ONTOLOGY REPORT - ANNOTATIONS
Term: pore-forming activity
Accession: GO:0140911
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Definition: An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death.
Synonyms: narrow_synonym: canonical holin activity; holin activity; pinholin activity
alt_id: GO:0034290; GO:0034291; GO:0034292
xref: TC:1.C
G
Mmd
monocyte to macrophage differentiation-associated
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528
G
Mmd2
monocyte to macrophage differentiation-associated 2
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773
G
Mpeg1
macrophage expressed 1
enables
ISO
(PMID:26402460)
RGD
PMID:26402460
NCBI chr 1:209,452,176...209,456,692
Ensembl chr 1:209,452,133...209,458,855
G
Prf1
perforin 1
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
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