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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-amino acid biosynthetic process
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Accession:GO:1901607 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an alpha-amino acid.
Synonyms:exact_synonym: alpha-amino acid anabolism;   alpha-amino acid biosynthesis;   alpha-amino acid formation;   alpha-amino acid synthesis


show annotations for term's descendants           Sort by:
'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA		 (PMID:10529246)
GO_REF:0000107		 RGD
Ensembl		 PMID:10529246 GO_REF:0000107 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
arginine biosynthetic process via ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr12:32,295,779...32,313,257
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Otc ornithine transcarbamylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO		 GO_REF:0000033
(PMID:2573597)		 GO_Central
RGD		 PMID:2573597 PMID:2887559 GO_REF:0000033, RGD:2316002 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:48,126,808...48,139,073
Ensembl chr 9:48,126,808...48,139,073 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:4193185)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:4193185 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) RGD PMID:4193185 NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IDA RGD PMID:7053379 RGD:10755426 NCBI chr 6:31,012,091...31,035,098
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Otc ornithine transcarbamylase involved_in IDA
IBA
ISO		 GO_REF:0000033
(PMID:2556444), (PMID:8112735)		 GO_Central
RGD		 PMID:2556444 PMID:8112735 PMID:9472964 GO_REF:0000033, RGD:4144071 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in
acts_upstream_of_or_within		 ISO (PMID:24416422)
MGI:1857139 (PMID:15030387)		 RGD PMID:15030387 PMID:24416422 NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cth cystathionine gamma-lyase involved_in IEA
ISS
ISO		 GO_REF:0000041
GO_REF:0000024
(PMID:10212249)		 UniProt
RGD		 PMID:10212249 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12468440)		 Ensembl
RGD		 PMID:12468440 GO_REF:0000107 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in IEA GO_REF:0000002
GO_REF:0000104		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cth cystathionine gamma-lyase involved_in ISO
IBA
IEA		 (PMID:19428278)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:19428278 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
D-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srr serine racemase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11054547), (PMID:15193426)
(PMID:10557334), (PMID:11054547), (PMID:12021263), (PMID:15710237)
GO_REF:0000033		 RGD
GO_Central		 PMID:10557334 PMID:11054547 PMID:12021263 PMID:15193426 PMID:15710237 GO_REF:0000033 NCBI chr10:60,267,936...60,285,094
Ensembl chr10:59,769,571...59,787,011 		JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase involved_in IEA
ISO
IBA
ISS		 GO_REF:0000107
(PMID:22228304)
GO_REF:0000033
GO_REF:0000024
(PMID:16899818), (PMID:22049910)		 Ensembl
RGD
GO_Central
UniProt		 PMID:16899818 PMID:22049910 PMID:22228304 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gls2 glutaminase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:617,288...633,426 		JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:76,504,868...76,599,536
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
glutamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glul glutamate-ammonia ligase involved_in IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro
RGD		 PMID:4403443 PMID:28323 GO_REF:0000002 GO_REF:0000033, RGD:2301548, RGD:2301547 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain involved_in
NOT|involved_in		 IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907 		JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hao1 hydroxyacid oxidase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721 		JBrowse link
G Sardh sarcosine dehydrogenase IDA RGD PMID:2417560 RGD:597830057 NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:10,510,553...10,573,874 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Tha1 threonine aldolase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:103,094,681...103,100,169
Ensembl chr10:103,094,681...103,100,519 		JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000065410 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:178,497,468...178,499,169 JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IDA
IBA		 in the presence of tetrahydrofolate
GO_REF:0000033		 GO_Central
RGD		 PMID:3110140 GO_REF:0000033, RGD:2300383 NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IDA
IBA		 in the presence of tetrahydrofolate
GO_REF:0000033		 GO_Central
RGD		 PMID:3110140 GO_REF:0000033, RGD:2300383 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate aminotransferase involved_in IDA
ISO
IBA		 (PMID:22198249)
GO_REF:0000033		 RGD
GO_Central		 PMID:22198249 PMID:12383475 GO_REF:0000033, RGD:1599457 NCBI chr 9:101,122,793...101,132,746
Ensembl chr 9:93,675,384...93,685,336 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 involved_in ISO (PMID:20018850) RGD PMID:20018850 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA		 (PMID:10934207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10934207 GO_REF:0000107 NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16447251)		 Ensembl
RGD		 PMID:16447251 GO_REF:0000107 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
isoleucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilvbl ilvB acetolactate synthase like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924 		JBrowse link
L-arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase involved_in NAS
IEA
ISO
ISS		 GO_REF:0000041
(PMID:22081021)
(PMID:11747432), (PMID:11747433)
GO_REF:0000024		 UniProt
RGD		 PMID:11747432 PMID:11747433 PMID:22081021 PMID:2789519 GO_REF:0000024 GO_REF:0000041, RGD:632221 NCBI chr12:32,295,779...32,313,257
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in IDA
IBA
IMP
ISO
IEA		 GO_REF:0000033
PMID:19491403
(PMID:18473344), (PMID:27287393), (PMID:8792870)
GO_REF:0000041		 GO_Central
RGD
UniProt		 PMID:8792870 PMID:18473344 PMID:27287393 PMID:12470967 PMID:19491403 GO_REF:0000033 GO_REF:0000041, RGD:631755, RGD:12859071 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Nags N-acetylglutamate synthase involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr10:87,598,516...87,602,650
Ensembl chr10:87,098,330...87,102,465 		JBrowse link
G Otc ornithine transcarbamylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
L-glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 IDA RGD PMID:16489927 RGD:13504861 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 IDA RGD PMID:16489927 RGD:13504861 NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
L-histidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1-ps1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, pseudogene 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:116,195,791...116,198,973 JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
L-leucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11733007 GO_REF:0000033, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
IBA		 (PMID:18230605)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in ISO
IBA
IEA		 (PMID:18230605)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in ISO
IEA
ISS		 (PMID:15938715)
GO_REF:0000041
GO_REF:0000024		 RGD
UniProt		 PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842 		JBrowse link
G Apip APAF1 interacting protein involved_in ISO
IEA
IBA		 (PMID:22837397), (PMID:23285211)
GO_REF:0000041
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:22837397 PMID:23285211 GO_REF:0000033 GO_REF:0000041 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in ISO
IEA
IBA
ISS		 (PMID:15843022)
GO_REF:0000041
GO_REF:0000033
GO_REF:0000024		 RGD
UniProt
GO_Central		 PMID:15843022 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000041		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000041 NCBI chr 5:108,990,270...109,036,494
Ensembl chr 5:103,873,020...103,939,406 		JBrowse link
L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799 		JBrowse link
G Noxred1 NADP-dependent oxidoreductase domain containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:106,862,350...106,888,113
Ensembl chr 6:106,862,343...106,884,712 		JBrowse link
G Oat ornithine aminotransferase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in IEA
ISO
IBA		 GO_REF:0000041
(PMID:23024808), (PMID:28258219)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:23024808 PMID:28258219 GO_REF:0000033 GO_REF:0000041 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr13:95,158,236...95,162,030
Ensembl chr13:92,626,471...92,634,184 		JBrowse link
G Pycr3 pyrroline-5-carboxylate reductase 3 involved_in IEA
ISO
IBA
ISS		 GO_REF:0000041
(PMID:23024808), (PMID:36414121)
GO_REF:0000033
GO_REF:0000024		 UniProt
RGD
GO_Central		 PMID:23024808 PMID:36414121 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr 7:107,603,543...107,608,831
Ensembl chr 7:107,581,930...107,608,799 		JBrowse link
L-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07011698.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:153,941,154...153,942,719 JBrowse link
G Phgdh phosphoglycerate dehydrogenase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 involved_in ISO
IBA		 (PMID:37627284)
GO_REF:0000033		 RGD
GO_Central		 PMID:37627284 GO_REF:0000033 NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Psph phosphoserine phosphatase involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:14673469)		 UniProt
GO_Central
RGD		 PMID:14673469 GO_REF:0000024 GO_REF:0000033 NCBI chr12:32,527,091...32,541,182
Ensembl chr12:26,883,133...26,905,074 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA RGD PMID:10457370 RGD:2300380 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
L-valine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007 		JBrowse link
G Ilvbl ilvB acetolactate synthase like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924 		JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966 		JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase acts_upstream_of_or_within IDA
ISO		 (PMID:15217352) RGD PMID:15217352 PMID:15845641 RGD:1359026 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA		 (PMID:25633902)
GO_REF:0000107		 RGD
Ensembl		 PMID:25633902 GO_REF:0000107 NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2385823 (PMID:15217352)
GO_REF:0000033		 RGD
GO_Central		 PMID:15217352 GO_REF:0000033 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO		 GO_REF:0000033
PMID:20424322
MGI:2180496 (PMID:11158293)
(PMID:23825108)		 GO_Central
RGD		 PMID:11158293 PMID:23825108 PMID:15845641 PMID:20424322 PMID:11730351 GO_REF:0000033, RGD:1359026, RGD:10054082, RGD:1601423 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
IEA		 (PMID:11466310)
GO_REF:0000033
GO_REF:0000043
(PMID:17369066)		 RGD
GO_Central
UniProt		 PMID:11466310 PMID:17369066 GO_REF:0000033 GO_REF:0000043 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:47,708,157...47,807,389
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
ornithine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase acts_upstream_of ISS
ISO		 GO_REF:0000024
(PMID:16731528)		 ParkinsonsUK-UCL
RGD		 PMID:16731528 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:16730026) RGD PMID:16730026 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23024808)		 UniProt
RGD		 PMID:23024808 GO_REF:0000024 NCBI chr13:95,158,236...95,162,030
Ensembl chr13:92,626,471...92,634,184 		JBrowse link
regulation of arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:19284480) RGD PMID:19284480 NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
selenocysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sephs1 selenophosphate synthetase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:73,354,435...73,382,803
Ensembl chr17:73,356,530...73,382,593 		JBrowse link
G Sephs2 selenophosphate synthetase 2 acts_upstream_of_or_within ISO (PMID:17346238) RGD PMID:17346238 NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497 		JBrowse link
serine family amino acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA		 (PMID:25633902)
GO_REF:0000107		 RGD
Ensembl		 PMID:25633902 GO_REF:0000107 NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT|acts_upstream_of_or_within ISO (PMID:17034760) RGD PMID:17034760 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017 		JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16953590 GO_REF:0000033, RGD:1601531 NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IEA		 GO_REF:0000108 GOC
RGD		 PMID:10839989 GO_REF:0000108, RGD:1601535 NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,845,161...8,896,343
Ensembl chr17:8,845,084...8,910,539 		JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,898,074...8,910,538
Ensembl chr17:8,845,084...8,910,539
Ensembl chr 7:8,845,084...8,910,539 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        biosynthetic process 8663
          amino acid biosynthetic process 78
            alpha-amino acid biosynthetic process 69
              1-aminocyclopropane-1-carboxylate biosynthetic process 0
              4-hydroxyproline biosynthetic process 0
              D-amino acid biosynthetic process + 1
              L-amino acid biosynthetic process + 54
              alanine biosynthetic process + 0
              arginine biosynthetic process via ornithine + 2
              citrulline biosynthetic process + 4
              homocysteine biosynthetic process + 0
              isoleucine biosynthetic process + 1
              ornithine biosynthetic process 1
              sarcosine biosynthetic process 0
              serine family amino acid biosynthetic process + 18
Path 2
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        small molecule metabolic process 1918
          organic acid metabolic process 1043
            oxoacid metabolic process 1022
              carboxylic acid metabolic process 1007
                carboxylic acid biosynthetic process 345
                  alpha-amino acid biosynthetic process 69
                    1-aminocyclopropane-1-carboxylate biosynthetic process 0
                    4-hydroxyproline biosynthetic process 0
                    D-amino acid biosynthetic process + 1
                    L-amino acid biosynthetic process + 54
                    alanine biosynthetic process + 0
                    arginine biosynthetic process via ornithine + 2
                    citrulline biosynthetic process + 4
                    homocysteine biosynthetic process + 0
                    isoleucine biosynthetic process + 1
                    ornithine biosynthetic process 1
                    sarcosine biosynthetic process 0
                    serine family amino acid biosynthetic process + 18
paths to the root