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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of proteasomal protein catabolic process
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Accession:GO:1901799 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.
Synonyms:exact_synonym: down regulation of proteasome-mediated protein catabolic process;   down regulation of proteasome-mediated protein catabolism;   down-regulation of proteasomal protein catabolic process;   downregulation of proteasomal protein catabolic process;   downregulation of proteasome-mediated protein catabolic process;   downregulation of proteasome-mediated protein catabolism;   inhibition of proteasome-mediated protein catabolic process;   inhibition of proteasome-mediated protein catabolism;   negative regulation of proteasome-mediated protein catabolic process;   negative regulation of proteasome-mediated protein catabolism
 narrow_synonym: inhibition of proteasomal protein catabolic process


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negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in ISO
IEA		 (PMID:8175643)
GO_REF:0000107		 RGD
Ensembl		 PMID:8175643 GO_REF:0000107 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G F8a1 coagulation factor VIII-associated 1 involved_in ISO
ISS		 (PMID:27815841)
GO_REF:0000024		 RGD
UniProt		 PMID:27815841 GO_REF:0000024 NCBI chr  X:150,957,357...150,958,871
Ensembl chr  X:150,916,679...150,960,168 		JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 involved_in ISO (PMID:21669198) RGD PMID:21669198 NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in IMP
IEA
ISO		 PMID:17517623
GO_REF:0000107
(PMID:17517623)		 Ensembl
RGD		 PMID:17517623 PMID:17517623 GO_REF:0000107, RGD:13514081 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 involved_in ISO (PMID:25681212) RGD PMID:25681212 NCBI chr11:94,657,817...94,726,451
Ensembl chr11:81,193,649...81,221,784 		JBrowse link
G LOC134484027 40-kDa huntingtin-associated protein involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29295817)		 UniProt
RGD		 PMID:29295817 GO_REF:0000024 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Ophn1 oligophrenin 1 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:21874017)		 GO_Central
Ensembl
RGD		 PMID:21874017 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633 		JBrowse link
G Prkcg protein kinase C, gamma involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:23185022)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23185022 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Psme3ip1 proteasome activator subunit 3 interacting protein 1 involved_in ISO (PMID:29934401) RGD PMID:29934401 NCBI chr19:10,401,400...10,430,059
Ensembl chr19:10,401,532...10,429,987 		JBrowse link
G Psmf1 proteasome inhibitor subunit 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:10764772)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:10764772 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546 		JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO MGI:2176228|MGI:5758867 (PMID:25683716) RGD PMID:25683716 NCBI chr10:51,744,656...51,757,246
Ensembl chr10:51,744,656...51,757,237 		JBrowse link
G Usp19 ubiquitin specific peptidase 19 involved_in ISO (PMID:25088257) RGD PMID:25088257 NCBI chr 8:118,069,227...118,080,283
Ensembl chr 8:109,190,724...109,201,741 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18606867)		 UniProt
RGD		 PMID:18606867 GO_REF:0000024 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:23129660)		 UniProt
RGD		 PMID:23129660 GO_REF:0000024 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Svip small VCP interacting protein involved_in IDA
ISO
IBA		 PMID:17000876
(PMID:17872946)
GO_REF:0000033		 RGD
GO_Central		 PMID:17872946 PMID:17000876 GO_REF:0000033, RGD:10047192 NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116 		JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
G Ubxn2a UBX domain protein 2A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26265139)		 UniProt
RGD		 PMID:26265139 GO_REF:0000024 NCBI chr 6:27,884,364...27,912,767
Ensembl chr 6:27,884,680...27,912,649
Ensembl chr20:27,884,680...27,912,649 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO
IBA		 (PMID:19135427)
GO_REF:0000033		 RGD
GO_Central		 PMID:19135427 GO_REF:0000033 NCBI chr18:1,292,745...1,330,867
Ensembl chr18:1,019,400...1,057,519 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO
IEA		 (PMID:22590560)
GO_REF:0000107		 RGD
Ensembl		 PMID:22590560 GO_REF:0000107 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18678708)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18678708 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Camlg calcium modulating ligand involved_in ISO UniProtKB:Q9H9V4 (PMID:20553626) RGD PMID:20553626 NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO
IEA		 (PMID:23398316)
GO_REF:0000107		 RGD
Ensembl		 PMID:23398316 GO_REF:0000107 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISO UniProtKB:P19784|UniProtKB:P25686|UniProtKB:P67870 (PMID:28031292) RGD PMID:28031292 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO
IEA		 UniProtKB:P25686|UniProtKB:P67870|UniProtKB:P68400 (PMID:28031292)
GO_REF:0000107		 RGD
Ensembl		 PMID:28031292 GO_REF:0000107 NCBI chr19:9,562,340...9,602,136
Ensembl chr19:9,556,260...9,596,080 		JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO (PMID:28031292) RGD PMID:28031292 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO
IEA		 (PMID:28263186)
GO_REF:0000107		 RGD
Ensembl		 PMID:28263186 GO_REF:0000107 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H involved_in ISO
IEA		 (PMID:32269044)
GO_REF:0000107		 RGD
Ensembl		 PMID:32269044 GO_REF:0000107 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G ENSRNOG00000069696 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:11,225,135...11,226,004 JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in ISO
IBA
IEA
ISS		 (PMID:15313915)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:15313915 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11546783)		 Ensembl
RGD		 PMID:11546783 GO_REF:0000107 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24904118)
GO:0010628 (PMID:24904118)		 RGD PMID:24904118 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24613385)		 UniProt
Ensembl
RGD		 PMID:24613385 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:24960163)		 GO_Central
RGD		 PMID:24960163 GO_REF:0000033 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Map1a microtubule-associated protein 1A involved_in ISO (PMID:26609151) RGD PMID:26609151 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of_or_within ISO MGI:2450997 (PMID:23695157) RGD PMID:23695157 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860 		JBrowse link
G N4bp1 Nedd4 binding protein 1 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:17592138)		 GO_Central
Ensembl
RGD		 PMID:17592138 GO_REF:0000033 GO_REF:0000107 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO
IEA		 (PMID:22522597)
GO_REF:0000107		 RGD
Ensembl		 PMID:22522597 GO_REF:0000107 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO		 GO_REF:0000107
(PMID:26678539)		 Ensembl
RGD		 PMID:26678539 GO_REF:0000107 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:17015834) RGD PMID:17015834 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (PMID:21715333) RGD PMID:21715333 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Phf20l1 PHD finger protein 20-like 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24492612)		 UniProt
Ensembl
RGD		 PMID:24492612 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526 		JBrowse link
G Rgs19 regulator of G-protein signaling 19 involved_in ISO (PMID:11546783) RGD PMID:11546783 NCBI chr 3:168,804,532...168,813,035
Ensembl chr 3:168,804,874...168,810,097 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21804542)		 UniProt
Ensembl
RGD		 PMID:21804542 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Rybp RING1 and YY1 binding protein involved_in ISO (PMID:27060496) RGD PMID:27060496 NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316 		JBrowse link
G Senp1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO
IEA		 MGI:3818522 (PMID:17981124)
GO_REF:0000107		 RGD
Ensembl		 PMID:17981124 GO_REF:0000107 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA		 (PMID:16611981)
GO_REF:0000107		 RGD
Ensembl		 PMID:16611981 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 acts_upstream_of_or_within ISO
IEA		 (PMID:22285184)
GO_REF:0000107		 RGD
Ensembl		 PMID:22285184 GO_REF:0000107 NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:11278372) RGD PMID:11278372 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Tlk2 tousled-like kinase 2 involved_in ISO (PMID:20016786) RGD PMID:20016786 NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561 		JBrowse link
G Tmem25 transmembrane protein 25 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:54,003,907...54,009,469
Ensembl chr 8:45,107,121...45,116,389 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
IBA
ISS		 (PMID:23213251)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:23213251 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO
IEA		 MGI:5588394 (PMID:31537781)
GO_REF:0000107		 RGD
Ensembl		 PMID:31537781 GO_REF:0000107 NCBI chr 8:54,009,522...54,013,129 JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:20351172)		 UniProt
GO_Central
RGD		 PMID:20351172 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:23770237) RGD PMID:23770237 NCBI chr13:58,070,947...58,106,825
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Usp26 ubiquitin specific peptidase 26 involved_in ISO (PMID:28839133) RGD PMID:28839133 NCBI chr  X:131,317,200...131,363,964
Ensembl chr  X:131,319,194...131,363,970 		JBrowse link
G Usp38 ubiquitin specific peptidase 38 involved_in ISO
IEA		 (PMID:34102342)
GO_REF:0000107		 RGD
Ensembl		 PMID:34102342 GO_REF:0000107 NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:37534934) RGD PMID:37534934 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISO
IEA		 (PMID:26678539)
GO_REF:0000107		 RGD
Ensembl		 PMID:26678539 GO_REF:0000107 NCBI chr10:7,335,508...7,432,018
Ensembl chr10:6,828,795...6,925,355 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO
IEA		 (PMID:33378666)
GO_REF:0000107		 RGD
Ensembl		 PMID:33378666 GO_REF:0000107 NCBI chr  X:12,261,633...12,399,780
Ensembl chr  X:9,588,825...9,696,711 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pabpn1l PABPN1 like acts_upstream_of_or_within ISO
IEA		 (PMID:32558204)
GO_REF:0000107		 RGD
Ensembl		 PMID:32558204 GO_REF:0000107 NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366 		JBrowse link
G Styx serine/threonine/tyrosine interacting protein involved_in ISO
IBA		 (PMID:28007894)
GO_REF:0000033		 RGD
GO_Central		 PMID:28007894 GO_REF:0000033 NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    negative regulation of biological process 5837
      negative regulation of cellular process 5609
        negative regulation of metabolic process 3146
          negative regulation of catabolic process 380
            negative regulation of protein catabolic process 125
              negative regulation of proteasomal protein catabolic process 64
                negative regulation of ERAD pathway 7
                negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 46
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        regulation of cellular process 13030
          regulation of metabolic process 6786
            regulation of macromolecule metabolic process 6240
              regulation of protein metabolic process 1968
                regulation of proteolysis 440
                  regulation of proteolysis involved in protein catabolic process 241
                    regulation of proteasomal protein catabolic process 202
                      negative regulation of proteasomal protein catabolic process 64
                        negative regulation of ERAD pathway 7
                        negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 46
paths to the root