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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of neuroinflammatory response
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Accession:GO:0150077 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of neuroinflammatory response.
Synonyms:only_in_taxon: NCBITaxon:7742 ! Vertebrata



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regulation of neuroinflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd200 Cd200 molecule involved_in IGI PMID:10981966 ARUK-UCL PMID:10981966 RGD:61663 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Cd200r1 CD200 receptor 1 involved_in IGI
IEA
PMID:10981966
GO_REF:0000002
InterPro PMID:10981966 GO_REF:0000002, RGD:61663 NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285
JBrowse link
G Cd200r1l CD200 receptor 1-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:55,842,632...55,860,914
Ensembl chr11:55,842,634...55,885,680
JBrowse link
G Dagla diacylglycerol lipase, alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26779719)
UniProt
Ensembl
RGD
PMID:26779719 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:29662056)
UniProt
RGD
PMID:29662056 GO_REF:0000024 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
ISO
IMP
GO_REF:0000024
(PMID:29662056)
PMID:28284343
UniProt
RGD
PMID:29662056 PMID:28284343 GO_REF:0000024, RGD:14397556 NCBI chr10:102,257,413...102,263,086
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (PMID:28052249) RGD PMID:28052249 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
negative regulation of astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P05067|UniProtKB:P49768 (PMID:20005821)
Ensembl
RGD
PMID:20005821 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:30792350)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:30792350 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29407460) RGD PMID:29407460 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
negative regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst7 cystatin F involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:5910746 (PMID:28251676)
GO_Central
RGD
PMID:28251676 GO_REF:0000033 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IDA PMID:19627440 ARUK-UCL PMID:19627440 RGD:13673772 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Grn granulin precursor involved_in ISS
ISO
GO_REF:0000024
(PMID:23041626)
UniProt
RGD
PMID:23041626 GO_REF:0000024 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P05067|UniProtKB:P49768 (PMID:20005821)
Ensembl
RGD
PMID:20005821 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:30792350)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30792350 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO RNAcentral:URS000024A59E_10090 (PMID:30412727) RGD PMID:30412727 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Syt11 synaptotagmin 11 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28686317)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28686317 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Tafa3 TAFA chemokine like family member 3 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:25595455)
GO_Central
RGD
PMID:25595455 GO_REF:0000033 NCBI chr 2:192,264,153...192,280,356
Ensembl chr 2:192,267,093...192,274,019
JBrowse link
negative regulation of neuroinflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd200 Cd200 molecule involved_in IGI
ISO
IBA
PMID:18164423
(PMID:11099416)
GO_REF:0000033
RGD
GO_Central
PMID:11099416 PMID:18164423 GO_REF:0000033, RGD:13792521 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Cd200l1 CD200 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:55,350,433...55,401,528
Ensembl chr11:55,336,109...55,401,373
JBrowse link
G Cd200l2 CD200 molecule like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:55,279,853...55,326,753
Ensembl chr11:55,280,418...55,303,827
JBrowse link
G Cd200r1 CD200 receptor 1 involved_in IGI PMID:18164423 ARUK-UCL PMID:18164423 RGD:13792521 NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285
JBrowse link
G Ifnb1 interferon beta 1 IDA RGD PMID:12973019 RGD:401851924 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
RNAcentral:URS000034B6F5_9606 (PMID:27277332)
GO_REF:0000107
RGD
Ensembl
PMID:27277332 GO_REF:0000107 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:30792350)
UniProt
Ensembl
RGD
PMID:30792350 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO RNAcentral:URS000024A59E_10090 (PMID:30412727) RGD PMID:30412727 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Sbno1 strawberry notch homolog 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:39343943)
UniProt
RGD
PMID:39343943 GO_REF:0000024 NCBI chr12:32,175,176...32,234,200
Ensembl chr12:32,185,485...32,230,158
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO
GO_REF:0000033
(PMID:27147664)
GO_Central
RGD
PMID:27147664 GO_REF:0000033 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IEA
(PMID:32514138)
GO_REF:0000107
(PMID:29407460), (PMID:31134514), (PMID:31900229)
RGD
Ensembl
PMID:29407460 PMID:31134514 PMID:31900229 PMID:32514138 GO_REF:0000107 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
positive regulation of astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33841088 RGD:151665762 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
positive regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO
IEA
(PMID:28251676)
GO_REF:0000107
RGD
Ensembl
PMID:28251676 GO_REF:0000107 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IMP RGD PMID:21750563 RGD:329955444 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:22302802 RGD:13462052 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mmp8 matrix metallopeptidase 8 acts_upstream_of ISO
IEA
(PMID:25049354)
GO_REF:0000107
RGD
Ensembl
PMID:25049354 GO_REF:0000107 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:19100238) RGD PMID:19100238 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245
JBrowse link
G Tafa3 TAFA chemokine like family member 3 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:25595455)
GO_Central
RGD
PMID:25595455 GO_REF:0000033 NCBI chr 2:192,264,153...192,280,356
Ensembl chr 2:192,267,093...192,274,019
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IBA
IEA
(PMID:24990881)
GO_REF:0000033
(PMID:24990881), (PMID:25631124), (PMID:29752066), (PMID:30617257), (PMID:31370707)
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:24990881 PMID:25631124 PMID:29752066 PMID:30617257 PMID:31370707 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO
IEA
(PMID:19118186)
GO_REF:0000107
RGD
Ensembl
PMID:19118186 GO_REF:0000107 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774
JBrowse link
positive regulation of neuroinflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir206 microRNA 206 involved_in ISO (PMID:27277332) RGD PMID:27277332 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IMP
IEA
ISO
PMID:25049354
GO_REF:0000107
(PMID:25049354)
Ensembl
RGD
PMID:25049354 PMID:25049354 GO_REF:0000107, RGD:13792525 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16374777)
UniProt
Ensembl
RGD
PMID:16374777 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO (PMID:32514138) RGD PMID:32514138 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:25631124) RGD PMID:25631124 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase IMP RGD PMID:28007901 RGD:12879399 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:34433553)
UniProt
RGD
PMID:34433553 GO_REF:0000024 NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IMP rat gene in mouse model RGD PMID:17473852 RGD:5688754 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:29662056)
UniProt
RGD
PMID:29662056 GO_REF:0000024 NCBI chr10:102,257,413...102,263,086
Ensembl chr10:101,758,711...101,764,240
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    response to stimulus 11082
      regulation of response to stimulus 4358
        regulation of response to external stimulus 1200
          regulation of inflammatory response 438
            regulation of neuroinflammatory response 34
              negative regulation of neuroinflammatory response + 17
              positive regulation of neuroinflammatory response + 12
              regulation of microglial cell activation + 19
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        regulation of response to stimulus 4358
          regulation of response to stress 1484
            regulation of defense response 910
              regulation of inflammatory response 438
                regulation of neuroinflammatory response 34
                  negative regulation of neuroinflammatory response + 17
                  positive regulation of neuroinflammatory response + 12
                  regulation of microglial cell activation + 19
paths to the root