regulation of leukocyte differentiation - Ontology Report

GO_REF:0000107

NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506

sonic hedgehog signaling molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

negative regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FLT3

fms related receptor tyrosine kinase 3

acts_upstream_of_or_within

(PMID:16618805)

PMID:16618805

NCBI chr13:9,283,747...9,381,553
Ensembl chr13:27,627,178...27,723,940

HMGB3

high mobility group box 3

acts_upstream_of_or_within

(PMID:12714519)

PMID:12714519

NCBI chr X:140,632,163...140,639,774

ID2

inhibitor of DNA binding 2

acts_upstream_of_or_within

(PMID:18523151)

PMID:18523151

NCBI chr2A:8,681,592...8,684,014
Ensembl chr2A:8,847,776...8,850,720

SFRP1

secreted frizzled related protein 1

involved_in

(PMID:18941195)

PMID:18941195

NCBI chr 8:40,507,027...40,555,053

negative regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBFB

core-binding factor subunit beta

involved_in

(PMID:18258917)

NCBI chr16:47,373,543...47,446,783

HMGB1

high mobility group box 1

involved_in

GO_REF:0000107

NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527

RUNX3

RUNX family transcription factor 3

involved_in

(PMID:18258917)

NCBI chr 1:24,097,321...24,164,065
Ensembl chr 1:25,073,134...25,137,335

negative regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC4A2

solute carrier family 4 member 2

involved_in

(PMID:24515893)

PMID:24515893

NCBI chr 7:142,646,413...142,663,376
Ensembl chr 7:154,799,256...154,815,919

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr16:10,196,432...10,198,205

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729

negative regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

leukocyte immunoglobulin like receptor B4

involved_in

(PMID:16493035)

PMID:16493035

NCBI chr19:51,606,681...51,612,751

negative regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CLEC12A

C-type lectin domain family 12 member A

involved_in

GO_REF:0000107

NCBI chr12:9,999,334...10,056,108
Ensembl chr12:10,248,209...10,272,070

LOC100978774

patr class I histocompatibility antigen, alpha chain G

involved_in

GO_REF:0000107

NCBI chr 6:29,616,091...29,620,270
Ensembl chr 6:30,286,395...30,390,865

LOC103783591

leukocyte immunoglobulin-like receptor subfamily B member 1

involved_in

(PMID:18684926)

PMID:18684926

NCBI chr19:51,561,376...51,578,564

TMEM176A

transmembrane protein 176A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:142,383,001...142,387,407
Ensembl chr 7:154,535,019...154,539,613

TMEM176B

transmembrane protein 176B

involved_in
acts_upstream_of_or_within

GO_REF:0000107 GO_REF:0000118

NCBI chr 7:142,373,598...142,383,646
Ensembl chr 7:154,525,878...154,535,862

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

Ensembl chr20:61,667,319...61,713,895

negative regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

involved_in

GO_REF:0000107

NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885

C1QC

complement C1q C chain

involved_in

GO_REF:0000107

NCBI chr 1:21,828,969...21,833,518
Ensembl chr 1:22,770,582...22,782,176

CEACAM1

CEA cell adhesion molecule 1

involved_in

(PMID:21029969)

PMID:21029969

NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739

CUL4A

cullin 4A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr13:94,350,484...94,409,183
Ensembl chr13:113,428,271...113,472,701

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190

PRDM16

PR/SET domain 16

involved_in

(PMID:12816872)

PMID:12816872

NCBI chr 1:1,730,122...2,100,636
Ensembl chr 1:2,981,667...3,234,251

RARA

retinoic acid receptor alpha

involved_in

(PMID:19917671)

PMID:19917671

NCBI chr17:16,932,485...16,980,958

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

Ensembl chr20:61,667,319...61,713,895

negative regulation of immature T cell proliferation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752

CDKN2A

cyclin dependent kinase inhibitor 2A

involved_in

(PMID:15964995)

HGNC-UCL

PMID:15964995

NCBI chr 9:21,803,862...21,831,322

CLEC4G

C-type lectin domain family 4 member G

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:7,015,848...7,019,396
Ensembl chr19:7,870,730...7,873,631

ERBB2

erb-b2 receptor tyrosine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506

TMEM131L

transmembrane 131 like

involved_in

GO_REF:0000107

NCBI chr 4:145,808,457...145,978,954
Ensembl chr 4:157,630,958...157,802,132

negative regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FBXO7

F-box protein 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224

negative regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

involved_in

GO_REF:0000107

NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885

C1QC

complement C1q C chain

involved_in

GO_REF:0000107

NCBI chr 1:21,828,969...21,833,518
Ensembl chr 1:22,770,582...22,782,176

GATA2

GATA binding protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035

PTPN2

protein tyrosine phosphatase non-receptor type 2

involved_in

GO_REF:0000107

NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570

QKI

QKI, KH domain containing RNA binding

involved_in

(PMID:22398723)

PMID:22398723

NCBI chr 6:161,361,413...161,523,414

TAOK3

TAO kinase 3

involved_in

GO_REF:0000107

NCBI chr12:115,730,619...115,954,149
Ensembl chr12:119,109,642...119,226,502

THOC5

THO complex subunit 5

acts_upstream_of_or_within

(PMID:10597251)

PMID:10597251

NCBI chr22:10,553,665...10,599,948
Ensembl chr22:28,357,644...28,404,346

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

Ensembl chr20:61,667,319...61,713,895

negative regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ZFPM1

zinc finger protein, FOG family member 1

involved_in

(PMID:18063754)

PMID:18063754

NCBI chr16:69,164,299...69,246,136

negative regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGL2

fibrinogen like 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:69,114,082...69,120,575
Ensembl chr 7:82,926,266...82,932,550

LOC100976419

interferon lambda-1

involved_in

GO_REF:0000107

NCBI chr19:36,394,462...36,397,363
Ensembl chr19:44,942,186...44,944,519

negative regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APCS

amyloid P component, serum

involved_in

GO_REF:0000107

NCBI chr 1:134,937,472...134,938,512
Ensembl chr 1:138,734,046...138,735,093

CDK6

cyclin dependent kinase 6

involved_in

(PMID:26542173)

PMID:26542173

NCBI chr 7:84,603,419...84,835,082

GPR68

G protein-coupled receptor 68

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806

HOXA7

homeobox A7

involved_in

GO_REF:0000107

NCBI chr 7:27,799,317...27,802,492
Ensembl chr 7:27,396,898...27,402,142

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190

MYC

MYC proto-oncogene, bHLH transcription factor

involved_in

IEA
ISS

Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

Ensembl chr20:61,667,319...61,713,895

negative regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LYN

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287

NME1

NME/NM23 nucleoside diphosphate kinase 1

NCBI chr17:45,243,588...45,252,135
Ensembl chr17:50,113,622...50,131,636

NME2

NME/NM23 nucleoside diphosphate kinase 2

NCBI chr17:45,255,982...45,261,541

negative regulation of natural killer cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PGLYRP1

peptidoglycan recognition protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:43,033,080...43,037,726
Ensembl chr19:51,569,275...51,573,764

PGLYRP2

peptidoglycan recognition protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:14,999,893...15,012,376
Ensembl chr19:15,986,090...15,997,726

PGLYRP3

peptidoglycan recognition protein 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:128,642,034...128,656,082
Ensembl chr 1:132,270,957...132,283,860

PGLYRP4

peptidoglycan recognition protein 4

acts_upstream_of_or_within

(PMID:20709292)

PMID:20709292

NCBI chr 1:128,681,726...128,700,275
Ensembl chr 1:132,310,256...132,329,013

negative regulation of neutrophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

GO_REF:0000107 GO_REF:0000118

NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190

TRIB1

tribbles pseudokinase 1

involved_in

GO_REF:0000107

NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924

negative regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CLDN18

claudin 18

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:135,037,555...135,061,105
Ensembl chr 3:142,478,031...142,512,548

FBN1

fibrillin 1

involved_in

GO_REF:0000107

NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111

FBXW7

F-box and WD repeat domain containing 7

involved_in

GO_REF:0000107

NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351

LOC103783591

leukocyte immunoglobulin-like receptor subfamily B member 1

involved_in

(PMID:18802077)

PMID:18802077

NCBI chr19:51,561,376...51,578,564

TJP2

tight junction protein 2

acts_upstream_of_or_within

(PMID:22437732)

PMID:22437732

NCBI chr 9:55,536,627...55,690,472
Ensembl chr 9:67,886,421...68,021,189

negative regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CALCA

calcitonin related polypeptide alpha

involved_in

(PMID:10822112)

PMID:10822112

NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267

CEACAM1

CEA cell adhesion molecule 1

acts_upstream_of_or_within

(PMID:25490771)

PMID:25490771

NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739

CTNNB1

catenin beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030

ERFE

erythroferrone

acts_upstream_of

(PMID:34002695)

PMID:34002695

NCBI chr2B:125,390,190...125,401,677

FBN1

fibrillin 1

involved_in

GO_REF:0000107

NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111

FSTL3

follistatin like 3

involved_in

(PMID:15574124)

G protein-coupled receptor 137

involved_in

TreeGrafter

GO_REF:0000118

NCBI chr11:59,627,488...59,646,556
Ensembl chr11:62,985,909...62,990,950

GPR137B

G protein-coupled receptor 137B

involved_in

TreeGrafter

GO_REF:0000118

NCBI chr 1:211,709,507...211,775,846
Ensembl chr 1:216,696,105...216,778,370

GPR55

G protein-coupled receptor 55

involved_in

GO_REF:0000107

NCBI chr2B:118,159,511...118,163,334
Ensembl chr2B:236,958,210...236,959,169

IAPP

islet amyloid polypeptide

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:64,918,000...64,925,191
Ensembl chr12:67,520,986...67,528,103

IFNB1

interferon beta 1

acts_upstream_of_or_within

(PMID:17442941)

PMID:17442941

NCBI chr 9:20,884,742...20,886,317

IFNG

interferon gamma

acts_upstream_of_or_within

(PMID:17442941)

PMID:17442941

NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829

IL4

interleukin 4

acts_upstream_of_or_within

(PMID:12941478), (PMID:17442941)

PMID:12941478 PMID:17442941

NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581

INPP4B

inositol polyphosphate-4-phosphatase type II B

acts_upstream_of_or_within

(PMID:21982707)

PMID:21982707

NCBI chr 4:134,405,934...135,213,851
Ensembl chr 4:145,706,307...146,141,029

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190

leukocyte immunoglobulin like receptor B4

involved_in

(PMID:18802077)

PMID:18802077

NCBI chr19:51,606,681...51,612,751

LOC100991256

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:18802077)

PMID:18802077

NCBI chr19:51,148,567...51,154,764

LOC100992309

C-C motif chemokine 3

involved_in

GO_REF:0000107

NCBI chr17:20,704,738...20,706,641
Ensembl chr17:21,000,709...21,002,610

LRRC17

leucine rich repeat containing 17

involved_in

(PMID:19336404)

PMID:19336404

NCBI chr 7:94,884,624...94,917,576
Ensembl chr 7:107,756,505...107,767,445

MAFB

MAF bZIP transcription factor B

involved_in

GO_REF:0000107

NCBI chr20:37,023,988...37,027,446
Ensembl chr20:38,127,722...38,128,693

NF1

neurofibromin 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

PIAS3

protein inhibitor of activated STAT 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:121,900,224...121,911,513
Ensembl chr 1:113,758,691...113,768,714

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960

SFRP1

secreted frizzled related protein 1

acts_upstream_of_or_within

PMID:14976225 PMID:17540629

(PMID:14976225)

RGD
MGI

RGD:4107086

NCBI chr 8:40,507,027...40,555,053

TCTA

T cell leukemia translocation altered

involved_in

(PMID:19560569)

PMID:19560569

NCBI chr 3:49,340,010...49,344,288

TMEM178A

transmembrane protein 178A

involved_in

(PMID:26644563)

PMID:26644563

NCBI chr2A:39,702,860...39,755,605

TNFAIP6

TNF alpha induced protein 6

involved_in

GO_REF:0000107

NCBI chr2B:38,669,652...38,692,037
Ensembl chr2B:155,933,842...155,956,382

TNFRSF11B

TNF receptor superfamily member 11b

acts_upstream_of_or_within
involved_in

IEA
ISO

(PMID:9168977)

Ensembl
ComplexPortal

PMID:9168977

GO_REF:0000107

NCBI chr 8:115,614,778...115,643,387
Ensembl chr 8:118,134,305...118,162,422

TOB2

transducer of ERBB2, 2

acts_upstream_of_or_within

(PMID:18358842)

PMID:18358842

NCBI chr22:22,329,783...22,344,795

UBASH3B

ubiquitin associated and SH3 domain containing B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:117,489,411...117,647,719
Ensembl chr11:121,410,545...121,563,133

negative regulation of plasma cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BCL6 transcription repressor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124

CR1

complement C3b/C4b receptor 1 (Knops blood group)

acts_upstream_of

(PMID:22962438)

PMID:22962438

NCBI chr 1:183,094,601...183,246,957

negative regulation of positive thymic T cell selection

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PTPN2

protein tyrosine phosphatase non-receptor type 2

involved_in

GO_REF:0000107

NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570

negative regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD44

CD44 molecule (IN blood group)

involved_in

(PMID:25065622)

PMID:25065622

NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009

CTLA4

cytotoxic T-lymphocyte associated protein 4

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498

HSPB1

heat shock protein family B (small) member 1

NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984

IRF1

interferon regulatory factor 1

involved_in

GO_REF:0000107

NCBI chr 5:127,903,887...127,913,843
Ensembl chr 5:134,067,441...134,075,035

LAG3

lymphocyte activating 3

involved_in

GO_REF:0000107

NCBI chr12:6,903,770...6,909,778
Ensembl chr12:6,817,507...6,823,047

MDK

midkine

involved_in

GO_REF:0000107

NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254

TNF superfamily member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845

TUG1

taurine up-regulated 1

negative regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD74

CD74 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334

DTX1

deltex E3 ubiquitin ligase 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:110,661,247...110,702,780
Ensembl chr12:114,046,700...114,085,372

IFNB1

interferon beta 1

involved_in

(PMID:20554961)

PMID:20554961

NCBI chr 9:20,884,742...20,886,317

LOC100972354

interferon alpha-2

involved_in

GO_REF:0000107

NCBI chr 9:21,245,017...21,246,210
Ensembl chr 9:21,863,062...21,863,736

LOC100976419

interferon lambda-1

involved_in

GO_REF:0000107

NCBI chr19:36,394,462...36,397,363
Ensembl chr19:44,942,186...44,944,519

NRARP

NOTCH regulated ankyrin repeat protein

acts_upstream_of_or_within

(PMID:12794108)

PMID:12794108

NCBI chr 9:108,358,959...108,361,586

PRDX2

peroxiredoxin 2

acts_upstream_of_or_within

(PMID:16290204)

PMID:16290204

NCBI chr19:12,359,084...12,363,552
Ensembl chr19:13,103,422...13,107,369

negative regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752

FOXJ1

forkhead box J1

involved_in

GO_REF:0000107

NCBI chr17:70,084,920...70,089,865
Ensembl chr17:75,638,634...75,641,666

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506

NFKBID

NFKB inhibitor delta

acts_upstream_of_or_within

(PMID:11931770)

PMID:11931770

NCBI chr19:32,805,772...32,817,778
Ensembl chr19:41,553,727...41,568,555

RAG2

recombination activating 2

NCBI chr11:36,558,419...36,564,997
Ensembl chr11:36,431,703...36,433,286

sonic hedgehog signaling molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

ZC3H8

zinc finger CCCH-type containing 8

involved_in

GO_REF:0000107

NCBI chr2A:89,750,479...89,800,330
Ensembl chr2A:113,342,973...113,387,110

negative regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

(PMID:24463518)

PMID:24463518

NCBI chr11:2,305,497...2,308,080

IL4R

interleukin 4 receptor

acts_upstream_of_or_within

(PMID:16424184)

PMID:16424184

Ensembl chr16:27,642,702...27,737,445

JAK3

Janus kinase 3

involved_in

(PMID:16020505)

PMID:16020505

NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964

TNF superfamily member 4

involved_in

(PMID:9670042)

PMID:9670042

NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845

negative regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

(PMID:24463518)

PMID:24463518

NCBI chr11:2,305,497...2,308,080

forkhead box P3

involved_in

GO_REF:0000107

NCBI chr X:41,550,462...41,567,492
Ensembl chr X:49,402,652...49,417,029

IL2

interleukin 2

involved_in

GO_REF:0000107

NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984

IL4

interleukin 4

acts_upstream_of_or_within

(PMID:18792410)

PMID:18792410

NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581

platelet factor 4

NCBI chr 4:50,208,806...50,210,570
Ensembl chr 4:56,041,833...56,043,750

RC3H1

ring finger and CCCH-type domains 1

involved_in

GO_REF:0000107

NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402

RC3H2

ring finger and CCCH-type domains 2

involved_in

GO_REF:0000107

NCBI chr 9:93,975,164...94,031,516
Ensembl chr 9:122,313,791...122,365,102

SMAD7

SMAD family member 7

involved_in

(PMID:25642768)

PMID:25642768

NCBI chr18:42,306,324...42,337,214

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729

ZC3H12A

zinc finger CCCH-type containing 12A

involved_in

GO_REF:0000107

NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556

negative regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD69

CD69 molecule

involved_in

GO_REF:0000107

NCBI chr12:9,800,446...9,808,874
Ensembl chr12:10,049,668...10,058,094

JAK3

Janus kinase 3

involved_in

GO_REF:0000107

NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964

LGALS1

galectin 1

involved_in

GO_REF:0000107

NCBI chr22:18,593,154...18,597,432
Ensembl chr22:36,426,228...36,430,356

signal transducer and activator of transcription 5A

involved_in

GO_REF:0000107

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

LOXL3

lysyl oxidase like 3

involved_in

GO_REF:0000107

NCBI chr2A:74,598,870...74,622,502
Ensembl chr2A:76,105,957...76,128,495

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660

TNFSF18

TNF superfamily member 18

involved_in

(PMID:24107315)

PMID:24107315

negative regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA1

annexin A1

involved_in

GO_REF:0000107

NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

(PMID:24463518)

PMID:24463518

NCBI chr11:2,305,497...2,308,080

BCL6 transcription repressor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124

HLX

H2.0 like homeobox

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222

SOCS5

suppressor of cytokine signaling 5

involved_in

(PMID:12242343)

PMID:12242343

NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041

negative regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RC3H1

ring finger and CCCH-type domains 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402

positive regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868

GLI3

GLI family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506

ITPKB

inositol-trisphosphate 3-kinase B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:202,091,263...202,198,880
Ensembl chr 1:207,084,883...207,191,678

LOC100971372

tyrosine-protein kinase ZAP-70

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2A:101,582,567...101,613,175
Ensembl chr2A:98,613,740...98,639,088

NKAP

NFKB activating protein

involved_in

GO_REF:0000107

NCBI chr X:108,988,561...109,006,946
Ensembl chr X:119,384,655...119,402,775

PNP

purine nucleoside phosphorylase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr14:1,343,921...1,351,670
Ensembl chr14:19,396,114...19,403,907

RHOA

ras homolog family member A

involved_in

GO_REF:0000107

NCBI chr 3:49,282,009...49,339,887

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

SYK

spleen associated tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101

positive regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP11C

ATPase phospholipid transporting 11C

involved_in

(PMID:21423173)

PMID:21423173

NCBI chr X:128,880,747...129,085,989
Ensembl chr X:139,132,783...139,334,869

BAD

BCL2 associated agonist of cell death

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257

CD27

CD27 molecule

involved_in

InterPro

GO_REF:0000002

NCBI chr12:6,575,104...6,582,127
Ensembl chr12:6,492,119...6,499,427

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:60,375,815...60,386,936
Ensembl chr X:70,433,360...70,437,590

IL7

interleukin 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:75,254,166...75,337,373
Ensembl chr 8:76,895,095...76,966,918

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

GO_REF:0000107 GO_REF:0000118

NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463

MMP14

matrix metallopeptidase 14

involved_in

GO_REF:0000107

NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881

PCID2

PCI domain containing 2

involved_in

GO_REF:0000107

NCBI chr13:94,319,699...94,350,763
Ensembl chr13:113,388,251...113,419,251

PPP2R3C

protein phosphatase 2 regulatory subunit B''gamma

involved_in
acts_upstream_of_or_within

GO_REF:0000107 GO_REF:0000118

NCBI chr14:15,834,603...15,871,741
Ensembl chr14:34,020,893...34,056,842

SPI1

Spi-1 proto-oncogene

involved_in

GO_REF:0000107

NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259

SYK

spleen associated tyrosine kinase

acts_upstream_of_or_within
involved_in

GO_REF:0000107

NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101

XBP1

X-box binding protein 1

involved_in

GO_REF:0000107

NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943

positive regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD83

CD83 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:13,961,342...13,980,686
Ensembl chr 6:14,330,752...14,349,946

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:41,550,462...41,567,492
Ensembl chr X:49,402,652...49,417,029

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881

SASH3

SAM and SH3 domain containing 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:118,909,980...118,924,779
Ensembl chr X:129,207,049...129,222,342

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr16:10,196,432...10,198,205

TNF superfamily member 4

involved_in

(PMID:20639485)

PMID:20639485

NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:41,550,462...41,567,492
Ensembl chr X:49,402,652...49,417,029

GIMAP5

GTPase, IMAP family member 5

NCBI chr 7:142,319,479...142,326,035

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:60,375,815...60,386,936
Ensembl chr X:70,433,360...70,437,590

KLHL25

kelch like family member 25

involved_in

GO_REF:0000107

NCBI chr15:64,448,130...64,486,254
Ensembl chr15:83,670,090...83,671,859

LOC100987081

HLA class II histocompatibility antigen, DR alpha chain

involved_in

GO_REF:0000107

NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IFNG

interferon gamma

involved_in

GO_REF:0000107

NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829

galectin-9

involved_in

GO_REF:0000107

NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959

LOC117976679

galectin-9B

involved_in

GO_REF:0000107

NCBI chr17:35,781,679...35,790,573

LOC129394382

galectin-9B-like

involved_in

GO_REF:0000107

positive regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBFB

core-binding factor subunit beta

involved_in

(PMID:18258917)

NCBI chr16:47,373,543...47,446,783

leukocyte immunoglobulin like receptor B4

involved_in

(PMID:18420485)

PMID:18420485

NCBI chr19:51,606,681...51,612,751

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881

RUNX3

RUNX family transcription factor 3

involved_in

(PMID:18258917)

NCBI chr 1:24,097,321...24,164,065
Ensembl chr 1:25,073,134...25,137,335

positive regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SART1

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

involved_in

GO_REF:0000107

NCBI chr11:61,326,262...61,343,475
Ensembl chr11:64,654,470...64,670,720

TNFSF9

TNF superfamily member 9

involved_in

ISO
IEA

RGD
TreeGrafter

PMID:19187795

GO_REF:0000118 RGD:2317344

NCBI chr19:5,558,021...5,562,901
Ensembl chr19:6,476,941...6,483,352

positive regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGER

advanced glycosylation end-product specific receptor

involved_in

GO_REF:0000107

NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641

CD40 ligand

NCBI chr X:125,776,138...125,788,820
Ensembl chr X:136,042,849...136,058,202

HMGB1

high mobility group box 1

involved_in

GO_REF:0000107

NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527

LGALS1

galectin 1

NOT|involved_in

(PMID:16116184)

PMID:16116184

NCBI chr22:18,593,154...18,597,432
Ensembl chr22:36,426,228...36,430,356

LGALS3

galectin 3

NOT|involved_in

(PMID:16116184)

PMID:16116184

NCBI chr14:35,715,850...35,732,263
Ensembl chr14:53,990,023...54,006,412

galectin-9

involved_in

GO_REF:0000107

NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959

LOC117976679

galectin-9B

involved_in

GO_REF:0000107

NCBI chr17:35,781,679...35,790,573

LOC129394382

galectin-9B-like

involved_in

GO_REF:0000107

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

GO_REF:0000107

Ensembl chr20:61,667,319...61,713,895

positive regulation of eosinophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL5

interleukin 5

PMID:10529595 PMID:10727846

RGD

RGD:2303509 RGD:2303750

NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675

TRIB1

tribbles pseudokinase 1

involved_in

GO_REF:0000107

NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924

positive regulation of gamma-delta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GIMAP5

GTPase, IMAP family member 5

NCBI chr 7:142,319,479...142,326,035

LCK

LCK proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923

LEF1

lymphoid enhancer binding factor 1

involved_in

GO_REF:0000107

NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881

PTPRC

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994

SOX13

SRY-box transcription factor 13

involved_in

(PMID:23562159)

PMID:23562159

NCBI chr 1:179,675,017...179,730,628
Ensembl chr 1:184,003,907...184,016,504

SOX4

SRY-box transcription factor 4

involved_in

(PMID:23562159)

PMID:23562159

NCBI chr 6:21,422,846...21,427,779

SYK

spleen associated tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101

positive regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EVI2B

ecotropic viral integration site 2B

involved_in

GO_REF:0000107

NCBI chr17:25,484,228...25,495,150
Ensembl chr17:26,229,023...26,230,368

GFI1B

growth factor independent 1B transcriptional repressor

involved_in

(PMID:17707228)

PMID:17707228

NCBI chr 9:104,061,236...104,113,208
Ensembl chr 9:132,692,343...132,742,326

HAX1

HCLS1 associated protein X-1

involved_in

GO_REF:0000107

NCBI chr 1:129,627,564...129,630,920
Ensembl chr 1:133,241,077...133,244,431

HCLS1

hematopoietic cell-specific Lyn substrate 1

involved_in

GO_REF:0000107

NCBI chr 3:118,733,505...118,763,177
Ensembl chr 3:125,642,973...125,669,095

LEF1

lymphoid enhancer binding factor 1

involved_in

GO_REF:0000107

NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980

RUNX1

RUNX family transcription factor 1

involved_in

GO_REF:0000107

NCBI chr21:21,159,586...21,423,946
Ensembl chr21:34,530,956...34,788,544

TESC

tescalcin

involved_in

GO_REF:0000107

NCBI chr12:114,615,155...114,675,932
Ensembl chr12:117,991,047...118,051,346

positive regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881

PRKDC

protein kinase, DNA-activated, catalytic subunit

involved_in

GO_REF:0000107

NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299

XRCC6

X-ray repair cross complementing 6

involved_in

(PMID:32103174)

PMID:32103174

NCBI chr22:22,516,281...22,557,379
Ensembl chr22:40,603,038...40,643,314

positive regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASXL2

ASXL transcriptional regulator 2

acts_upstream_of_or_within

(PMID:21490954)

PMID:21490954

NCBI chr2A:25,730,155...25,880,089
Ensembl chr2A:25,832,527...25,973,659

CALCA

calcitonin related polypeptide alpha

involved_in

(PMID:10822112)

PMID:10822112

NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267

CASP8

caspase 8

involved_in

GO_REF:0000107

NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468

CSF1

colony stimulating factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943

FADD

Fas associated via death domain

involved_in

(PMID:17047155)

PMID:17047155

NCBI chr11:65,300,889...65,305,020

HCLS1

hematopoietic cell-specific Lyn substrate 1

involved_in

GO_REF:0000107

NCBI chr 3:118,733,505...118,763,177
Ensembl chr 3:125,642,973...125,669,095

HSF1

heat shock transcription factor 1

involved_in

GO_REF:0000107

NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866

ID2

inhibitor of DNA binding 2

acts_upstream_of_or_within

(PMID:15616565)

PMID:15616565

NCBI chr2A:8,681,592...8,684,014
Ensembl chr2A:8,847,776...8,850,720

IL34

interleukin 34

involved_in

GO_REF:0000107 GO_REF:0000118

Ensembl chr16:70,480,917...70,494,693

LIF

LIF interleukin 6 family cytokine

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr22:11,276,576...11,282,972
Ensembl chr22:29,078,862...29,095,608

PF4

platelet factor 4

involved_in

GO_REF:0000107

NCBI chr 4:50,208,806...50,210,570
Ensembl chr 4:56,041,833...56,043,750

PRKCA

protein kinase C alpha

involved_in

(PMID:9508782)

PMID:9508782

NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903

RB1

RB transcriptional corepressor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575

RIPK1

receptor interacting serine/threonine kinase 1

involved_in

GO_REF:0000107

NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078

ROR2

receptor tyrosine kinase like orphan receptor 2

NCBI chr 9:62,782,183...63,005,626
Ensembl chr 9:90,851,983...90,965,084

TRIB1

tribbles pseudokinase 1

involved_in

GO_REF:0000107

NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924

positive regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ITGAM

integrin subunit alpha M

involved_in

(PMID:9862668)

PMID:9862668

NCBI chr16:23,634,476...23,707,147
Ensembl chr16:31,630,146...31,702,406

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

PLA2G3

phospholipase A2 group III

involved_in

GO_REF:0000107

NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160

positive regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD46

CD46 molecule

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046

IL23A

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617

LOC100987081

HLA class II histocompatibility antigen, DR alpha chain

involved_in

GO_REF:0000107

NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417

PCK1

phosphoenolpyruvate carboxykinase 1

involved_in

GO_REF:0000107

NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920

TNF superfamily member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845

positive regulation of microglia differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TGFB1

transforming growth factor beta 1

involved_in

GO_REF:0000107

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

positive regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACIN1

apoptotic chromatin condensation inducer 1

involved_in

(PMID:12393560)

PMID:12393560

NCBI chr14:3,878,426...3,915,802
Ensembl chr14:21,975,370...22,012,092

CD4

CD4 molecule

involved_in

GO_REF:0000107

NCBI chr12:6,920,587...6,951,814
Ensembl chr12:6,834,011...6,864,204

CD74

CD74 molecule

involved_in

GO_REF:0000107

NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334

CLSTN1

calsyntenin 1

involved_in

GO_REF:0000107

NCBI chr 1:8,495,571...8,591,613
Ensembl chr 1:9,724,743...9,774,760

CSF1

colony stimulating factor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943

CTNNBIP1

catenin beta interacting protein 1

involved_in

GO_REF:0000107

Ensembl chr 1:9,846,511...9,882,049

DCSTAMP

dendrocyte expressed seven transmembrane protein

involved_in

(PMID:17713547)

PMID:17713547

NCBI chr 8:100,967,757...100,985,384
Ensembl chr 8:103,121,332...103,138,223

FES

FES proto-oncogene, tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr15:69,576,936...69,588,834
Ensembl chr15:88,774,965...88,786,965

IL34

interleukin 34

involved_in

GO_REF:0000107 GO_REF:0000118

Ensembl chr16:70,480,917...70,494,693

JUN

Jun proto-oncogene, AP-1 transcription factor subunit

murine WEHI-3B D+ cells with or without retinoic acid

RGD

PMID:7947389

RGD:2291846

NCBI chr 1:58,042,794...58,045,536

ZFP36L1

ZFP36 ring finger protein like 1

involved_in

GO_REF:0000107

NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805

positive regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD101

CD101 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:85,483,230...85,530,136
Ensembl chr 1:120,481,202...120,507,589

IL3

interleukin 3

acts_upstream_of_or_within

(PMID:1375116), (PMID:7690439)

PMID:1375116 PMID:7690439

NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213

KITLG

KIT ligand

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:86,036,501...86,124,274
Ensembl chr12:89,341,921...89,436,758

positive regulation of natural killer cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AXL

AXL receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr19:38,211,555...38,254,464
Ensembl chr19:46,719,615...46,761,747

FLT3LG

fms related receptor tyrosine kinase 3 ligand

acts_upstream_of_or_within

(PMID:14607906)

PMID:14607906

NCBI chr19:46,486,169...46,499,008

GAS6

growth arrest specific 6

involved_in

GO_REF:0000107

Ensembl chr13:113,968,843...114,009,562

IL15

interleukin 15

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:133,693,995...134,115,470
Ensembl chr 4:145,402,111...145,416,622

IL15RA

interleukin 15 receptor subunit alpha

acts_upstream_of_or_within

(PMID:14607906)

PMID:14607906

NCBI chr10:5,993,583...6,019,967

IL21

interleukin 21

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463

RASGRP1

RAS guanyl releasing protein 1

involved_in

GO_REF:0000107

NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315

TOX

thymocyte selection associated high mobility group box

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:55,246,933...55,553,839
Ensembl chr 8:56,922,773...57,219,410

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr14:45,085,146...45,114,965
Ensembl chr14:63,354,458...63,359,403

positive regulation of neutrophil differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EVI2B

ecotropic viral integration site 2B

involved_in

TreeGrafter

GO_REF:0000118

NCBI chr17:25,484,228...25,495,150
Ensembl chr17:26,229,023...26,230,368

IKZF1

IKAROS family zinc finger 1

acts_upstream_of_or_within

(PMID:12406904)

PMID:12406904

NCBI chr 7:50,946,817...51,047,168
Ensembl chr 7:51,191,685...51,291,245

positive regulation of NK T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AP3B1

adaptor related protein complex 3 subunit beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:37,015,518...37,305,769
Ensembl chr 5:37,503,162...37,840,205

AP3D1

adaptor related protein complex 3 subunit delta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:1,110,419...1,161,826
Ensembl chr19:2,085,540...2,137,593

CD1D

CD1d molecule

acts_upstream_of_or_within

(PMID:9133426)
(PMID:10201995)

PMID:9133426 PMID:10201995

NCBI chr 1:133,549,258...133,557,752
Ensembl chr 1:137,341,690...137,348,173

TGFBR2

transforming growth factor beta receptor 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856

ZBTB16

zinc finger and BTB domain containing 16

involved_in

GO_REF:0000107

NCBI chr11:108,938,414...109,133,819
Ensembl chr11:112,780,380...112,977,164

positive regulation of osteoclast development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GPR68

G protein-coupled receptor 68

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806

NINJ1

ninjurin 1

involved_in

(PMID:30700695)

PMID:30700695

NCBI chr 9:64,245,086...64,258,614
Ensembl chr 9:92,311,502...92,324,030

SLC9B2

solute carrier family 9 member B2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:95,474,854...95,532,311
Ensembl chr 4:106,100,229...106,155,749

TNFSF11

TNF superfamily member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr13:23,750,835...23,784,740

TYROBP

transmembrane immune signaling adaptor TYROBP

involved_in

GO_REF:0000107

NCBI chr19:32,821,279...32,825,488
Ensembl chr19:41,570,683...41,575,226

positive regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASXL2

ASXL transcriptional regulator 2

acts_upstream_of_or_within

(PMID:21490954)

PMID:21490954

NCBI chr2A:25,730,155...25,880,089
Ensembl chr2A:25,832,527...25,973,659

carbonic anhydrase 2

NCBI chr 8:81,991,037...82,009,010
Ensembl chr 8:83,597,440...83,632,580

CCL15

C-C motif chemokine ligand 15

NCBI chr17:20,793,702...20,809,383
Ensembl chr17:21,089,791...21,095,047

CCL5

C-C motif chemokine ligand 5

NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172

CCR1

C-C motif chemokine receptor 1

involved_in

GO_REF:0000107

NCBI chr 3:46,107,526...46,114,229
Ensembl chr 3:47,214,688...47,215,755

CREB1

cAMP responsive element binding protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130

CSF1

colony stimulating factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943

CSF1R

colony stimulating factor 1 receptor

NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415

EEIG1

estrogen-induced osteoclastogenesis regulator 1

involved_in

GO_REF:0000107

NCBI chr 9:99,061,030...99,101,144
Ensembl chr 9:127,731,243...127,771,098

FOS

Fos proto-oncogene, AP-1 transcription factor subunit

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766

GNAS

GNAS complex locus

acts_upstream_of_or_within

(PMID:15797856)

PMID:15797856

NCBI chr20:55,190,607...55,262,245

GSK3B

glycogen synthase kinase 3 beta

NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771

IFNG

interferon gamma

involved_in

GO_REF:0000107

NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829

IL12B

interleukin 12B

involved_in

GO_REF:0000107

NCBI chr 5:154,706,467...154,722,231
Ensembl chr 5:161,325,303...161,335,381

IL17A

interleukin 17A

involved_in

GO_REF:0000107

NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074

IL20

interleukin 20

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:182,468,571...182,472,440
Ensembl chr 1:186,747,086...186,750,952

IL23A

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617

KLF10

KLF transcription factor 10

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:99,302,943...99,310,099
Ensembl chr 8:101,462,915...101,469,982

LOC100978090

protein ALEX

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:55,204,188...55,206,608
Ensembl chr20:56,474,459...56,621,747

NEDD9

neural precursor cell expressed, developmentally down-regulated 9

involved_in

GO_REF:0000107

NCBI chr 6:11,022,321...11,071,747
Ensembl chr 6:11,297,701...11,420,186

NOTCH2

notch receptor 2

involved_in

(PMID:18710934)

PMID:18710934

NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840

OCSTAMP

osteoclast stimulatory transmembrane protein

involved_in

GO_REF:0000107

NCBI chr20:42,873,552...42,883,785
Ensembl chr20:43,958,736...43,968,110

POU4F1

POU class 4 homeobox 1

involved_in

(PMID:17668438)

PMID:17668438

NCBI chr13:59,821,614...59,829,671

POU4F2

POU class 4 homeobox 2

involved_in

GO_REF:0000107

NCBI chr 4:138,969,157...138,972,730
Ensembl chr 4:150,626,392...150,629,961

PPARGC1B

PPARG coactivator 1 beta

involved_in

GO_REF:0000107

NCBI chr 5:145,154,517...145,315,567
Ensembl chr 5:151,203,088...151,278,837

PPP3CA

protein phosphatase 3 catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394

RPTOR

regulatory associated protein of MTOR complex 1

involved_in

(PMID:27879318)

PMID:27879318

NCBI chr17:74,973,420...75,389,339
Ensembl chr17:80,705,544...81,118,708

TM4SF19

transmembrane 4 L six family member 19

involved_in

(PMID:38016540)

PMID:38016540

NCBI chr 3:193,670,511...193,674,645
Ensembl chr 3:203,608,788...203,616,808

TMEM64

transmembrane protein 64

involved_in
acts_upstream_of_or_within

GO_REF:0000107 GO_REF:0000118

NCBI chr 8:87,285,209...87,309,654
Ensembl chr 8:89,234,475...89,317,386

TNF

tumor necrosis factor

involved_in

GO_REF:0000107

NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381

TNFRSF11A

TNF receptor superfamily member 11a

involved_in

GO_REF:0000107

NCBI chr18:55,695,394...55,761,307
Ensembl chr18:59,034,770...59,075,044

TNFSF11

TNF superfamily member 11

acts_upstream_of_or_within
involved_in

ISO
IEA

RGD
Ensembl

PMID:11092398

GO_REF:0000107 RGD:730134

NCBI chr13:23,750,835...23,784,740

TRAF6

TNF receptor associated factor 6

involved_in

GO_REF:0000107

NCBI chr11:36,457,633...36,483,616
Ensembl chr11:36,335,609...36,356,334

TREM2

triggering receptor expressed on myeloid cells 2

involved_in

GO_REF:0000107

NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578

positive regulation of plasma cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DDRGK1

DDRGK domain containing 1

involved_in

GO_REF:0000107

NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789

IL10

interleukin 10

acts_upstream_of

GO_REF:0000107

NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371

IL2

interleukin 2

acts_upstream_of

GO_REF:0000107

NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984

XBP1

X-box binding protein 1

involved_in

GO_REF:0000107

NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943

positive regulation of pro-T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr14:45,085,146...45,114,965
Ensembl chr14:63,354,458...63,359,403

positive regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AMBRA1

autophagy and beclin 1 regulator 1

involved_in

GO_REF:0000107

NCBI chr11:46,355,026...46,556,091
Ensembl chr11:46,905,454...47,103,205

BCL6 transcription repressor

involved_in

GO_REF:0000107

NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124

CARMIL2

capping protein regulator and myosin 1 linker 2

acts_upstream_of_or_within

(PMID:23793062)

PMID:23793062

NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709

CD46

CD46 molecule

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046

CR1

complement C3b/C4b receptor 1 (Knops blood group)

involved_in

(PMID:25742728)

PMID:25742728

NCBI chr 1:183,094,601...183,246,957

DUSP10

dual specificity phosphatase 10

involved_in

GO_REF:0000107

NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720

FOXO3

forkhead box O3

involved_in

GO_REF:0000107

NCBI chr 6:106,360,519...106,485,676
Ensembl chr 6:110,406,266...110,516,272

forkhead box P3

involved_in
acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:41,550,462...41,567,492
Ensembl chr X:49,402,652...49,417,029

interleukin 2

NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984

IL4I1

interleukin 4 induced 1

involved_in

GO_REF:0000107

NCBI chr19:46,902,656...46,942,213
Ensembl chr19:55,819,080...55,858,389

KAT5

lysine acetyltransferase 5

involved_in

GO_REF:0000107

NCBI chr11:61,071,118...61,078,667
Ensembl chr11:64,404,572...64,412,667

leukocyte immunoglobulin like receptor B4

involved_in

(PMID:20935202), (PMID:22387553)

PMID:20935202 PMID:22387553

NCBI chr19:51,606,681...51,612,751

LOC100975566

butyrophilin subfamily 2 member A2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:26,215,215...26,227,261
Ensembl chr 6:26,873,828...26,885,592

galectin-9

involved_in

(PMID:25065622)

PMID:25065622

NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959

LOC100978774

patr class I histocompatibility antigen, alpha chain G

involved_in

GO_REF:0000107

NCBI chr 6:29,616,091...29,620,270
Ensembl chr 6:30,286,395...30,390,865

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:22387553)

PMID:22387553

NCBI chr16:10,196,432...10,198,205

SOX12

SRY-box transcription factor 12

involved_in

(PMID:30190287)

PMID:30190287

NCBI chr20:533,901...537,106

TGFB1

transforming growth factor beta 1

involved_in

GO_REF:0000107

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

VSIR

V-set immunoregulatory receptor

involved_in

GO_REF:0000107

NCBI chr10:68,218,230...68,243,687
Ensembl chr10:70,742,062...70,767,613

positive regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868

BAD

BCL2 associated agonist of cell death

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257

CD27

CD27 molecule

involved_in

InterPro

GO_REF:0000002

NCBI chr12:6,575,104...6,582,127
Ensembl chr12:6,492,119...6,499,427

CD74

CD74 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334

CYLD

CYLD lysine 63 deubiquitinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:31,004,393...31,064,546
Ensembl chr16:49,882,751...49,942,629

GATA3

GATA binding protein 3

involved_in

(PMID:20696860)

PMID:20696860

NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272

IL12A

interleukin 12A

acts_upstream_of_or_within

(PMID:22968459)

PMID:22968459

NCBI chr 3:157,011,675...157,019,897
Ensembl chr 3:165,061,505...165,068,666

IL1RL2

interleukin 1 receptor like 2

acts_upstream_of_or_within

GO_REF:0000107

Ensembl chr2A:103,237,996...103,289,414

interleukin 2

NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984

IL2RA

interleukin 2 receptor subunit alpha

NCBI chr10:6,053,549...6,103,863

IL4

interleukin 4

involved_in

GO_REF:0000107

NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581

IL7

interleukin 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:75,254,166...75,337,373
Ensembl chr 8:76,895,095...76,966,918

LOC100968989

HLA class II histocompatibility antigen, DM alpha chain

acts_upstream_of_or_within

(PMID:8598041), (PMID:9432982)
(PMID:8638109)
(PMID:8598040)

PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982

NCBI chr 6:32,518,060...32,537,989
Ensembl chr 6:33,634,123...33,637,988

LOC100971372

tyrosine-protein kinase ZAP-70

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2A:101,582,567...101,613,175
Ensembl chr2A:98,613,740...98,639,088

MDK

midkine

involved_in

GO_REF:0000107

NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254

PIK3R6

phosphoinositide-3-kinase regulatory subunit 6

involved_in

GO_REF:0000107

NCBI chr17:42,782,422...42,851,692
Ensembl chr17:47,518,629...47,585,160

PTPRC

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994

RAG1

recombination activating 1

involved_in

GO_REF:0000107

NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904

RHOH

ras homolog family member H

involved_in

GO_REF:0000107

NCBI chr 4:34,517,487...34,569,934
Ensembl chr 4:40,419,549...40,420,124

WNT10B

Wnt family member 10B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734

XBP1

X-box binding protein 1

involved_in

GO_REF:0000107

NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr14:45,085,146...45,114,965
Ensembl chr14:63,354,458...63,359,403

ZMIZ1

zinc finger MIZ-type containing 1

involved_in

GO_REF:0000107

NCBI chr10:75,581,794...75,829,748
Ensembl chr10:78,294,867...78,492,475

positive regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868

ADAM8

ADAM metallopeptidase domain 8

involved_in

GO_REF:0000107

Ensembl chr10:134,172,724...134,186,227

EGR3

early growth response 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:21,937,516...21,943,646
Ensembl chr 8:18,877,396...18,882,874

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:60,375,815...60,386,936
Ensembl chr X:70,433,360...70,437,590

IL7R

interleukin 7 receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:74,489,188...74,516,330
Ensembl chr 5:79,769,859...79,792,612

RASGRP1

RAS guanyl releasing protein 1

involved_in

GO_REF:0000107

NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

TESPA1

thymocyte expressed, positive selection associated 1

involved_in

(PMID:22561606)

PMID:22561606

NCBI chr12:33,765,283...33,800,883
Ensembl chr12:34,492,311...34,527,627

VNN1

vanin 1

involved_in

GO_REF:0000107

NCBI chr 6:130,459,268...130,491,167
Ensembl chr 6:134,566,117...134,598,784

positive regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA1

annexin A1

involved_in

GO_REF:0000107

NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779

CCL19

C-C motif chemokine ligand 19

involved_in

(PMID:15845453)

PMID:15845453

NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108

HLX

H2.0 like homeobox

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222

RIPK2

receptor interacting serine/threonine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268

SOCS5

suppressor of cytokine signaling 5

involved_in

(PMID:12242343)

PMID:12242343

NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041

positive regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MALT1

MALT1 paracaspase

involved_in

(PMID:25282160)

PMID:25282160

NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574

NFKBID

NFKB inhibitor delta

involved_in

(PMID:25282160)

PMID:25282160

NCBI chr19:32,805,772...32,817,778
Ensembl chr19:41,553,727...41,568,555

NFKBIZ

NFKB inhibitor zeta

involved_in

GO_REF:0000107

NCBI chr 3:98,914,957...98,948,467
Ensembl chr 3:105,616,645...105,628,300

NLRP3

NLR family pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216

positive regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BRD2

bromodomain containing 2

involved_in

GO_REF:0000107

NCBI chr 6:32,538,130...32,550,823
Ensembl chr 6:33,657,648...33,666,031

BRD4

bromodomain containing 4

involved_in

(PMID:28262505)

PMID:28262505

NCBI chr19:14,768,239...14,805,770
Ensembl chr19:15,754,930...15,789,600

EP300

E1A binding protein p300

involved_in

GO_REF:0000107

NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604

IL23A

interleukin 23 subunit alpha

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617

OPA1

OPA1 mitochondrial dynamin like GTPase

involved_in

GO_REF:0000107

NCBI chr 3:190,890,242...190,995,133
Ensembl chr 3:201,207,607...201,312,358

positive regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL18

interleukin 18

involved_in

GO_REF:0000107

NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371

IL4R

interleukin 4 receptor

acts_upstream_of_or_within

(PMID:16424184)

PMID:16424184

Ensembl chr16:27,642,702...27,737,445

IL6

interleukin 6

acts_upstream_of_or_within

(PMID:12594267)

PMID:12594267

NCBI chr 7:23,415,922...23,420,767

NLRP3

NLR family pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216

PRKCZ

protein kinase C zeta

involved_in

GO_REF:0000107

NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855

RARA

retinoic acid receptor alpha

involved_in

(PMID:18416830)

PMID:18416830

NCBI chr17:16,932,485...16,980,958

TNF superfamily member 4

involved_in

(PMID:18354165)

PMID:18354165

NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845

positive regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SHB

SH2 domain containing adaptor protein B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:37,768,566...37,921,897

regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANKLE1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr19:16,769,670...16,775,114
Ensembl chr19:17,744,570...17,750,070

regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANKLE1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr19:16,769,670...16,775,114
Ensembl chr19:17,744,570...17,750,070

CARD11

caspase recruitment domain family member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:3,166,788...3,304,729
Ensembl chr 7:3,258,736...3,332,999

CYLD

CYLD lysine 63 deubiquitinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:31,004,393...31,064,546
Ensembl chr16:49,882,751...49,942,629

FAS

Fas cell surface death receptor

acts_upstream_of_or_within

(PMID:6610701)

PMID:6610701

NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612

FCRL3

Fc receptor like 3

involved_in

GO_REF:0000107

NCBI chr 1:133,038,100...133,062,467
Ensembl chr 1:136,830,553...136,855,027

IKZF3

IKAROS family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr17:17,459,438...17,498,452
Ensembl chr17:17,643,750...17,741,479

LOC100982539

signal transducer CD24

acts_upstream_of_or_within

(PMID:7795661), (PMID:9028339)

PMID:7795661 PMID:9028339

NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847

LOC100986336

twinfilin-2

involved_in

GO_REF:0000107

NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743

NFAM1

NFAT activating protein with ITAM motif 1

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:15143214)

InterPro
MGI

PMID:15143214

GO_REF:0000002

NCBI chr22:23,276,675...23,332,932
Ensembl chr22:41,345,206...41,396,721

PTPN6

protein tyrosine phosphatase non-receptor type 6

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830

SLAMF8

SLAM family member 8

involved_in

(PMID:11313408)

PMID:11313408

NCBI chr 1:135,178,241...135,189,005

ZFP36L1

ZFP36 ring finger protein like 1

involved_in

GO_REF:0000107

NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805

ZFP36L2

ZFP36 ring finger protein like 2

involved_in

GO_REF:0000107

NCBI chr2A:43,311,744...43,315,928

regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SH3RF1

SH3 domain containing ring finger 1

involved_in

(PMID:27084103)

PMID:27084103

NCBI chr 4:161,319,093...161,495,917
Ensembl chr 4:173,394,739...173,567,096

regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KCNK18

potassium two pore domain channel subfamily K member 18

involved_in

GO_REF:0000107

NCBI chr10:113,775,944...113,792,520
Ensembl chr10:117,206,815...117,219,701

regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729

regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CEBPB

CCAAT enhancer binding protein beta

involved_in

(PMID:26526992)

PMID:26526992

NCBI chr20:46,533,163...46,535,282

LOC100982859

class I histocompatibility antigen, Gogo-B*0101 alpha chain

involved_in

GO_REF:0000107

NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067

regulation of extrathymic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PRDM1

PR/SET domain 1

involved_in

GO_REF:0000107

NCBI chr 6:103,899,410...103,923,389
Ensembl chr 6:107,773,229...107,796,815

zinc finger protein 683

involved_in

(PMID:27102484)

PMID:27102484

NCBI chr 1:25,622,548...25,636,106
Ensembl chr 1:26,690,359...26,703,755

regulation of gamma-delta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EGR3

early growth response 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 8:21,937,516...21,943,646
Ensembl chr 8:18,877,396...18,882,874

RORC

RAR related orphan receptor C

acts_upstream_of_or_within

(PMID:21737317)

PMID:21737317

NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490

SOX13

SRY-box transcription factor 13

acts_upstream_of_or_within

(PMID:21737317)

PMID:21737317

NCBI chr 1:179,675,017...179,730,628
Ensembl chr 1:184,003,907...184,016,504

TCF7

transcription factor 7

involved_in

(PMID:23562159)

PMID:23562159

NCBI chr 5:129,518,134...129,549,972
Ensembl chr 5:135,671,095...135,702,734

regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RARA

retinoic acid receptor alpha

acts_upstream_of_or_within

(PMID:11222375)

PMID:11222375

NCBI chr17:16,932,485...16,980,958

RBP1

retinol binding protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:136,554,315...136,576,682
Ensembl chr 3:144,153,937...144,176,209

regulation of lymphocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IKZF3

IKAROS family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr17:17,459,438...17,498,452
Ensembl chr17:17,643,750...17,741,479

NDFIP1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:137,467,161...137,511,569
Ensembl chr 5:143,600,789...143,622,913

RNF41

ring finger protein 41

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:32,693,349...32,710,866
Ensembl chr12:32,944,814...32,962,584

regulation of macrophage differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

QKI

QKI, KH domain containing RNA binding

involved_in

(PMID:27029405)

PMID:27029405

NCBI chr 6:161,361,413...161,523,414

regulation of mast cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TAL1

TAL bHLH transcription factor 1, erythroid differentiation factor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:46,524,484...46,540,595
Ensembl chr 1:48,042,594...48,048,622

regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BCL6 transcription repressor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124

regulation of monocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FOXP1

forkhead box P1

involved_in

GO_REF:0000107

NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173

regulation of myeloid leukocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NDFIP1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:137,467,161...137,511,569
Ensembl chr 5:143,600,789...143,622,913

regulation of natural killer cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

galectin-9

involved_in

(PMID:23408620)

PMID:23408620

NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959

PRDM1

PR/SET domain 1

involved_in

GO_REF:0000107

NCBI chr 6:103,899,410...103,923,389
Ensembl chr 6:107,773,229...107,796,815

zinc finger protein 683

involved_in

(PMID:27102484)

PMID:27102484

NCBI chr 1:25,622,548...25,636,106
Ensembl chr 1:26,690,359...26,703,755

regulation of natural killer cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

zinc finger protein 683

involved_in

(PMID:22885984)

PMID:22885984

NCBI chr 1:25,622,548...25,636,106
Ensembl chr 1:26,690,359...26,703,755

regulation of NK T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PRDM1

PR/SET domain 1

involved_in

GO_REF:0000107

NCBI chr 6:103,899,410...103,923,389
Ensembl chr 6:107,773,229...107,796,815

zinc finger protein 683

involved_in

(PMID:27102484)

PMID:27102484

NCBI chr 1:25,622,548...25,636,106
Ensembl chr 1:26,690,359...26,703,755

regulation of osteoclast differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APC

APC regulator of WNT signaling pathway

acts_upstream_of_or_within

(PMID:15802266)

PMID:15802266

NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709

CEBPB

CCAAT enhancer binding protein beta

involved_in

(PMID:19440205)

PMID:19440205

NCBI chr20:46,533,163...46,535,282

CTNNB1

catenin beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030

ESRRA

estrogen related receptor alpha

NCBI chr11:59,662,565...59,673,789
Ensembl chr11:63,009,295...63,018,744

FGFR3

fibroblast growth factor receptor 3

acts_upstream_of_or_within

(PMID:20053668)

PMID:20053668

NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692

FSHB

follicle stimulating hormone subunit beta

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:30,204,193...30,208,410
Ensembl chr11:30,095,486...30,100,167

FSHR

follicle stimulating hormone receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2A:49,088,450...49,287,688
Ensembl chr2A:50,008,328...50,207,258

MITF

melanocyte inducing transcription factor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:69,674,064...69,902,078
Ensembl chr 3:71,037,665...71,265,445

MTOR

mechanistic target of rapamycin kinase

involved_in

GO_REF:0000107

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

PRXL2A

peroxiredoxin like 2A

involved_in

GO_REF:0000107

NCBI chr10:76,808,869...76,837,447
Ensembl chr10:80,412,903...80,432,032

RASSF2

Ras association domain family member 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:4,804,802...4,845,633
Ensembl chr20:4,603,414...4,641,529

TFE3

transcription factor binding to IGHM enhancer 3

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:11930005)

InterPro
MGI

PMID:11930005

GO_REF:0000002

NCBI chr X:41,326,802...41,341,574
Ensembl chr X:49,182,795...49,197,194

TNF

tumor necrosis factor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381

TNFSF11

TNF superfamily member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr13:23,750,835...23,784,740

UBASH3B

ubiquitin associated and SH3 domain containing B

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr11:117,489,411...117,647,719
Ensembl chr11:121,410,545...121,563,133

ZBTB7A

zinc finger and BTB domain containing 7A

NCBI chr19:3,066,554...3,090,285

regulation of positive thymic T cell selection

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FOXN1

forkhead box N1

involved_in

GO_REF:0000107

NCBI chr17:28,237,150...28,272,010
Ensembl chr17:28,740,775...28,773,592

TOX

thymocyte selection associated high mobility group box

involved_in

GO_REF:0000107

NCBI chr 8:55,246,933...55,553,839
Ensembl chr 8:56,922,773...57,219,410

regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD28

CD28 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213

DICER1

dicer 1, ribonuclease III

acts_upstream_of_or_within

(PMID:18725527)

PMID:18725527

NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940

DROSHA

drosha ribonuclease III

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:78,813,923...78,945,149
Ensembl chr 5:84,194,546...84,322,310

FANCA

FA complementation group A

involved_in
acts_upstream_of_or_within

GO_REF:0000107 GO_REF:0000118

NCBI chr16:70,495,310...70,579,275
Ensembl chr16:90,163,950...90,245,147

FANCD2

FA complementation group D2

acts_upstream_of_or_within

(PMID:24501220)

PMID:24501220

NCBI chr 3:9,932,292...10,037,332
Ensembl chr 3:10,312,476...10,389,190

KAT2A

lysine acetyltransferase 2A

involved_in

GO_REF:0000107

NCBI chr17:15,194,414...15,202,818
Ensembl chr17:15,416,075...15,424,197

LCK

LCK proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923

PSG9

pregnancy specific beta-1-glycoprotein 9

acts_upstream_of_positive_effect

(PMID:27389696)

PMID:27389696

NCBI chr19:40,182,939...40,199,762

SH2B3

SH2B adaptor protein 3

NCBI chr12:108,977,344...109,024,029

TGFB1

transforming growth factor beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868

BRAF

B-Raf proto-oncogene, serine/threonine kinase

acts_upstream_of_or_within

(PMID:18228248)

PMID:18228248

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

CARD11

caspase recruitment domain family member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:3,166,788...3,304,729
Ensembl chr 7:3,258,736...3,332,999

CCR2

C-C motif chemokine receptor 2

involved_in

GO_REF:0000107

NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312

CRTAM

cytotoxic and regulatory T cell molecule

involved_in

GO_REF:0000107

NCBI chr11:117,671,581...117,705,818
Ensembl chr11:121,591,738...121,625,738

CYP26B1

cytochrome P450 family 26 subfamily B member 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2A:72,172,658...72,191,410
Ensembl chr2A:73,670,830...73,686,433

FAS

Fas cell surface death receptor

acts_upstream_of_or_within

(PMID:6610701)

PMID:6610701

NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612

IL15

interleukin 15

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:133,693,995...134,115,470
Ensembl chr 4:145,402,111...145,416,622

LOC100967723

HLA class II histocompatibility antigen, DO alpha chain

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:32,573,975...32,579,398
Ensembl chr 6:33,689,171...33,694,576

LOC100978670

PRELI domain-containing protein 1, mitochondrial-like

involved_in

GO_REF:0000107

NCBI chr2A:63,691,913...63,692,866

LOC100979921

PRELI domain-containing protein 1, mitochondrial-like

involved_in

GO_REF:0000107

NCBI chr 1:186,769,079...186,770,369

METTL3

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

involved_in

(PMID:28792938)

PMID:28792938

NCBI chr14:2,315,868...2,329,460
Ensembl chr14:20,392,665...20,405,906

PRELID1

PRELI domain containing 1

involved_in

GO_REF:0000107

NCBI chr 5:172,605,767...172,608,901
Ensembl chr 5:179,669,885...179,672,965

RAG1

recombination activating 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904

SLC46A2

solute carrier family 46 member 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:84,001,056...84,013,231
Ensembl chr 9:112,154,001...112,165,906

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660

regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868

ADRM1

ADRM1 26S proteasome ubiquitin receptor

involved_in

(PMID:21048919)

PMID:21048919

NCBI chr20:58,667,601...58,673,566
Ensembl chr20:59,985,358...59,991,668

ANKLE1

ankyrin repeat and LEM domain containing 1

NOT|involved_in

(PMID:27010503)

PMID:27010503

NCBI chr19:16,769,670...16,775,114
Ensembl chr19:17,744,570...17,750,070

CLPTM1

CLPTM1 regulator of GABA type A receptor forward trafficking

involved_in

GO_REF:0000107

NCBI chr19:41,901,649...41,940,476
Ensembl chr19:50,506,886...50,545,204

FOXN1

forkhead box N1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:28,237,150...28,272,010
Ensembl chr17:28,740,775...28,773,592

galectin-9

NOT|involved_in

(PMID:25065622)

PMID:25065622

NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959

SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr2A:39,019,046...39,162,248
Ensembl chr2A:39,773,760...39,911,961

SOS2

SOS Ras/Rho guanine nucleotide exchange factor 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr14:30,707,477...30,822,029
Ensembl chr14:49,014,782...49,101,764

ZEB1

zinc finger E-box binding homeobox 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:31,449,202...31,659,534
Ensembl chr10:32,046,491...32,253,550

regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL27

interleukin 27

involved_in

(PMID:12734330)

PMID:12734330

regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCL20

C-C motif chemokine ligand 20

NOT|involved_in

(PMID:19050256)

PMID:19050256

NCBI chr2B:115,052,768...115,056,479
Ensembl chr2B:233,862,505...233,866,225

CCR6

C-C motif chemokine receptor 6

NOT|involved_in

(PMID:19050256)

PMID:19050256

NCBI chr 6:165,094,563...165,109,774
Ensembl chr 6:170,069,689...170,084,779

regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GATA3

GATA binding protein 3

acts_upstream_of_or_within

(PMID:18776904)

PMID:18776904

NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272

LOC100987081

HLA class II histocompatibility antigen, DR alpha chain

involved_in

GO_REF:0000107

NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within