMID:6610701

NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321

IL15

interleukin 15

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:1,339,607...1,364,762
Ensembl chr19:1,339,967...1,364,762

LOC100683783

double homeobox protein 4C-like

acts_upstream_of_or_within

(PMID:17911620)

PMID:17911620

NCBI chr17:64,277,421...64,282,701

METTL3

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

involved_in

(PMID:28792938)

PMID:28792938

NCBI chr15:18,528,755...18,546,303
Ensembl chr15:18,528,772...18,546,531

PRELID1

PRELI domain containing 1

involved_in

GO_REF:0000107

NCBI chr 4:36,051,562...36,055,080
Ensembl chr 4:36,051,879...36,055,043

RAG1

recombination activating 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr18:31,628,231...31,639,980
Ensembl chr18:31,630,737...31,641,660

SLC46A2

solute carrier family 46 member 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:67,297,596...67,305,893
Ensembl chr11:67,297,597...67,305,893

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261

regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

ADRM1

ADRM1 26S proteasome ubiquitin receptor

involved_in

(PMID:21048919)

PMID:21048919

NCBI chr24:46,309,478...46,314,892
Ensembl chr24:46,275,175...46,491,347

ANKLE1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr20:45,461,135...45,465,922
Ensembl chr20:45,461,676...45,465,417

CLPTM1

CLPTM1 regulator of GABA type A receptor forward trafficking

involved_in

GO_REF:0000107

NCBI chr 1:110,471,164...110,500,229
Ensembl chr 1:110,471,559...110,500,175

FOXN1

forkhead box N1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:42,734,228...42,749,856
Ensembl chr 9:42,735,656...42,748,632

galectin 9

NOT|involved_in

(PMID:25065622)

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063

SOS2

SOS Ras/Rho guanine nucleotide exchange factor 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:26,636,849...26,698,837
Ensembl chr 8:26,637,895...26,717,781

ZEB1

zinc finger E-box binding homeobox 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:15,300,401...15,481,535
Ensembl chr 2:15,299,723...15,481,495

regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL27

interleukin 27

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635

regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCL20

C-C motif chemokine ligand 20

NOT|involved_in

(PMID:19050256)

PMID:19050256

NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709

CCR6

C-C motif chemokine receptor 6

NOT|involved_in

(PMID:19050256)

PMID:19050256

NCBI chr 1:54,932,798...54,960,646
Ensembl chr 1:54,932,690...54,959,740

MIR301A

microRNA mir-301a

acts_upstream_of_or_within

(PMID:22517757)

PMID:22517757

NCBI chr 9:33,724,572...33,724,655
Ensembl chr 9:33,724,571...33,724,655

regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DLA-DRA

MHC class II DR alpha chain

involved_in

GO_REF:0000107

NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975

MHC class II DLA DRB1 beta chain

involved_in

(PMID:15322540)

PMID:15322540

NCBI chr12:2,151,409...2,164,564

GATA3

GATA binding protein 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within