defense response to symbiont - Ontology Report

Janus kinase 2

involved_in

ISO
IEA

(PMID:12426001)
GO_REF:0000107

RGD
Ensembl
InterPro
GO_Central

PMID:12426001

GO_REF:0000107

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

activation of innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aim2

absent in melanoma 2

involved_in

ISO
IEA
IBA

(PMID:19158675), (PMID:19158676), (PMID:19158679)
GO_REF:0000107
GO_REF:0000002
(PMID:19158676)
GO_REF:0000033

PMID:19158675 PMID:19158676 PMID:19158679

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975

Casp6

caspase 6

involved_in

ISO
IEA
ISS

(PMID:32298652)
GO_REF:0000107
GO_REF:0000024

PMID:32298652

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

cyclic GMP-AMP synthase

involved_in

ISO
IEA
IBA

(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:29426904), (PMID:30007416), (PMID:32817552), (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35438208)
GO_REF:0000107
(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:29426904), (PMID:32911480), (PMID:32911481), (PMID:32913000)
GO_REF:0000033

PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More...

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496

ENSRNOG00000069878

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033

Ensembl chr13:85,977,035...85,994,718

Gbp1

guanylate binding protein 1

involved_in

ISO

(PMID:24739961)

NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131

guanylate binding protein 2

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:24739961)
GO_REF:0000024

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571

Gbp4

guanylate binding protein 4

involved_in

ISO
IEA

(PMID:24739961)
GO_REF:0000107

GO_REF:0000107

NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879

guanylate binding protein 5

involved_in

ISO
IEA

(PMID:24739961)
GO_REF:0000107

GO_REF:0000107

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

Gbp7

guanylate binding protein 7

involved_in

ISO
IEA

(PMID:24739961)
GO_REF:0000107

GO_REF:0000107

NCBI chr 2:231,275,521...231,297,289
Ensembl chr 2:231,275,640...231,297,278

Hexim1

HEXIM P-TEFb complex subunit 1

involved_in

ISO

(PMID:28712728)

NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189

high mobility group box 1

involved_in

ISO

(PMID:24971542)

PMID:24971542

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

Hsp90aa1

heat shock protein 90 alpha family class A member 1

involved_in

ISO
IEA
ISS

(PMID:20628368)
GO_REF:0000107
GO_REF:0000024

PMID:20628368

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

Ifi214

interferon activated gene 214

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr13:85,940,028...85,951,004
Ensembl chr13:85,940,078...85,951,004

Ikbke

inhibitor of nuclear factor kappa B kinase subunit epsilon

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

LOC102556096

pyrin domain-containing protein 3-like

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033

NCBI chr13:85,911,915...85,929,491
Ensembl chr13:85,912,044...85,929,007

Matr3

matrin 3

involved_in

ISO

(PMID:28712728)

NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166

mitochondrial antiviral signaling protein

involved_in

ISS
ISO

GO_REF:0000024
(PMID:20628368)

PMID:20628368

GO_REF:0000024

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

Mnda

myeloid cell nuclear differentiation antigen

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033

NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201

Nlrc4

NLR family, CARD domain containing 4

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:16648852)

PMID:16648852

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248

Nlrp10

NLR family, pyrin domain containing 10

involved_in

ISO

(PMID:22672233)

PMID:22672233

NCBI chr 1:162,922,806...162,930,363
Ensembl chr 1:162,922,806...162,930,363

NLR family, pyrin domain containing 1A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180

Nlrp1b

NLR family, pyrin domain containing 1B

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774

Nono

non-POU domain containing, octamer-binding

involved_in

ISO
IEA

(PMID:28712728)
GO_REF:0000107

GO_REF:0000107

NCBI chr X:66,554,131...66,571,992
Ensembl chr X:66,554,098...66,571,952

Pqbp1

polyglutamine binding protein 1

involved_in

ISO
IEA
ISS

(PMID:26046437)
GO_REF:0000107
GO_REF:0000024

PMID:26046437

GO_REF:0000024 GO_REF:0000107

NCBI chr X:14,603,516...14,608,091
Ensembl chr X:14,603,539...14,608,087

Prkdc

protein kinase, DNA-activated, catalytic subunit

involved_in

ISO

(PMID:28712728)

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

Pspc1

paraspeckle component 1

involved_in

ISO

(PMID:28712728)

NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202

Pycard

PYD and CARD domain containing

involved_in

ISO
IEA
IBA

(PMID:19158675)
GO_REF:0000107
GO_REF:0000033

PMID:19158675

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

Rbm14

RNA binding motif protein 14

involved_in

ISO
IEA

(PMID:28712728)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665
Ensembl chr 1:202,078,287...202,105,665

Sfpq

splicing factor proline and glutamine rich

involved_in

ISO
IEA

(PMID:28712728)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472

Sin3a

SIN3 transcription regulator family member A

involved_in

ISO
IEA

(PMID:22783022)
GO_REF:0000107

PMID:22783022

GO_REF:0000107

NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192

GO_Central
RGD
InterPro
Ensembl

stimulator of interferon response cGAMP interactor 1

involved_in

IBA
ISO
IEA

GO_REF:0000033
(PMID:23910378)
GO_REF:0000002
GO_REF:0000107
(PMID:21947006), (PMID:23258412), (PMID:23910378)

PMID:21947006 PMID:23258412 PMID:23910378

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

TANK-binding kinase 1

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:25636800)
GO_REF:0000107
GO_REF:0000033
MGI:3046789 (PMID:15661922)

PMID:15661922 PMID:25636800

GO_REF:0000033 GO_REF:0000107

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

toll-like receptor 4

acts_upstream_of_or_within

ISO
IEA

MGI:1860885 (PMID:15661922)
GO_REF:0000107

PMID:15661922

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

toll-like receptor 9

involved_in

ISO
IEA

(PMID:25686612)
GO_REF:0000107

PMID:25686612

GO_REF:0000107

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Tomm70

translocase of outer mitochondrial membrane 70

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:20628368)

PMID:20628368

GO_REF:0000024 GO_REF:0000107

NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202

Trim5

tripartite motif-containing 5

involved_in

ISO

(PMID:21512573)

PMID:21512573

NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:158,720,410...158,814,012

Xrcc5

X-ray repair cross complementing 5

involved_in

ISO

(PMID:28712728)

NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018

Xrcc6

X-ray repair cross complementing 6

involved_in

ISO
IEA

(PMID:28712728)
GO_REF:0000107

GO_REF:0000107

NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762

Z-DNA binding protein 1

involved_in

ISS
ISO

GO_REF:0000024
(PMID:32200799), (PMID:32296175), (PMID:32350114), (PMID:33109609)

PMID:32200799 PMID:32296175 PMID:32350114 PMID:33109609

GO_REF:0000024

NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:161,993,351...162,003,870

Zcchc3

zinc finger CCHC-type containing 3

involved_in

ISO
IEA
IBA

(PMID:30135424), (PMID:30193849)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033

RGD
Ensembl
InterPro
GO_Central

PMID:30135424 PMID:30193849

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr 3:140,872,460...140,875,292
Ensembl chr 3:140,872,460...140,882,408

Znfx1

zinc finger, NFX1-type containing 1

involved_in

ISO
IEA

(PMID:31685995)
GO_REF:0000107

PMID:31685995

GO_REF:0000107

NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242

antibacterial humoral response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

angiogenin

involved_in

ISO

(PMID:12548285)

NCBI chr15:24,312,711...24,323,361

Ang2

angiogenin, ribonuclease A family, member 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,398,330...24,415,909
Ensembl chr15:24,398,419...24,398,922

amyloid beta precursor protein

involved_in

IDA

PMID:20209079

UniProt

PMID:20209079

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

Bpifa1

BPI fold containing family A, member 1

involved_in

ISO
IBA
ISS

(PMID:23499554)
GO_REF:0000033
GO_REF:0000024

PMID:23499554

GO_REF:0000024 GO_REF:0000033

NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552

Bpifa5

BPI fold containing family A, member 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883

cathelicidin antimicrobial peptide

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

Ctsg

cathepsin G

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353

Defa24

defensin alpha 24

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,349,550...70,350,582
Ensembl chr16:70,349,567...70,350,603

Defa3

defensin alpha 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,533,436...70,535,592
Ensembl chr16:70,533,436...70,535,604

Defa31

defensin alpha 31

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,513,892...70,516,234
Ensembl chr16:70,514,248...70,515,024

defensin alpha 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836

Defa6

defensin alpha 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,405,223...70,406,237
Ensembl chr16:70,405,268...70,406,142

Defa8

defensin alpha 8

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,433,121...70,434,154
Ensembl chr16:70,433,166...70,434,059

Defa9

defensin alpha 9

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,481,813...70,482,803
Ensembl chr16:70,481,821...70,482,717

Defal1

defensin alpha-like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,371,492...70,372,481
Ensembl chr16:70,371,518...70,372,353

ENSRNOG00000064390

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr16:70,426,027...70,475,448

ENSRNOG00000065917

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 6:132,469,837...132,473,735

ENSRNOG00000070986

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 6:132,341,443...132,343,215

Igg-2a

gamma-2a immunoglobulin heavy chain

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Igh-6

immunoglobulin heavy chain 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ighg1

immunoglobulin heavy constant gamma 1

acts_upstream_of_or_within
involved_in

ISO
IBA

(PMID:11911824), (PMID:9834074)
GO_REF:0000033

PMID:9834074 PMID:11911824

GO_REF:0000033

Ensembl chr 6:132,389,370...132,393,397

Inhca

inhibitor of carbonic anhydrase

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 8:103,836,846...103,874,980
Ensembl chr 8:103,823,196...103,874,985

Jchain

joining chain of multimeric IgA and IgM

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298

lactotransferrin

involved_in

ISO
IBA

(PMID:1599934), (PMID:18714013)
GO_REF:0000033

PMID:1599934 PMID:18714013

GO_REF:0000033

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

defensin NP-4 precursor

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,494,607...70,497,261
Ensembl chr16:70,342,529...70,497,202

Pla2g6

phospholipase A2 group VI

involved_in

ISO

(PMID:18714013)

PMID:18714013

NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114

Ratnp-3b

defensin rat NP-3 precursor

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,544,364...70,546,533
Ensembl chr16:70,513,888...70,546,522

Rnase4

ribonuclease A family member 4

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:30418175)
(PMID:33818125)

PMID:30418175 PMID:33818125

GO_REF:0000024 GO_REF:0000107

NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117

Rnase6

ribonuclease A family member 6

involved_in

ISO
IBA

(PMID:25075772)
GO_REF:0000033

PMID:25075772

GO_REF:0000033

NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328

Semg1

semenogelin 1

involved_in

ISO

(PMID:18714013)

PMID:18714013

NCBI chr 3:152,910,033...152,912,882
Ensembl chr 3:152,910,034...152,912,882

Slpi

secretory leukocyte peptidase inhibitor

involved_in

ISO

(PMID:18714013)
(PMID:18322212)

PMID:18322212 PMID:18714013

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

Slpi-ps1

secretory leukocyte peptidase inhibitor, pseudogene 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,019,109...153,021,371
Ensembl chr 3:153,019,109...153,021,360
Ensembl chr 3:153,019,109...153,021,360

Slpi-ps2

secretory leukocyte peptidase inhibitor, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,056,907...153,061,611
Ensembl chr 3:153,019,114...153,059,479
Ensembl chr 3:153,019,114...153,059,479

Spag11a

sperm associated antigen 11A

acts_upstream_of_or_within

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr16:70,682,326...70,684,067
Ensembl chr16:70,682,326...70,684,069

Sprr2a

small proline rich protein 2A

involved_in

ISO

(PMID:34735226)

PMID:34735226

NCBI chr 2:177,815,964...177,816,236
Ensembl chr 2:177,815,964...177,816,236

transferrin

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511

Wap

whey acidic protein

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr14:81,503,123...81,505,244
Ensembl chr14:81,503,123...81,505,219

Wfdc10a

WAP four-disulfide core domain 10A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,390,067...153,391,420
Ensembl chr 3:153,390,067...153,391,420

Wfdc12

WAP four-disulfide core domain 12

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:152,861,461...152,862,784
Ensembl chr 3:152,862,341...152,862,690

Wfdc13

WAP four-disulfide core domain 13

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,419,553...153,421,306
Ensembl chr 3:153,419,648...153,421,221

Wfdc15b

WAP four-disulfide core domain 15B

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:152,889,453...152,899,392
Ensembl chr 3:152,890,216...152,896,900

Wfdc16

WAP four-disulfide core domain 16

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,366,913...153,370,083
Ensembl chr 3:153,366,976...153,370,056

Wfdc17

WAP four-disulfide core domain 17

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801

Wfdc18

WAP four-disulfide core domain 18

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,588,818...68,590,972
Ensembl chr10:68,588,818...68,589,671

Wfdc2

WAP four-disulfide core domain 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,286,946...153,314,832
Ensembl chr 3:153,286,131...153,292,807

Wfdc21

WAP four-disulfide core domain 21

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,627,836...68,633,705
Ensembl chr10:68,627,820...68,633,701

Wfdc3

WAP four-disulfide core domain 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,464,862...153,478,952
Ensembl chr 3:153,464,862...153,478,952

Wfdc5

WAP four-disulfide core domain 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:152,849,025...152,854,868
Ensembl chr 3:152,849,025...152,854,904

Wfdc9

WAP four-disulfide core domain 9

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,380,554...153,389,055
Ensembl chr 3:153,380,649...153,391,261

antibacterial innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Defb44

defensin beta 44

involved_in

ISO

(PMID:34481960)

PMID:34481960

NCBI chr15:37,311,888...37,313,579
Ensembl chr15:37,312,308...37,313,370

Il33

interleukin 33

involved_in

ISO

(PMID:26936882)

PMID:26936882

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

Marchf2

membrane associated ring-CH-type finger 2

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:32935379)

PMID:32935379

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:15,183,931...15,209,988
Ensembl chr 7:14,481,761...14,507,794

Mirlet7b

microRNA let-7b

involved_in

ISO

(PMID:29471394)

PMID:29471394

NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270

Mpeg1

macrophage expressed 1

involved_in
NOT|involved_in

ISS
ISO

GO_REF:0000024
(PMID:35471730)
(PMID:26402460)

PMID:26402460 PMID:35471730

GO_REF:0000024

NCBI chr 1:209,452,176...209,456,692
Ensembl chr 1:209,452,133...209,458,855

Muc19

mucin 19, oligomeric

acts_upstream_of_or_within

ISO

(PMID:25512380)

PMID:25512380

NCBI chr 7:123,017,896...123,139,053
Ensembl chr 7:123,017,896...123,139,053

Nfkb1

nuclear factor kappa B subunit 1

involved_in

IEA
ISO

GO_REF:0000107
(PMID:20406817)

PMID:20406817

GO_REF:0000107

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

nucleotide-binding oligomerization domain containing 2

involved_in

ISO
IEA

(PMID:20406817)
GO_REF:0000107

PMID:20406817

GO_REF:0000107

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Rasgrp4

RAS guanyl releasing protein 4

involved_in

ISS
ISO

GO_REF:0000024
(PMID:26982501)

PMID:26982501

GO_REF:0000024

NCBI chr 1:84,433,033...84,452,841
Ensembl chr 1:84,433,064...84,451,896

Slc15a2

solute carrier family 15 member 2

involved_in

IEA
ISO

GO_REF:0000107
(PMID:20406817)

PMID:20406817

GO_REF:0000107

NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225

Tfeb

transcription factor EB

involved_in

ISO
IEA

(PMID:32753672), (PMID:35662396)
GO_REF:0000107

PMID:32753672 PMID:35662396

GO_REF:0000107

NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714

Umod

uromodulin

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:32616672)

PMID:32616672

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302

antibacterial peptide biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lgals4

galectin 4

acts_upstream_of_or_within

ISO
IEA

(PMID:27427436)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481

Mmp7

matrix metallopeptidase 7

acts_upstream_of_or_within

ISO
IEA

(PMID:20056603)
GO_REF:0000107

PMID:20056603

GO_REF:0000107

NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902

antibacterial peptide secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mmp7

matrix metallopeptidase 7

acts_upstream_of_or_within

ISO
IEA

(PMID:11248802)
GO_REF:0000107

PMID:11248802

GO_REF:0000107

NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902

antifungal humoral response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

angiogenin

involved_in

ISO

(PMID:12548285)

NCBI chr15:24,312,711...24,323,361

amyloid beta precursor protein

involved_in

IDA

PMID:20209079

UniProt

PMID:20209079

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

Fam3a

FAM3 metabolism regulating signaling molecule A

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362

Il36rn

interleukin 36 receptor antagonist

involved_in

ISO
IEA

(PMID:23147407)
GO_REF:0000107

PMID:23147407

GO_REF:0000107

NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016

Rarres2

retinoic acid receptor responder 2

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556

Spag11a

sperm associated antigen 11A

acts_upstream_of_or_within

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr16:70,682,326...70,684,067
Ensembl chr16:70,682,326...70,684,069

antifungal innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcl10

BCL10, immune signaling adaptor

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:22265677)

PMID:22265677

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

Card9

caspase recruitment domain family, member 9

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:22265677), (PMID:24470469), (PMID:25621893), (PMID:26679537), (PMID:29080677), (PMID:32358020), (PMID:33548172)
(PMID:24231284), (PMID:25057046), (PMID:25702837), (PMID:26488816), (PMID:26679537), (PMID:26961233), (PMID:29080677), (PMID:33548172), (PMID:33558980)

PMID:22265677 PMID:24231284 PMID:24470469 PMID:25057046 PMID:25621893 More...

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237

Clec4a

C-type lectin domain family 4, member A

involved_in

IBA
ISO

GO_REF:0000033
(PMID:22041900), (PMID:32358020)

PMID:22041900 PMID:32358020

GO_REF:0000033

NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402

Clec4a1

C-type lectin domain family 4, member A1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:156,173,894...156,186,009
Ensembl chr 4:156,173,894...156,186,008

Clec4a2

C-type lectin domain family 4, member A2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:156,262,438...156,321,695
Ensembl chr 4:156,262,692...156,321,392

Clec4a3

C-type lectin domain family 4, member A3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817

Clec4b2

C-type lectin domain family 4, member B2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:156,462,742...156,486,240
Ensembl chr 4:156,462,742...156,486,240

Clec4d

C-type lectin domain family 4, member D

involved_in

ISO
IBA
ISS

(PMID:23911656)
GO_REF:0000033
GO_REF:0000024

UniProt
RGD
GO_Central
Ensembl

PMID:23911656

GO_REF:0000024 GO_REF:0000033

NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848

Clec4e

C-type lectin domain family 4, member E

involved_in

ISS
ISO
IBA
IEA

GO_REF:0000024
(PMID:18490740)
GO_REF:0000033
GO_REF:0000107

PMID:18490740

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767

Clec6a-ps1

C-type lectin domain family 6, member A, pseudogene 1

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000107

GO_Central
Ensembl

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:156,539,408...156,559,032
Ensembl chr 4:156,539,408...156,558,605
Ensembl chr 4:156,539,408...156,558,605

C-type lectin domain containing 7A

involved_in

ISO

(PMID:17159984), (PMID:19136564), (PMID:32358020)

PMID:17159984 PMID:19136564 PMID:32358020

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

Cx3cr1

C-X3-C motif chemokine receptor 1

involved_in

ISS
ISO

GO_REF:0000024
(PMID:29326275)

PMID:29326275

GO_REF:0000024

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

Defb4

defensin beta 4

involved_in

ISO

(PMID:30050988)

PMID:30050988

NCBI chr16:70,650,472...70,653,665
Ensembl chr16:70,650,472...70,653,665

Defb44

defensin beta 44

involved_in

ISO

(PMID:34481960)

PMID:34481960

NCBI chr15:37,311,888...37,313,579
Ensembl chr15:37,312,308...37,313,370

Defb5

defensin beta 5

involved_in

ISO

(PMID:30050988)

PMID:30050988

NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467

phospholipase C, gamma 2

involved_in

ISO

(PMID:22041900)

PMID:22041900

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Rarres2

retinoic acid receptor responder 2

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556

antimicrobial humoral immune response mediated by antimicrobial peptide

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adm

adrenomedullin

involved_in

ISO

(PMID:10225288)

PMID:10225288

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

angiogenin

involved_in

ISO

(PMID:12548285)

NCBI chr15:24,312,711...24,323,361

Ang2

angiogenin, ribonuclease A family, member 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,398,330...24,415,909
Ensembl chr15:24,398,419...24,398,922

amyloid beta precursor protein

involved_in

IDA
ISO

PMID:20209079
(PMID:20209079)

PMID:20209079 PMID:20209079

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

B2m

beta-2 microglobulin

involved_in

ISO

(PMID:23144825)

PMID:23144825

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766

Bpifa1

BPI fold containing family A, member 1

involved_in

ISO
IBA

(PMID:21805676)
GO_REF:0000033

PMID:21805676

GO_REF:0000033

NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552

Bpifa5

BPI fold containing family A, member 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883

Calca

calcitonin-related polypeptide alpha

involved_in

ISO

(PMID:18603306)

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

cathelicidin antimicrobial peptide

involved_in

ISO
IEA
IBA

(PMID:12860195)
GO_REF:0000107
GO_REF:0000033
(PMID:17012259)
(PMID:7529412)
(PMID:12759353), (PMID:14978112), (PMID:17012259), (PMID:20209079), (PMID:20421939), (PMID:23537644), (PMID:9182550)

PMID:7529412 PMID:9182550 PMID:12759353 PMID:12860195 PMID:14978112 More...

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

Ccl1

C-C motif chemokine ligand 1

involved_in

ISO
IBA

(PMID:12949249)
GO_REF:0000033

GO_REF:0000033

NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159

Ccl11

C-C motif chemokine ligand 11

involved_in

ISO
IBA

(PMID:12949249)
GO_REF:0000033

GO_REF:0000033

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

Ccl12

C-C motif chemokine ligand 12

involved_in

ISO
IBA

(PMID:12949249)
GO_REF:0000033

GO_REF:0000033

NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780

Ccl17

C-C motif chemokine ligand 17

involved_in

ISO

(PMID:12949249)

NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819

Ccl19

C-C motif chemokine ligand 19

involved_in

ISO
IBA

(PMID:12949249)
GO_REF:0000033

GO_REF:0000033

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

Ccl2

C-C motif chemokine ligand 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

Ccl20

C-C motif chemokine ligand 20

involved_in

ISO

(PMID:12949249), (PMID:19109182)

PMID:12949249 PMID:19109182

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

Ccl21

C-C motif chemokine ligand 21

involved_in

ISO

(PMID:12949249)

NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686

Ccl22

C-C motif chemokine ligand 22

involved_in

ISO

(PMID:12949249)

NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400

Ccl24

C-C motif chemokine ligand 24

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893

Ccl25

C-C motif chemokine ligand 25

involved_in

ISO
IBA

(PMID:12949249)
GO_REF:0000033

GO_REF:0000033

NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554

Ccl27

C-C motif chemokine ligand 27

involved_in

ISO
IBA

(PMID:19109182)
GO_REF:0000033

PMID:19109182

GO_REF:0000033

NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506

Ccl28

C-C motif chemokine ligand 28

involved_in

ISO

(PMID:12538707)

PMID:12538707

NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997

Ccl3

C-C motif chemokine ligand 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

Ccl4

C-C motif chemokine ligand 4

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

Ccl5

C-C motif chemokine ligand 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

Ccl6

C-C motif chemokine ligand 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,380,185...68,385,859
Ensembl chr10:68,380,188...68,384,001

Ccl7

C-C motif chemokine ligand 7

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

Ccl9

C-C motif chemokine ligand 9

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

Cx3cl1

C-X3-C motif chemokine ligand 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

Cxcl1

C-X-C motif chemokine ligand 1

involved_in

ISO

(PMID:12949249)

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

Cxcl10

C-X-C motif chemokine ligand 10

involved_in

ISO

(PMID:12949249)

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

Cxcl11

C-X-C motif chemokine ligand 11

involved_in

ISO

(PMID:12949249)

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

Cxcl12

C-X-C motif chemokine ligand 12

involved_in

ISO

(PMID:12949249)

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

Cxcl13

C-X-C motif chemokine ligand 13

involved_in

ISO
IBA

(PMID:12949249)
GO_REF:0000033

GO_REF:0000033

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

Cxcl14

C-X-C motif chemokine ligand 14

involved_in

ISO

(PMID:12949249), (PMID:19109182)
(PMID:19109182)

PMID:12949249 PMID:19109182

NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839

Cxcl2

C-X-C motif chemokine ligand 2

involved_in

ISO

(PMID:12949249)

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

Cxcl3

C-X-C motif chemokine ligand 3

involved_in

ISO

(PMID:12949249)

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

Cxcl6

C-X-C motif chemokine ligand 6

involved_in

ISO
IBA
IEA

(PMID:8399143)
GO_REF:0000033
GO_REF:0000107

PMID:8399143

GO_REF:0000033 GO_REF:0000107

NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093

Cxcl9

C-X-C motif chemokine ligand 9

involved_in

ISO

(PMID:12949249)

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

Defa24

defensin alpha 24

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,349,550...70,350,582
Ensembl chr16:70,349,567...70,350,603

Defa3

defensin alpha 3

involved_in

IBA
ISO

GO_REF:0000033
(PMID:12860195)

GO_REF:0000033

NCBI chr16:70,533,436...70,535,592
Ensembl chr16:70,533,436...70,535,604

Defa31

defensin alpha 31

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,513,892...70,516,234
Ensembl chr16:70,514,248...70,515,024

defensin alpha 5

involved_in

ISO
IBA

(PMID:12660734), (PMID:25782105)
GO_REF:0000033

PMID:12660734 PMID:25782105

GO_REF:0000033

NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836

Defa6

defensin alpha 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,405,223...70,406,237
Ensembl chr16:70,405,268...70,406,142

Defa8

defensin alpha 8

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,433,121...70,434,154
Ensembl chr16:70,433,166...70,434,059

Defa9

defensin alpha 9

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,481,813...70,482,803
Ensembl chr16:70,481,821...70,482,717

Defal1

defensin alpha-like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,371,492...70,372,481
Ensembl chr16:70,371,518...70,372,353

Defb1

defensin beta 1

involved_in

ISO

(PMID:12860195), (PMID:25122636)

PMID:12860195 PMID:25122636

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

Defb14

defensin beta 14

involved_in

ISO

(PMID:11085990)

PMID:11085990

NCBI chr16:70,663,443...70,668,473
Ensembl chr16:70,663,333...70,666,540

Defb21

defensin beta 21

involved_in

ISO

(PMID:15033915)

PMID:15033915

NCBI chr 3:141,042,810...141,044,228
Ensembl chr 3:141,042,810...141,044,184

Defb22

defensin beta 22

involved_in

ISO

(PMID:19373462)

PMID:19373462

NCBI chr 3:140,957,093...140,961,373
Ensembl chr 3:140,957,090...140,961,373

Defb4

defensin beta 4

involved_in

ISO

(PMID:30050988), (PMID:9727055)
(PMID:19109182)

PMID:9727055 PMID:19109182 PMID:30050988

NCBI chr16:70,650,472...70,653,665
Ensembl chr16:70,650,472...70,653,665

Defb43

defensin beta 43

involved_in

ISO

(PMID:26649771)

PMID:26649771

NCBI chr15:37,271,888...37,276,782
Ensembl chr15:37,272,008...37,276,626

Defb5

defensin beta 5

involved_in

ISO

(PMID:30050988), (PMID:9727055)
(PMID:19109182)

PMID:9727055 PMID:19109182 PMID:30050988

NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467

Dmbt1

deleted in malignant brain tumors 1

involved_in

ISO

(PMID:11007786)

PMID:11007786

NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478

ENSRNOG00000064390

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr16:70,426,027...70,475,448

coagulation factor II, thrombin

involved_in

IEA
ISO

GO_REF:0000107
(PMID:20421939)

PMID:20421939

GO_REF:0000107

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

Fam3a

FAM3 metabolism regulating signaling molecule A

involved_in

ISO
IEA

(PMID:18212107)
GO_REF:0000107

PMID:18212107

GO_REF:0000107

NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362

Fau

FAU ubiquitin like and ribosomal protein S30 fusion

involved_in

ISO

(PMID:12860195)
(PMID:10496312)

PMID:10496312 PMID:12860195

NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
Ensembl chr 1:203,350,189...203,351,742
Ensembl chr 6:203,350,189...203,351,742

Galp

galanin-like peptide

involved_in

ISO

(PMID:23537644)

PMID:23537644

NCBI chr 1:67,684,023...67,703,121
Ensembl chr 1:67,684,025...67,702,269

Gapdh

glyceraldehyde-3-phosphate dehydrogenase

involved_in

ISO

(PMID:22832495)

PMID:22832495

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

H2bc12

H2B clustered histone 12

involved_in

ISO

(PMID:12860195), (PMID:15019208)

PMID:12860195 PMID:15019208

NCBI chr17:42,485,699...42,486,162

H2bc18

H2B clustered histone 18

involved_in

ISO

(PMID:12860195)

NCBI chr 2:183,838,331...183,842,769
Ensembl chr 2:183,838,334...183,841,529

H2bc3

H2B clustered histone 3

involved_in

ISO

(PMID:12860195)

NCBI chr17:41,380,056...41,380,686

H2bc6

H2B clustered histone 6

involved_in

ISO

(PMID:12860195)

NCBI chr17:41,520,775...41,521,238

H2bc8

H2B clustered histone 8

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,708,658...42,709,408

H2bc9

H2B clustered histone 9

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,470,593...42,478,590

H2bu1

H2B.U histone 1

involved_in

ISO

(PMID:12860195)

NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277

Hamp

hepcidin antimicrobial peptide

involved_in

ISO

(PMID:11034317)
(PMID:11113131)

PMID:11034317 PMID:11113131

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

Hist1h2bc

histone cluster 1, H2bc

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642

Hist1h2bd

histone cluster 1 H2B family member D

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,792,887...42,793,268

Hist1h2bq

histone cluster 1 H2B family member Q

involved_in

ISO

(PMID:12860195)

NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153
Ensembl chr17:41,429,164...41,442,153
Ensembl chr17:41,429,164...41,442,153

Hist2h2be

histone cluster 2 H2B family member E

involved_in

ISO

(PMID:11859126), (PMID:12860195)

PMID:11859126 PMID:12860195

NCBI chr 2:183,780,583...183,783,030

Hmgn2

high mobility group nucleosomal binding domain 2

involved_in

ISO

(PMID:16204630)

PMID:16204630

NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
Ensembl chr16:146,192,126...146,195,521

Hrg

histidine-rich glycoprotein

involved_in

ISO
IBA

(PMID:18797515)
GO_REF:0000033

PMID:18797515

GO_REF:0000033

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

Hrgl1

histidine-rich glycoprotein like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353

Leap2

liver enriched antimicrobial peptide 2

involved_in

ISO

(PMID:12493837)

PMID:12493837

NCBI chr10:37,580,172...37,581,244
Ensembl chr10:37,577,855...37,581,244

Lgals3

galectin 3

involved_in

ISO

(PMID:16982911)

PMID:16982911

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

lactotransferrin

involved_in

ISO

(PMID:15155221)

PMID:15155221

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

defensin NP-4 precursor

involved_in

ISO
IBA

(PMID:2500436)
GO_REF:0000033

PMID:2500436

GO_REF:0000033

NCBI chr16:70,494,607...70,497,261
Ensembl chr16:70,342,529...70,497,202

Nppb

natriuretic peptide B

involved_in

ISO

(PMID:11410403)

PMID:11410403

NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168

Npy

neuropeptide Y

involved_in

ISO

(PMID:18603306)

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

Pf4

platelet factor 4

involved_in

ISO
IEA
IBA

(PMID:10877842)
GO_REF:0000107
GO_REF:0000033
(PMID:23245326)

PMID:10877842 PMID:23245326

GO_REF:0000033 GO_REF:0000107

NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365

Pglyrp1

peptidoglycan recognition protein 1

involved_in

ISO

(PMID:16354652)

PMID:16354652

NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001

Pglyrp3

peptidoglycan recognition protein 3

involved_in

ISO

(PMID:16354652)

PMID:16354652

NCBI chr 2:177,479,693...177,490,769
Ensembl chr 2:177,477,407...177,490,736
Ensembl chr 2:177,477,407...177,490,736

Pglyrp4

peptidoglycan recognition protein 4

involved_in

ISO
IEA

(PMID:16354652)
GO_REF:0000107

PMID:16354652

GO_REF:0000107

NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251

Pla2g1b

phospholipase A2 group IB

involved_in

ISO

(PMID:12860195)

NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226

Ppbp

pro-platelet basic protein

involved_in

ISO

(PMID:10877842)

PMID:10877842

NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130

Ratnp-3b

defensin rat NP-3 precursor

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,544,364...70,546,533
Ensembl chr16:70,513,888...70,546,522

Reg1a

regenerating family member 1 alpha

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570

Reg3a

regenerating islet-derived 3 alpha

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:110,872,398...110,875,157
Ensembl chr 4:110,872,425...110,875,157

Reg3b

regenerating family member 3 beta

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015

Reg3g

regenerating family member 3 gamma

involved_in

ISO
IEA
IBA

(PMID:16931762)
GO_REF:0000107
GO_REF:0000033

PMID:16931762

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723

Rnase3

ribonuclease A family member 3

involved_in

ISO

(PMID:12860195)

NCBI chr15:24,511,894...24,512,764
Ensembl chr15:24,511,891...24,512,790

Rnase6

ribonuclease A family member 6

involved_in

ISO
IBA

(PMID:25075772)
GO_REF:0000033

PMID:25075772

GO_REF:0000033

NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328

Romo1

reactive oxygen species modulator 1

involved_in

ISO
IEA

(PMID:22083756)
GO_REF:0000107

PMID:22083756

GO_REF:0000107

NCBI chr 3:144,659,709...144,661,310
Ensembl chr 3:144,659,826...144,661,310

Rpl30

ribosomal protein L30

involved_in

ISO

(PMID:15019208)

PMID:15019208

NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr 1:65,645,991...65,651,363

Rpl39

ribosomal protein L39

involved_in

ISO

(PMID:12860195)

NCBI chr  X:116,327,216...116,330,211
Ensembl chr18:6,326,330...6,326,692
Ensembl chr  X:6,326,330...6,326,692
Ensembl chr  X:6,326,330...6,326,692
Ensembl chr15:6,326,330...6,326,692
Ensembl chr20:6,326,330...6,326,692
Ensembl chr 7:6,326,330...6,326,692

Rps19

ribosomal protein S19

involved_in

ISO

(PMID:15019208)

PMID:15019208

NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508

S100a9

S100 calcium binding protein A9

involved_in

IEA
IBA

GO_REF:0000107
GO_REF:0000033

Ensembl
GO_Central

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

Spag11b

sperm associated antigen 11B

involved_in

ISO

(PMID:16411022)

PMID:16411022

NCBI chr16:70,697,810...70,700,336
Ensembl chr16:70,698,127...70,700,110

Tac1

tachykinin, precursor 1

involved_in

ISO

(PMID:18603306)

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

Tslp

thymic stromal lymphopoietin

involved_in

ISO

(PMID:24850429)

PMID:24850429

NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548

Vip

vasoactive intestinal peptide

involved_in

ISO

(PMID:18603306)

NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216

Xcl1

X-C motif chemokine ligand 1

involved_in

ISO
IBA

(PMID:12949249)
GO_REF:0000033

GO_REF:0000033

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

antimicrobial humoral response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcl3

BCL3, transcription coactivator

acts_upstream_of_or_within

ISO

MGI:1861796 (PMID:9009202)

PMID:9009202

NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607

Colec11

collectin sub-family member 11

involved_in

ISO

(PMID:20956340)

PMID:20956340

NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145

Cst9l

cystatin 9-like

involved_in

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
(PMID:23922243)

PMID:23922243

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:136,288,093...136,290,906
Ensembl chr 3:136,288,093...136,290,906

Cstdc2

cystatin domain containing 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:136,302,588...136,336,782
Ensembl chr 3:136,305,152...136,308,899

antiviral innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Akap1

A-kinase anchoring protein 1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:31522117)

GO_REF:0000024 GO_REF:0000107

NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896

Atad3a

ATPase family, AAA domain containing 3A

involved_in

ISO
IEA
ISS

(PMID:31522117)
GO_REF:0000107
GO_REF:0000024

GO_REF:0000024 GO_REF:0000107

NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482

Clpb

ClpB family mitochondrial disaggregase

involved_in

ISO

(PMID:31522117)

NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788

Cxcl10

C-X-C motif chemokine ligand 10

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

Dhx15

DEAH-box helicase 15

involved_in

ISO
IEA

(PMID:24990078)
GO_REF:0000107
(PMID:26494172), (PMID:34678144)

PMID:24990078 PMID:26494172 PMID:34678144

GO_REF:0000107

NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088

Dhx16

DEAH-box helicase 16

involved_in

ISO
IEA

(PMID:35263596)
GO_REF:0000107

PMID:35263596

GO_REF:0000107

NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948

DEXH-box helicase 58

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Dus2

dihydrouridine synthase 2

involved_in

ISO

UniProtKB:P19525 (PMID:18096616)

PMID:18096616

NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709

Eif2ak2

eukaryotic translation initiation factor 2-alpha kinase 2

involved_in

IEA
ISO

GO_REF:0000107
(PMID:22948139)

PMID:22948139

GO_REF:0000107

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

Hcfc2

host cell factor C2

acts_upstream_of_or_within

ISO

MGI:5445585 (PMID:28970238)

PMID:28970238

NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801

Hdac6

histone deacetylase 6

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr X:17,222,538...17,244,373
Ensembl chr X:14,551,044...14,572,441

interferon induced with helicase C domain 1

involved_in
acts_upstream_of_or_within

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
MGI:3663677 (PMID:28031478)

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

Ifit2

interferon-induced protein with tetratricopeptide repeats 2

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:19416887)
GO_REF:0000107
(PMID:31390091)

PMID:19416887 PMID:31390091

GO_REF:0000107

NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635

Ifit3

interferon-induced protein with tetratricopeptide repeats 3

involved_in

ISO

(PMID:21642987)

PMID:21642987

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

interferon regulatory factor 3

involved_in

ISO

(PMID:9891032)

PMID:9891032

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

Marchf2

membrane associated ring-CH-type finger 2

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:32935379)

PMID:32935379

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:15,183,931...15,209,988
Ensembl chr 7:14,481,761...14,507,794

mitochondrial antiviral signaling protein

involved_in

ISO

(PMID:27992402)

PMID:27992402

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

mannose binding lectin 2

involved_in

ISO

(PMID:35102342)

PMID:35102342

NCBI chr 1:228,016,439...228,024,736

Morc3

MORC family CW-type zinc finger 3

involved_in

ISO
IEA

(PMID:27440897)
GO_REF:0000107

PMID:27440897

GO_REF:0000107

NCBI chr11:33,151,906...33,194,650
Ensembl chr11:33,152,025...33,194,646

Nck1

NCK adaptor protein 1

involved_in

ISO
IEA

(PMID:18835251)
GO_REF:0000107

PMID:18835251

GO_REF:0000107

NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300

NLR family, pyrin domain containing 1A

involved_in

ISO

(PMID:33093214)

PMID:33093214

NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180

NLR family, pyrin domain containing 6

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:26494172), (PMID:34678144)
GO_REF:0000107
(PMID:34161762)

PMID:26494172 PMID:34161762 PMID:34678144

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113

Nmb

neuromedin B

involved_in

ISO

(PMID:31601264)

PMID:31601264

NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190

Nmbr

neuromedin B receptor

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:31601264)

PMID:31601264

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462

2'-5' oligoadenylate synthetase 1A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

Oas1b

2-5 oligoadenylate synthetase 1B

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242

Oas1d

2'-5' oligoadenylate synthetase 1D

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,648,583...35,658,037
Ensembl chr12:35,648,583...35,657,902

Oas1e

2'-5' oligoadenylate synthetase 1E

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,750,359...35,759,304
Ensembl chr12:35,750,359...35,759,301

Oas1h

2 ' -5 ' oligoadenylate synthetase 1H

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,682,862...35,695,717
Ensembl chr12:35,683,699...35,693,366

Oas1i

2 ' -5 ' oligoadenylate synthetase 1I

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604

Oas2

2'-5' oligoadenylate synthetase 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371

2'-5'-oligoadenylate synthetase 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781

2'-5'-oligoadenylate synthetase-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641

Oasl2

2'-5' oligoadenylate synthetase-like 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:41,710,072...41,722,687
Ensembl chr12:41,709,435...41,722,547

Otud4

OTU deubiquitinase 4

involved_in

ISO

(PMID:36943869)

PMID:36943869

NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815

Pde12

phosphodiesterase 12

involved_in

ISO
IEA

(PMID:15231837)
GO_REF:0000107

PMID:15231837

GO_REF:0000107

NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887

Phb1

prohibitin 1

involved_in

ISO

(PMID:31522117)

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

Phb2

prohibitin 2

involved_in

ISO
IEA

(PMID:31522117)
GO_REF:0000107

GO_REF:0000107

NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272

Prkra

protein activator of interferon induced protein kinase EIF2AK2

involved_in

IEA
ISO

GO_REF:0000107
(PMID:26454002)

PMID:26454002

GO_REF:0000107

NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347

RELA proto-oncogene, NF-kB subunit

involved_in

ISO
IEA

(PMID:38114488)
GO_REF:0000107

PMID:38114488

GO_REF:0000107

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

RNA sensor RIG-1

involved_in

ISO
IEA
IBA

(PMID:28469175)
GO_REF:0000107
GO_REF:0000033

PMID:28469175

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

ring finger protein 135

involved_in

ISO
ISS

(PMID:28469175), (PMID:31006531)
(PMID:21147464), (PMID:23950712)
GO_REF:0000024

PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531

GO_REF:0000024

NCBI chr10:65,668,441...65,687,671
Ensembl chr10:65,170,560...65,262,804

Rpsa

ribosomal protein SA

involved_in

ISO

(PMID:38114488)

PMID:38114488

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:119,851,225...119,855,247

Senp7

SUMO specific peptidase 7

involved_in

ISS
ISO

GO_REF:0000024
(PMID:28095500)

PMID:28095500

GO_REF:0000024

NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711

Serinc3

serine incorporator 3

involved_in

IEA
ISO

GO_REF:0000107
(PMID:26416733), (PMID:26416734), (PMID:37474505)

PMID:26416733 PMID:26416734 PMID:37474505

GO_REF:0000107

NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808

Serinc5

serine incorporator 5

involved_in

ISS
ISO

GO_REF:0000024
(PMID:26416733), (PMID:26416734), (PMID:37474505)

PMID:26416733 PMID:26416734 PMID:37474505

GO_REF:0000024

NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346

Smarca5

SNF2 related chromatin remodeling ATPase 5

involved_in

ISO
IEA

(PMID:38114488)
GO_REF:0000107

PMID:38114488

GO_REF:0000107

NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594

stimulator of interferon response cGAMP interactor 1

involved_in

ISO
IEA

(PMID:21074459)
GO_REF:0000107

PMID:21074459

GO_REF:0000107

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

TANK-binding kinase 1

involved_in

ISO
IEA

(PMID:14703513), (PMID:22394562)
GO_REF:0000107

PMID:14703513 PMID:22394562

GO_REF:0000107

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

Tmem120a

transmembrane protein 120A

involved_in

ISO
IEA

(PMID:35013224)
GO_REF:0000107

PMID:35013224

GO_REF:0000107

NCBI chr12:20,942,243...20,950,908
Ensembl chr12:20,942,439...20,990,316

Tnf

tumor necrosis factor

involved_in

ISO
IEA

(PMID:11773383)
GO_REF:0000107

PMID:11773383

GO_REF:0000107

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Traf3ip3

TRAF3 interacting protein 3

acts_upstream_of_or_within

ISO

MGI:5795738 (PMID:31390091)

PMID:31390091

NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673

TNF receptor associated factor 6

involved_in

ISO

(PMID:18984593)

PMID:18984593

NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507

tripartite motif-containing 21

involved_in

ISO
IEA

(PMID:36943869)
GO_REF:0000107

PMID:36943869

GO_REF:0000107

NCBI chr 1:166,376,829...166,399,441
Ensembl chr 1:156,964,913...156,987,440

tripartite motif-containing 25

involved_in

ISO
IEA

(PMID:17392790)
GO_REF:0000107

PMID:17392790

GO_REF:0000107

NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257

tripartite motif-containing 31

involved_in

ISO
IEA

(PMID:27992402)
GO_REF:0000107

PMID:27992402

GO_REF:0000107

NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494

Trim6

tripartite motif containing 6

involved_in

ISO
IEA

(PMID:35263596)
GO_REF:0000107

PMID:35263596

GO_REF:0000107

NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914

tripartite motif-containing 65

acts_upstream_of_or_within

ISO

MGI:6356825|MGI:6356826|MGI:6356827 (PMID:28031478)

NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971

Trim7

tripartite motif-containing 7

involved_in

ISO

(PMID:35893676)

PMID:35893676

NCBI chr10:33,706,614...33,722,609
Ensembl chr10:33,205,491...33,221,468

Uap1

UDP-N-acetylglucosamine pyrophosphorylase 1

involved_in

ISO

(PMID:36603579)

PMID:36603579

NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
Ensembl chr 6:82,342,946...82,377,469

Ube2n

ubiquitin-conjugating enzyme E2N

involved_in

ISO

(PMID:35893676)

PMID:35893676

NCBI chr 7:32,041,190...32,071,252
Ensembl chr 7:30,154,616...30,184,355

Ube2w

ubiquitin-conjugating enzyme E2W

involved_in

ISO

(PMID:35893676)

PMID:35893676

NCBI chr 5:7,474,039...7,531,526
Ensembl chr 5:2,690,763...2,814,965

Ubl7

ubiquitin-like 7

involved_in

ISO
IEA

(PMID:36943869)
GO_REF:0000107

PMID:36943869

GO_REF:0000107

NCBI chr 8:58,321,279...58,340,353
Ensembl chr 8:58,320,866...58,340,344

Usp18

ubiquitin specific peptidase 18

involved_in

ISO

(PMID:27801882)

PMID:27801882

NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144

Usp20

ubiquitin specific peptidase 20

involved_in

ISO
IEA

(PMID:27801882)
GO_REF:0000107

PMID:27801882

GO_REF:0000107

NCBI chr 3:14,272,737...14,306,409
Ensembl chr 3:14,272,908...14,306,409

Usp44

ubiquitin specific peptidase 44

involved_in

ISO
IEA

(PMID:31968013)
GO_REF:0000107

PMID:31968013

GO_REF:0000107

NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:28,364,033...28,410,053

Z-DNA binding protein 1

involved_in

ISO

(PMID:34192517)

PMID:34192517

NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:161,993,351...162,003,870

Zdhhc1

zinc finger, DHHC-type containing 1

involved_in

ISO
IBA

(PMID:25299331)
GO_REF:0000033

PMID:25299331

GO_REF:0000033

NCBI chr19:50,260,445...50,285,634
Ensembl chr19:33,350,533...33,375,616

Zdhhc11

zinc finger, DHHC-type containing 11

involved_in

ISO
IBA

(PMID:29429998)
GO_REF:0000033

PMID:29429998

GO_REF:0000033

NCBI chr 1:31,124,900...31,156,075
Ensembl chr 1:29,296,334...29,326,898

biosynthetic process of antibacterial peptides active against Gram-negative bacteria

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Elane

elastase, neutrophil expressed

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

biosynthetic process of antibacterial peptides active against Gram-positive bacteria

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nucleotide-binding oligomerization domain containing 2

acts_upstream_of

ISO

MGI:3529594 (PMID:15692051)

PMID:15692051

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

cell surface pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD14 molecule

involved_in

ISO

(PMID:15294986)

PMID:15294986

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261

C-type lectin domain containing 7A

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:12719478)
GO_REF:0000107
(PMID:19358895)

PMID:12719478 PMID:19358895

GO_REF:0000107

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

Fcna

ficolin A

involved_in

ISS

GO_REF:0000024

GO_REF:0000024

NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105

ficolin B

involved_in

ISO
IEA

(PMID:21037097)
GO_REF:0000107

PMID:21037097

GO_REF:0000107

NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151

Ffar2

free fatty acid receptor 2

involved_in

ISO
IEA
ISS

(PMID:21037097)
GO_REF:0000107
GO_REF:0000024

PMID:21037097

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033

lipopolysaccharide binding protein

involved_in

ISO
IEA

(PMID:15294986)
GO_REF:0000107

PMID:15294986

GO_REF:0000107

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

mannose binding lectin 2

involved_in

ISO

(PMID:22966085)

PMID:22966085

NCBI chr 1:228,016,439...228,024,736

Syk

spleen associated tyrosine kinase

involved_in

ISO
IEA

(PMID:19358895)
GO_REF:0000107

PMID:19358895

GO_REF:0000107

NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410

toll-like receptor 2

acts_upstream_of_or_within

ISO

MGI:2178675 (PMID:12719478)

PMID:12719478

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

cellular response to type I interferon

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mx2

MX dynamin like GTPase 2

involved_in

ISO

(PMID:24500530)

PMID:24500530

NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342

Nr1i2

nuclear receptor subfamily 1, group I, member 2

involved_in

ISO

(PMID:24525126)

PMID:24525126

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

three prime repair exonuclease 1

acts_upstream_of_or_within

ISO
IEA

(PMID:28835460)
GO_REF:0000107

PMID:28835460

GO_REF:0000107

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

cellular response to type II interferon

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aconitate decarboxylase 1

involved_in

ISO

(PMID:19014335)

PMID:19014335

NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529

Actg1

actin, gamma 1

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232

Actr2

actin related protein 2

acts_upstream_of_or_within

ISO
IEA

MGI:1921367 (PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524

Actr3

actin related protein 3

acts_upstream_of_or_within

ISO
IEA

MGI:1913963 (PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124

Adamts13

ADAM metallopeptidase with thrombospondin type 1 motif, 13

IEP

RGD

PMID:18433458

RGD:2315954

NCBI chr 3:10,299,264...10,338,464
Ensembl chr 3:10,300,028...10,346,687

Aif1

allograft inflammatory factor 1

involved_in

ISO
IEP

(PMID:9614071)
PMID:7769138

PMID:9614071 PMID:7769138

RGD:61535

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

Aqp4

aquaporin 4

involved_in

ISO
IEA

(PMID:17645239)
GO_REF:0000107

PMID:12589771 PMID:11072090

PMID:17645239

GO_REF:0000107

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

Arg2

arginase 2

IEP

RGD

PMID:11250887

RGD:4144048

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

Asl

argininosuccinate lyase

IEP

with TNFalpha

RGD

PMID:11072090

RGD:4139899

NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662

Ass1

argininosuccinate synthase 1

IEP

with TNFalpha

RGD

RGD:1599307, RGD:4139899

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

Atl3

atlastin GTPase 3

involved_in

IEA

GO_REF:0000117

GO_REF:0000117

NCBI chr 1:204,680,958...204,727,360
Ensembl chr 1:204,680,968...204,723,354

Calm1

calmodulin 1

involved_in

ISO
IEA

(PMID:11972023)
GO_REF:0000107

GO_REF:0000107

NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:119,487,621...119,498,227

Calm2

calmodulin 2

involved_in

ISO

(PMID:11972023)

NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287

Calm3

calmodulin 3

involved_in

ISO

(PMID:11972023)

NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207

Camk2a

calcium/calmodulin-dependent protein kinase II alpha

involved_in

IEA
ISO

GO_REF:0000107
(PMID:11972023)

GO_REF:0000107

NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994

Capg

capping actin protein, gelsolin like

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

Casp1

caspase 1

involved_in

ISO

(PMID:11536016)

PMID:11536016

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

Ccl2

C-C motif chemokine ligand 2

involved_in

IEP
IEA
ISO

GO_REF:0000107
(PMID:14662900)
(PMID:9407497)

PMID:9407497 PMID:14662900 PMID:14512159

GO_REF:0000107, RGD:8548859

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

Ccl3

C-C motif chemokine ligand 3

involved_in

ISO

(PMID:9407497)

PMID:9407497

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

Ccl5

C-C motif chemokine ligand 5

involved_in

ISO

(PMID:9407497)

PMID:9407497

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

Cd200

Cd200 molecule

involved_in

IEA
ISO

GO_REF:0000107
(PMID:26670206)

PMID:26670206

GO_REF:0000107

NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648

Cd47

Cd47 molecule

involved_in

IMP

PMID:12023387

ARUK-UCL

PMID:12023387

RGD:625650

NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425

Cdc42

cell division cycle 42

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:149,553,724...149,593,111

Cdc42ep2

CDC42 effector protein 2

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897

Cdc42ep4

CDC42 effector protein 4

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695

Cfh

complement factor H

IEP

RGD

PMID:12121434

RGD:632369

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

class II, major histocompatibility complex, transactivator

IEP

RGD

PMID:11071855

RGD:632488

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

Cldn1

claudin 1

IEP

RGD

PMID:18768927

RGD:11344890

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

Cripto

cripto, EGF-CFC family member

involved_in

ISO

(PMID:17720976)

PMID:17720976

NCBI chr 8:119,803,182...119,808,714
Ensembl chr 8:110,925,024...110,930,308

Cyp11b1

cytochrome P450, family 11, subfamily b, polypeptide 1

IEP

RGD

PMID:12121434

RGD:632369

NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278

Dapk1

death associated protein kinase 1

involved_in

ISO
IEA

(PMID:18995835)
GO_REF:0000107
(PMID:23071094)

PMID:18995835 PMID:23071094

GO_REF:0000107

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

Dapk3

death-associated protein kinase 3

involved_in

ISO
IEA

(PMID:18995835)
(PMID:23071094)
GO_REF:0000107

PMID:18995835 PMID:23071094

GO_REF:0000107

NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558

Daxx

death-domain associated protein

IMP

RGD

PMID:21572393

RGD:9587767

NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843

Edn1

endothelin 1

IEP

RGD

PMID:22301113

RGD:8662301

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

ENSRNOG00000065742

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000117

GO_REF:0000033 GO_REF:0000117

Ensembl chr 2:231,461,798...231,474,541

ENSRNOG00000066766

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000117

GO_REF:0000033 GO_REF:0000117

Ensembl chr14:4,692,271...4,708,839

Eprs1

glutamyl-prolyl-tRNA synthetase 1

involved_in

ISO
IEA

(PMID:15479637)
GO_REF:0000107
(PMID:23071094)

PMID:15479637 PMID:23071094

GO_REF:0000107

NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966

Epsti1

epithelial stromal interaction 1

acts_upstream_of_or_within

ISO

(PMID:29217193)

PMID:29217193

NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191

Evl

Enah/Vasp-like

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344

Fas

Fas cell surface death receptor

IEP

RGD

PMID:10029626

RGD:14700709

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591

Faslg

Fas ligand

IEP

RGD

PMID:10029626

RGD:14700709

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

Fcar

Fc alpha receptor

involved_in

ISO

(PMID:25339672)

PMID:25339672

NCBI chr 1:69,626,458...69,660,558

Flnb

filamin B

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006

Gapdh

glyceraldehyde-3-phosphate dehydrogenase

involved_in

ISO

(PMID:15479637)

PMID:17266443 PMID:18025219 PMID:21151871

PMID:15479637

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

Gbp1

guanylate binding protein 1

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:17266443), (PMID:21151871)
GO_REF:0000117
(PMID:18025219)
GO_REF:0000033

RGD
UniProt
GO_Central

GO_REF:0000033 GO_REF:0000117

NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131

Gbp1-ps1

guanylate binding protein 1, pseudogene 1

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000117

GO_REF:0000033 GO_REF:0000117

NCBI chr 2:231,517,485...231,525,865
Ensembl chr 2:231,517,398...231,529,600

RGD
Ensembl
GO_Central
UniProt

guanylate binding protein 2

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:17266443)
GO_REF:0000107
(PMID:18025219)
GO_REF:0000033
GO_REF:0000117

PMID:17266443 PMID:18025219

GO_REF:0000033 GO_REF:0000107 GO_REF:0000117

NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571

Gbp3

guanylate binding protein 3

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000117

GO_REF:0000033 GO_REF:0000117

NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098

Gbp4

guanylate binding protein 4

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:17266443)
GO_REF:0000107
GO_REF:0000117
(PMID:18025219)
GO_REF:0000033

PMID:17266443 PMID:18025219

GO_REF:0000033 GO_REF:0000107 GO_REF:0000117

NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879

guanylate binding protein 5

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:17266443)
GO_REF:0000107
GO_REF:0000117
(PMID:18025219)
GO_REF:0000033

PMID:17266443 PMID:18025219

GO_REF:0000033 GO_REF:0000107 GO_REF:0000117

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

Gbp6

guanylate binding protein family member 6

involved_in
acts_upstream_of_or_within

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000117
(PMID:18025219)

GO_Central
UniProt
RGD

GO_REF:0000033 GO_REF:0000117

NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062

Gbp6-ps1

guanylate binding protein 6, pseudogene 1

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000117

GO_REF:0000033 GO_REF:0000117

NCBI chr14:4,661,784...4,678,989
Ensembl chr14:4,663,614...4,678,985

Gbp6-ps2

guanylate binding protein 6, pseudogene 2

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000117

GO_Central
Ensembl
UniProt
RGD

GO_REF:0000033 GO_REF:0000117

NCBI chr 2:231,643,579...231,672,818
Ensembl chr 2:231,643,535...231,741,152

Gbp7

guanylate binding protein 7

involved_in
acts_upstream_of_or_within

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
GO_REF:0000117
(PMID:18025219)

GO_REF:0000033 GO_REF:0000107 GO_REF:0000117

NCBI chr 2:231,275,521...231,297,289
Ensembl chr 2:231,275,640...231,297,278

Gsn

gelsolin

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402

Icam1

intercellular adhesion molecule 1

IEP

RGD

PMID:7865494

RGD:11520781

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

Il12b

interleukin 12B

acts_upstream_of_or_within

ISO

(PMID:18025219)

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

Il12rb1

interleukin 12 receptor subunit beta 1

involved_in

ISO

(PMID:12023369)

PMID:12023369

NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769

Il18

interleukin 18

IEP

RGD

PMID:18547159

RGD:4889457

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

interferon regulatory factor 1

IEP

RGD

PMID:21261980

RGD:5128727

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166

Irf8

interferon regulatory factor 8

involved_in

ISO
IEA
IEP

(PMID:25122610)
GO_REF:0000107

PMID:25122610 PMID:21261980

GO_REF:0000107, RGD:5128727

NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829

immunity-related GTPase M

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

Kif16b

kinesin family member 16B

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019

Kif5b

kinesin family member 5B

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508

galectin 9

involved_in

ISO

(PMID:23817958)

PMID:23817958

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

Mrc1

mannose receptor, C type 1

acts_upstream_of_or_within

ISO
IEA

(PMID:22832163)
GO_REF:0000107

PMID:22832163

GO_REF:0000107

NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857

Mst1

macrophage stimulating 1

IEP

RGD

PMID:21572393

RGD:9587767

NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416

Myc

MYC proto-oncogene, bHLH transcription factor

IEP

RGD

PMID:7524476

RGD:10059620

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630

Myo18a

myosin XVIIIa

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468

Myo1c

myosin 1C

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752

Nos2

nitric oxide synthase 2

acts_upstream_of_or_within

ISO

(PMID:18025219)

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

Pde12

phosphodiesterase 12

involved_in

IEA
ISO

GO_REF:0000107
(PMID:15231837)

PMID:15231837

GO_REF:0000107

NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887

Pecam1

platelet and endothelial cell adhesion molecule 1

IEP

RGD

PMID:18466611

RGD:2311658

NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116

Pim1

Pim-1 proto-oncogene, serine/threonine kinase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:37797010)

PMID:37797010

GO_REF:0000024 GO_REF:0000107

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

Rab11fip5

RAB11 family interacting protein 5

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741

Rab12

RAB12, member RAS oncogene family

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910

Rab20

RAB20, member RAS oncogene family

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529

Rab43

RAB43, member RAS oncogene family

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 4:120,249,650...120,269,174
Ensembl chr 4:120,249,879...120,269,174

Rab7b

Rab7b, member RAS oncogene family

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581

Rpl13a

ribosomal protein L13A

involved_in

ISO
IEA

(PMID:15479637)
GO_REF:0000107
(PMID:23071094)

PMID:15479637 PMID:23071094

GO_REF:0000107

NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463

Rps6kb1

ribosomal protein S6 kinase B1

involved_in

ISO

(PMID:28178239)

PMID:28178239

NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908

RT1-Bb

RT1 class II, locus Bb

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597

RT1-Ha

RT1 class II, locus Ha

involved_in

ISO
IEA

(PMID:8568247)
GO_REF:0000107

PMID:8568247

GO_REF:0000107

NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244

Serpina3n

serpin family A member 3N

IEP

RGD

PMID:7619083

RGD:5147424

NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433

Sirpa

signal-regulatory protein alpha

involved_in

IMP

PMID:12023387

ARUK-UCL

PMID:12023387

RGD:625650

NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098

Slc26a6

solute carrier family 26 member 6

involved_in

ISO
IEA

(PMID:18655181)
GO_REF:0000107

PMID:18655181

GO_REF:0000107

NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778

Slk

STE20-like kinase

IDA

RGD

PMID:21572393

RGD:9587767

NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530

Socs1

suppressor of cytokine signaling 1

IEP

RGD

PMID:10707961

RGD:151232287

NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383

Socs3

suppressor of cytokine signaling 3

IEP

RGD

PMID:10707961

RGD:151232287

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

Star

steroidogenic acute regulatory protein

IEP

RGD

PMID:9564825

RGD:4891971

NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672

signal transducer and activator of transcription 1

involved_in

ISO

(PMID:11972023), (PMID:23386060)

PMID:11972023 PMID:23386060

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

Stx11

syntaxin 11

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164

Stx4

syntaxin 4

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979

Stx8

syntaxin 8

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993

Stxbp1

syntaxin binding protein 1

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369

Stxbp2

syntaxin binding protein 2

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458

Stxbp3

syntaxin binding protein 3

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671

Stxbp4

syntaxin binding protein 4

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663

Syncrip

synaptotagmin binding, cytoplasmic RNA interacting protein

involved_in

ISO

(PMID:15479637)

PMID:15479637

NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515

toll-like receptor 2

involved_in

ISO

(PMID:11672593)

PMID:11672593

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

PMID:16638093 PMID:15661832

toll-like receptor 3

NOT

IEP

intestinal epithelial cells
thyrocytes

RGD

RGD:5128794, RGD:5128798

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

toll-like receptor 4

involved_in

ISO
IEA

(PMID:11672593)
GO_REF:0000107

PMID:11672593

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tnf

tumor necrosis factor

involved_in

IEP
ISO

(PMID:29849090)

PMID:29849090 PMID:16525716

RGD:14985246

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Vamp3

vesicle-associated membrane protein 3

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 5:166,780,927...166,791,522
Ensembl chr 5:161,498,109...161,508,751

Vamp4

vesicle-associated membrane protein 4

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr13:74,919,872...74,942,791
Ensembl chr13:74,919,880...74,933,686

Vamp8

vesicle-associated membrane protein 8

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897

Vim

vimentin

acts_upstream_of_or_within

ISO

(PMID:19144319)

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187

Vps26b

VPS26 retromer complex component B

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr 8:25,415,877...25,436,985
Ensembl chr 8:25,415,261...25,436,985

Was

WASP actin nucleation promoting factor

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr X:14,405,105...14,413,850
Ensembl chr X:14,405,124...14,413,849

Wnt5a

Wnt family member 5A

involved_in

ISO
IEA

(PMID:18174455)
GO_REF:0000107

PMID:18174455

GO_REF:0000107

NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234

Zyx

zyxin

acts_upstream_of_or_within

ISO
IEA

(PMID:19144319)
GO_REF:0000107

GO_REF:0000107

NCBI chr 4:71,236,767...71,246,553
Ensembl chr 4:71,237,451...71,246,553

cGAS/STING signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cyclic GMP-AMP synthase

involved_in

ISO
IEA

(PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603), (PMID:39322678)
GO_REF:0000107
(PMID:39322678)

PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More...

GO_REF:0000107

NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496

Ddx41

DEAD-box helicase 41

involved_in

ISO

(PMID:35613581)

PMID:35613581

NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415

stimulator of interferon response cGAMP interactor 1

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:37832545)
(PMID:25636800), (PMID:30842659), (PMID:30842662), (PMID:35388221), (PMID:37832545)
GO_REF:0000024

PMID:25636800 PMID:30842659 PMID:30842662 PMID:35388221 PMID:37832545

GO_REF:0000024 GO_REF:0000107

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

clearance of foreign intracellular DNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apobec3

apolipoprotein B mRNA editing enzyme catalytic subunit 3

involved_in

ISO

(PMID:20062055)

PMID:20062055

NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922

complement activation, alternative pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement C3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

complement C5

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

C5l1

complement C5 like 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054

C8a

complement C8 alpha chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

C8b

complement C8 beta chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

complement C9

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

Cfb

complement factor B

acts_upstream_of_or_within
involved_in

ISO
IEA

MGI:1861129 (PMID:27564415), (PMID:9238044)
GO_REF:0000043

PMID:9238044 PMID:27564415

GO_REF:0000043

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

Cfd

complement factor D

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:27564415)
GO_REF:0000107
GO_REF:0000043

PMID:27564415

GO_REF:0000043 GO_REF:0000107

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

Cfh

complement factor H

acts_upstream_of_or_within
acts_upstream_of_or_within_negative_effect

ISO

(PMID:27564415)
(PMID:19828624)

PMID:19828624 PMID:27564415

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

Cfp

complement factor properdin

involved_in

ISO
IEA

MGI:3774548 (PMID:18292556)
GO_REF:0000107

PMID:18292556

GO_REF:0000107

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

Cr2

complement C3d receptor 2

involved_in
acts_upstream_of_or_within_negative_effect

ISO

(PMID:11981823)
(PMID:19828624)

PMID:11981823 PMID:19828624

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

complement activation, lectin pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07006691.1

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000043
GO_REF:0000107

UniProt
Ensembl

GO_REF:0000043 GO_REF:0000107

Ensembl chr 1:228,016,498...228,043,066

Cd69

Cd69 molecule

TAS

RGD

PMID:11034393 PMID:15506986

RGD:1354527, RGD:1354528

NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542

Colec10

collectin subfamily member 10

involved_in

ISO
IEA

(PMID:24174618)
GO_REF:0000107

PMID:24174618

GO_REF:0000107

NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675

Colec11

collectin sub-family member 11

involved_in

ISO

(PMID:24174618), (PMID:25912189)

PMID:24174618 PMID:25912189

NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145

Fcna

ficolin A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105

RGD
UniProt
Ensembl
GO_Central

ficolin B

involved_in

ISO
IEA
IBA

(PMID:16116205)
GO_REF:0000043
GO_REF:0000107
GO_REF:0000033

PMID:16116205

GO_REF:0000033 GO_REF:0000043 GO_REF:0000107

NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151

Krt1

keratin 1

involved_in

ISO
IEA

UniProtKB:P11226 (PMID:11549596)
GO_REF:0000107

UniProt
RGD
GO_Central
Ensembl

PMID:11549596

GO_REF:0000107

NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844

Masp1

MBL associated serine protease 1

involved_in

ISS
IEA
ISO
IBA

GO_REF:0000024
GO_REF:0000043
(PMID:18424734)
GO_REF:0000033
GO_REF:0000107
(PMID:17182967)

PMID:17182967 PMID:18424734

GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

Masp2

MBL associated serine protease 2

involved_in

ISO
IBA
IEA

(PMID:17182967), (PMID:9087411)
GO_REF:0000033
GO_REF:0000107

PMID:9087411 PMID:17182967

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

Mbl1

mannose binding lectin 1

involved_in
acts_upstream_of_or_within

IDA
IEA
ISO

GO_REF:0000043
MGI:96924 (PMID:15148336)

PMID:15148336 PMID:16272342

GO_REF:0000043, RGD:1582134

NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174

mannose binding lectin 2

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:15148336)
GO_REF:0000107
GO_REF:0000043
MGI:3577339|MGI:96923 (PMID:15148336)
UniProtKB:P04264 (PMID:11549596), (PMID:22691502), (PMID:35102342)

PMID:11549596 PMID:15148336 PMID:22691502 PMID:35102342

GO_REF:0000043 GO_REF:0000107

NCBI chr 1:228,016,439...228,024,736

cytolysis by host of symbiont cells

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cathelicidin antimicrobial peptide

involved_in

ISO

(PMID:20421939)

PMID:20421939

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

Cfhr1

complement factor H-related 1

involved_in

ISO

(PMID:23487775)

PMID:23487775

NCBI chr13:51,395,583...51,410,571
Ensembl chr13:51,369,211...51,410,592

coagulation factor II, thrombin

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

Romo1

reactive oxygen species modulator 1

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 3:144,659,709...144,661,310
Ensembl chr 3:144,659,826...144,661,310

cytoplasmic pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alpk1

alpha-kinase 1

involved_in

ISO
IBA

(PMID:28222186), (PMID:28877472), (PMID:30111836)
(PMID:30111836)
GO_REF:0000033

PMID:28222186 PMID:28877472 PMID:30111836

GO_REF:0000033

NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157

Becn1

beclin 1

involved_in

ISO
IEA

(PMID:34796041)
GO_REF:0000107

PMID:34796041

GO_REF:0000107

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

cyclic GMP-AMP synthase

involved_in

ISO
IEA

(PMID:23258413)
GO_REF:0000107

PMID:23258413

GO_REF:0000107

NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496

DEAD-box helicase 3, X-linked

involved_in

ISO

(PMID:23478265)

PMID:23478265

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

DEXH-box helicase 58

involved_in

ISO
IEA
IBA

(PMID:19211564)
GO_REF:0000107
GO_REF:0000033

PMID:19211564

GO_REF:0000033 GO_REF:0000107

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Ipo5

importin 5

involved_in

ISO

(PMID:31340999)

PMID:31340999

NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126

interferon regulatory factor 3

involved_in

ISO
IEA

(PMID:8524823)
GO_REF:0000107

PMID:8524823

GO_REF:0000107

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

interferon regulatory factor 7

involved_in

ISO
IEA

(PMID:21931555)
GO_REF:0000107

PMID:21931555

GO_REF:0000107

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

mitochondrial antiviral signaling protein

involved_in

ISO

(PMID:16125763), (PMID:20451243)

PMID:16125763 PMID:20451243

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

RNA sensor RIG-1

involved_in

ISO
IEA
IBA

(PMID:19576794)
GO_REF:0000107
GO_REF:0000033

PMID:19576794

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

stimulator of interferon response cGAMP interactor 1

involved_in

ISO
IEA

(PMID:23910378), (PMID:35388221)
GO_REF:0000107

PMID:23910378 PMID:35388221

GO_REF:0000107

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

TANK-binding kinase 1

involved_in

ISO
IEA

(PMID:29441066)
GO_REF:0000107

PMID:29441066

GO_REF:0000107

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

Tifa

TRAF-interacting protein with forkhead-associated domain

involved_in

ISO
IBA
ISS

(PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)
GO_REF:0000033
GO_REF:0000024

PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836

GO_REF:0000024 GO_REF:0000033

NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841

Traf3ip3

TRAF3 interacting protein 3

involved_in

ISO
IEA
IBA

(PMID:31390091)
GO_REF:0000107
GO_REF:0000033

PMID:31390091

GO_REF:0000033 GO_REF:0000107

NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673

TNF receptor associated factor 6

involved_in

ISO

(PMID:20501938), (PMID:23015697)

PMID:20501938 PMID:23015697

NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507

tripartite motif-containing 25

involved_in

ISO
IEA

(PMID:17392790)
GO_REF:0000107

PMID:17392790

GO_REF:0000107

NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257

Ywhae

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

involved_in

ISO

(PMID:22607805)

PMID:22607805

NCBI chr10:61,082,934...61,120,618
Ensembl chr10:60,584,652...60,671,589

endolysosomal toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Washc4

WASH complex subunit 4

acts_upstream_of_or_within

ISO

(PMID:33749590)

PMID:33749590

NCBI chr 7:20,187,905...20,240,228
Ensembl chr 7:20,187,922...20,240,226

host-mediated suppression of symbiont invasion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apcs

amyloid P component, serum

involved_in

IEA
ISO

GO_REF:0000107
(PMID:23544079)

GO_REF:0000107

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

Cd74

CD74 molecule

involved_in

ISO

(PMID:32855215)

PMID:32855215

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

class II, major histocompatibility complex, transactivator

involved_in

ISO

(PMID:32855215)

PMID:32855215

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

ENSRNOG00000068074

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 4:59,549,152...59,549,829

ENSRNOG00000070481

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 4:30,960,845...30,961,834

ficolin B

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151

Gsn

gelsolin

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402

Ifitm1

interferon induced transmembrane protein 1

involved_in
acts_upstream_of_or_within

ISO
IBA

(PMID:21253575), (PMID:23358889), (PMID:26354436)
(PMID:25738301)
GO_REF:0000033

PMID:21253575 PMID:23358889 PMID:25738301 PMID:26354436

GO_REF:0000033

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

Ifitm2

interferon induced transmembrane protein 2

involved_in

ISO
IBA

(PMID:21253575), (PMID:23358889), (PMID:26354436), (PMID:33563656)
GO_REF:0000033

PMID:21253575 PMID:23358889 PMID:26354436 PMID:33563656

GO_REF:0000033

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

Ifitm2-ps2

interferon induced transmembrane protein 2, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:68,187,131...68,187,808
Ensembl chr13:68,187,366...68,187,854

Ifitm3

interferon induced transmembrane protein 3

involved_in

ISS
ISO
IBA

GO_REF:0000024
(PMID:21253575)
GO_REF:0000033
(PMID:20943977), (PMID:21253575), (PMID:23358889), (PMID:26354436)

PMID:20943977 PMID:21253575 PMID:23358889 PMID:26354436

GO_REF:0000024 GO_REF:0000033

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

Ifitm3-ps1

interferon induced transmembrane protein 3, pseudogene 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr14:61,233,269...61,233,688
Ensembl chr14:61,233,269...61,233,688

Ifitm3-ps2

interferon induced transmembrane protein 3, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr11:33,137,146...33,137,562
Ensembl chr11:33,137,146...33,138,061

Ifitm6

interferon induced transmembrane protein 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:196,117,043...196,118,315
Ensembl chr 1:196,117,049...196,118,386

Lrrc15

leucine rich repeat containing 15

involved_in

ISO
IEA

(PMID:36228039), (PMID:36757924)
GO_REF:0000107

PMID:36228039 PMID:36757924

GO_REF:0000107

NCBI chr11:70,469,817...70,484,268
Ensembl chr11:70,469,804...70,484,267

Ly6e

lymphocyte antigen 6 family member E

involved_in

ISO
IEA

(PMID:32641482), (PMID:32704094)
GO_REF:0000107
(PMID:32704094)

PMID:32641482 PMID:32704094

GO_REF:0000107

NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689

Mid2

midline 2

involved_in

ISO
IEA

(PMID:18248090)
GO_REF:0000107

GO_REF:0000107

NCBI chr X:104,354,692...104,456,757
Ensembl chr X:104,355,316...104,453,473

Mre11

MRE11 homolog, double strand break repair nuclease

IMP

RGD

PMID:22850678

RGD:8693392

NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279

Nbn

nibrin

IMP

RGD

PMID:22850678

RGD:8693392

NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:29,459,457...29,494,150

Ptx3

pentraxin 3

involved_in

ISO

(PMID:23544079)

NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323

Rad50

RAD50 double strand break repair protein

IMP

RGD

PMID:22850678

RGD:8693392

NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396

Snx3

sorting nexin 3

involved_in

ISO

(PMID:18767904)

PMID:18767904

NCBI chr20:45,992,446...46,025,361
Ensembl chr20:45,992,720...46,025,379

Tmeff1

transmembrane protein with EGF-like and two follistatin-like domains 1

involved_in

ISO
IEA
ISS

(PMID:39048823), (PMID:39048830)
GO_REF:0000107
GO_REF:0000024

PMID:39048823 PMID:39048830

GO_REF:0000024 GO_REF:0000107

NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493

Trim10

tripartite motif-containing 10

involved_in

ISO
IEA

(PMID:18248090)
GO_REF:0000107

GO_REF:0000107

NCBI chr20:1,694,771...1,703,724
Ensembl chr20:1,689,562...1,698,252

Trim11

tripartite motif-containing 11

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr10:44,255,019...44,270,711
Ensembl chr10:43,758,354...43,771,138

tripartite motif-containing 25

involved_in

ISO
IEA

(PMID:18248090)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257

Trim26

tripartite motif-containing 26

involved_in

ISO
IBA
IEA

(PMID:18248090)
GO_REF:0000033
GO_REF:0000107

GO_REF:0000033 GO_REF:0000107

NCBI chr20:1,711,564...1,736,389
Ensembl chr20:1,709,788...1,731,120

tripartite motif-containing 31

involved_in

ISO
IEA

(PMID:18248090)
GO_REF:0000107

GO_REF:0000107

NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494

Trim5

tripartite motif-containing 5

involved_in

ISO

(PMID:18248090)

NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:158,720,410...158,814,012

tripartite motif containing 56

involved_in

ISO

(PMID:18248090)

NCBI chr12:25,193,224...25,204,032
Ensembl chr12:19,551,521...19,567,462

Trim59

tripartite motif-containing 59

involved_in

ISO
IEA

(PMID:18248090)
GO_REF:0000107

GO_REF:0000107

NCBI chr 2:155,579,183...155,593,450
Ensembl chr 2:153,268,584...153,281,031

Trim8

tripartite motif-containing 8

involved_in

ISO

(PMID:18248090)

NCBI chr 1:255,311,039...255,325,937
Ensembl chr 1:245,369,632...245,384,513

induced systemic resistance

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MYD88, innate immune signal transduction adaptor

acts_upstream_of_or_within

ISO
IEA

MGI:4421295 (PMID:25084278)
GO_REF:0000107

PMID:25084278

GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

induction of bacterial agglutination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fga

fibrinogen alpha chain

involved_in

ISO

(PMID:24367264)

PMID:24367264

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

Fgb

fibrinogen beta chain

involved_in

ISO
IEA

(PMID:24367264)
GO_REF:0000107

PMID:24367264

GO_REF:0000107

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

Rnase2

ribonuclease A family member 2

NOT|involved_in

ISO

(PMID:23992292)

PMID:23992292

NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479

Spon2

spondin 2

acts_upstream_of_or_within

ISO
IEA

(PMID:14691481)
GO_REF:0000107

PMID:14691481

GO_REF:0000107

NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996

inflammasome-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Elp6

elongator acetyltransferase complex subunit 6

acts_upstream_of_or_within

ISO

(PMID:30097576)

PMID:30097576

NCBI chr 8:110,280,059...110,295,070
Ensembl chr 8:110,279,979...110,295,067

innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07006691.1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr 1:228,016,498...228,043,066

AABR07035218.1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr12:5,901,586...5,978,565

AC108595.1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr 7:122,951,378...122,953,062

Adam15

ADAM metallopeptidase domain 15

involved_in

ISO
IEA
IBA

(PMID:22505472)
GO_REF:0000107
GO_REF:0000033

PMID:22505472

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113

Adar

adenosine deaminase, RNA-specific

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282

Adgrb1

adhesion G protein-coupled receptor B1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902

Akap8

A-kinase anchoring protein 8

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 7:11,316,224...11,332,523
Ensembl chr 7:11,316,228...11,332,399

Akirin2

akirin 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568

Alpk1

alpha-kinase 1

involved_in

ISO
IBA

(PMID:28222186), (PMID:28877472), (PMID:30111836)
(PMID:30111836)
GO_REF:0000033

PMID:28222186 PMID:28877472 PMID:30111836

GO_REF:0000033

NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157

angiogenin

involved_in

ISO

(PMID:12548285)

NCBI chr15:24,312,711...24,323,361

Ang2

angiogenin, ribonuclease A family, member 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,398,330...24,415,909
Ensembl chr15:24,398,419...24,398,922

Ankhd1

ankyrin repeat and KH domain containing 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024

Ankrd17

ankyrin repeat domain 17

involved_in

ISO
IEA
IBA

(PMID:23711367)
GO_REF:0000107
GO_REF:0000033

PMID:23711367

GO_REF:0000033 GO_REF:0000107

NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617

Anks6

ankyrin repeat and sterile alpha motif domain containing 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596

Anxa1

annexin A1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

Apcs

amyloid P component, serum

involved_in

ISO
IEA
IBA

(PMID:23544079)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

Apobec3

apolipoprotein B mRNA editing enzyme catalytic subunit 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922

amyloid beta precursor protein

involved_in

IDA
ISO

PMID:20209079
(PMID:20209079)

PMID:20209079 PMID:20209079

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

Arg1

arginase 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

Arg2

arginase 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

Arhgef2

Rho/Rac guanine nucleotide exchange factor 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:174,062,976...174,118,355

Atg12

autophagy related 12

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr18:41,638,841...41,649,311
Ensembl chr18:39,452,191...39,462,418

Atg14

autophagy related 14

acts_upstream_of_or_within

ISO
IEA

(PMID:26764600)
GO_REF:0000107

GO_REF:0000107

NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113

Atg5

autophagy related 5

acts_upstream_of_or_within

ISO
IEA

(PMID:26764600)
GO_REF:0000107

GO_REF:0000107

NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209

Atg7

autophagy related 7

acts_upstream_of_or_within

ISO

(PMID:26764600)

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

Atg9a

autophagy related 9A

acts_upstream_of_or_within

ISO

MGI:4417824 (PMID:19926846)

PMID:19926846

NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986

Atp1b1

ATPase Na+/K+ transporting subunit beta 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459

B2m

beta-2 microglobulin

involved_in

ISO

(PMID:23144825)

PMID:23144825

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766

Bcl10

BCL10, immune signaling adaptor

involved_in

ISO
IEA
ISS

(PMID:16831874)
GO_REF:0000107
GO_REF:0000043
GO_REF:0000024

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

Bpi

bactericidal/permeability-increasing protein

involved_in

IEA
IBA

GO_REF:0000104
GO_REF:0000043
GO_REF:0000033

UniProt
GO_Central

GO_REF:0000033 GO_REF:0000043 GO_REF:0000104

NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221

Bpifa1

BPI fold containing family A, member 1

involved_in

ISS
IEA
ISO
IBA

GO_REF:0000024
GO_REF:0000043
(PMID:23499554)
GO_REF:0000033

PMID:23499554

GO_REF:0000024 GO_REF:0000033 GO_REF:0000043

NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552

Bpifa5

BPI fold containing family A, member 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883

Bpifb1

BPI fold containing family B, member 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256

Bpifc

BPI fold containing family C

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr 7:17,848,787...17,905,993
Ensembl chr 7:17,861,007...17,905,919

Bspry

B-box and SPRY domain containing

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:80,942,974...80,965,157
Ensembl chr 5:75,927,405...75,949,583

Bst2

bone marrow stromal cell antigen 2

involved_in

ISS
IEA
ISO
IBA

GO_REF:0000024
GO_REF:0000043
(PMID:21919738)
GO_REF:0000033
(PMID:19036818)

PMID:19036818 PMID:21919738

GO_REF:0000024 GO_REF:0000033 GO_REF:0000043

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

C1qa

complement C1q A chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

C1qb

complement C1q B chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

C1qbp

complement C1q binding protein

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:56,198,534...56,203,185
Ensembl chr10:55,699,954...55,704,649

C1qc

complement C1q C chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

C1r

complement C1r

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

C1rl

complement C1r subcomponent like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:157,394,183...157,410,771
Ensembl chr 4:157,394,200...157,410,134

C1s

complement C1s

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

complement C2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

complement C3

involved_in

ISO
IEA

(PMID:16034134)
GO_REF:0000043

PMID:16034134

GO_REF:0000043

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

C4a

complement C4A

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080

C4b

complement C4B

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681

C4bpa

complement component 4 binding protein, alpha

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205

C4bpb

complement component 4 binding protein, beta

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

complement C5

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

C5l1

complement C5 like 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054

complement C6

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

C8a

complement C8 alpha chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

C8b

complement C8 beta chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

complement C9

involved_in

ISO
IEA

(PMID:16034134)
GO_REF:0000043

PMID:16034134

GO_REF:0000043

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

Calca

calcitonin-related polypeptide alpha

involved_in

ISO

(PMID:18603306)

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

cathelicidin antimicrobial peptide

involved_in

ISO
IEA
IBA

(PMID:7529412)
GO_REF:0000107
(PMID:17012259)
GO_REF:0000033
(PMID:12759353), (PMID:14978112), (PMID:17012259), (PMID:20209079), (PMID:9182550)

PMID:7529412 PMID:9182550 PMID:12759353 PMID:14978112 PMID:17012259 More...

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

Card9

caspase recruitment domain family, member 9

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237

CD14 molecule

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261

Cd180

CD180 molecule

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936

Cd1d1

CD1d1 molecule

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089

Cd55

CD55 molecule (Cromer blood group)

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

Cd59b

CD59b molecule

involved_in

ISO

(PMID:16034134)

PMID:16034134

NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847

Cfb

complement factor B

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

Cfd

complement factor D

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

Cfi

complement factor I

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561

Chid1

chitinase domain containing 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:196,594,357...196,629,700
Ensembl chr 1:196,587,509...196,629,606

Clec4a

C-type lectin domain family 4, member A

involved_in

ISO
IEA

(PMID:17050534)
GO_REF:0000043

PMID:17050534

GO_REF:0000043

NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402

Clec4d

C-type lectin domain family 4, member D

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:23602766)
GO_REF:0000043

PMID:23602766

GO_REF:0000043

NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848

Clec4e

C-type lectin domain family 4, member E

involved_in
acts_upstream_of_or_within

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000043
GO_REF:0000107
(PMID:20008526)
MGI:5013826 (PMID:23602766)

PMID:20008526 PMID:23602766

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767

Clec5a

C-type lectin domain containing 5A

involved_in

ISO
IEA
IBA

(PMID:18496526)
GO_REF:0000107
(PMID:19074552)
GO_REF:0000033

PMID:18496526 PMID:19074552

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:69,407,125...69,416,872
Ensembl chr 4:69,407,835...69,416,859

Clec6a-ps1

C-type lectin domain family 6, member A, pseudogene 1

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 4:156,539,408...156,559,032
Ensembl chr 4:156,539,408...156,558,605
Ensembl chr 4:156,539,408...156,558,605

C-type lectin domain containing 7A

involved_in

IBA
ISO

GO_REF:0000033
(PMID:15845454)

PMID:15845454

GO_REF:0000033

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

Cnpy3

canopy FGF signaling regulator 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:14,233,478...14,247,847
Ensembl chr 9:14,233,428...14,247,831

Colec11

collectin sub-family member 11

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145

Cr1l

complement C3b/C4b receptor 1 like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

Crcp

CGRP receptor component

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225

Crp

C-reactive protein

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

Csf1

colony stimulating factor 1

involved_in

IEA

GO_REF:0000043
GO_REF:0000104

GO_REF:0000043 GO_REF:0000104

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

Csf1r

colony stimulating factor 1 receptor

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

Cx3cr1

C-X3-C motif chemokine receptor 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

Cyba

cytochrome b-245 alpha chain

involved_in

ISO
IEA
ISS

(PMID:2243141)
(PMID:28351984)
GO_REF:0000107
GO_REF:0000024

PMID:2243141 PMID:28351984

GO_REF:0000024 GO_REF:0000107

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

Cybb

cytochrome b-245 beta chain

involved_in

ISO
IEA

(PMID:9774399)
GO_REF:0000107
(PMID:28351984)

PMID:9774399 PMID:28351984

GO_REF:0000107

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

Cybc1

cytochrome b-245 chaperone 1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
GO_REF:0000043
(PMID:28351984)
(PMID:30361506)

PMID:28351984 PMID:30361506

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr10:106,498,730...106,505,549
Ensembl chr10:106,498,725...106,505,596

Cyld

CYLD lysine 63 deubiquitinase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
GO_REF:0000043
(PMID:26997266)

PMID:26997266

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr19:34,487,491...34,547,311
Ensembl chr19:18,314,019...18,373,658

Cyld-ps1

CYLD lysine 63 deubiquitinase, pseudogene 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:15,202,074...15,205,290
Ensembl chr 5:15,202,251...15,205,291

Dapk1

death associated protein kinase 1

involved_in

IEA

GO_REF:0000117

GO_REF:0000117

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

Ddx1

DEAD-box helicase 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365

Ddx21

DExD-box helicase 21

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543

DEAD-box helicase 3, X-linked

involved_in

ISO

(PMID:18583960)

PMID:18583960

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

defensin alpha 5

involved_in

ISO

(PMID:21861459)

PMID:21861459

NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836

Defb1

defensin beta 1

involved_in

ISO
IEA

(PMID:12010999)
GO_REF:0000107

PMID:12010999

GO_REF:0000107

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

Defb105a

defensin beta 105A

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr16:70,136,218...70,138,645
Ensembl chr16:70,725,701...70,728,143
Ensembl chr16:70,725,701...70,728,143

Defb105b

defensin beta 105B

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr16:70,725,687...70,728,859
Ensembl chr16:70,725,701...70,728,143
Ensembl chr16:70,725,701...70,728,143

Defb13

defensin beta 13

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr16:70,129,400...70,131,509
Ensembl chr16:70,129,625...70,131,473

Defb15

defensin beta 15

involved_in

ISO
IEA

(PMID:24189797)
GO_REF:0000002

PMID:24189797

GO_REF:0000002

NCBI chr16:70,141,193...70,143,891
Ensembl chr16:70,141,193...70,143,834

Defb17

defensin beta 17

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 9:20,880,246...20,883,875

Defb18

defensin beta 18

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 9:20,852,230...20,853,247
Ensembl chr 9:20,852,300...20,853,211

Defb19

defensin beta 19

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:141,030,332...141,037,979
Ensembl chr 3:141,030,377...141,037,888

Defb20

defensin beta 20

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:140,948,108...140,950,907
Ensembl chr 3:140,948,154...140,950,777

Defb21

defensin beta 21

involved_in

ISO
IEA

(PMID:33224970)
GO_REF:0000002

PMID:33224970

GO_REF:0000002

NCBI chr 3:141,042,810...141,044,228
Ensembl chr 3:141,042,810...141,044,184

Defb22

defensin beta 22

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:140,957,093...140,961,373
Ensembl chr 3:140,957,090...140,961,373

Defb23

defensin beta 23

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:140,923,474...140,927,715
Ensembl chr 3:140,923,474...140,927,686

Defb24

defensin beta 24

involved_in

ISO
IEA

(PMID:24449502)
GO_REF:0000002

PMID:24449502

GO_REF:0000002

NCBI chr 3:141,046,571...141,052,706
Ensembl chr 3:141,046,564...141,052,753

Defb25

defensin beta 25

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:141,098,813...141,099,752
Ensembl chr 3:141,098,856...141,099,696

Defb26

defensin beta 26

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:140,977,214...140,980,949
Ensembl chr 3:140,977,489...140,980,893

Defb27

defensin beta 27

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:141,065,135...141,068,767
Ensembl chr 3:141,065,135...141,068,767

Defb28

defensin beta 28

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:140,988,032...140,993,767
Ensembl chr 3:140,988,032...140,991,015

Defb29

defensin beta 29

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:141,004,098...141,009,379
Ensembl chr 3:141,004,098...141,005,557

Defb30

defensin beta 30

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr15:37,294,713...37,298,474
Ensembl chr15:37,296,602...37,298,479

Defb34

defensin beta 34

involved_in

ISO
IEA

(PMID:24189797)
GO_REF:0000002

PMID:24189797

GO_REF:0000002

NCBI chr16:70,720,200...70,723,134
Ensembl chr16:70,720,500...70,723,098

Defb36

defensin beta 36

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:141,078,001...141,086,832
Ensembl chr 3:141,086,058...141,086,728

Defb43

defensin beta 43

involved_in

IEA
ISO

GO_REF:0000002
(PMID:26649771)

InterPro
RGD

PMID:26649771

GO_REF:0000002

NCBI chr15:37,271,888...37,276,782
Ensembl chr15:37,272,008...37,276,626

Defb49

defensin beta 49

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 9:20,832,686...20,837,352
Ensembl chr 9:20,832,686...20,837,352

Dhx36

DEAH-box helicase 36

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572

DEXH-box helicase 58

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Ecsit

ECSIT signaling integrator

involved_in

IEA
IBA

GO_REF:0000043
GO_REF:0000033

UniProt
GO_Central

GO_REF:0000033 GO_REF:0000043

NCBI chr 8:20,605,583...20,618,453
Ensembl chr 8:20,605,583...20,618,390

Eif2ak2

eukaryotic translation initiation factor 2-alpha kinase 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

Eif4ebp3

eukaryotic translation initiation factor 4E binding protein 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024

ENSRNOG00000063632

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr10:100,935,824...100,936,291

ENSRNOG00000065742

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr 2:231,461,798...231,474,541

ENSRNOG00000066766

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr14:4,692,271...4,708,839

ENSRNOG00000067088

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr18:78,340,741...78,341,528

Epg5

ectopic P-granules 5 autophagy tethering factor

acts_upstream_of_or_within

ISO
IEA

(PMID:26764600)
GO_REF:0000107

GO_REF:0000107

NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502

F2R like trypsin receptor 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

Fadd

Fas associated via death domain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

Fbxo9

f-box protein 9

acts_upstream_of_or_within

ISO

(PMID:19805818)

PMID:19805818

NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949

Fcer1g

Fc epsilon receptor Ig

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

GO_REF:0000043
MGI:2384004 (PMID:23602766)
GO_REF:0000033

PMID:23602766

GO_REF:0000033 GO_REF:0000043

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

Fcna

ficolin A

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105

ficolin B

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151

Fga

fibrinogen alpha chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

Fgb

fibrinogen beta chain

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

Fgr

FGR proto-oncogene, Src family tyrosine kinase

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

Fosl2

FOS like 2, AP-1 transcription factor subunit

acts_upstream_of_or_within

ISO
IEA

(PMID:30181393)
GO_REF:0000107

PMID:30181393

GO_REF:0000107

NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034

Gapdh

glyceraldehyde-3-phosphate dehydrogenase

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

Garin5a

golgi associated RAB2 interactor 5A

involved_in

ISO

(PMID:28930687)

PMID:28930687

NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539

Gbp1

guanylate binding protein 1

involved_in

ISO
IEA

(PMID:29144452)
GO_REF:0000043

PMID:29144452

GO_REF:0000043

NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131

Gbp1-ps1

guanylate binding protein 1, pseudogene 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:231,517,485...231,525,865
Ensembl chr 2:231,517,398...231,529,600

guanylate binding protein 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571

Gbp3

guanylate binding protein 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098

Gbp4

guanylate binding protein 4

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879

guanylate binding protein 5

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

Gbp6

guanylate binding protein family member 6

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062

Gbp6-ps1

guanylate binding protein 6, pseudogene 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr14:4,661,784...4,678,989
Ensembl chr14:4,663,614...4,678,985

Gbp6-ps2

guanylate binding protein 6, pseudogene 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:231,643,579...231,672,818
Ensembl chr 2:231,643,535...231,741,152

Gbp7

guanylate binding protein 7

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:231,275,521...231,297,289
Ensembl chr 2:231,275,640...231,297,278

Gp2

glycoprotein 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619

Gper1

G protein-coupled estrogen receptor 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

Gzmm

granzyme M

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 7:10,011,065...10,016,841
Ensembl chr 7:10,011,066...10,016,665

hepatitis A virus cellular receptor 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

Hck

HCK proto-oncogene, Src family tyrosine kinase

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

Hexim1

HEXIM P-TEFb complex subunit 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189

Hk1

hexokinase 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131

high mobility group box 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

Hmgb1-ps34

high mobility group box 1, pseudogene 34

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:71,363,531...71,364,791
Ensembl chr X:71,363,531...71,364,790

Hmgb1l1

high mobility group box 1 like 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:79,815,176...79,816,529
Ensembl chr 1:79,815,269...79,816,511
Ensembl chr19:79,815,269...79,816,511

Hmgb1l2

high mobility group box 1 like 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:107,671,273...107,672,015
Ensembl chr X:107,671,272...107,672,535

Hmgb1l3

high mobility group box 1 like 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:142,792,113...142,792,852

Hmgb1l5

high mobility group box 1 like 5

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:39,768,658...39,769,408
Ensembl chr10:39,768,658...39,769,293
Ensembl chr19:39,768,658...39,769,293

Hmgb2

high mobility group box 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140

Hmgb2l1

high mobility group box 2-like 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr11:47,252,583...47,253,646
Ensembl chr11:47,252,569...47,253,669
Ensembl chr 1:47,252,569...47,253,669

Hmgb2l2

high mobility group box 2 like 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr14:69,045,590...69,046,623
Ensembl chr14:69,045,641...69,046,640
Ensembl chr 1:69,045,641...69,046,640

Hmgb3

high mobility group box 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292

Hmgb3l1

high mobility group box 3 like 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr14:49,149,415...49,150,197
Ensembl chr14:49,149,580...49,150,176

Ifgga2l1

interferon-gamma-inducible GTPase 2 like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr18:53,761,118...53,770,183
Ensembl chr18:53,748,631...53,772,834

Ifgga2l2

interferon-gamma-inducible GTPase 2 like 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr18:53,870,838...53,890,135
Ensembl chr18:53,870,795...53,892,024

Ifgga4l

interferon-gamma-inducible GTPase 4 like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr18:53,838,426...53,854,858
Ensembl chr18:53,851,449...53,852,696

Ifi27

interferon, alpha-inducible protein 27

involved_in

ISO

(PMID:27194766)

PMID:27194766

NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294

Ifi35

interferon-induced protein 35

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952

Ifi47

interferon gamma inducible protein 47

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:33,297,618...33,305,248
Ensembl chr10:33,285,450...33,306,216

interferon induced with helicase C domain 1

involved_in

ISO
IEA

(PMID:17942531)
GO_REF:0000107
GO_REF:0000043

PMID:17942531

GO_REF:0000043 GO_REF:0000107

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

Ifnb1

interferon beta 1

involved_in

ISO

(PMID:7813427)

PMID:7813427

NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523

Ifnl1

interferon, lambda 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235

Ifnl3

interferon, lambda 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:83,814,456...83,816,096
Ensembl chr 1:83,814,564...83,816,096

Igtp

interferon gamma induced GTPase

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:42,374,590...42,382,410
Ensembl chr10:42,357,400...42,408,247

Il17a

interleukin 17A

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

Il17f

interleukin 17F

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482

Il23a

interleukin 23 subunit alpha

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

Il34

interleukin 34

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000

Inava

innate immunity activator

involved_in

ISO
IEA

(PMID:28436939)
GO_REF:0000107

PMID:28436939

GO_REF:0000107

NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729

Ipo7

importin 7

acts_upstream_of_or_within

ISO
IEA

(PMID:19805818)
GO_REF:0000107

PMID:19805818

GO_REF:0000107

NCBI chr 1:164,062,702...164,102,938
Ensembl chr 1:164,062,702...164,102,938

interleukin-1 receptor-associated kinase 1

involved_in

ISO
IEA
IBA

(PMID:16831874)
GO_REF:0000117
GO_REF:0000033

RGD
UniProt
GO_Central

GO_REF:0000033 GO_REF:0000117

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Irak4

interleukin-1 receptor-associated kinase 4

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837

interferon regulatory factor 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166

Irf5

interferon regulatory factor 5

involved_in

ISO
IEA

(PMID:15665823)
GO_REF:0000107

PMID:15665823

GO_REF:0000107

NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267

immunity-related GTPase M

involved_in

ISO
IEA
IBA
ISS

(PMID:16888103)
GO_REF:0000107
GO_REF:0000043
(PMID:19620982)
GO_REF:0000033
GO_REF:0000024

PMID:16888103 PMID:19620982

GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

Isg15

ISG15 ubiquitin-like modifier

involved_in

ISO
IEA

(PMID:28724761)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

Janus kinase 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Jak3

Janus kinase 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536

Jchain

joining chain of multimeric IgA and IgM

involved_in

ISO
IEA

(PMID:21786026)
GO_REF:0000107

PMID:21786026

GO_REF:0000107

NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298

Kat5

lysine acetyltransferase 5

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:202,895,751...202,903,458

killer cell lectin like receptor D1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518

Klrg1

killer cell lectin like receptor G1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:155,455,465...155,467,301
Ensembl chr 4:155,455,495...155,467,424

killer cell lectin like receptor K1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

Krt16

keratin 16

involved_in

ISO
IEA

(PMID:24218583)
GO_REF:0000107

PMID:24218583

GO_REF:0000107

NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799

Lag3

lymphocyte activating 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404

UniProt
Ensembl
RGD
GO_Central

lipopolysaccharide binding protein

involved_in

IEA
ISO
IBA

GO_REF:0000104
GO_REF:0000107
GO_REF:0000043
(PMID:12932360)
GO_REF:0000033

PMID:12932360

GO_REF:0000033 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

Lcn2

lipocalin 2

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000043
GO_REF:0000107
(PMID:16446425)

PMID:16446425

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

Lgals3

galectin 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899

LOC108349532

high mobility group protein B1 pseudogene

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:163,050,054...163,050,871
Ensembl chr 1:163,050,070...163,051,381
Ensembl chr 1:163,050,070...163,051,381

LOC108350839

high mobility group protein B1-like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:91,306,902...91,309,095
Ensembl chr10:100,935,824...100,936,291

LOC134478941

high mobility group protein B1-like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

LOC134483037

interferon-inducible GTPase 1-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

LOC134483981

high mobility group protein B1-like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Ensembl chr 1:222,796,915...222,798,193

LOC134485624

high mobility group protein B1-like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

Lrrd1

leucine-rich repeats and death domain containing 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:30,263,147...30,293,119
Ensembl chr 4:30,264,862...30,293,173

lactotransferrin

involved_in

ISO

(PMID:9596699)

PMID:9596699

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

Ly86

lymphocyte antigen 86

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260

Ly96

lymphocyte antigen 96

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386

Lyar

Ly1 antibody reactive

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr14:72,576,878...72,590,854
Ensembl chr14:72,576,879...72,590,612

LYN proto-oncogene, Src family tyrosine kinase

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Malt1

MALT1 paracaspase

involved_in

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
(PMID:16831874)

GO_REF:0000033 GO_REF:0000107

NCBI chr18:61,212,290...61,266,272
Ensembl chr18:58,942,299...58,994,260

Masp1

MBL associated serine protease 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

Masp2

MBL associated serine protease 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

Matr3

matrin 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166

Matr3-ps2

matrin 3, pseudogene 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr15:73,882,909...73,886,465

mitochondrial antiviral signaling protein

involved_in
acts_upstream_of_positive_effect

ISS
ISO
IEA

GO_REF:0000024
(PMID:18818105), (PMID:19609254), (PMID:19631370)
GO_REF:0000043
(PMID:23951545)

PMID:18818105 PMID:19609254 PMID:19631370 PMID:23951545

GO_REF:0000024 GO_REF:0000043

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

Mbl1

mannose binding lectin 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174

mannose binding lectin 2

involved_in

ISO
IEA

(PMID:23544079)
GO_REF:0000043

GO_REF:0000043

NCBI chr 1:228,016,439...228,024,736

Mefv

MEFV innate immunity regulator, pyrin

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000043

GO_REF:0000033 GO_REF:0000043

NCBI chr10:12,288,514...12,303,337
Ensembl chr10:11,787,422...11,796,973

multifunctional ROCO family signaling regulator 1

involved_in

ISO
IEA
IBA

(PMID:28471450), (PMID:28609714)
GO_REF:0000107
GO_REF:0000033
(PMID:26599367)

PMID:26599367 PMID:28471450 PMID:28609714

GO_REF:0000033 GO_REF:0000107

NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743

Mfrp

membrane frizzled-related protein

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 8:44,445,636...44,450,859
Ensembl chr 8:44,445,697...44,450,859

Mid2

midline 2

involved_in

ISO
IEA

(PMID:18248090)
GO_REF:0000107

GO_REF:0000107

NCBI chr X:104,354,692...104,456,757
Ensembl chr X:104,355,316...104,453,473

Mif

macrophage migration inhibitory factor

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504

Mir146a

microRNA 146a

involved_in

ISO

(PMID:19333922)

PMID:19333922

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

Mmp3

matrix metallopeptidase 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961

Mpeg1

macrophage expressed 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:209,452,176...209,456,692
Ensembl chr 1:209,452,133...209,458,855

Mptx1

mucosal pentraxin 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:85,727,989...85,731,523
Ensembl chr13:85,728,076...85,731,469

Mr1

major histocompatibility complex, class I-related

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970

Msrb1

methionine sulfoxide reductase B1

involved_in

IEA
ISO
ISS

GO_REF:0000107
GO_REF:0000043
(PMID:23911929)
GO_REF:0000024

PMID:23911929

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609

Muc19

mucin 19, oligomeric

acts_upstream_of_or_within

ISO

(PMID:25512380)

PMID:25512380

NCBI chr 7:123,017,896...123,139,053
Ensembl chr 7:123,017,896...123,139,053

Mx1

MX dynamin like GTPase 1

involved_in

ISS
IEA

GO_REF:0000024
GO_REF:0000043

GO_REF:0000024 GO_REF:0000043

NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507

Mx2

MX dynamin like GTPase 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342

MYD88, innate immune signal transduction adaptor

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000043

GO_REF:0000033 GO_REF:0000043

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

N4bp1

Nedd4 binding protein 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570

N4bp3

Nedd4 binding protein 3

acts_upstream_of_positive_effect

ISO

(PMID:23951545)

PMID:23951545

NCBI chr10:35,898,031...35,906,704
Ensembl chr10:35,899,096...35,907,001

Nagk

N-acetylglucosamine kinase

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137

Ndufs4

NADH:ubiquinone oxidoreductase subunit S4

acts_upstream_of_or_within

ISO

MGI:3793713 (PMID:25652399)

PMID:25652399

NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846

Nedd4

NEDD4 E3 ubiquitin protein ligase

acts_upstream_of_positive_effect

ISO
IEA

(PMID:23951545)
GO_REF:0000107

PMID:23951545

GO_REF:0000107

NCBI chr 8:82,264,751...82,349,642
Ensembl chr 8:73,383,695...73,468,951

Neurl3

neuralized E3 ubiquitin protein ligase 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:45,990,373...45,998,470
Ensembl chr 9:38,494,489...38,502,649

Nlrc4

NLR family, CARD domain containing 4

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248

NLR family, CARD domain containing 5

involved_in

ISO

(PMID:20434986)

PMID:20434986

NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121

NLR family, pyrin domain containing 1A

involved_in

IEA

GO_REF:0000043
GO_REF:0000002

GO_REF:0000002 GO_REF:0000043

NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180

Nlrp1b

NLR family, pyrin domain containing 1B

involved_in

IEA

GO_REF:0000043
GO_REF:0000002

GO_REF:0000002 GO_REF:0000043

NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774

Nlrp3

NLR family, pyrin domain containing 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

NLR family, pyrin domain containing 6

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113

Nlrp9

NLR family, pyrin domain containing 9

involved_in

ISO
IEA

(PMID:28636595)
GO_REF:0000043

PMID:28636595

GO_REF:0000043

NCBI chr 1:68,291,180...68,341,512
Ensembl chr 1:68,291,180...68,341,512

Nlrx1

NLR family member X1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484

N-myc (and STAT) interactor

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498

Nod1

nucleotide-binding oligomerization domain containing 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404

nucleotide-binding oligomerization domain containing 2

involved_in

ISO
IEA

(PMID:23806334)
GO_REF:0000107
GO_REF:0000043

PMID:23806334

GO_REF:0000043 GO_REF:0000107

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Nono

non-POU domain containing, octamer-binding

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:66,554,131...66,571,992
Ensembl chr X:66,554,098...66,571,952

defensin NP-4 precursor

involved_in

ISO

(PMID:2500436)

PMID:2500436

NCBI chr16:70,494,607...70,497,261
Ensembl chr16:70,342,529...70,497,202

Npy

neuropeptide Y

involved_in

ISO

(PMID:18603306)

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

Nqo1

NAD(P)H quinone dehydrogenase 1

involved_in

ISO
IEA

MGI:2388490 (PMID:29934320)
GO_REF:0000107

PMID:29934320

GO_REF:0000107

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

Nr1h4

nuclear receptor subfamily 1, group H, member 4

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

Nrros

negative regulator of reactive oxygen species

NOT|involved_in

ISS
ISO

GO_REF:0000024
(PMID:29909984)

PMID:29909984

GO_REF:0000024

NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142

2'-5' oligoadenylate synthetase 1A

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

Oas1b

2-5 oligoadenylate synthetase 1B

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242

Oas1d

2'-5' oligoadenylate synthetase 1D

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,648,583...35,658,037
Ensembl chr12:35,648,583...35,657,902

Oas1e

2'-5' oligoadenylate synthetase 1E

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,750,359...35,759,304
Ensembl chr12:35,750,359...35,759,301

Oas1f

2 ' -5 ' oligoadenylate synthetase 1F

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,697,024...35,706,617
Ensembl chr12:35,697,015...35,706,323

Oas1h

2 ' -5 ' oligoadenylate synthetase 1H

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,682,862...35,695,717
Ensembl chr12:35,683,699...35,693,366

Oas1i

2 ' -5 ' oligoadenylate synthetase 1I

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604

Oas1k

2 ' -5 ' oligoadenylate synthetase 1K

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,762,483...35,771,710
Ensembl chr12:35,762,468...35,771,710

Oas2

2'-5' oligoadenylate synthetase 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371

2'-5'-oligoadenylate synthetase 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781

2'-5'-oligoadenylate synthetase-like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641

Oasl2

2'-5' oligoadenylate synthetase-like 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:41,710,072...41,722,687
Ensembl chr12:41,709,435...41,722,547

Otulin

OTU deubiquitinase with linear linkage specificity

involved_in

ISO
IEA
IBA

(PMID:23806334), (PMID:26997266)
GO_REF:0000107
GO_REF:0000033

PMID:23806334 PMID:26997266

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:78,290,437...78,316,633
Ensembl chr 2:78,290,959...78,316,422

Padi4

peptidyl arginine deiminase 4

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:153,041,351...153,074,412
Ensembl chr 5:153,041,352...153,074,362

Parp1

poly (ADP-ribose) polymerase 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404

Pfpl

pore forming protein-like

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:209,412,059...209,415,339
Ensembl chr 1:209,412,515...209,414,608

Pglyrp1

peptidoglycan recognition protein 1

involved_in

IEA

GO_REF:0000043
GO_REF:0000002

GO_REF:0000002 GO_REF:0000043

NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001

Pja2

praja ring finger ubiquitin ligase 2

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:28471450)

PMID:28471450

GO_REF:0000024 GO_REF:0000107

NCBI chr 9:111,403,624...111,453,703
Ensembl chr 9:103,956,678...104,006,783

Plpp6

phospholipid phosphatase 6

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:226,679,100...226,681,952
Ensembl chr 1:226,679,100...226,681,949

Pml

PML nuclear body scaffold

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971

Polr3a

RNA polymerase III subunit A

involved_in

ISO

(PMID:19609254)

PMID:19609254

NCBI chr16:49,178...88,178
Ensembl chr16:49,521...88,172

Polr3c

RNA polymerase III subunit C

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:184,246,201...184,262,150
Ensembl chr 2:184,246,204...184,262,208

Ppp1r14b

protein phosphatase 1, regulatory (inhibitor) subunit 14B

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
Ensembl chr12:204,163,299...204,167,319

Ppp1r14bl1

protein phosphatase 1, regulatory (inhibitor) subunit 14B like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:19,522,009...19,522,605
Ensembl chr12:15,974,864...15,975,648

Ppp6c

protein phosphatase 6, catalytic subunit

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:22,929,816...22,962,123
Ensembl chr 3:22,931,577...22,962,113

Pqbp1

polyglutamine binding protein 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:14,603,516...14,608,091
Ensembl chr X:14,603,539...14,608,087

Prkd1

protein kinase D1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042

Pspc1

paraspeckle component 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202

Ptx3

pentraxin 3

involved_in

ISO
IBA

(PMID:23544079)
GO_REF:0000033

GO_REF:0000033

NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323

Pycard

PYD and CARD domain containing

involved_in

IEA

GO_REF:0000043
GO_REF:0000002

GO_REF:0000002 GO_REF:0000043

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

Rab2b

RAB2B, member RAS oncogene family

involved_in

ISO
IEA

(PMID:28930687)
GO_REF:0000107

PMID:28930687

GO_REF:0000107

NCBI chr15:24,968,364...24,988,990
Ensembl chr15:24,968,803...24,989,113

Rarres2

retinoic acid receptor responder 2

involved_in

ISO
IEA
IBA

(PMID:23527010)
GO_REF:0000107
GO_REF:0000033

PMID:23527010

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556

Rb1cc1

RB1-inducible coiled-coil 1

acts_upstream_of_or_within

ISO
IEA

(PMID:26764600)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560

Rel

REL proto-oncogene, NF-kB subunit

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892

RELA proto-oncogene, NF-kB subunit

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Relb

RELB proto-oncogene, NF-kB subunit

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

Rfpl4a

ret finger protein-like 4A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:77,757,811...77,764,270
Ensembl chr 1:68,728,964...68,735,423

RGD1309362

similar to interferon-inducible GTPase

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

RGD1559575

similar to novel protein

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:33,252,146...33,276,364
Ensembl chr10:33,252,134...33,276,225

Rhot1

ras homolog family member T1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:65,198,700...65,262,807
Ensembl chr10:65,170,560...65,262,804

RNA sensor RIG-1

involved_in

ISO
IEA

(PMID:19609254), (PMID:19631370)
GO_REF:0000107
GO_REF:0000043
(PMID:17942531)

PMID:17942531 PMID:19609254 PMID:19631370

GO_REF:0000043 GO_REF:0000107

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

Riok3

RIO kinase 3

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343

RGD
UniProt
Ensembl
GO_Central

receptor-interacting serine-threonine kinase 2

involved_in

ISO
IEA
IBA

(PMID:23806334)
GO_REF:0000043
GO_REF:0000107
(PMID:21469090)
GO_REF:0000033

PMID:21469090 PMID:23806334

GO_REF:0000033 GO_REF:0000043 GO_REF:0000107

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

Rnase3

ribonuclease A family member 3

involved_in

ISO

(PMID:23992292)

PMID:23992292

NCBI chr15:24,511,894...24,512,764
Ensembl chr15:24,511,891...24,512,790

Rnase6

ribonuclease A family member 6

involved_in

ISO
IBA

(PMID:25075772)
GO_REF:0000033

PMID:25075772

GO_REF:0000033

NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328

ring finger protein 135

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:65,668,441...65,687,671
Ensembl chr10:65,170,560...65,262,804

Rnf166

ring finger protein 166

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr19:67,437,974...67,447,814
Ensembl chr19:50,529,434...50,539,274

Rnf170

ring finger protein 170

acts_upstream_of_or_within

ISO
IEA

(PMID:31076723)
GO_REF:0000107

PMID:31076723

GO_REF:0000107

NCBI chr16:72,631,638...72,656,893
Ensembl chr16:65,928,895...65,954,083

Rnf185

ring finger protein 185

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr14:82,516,153...82,554,199
Ensembl chr14:78,292,516...78,329,864

Rnf39

ring finger protein 39

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,604,794...1,610,283

Rps7

ribosomal protein S7

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145

Rsad2

radical S-adenosyl methionine domain containing 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

S100a8

S100 calcium binding protein A8

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

S100a9

S100 calcium binding protein A9

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

Sarm1

sterile alpha and TIR motif containing 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822

Sdhaf4

succinate dehydrogenase complex assembly factor 4

acts_upstream_of_or_within

ISO

(PMID:19805818)

PMID:19805818

NCBI chr 9:26,408,332...26,416,478

Senp7

SUMO specific peptidase 7

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711

Serinc5

serine incorporator 5

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346

Serping1

serpin family G member 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

Sfpq

splicing factor proline and glutamine rich

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472

Sftpd

surfactant protein D

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927

Sh2d1a

SH2 domain containing 1A

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:121,373,693...121,401,923

Skp2

S-phase kinase associated protein 2

involved_in

ISO
IEA

(PMID:27194766)
GO_REF:0000107

PMID:27194766

GO_REF:0000107

NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338

Slc15a2

solute carrier family 15 member 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225

Slc15a3

solute carrier family 15 member 3

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157

solute carrier family 15 member 4

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

Slpi

secretory leukocyte peptidase inhibitor

involved_in

ISO

(PMID:18322212)

PMID:18322212

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

Slpi-ps1

secretory leukocyte peptidase inhibitor, pseudogene 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,019,109...153,021,371
Ensembl chr 3:153,019,109...153,021,360
Ensembl chr 3:153,019,109...153,021,360

Slpi-ps2

secretory leukocyte peptidase inhibitor, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,056,907...153,061,611
Ensembl chr 3:153,019,114...153,059,479
Ensembl chr 3:153,019,114...153,059,479

Sp110

SP110 nuclear body protein

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:86,200,503...86,225,355
Ensembl chr 9:86,200,503...86,222,670

Spon2

spondin 2

acts_upstream_of_or_within
involved_in

ISO
IEA

MGI:3026870 (PMID:14691481)
GO_REF:0000043
GO_REF:0000107

PMID:14691481

GO_REF:0000043 GO_REF:0000107

NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996

UniProt
RGD
Ensembl
GO_Central

stimulator of interferon response cGAMP interactor 1

involved_in

ISS
ISO
IEA
IBA

GO_REF:0000024
(PMID:18818105), (PMID:19433799), (PMID:21074459), (PMID:23910378), (PMID:25254379)
GO_REF:0000107
GO_REF:0000043
(PMID:19433799), (PMID:19776740), (PMID:23910378)
GO_REF:0000033

PMID:18818105 PMID:19433799 PMID:19776740 PMID:21074459 PMID:23910378 More...

GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

Syk

spleen associated tyrosine kinase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000043
(PMID:15845454)
GO_REF:0000107

PMID:15845454

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107

NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410

Tac1

tachykinin, precursor 1

involved_in

ISO

(PMID:18603306)

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

TANK-binding kinase 1

involved_in

ISO
IEA

(PMID:25636800)
GO_REF:0000107

PMID:25636800

GO_REF:0000107

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

Tbkbp1

TBK1 binding protein 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:82,120,558...82,135,749
Ensembl chr10:82,120,564...82,134,352

TIR domain containing adaptor molecule 1

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

TIR domain containing adaptor molecule 2

involved_in

IEA

GO_REF:0000043

PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836

GO_REF:0000043

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

Tifa

TRAF-interacting protein with forkhead-associated domain

involved_in

ISS
IBA
IEA
ISO

GO_REF:0000024
GO_REF:0000033
GO_REF:0000043
(PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)

UniProt
GO_Central
RGD

GO_REF:0000024 GO_REF:0000033 GO_REF:0000043

NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841

TIR domain containing adaptor protein

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Tlr1

toll-like receptor 1

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125

Tlr10

toll-like receptor 10

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr14:43,400,843...43,414,056
Ensembl chr14:43,406,217...43,413,917

Tlr11

toll-like receptor 11

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr15:23,545,408...23,549,849
Ensembl chr15:23,545,408...23,549,849

Tlr12

toll-like receptor 12

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:140,961,166...140,964,171
Ensembl chr 5:140,959,996...140,964,816

Tlr13

toll-like receptor 13

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:71,220,288...71,241,899
Ensembl chr X:71,220,367...71,242,376

toll-like receptor 2

involved_in

ISO
IEA

(PMID:15356140)
GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

toll-like receptor 3

involved_in

ISO
IEA

(PMID:15356140)
GO_REF:0000043
GO_REF:0000107

GO_REF:0000043 GO_REF:0000107

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

toll-like receptor 4

involved_in

ISO
IEA

(PMID:15356140)
GO_REF:0000104
GO_REF:0000043
GO_REF:0000107

GO_REF:0000043 GO_REF:0000104 GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tlr5

toll-like receptor 5

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738

toll-like receptor 6

involved_in

IEA

GO_REF:0000104
GO_REF:0000043

GO_REF:0000043 GO_REF:0000104

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

toll-like receptor 7

involved_in

ISO
IEA

(PMID:35477763)
GO_REF:0000107
GO_REF:0000043

PMID:35477763

GO_REF:0000043 GO_REF:0000107

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

toll-like receptor 8

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549

toll-like receptor 9

involved_in

IEA
ISO

GO_REF:0000107
GO_REF:0000043
(PMID:15356140)

GO_REF:0000043 GO_REF:0000107

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Tmem106a

transmembrane protein 106A

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892

Tmem33

transmembrane protein 33

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr14:40,888,485...40,910,715
Ensembl chr14:40,885,712...40,910,715

Tmem43

transmembrane protein 43

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:123,977,680...123,992,823
Ensembl chr 4:123,977,625...123,992,825

Tmem45b

transmembrane protein 45b

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453

Tnfaip8l2

TNF alpha induced protein 8 like 2

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:182,710,433...182,726,724
Ensembl chr 2:182,709,378...182,726,760

Tollip

toll interacting protein

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625

Traf2

Tnf receptor-associated factor 2

acts_upstream_of_positive_effect

ISO
IEA

(PMID:23951545)
GO_REF:0000107

PMID:23951545

GO_REF:0000107

NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538

Traf3

Tnf receptor-associated factor 3

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:130,206,484...130,305,481

TNF receptor associated factor 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507

Trem1

triggering receptor expressed on myeloid cells 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203

three prime repair exonuclease 1

acts_upstream_of_or_within

ISO
IEA

MGI:3052754 (PMID:23160154)
GO_REF:0000107

PMID:23160154

GO_REF:0000107

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

Tril

TLR4 interactor with leucine-rich repeats

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172

Trim10

tripartite motif-containing 10

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr20:1,694,771...1,703,724
Ensembl chr20:1,689,562...1,698,252

Trim11

tripartite motif-containing 11

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000033

RGD
UniProt
GO_Central
Ensembl

GO_REF:0000033 GO_REF:0000107

NCBI chr10:44,255,019...44,270,711
Ensembl chr10:43,758,354...43,771,138

Trim13

tripartite motif-containing 13

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000043
GO_REF:0000033
GO_REF:0000107

RGD
Ensembl
InterPro
GO_Central

GO_REF:0000033 GO_REF:0000043 GO_REF:0000107

NCBI chr15:39,909,587...39,948,719
Ensembl chr15:35,734,107...35,772,677

Trim14

tripartite motif-containing 14

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr 5:65,596,149...65,620,434
Ensembl chr 5:60,800,032...60,824,858

Trim15

tripartite motif containing 15

involved_in

ISO

(PMID:18248090)

NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249

Trim17

tripartite motif-containing 17

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:44,242,688...44,250,504
Ensembl chr10:43,740,604...43,750,919

tripartite motif-containing 21

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:166,376,829...166,399,441
Ensembl chr 1:156,964,913...156,987,440

tripartite motif-containing 25

involved_in

ISO
IEA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000043

GO_REF:0000043 GO_REF:0000107

NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257

Trim26

tripartite motif-containing 26

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000043
GO_REF:0000033

GO_REF:0000033 GO_REF:0000043 GO_REF:0000107

NCBI chr20:1,711,564...1,736,389
Ensembl chr20:1,709,788...1,731,120

Trim27

tripartite motif-containing 27

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr17:48,233,999...48,246,348
Ensembl chr17:43,538,285...43,550,643

Trim28

tripartite motif-containing 28

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
MGI:2143362 (PMID:19270682)
GO_REF:0000033

PMID:18248090 PMID:19270682

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:73,652,709...73,659,380

Trim30c

tripartite motif-containing 30C

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:168,174,528...168,200,343
Ensembl chr 1:158,765,969...158,787,183

Trim30d

tripartite motif-containing 30D

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:168,207,166...168,225,780
Ensembl chr 1:158,720,410...158,814,012

tripartite motif-containing 31

involved_in

ISO
IEA
IBA

(PMID:18248090)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494

Trim32

tripartite motif-containing 32

involved_in

ISO

(PMID:18248090)

NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:78,999,389...79,022,018

Trim34

tripartite motif-containing 34

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:168,119,043...168,130,544
Ensembl chr 1:158,707,172...158,718,674

Trim35

tripartite motif-containing 35

involved_in

IEA
IBA
ISO

GO_REF:0000107
GO_REF:0000033
(PMID:18248090)

Ensembl
GO_Central
RGD

GO_REF:0000033 GO_REF:0000107

NCBI chr15:44,669,222...44,685,766
Ensembl chr15:40,493,755...40,510,240

Trim39

tripartite motif-containing 39

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr20:2,008,528...2,022,383
Ensembl chr20:1,983,533...2,020,117

Trim40

tripartite motif-containing 40

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr20:1,680,554...1,691,123
Ensembl chr20:1,676,270...1,685,214

Trim41

tripartite motif-containing 41

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:33,676,348...33,687,432
Ensembl chr10:33,175,213...33,186,694

Trim43a

tripartite motif-containing 43A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 8:98,425,912...98,478,569
Ensembl chr 8:89,562,568...89,568,716

Trim44

tripartite motif-containing 44

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:109,048,643...109,183,821
Ensembl chr 3:88,592,719...88,729,188

Trim5

tripartite motif-containing 5

involved_in

ISO
IBA

(PMID:18248090)
GO_REF:0000033

GO_REF:0000033

NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:158,720,410...158,814,012

Trim50

tripartite motif-containing 50

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:26,937,349...26,954,286
Ensembl chr12:21,300,785...21,317,668

Trim54

tripartite motif-containing 54

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 6:30,959,306...30,978,475
Ensembl chr 6:25,239,340...25,258,511

Trim55

tripartite motif-containing 55

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 2:104,016,361...104,058,302
Ensembl chr 2:102,088,443...102,142,168

tripartite motif containing 56

involved_in

ISO

(PMID:18248090)

NCBI chr12:25,193,224...25,204,032
Ensembl chr12:19,551,521...19,567,462

Trim58

tripartite motif-containing 58

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:43,523,341...43,536,435
Ensembl chr10:43,022,996...43,034,476

Trim59

tripartite motif-containing 59

involved_in

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
(PMID:18248090)

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:155,579,183...155,593,450
Ensembl chr 2:153,268,584...153,281,031

Trim6

tripartite motif containing 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914

Trim62

tripartite motif-containing 62

involved_in

ISO
IBA

(PMID:18248090)
GO_REF:0000033

GO_REF:0000033

NCBI chr 5:146,516,349...146,545,015
Ensembl chr 5:141,231,523...141,259,915

Trim63

tripartite motif containing 63

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:146,533,507...146,547,322

tripartite motif-containing 65

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971

Trim68

tripartite motif containing 68

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:166,525,981...166,539,407
Ensembl chr 1:157,114,044...157,127,477

Trim69

tripartite motif-containing 69

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:129,565,060...129,585,629
Ensembl chr 3:109,111,468...109,132,037

Trim7

tripartite motif-containing 7

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:33,706,614...33,722,609
Ensembl chr10:33,205,491...33,221,468

Trim72

tripartite motif containing 72

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:192,044,220...192,052,080
Ensembl chr 1:182,613,712...182,621,606

Trim8

tripartite motif-containing 8

involved_in

ISO

(PMID:18248090)

NCBI chr 1:255,311,039...255,325,937
Ensembl chr 1:245,369,632...245,384,513

Trim80

tripartite motif protein 80

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr10:100,682,826...100,691,152
Ensembl chr10:100,682,830...100,691,151

Triml1

tripartite motif family-like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:55,727,383...55,737,770
Ensembl chr16:48,997,252...49,005,417

Triml2

tripartite motif family-like 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:55,677,142...55,693,379
Ensembl chr16:48,944,838...48,955,453

Ttc4

tetratricopeptide repeat domain 4

involved_in

ISO

(PMID:29251827)

PMID:29251827

NCBI chr 5:121,444,712...121,462,381
Ensembl chr 5:121,445,740...121,462,287

Uba7

ubiquitin-like modifier activating enzyme 7

involved_in

ISO
IEA
IBA

(PMID:28724761)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:117,543,902...117,552,709
Ensembl chr 8:108,665,292...108,674,099

Ube2l6

ubiquitin-conjugating enzyme E2L 6

involved_in

ISO
IEA

(PMID:28724761)
GO_REF:0000107

GO_REF:0000107

NCBI chr 3:90,279,705...90,294,721
Ensembl chr 3:69,873,424...69,888,048

Umod

uromodulin

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302

Vip

vasoactive intestinal peptide

involved_in

ISO

(PMID:18603306)

NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216

Vnn1

vanin 1

involved_in

ISO
IEA

(PMID:14966568)
GO_REF:0000107

PMID:14966568

GO_REF:0000107

NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395

Wap

whey acidic protein

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr14:81,503,123...81,505,244
Ensembl chr14:81,503,123...81,505,219

Wfdc10a

WAP four-disulfide core domain 10A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,390,067...153,391,420
Ensembl chr 3:153,390,067...153,391,420

Wfdc12

WAP four-disulfide core domain 12

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:152,861,461...152,862,784
Ensembl chr 3:152,862,341...152,862,690

Wfdc13

WAP four-disulfide core domain 13

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,419,553...153,421,306
Ensembl chr 3:153,419,648...153,421,221

Wfdc15b

WAP four-disulfide core domain 15B

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:152,889,453...152,899,392
Ensembl chr 3:152,890,216...152,896,900

Wfdc16

WAP four-disulfide core domain 16

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,366,913...153,370,083
Ensembl chr 3:153,366,976...153,370,056

Wfdc17

WAP four-disulfide core domain 17

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801

Wfdc18

WAP four-disulfide core domain 18

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,588,818...68,590,972
Ensembl chr10:68,588,818...68,589,671

Wfdc2

WAP four-disulfide core domain 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,286,946...153,314,832
Ensembl chr 3:153,286,131...153,292,807

Wfdc21

WAP four-disulfide core domain 21

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:68,627,836...68,633,705
Ensembl chr10:68,627,820...68,633,701

Wfdc3

WAP four-disulfide core domain 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,464,862...153,478,952
Ensembl chr 3:153,464,862...153,478,952

Wfdc5

WAP four-disulfide core domain 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:152,849,025...152,854,868
Ensembl chr 3:152,849,025...152,854,904

Wfdc9

WAP four-disulfide core domain 9

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 3:153,380,554...153,389,055
Ensembl chr 3:153,380,649...153,391,261

Wrnip1

WRN helicase interacting protein 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659

Z-DNA binding protein 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:161,993,351...162,003,870

Zc3hav1

zinc finger CCCH-type containing, antiviral 1

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428

Zdhhc18

zinc finger DHHC-type palmitoyltransferase 18

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:151,105,303...151,143,843
Ensembl chr 5:145,831,446...145,859,993

Zdhhc5

zinc finger DHHC-type palmitoyltransferase 5

involved_in

IEA

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921

innate immune response in mucosa

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apoa4

apolipoprotein A4

involved_in

IEA
ISO

GO_REF:0000107
(PMID:15254593)

PMID:15254593

GO_REF:0000107

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

Bpifb1

BPI fold containing family B, member 1

involved_in

ISO
IBA
IEA

(PMID:21900486)
GO_REF:0000033
GO_REF:0000107

PMID:21900486

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256

cathelicidin antimicrobial peptide

involved_in

ISO
IEA

(PMID:12860195)
GO_REF:0000107

GO_REF:0000107

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

Cldn2

claudin 2

involved_in

ISO

(PMID:28618266)

PMID:28618266

NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838

Defa24

defensin alpha 24

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,349,550...70,350,582
Ensembl chr16:70,349,567...70,350,603

Defa3

defensin alpha 3

involved_in

IBA
ISO

GO_REF:0000033
(PMID:12860195)

GO_REF:0000033

NCBI chr16:70,533,436...70,535,592
Ensembl chr16:70,533,436...70,535,604

Defa31

defensin alpha 31

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,513,892...70,516,234
Ensembl chr16:70,514,248...70,515,024

defensin alpha 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836

Defa6

defensin alpha 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,405,223...70,406,237
Ensembl chr16:70,405,268...70,406,142

Defa8

defensin alpha 8

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,433,121...70,434,154
Ensembl chr16:70,433,166...70,434,059

Defa9

defensin alpha 9

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,481,813...70,482,803
Ensembl chr16:70,481,821...70,482,717

Defal1

defensin alpha-like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,371,492...70,372,481
Ensembl chr16:70,371,518...70,372,353

Defb1

defensin beta 1

involved_in

ISO
IBA

(PMID:12860195)
GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

Defb10

defensin beta 10

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,202,599...70,212,734
Ensembl chr16:70,202,655...70,212,707

Defb11

defensin beta 11

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,156,044...70,163,062
Ensembl chr16:70,156,141...70,163,068

Defb2

defensin beta 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,231,870...70,245,817
Ensembl chr16:70,231,945...70,245,784

Defb37

defensin beta 37

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,783,532...70,796,798
Ensembl chr16:70,783,554...70,796,892

Defb38

defensin beta 38

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,756,370...70,759,701
Ensembl chr16:70,756,409...70,759,641

Defb39

defensin beta 39

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,740,347...70,744,157
Ensembl chr16:70,734,713...70,744,192

Defb9

defensin beta 9

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,180,692...70,183,602
Ensembl chr16:70,180,771...70,183,554

Ear1

eosinophil-associated, ribonuclease A family, member 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,555,280...24,556,189
Ensembl chr15:24,555,298...24,556,199

Ear1l1

eosinophil-associated, ribonuclease A family, member 1 like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,486,827...24,487,702
Ensembl chr15:24,486,826...24,487,691

ENSRNOG00000064390

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr16:70,426,027...70,475,448

ENSRNOG00000069429

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr15:24,550,323...24,551,150

Fau

FAU ubiquitin like and ribosomal protein S30 fusion

involved_in

ISO

(PMID:12860195)

NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
Ensembl chr 1:203,350,189...203,351,742
Ensembl chr 6:203,350,189...203,351,742

H2bc12

H2B clustered histone 12

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,485,699...42,486,162

H2bc18

H2B clustered histone 18

involved_in

ISO

(PMID:12860195)

NCBI chr 2:183,838,331...183,842,769
Ensembl chr 2:183,838,334...183,841,529

H2bc3

H2B clustered histone 3

involved_in

ISO

(PMID:12860195)

NCBI chr17:41,380,056...41,380,686

H2bc6

H2B clustered histone 6

involved_in

ISO

(PMID:12860195)

NCBI chr17:41,520,775...41,521,238

H2bc8

H2B clustered histone 8

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,708,658...42,709,408

H2bc9

H2B clustered histone 9

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,470,593...42,478,590

H2bu1

H2B.U histone 1

involved_in

ISO

(PMID:12860195)

NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277

Hist1h2bc

histone cluster 1, H2bc

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642

Hist1h2bd

histone cluster 1 H2B family member D

involved_in

ISO

(PMID:12860195)

NCBI chr17:42,792,887...42,793,268

Hist1h2bq

histone cluster 1 H2B family member Q

involved_in

ISO

(PMID:12860195)

NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153
Ensembl chr17:41,429,164...41,442,153
Ensembl chr17:41,429,164...41,442,153

Hist2h2be

histone cluster 2 H2B family member E

involved_in

ISO

(PMID:12860195)

NCBI chr 2:183,780,583...183,783,030

Il4

interleukin 4

involved_in

ISO

(PMID:9973465)

PMID:9973465

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

LOC100361866

eosinophil cationic protein-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,535,701...24,536,571
Ensembl chr15:24,535,700...24,536,592

lactotransferrin

involved_in

ISO

(PMID:12037568)

PMID:12037568

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

ISO

MGI:3529594 (PMID:15692051)

PMID:15692051

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

defensin NP-4 precursor

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,494,607...70,497,261
Ensembl chr16:70,342,529...70,497,202

Pla2g1b

phospholipase A2 group IB

involved_in

ISO

(PMID:12860195)

NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226

Ratnp-3b

defensin rat NP-3 precursor

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr16:70,544,364...70,546,533
Ensembl chr16:70,513,888...70,546,522

Rnase17

ribonuclease 17

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,499,178...24,500,140
Ensembl chr15:24,499,178...24,500,095

Rnase2

ribonuclease A family member 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479

Rnase3

ribonuclease A family member 3

involved_in

ISO
IBA

(PMID:12860195)
GO_REF:0000033

GO_REF:0000033

NCBI chr15:24,511,894...24,512,764
Ensembl chr15:24,511,891...24,512,790

Rpl39

ribosomal protein L39

involved_in

ISO

(PMID:12860195)

innate immune response-activating signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

toll-like receptor 4

IMP

RGD

PMID:19226379

RGD:2312509

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

killing by host of symbiont cells

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07006691.1

acts_upstream_of_or_within

IEA

GO_REF:0000107

GO_REF:0000107

Ensembl chr 1:228,016,498...228,043,066

cathelicidin antimicrobial peptide

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:16020269)
GO_REF:0000107
MGI:2182791 (PMID:16177355)

PMID:16020269 PMID:16177355

GO_REF:0000107

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

Dao

D-amino-acid oxidase

involved_in

ISO
IEA

(PMID:27670111)
GO_REF:0000107

PMID:27670111

GO_REF:0000107

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

defensin alpha 5

involved_in

ISO

(PMID:9169780)

PMID:9169780

NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836

Defb14

defensin beta 14

involved_in

ISO

(PMID:16436752)

PMID:16436752

NCBI chr16:70,663,443...70,668,473
Ensembl chr16:70,663,333...70,666,540

Mbl1

mannose binding lectin 1

acts_upstream_of_or_within

ISO

MGI:96924 (PMID:15148336)

PMID:15148336

NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174

mannose binding lectin 2

acts_upstream_of_or_within

ISO
IEA

MGI:96923 (PMID:15148336)
GO_REF:0000107

PMID:15148336

GO_REF:0000107

NCBI chr 1:228,016,439...228,024,736

MDA-5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

interferon induced with helicase C domain 1

involved_in

ISO
IEA
IBA

(PMID:17600090), (PMID:19211564), (PMID:33727702)
GO_REF:0000107
GO_REF:0000033

PMID:17600090 PMID:19211564 PMID:33727702

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

2'-5'-oligoadenylate synthetase 3

involved_in

ISO
IEA

(PMID:30078389)
GO_REF:0000107

GO_REF:0000107

NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781

MyD88-dependent toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lrrfip2

LRR binding FLII interacting protein 2

acts_upstream_of_or_within

ISO

(PMID:19265123)

PMID:19265123

NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255

MyD88-dependent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

high mobility group box 1

involved_in

ISO

(PMID:14660645)

PMID:14660645

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

Hspd1

heat shock protein family D (Hsp60) member 1

involved_in

ISO

(PMID:16148103)

PMID:16148103

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

PMID:12719478 PMID:12872135 PMID:14764662

MYD88, innate immune signal transduction adaptor

involved_in
acts_upstream_of_or_within

IEA
ISO

GO_REF:0000002
GO_REF:0000107
MGI:1346060|MGI:2385681 (PMID:12719478), (PMID:12872135), (PMID:14764662)

InterPro
Ensembl
RGD

GO_REF:0000002 GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

Reg3g

regenerating family member 3 gamma

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:17635956)

PMID:17635956

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723

toll-like receptor 2

acts_upstream_of_or_within

ISO

MGI:108005 (PMID:12719478)

PMID:12719478

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

PMID:20037584 PMID:38670073

toll-like receptor 4

involved_in

IEA
ISO
IBA

GO_REF:0000107
(PMID:20037584), (PMID:38670073)
UniProtKB:Q9EPW9 (PMID:20037584)
GO_REF:0000033

Ensembl
RGD
GO_Central

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

toll-like receptor 6

involved_in

ISO
IEA

(PMID:20037584)
GO_REF:0000107
UniProtKB:Q9QUK6 (PMID:20037584)

GO_REF:0000107

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

toll-like receptor 9

involved_in

ISO
IEA

UniProtKB:P22366 (PMID:18820679)
GO_REF:0000107

PMID:18820679

GO_REF:0000107

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Tnip1

TNFAIP3 interacting protein 1

involved_in

ISO

(PMID:22011580)

PMID:22011580

NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625

MyD88-independent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lrrfip2

LRR binding FLII interacting protein 2

acts_upstream_of_or_within

ISO

(PMID:19265123)

PMID:19265123

NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255

TIR domain containing adaptor molecule 1

acts_upstream_of_or_within

ISO

MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135)

PMID:12855817 PMID:12872135

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

Tnip3

TNFAIP3 interacting protein 3

involved_in

ISO

(PMID:17088249)

PMID:17088249

NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605

natural killer cell activation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd244

CD244 molecule

involved_in

ISO

(PMID:11714776)
(PMID:15905190)

PMID:11714776 PMID:15905190

NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492

Cd244l1

CD244 molecule like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:84,018,887...84,036,612
Ensembl chr13:84,020,095...84,036,100

ENSRNOG00000065554

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 5:103,321,196...103,322,285

Ifna1

interferon, alpha 1

acts_upstream_of_or_within
involved_in

ISO
IBA

(PMID:19130550)
GO_REF:0000033

PMID:19130550

GO_REF:0000033

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

Ifna4

interferon, alpha 4

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052

Ifna4l1

interferon, alpha 4 like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302

Ifna5

interferon, alpha 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,187,852...103,188,430

Ifnb1

interferon beta 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523

Ifnk

interferon kappa

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281

Il12b

interleukin 12B

IMP

RGD

PMID:14960310

RGD:1600048

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

LOC120103158

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,378,576...103,379,147
Ensembl chr 5:103,378,593...103,379,147

LOC120103159

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,407,135...103,407,884
Ensembl chr 5:103,407,283...103,407,837

LOC120103160

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,426,092...103,427,016
Ensembl chr 5:103,426,387...103,426,941

LOC120103161

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,441,204...103,442,180
Ensembl chr 5:103,441,540...103,442,094

LOC120103162

interferon alpha-1-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,455,380...103,455,934
Ensembl chr 5:103,455,380...103,455,934

natural killer cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Coro1a

coronin 1A

involved_in

ISO
IEA

(PMID:24760828)
GO_REF:0000107

PMID:24760828

GO_REF:0000107

NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:181,295,562...181,300,534

Fcgr3a

Fc gamma receptor 3A

involved_in

ISO

(PMID:25786175), (PMID:28652325)

PMID:25786175 PMID:28652325

NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921

Kctd9

potassium channel tetramerization domain containing 9

acts_upstream_of_or_within

ISO

(PMID:31024568)

PMID:31024568

NCBI chr15:41,942,165...41,969,862
Ensembl chr15:41,942,381...41,969,862

Nkg7

natural killer cell granule protein 7

involved_in

ISO

(PMID:32839608), (PMID:33911019)

PMID:32839608 PMID:33911019

NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983

Rab27a

RAB27A, member RAS oncogene family

acts_upstream_of_or_within

ISO
IEA

MGI:1856656 (PMID:11266473)
GO_REF:0000107

PMID:11266473

GO_REF:0000107

NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829

Stx11

syntaxin 11

acts_upstream_of_or_within

ISO

MGI:5461477 (PMID:23042080), (PMID:23190531)

PMID:23042080 PMID:23190531

NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164

Unc13d

unc-13 homolog D

acts_upstream_of_or_within

ISO

MGI:3628822 (PMID:17420270)

PMID:17420270

NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687

Vamp2

vesicle-associated membrane protein 2

NOT|involved_in

ISO

(PMID:18042464)

PMID:18042464

NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809

Vamp7

vesicle-associated membrane protein 7

involved_in

ISO

(PMID:18042464)

PMID:18042464

NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097

natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07028902.1

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

Arl8b

ARF like GTPase 8B

involved_in

ISO
IEA
ISS

(PMID:24088571)
GO_REF:0000107
GO_REF:0000024

PMID:24088571

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596

Cd2

Cd2 molecule

involved_in

ISO
IEA

(PMID:23006327)
GO_REF:0000107

PMID:23006327

GO_REF:0000107

NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026

CD226 molecule

involved_in

ISO
IEA

(PMID:8673704)
GO_REF:0000107

PMID:8673704

GO_REF:0000107

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

Cebpg

CCAAT/enhancer binding protein gamma

involved_in

ISS
ISO

GO_REF:0000024
(PMID:10587348)

PMID:10587348

GO_REF:0000024

NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569

Fcgr3a

Fc gamma receptor 3A

involved_in

ISO

(PMID:10318937), (PMID:23006327)

PMID:10318937 PMID:23006327

NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921

Grb2

growth factor receptor bound protein 2

involved_in

ISO
IEA

(PMID:16582911)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Gzmb

granzyme B

involved_in

ISS
ISO

GO_REF:0000024
(PMID:21795594), (PMID:32188940)

PMID:21795594 PMID:32188940

GO_REF:0000024

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

Hcst

hematopoietic cell signal transducer

involved_in

ISO
IEA

(PMID:16582911)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:85,676,976...85,679,083
Ensembl chr 1:85,676,979...85,679,012

Il18

interleukin 18

acts_upstream_of_or_within

ISO
IEA

(PMID:15843532)
GO_REF:0000107

PMID:15843532

GO_REF:0000107

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Il21

interleukin 21

acts_upstream_of

ISO

(PMID:14764669)

PMID:14764669

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

Kif5b

kinesin family member 5B

involved_in

ISS
ISO

GO_REF:0000024
(PMID:24088571)

PMID:24088571

GO_REF:0000024

NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508

Kir3dl1

killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

involved_in

ISO

(PMID:18502829)

PMID:18502829

NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050

killer cell lectin like receptor E1

involved_in

ISO

(PMID:17562706)

PMID:17562706

NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638

killer cell lectin like receptor K1

involved_in

ISO

(PMID:17562706)

PMID:17562706

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

Lag3

lymphocyte activating 3

acts_upstream_of

ISO
IEA

MGI:2176269 (PMID:8602528)
GO_REF:0000107

PMID:8602528

GO_REF:0000107

NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404

Lyst

lysosomal trafficking regulator

involved_in

ISO
IEA

(PMID:10648412), (PMID:6154765)
GO_REF:0000107

PMID:6154765 PMID:10648412

GO_REF:0000107

NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480

Mill1

MHC I like leukocyte 1

involved_in

ISO

(PMID:10426993)

PMID:10426993

NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930

nectin cell adhesion molecule 2

involved_in

ISO
IEA

(PMID:15607800)
GO_REF:0000107

PMID:15607800

GO_REF:0000107

NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360

Nkg7

natural killer cell granule protein 7

involved_in

ISO

(PMID:32839608), (PMID:33911019)

PMID:32839608 PMID:33911019

NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983

Pik3cb

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

involved_in

ISO

(PMID:36248894)

PMID:36248894

NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:99,594,644...99,699,663

Pik3r1

phosphoinositide-3-kinase regulatory subunit 1

involved_in

ISO

(PMID:16582911)

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Plekhm2

pleckstrin homology and RUN domain containing M2

involved_in

ISO
IEA

(PMID:24088571)
GO_REF:0000107

PMID:24088571

GO_REF:0000107

NCBI chr 5:153,939,582...153,978,625
Ensembl chr 5:153,940,262...153,978,689

Prdx1

peroxiredoxin 1

acts_upstream_of_or_within

ISO

MGI:2670538 (PMID:12891360)

PMID:12891360

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

acts_upstream_of_or_within

ISO
IEA

MGI:1856073 (PMID:6971254)
GO_REF:0000107

PMID:6971254

GO_REF:0000107

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

PVR cell adhesion molecule

involved_in

ISO

(PMID:38289706)

PMID:38289706

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

Raet1e

retinoic acid early transcript 1E

involved_in

ISO

(PMID:15240696)

PMID:15240696

NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755

Rnf19b

ring finger protein 19B

acts_upstream_of_or_within

ISO
IEA

MGI:4436863 (PMID:19915045)
GO_REF:0000107

PMID:19915045

GO_REF:0000107

NCBI chr 5:146,690,453...146,715,729
Ensembl chr 5:141,406,118...141,431,380

Sh2d1a

SH2 domain containing 1A

acts_upstream_of

ISO
IEA

MGI:1349420|MGI:3575311|MGI:3622649 (PMID:16127454), (PMID:19648922)
GO_REF:0000107

PMID:16127454 PMID:19648922

GO_REF:0000107

NCBI chr X:121,373,693...121,401,923

Sh2d1b2

SH2 domain containing 1B2

acts_upstream_of

ISO
IEA

MGI:1328352|MGI:1349420|MGI:3641175 (PMID:16127454), (PMID:19648922)
GO_REF:0000107

PMID:16127454 PMID:19648922

GO_REF:0000107

NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509

Stat5a

signal transducer and activator of transcription 5A

acts_upstream_of

ISO
IEA

MGI:1857249 (PMID:9841920)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Stat5b

signal transducer and activator of transcription 5B

acts_upstream_of

ISO
IEA

MGI:2181592 (PMID:9841920)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Stx11

syntaxin 11

acts_upstream_of_or_within

ISO

MGI:5461477 (PMID:23042080)

PMID:23042080

NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164

Ulbp1

UL16 binding protein 1

involved_in

ISO

(PMID:11239445)

PMID:11239445

NCBI chr 1:1,694,255...1,716,160

Vav1

vav guanine nucleotide exchange factor 1

involved_in

ISO
IEA

(PMID:16582911)
GO_REF:0000107

GO_REF:0000107

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

natural killer cell mediated cytotoxicity directed against tumor cell target

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nkg7

natural killer cell granule protein 7

involved_in

ISO

(PMID:32839608)

PMID:32839608

NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983

natural killer cell mediated immunity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

killer cell lectin like receptor C2

involved_in

ISO

(PMID:18448674)

PMID:18448674

NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843

killer cell lectin like receptor D1

involved_in

ISO
IEA

(PMID:18448674)
GO_REF:0000107

PMID:18448674

GO_REF:0000107

NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518

Tyrobp

transmembrane immune signaling adaptor Tyrobp

involved_in

ISO
IEA

(PMID:9655483)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

negative regulation of AIM2 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Trim11

tripartite motif-containing 11

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:27498865)

PMID:27498865

GO_REF:0000024 GO_REF:0000107

NCBI chr10:44,255,019...44,270,711
Ensembl chr10:43,758,354...43,771,138

negative regulation of antibacterial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Spink5

serine peptidase inhibitor, Kazal type 5

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185

negative regulation of antifungal innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fam3a

FAM3 metabolism regulating signaling molecule A

involved_in

ISO
IEA

(PMID:18212107)
GO_REF:0000107

PMID:18212107

GO_REF:0000107

NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362

Usp15

ubiquitin specific peptidase 15

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:33093067)
GO_REF:0000024

PMID:33093067

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721

negative regulation of cGAS/STING signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aars2

alanyl-tRNA synthetase 2, mitochondrial

involved_in

ISO
ISS

(PMID:39322678)
GO_REF:0000024

PMID:39322678

GO_REF:0000024

NCBI chr 9:15,484,639...15,496,116
Ensembl chr 9:15,297,531...15,496,090

Akt1

AKT serine/threonine kinase 1

involved_in

IEA
ISO

GO_REF:0000107
(PMID:12172553), (PMID:26440888)

PMID:12172553 PMID:26440888

GO_REF:0000107

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

Aurkb

aurora kinase B

involved_in

IEA
ISO

GO_REF:0000107
(PMID:33542149)

PMID:33542149

GO_REF:0000107

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

Banf1

barrier to autointegration nuclear assembly factor 1

involved_in

ISO
IEA

(PMID:32792394)
GO_REF:0000107

PMID:32792394

GO_REF:0000107

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

cyclic GMP-AMP synthase

involved_in

ISO
IEA

(PMID:32911482), (PMID:32912999)
GO_REF:0000107

PMID:32911482 PMID:32912999

GO_REF:0000107

NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496

immunity-related GTPase M

involved_in

ISO

(PMID:32715615)

PMID:32715615

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

Lyplal1

lysophospholipase-like 1

involved_in

ISO

(PMID:37802025)

PMID:37802025

NCBI chr13:97,626,568...97,657,901
Ensembl chr13:97,626,451...97,657,867

Parp1

poly (ADP-ribose) polymerase 1

involved_in

ISO
IEA

(PMID:35460603)
GO_REF:0000107

PMID:35460603

GO_REF:0000107

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404

Pcbp2

poly(rC) binding protein 2

involved_in

ISO

(PMID:35322803)

PMID:35322803

NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863

Ppp6c

protein phosphatase 6, catalytic subunit

involved_in

ISO
IEA

(PMID:32474700)
GO_REF:0000107

PMID:32474700

GO_REF:0000107

NCBI chr 3:22,929,816...22,962,123
Ensembl chr 3:22,931,577...22,962,113

Prkdc

protein kinase, DNA-activated, catalytic subunit

involved_in

ISO

(PMID:33273464)

PMID:33273464

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:37890481)

PMID:37890481

GO_REF:0000024 GO_REF:0000107

NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567

Spsb3

splA/ryanodine receptor domain and SOCS box containing 3

involved_in

ISO

(PMID:38418882)

PMID:38418882

NCBI chr10:13,907,175...13,912,841
Ensembl chr10:13,907,253...13,912,841

three prime repair exonuclease 1

involved_in

ISO
IEA

(PMID:33476576)
GO_REF:0000107

PMID:33476576

GO_REF:0000107

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

Zdhhc18

zinc finger DHHC-type palmitoyltransferase 18

involved_in

IEA
ISO

GO_REF:0000107
(PMID:35438208)

PMID:35438208

GO_REF:0000107

NCBI chr 5:151,105,303...151,143,843
Ensembl chr 5:145,831,446...145,859,993

negative regulation of complement activation, alternative pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd46

CD46 molecule

involved_in

ISO

(PMID:9029106)

PMID:9029106

NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445

Susd4

sushi domain containing 4

involved_in

ISO

(PMID:23482636)

PMID:23482636

NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750

Vsig4

V-set and immunoglobulin domain containing 4

involved_in

ISO
IBA

UniProtKB:P01024 (PMID:17051150)
GO_REF:0000033

PMID:17051150

GO_REF:0000033

NCBI chr X:61,144,926...61,170,212
Ensembl chr X:61,144,928...61,170,212

negative regulation of complement activation, lectin pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

A2m

alpha-2-macroglobulin

involved_in

ISO

(PMID:12538697)

PMID:12538697

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

Serping1

serpin family G member 1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:10946292)

PMID:10946292

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Itch

itchy E3 ubiquitin protein ligase

involved_in

ISO
IEA

(PMID:27736772)
GO_REF:0000107

PMID:27736772

GO_REF:0000107

NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:143,645,637...143,733,543

Marchf5

membrane associated ring-CH-type finger 5

involved_in

IEA
ISO

GO_REF:0000107
(PMID:31881323)

PMID:31881323

GO_REF:0000107

NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632

Rnf39

ring finger protein 39

involved_in

ISO

(PMID:33674311)

PMID:33674311

NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,604,794...1,610,283

Sec14l1

SEC14-like lipid binding 1

involved_in

IEA
ISO

GO_REF:0000107
(PMID:23843640)

PMID:23843640

GO_REF:0000107

NCBI chr10:102,319,920...102,367,070
Ensembl chr10:102,319,920...102,367,068

Tarbp2

Tarbp2 subunit of RISC loading complex

involved_in

ISO
IEA

(PMID:30927622)
GO_REF:0000107

PMID:30927622

GO_REF:0000107

NCBI chr 7:135,527,710...135,532,826
Ensembl chr 7:133,649,090...133,654,314

Tax1bp1

Tax1 binding protein 1

involved_in

ISO
IEA

(PMID:27736772)
GO_REF:0000107

PMID:27736772

GO_REF:0000107

NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100

Tspan6

tetraspanin 6

involved_in

ISO
IEA

(PMID:22908223)
GO_REF:0000107

PMID:22908223

GO_REF:0000107

NCBI chr X:97,092,394...97,099,659
Ensembl chr X:97,092,388...97,099,309

negative regulation of innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aconitate decarboxylase 1

involved_in

ISO

(PMID:23609450)

NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529

Atg12

autophagy related 12

involved_in

ISO

(PMID:17709747)

PMID:17709747

NCBI chr18:41,638,841...41,649,311
Ensembl chr18:39,452,191...39,462,418

Atg5

autophagy related 5

involved_in

IEA
ISO

GO_REF:0000107
(PMID:17709747)

PMID:17709747

GO_REF:0000107

NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209

Aurkb

aurora kinase B

involved_in

ISO
IEA

(PMID:33542149)
GO_REF:0000107

PMID:33542149

GO_REF:0000107

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

Banf1

barrier to autointegration nuclear assembly factor 1

involved_in

ISO
IEA

(PMID:32792394)
GO_REF:0000107

PMID:32792394

GO_REF:0000107

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

Cactin

cactin, spliceosome C complex subunit

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829

Ccr1

C-C motif chemokine receptor 1

involved_in

ISO

(PMID:15557190)

PMID:15557190

NCBI chr 8:123,556,286...123,561,841

Cep63

centrosomal protein 63

involved_in

ISO
IEA

(PMID:35793002)
GO_REF:0000107

PMID:35793002

GO_REF:0000107

NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177

Ddx39a

DExD-box helicase 39A

involved_in

ISO
IEA

(PMID:32393512)
GO_REF:0000107

PMID:32393512

GO_REF:0000107

NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954

DEXH-box helicase 58

involved_in

ISO
IEA

(PMID:21525357)
GO_REF:0000107

PMID:21525357

GO_REF:0000107

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Drd2

dopamine receptor D2

involved_in

ISO
IEA

(PMID:23242137)
GO_REF:0000107

PMID:23242137

GO_REF:0000107

NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875

Dtx4

deltex E3 ubiquitin ligase 4

involved_in

ISO

(PMID:27692986), (PMID:35793002)

PMID:27692986 PMID:35793002

NCBI chr 1:218,882,391...218,969,837
Ensembl chr 1:209,460,735...209,492,818

Grn

granulin precursor

involved_in

ISS
ISO

GO_REF:0000024
(PMID:20026663)

PMID:20026663

GO_REF:0000024

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

hepatitis A virus cellular receptor 2

involved_in

ISO

(PMID:22842346)

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

Irak3

interleukin-1 receptor-associated kinase 3

involved_in

ISO
IEA

(PMID:12150927)
GO_REF:0000107

PMID:12150927

GO_REF:0000107

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

Lyar

Ly1 antibody reactive

involved_in

IEA
ISO

GO_REF:0000107
(PMID:31413131)

PMID:31413131

GO_REF:0000107

NCBI chr14:72,576,878...72,590,854
Ensembl chr14:72,576,879...72,590,612

Mir181b1

microRNA 181b-1

involved_in

ISO

ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240)

PMID:25505240

NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797

Mir181b2

microRNA 181b-2

involved_in

ISO

ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240)

PMID:25505240

NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035

Mir21

microRNA 21

involved_in

ISO

(PMID:22286305)

PMID:22286305

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

Mul1

mitochondrial E3 ubiquitin protein ligase 1

involved_in

ISO
IEA

(PMID:23399697)
GO_REF:0000107

PMID:23399697

GO_REF:0000107

NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:150,652,812...150,661,863

Nlrc3

NLR family, CARD domain containing 3

involved_in

ISO

(PMID:24560620)

PMID:24560620

NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398

Nlrp4

NLR family, pyrin domain containing 4

involved_in

ISO

(PMID:27692986)

PMID:27692986

NCBI chr 1:68,089,321...68,132,429
Ensembl chr 1:68,089,321...68,127,521

Nlrx1

NLR family member X1

acts_upstream_of_or_within

ISO
IEA

MGI:5141085 (PMID:21703540)
GO_REF:0000107

PMID:21703540

GO_REF:0000107

NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484

N-myc (and STAT) interactor

involved_in
acts_upstream_of_or_within

ISO

(PMID:26342464)
(PMID:23956435)

PMID:23956435 PMID:26342464

NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498

Parp1

poly (ADP-ribose) polymerase 1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:35460603)
(PMID:32844745), (PMID:35460603)

PMID:32844745 PMID:35460603

GO_REF:0000024 GO_REF:0000107

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404

Pim1

Pim-1 proto-oncogene, serine/threonine kinase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:37797010)

PMID:37797010

GO_REF:0000024 GO_REF:0000107

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

involved_in

ISO
IEA

(PMID:34811497)
GO_REF:0000107

PMID:34811497

GO_REF:0000107

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Sfn

stratifin

involved_in

ISO

(PMID:37797010)

PMID:37797010

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

TNF alpha induced protein 3

involved_in

ISO
IEA

(PMID:23609450)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

Trafd1

TRAF type zinc finger domain containing 1

involved_in

ISS
ISO
IBA

GO_REF:0000024
(PMID:18849341)
GO_REF:0000033

PMID:18849341

GO_REF:0000024 GO_REF:0000033

NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525

three prime repair exonuclease 1

involved_in

ISO
IEA

(PMID:33476576)
GO_REF:0000107

PMID:33476576

GO_REF:0000107

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

tripartite motif-containing 21

involved_in

ISO
IEA

(PMID:26342464)
GO_REF:0000107

PMID:26342464

GO_REF:0000107

NCBI chr 1:166,376,829...166,399,441
Ensembl chr 1:156,964,913...156,987,440

Tyro3

TYRO3 protein tyrosine kinase

involved_in

ISS
ISO
IEA

GO_REF:0000024
UniProtKB:Q00993|UniProtKB:Q60805 (PMID:18083102)
GO_REF:0000107

PMID:18083102

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142

Usp38

ubiquitin specific peptidase 38

involved_in

ISO
IEA

(PMID:27692986)
GO_REF:0000107

PMID:27692986

GO_REF:0000107

NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437

Ywhaz

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

involved_in

ISO
IEA

(PMID:35662396)
GO_REF:0000107

PMID:35662396

GO_REF:0000107

NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668

Zdhhc18

zinc finger DHHC-type palmitoyltransferase 18

involved_in

ISO
IEA
ISS

(PMID:35438208)
GO_REF:0000107
GO_REF:0000024

PMID:35438208

GO_REF:0000024 GO_REF:0000107

NCBI chr 5:151,105,303...151,143,843
Ensembl chr 5:145,831,446...145,859,993

negative regulation of MDA-5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C1qbp

complement C1q binding protein

involved_in

ISO
IEA
ISS

(PMID:19164550)
GO_REF:0000107
GO_REF:0000024

PMID:19164550

GO_REF:0000024 GO_REF:0000107

NCBI chr10:56,198,534...56,203,185
Ensembl chr10:55,699,954...55,704,649

DEXH-box helicase 58

involved_in

ISO
IEA

(PMID:21187438)
GO_REF:0000107

PMID:21187438

GO_REF:0000107

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Riok3

RIO kinase 3

involved_in

ISO
IEA

(PMID:25865883)
GO_REF:0000107

PMID:25865883

GO_REF:0000107

NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343

Tkfc

triokinase and FMN cyclase

involved_in

ISS
ISO

GO_REF:0000024
(PMID:17600090)

PMID:17600090

GO_REF:0000024

NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737

negative regulation of MyD88-dependent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd300a

Cd300a molecule

involved_in

ISO

(PMID:22043923)

PMID:22043923

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

Cd300lf

Cd300 molecule-like family member F

involved_in

ISS
ISO

GO_REF:0000024
(PMID:22043923)

PMID:22043923

GO_REF:0000024

NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041

negative regulation of MyD88-independent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Sarm1

sterile alpha and TIR motif containing 1

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822

negative regulation of natural killer cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd96

CD96 molecule

acts_upstream_of_or_within

ISO

MGI:5617136 (PMID:24658051)

PMID:24658051

NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621

RT1 class I, locus CE5

involved_in

ISO

(PMID:24018270)

PMID:24018270

NCBI chr20:3,403,418...3,479,476

negative regulation of natural killer cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

galectin 9

involved_in

ISO

(PMID:23408620)

PMID:23408620

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

RT1 class I, locus CE5

involved_in

ISO

(PMID:24018270)

PMID:24018270

NCBI chr20:3,403,418...3,479,476

negative regulation of natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arrb2

arrestin, beta 2

involved_in

ISO

(PMID:18604210)

PMID:18604210

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

Clec12b

C-type lectin domain family 12, member B

involved_in

ISO

(PMID:17562706)

PMID:17562706

NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946

Crk

CRK proto-oncogene, adaptor protein

IMP

RGD

PMID:18835194

RGD:11568650

NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406

Gfer

growth factor, augmenter of liver regeneration

IDA

RGD

PMID:9021955

RGD:9685777

NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869

Grb2

growth factor receptor bound protein 2

involved_in

ISO
IEA

(PMID:25870599)
GO_REF:0000107

PMID:25870599

GO_REF:0000107

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Igf2

insulin-like growth factor 2

IDA

RGD

PMID:9021955

RGD:9685777

NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018

Inpp5d

inositol polyphosphate-5-phosphatase D

involved_in

ISO
IEA

(PMID:23154388)
GO_REF:0000107

PMID:23154388

GO_REF:0000107

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Klrc1

killer cell lectin like receptor C1

involved_in

ISO

(PMID:9485206), (PMID:9486650)

PMID:9485206 PMID:9486650

NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425

killer cell lectin like receptor D1

involved_in

ISO
IEA
ISS

(PMID:9486650)
GO_REF:0000107
GO_REF:0000024

PMID:9486650

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518

galectin 9

involved_in

ISO

(PMID:23408620)

PMID:23408620

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

Mill1

MHC I like leukocyte 1

involved_in

ISO

(PMID:20068167)

PMID:20068167

NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930

nectin cell adhesion molecule 2

involved_in

ISO
IEA

(PMID:28515320)
GO_REF:0000107

PMID:28515320

GO_REF:0000107

NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360

Nectin4

nectin cell adhesion molecule 4

involved_in

ISO
IEA

(PMID:32503945)
GO_REF:0000107

PMID:32503945

GO_REF:0000107

NCBI chr13:83,802,589...83,821,711
Ensembl chr13:83,803,184...83,821,709

PVR cell adhesion molecule

involved_in

ISO

(PMID:23154388)

PMID:23154388

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

RT1-A1

RT1 class Ia, locus A1

IMP

RGD

PMID:10837412

RGD:2313500

NCBI chr20:4,905,309...4,914,593

RT1 class Ia, locus A2

involved_in

ISO

(PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650)

PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510

NCBI chr20:4,870,939...4,910,183

RT1 class I, locus CE5

involved_in

ISO

(PMID:24018270)

PMID:24018270

NCBI chr20:3,403,418...3,479,476

RT1 class Ib, locus M3, gene 1

involved_in

ISO

(PMID:10190900), (PMID:12874224)

PMID:10190900 PMID:12874224

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

Sh2d1b2

SH2 domain containing 1B2

acts_upstream_of_or_within

ISO
IEA

MGI:3641175 (PMID:16127454)
GO_REF:0000107

PMID:16127454

GO_REF:0000107

NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509

Tigit

T cell immunoreceptor with Ig and ITIM domains

involved_in

ISO
IEA

(PMID:23154388)
GO_REF:0000107

PMID:23154388

GO_REF:0000107

NCBI chr11:57,029,024...57,046,627
Ensembl chr11:57,029,118...57,045,994

negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ceacam1

CEA cell adhesion molecule 1

involved_in

ISO
ISS

(PMID:23696226)
GO_REF:0000024

PMID:23696226

GO_REF:0000024

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

hepatitis A virus cellular receptor 2

involved_in

ISO

(PMID:22842346)

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

killer cell lectin like receptor E1

IDA

RGD

PMID:12782717

RGD:1299590

NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638

Tgfb1

transforming growth factor, beta 1

involved_in

ISO
IEA

(PMID:24586048)
GO_REF:0000107

PMID:24586048

GO_REF:0000107

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

negative regulation of NLRP3 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abhd17a

abhydrolase domain containing 17A, depalmitoylase

involved_in

ISO
IEA

(PMID:38092000)
GO_REF:0000107

PMID:38092000

GO_REF:0000107

NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762

Abhd8

abhydrolase domain containing 8

involved_in

IEA
ISO

GO_REF:0000107
(PMID:39225180)

PMID:39225180

GO_REF:0000107

NCBI chr16:18,178,441...18,185,178
Ensembl chr16:18,144,464...18,157,667

Cptp

ceramide-1-phosphate transfer protein

involved_in

ISO
ISS

(PMID:29164996)
GO_REF:0000024

PMID:29164996

GO_REF:0000024

NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017

Csnk1a1

casein kinase 1, alpha 1

involved_in

ISS
ISO

GO_REF:0000024
(PMID:34615873)

PMID:34615873

GO_REF:0000024

NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271

Fbxl2

F-box and leucine-rich repeat protein 2

involved_in

ISO
IEA

(PMID:26037928)
GO_REF:0000107

PMID:26037928

GO_REF:0000107

NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066

Hspa8

heat shock protein family A (Hsp70) member 8

involved_in

ISO

(PMID:36586411)

PMID:36586411

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

immunity-related GTPase M

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:30612879)

PMID:30612879

GO_REF:0000024 GO_REF:0000107

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

Lamp2

lysosomal-associated membrane protein 2

involved_in

ISO

(PMID:36586411)

PMID:36586411

NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522

Mefv

MEFV innate immunity regulator, pyrin

involved_in

ISS
ISO

GO_REF:0000024
(PMID:26347139)

PMID:26347139

GO_REF:0000024

NCBI chr10:12,288,514...12,303,337
Ensembl chr10:11,787,422...11,796,973

Nlrc3

NLR family, CARD domain containing 3

involved_in

ISO
IEA

(PMID:25277106)
GO_REF:0000107

PMID:25277106

GO_REF:0000107

NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398

Sirt2

sirtuin 2

acts_upstream_of_or_within

ISO
IEA

(PMID:23502856)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:84,052,903...84,076,975

triggering receptor expressed on myeloid cells 2

acts_upstream_of_or_within

ISO
IEA

(PMID:32514138)
GO_REF:0000107
(PMID:29887864)

PMID:29887864 PMID:32514138

GO_REF:0000107

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

tripartite motif-containing 31

involved_in

ISO
IEA

(PMID:27929086)
GO_REF:0000107

PMID:27929086

GO_REF:0000107

NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494

tripartite motif-containing 65

involved_in

IEA
ISO

GO_REF:0000107
(PMID:34512673)

PMID:34512673

GO_REF:0000107

NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971

Zdhhc12

zinc finger DHHC-type palmitoyltransferase 12

involved_in

ISS
ISO

GO_REF:0000024
(PMID:36586411)

PMID:36586411

GO_REF:0000024

NCBI chr 3:33,761,338...33,764,207
Ensembl chr 3:13,363,504...13,366,474

negative regulation of non-canonical inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:37962578)

PMID:37962578

GO_REF:0000024 GO_REF:0000107

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TNF alpha induced protein 3

involved_in

ISO
IEA

(PMID:18342009)
GO_REF:0000107

PMID:18342009

GO_REF:0000107

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Erbin

erbb2 interacting protein

involved_in

ISO
IEA

(PMID:16203728)
GO_REF:0000107

PMID:16203728

GO_REF:0000107

NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852

protein tyrosine phosphatase, non-receptor type 22

involved_in

ISO

(PMID:23991106)

PMID:23991106

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

TNF alpha induced protein 3

involved_in

ISO
IEA

(PMID:18342009)
GO_REF:0000107

PMID:18342009

GO_REF:0000107

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

Znrf4

zinc and ring finger 4

involved_in

ISO

(PMID:28656966)

PMID:28656966

NCBI chr 9:1,440,444...1,441,632
Ensembl chr 9:1,353,306...1,354,584

negative regulation of respiratory burst involved in inflammatory response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dusp10

dual specificity phosphatase 10

acts_upstream_of_or_within

ISO
IEA

MGI:3052343 (PMID:19696743)
GO_REF:0000107

PMID:19696743

GO_REF:0000107

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716

Grn

granulin precursor

involved_in

ISS
ISO

GO_REF:0000024
(PMID:12526812)

PMID:12526812

GO_REF:0000024

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

Ins2

insulin 2

involved_in

ISO

(PMID:11443198)

PMID:11443198

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

Rps19

ribosomal protein S19

involved_in

ISO

(PMID:15750715)

PMID:15750715

NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508

Slamf8

SLAM family member 8

acts_upstream_of_or_within

ISO

MGI:5442794 (PMID:25799045)

PMID:25799045

NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211

negative regulation of RIG-I signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C1qbp

complement C1q binding protein

involved_in

ISO
IEA
ISS

(PMID:19164550)
GO_REF:0000107
GO_REF:0000024

PMID:19164550

GO_REF:0000024 GO_REF:0000107

NCBI chr10:56,198,534...56,203,185
Ensembl chr10:55,699,954...55,704,649

DEXH-box helicase 58

involved_in

ISO
IEA
IBA

(PMID:18411269), (PMID:21187438)
GO_REF:0000107
(PMID:17475874)
GO_REF:0000033

PMID:17475874 PMID:18411269 PMID:21187438

GO_REF:0000033 GO_REF:0000107

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Gpatch3

G patch domain containing 3

involved_in

ISO
IEA
IBA

(PMID:28414768)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033

RGD
InterPro
Ensembl
GO_Central

PMID:28414768

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr 5:145,800,107...145,809,519
Ensembl chr 5:145,800,111...145,809,250

Nlrx1

NLR family member X1

acts_upstream_of_or_within

ISO
IEA

MGI:5141085 (PMID:21703540)
GO_REF:0000107

PMID:21703540

GO_REF:0000107

NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484

Nploc4

NPL4 homolog, ubiquitin recognition factor

involved_in

ISO
IEA
ISS

(PMID:26471729)
GO_REF:0000107
GO_REF:0000024

PMID:26471729

GO_REF:0000024 GO_REF:0000107

NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913

Rnf125

ring finger protein 125

involved_in

ISO
IEA

(PMID:17460044), (PMID:26471729)
GO_REF:0000107

PMID:17460044 PMID:26471729

GO_REF:0000107

NCBI chr18:12,528,995...12,550,646
Ensembl chr18:12,253,852...12,275,983

Sec14l1

SEC14-like lipid binding 1

involved_in

ISO
IEA
IBA

(PMID:23843640)
GO_REF:0000107
GO_REF:0000033

PMID:23843640

GO_REF:0000033 GO_REF:0000107

NCBI chr10:102,319,920...102,367,070
Ensembl chr10:102,319,920...102,367,068

Ufd1

ubiquitin recognition factor in ER associated degradation 1

involved_in

ISO
IEA
ISS

(PMID:26471729)
GO_REF:0000107
GO_REF:0000024

PMID:26471729

GO_REF:0000024 GO_REF:0000107

NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087

negative regulation of toll-like receptor 2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aconitate decarboxylase 1

involved_in

ISO

(PMID:23609450)

NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529

LYN proto-oncogene, Src family tyrosine kinase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:20385881)

PMID:20385881

GO_REF:0000024 GO_REF:0000107

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

multifunctional ROCO family signaling regulator 1

involved_in

ISO
IEA

(PMID:26599367)
GO_REF:0000107

PMID:26599367

GO_REF:0000107

NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

ISO

MGI:2680581 (PMID:15220916)

PMID:15220916

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

toll-like receptor 6

involved_in

ISO
IEA

ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949)
GO_REF:0000107

PMID:22198949

GO_REF:0000107

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

triggering receptor expressed on myeloid cells 2

involved_in

ISO

(PMID:31134514)

PMID:31134514

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

negative regulation of toll-like receptor 3 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2R like trypsin receptor 1

involved_in

ISO
IEA

(PMID:19865078)
GO_REF:0000107

PMID:19865078

GO_REF:0000107

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

TNF alpha induced protein 3

involved_in

ISO
IEA

(PMID:15474016)
GO_REF:0000107

PMID:15474016

GO_REF:0000107

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

Ubqln1

ubiquilin 1

involved_in

IEA
ISO

GO_REF:0000107
(PMID:21695056)

PMID:21695056

GO_REF:0000107

NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090

negative regulation of toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aconitate decarboxylase 1

involved_in

ISO

(PMID:23609450)

NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529

Bpifb1

BPI fold containing family B, member 1

involved_in

ISO
IBA
IEA

(PMID:21900486)
GO_REF:0000033
GO_REF:0000107

PMID:21900486

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256

Dab2ip

DAB2 interacting protein

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:19948740)

PMID:19948740

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280

LYN proto-oncogene, Src family tyrosine kinase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:20385881)

PMID:20385881

GO_REF:0000024 GO_REF:0000107

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

multifunctional ROCO family signaling regulator 1

involved_in

ISO
IEA

(PMID:28609714)
GO_REF:0000107

PMID:28609714

GO_REF:0000107

NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743

Mir140

microRNA 140

involved_in

ISO

UniProtKB:O00206 (PMID:30233718), (PMID:30321456)

PMID:30233718 PMID:30321456

NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675

Mir200b

microRNA 200b

involved_in

ISO

(PMID:22522429)

PMID:22522429

NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366

Mir200c

microRNA 200c

involved_in

ISO

(PMID:22522429)

PMID:22522429

NCBI chr 4:157,523,679...157,523,747

Mir20a

microRNA 20a

involved_in

ISO

(PMID:29653364)

PMID:29653364

NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168

Mir708

microRNA 708

involved_in

ISO

(PMID:31599428)

PMID:31599428

NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963

Nr1d1

nuclear receptor subfamily 1, group D, member 1

involved_in

ISO
IEA

(PMID:18511497)
GO_REF:0000107

PMID:18511497

GO_REF:0000107

NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705

Rab7b

Rab7b, member RAS oncogene family

involved_in

ISO
IEA

(PMID:17395780)
GO_REF:0000107

PMID:17395780

GO_REF:0000107

NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581

Sqstm1

sequestosome 1

involved_in

ISO
IEA

(PMID:31281713)
GO_REF:0000107

PMID:31281713

GO_REF:0000107

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

Tax1bp1

Tax1 binding protein 1

involved_in

ISO
IEA

(PMID:28898289)
GO_REF:0000107

PMID:28898289

GO_REF:0000107

NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100

TIR domain containing adaptor molecule 2

involved_in

ISO

(PMID:19412184)

PMID:19412184

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

triggering receptor expressed on myeloid cells 2

involved_in

ISO

(PMID:29407460), (PMID:31134514)

PMID:29407460 PMID:31134514

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

Trim32

tripartite motif-containing 32

involved_in

ISO

(PMID:28898289)

PMID:28898289

NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:78,999,389...79,022,018

negative regulation of toll-like receptor 5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TNF alpha induced protein 3

involved_in

ISO
IEA

(PMID:19912257)
GO_REF:0000107

PMID:19912257

GO_REF:0000107

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

negative regulation of toll-like receptor 6 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mir210

microRNA 210

involved_in

ISO

(PMID:38742642)

PMID:38742642

NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454

negative regulation of toll-like receptor 9 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gramd4

GRAM domain containing 4

involved_in

IBA
ISO

GO_REF:0000033
(PMID:25917084)

PMID:25917084

GO_REF:0000033

NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053

Ppt1

palmitoyl-protein thioesterase 1

involved_in

ISO
IEA

(PMID:14716310)
GO_REF:0000107

PMID:14716310

GO_REF:0000107

NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048

Ptprs

protein tyrosine phosphatase, receptor type, S

involved_in

ISO

(PMID:26231120)

PMID:26231120

NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947

Rab7b

Rab7b, member RAS oncogene family

involved_in

ISO
IEA

(PMID:19587007)
GO_REF:0000107

PMID:19587007

GO_REF:0000107

NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581

negative regulation of toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arrb2

arrestin, beta 2

involved_in

ISO

(PMID:16378096)

PMID:16378096

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

Cactin

cactin, spliceosome C complex subunit

involved_in

ISO
IEA

(PMID:20829348)
GO_REF:0000107

UniProt
GO_Central
RGD
Ensembl

PMID:20829348

GO_REF:0000107

NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829

Gpr108

G protein-coupled receptor 108

involved_in

ISS
IBA
ISO
IEA

GO_REF:0000024
GO_REF:0000033
(PMID:30332431)
GO_REF:0000107

PMID:30332431

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr 9:2,120,740...2,131,771
Ensembl chr 9:2,120,744...2,132,572

Gps2

G protein pathway suppressor 2

involved_in

ISO

(PMID:28039360)

PMID:28039360

NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650

Irak3

interleukin-1 receptor-associated kinase 3

involved_in

ISO
IEA

(PMID:12150927)
GO_REF:0000107

PMID:12150927

GO_REF:0000107

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

Irf4

interferon regulatory factor 4

acts_upstream_of_or_within

ISO
IEA

MGI:2387941 (PMID:16236719)
GO_REF:0000107

PMID:16236719

GO_REF:0000107

NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070

Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:23589304)

RGD
GO_Central
Ensembl
UniProt

PMID:23589304

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899

Lrrc14

leucine rich repeat containing 14

involved_in

ISO
IBA
IEA
ISS

(PMID:27426725)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024

PMID:27426725

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr 7:108,430,755...108,437,118
Ensembl chr 7:108,430,792...108,437,111

Mir140

microRNA 140

IMP

RGD

PMID:31376096

RGD:329337378

NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675

Mir17

microRNA 17

involved_in

ISO

(PMID:26041742)

PMID:26041742

NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712

Mir19a

microRNA 19a

involved_in

ISO

(PMID:26041742)

RGD
Ensembl
GO_Central
UniProt

PMID:26041742

NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993

Nfkbil1

NFKB inhibitor like 1

involved_in

ISO
IEA
IBA
ISS

(PMID:20829348)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024

PMID:20829348

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616

NLR family, pyrin domain containing 6

acts_upstream_of_or_within

ISO
IEA

MGI:5085850 (PMID:22763455)
GO_REF:0000107

PMID:22763455

GO_REF:0000107

NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113

Otud4

OTU deubiquitinase 4

involved_in

ISO
IBA

(PMID:29395066)
GO_REF:0000033

PMID:29395066

GO_REF:0000033

NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815

Pdpk1

3-phosphoinositide dependent protein kinase-1

involved_in

IEA
ISO

GO_REF:0000107
(PMID:20584979)

PMID:20584979

GO_REF:0000107

NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623

phosphoinositide-3-kinase adaptor protein 1

involved_in

ISO

(PMID:20728433)

PMID:20728433

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

Ptgs2os

prostaglandin-endoperoxide synthase 2, opposite strand

acts_upstream_of_or_within

ISO

(PMID:23907535)

PMID:23907535

NCBI chr13:62,160,002...62,163,710

Rnf115

ring finger protein 115

involved_in

ISO
IEA

(PMID:35343654)
GO_REF:0000107

PMID:35343654

GO_REF:0000107

NCBI chr 2:186,950,959...187,018,673
Ensembl chr 2:184,262,371...184,329,823

Smpdl3b

sphingomyelin phosphodiesterase, acid-like 3B

involved_in

ISO
IEA

(PMID:26095358)
GO_REF:0000107

PMID:26095358

GO_REF:0000107

NCBI chr 5:144,944,618...144,966,703
Ensembl chr 5:144,944,636...144,966,720

Tyro3

TYRO3 protein tyrosine kinase

involved_in

ISS
ISO
IEA

GO_REF:0000024
UniProtKB:Q00993|UniProtKB:Q60805 (PMID:18083102)
GO_REF:0000107

PMID:18083102

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142

Ywhae

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

involved_in

ISO

(PMID:35343654)

PMID:35343654

NCBI chr10:61,082,934...61,120,618
Ensembl chr10:60,584,652...60,671,589

negative regulation of type I interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adar

adenosine deaminase, RNA-specific

acts_upstream_of_or_within

ISO
IEA

MGI:3828307 (PMID:19060901)
GO_REF:0000107

PMID:19060901

GO_REF:0000107

NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282

Cactin

cactin, spliceosome C complex subunit

involved_in

ISO
IEA

(PMID:20829348)
GO_REF:0000107

PMID:20829348

GO_REF:0000107

NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829

Cnot7

CCR4-NOT transcription complex, subunit 7

involved_in

ISO
IEA

(PMID:23386060)
GO_REF:0000107

PMID:23386060

GO_REF:0000107

NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576

Dcst1

DC-STAMP domain containing 1

involved_in

ISO
IEA

(PMID:27782195)
GO_REF:0000107

PMID:27782195

GO_REF:0000107

NCBI chr 2:177,063,083...177,079,914
Ensembl chr 2:174,765,350...174,781,806

Eif4e2

eukaryotic translation initiation factor 4E family member 2

involved_in

ISO
IEA

(PMID:35878012)
GO_REF:0000107

PMID:35878012

GO_REF:0000107

NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482

Gigyf2

GRB10 interacting GYF protein 2

involved_in

ISO
IEA

(PMID:35878012)
GO_REF:0000107

PMID:35878012

GO_REF:0000107

NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715

Isg15

ISG15 ubiquitin-like modifier

involved_in

ISO
IEA

(PMID:28724761)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

Mettl3

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

involved_in

ISO
IEA

(PMID:30559377)
GO_REF:0000107

PMID:30559377

GO_REF:0000107

NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041

Mir21

microRNA 21

involved_in

ISO

(PMID:23633945)

PMID:23633945

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

Mmp12

matrix metallopeptidase 12

involved_in

IEA
ISO

GO_REF:0000107
(PMID:24784232)

PMID:24784232

GO_REF:0000107

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

Mul1

mitochondrial E3 ubiquitin protein ligase 1

involved_in

ISO
IEA

(PMID:23399697)
GO_REF:0000107

PMID:23399697

GO_REF:0000107

NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:150,652,812...150,661,863

NLR family, CARD domain containing 5

involved_in

ISO
IBA

(PMID:20434986)
GO_REF:0000033

PMID:20434986

GO_REF:0000033

NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121

2'-5' oligoadenylate synthetase 1A

involved_in

ISO

(PMID:30078389)

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

2'-5'-oligoadenylate synthetase 3

involved_in

ISO
IEA

(PMID:30078389)
GO_REF:0000107

GO_REF:0000107

NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781

Ptpn2

protein tyrosine phosphatase, non-receptor type 2

involved_in

ISO
IEA
ISS

(PMID:11909529)
(PMID:11909529), (PMID:12138178)
GO_REF:0000107
GO_REF:0000024

PMID:11909529 PMID:12138178

GO_REF:0000024 GO_REF:0000107

NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627

Samhd1

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

involved_in

ISO
IEA

(PMID:29670289)
GO_REF:0000107
(PMID:23972988)

PMID:23972988 PMID:29670289

GO_REF:0000107

NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386

Smim30

small integral membrane protein 30

involved_in

ISO

(PMID:37656786)

PMID:37656786

NCBI chr X:34,443,180...34,443,365

Stat2

signal transducer and activator of transcription 2

involved_in

ISO
IEA

(PMID:28165510)
GO_REF:0000107

PMID:28165510

GO_REF:0000107

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

three prime repair exonuclease 1

acts_upstream_of_or_within

ISO
IEA

MGI:3052754 (PMID:18724932)
GO_REF:0000107

PMID:18724932

GO_REF:0000107

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

Ttll12

tubulin tyrosine ligase like 12

involved_in

ISO
IEA

(PMID:28011935)
GO_REF:0000107

PMID:28011935

GO_REF:0000107

NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356

Usp18

ubiquitin specific peptidase 18

involved_in

ISO

(PMID:28165510)

PMID:28165510

NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144

Ythdf2

YTH N6-methyladenosine RNA binding protein F2

involved_in

ISO
IEA

(PMID:30559377)
GO_REF:0000107

PMID:30559377

GO_REF:0000107

NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144

Ythdf3

YTH N6-methyladenosine RNA binding protein F3

involved_in

ISO
IEA

(PMID:30591559)
GO_REF:0000107

PMID:30591559

GO_REF:0000107

NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606

negative regulation of type II interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arg1

arginase 1

involved_in

ISO
IEA

(PMID:16709924)
GO_REF:0000107

PMID:16709924

GO_REF:0000107

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

Dnaja3

DnaJ heat shock protein family (Hsp40) member A3

involved_in

ISO

(PMID:11679576)

PMID:11679576

NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161

Otop1

otopetrin 1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:24379350)

PMID:24379350

GO_REF:0000024 GO_REF:0000107

NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497

Parp14

poly (ADP-ribose) polymerase family, member 14

involved_in

ISO
IEA
IBA

(PMID:27796300)
GO_REF:0000107
GO_REF:0000033

PMID:27796300

GO_REF:0000033 GO_REF:0000107

NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916

Pparg

peroxisome proliferator-activated receptor gamma

involved_in

ISO

(PMID:21268089)

PMID:21268089

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

Ptpn2

protein tyrosine phosphatase, non-receptor type 2

involved_in
NOT|involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:12138178)
GO_REF:0000107

PMID:12138178

GO_REF:0000024 GO_REF:0000107

NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627

neutrophil-mediated killing of bacterium

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MYD88, innate immune signal transduction adaptor

acts_upstream_of_or_within

ISO
IEA

MGI:104696 (PMID:22419116)
GO_REF:0000107

PMID:22419116

GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

Pcyox1l

prenylcysteine oxidase 1 like

involved_in

ISO
IEA

(PMID:37179332)
GO_REF:0000107

PMID:37179332

GO_REF:0000107

NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327

Scnn1b

sodium channel epithelial 1 subunit beta

acts_upstream_of_or_within

ISO

MGI:108005 (PMID:22419116)

PMID:22419116

NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451

neutrophil-mediated killing of fungus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Elane

elastase, neutrophil expressed

acts_upstream_of_or_within

ISO
IEA

MGI:2182177 (PMID:11907569)
GO_REF:0000107

GO_REF:0000107

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

Ncf1

neutrophil cytosolic factor 1

acts_upstream_of_or_within

ISO
IEA

MGI:3576788 (PMID:11907569)
GO_REF:0000107

GO_REF:0000107

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

neutrophil-mediated killing of gram-negative bacterium

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dao

D-amino-acid oxidase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:25425233)

PMID:25425233

GO_REF:0000024 GO_REF:0000107

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

Elane

elastase, neutrophil expressed

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

coagulation factor II, thrombin

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

Trem1

triggering receptor expressed on myeloid cells 1

involved_in
acts_upstream_of_or_within

IBA
ISO

GO_REF:0000033
MGI:1930003 (PMID:23241959)

PMID:23241959

GO_REF:0000033

NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203

Trem3

triggering receptor expressed on myeloid cells 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 9:12,749,821...12,762,547
Ensembl chr 9:12,749,852...12,760,779

Tusc2

tumor suppressor 2, mitochondrial calcium regulator

acts_upstream_of_or_within

ISO
IEA

MGI:3706236 (PMID:24042119)
GO_REF:0000107

PMID:24042119

GO_REF:0000107

NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056

neutrophil-mediated killing of gram-positive bacterium

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ctsg

cathepsin G

acts_upstream_of_or_within

ISO

MGI:2182170 (PMID:11907569)

NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353

Ncf1

neutrophil cytosolic factor 1

acts_upstream_of_or_within

ISO
IEA

MGI:3576788 (PMID:11907569)
GO_REF:0000107

GO_REF:0000107

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

NLR family, pyrin domain containing 6

acts_upstream_of_or_within

ISO
IEA

(PMID:30248149)
GO_REF:0000107

PMID:30248149

GO_REF:0000107

NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113

NLRP1 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NLR family, pyrin domain containing 1A

involved_in

ISO

(PMID:22665479), (PMID:27662089), (PMID:31484767), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856)

PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More...

NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180

NLRP3 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atat1

alpha tubulin acetyltransferase 1

acts_upstream_of

ISO
IEA

(PMID:23502856)
GO_REF:0000107

GO_REF:0000107

NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,844,616...2,861,964

Gkn2

gastrokine 2

acts_upstream_of_or_within

ISO
IEA

(PMID:32226647)
GO_REF:0000107

PMID:32226647

GO_REF:0000107

NCBI chr 4:119,778,326...119,824,366
Ensembl chr 4:119,818,280...119,824,363

Kcnj8

potassium inwardly-rectifying channel, subfamily J, member 8

acts_upstream_of_or_within

ISO
IEA

MGI:2180015 (PMID:28928055)
GO_REF:0000107

PMID:28928055

GO_REF:0000107

NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:175,508,912...175,515,603

Nlrp3

NLR family, pyrin domain containing 3

involved_in
acts_upstream_of_or_within

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:23582325), (PMID:26173909), (PMID:27043286), (PMID:28465465), (PMID:28656979), (PMID:28716882), (PMID:28943315), (PMID:30487600), (PMID:34615873), (PMID:34861190)
MGI:5465108 (PMID:22753929)

PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More...

GO_REF:0000024 GO_REF:0000107

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

Pycard

PYD and CARD domain containing

involved_in

ISO
IEA

(PMID:27432880)
GO_REF:0000107

PMID:27432880

GO_REF:0000107

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

Sirt2

sirtuin 2

acts_upstream_of

ISO
IEA

(PMID:23502856)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:84,052,903...84,076,975

NLRP6 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NLR family, pyrin domain containing 6

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:32424362), (PMID:34678144)
GO_REF:0000107
(PMID:30674671), (PMID:31932628), (PMID:34678144)

PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Rnf34

ring finger protein 34

involved_in

ISO
IEA
ISS

(PMID:25012219)
GO_REF:0000107
GO_REF:0000024

PMID:25012219

GO_REF:0000024 GO_REF:0000107

NCBI chr12:39,364,461...39,385,391
Ensembl chr12:33,703,673...33,724,586

nucleotide-binding oligomerization domain containing 1 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nfkbia

NFKB inhibitor alpha

acts_upstream_of_or_within

ISO

(PMID:18261938)

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

Nod1

nucleotide-binding oligomerization domain containing 1

involved_in

ISO
IEA

(PMID:11058605), (PMID:12791997), (PMID:12796777)
GO_REF:0000107
(PMID:27007849)

PMID:11058605 PMID:12791997 PMID:12796777 PMID:27007849

GO_REF:0000107

NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404

receptor-interacting serine-threonine kinase 2

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:29452636), (PMID:30279485)
GO_REF:0000107
MGI:2660793 (PMID:11894098)

PMID:11894098 PMID:29452636 PMID:30279485

GO_REF:0000107

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

toll-like receptor 4

acts_upstream_of

ISO
IEA

(PMID:18261938)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Xiap

X-linked inhibitor of apoptosis

involved_in

ISO
IEA

(PMID:29452636)
GO_REF:0000107

PMID:29452636

GO_REF:0000107

NCBI chr X:125,756,107...125,803,979
Ensembl chr X:120,897,907...120,934,700

nucleotide-binding oligomerization domain containing 2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Inava

innate immunity activator

involved_in

ISO
IEA

(PMID:28436939)
GO_REF:0000107

PMID:28436939

GO_REF:0000107

NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729

Irf5

interferon regulatory factor 5

involved_in

ISO
IEA

(PMID:22412986)
GO_REF:0000107

PMID:22412986

GO_REF:0000107

NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267

immunity-related GTPase M

involved_in

ISO

(PMID:25891078)

PMID:25891078

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

Lacc1

laccase domain containing 1

involved_in

ISO

(PMID:31875558)

PMID:31875558

NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545

Nfkbia

NFKB inhibitor alpha

acts_upstream_of_or_within

ISO

(PMID:18261938)

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:12527755)
GO_REF:0000107
(PMID:15692052), (PMID:27007849)
(PMID:23892723)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)

PMID:12527755 PMID:12626759 PMID:15044951 PMID:15692052 PMID:17355968 More...

GO_REF:0000107

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Otulin

OTU deubiquitinase with linear linkage specificity

involved_in

ISO
IEA

(PMID:23806334)
GO_REF:0000107

PMID:23806334

GO_REF:0000107

NCBI chr 2:78,290,437...78,316,633
Ensembl chr 2:78,290,959...78,316,422

RELA proto-oncogene, NF-kB subunit

acts_upstream_of_or_within

ISO
IEA

(PMID:12527755)
GO_REF:0000107

PMID:12527755

GO_REF:0000107

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

receptor-interacting serine-threonine kinase 2

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)
GO_REF:0000107
(PMID:17947236)
MGI:2660793 (PMID:11894098)

PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:17947236 More...

GO_REF:0000107

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

toll-like receptor 4

acts_upstream_of

ISO
IEA

(PMID:18261938)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Xiap

X-linked inhibitor of apoptosis

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:19667203), (PMID:22607974), (PMID:29452636)
GO_REF:0000024

PMID:19667203 PMID:22607974 PMID:29452636

GO_REF:0000024 GO_REF:0000107

NCBI chr X:125,756,107...125,803,979
Ensembl chr X:120,897,907...120,934,700

pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cyclic GMP-AMP synthase

involved_in

ISO
IEA

(PMID:23258413)
GO_REF:0000107

PMID:23258413

GO_REF:0000107

NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496

Clec4e

C-type lectin domain family 4, member E

involved_in

ISO
ISS

(PMID:24101491)
GO_REF:0000024

PMID:24101491

GO_REF:0000024

NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767

Inava

innate immunity activator

involved_in

ISO
IEA

(PMID:28436939)
GO_REF:0000107

PMID:28436939

GO_REF:0000107

NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729

Lacc1

laccase domain containing 1

involved_in

ISO

(PMID:28593945), (PMID:31875558)

PMID:28593945 PMID:31875558

NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545

Nod1

nucleotide-binding oligomerization domain containing 1

involved_in

ISO
IEA

(PMID:31649195)
GO_REF:0000107

PMID:31649195

GO_REF:0000107

NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404

nucleotide-binding oligomerization domain containing 2

involved_in

ISO
IEA

(PMID:31649195)
GO_REF:0000107

PMID:31649195

GO_REF:0000107

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Rnf144a

ring finger protein 144A

involved_in

ISO
IEA

(PMID:37955227)
GO_REF:0000107

PMID:37955227

GO_REF:0000107

NCBI chr 6:48,628,241...48,748,241
Ensembl chr 6:42,903,174...43,020,012

stimulator of interferon response cGAMP interactor 1

involved_in

ISO
IEA

(PMID:23910378)
GO_REF:0000107

PMID:23910378

GO_REF:0000107

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

toll-like receptor 7

involved_in

IEA

GO_REF:0000117

GO_REF:0000117

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

toll-like receptor 8

involved_in

IEA

GO_REF:0000117

GO_REF:0000117

NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549

toll-like receptor 9

involved_in

IEA

GO_REF:0000117

GO_REF:0000117

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

positive regulation of AIM2 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

guanylate binding protein 2

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:25774715), (PMID:25774716)
GO_REF:0000107

PMID:25774715 PMID:25774716

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571

guanylate binding protein 5

involved_in

ISO
IEA

(PMID:25774715), (PMID:25774716)
GO_REF:0000107

PMID:25774715 PMID:25774716

GO_REF:0000107

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

positive regulation of antibacterial peptide biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

ISO

(PMID:18167348)

PMID:18167348

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

positive regulation of antibacterial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Klk1c10

kallikrein 1-related peptidase C10

involved_in

ISO

(PMID:18714013)

PMID:18714013

NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:94,402,993...94,407,052

Klk5

kallikrein related-peptidase 5

involved_in

ISO
IEA

(PMID:17012259)
GO_REF:0000107

PMID:17012259

GO_REF:0000107

NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666

Klk7

kallikrein-related peptidase 7

involved_in

IEA
ISO

GO_REF:0000107
(PMID:17012259)

PMID:17012259

GO_REF:0000107

NCBI chr 1:94,267,170...94,271,361
Ensembl chr 1:94,266,605...94,271,332

Pgc

progastricsin

involved_in

ISO
IEA

(PMID:12759353)
GO_REF:0000107

PMID:12759353

GO_REF:0000107

NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682

positive regulation of antifungal innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pla2g5

phospholipase A2, group V

involved_in

ISS
ISO

GO_REF:0000024
(PMID:19342668)

PMID:19342668

GO_REF:0000024

NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658

Spi1

Spi-1 proto-oncogene

involved_in

ISO
IEA

(PMID:30911105)
GO_REF:0000107

PMID:30911105

GO_REF:0000107

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

Trim62

tripartite motif-containing 62

involved_in

ISO

(PMID:26488816)

PMID:26488816

NCBI chr 5:146,516,349...146,545,015
Ensembl chr 5:141,231,523...141,259,915

positive regulation of antimicrobial humoral response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aconitate decarboxylase 1

involved_in

ISO
IEA

(PMID:23610393)
GO_REF:0000107

PMID:23610393

GO_REF:0000107

NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529

cathelicidin antimicrobial peptide

IMP

RGD

PMID:18227173

RGD:438738460

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

positive regulation of antimicrobial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il17a

interleukin 17A

involved_in

IEA
ISO

GO_REF:0000107
(PMID:19144317)

PMID:19144317

GO_REF:0000107

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

Il17f

interleukin 17F

involved_in

IEA
ISO

GO_REF:0000107
(PMID:19144317)

PMID:19144317

GO_REF:0000107

NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482

positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

ISO

MGI:3529594 (PMID:15692051)

PMID:15692051

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

positive regulation of cGAS/STING signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btk

Bruton tyrosine kinase

involved_in

ISO
IEA

(PMID:25704810)
GO_REF:0000107

PMID:25704810

GO_REF:0000107

NCBI chr X:102,016,070...102,055,448
Ensembl chr X:97,722,802...97,761,853

Map3k7

mitogen activated protein kinase kinase kinase 7

involved_in

ISO

(PMID:37832545)

PMID:37832545

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

Marchf5

membrane associated ring-CH-type finger 5

involved_in

IEA
ISO

GO_REF:0000107
(PMID:37916870)

PMID:37916870

GO_REF:0000107

NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632

Rnf39

ring finger protein 39

involved_in

ISO

(PMID:39255680)

PMID:39255680

NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,604,794...1,610,283

Slc19a1

solute carrier family 19 member 1

involved_in

ISO
IEA

(PMID:36745868)
GO_REF:0000107

PMID:36745868

GO_REF:0000107

NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,584,411...11,601,972

Tab1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

involved_in

ISO
IEA

(PMID:37832545)
GO_REF:0000107

PMID:37832545

GO_REF:0000107

NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058

Zdhhc9

zinc finger DHHC-type palmitoyltransferase 9

involved_in

ISO
IEA

(PMID:37802025)
GO_REF:0000107

PMID:37802025

GO_REF:0000107

NCBI chr X:132,230,243...132,266,139
Ensembl chr X:127,352,345...127,388,245

positive regulation of innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adam8

ADAM metallopeptidase domain 8

involved_in

ISO
IEA

(PMID:20683884)
GO_REF:0000107

PMID:20683884

GO_REF:0000107

NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801

Akirin2

akirin 2

involved_in

ISS
ISO
IBA

GO_REF:0000024
(PMID:25107474)
GO_REF:0000033

PMID:25107474

GO_REF:0000024 GO_REF:0000033

NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568

Card9

caspase recruitment domain family, member 9

acts_upstream_of_or_within

ISO
IEA

MGI:3698412 (PMID:17187069)
GO_REF:0000107

PMID:17187069

GO_REF:0000107

NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237

Cpt1a

carnitine palmitoyltransferase 1A

involved_in

ISO
IEA

(PMID:38016475)
GO_REF:0000107

PMID:38016475

GO_REF:0000107

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

Dhx9

DExH-box helicase 9

involved_in

ISO

(PMID:28636595)

PMID:28636595

NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069

Ereg

epiregulin

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:16182244)

PMID:16182244

GO_REF:0000024 GO_REF:0000107

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

Fadd

Fas associated via death domain

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

Fpr2

formyl peptide receptor 2

involved_in

ISO
IEA

(PMID:25505240)
GO_REF:0000107

PMID:25505240

GO_REF:0000107

NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019

guanylate binding protein 5

involved_in

ISO
IEA

(PMID:22461501)
GO_REF:0000107

PMID:22461501

GO_REF:0000107

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

hepatitis A virus cellular receptor 2

involved_in

ISO

UniProtKB:O08573 (PMID:20937702)

PMID:20937702

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

high mobility group box 1

involved_in

ISO

(PMID:19890330)

PMID:19890330

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

Hmgb2

high mobility group box 2

involved_in

ISO

(PMID:19890330)

PMID:19890330

NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140

Ifi35

interferon-induced protein 35

involved_in

ISO
IEA

(PMID:29038465)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952

Kat5

lysine acetyltransferase 5

involved_in

ISO

(PMID:32817552)

PMID:32817552

NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:202,895,751...202,903,458

galectin 9

involved_in

ISO

UniProtKB:Q8VIM0 (PMID:20937702)

PMID:20937702

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

N-myc (and STAT) interactor

involved_in

ISO

(PMID:29038465)

NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within
involved_in

ISO

MGI:3529594 (PMID:15692051)
(PMID:21156799)

PMID:15692051 PMID:21156799

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Plscr1

phospholipid scramblase 1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:15308695)

PMID:15308695

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692

Polr3b

RNA polymerase III subunit B

involved_in

ISO

(PMID:19609254)

PMID:19609254

NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598

Polr3c

RNA polymerase III subunit C

involved_in

ISO
IEA
ISS

(PMID:19609254)
GO_REF:0000107
GO_REF:0000024

PMID:19609254

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:184,246,201...184,262,150
Ensembl chr 2:184,246,204...184,262,208

Polr3d

RNA polymerase III subunit D

involved_in

ISO
IEA

(PMID:19631370)
GO_REF:0000107

PMID:19631370

GO_REF:0000107

NCBI chr15:45,511,587...45,516,256
Ensembl chr15:45,511,589...45,516,353

Polr3f

RNA polymerase III subunit F

involved_in

ISO
IEA

(PMID:19631370)
GO_REF:0000107

PMID:19631370

GO_REF:0000107

NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837

Polr3g

RNA polymerase III subunit G

involved_in

ISO

(PMID:19609254), (PMID:19631370)

PMID:19609254 PMID:19631370

NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125

Riok3

RIO kinase 3

involved_in

ISO
IEA

(PMID:24807708)
GO_REF:0000107

PMID:24807708

GO_REF:0000107

NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343

Rnf185

ring finger protein 185

involved_in

ISO
IEA

(PMID:28273161)
GO_REF:0000107

PMID:28273161

GO_REF:0000107

NCBI chr14:82,516,153...82,554,199
Ensembl chr14:78,292,516...78,329,864

solute carrier family 15 member 4

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:32433612)

GO_REF:0000024 GO_REF:0000107

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

Srebf1

sterol regulatory element binding transcription factor 1

involved_in

ISO

(PMID:21531336)

PMID:21531336

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

TLR adaptor interacting with endolysosomal SLC15A4

involved_in

ISO
IEA

(PMID:32433612)
GO_REF:0000107

GO_REF:0000107

NCBI chr X:50,403,962...50,423,141
Ensembl chr X:50,361,248...50,423,269

TIR domain containing adaptor protein

involved_in

ISO

(PMID:16301656)

PMID:16301656

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

toll-like receptor 8

involved_in

ISO

(PMID:16123302)

PMID:16123302

NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549

tripartite motif containing 56

involved_in

ISO

(PMID:29426904)

PMID:29426904

NCBI chr12:25,193,224...25,204,032
Ensembl chr12:19,551,521...19,567,462

Zdhhc4

zinc finger DHHC-type palmitoyltransferase 4

involved_in

ISO
IEA

(PMID:35606353)
GO_REF:0000107

PMID:35606353

GO_REF:0000107

NCBI chr12:16,344,447...16,358,493
Ensembl chr12:11,230,902...11,244,898

positive regulation of MDA-5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ankrd17

ankyrin repeat domain 17

involved_in

ISO
IEA

(PMID:22328336)
GO_REF:0000107

PMID:22328336

GO_REF:0000107

NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617

Ddx60

DEXD/H-box helicase 60

involved_in

ISO

(PMID:21791617)

PMID:21791617

NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526

DEXH-box helicase 58

involved_in

ISO
IEA

(PMID:20080593)
GO_REF:0000107

PMID:20080593

GO_REF:0000107

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Usp17la2

ubiquitin specific peptidase 17-like a2

involved_in

ISO

(PMID:20368735)

PMID:20368735

NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192

positive regulation of MyD88-dependent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ccdc134

coiled-coil domain containing 134

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:38670073)

PMID:38670073

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:113,644,557...113,659,050
Ensembl chr 7:113,644,639...113,659,050

positive regulation of natural killer cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD160 molecule

involved_in

ISO
IEA

(PMID:17307798)
GO_REF:0000107

PMID:17307798

GO_REF:0000107

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

CD226 molecule

acts_upstream_of_or_within
involved_in

ISO
IEA

MGI:4454325 (PMID:24658051)
GO_REF:0000107
GO_REF:0000002

RGD
Ensembl
InterPro

PMID:24658051

GO_REF:0000002 GO_REF:0000107

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

Clnk

cytokine-dependent hematopoietic cell linker

involved_in

ISO

(PMID:16439675)

PMID:16439675

NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208

Gimap5

GTPase, IMAP family member 5

IMP

RGD

PMID:15100275

RGD:2303778

NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086

Il21

interleukin 21

acts_upstream_of_or_within

ISO

(PMID:14764669)

PMID:14764669

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

RT1 class Ia, locus A2

involved_in

ISO

(PMID:30134159)

PMID:30134159

NCBI chr20:4,870,939...4,910,183

RT1 class I, locus CE5

involved_in

ISO

(PMID:27455421)

PMID:27455421

NCBI chr20:3,403,418...3,479,476

RT1 class Ib, locus M3, gene 1

involved_in

ISO

(PMID:16366734), (PMID:19304799), (PMID:23184984)

PMID:16366734 PMID:19304799 PMID:23184984

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

positive regulation of natural killer cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ap1g1

adaptor related protein complex 1 subunit gamma 1

involved_in

ISO
IEA

(PMID:23632890)
GO_REF:0000107

GO_REF:0000107

NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167

CD160 molecule

involved_in

ISO

(PMID:19109136)

PMID:19109136

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

killer cell lectin like receptor C2

involved_in

ISO

(PMID:21825173)

PMID:21825173

NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843

Lamp1

lysosomal-associated membrane protein 1

involved_in

ISO
IEA

(PMID:23632890)
GO_REF:0000107

GO_REF:0000107

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

RT1 class I, locus CE5

involved_in

ISO

(PMID:27455421)

PMID:27455421

NCBI chr20:3,403,418...3,479,476

positive regulation of natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ap1g1

adaptor related protein complex 1 subunit gamma 1

involved_in

ISO
IEA

(PMID:23632890)
GO_REF:0000107

GO_REF:0000107

NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167

Bid

BH3 interacting domain death agonist

IMP

RGD

PMID:17893612

RGD:408346749

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

Cadm1

cell adhesion molecule 1

involved_in

ISO
IEA
ISS

(PMID:15811952)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
HGNC

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:47,847,325...48,182,833

CD160 molecule

involved_in

ISO
IEA

(PMID:12486241), (PMID:17307798)
GO_REF:0000107

PMID:12486241 PMID:17307798

GO_REF:0000107

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

CD226 molecule

involved_in

ISO
IEA

(PMID:16304049)
GO_REF:0000107

GO_REF:0000107

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

Crtam

cytotoxic and regulatory T cell molecule

involved_in

ISO
IEA

(PMID:15811952)
GO_REF:0000107

GO_REF:0000107

NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343

Gimap5

GTPase, IMAP family member 5

IMP

RGD

PMID:15100275

RGD:2303778

NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086

Il12a

interleukin 12A

involved_in

ISO
IEA

(PMID:2204066)
GO_REF:0000107

PMID:2204066

GO_REF:0000107

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

Il18rap

interleukin 18 receptor accessory protein

acts_upstream_of_or_within

ISO
IEA

MGI:3579137 (PMID:15843532)
GO_REF:0000107

PMID:15843532

GO_REF:0000107

NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959

Il21

interleukin 21

involved_in
acts_upstream_of_or_within

ISO
IBA
IEA

(PMID:18005035)
GO_REF:0000033
(PMID:14764669)
GO_REF:0000107

PMID:14764669 PMID:18005035

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

Klrb1b

killer cell lectin like receptor B1B

acts_upstream_of_or_within

ISO

(PMID:10229823), (PMID:10229828)

MGI
RGD

PMID:10229823 PMID:10229828

NCBI chr 4:161,948,259...161,961,537
Ensembl chr 4:161,890,577...161,961,675

Klrc1

killer cell lectin like receptor C1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425

killer cell lectin like receptor C2

involved_in

ISO

(PMID:9754572)

PMID:9754572

NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843

killer cell lectin like receptor D1

involved_in

ISO
IBA
IEA

(PMID:9754572)
GO_REF:0000033
GO_REF:0000107

PMID:9754572

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518

killer cell lectin like receptor E1

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:15294961)
GO_REF:0000107
GO_REF:0000033

PMID:15294961

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638

Klrh1

killer cell lectin-like receptor subfamily H, member 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,288,228...163,301,977
Ensembl chr 4:163,288,229...163,300,535

Klri1

killer cell lectin-like receptor family I member 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870

Klri2

killer cell lectin-like receptor family I member 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484

UniProt
RGD
GO_Central
InterPro

killer cell lectin like receptor K1

involved_in
acts_upstream_of_or_within

ISS
ISO
IBA
IEA

GO_REF:0000024
(PMID:15294961)
(PMID:12645935)
GO_REF:0000033
GO_REF:0000002

PMID:12645935 PMID:15294961

GO_REF:0000002 GO_REF:0000024 GO_REF:0000033

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

Lag3

lymphocyte activating 3

acts_upstream_of_or_within

ISO
IEA

MGI:2176269 (PMID:8602528)
GO_REF:0000107

PMID:8602528

GO_REF:0000107

NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404

Lamp1

lysosomal-associated membrane protein 1

involved_in

ISO
IEA

(PMID:23632890)
GO_REF:0000107

RGD
GO_Central
Ensembl
InterPro

GO_REF:0000107

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

Ly49s3

Ly-49 stimulatory receptor 3

IDA

RGD

PMID:12077224

RGD:633264

Ensembl chr 4:164,122,072...164,341,692

Ncr3

natural cytotoxicity triggering receptor 3

involved_in

ISO
IBA
IEA

(PMID:16304049)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799

nectin cell adhesion molecule 2

involved_in

ISO
IEA

(PMID:16304049)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

ISO

(PMID:16304049)

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

Raet1e

retinoic acid early transcript 1E

involved_in

ISO

(PMID:18544572)

PMID:18544572

NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755

Raet1l

retinoic acid early transcript 1L

IDA

RGD

PMID:20306467

RGD:9685184

NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410

Raet1ll1

retinoic acid early transcript 1L like 1

IDA

RGD

PMID:20306467

RGD:9685184

NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656

Rasgrp1

RAS guanyl releasing protein 1

involved_in

ISO
IEA

(PMID:19933860)
GO_REF:0000107

PMID:19933860

GO_REF:0000107

NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056

RT1 class Ia, locus A2

involved_in

ISO

(PMID:23335510)

PMID:23335510

NCBI chr20:4,870,939...4,910,183

RT1 class Ib, locus M3, gene 1

acts_upstream_of_or_within

ISO

MGI:3701255 (PMID:16476767)

PMID:16476767

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

Sh2d1a

SH2 domain containing 1A

acts_upstream_of_or_within

ISO
IEA

MGI:1349420|MGI:3575311|MGI:3622649 (PMID:16127454), (PMID:19648922)
GO_REF:0000107

PMID:16127454 PMID:19648922

GO_REF:0000107

NCBI chr X:121,373,693...121,401,923

Sh2d1b2

SH2 domain containing 1B2

acts_upstream_of_or_within

ISO
IEA

MGI:1328352|MGI:1349420|MGI:98923 (PMID:19648922), (PMID:20962259)
GO_REF:0000107

PMID:19648922 PMID:20962259

GO_REF:0000107

NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509

Slamf6

SLAM family member 6

involved_in

ISO

(PMID:16920955)

PMID:16920955

NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300

Stat5a

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

ISO
IEA

MGI:1857249 (PMID:9841920)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Stat5b

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

ISO
IEA

MGI:2181592 (PMID:9841920)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Vav1

vav guanine nucleotide exchange factor 1

acts_upstream_of_or_within

ISO
IEA

MGI:1349420|MGI:3622649 (PMID:20962259)
GO_REF:0000107

PMID:20962259

GO_REF:0000107

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD226 molecule

involved_in

ISO
IEA

(PMID:12913096)
GO_REF:0000107

GO_REF:0000107

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

Crtam

cytotoxic and regulatory T cell molecule

involved_in

ISO
IEA
IBA

(PMID:15811952)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343

Il12a

interleukin 12A

involved_in

ISO
IEA

(PMID:7903063)
GO_REF:0000107

PMID:7903063

GO_REF:0000107

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

Il12b

interleukin 12B

involved_in

ISO
IEA

(PMID:7903063)
GO_REF:0000107

PMID:7903063

GO_REF:0000107

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

killer cell lectin like receptor K1

IMP

RGD

PMID:16323246

RGD:9685180

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

nectin cell adhesion molecule 2

involved_in

ISO
IEA
IBA

(PMID:12913096)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

ISO

(PMID:12913096)

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

Raet1ll1

retinoic acid early transcript 1L like 1

IMP

RGD

PMID:16323246

RGD:9685180

NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656

positive regulation of natural killer cell mediated immune response to tumor cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD160 molecule

involved_in

ISO
IEA

(PMID:25711213)
GO_REF:0000107

PMID:25711213

GO_REF:0000107

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

positive regulation of natural killer cell mediated immunity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dpp4

dipeptidylpeptidase 4

IMP

RGD

PMID:19327106

RGD:41408336

NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901

Rasgrp4

RAS guanyl releasing protein 4

involved_in

ISS
ISO

GO_REF:0000024
(PMID:26982501)

PMID:26982501

GO_REF:0000024

NCBI chr 1:84,433,033...84,452,841
Ensembl chr 1:84,433,064...84,451,896

RT1 class Ia, locus A2

involved_in

ISO

(PMID:9754572)

PMID:9754572

NCBI chr20:4,870,939...4,910,183

positive regulation of neutrophil mediated killing of fungus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arg1

arginase 1

involved_in

ISO
IEA

(PMID:15546957)
GO_REF:0000107

PMID:15546957

GO_REF:0000107

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

Cxcl1

C-X-C motif chemokine ligand 1

involved_in

ISO

(PMID:10725737)

PMID:10725737

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

Pomc

proopiomelanocortin

involved_in

ISO

(PMID:10670585)

PMID:10670585

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

positive regulation of neutrophil mediated killing of gram-negative bacterium

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2R like trypsin receptor 1

involved_in

ISO
IEA

(PMID:21501162)
GO_REF:0000107

PMID:21501162

GO_REF:0000107

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

positive regulation of NLRP3 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atat1

alpha tubulin acetyltransferase 1

acts_upstream_of_or_within

ISO
IEA

(PMID:23502856)
GO_REF:0000107

GO_REF:0000107

NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,844,616...2,861,964

Brcc3

BRCA1/BRCA2-containing complex subunit 3

involved_in

ISS
ISO

GO_REF:0000024
(PMID:23246432)
(PMID:28943315)

PMID:23246432 PMID:28943315

GO_REF:0000024

NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080

Btk

Bruton tyrosine kinase

involved_in

ISO
IEA

(PMID:34554188)
GO_REF:0000107

PMID:34554188

GO_REF:0000107

NCBI chr X:102,016,070...102,055,448
Ensembl chr X:97,722,802...97,761,853

Casp4

caspase 4

involved_in

ISO

(PMID:26173909)

PMID:26173909

NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092

Cd36

CD36 molecule

involved_in

ISS
ISO

GO_REF:0000024
(PMID:23812099)

PMID:23812099

GO_REF:0000024

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

Cd36l1

CD36 molecule like 1

involved_in

ISS

GO_REF:0000024

GO_REF:0000024

NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903

DEAD-box helicase 3, X-linked

involved_in

ISO
IEA

(PMID:31511697)
GO_REF:0000107

PMID:31511697

GO_REF:0000107

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

Dhx33

DEAH-box helicase 33

involved_in

ISO
IEA

(PMID:23871209)
GO_REF:0000107

PMID:23871209

GO_REF:0000107

NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567

guanylate binding protein 5

involved_in

ISO
IEA

(PMID:22461501)
GO_REF:0000107

PMID:22461501

GO_REF:0000107

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

Kcnk6

potassium two pore domain channel subfamily K member 6

involved_in

ISS

GO_REF:0000024

GO_REF:0000024

NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677

Lats1

large tumor suppressor kinase 1

involved_in

ISO
IEA

(PMID:39173637)
GO_REF:0000107

PMID:39173637

GO_REF:0000107

NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640

Lats2

large tumor suppressor kinase 2

involved_in

ISO
IEA

(PMID:39173637)
GO_REF:0000107

PMID:39173637

GO_REF:0000107

NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220

LOC134486712

platelet glycoprotein 4-like

involved_in

ISS

GO_REF:0000024

GO_REF:0000024

Mapk8

mitogen-activated protein kinase 8

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:28943315)
GO_REF:0000107

PMID:28943315

GO_REF:0000024 GO_REF:0000107

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981

Marchf5

membrane associated ring-CH-type finger 5

involved_in

IEA
ISO

GO_REF:0000107
(PMID:37575012)

PMID:37575012

GO_REF:0000107

NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632

Mark4

microtubule affinity regulating kinase 4

involved_in

ISO
IEA

(PMID:28656979)
GO_REF:0000107

PMID:28656979

GO_REF:0000107

NCBI chr 1:79,075,353...79,108,882
Ensembl chr 1:79,068,904...79,108,556

mitochondrial antiviral signaling protein

involved_in

ISO

(PMID:23582325)

PMID:23582325

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

Mir21

microRNA 21

IDA

RGD

PMID:29084974

RGD:41404715

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

MYD88, innate immune signal transduction adaptor

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:33718825)

UniProt
GO_Central
RGD
Ensembl

PMID:33718825

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

Nek7

NIMA-related kinase 7

involved_in

ISS
IBA
ISO
IEA

GO_REF:0000024
GO_REF:0000033
(PMID:31189953), (PMID:36442502), (PMID:39173637)
(PMID:26642356), (PMID:26814970)
GO_REF:0000107

PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 PMID:39173637

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296

P2rx7

purinergic receptor P2X 7

involved_in

ISS
ISO

GO_REF:0000024
(PMID:29958799)

PMID:29958799

GO_REF:0000024

NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619

phospholipase C, gamma 2

acts_upstream_of_or_within

ISO

(PMID:32514138)

PMID:32514138

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Ppp2ca

protein phosphatase 2 catalytic subunit alpha

involved_in

ISS
ISO

GO_REF:0000024
(PMID:28465465)

PMID:28465465

GO_REF:0000024

NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862

Prkd1

protein kinase D1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:28716882)

PMID:28716882

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042

protein tyrosine phosphatase, non-receptor type 22

involved_in

ISO

(PMID:27043286)

PMID:27043286

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

Stmp1

short transmembrane mitochondrial protein 1

involved_in

ISO

(PMID:31836654)

PMID:31836654

NCBI chr 4:63,927,523...63,937,355

toll-like receptor 4

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:23812099)

PMID:23812099

GO_REF:0000024 GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

toll-like receptor 6

involved_in

ISO
IEA

(PMID:23812099)
GO_REF:0000107

PMID:23812099

GO_REF:0000107

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

Usp50

ubiquitin specific peptidase 50

acts_upstream_of_or_within

ISO
IEA

(PMID:28094437)
GO_REF:0000107

PMID:28094437

GO_REF:0000107

NCBI chr 3:114,012,104...114,035,468
Ensembl chr 3:114,011,702...114,035,476

Zdhhc1

zinc finger, DHHC-type containing 1

involved_in

ISO

(PMID:39173637)

PMID:39173637

NCBI chr19:50,260,445...50,285,634
Ensembl chr19:33,350,533...33,375,616

Zdhhc5

zinc finger DHHC-type palmitoyltransferase 5

involved_in

ISO
IEA

(PMID:38092000)
GO_REF:0000107

PMID:38092000

GO_REF:0000107

NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

solute carrier family 15 member 4

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:19570976), (PMID:21277849)
GO_REF:0000024

PMID:19570976 PMID:21277849

GO_REF:0000024 GO_REF:0000107

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

Slc46a2

solute carrier family 46, member 2

involved_in

ISO
IEA

(PMID:28539433)
GO_REF:0000107

PMID:28539433

GO_REF:0000107

NCBI chr 5:74,800,226...74,808,128
Ensembl chr 5:74,800,226...74,808,128

toll-like receptor 4

acts_upstream_of_or_within

ISO
IEA

(PMID:18261938)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hspa1a

heat shock protein family A (Hsp70) member 1A

involved_in

ISO

UniProtKB:Q9HC29 (PMID:24790089)

PMID:24790089

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

Hspa1b

heat shock protein family A (Hsp70) member 1B

involved_in

ISO

UniProtKB:Q9HC29 (PMID:24790089)

PMID:24790089

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

Nagk

N-acetylglucosamine kinase

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:36002575)

PMID:36002575

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137

Peli3

pellino E3 ubiquitin protein ligase family member 3

acts_upstream_of_or_within

ISO

(PMID:23892723)

PMID:23892723

NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:202,232,228...202,242,857

Slc15a3

solute carrier family 15 member 3

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:24695226)

PMID:24695226

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157

solute carrier family 15 member 4

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:24695226)
GO_REF:0000024

PMID:24695226

GO_REF:0000024 GO_REF:0000107

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

toll-like receptor 4

acts_upstream_of_or_within

ISO
IEA

(PMID:18261938)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

positive regulation of pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Zdhhc5

zinc finger DHHC-type palmitoyltransferase 5

involved_in

ISO
IEA
IBA

(PMID:31649195)
GO_REF:0000107
GO_REF:0000033

PMID:31649195

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921

positive regulation of respiratory burst involved in inflammatory response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

lipopolysaccharide binding protein

involved_in

IEA
ISO

GO_REF:0000107
(PMID:9338787)

PMID:9338787

GO_REF:0000107

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

Rps19

ribosomal protein S19

involved_in

ISO

(PMID:15750715)

PMID:15750715

NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508

positive regulation of response to type II interferon

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hpx

hemopexin

acts_upstream_of_or_within

ISO
IEA

MGI:2447193 (PMID:18641331)
GO_REF:0000107

PMID:18641331

GO_REF:0000107

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

positive regulation of RIG-I signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ankrd17

ankyrin repeat domain 17

involved_in

ISO
IEA

(PMID:22328336)
GO_REF:0000107

PMID:22328336

GO_REF:0000107

NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617

Ddx60

DEXD/H-box helicase 60

involved_in

ISO

(PMID:21791617)

PMID:21791617

NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526

DEXH-box helicase 58

involved_in

ISO
IEA

(PMID:20080593)
GO_REF:0000107

PMID:20080593

GO_REF:0000107

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Hdac6

histone deacetylase 6

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr X:17,222,538...17,244,373
Ensembl chr X:14,551,044...14,572,441

2'-5'-oligoadenylate synthetase-like

involved_in

ISO

(PMID:25925578)

PMID:25925578

NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641

Pum1

pumilio RNA-binding family member 1

involved_in

ISO
IEA

(PMID:25340845)
GO_REF:0000107

PMID:25340845

GO_REF:0000107

NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039

Pum2

pumilio RNA-binding family member 2

involved_in

ISO
IEA

(PMID:25340845)
GO_REF:0000107

PMID:25340845

GO_REF:0000107

NCBI chr 6:31,462,879...31,542,976
Ensembl chr 6:31,462,872...31,542,976

Trim15

tripartite motif containing 15

involved_in

ISO

(PMID:23077300)

PMID:23077300

NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249

Usp15

ubiquitin specific peptidase 15

involved_in

ISO
IEA

(PMID:24399297)
GO_REF:0000107

PMID:24399297

GO_REF:0000107

NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721

Usp17la2

ubiquitin specific peptidase 17-like a2

involved_in

ISO

(PMID:20368735)

PMID:20368735

NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192

Zc3hav1

zinc finger CCCH-type containing, antiviral 1

involved_in

ISO

(PMID:21102435)

PMID:21102435

NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428

Zcchc3

zinc finger CCHC-type containing 3

involved_in

ISO
IEA
IBA

(PMID:30193849)
GO_REF:0000107
GO_REF:0000033

PMID:30193849

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:140,872,460...140,875,292
Ensembl chr 3:140,872,460...140,882,408

positive regulation of toll-like receptor 13 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Treml4

triggering receptor expressed on myeloid cells-like 4

involved_in

ISO

(PMID:25848864)

PMID:25848864

NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253

positive regulation of toll-like receptor 2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cyba

cytochrome b-245 alpha chain

involved_in

ISO
IEA

(PMID:22423966)
GO_REF:0000107

PMID:22423966

GO_REF:0000107

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

F2R like trypsin receptor 1

involved_in

ISO
IEA

(PMID:19865078)
GO_REF:0000107

PMID:19865078

GO_REF:0000107

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

high mobility group box 1

involved_in

ISO

(PMID:16267105)

PMID:16267105

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

multifunctional ROCO family signaling regulator 1

involved_in

ISO
IEA

(PMID:26599367), (PMID:28471450)
GO_REF:0000107

PMID:26599367 PMID:28471450

GO_REF:0000107

NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743

Pja2

praja ring finger ubiquitin ligase 2

involved_in

ISO
IEA
ISS

(PMID:28471450)
GO_REF:0000107
GO_REF:0000024

PMID:28471450

GO_REF:0000024 GO_REF:0000107

NCBI chr 9:111,403,624...111,453,703
Ensembl chr 9:103,956,678...104,006,783

TIR domain containing adaptor protein

involved_in

ISO

(PMID:19509286)

PMID:19509286

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Tlr1

toll-like receptor 1

involved_in

ISO
IEA

ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949)
GO_REF:0000107

PMID:22198949

GO_REF:0000107

NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125

positive regulation of toll-like receptor 3 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cav1

caveolin 1

involved_in

ISO
IEA

(PMID:25204797)
GO_REF:0000107

GO_REF:0000107

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

F2R like trypsin receptor 1

involved_in

ISO
IEA

(PMID:19865078)
GO_REF:0000107

PMID:19865078

GO_REF:0000107

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

Flot1

flotillin 1

involved_in

ISO
IEA

(PMID:25204797)
GO_REF:0000107

GO_REF:0000107

NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978

Peli1

pellino E3 ubiquitin protein ligase 1

acts_upstream_of_or_within

ISO
IEA

MGI:4361448 (PMID:19734906)
GO_REF:0000107

PMID:19734906

GO_REF:0000107

NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285

protein tyrosine phosphatase, non-receptor type 22

involved_in

ISO

(PMID:23871208)

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

TIR domain containing adaptor protein

involved_in

ISO

(PMID:17322885)

PMID:17322885

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Trim3

tripartite motif-containing 3

involved_in

IEA
ISO

GO_REF:0000107
(PMID:32878999)

PMID:32878999

GO_REF:0000107

NCBI chr 1:169,362,751...169,385,430
Ensembl chr 1:159,944,908...159,973,600

Wdfy1

WD repeat and FYVE domain containing 1

involved_in

ISO
IEA
IBA

(PMID:25736436)
GO_REF:0000107
GO_REF:0000033

PMID:25736436

GO_REF:0000033 GO_REF:0000107

NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775

positive regulation of toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD14 molecule

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:24380872)

PMID:24380872

GO_REF:0000024 GO_REF:0000107

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261

F2R like trypsin receptor 1

involved_in

ISO
IEA

(PMID:18622013)
GO_REF:0000107

PMID:18622013

GO_REF:0000107

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

high mobility group box 1

involved_in

ISO

(PMID:16267105)

PMID:16267105

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

Ifi35

interferon-induced protein 35

involved_in

ISO
IEA

(PMID:29038465)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952

lipopolysaccharide binding protein

involved_in

ISO
IEA

(PMID:11528597)
GO_REF:0000107

PMID:11528597

GO_REF:0000107

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

lactotransferrin

involved_in

ISO

(PMID:20345905)

PMID:20345905

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

Ninj1

ninjurin 1

involved_in

ISS
ISO

GO_REF:0000024
(PMID:25860173)

PMID:25860173

GO_REF:0000024

NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704

Nr1h3

nuclear receptor subfamily 1, group H, member 3

involved_in

ISO
IEA

(PMID:18511497)
GO_REF:0000107

PMID:18511497

GO_REF:0000107

NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722

Peli1

pellino E3 ubiquitin protein ligase 1

acts_upstream_of_or_within

ISO
IEA

MGI:4361448 (PMID:19734906)
GO_REF:0000107

PMID:19734906

GO_REF:0000107

NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285

protein tyrosine phosphatase, non-receptor type 22

involved_in

ISO

(PMID:23871208)

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

TIR domain containing adaptor molecule 2

involved_in

ISO

(PMID:19412184)
(PMID:22685567)

PMID:19412184 PMID:22685567

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

TIR domain containing adaptor protein

involved_in

ISO

(PMID:19509286)

PMID:19509286

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Wdfy1

WD repeat and FYVE domain containing 1

involved_in

ISO
IEA
IBA

(PMID:25736436)
GO_REF:0000107
GO_REF:0000033

PMID:25736436

GO_REF:0000033 GO_REF:0000107

NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775

Znrf1

zinc and ring finger 1

involved_in

ISO
IEA

(PMID:28593998)
GO_REF:0000107

PMID:28593998

GO_REF:0000107

NCBI chr19:56,403,816...56,490,901
Ensembl chr19:39,496,527...39,580,969

positive regulation of toll-like receptor 7 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DEAD-box helicase 3, X-linked

involved_in

ISO

(PMID:30341167)

PMID:30341167

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

protein tyrosine phosphatase, non-receptor type 22

involved_in

ISO

(PMID:23871208)

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

Rsad2

radical S-adenosyl methionine domain containing 2

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:21435586)
GO_REF:0000107

PMID:21435586

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

solute carrier family 15 member 4

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:21045126), (PMID:25238095)
GO_REF:0000024
(PMID:25238095), (PMID:32433612)

PMID:21045126 PMID:25238095 PMID:32433612

GO_REF:0000024 GO_REF:0000107

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

TLR adaptor interacting with endolysosomal SLC15A4

involved_in

ISO
IEA

(PMID:32433612)
GO_REF:0000107

GO_REF:0000107

NCBI chr X:50,403,962...50,423,141
Ensembl chr X:50,361,248...50,423,269

Treml4

triggering receptor expressed on myeloid cells-like 4

involved_in

ISO
IBA

(PMID:25848864)
GO_REF:0000033

PMID:25848864

GO_REF:0000033

NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253

positive regulation of toll-like receptor 8 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DEAD-box helicase 3, X-linked

involved_in

ISO

(PMID:30341167)

PMID:30341167

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

solute carrier family 15 member 4

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:32433612)

GO_REF:0000024 GO_REF:0000107

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

TLR adaptor interacting with endolysosomal SLC15A4

involved_in

ISO
IEA

(PMID:32433612)
GO_REF:0000107

GO_REF:0000107

NCBI chr X:50,403,962...50,423,141
Ensembl chr X:50,361,248...50,423,269

positive regulation of toll-like receptor 9 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

high mobility group box 1

involved_in

ISS

GO_REF:0000024

GO_REF:0000024

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

protein tyrosine phosphatase, non-receptor type 22

involved_in

ISO

(PMID:23871208)

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

Rsad2

radical S-adenosyl methionine domain containing 2

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:21435586)
GO_REF:0000107

PMID:21435586

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

Rtn4

reticulon 4

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:25917084)
GO_REF:0000107

PMID:25917084

GO_REF:0000024 GO_REF:0000107

NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686

solute carrier family 15 member 4

involved_in

ISO
ISS
IEA

(PMID:25238095)
(PMID:21045126), (PMID:21277849), (PMID:25238095)
GO_REF:0000024
GO_REF:0000107

PMID:21045126 PMID:21277849 PMID:25238095

GO_REF:0000024 GO_REF:0000107

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

toll-like receptor 9

involved_in

ISO
IEA

(PMID:18931679)
GO_REF:0000107

PMID:18931679

GO_REF:0000107

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Treml4

triggering receptor expressed on myeloid cells-like 4

involved_in

ISO

(PMID:25848864)

PMID:25848864

NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253

Zdhhc3

zinc finger DHHC-type palmitoyltransferase 3

involved_in

ISO
IEA

(PMID:38169466)
GO_REF:0000107

PMID:38169466

GO_REF:0000107

NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:122,715,111...122,773,529

positive regulation of toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gdi1

GDP dissociation inhibitor 1

involved_in

ISO
IEA

(PMID:35343654)
GO_REF:0000107

PMID:35343654

GO_REF:0000107

NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272

Hsp90b1

heat shock protein 90 beta family member 1

involved_in

ISO
IEA

(PMID:11584270)
GO_REF:0000107

PMID:11584270

GO_REF:0000107

NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788

Lrch4

leucine rich repeats and calponin homology domain containing 4

involved_in

ISO

(PMID:16449650)

PMID:16449650

NCBI chr12:19,057,582...19,072,573
Ensembl chr12:19,057,587...19,068,577

phosphoinositide-3-kinase adaptor protein 1

involved_in

ISO

(PMID:20728433)

PMID:20728433

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

positive regulation of type I interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fadd

Fas associated via death domain

involved_in

ISO
IEA

(PMID:21109225)
GO_REF:0000107

PMID:21109225

GO_REF:0000107

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

Ikbke

inhibitor of nuclear factor kappa B kinase subunit epsilon

involved_in

ISO

(PMID:24882218)
(PMID:27129230)

PMID:24882218 PMID:27129230

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

interferon regulatory factor 3

acts_upstream_of_or_within

ISO

(PMID:17618271)

PMID:17618271

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

interferon regulatory factor 7

acts_upstream_of_or_within

ISO
IEA

(PMID:17618271)
GO_REF:0000107

PMID:17618271

GO_REF:0000107

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

Lsm14a

LSM14A mRNA processing body assembly factor

acts_upstream_of_or_within

ISO
IEA

(PMID:22745163)
GO_REF:0000107

PMID:22745163

GO_REF:0000107

NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276

mitochondrial antiviral signaling protein

involved_in

ISO

(PMID:16127453), (PMID:20451243)

PMID:16127453 PMID:20451243

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

Mmp12

matrix metallopeptidase 12

involved_in

IEA
ISO

GO_REF:0000107
(PMID:24784232)

PMID:24784232

GO_REF:0000107

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

NLR family, CARD domain containing 5

involved_in

ISO

(PMID:20061403)

PMID:20061403

NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121

Rbm47

RNA binding motif protein 47

involved_in

ISO
IEA

(PMID:34160127)
GO_REF:0000107

PMID:34160127

GO_REF:0000107

NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431

Rnf185

ring finger protein 185

involved_in

ISO
IEA
ISS

(PMID:28273161)
GO_REF:0000107
GO_REF:0000024

PMID:28273161

GO_REF:0000024 GO_REF:0000107

NCBI chr14:82,516,153...82,554,199
Ensembl chr14:78,292,516...78,329,864

stimulator of interferon response cGAMP interactor 1

involved_in

ISO
IEA

(PMID:23910378)
GO_REF:0000107

PMID:23910378

GO_REF:0000107

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

TANK-binding kinase 1

involved_in

ISO
IEA

(PMID:27129230)
GO_REF:0000107

PMID:27129230

GO_REF:0000107

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

Trim41

tripartite motif-containing 41

involved_in

ISO

(PMID:29760876)

PMID:29760876

NCBI chr10:33,676,348...33,687,432
Ensembl chr10:33,175,213...33,186,694

tripartite motif containing 56

involved_in

ISO

(PMID:29426904)

PMID:29426904

NCBI chr12:25,193,224...25,204,032
Ensembl chr12:19,551,521...19,567,462

Trim6

tripartite motif containing 6

involved_in

ISO
IEA

(PMID:24882218)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914

Ube2k

ubiquitin-conjugating enzyme E2K

involved_in

ISO
IEA

(PMID:24882218)
GO_REF:0000107

GO_REF:0000107

NCBI chr14:43,011,681...43,077,825
Ensembl chr14:42,658,016...42,718,630

Usp27x

ubiquitin specific peptidase 27, X-linked

involved_in

ISO

(PMID:31534008)

PMID:31534008

NCBI chr X:15,123,620...15,126,855
Ensembl chr X:15,124,596...15,125,912

Usp29

ubiquitin specific peptidase 29

involved_in

ISO
IEA

(PMID:32457395)
GO_REF:0000107

PMID:32457395

GO_REF:0000107

NCBI chr 1:66,874,216...67,097,731
Ensembl chr 1:66,874,017...67,097,686

Wnt5a

Wnt family member 5A

involved_in

ISO
IEA

(PMID:19399181)
GO_REF:0000107

PMID:19399181

GO_REF:0000107

NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234

Z-DNA binding protein 1

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

GO_REF:0000002
(PMID:17618271)
GO_REF:0000033

InterPro
RGD
GO_Central

PMID:17618271

GO_REF:0000002 GO_REF:0000033

NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:161,993,351...162,003,870

positive regulation of type II interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hpx

hemopexin

acts_upstream_of_or_within

ISO
IEA

MGI:2447193 (PMID:18641331)
GO_REF:0000107

PMID:18641331

GO_REF:0000107

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

immunity-related GTPase M

involved_in

ISO
IEA

(PMID:16888103)
GO_REF:0000107

PMID:16888103

GO_REF:0000107

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

Med1

mediator complex subunit 1

acts_upstream_of_or_within

ISO
IEA

MGI:2176946|MGI:3511276 (PMID:18339625)
GO_REF:0000107

PMID:18339625

GO_REF:0000107

NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,145,568...83,189,299

NLR family, CARD domain containing 5

involved_in

ISO

(PMID:20061403), (PMID:20639463)

PMID:20061403 PMID:20639463

NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121

Parp9

poly (ADP-ribose) polymerase family, member 9

involved_in

ISO
IEA
IBA

(PMID:27796300)
GO_REF:0000107
GO_REF:0000033

PMID:27796300

GO_REF:0000033 GO_REF:0000107

NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455

Txk

TXK tyrosine kinase

involved_in

ISO
IEA

(PMID:11859127)
GO_REF:0000107

PMID:11859127

GO_REF:0000107

NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448

protection from natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clec2d

C-type lectin domain family 2, member D

acts_upstream_of_or_within

ISO

MGI:107539 (PMID:12858173), (PMID:14990792), (PMID:19535641)

PMID:12858173 PMID:14990792 PMID:19535641

NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527

RT1 class Ia, locus A2

involved_in

ISO

(PMID:25631937), (PMID:9754572)

PMID:9754572 PMID:25631937

NCBI chr20:4,870,939...4,910,183

RT1-CE16

RT1 class I, locus CE16

NOT|involved_in

ISO

(PMID:18502829)
(PMID:18502829), (PMID:8839770)

PMID:8839770 PMID:18502829

NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563

RT1 class Ib, locus M3, gene 1

involved_in

ISO

(PMID:11290782)

PMID:11290782

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

Serpinb3a

serpin family B member 3A

involved_in

ISO

(PMID:21857942)

PMID:21857942

NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985

Serpinb9

serpin family B member 9

involved_in

ISO

(PMID:21795594)

PMID:21795594

NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230

Tap1

transporter 1, ATP binding cassette subfamily B member

IMP

RGD

PMID:8120379

RGD:2312378

NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901

Tap2

transporter 2, ATP binding cassette subfamily B member

IMP

RGD

PMID:8120379

RGD:2312378

NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407

regulation of antibacterial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Evpl

envoplakin

acts_upstream_of_or_within

ISO
IEA

MGI:1194898|MGI:96626 (PMID:27427436)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:101,458,227...101,474,778
Ensembl chr10:101,458,216...101,474,763

Ivl

involucrin

acts_upstream_of_or_within

ISO

MGI:107507|MGI:1194898 (PMID:27427436)

NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100

Ppl

periplakin

acts_upstream_of_or_within

ISO

MGI:107507|MGI:96626 (PMID:27427436)

NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575

regulation of antimicrobial humoral response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gata6

GATA binding protein 6

involved_in

ISO

(PMID:33082341)

PMID:33082341

NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532

Ppp2r3c

protein phosphatase 2, regulatory subunit B'', gamma

acts_upstream_of_or_within

ISO
IEA

MGI:3759678 (PMID:16129705)
GO_REF:0000107

PMID:16129705

GO_REF:0000107

NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491

regulation of complement activation, alternative pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cfh

complement factor H

involved_in

ISO

(PMID:20378178), (PMID:28671664)

PMID:20378178 PMID:28671664

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

regulation of cytoplasmic pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mir708

microRNA 708

involved_in

ISO

(PMID:31599428)

PMID:31599428

NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963

regulation of innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apoe

apolipoprotein E

involved_in

ISO

(PMID:29336888)

PMID:29336888

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

Appl1

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

involved_in

ISO

(PMID:27219021)

NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692

Appl2

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

involved_in

ISO
IEA

(PMID:27219021)
GO_REF:0000107

GO_REF:0000107

NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754

Casp8

caspase 8

involved_in

ISS
ISO

GO_REF:0000024
(PMID:32971525)

PMID:32971525

GO_REF:0000024

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542

Cd300a

Cd300a molecule

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

Cd300c2

CD300C molecule 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:100,253,312...100,258,553
Ensembl chr10:100,253,624...100,258,323

Cd300e

Cd300e molecule

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:100,289,729...100,309,996
Ensembl chr10:100,291,437...100,299,311

DEXH-box helicase 58

involved_in

ISO
IEA

(PMID:18411269)
GO_REF:0000107

PMID:18411269

GO_REF:0000107

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Dusp10

dual specificity phosphatase 10

acts_upstream_of_or_within

ISO
IEA

MGI:3052343 (PMID:15306813)
GO_REF:0000107

PMID:15306813

GO_REF:0000107

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716

Fgr

FGR proto-oncogene, Src family tyrosine kinase

involved_in

ISS
ISO

GO_REF:0000024
(PMID:21746961)

PMID:21746961

GO_REF:0000024

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

Igsf7

immunoglobulin superfamily, member 7

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:100,153,767...100,161,589
Ensembl chr10:100,156,238...100,182,647

Igsf7l1

immunoglobulin superfamily, member 7 like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr10:100,174,955...100,182,713
Ensembl chr10:100,156,238...100,182,647

Lrp8

LDL receptor related protein 8

involved_in

ISO
IEA

(PMID:29336888)
GO_REF:0000107

PMID:29336888

GO_REF:0000107

NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352

Myo1f

myosin IF

acts_upstream_of_or_within

ISO

MGI:3664779 (PMID:17023661)

PMID:17023661

NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911

N4bp1

Nedd4 binding protein 1

involved_in

ISO
IEA

(PMID:32971525)
GO_REF:0000107

PMID:32971525

GO_REF:0000107

NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570

Nfe2l2

NFE2 like bZIP transcription factor 2

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:16585964)

PMID:16585964

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

protein tyrosine phosphatase, non-receptor type 22

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

ring finger protein 135

involved_in

ISO
IBA
ISS

(PMID:19017631)
GO_REF:0000033
GO_REF:0000024

PMID:19017631

GO_REF:0000024 GO_REF:0000033

NCBI chr10:65,668,441...65,687,671
Ensembl chr10:65,170,560...65,262,804

Samhd1

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

involved_in

ISO
IEA
IBA

(PMID:19525956), (PMID:29670289)
GO_REF:0000107
GO_REF:0000033

PMID:19525956 PMID:29670289

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386

Serpinb1a

serpin family B member 1A

involved_in

ISO
IEA

(PMID:17664292)
GO_REF:0000107

PMID:17664292

GO_REF:0000107

NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102

TIR domain containing adaptor protein

involved_in

IEA

GO_REF:0000104

GO_REF:0000104

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Tkfc

triokinase and FMN cyclase

involved_in

ISO

(PMID:16289032)

PMID:16289032

NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737

triggering receptor expressed on myeloid cells 2

involved_in

ISO
IBA

(PMID:30548312)
GO_REF:0000033

PMID:30548312

GO_REF:0000033

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

three prime repair exonuclease 1

acts_upstream_of_or_within

ISO
IEA

(PMID:20871604), (PMID:26320659)
GO_REF:0000107

PMID:20871604 PMID:26320659

GO_REF:0000107

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

regulation of MyD88-dependent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

interferon regulatory factor 1

involved_in

ISS
ISO

GO_REF:0000024
(PMID:17018642)

PMID:17018642

GO_REF:0000024

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166

interferon regulatory factor 7

involved_in

ISO
IEA

(PMID:15800576)
GO_REF:0000107

PMID:15800576

GO_REF:0000107

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

regulation of MyD88-independent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

interferon regulatory factor 7

involved_in

ISO
IEA

(PMID:15800576)
GO_REF:0000107

PMID:15800576

GO_REF:0000107

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

regulation of natural killer cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Calhm6

calcium homeostasis modulator family member 6

involved_in

ISO
IEA

(PMID:36861806)
GO_REF:0000107

PMID:36861806

GO_REF:0000107

NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278

regulation of natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Klrb1

killer cell lectin like receptor B1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:162,456,294...162,474,989
Ensembl chr 4:162,456,294...162,474,989

Klrb1a

killer cell lectin like receptor B1A

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675

Klrb1b

killer cell lectin like receptor B1B

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:161,948,259...161,961,537
Ensembl chr 4:161,890,577...161,961,675

Klrb1c

killer cell lectin like receptor B1C

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:162,380,773...162,394,688
Ensembl chr 4:162,381,602...162,393,786

Lep

leptin

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:12504075)

PMID:12504075

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

Nkr-p1c

killer cell lectin-like receptor subfamily B member

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Pik3r6

phosphoinositide-3-kinase, regulatory subunit 6

involved_in

ISO
IEA
IBA

(PMID:11062502)
GO_REF:0000107
GO_REF:0000033

PMID:11062502

GO_REF:0000033 GO_REF:0000107

NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243

regulation of natural killer cell mediated immunity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RT1 class Ia, locus A2

involved_in

ISO

(PMID:18448674)

PMID:18448674

NCBI chr20:4,870,939...4,910,183

regulation of neutrophil mediated killing of gram-negative bacterium

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cxcl6

C-X-C motif chemokine ligand 6

acts_upstream_of_or_within

ISO

MGI:4819800 (PMID:20643340)

PMID:20643340

NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093

regulation of NLRP3 inflammasome complex assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Eif2ak2

eukaryotic translation initiation factor 2-alpha kinase 2

involved_in

ISS
ISO

GO_REF:0000024
(PMID:22801494)

PMID:22801494

GO_REF:0000024

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

Kcnk13

potassium two pore domain channel subfamily K member 13

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:35353387)
GO_REF:0000107

PMID:35353387

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:119,240,825...119,345,292
Ensembl chr 6:119,242,188...119,345,240

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc15a2

solute carrier family 15 member 2

involved_in

ISS
ISO

GO_REF:0000024
(PMID:29784761)

PMID:29784761

GO_REF:0000024

NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225

solute carrier family 15 member 4

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:29784761)

PMID:29784761

GO_REF:0000024 GO_REF:0000107

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Peli3

pellino E3 ubiquitin protein ligase family member 3

acts_upstream_of_or_within

ISO

(PMID:23892723)

PMID:23892723

NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:202,232,228...202,242,857

regulation of respiratory burst involved in inflammatory response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ncf1

neutrophil cytosolic factor 1

IMP

RGD

PMID:21275845

RGD:41404729

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

regulation of response to type II interferon

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Parp9

poly (ADP-ribose) polymerase family, member 9

involved_in

ISO
IEA

(PMID:16809771)
GO_REF:0000107

PMID:16809771

GO_REF:0000107

NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455

regulation of RIG-I signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nop53

NOP53 ribosome biogenesis factor

involved_in

ISO
IEA

(PMID:27824081)
GO_REF:0000107

PMID:27824081

GO_REF:0000107

NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902

regulation of toll-like receptor 3 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Flot2

flotillin 2

NOT|involved_in

ISO

(PMID:25204797)

NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756

Hcfc2

host cell factor C2

acts_upstream_of_or_within

ISO

MGI:5445585 (PMID:28970238)

PMID:28970238

NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801

Src

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

ISO

(PMID:37158982)

PMID:37158982

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

regulation of toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Appl1

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

involved_in

ISO

(PMID:27219021)

NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692

Appl2

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

involved_in

ISO
IEA

(PMID:27219021)
GO_REF:0000107

GO_REF:0000107

NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754

Flot1

flotillin 1

NOT|involved_in

ISO

(PMID:25204797)

NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978

Pik3r1

phosphoinositide-3-kinase regulatory subunit 1

involved_in

ISO

(PMID:19289601)

PMID:19289601

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

regulation of toll-like receptor 6 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

triggering receptor expressed on myeloid cells 2

involved_in

ISO

(PMID:31134514)

PMID:31134514

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

regulation of toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

amyloid beta precursor protein

involved_in

ISO

UniProtKB:P16671 (PMID:20037584)

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

Cd36

CD36 molecule

involved_in

ISO

UniProtKB:P05067-PRO_0000000092 (PMID:20037584)

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

Esr1

estrogen receptor 1

acts_upstream_of_or_within

ISO
IEA

MGI:2150897 (PMID:22659029)
GO_REF:0000107

PMID:22659029

GO_REF:0000107

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

Gfi1

growth factor independent 1 transcriptional repressor

involved_in

ISO
IEA

(PMID:20547752)
GO_REF:0000107

PMID:20547752

GO_REF:0000107

NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814

LOC681325

hypothetical protein LOC681325

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr X:74,312,698...74,316,311
Ensembl chr X:74,312,661...74,316,635

multifunctional ROCO family signaling regulator 1

involved_in

ISO
IEA

(PMID:20616063)
GO_REF:0000107

PMID:20616063

GO_REF:0000107

NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743

Mir146a

microRNA 146a

involved_in

ISO

(PMID:16885212)

PMID:16885212

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

TLR adaptor interacting with endolysosomal SLC15A4

involved_in

IEA

GO_REF:0000002

GO_REF:0000002

NCBI chr X:50,403,962...50,423,141
Ensembl chr X:50,361,248...50,423,269

regulation of type I interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cdc37

cell division cycle 37, HSP90 cochaperone

acts_upstream_of_or_within

ISO

(PMID:16280321)

PMID:16280321

NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809

regulation of type II interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cdc37

cell division cycle 37, HSP90 cochaperone

acts_upstream_of_or_within

ISO

(PMID:16280321)

PMID:16280321

NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809

response to type I interferon

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ch25h

cholesterol 25-hydroxylase

involved_in

ISO
ISS

(PMID:33239446)
GO_REF:0000024

PMID:33239446

GO_REF:0000024

NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195

Ikbke

inhibitor of nuclear factor kappa B kinase subunit epsilon

involved_in

ISO

(PMID:24882218)

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

Isg15

ISG15 ubiquitin-like modifier

involved_in

ISO
IEA

(PMID:22859821)
GO_REF:0000107

PMID:22859821

GO_REF:0000107

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

Setd2

SET domain containing 2, histone lysine methyltransferase

involved_in

ISO
IEA

(PMID:28753426)
GO_REF:0000107

PMID:28753426

GO_REF:0000107

NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489

Shfl

shiftless antiviral inhibitor of ribosomal frameshifting

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:26735137)

PMID:26735137

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:19,408,298...19,414,084
Ensembl chr 8:19,408,333...19,413,971

Shmt2

serine hydroxymethyltransferase 2

involved_in

ISO
IEA

(PMID:24075985)
GO_REF:0000107

PMID:24075985

GO_REF:0000107

NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236

Smpd1

sphingomyelin phosphodiesterase 1

involved_in

ISO
IEA

(PMID:20807762)
GO_REF:0000107

PMID:20807762

GO_REF:0000107

NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794

Sp100

SP100 nuclear antigen

involved_in

ISO

(PMID:15247905), (PMID:8810287), (PMID:9230084)
(PMID:16873258)

PMID:8810287 PMID:9230084 PMID:15247905 PMID:16873258

NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034

signal transducer and activator of transcription 1

involved_in

ISO

(PMID:24882218)

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

tripartite motif containing 56

involved_in

ISO

(PMID:21074459)

PMID:21074459

NCBI chr12:25,193,224...25,204,032
Ensembl chr12:19,551,521...19,567,462

response to type II interferon

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adamts13

ADAM metallopeptidase with thrombospondin type 1 motif, 13

IEP

RGD

PMID:18433458

RGD:2315954

NCBI chr 3:10,299,264...10,338,464
Ensembl chr 3:10,300,028...10,346,687

Bst2

bone marrow stromal cell antigen 2

involved_in

ISS
ISO

GO_REF:0000024
(PMID:21919738)

PMID:21919738

GO_REF:0000024

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

Calcoco2

calcium binding and coiled-coil domain 2

involved_in

ISO

(PMID:9230084)

PMID:9230084

NCBI chr10:81,055,467...81,069,298

Ccl5

C-C motif chemokine ligand 5

involved_in

IDA

PMID:10477596

BHF-UCL

PMID:10477596

RGD:8553666

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

Cd40

CD40 molecule

IEP

with tumor necrosis factor alpha

RGD

PMID:10403401

RGD:634252

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534

Cd74

CD74 molecule

involved_in

ISO

(PMID:32855215)

PMID:32855215

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

Cd86

CD86 molecule

IEP

RGD

PMID:16839612

RGD:2313438

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

class II, major histocompatibility complex, transactivator

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:16280321)
(PMID:32855215)
GO_REF:0000107

PMID:16280321 PMID:32855215

GO_REF:0000107

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

Cited1

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

involved_in

ISS
ISO

GO_REF:0000024
(PMID:9811838)

PMID:9811838

GO_REF:0000024

NCBI chr X:67,350,376...67,355,072
Ensembl chr X:67,350,373...67,355,162

Cxcl16

C-X-C motif chemokine ligand 16

involved_in

ISO
IEA

(PMID:18373975)
GO_REF:0000002

PMID:18373975

GO_REF:0000002

NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592

Cyp27b1

cytochrome P450, family 27, subfamily b, polypeptide 1

involved_in

ISO
IEA

(PMID:9282826)
GO_REF:0000107

PMID:9282826

GO_REF:0000107

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

Dnaja3

DnaJ heat shock protein family (Hsp40) member A3

involved_in

ISO

(PMID:11679576)

PMID:11679576

NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161

ENSRNOG00000068074

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 4:59,549,152...59,549,829

ENSRNOG00000070481

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 4:30,960,845...30,961,834

Gch1

GTP cyclohydrolase 1

involved_in

ISO

(PMID:12607127), (PMID:7678411), (PMID:9445252)

PMID:7678411 PMID:9445252 PMID:12607127

NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698

Gimap6

GTPase, IMAP family member 6

acts_upstream_of_or_within

ISO
IEA

(PMID:35551368)
GO_REF:0000107

PMID:35551368

GO_REF:0000107

NCBI chr 4:77,653,703...77,659,112
Ensembl chr 4:77,652,610...77,659,116

Gpr146

G protein-coupled receptor 146

acts_upstream_of_or_within

ISO
IEA

(PMID:28464285)
GO_REF:0000107

PMID:28464285

GO_REF:0000107

NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206

high mobility group box 1

IMP

RGD

PMID:18004227

RGD:2316773

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

Ifitm1

interferon induced transmembrane protein 1

involved_in

ISO
IBA

(PMID:21253575)
GO_REF:0000033

PMID:21253575

GO_REF:0000033

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

Ifitm2

interferon induced transmembrane protein 2

involved_in

ISO
IBA

(PMID:21253575)
GO_REF:0000033

PMID:21253575

GO_REF:0000033

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

Ifitm2-ps2

interferon induced transmembrane protein 2, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:68,187,131...68,187,808
Ensembl chr13:68,187,366...68,187,854

Ifitm3

interferon induced transmembrane protein 3

involved_in

ISO
IBA

(PMID:21253575)
GO_REF:0000033

PMID:21253575

GO_REF:0000033

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

Ifitm3-ps1

interferon induced transmembrane protein 3, pseudogene 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr14:61,233,269...61,233,688
Ensembl chr14:61,233,269...61,233,688

Ifitm3-ps2

interferon induced transmembrane protein 3, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr11:33,137,146...33,137,562
Ensembl chr11:33,137,146...33,138,061

Ifitm6

interferon induced transmembrane protein 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:196,117,043...196,118,315
Ensembl chr 1:196,117,049...196,118,386

Il23r

interleukin 23 receptor

involved_in

ISO

(PMID:12023369)

PMID:12023369

NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021

Kynu

kynureninase

involved_in

ISO

(PMID:9291104)

PMID:9291104

NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488

Lcn10

lipocalin 10

acts_upstream_of_or_within

ISO
IEA

(PMID:35757735)
GO_REF:0000107

PMID:35757735

GO_REF:0000107

NCBI chr 3:8,490,781...8,494,334
Ensembl chr 3:8,490,781...8,494,333

Mefv

MEFV innate immunity regulator, pyrin

involved_in

ISO
ISS

(PMID:26347139)
GO_REF:0000024

PMID:26347139

GO_REF:0000024

NCBI chr10:12,288,514...12,303,337
Ensembl chr10:11,787,422...11,796,973

Nub1

negative regulator of ubiquitin-like proteins 1

involved_in

ISO

(PMID:16707496)

PMID:16707496

NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694

RT1-Ba

RT1 class II, locus Ba

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

Sec61a1

SEC61 translocon subunit alpha 1

IEP

RGD

PMID:16604358

RGD:2312768

NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925

Shfl

shiftless antiviral inhibitor of ribosomal frameshifting

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:26735137)

PMID:26735137

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:19,408,298...19,414,084
Ensembl chr 8:19,408,333...19,413,971

Slc11a1

solute carrier family 11 member 1

acts_upstream_of_or_within

ISO
IEA

(PMID:9261342)
GO_REF:0000107

PMID:9261342

GO_REF:0000107

NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101

Slc22a5

solute carrier family 22 member 5

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:20722056)

PMID:20722056

GO_REF:0000024 GO_REF:0000107

NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309

Slc30a8

solute carrier family 30 member 8

IEP

RGD

PMID:19243577

RGD:2315023

NCBI chr 7:83,591,993...83,627,786
Ensembl chr 7:83,591,993...83,626,305

Snca

synuclein alpha

involved_in

ISO
IEA

(PMID:19157893)
GO_REF:0000107

PMID:19157893

GO_REF:0000107

NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262

Sp100

SP100 nuclear antigen

involved_in

ISO

(PMID:8810287), (PMID:9230084)

PMID:8810287 PMID:9230084

NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034

signal transducer and activator of transcription 1

involved_in

ISO

(PMID:11972023)

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

tripartite motif-containing 21

involved_in

ISO
IEA

(PMID:26347139)
GO_REF:0000107

PMID:26347139

GO_REF:0000107

NCBI chr 1:166,376,829...166,399,441
Ensembl chr 1:156,964,913...156,987,440

Ubd

ubiquitin D

involved_in

ISO
IBA

(PMID:17889673)
(PMID:16782901)
GO_REF:0000033

PMID:16782901 PMID:17889673

GO_REF:0000033

NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639

response to type III interferon

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Epg5

ectopic P-granules 5 autophagy tethering factor

acts_upstream_of_or_within

ISO
IEA

(PMID:34520306)
GO_REF:0000107

PMID:34520306

GO_REF:0000107

NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502

Shfl

shiftless antiviral inhibitor of ribosomal frameshifting

involved_in

ISO
IEA
ISS

(PMID:26735137)
GO_REF:0000107
GO_REF:0000024

PMID:26735137

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:19,408,298...19,414,084
Ensembl chr 8:19,408,333...19,413,971

RIG-I signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clpb

ClpB family mitochondrial disaggregase

involved_in

ISO

(PMID:31522117)

NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788

Lsm14a

LSM14A mRNA processing body assembly factor

acts_upstream_of_or_within

ISO
IEA

MGI:2442858|MGI:2444773 (PMID:22745163)
GO_REF:0000107

PMID:22745163

GO_REF:0000107

NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276

mitochondrial antiviral signaling protein

acts_upstream_of_or_within

ISO

MGI:1914320 (PMID:22745163)

PMID:22745163

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

2'-5'-oligoadenylate synthetase 3

involved_in

ISO
IEA

(PMID:30078389)
GO_REF:0000107

GO_REF:0000107

NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781

Phb1

prohibitin 1

involved_in

ISO

(PMID:31522117)

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

Phb2

prohibitin 2

involved_in

ISO
IEA

(PMID:31522117)
GO_REF:0000107

GO_REF:0000107

NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272

RNA sensor RIG-1

involved_in

ISO
IEA

(PMID:19211564), (PMID:28469175)
GO_REF:0000107

PMID:19211564 PMID:28469175

GO_REF:0000107

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

ring finger protein 135

involved_in

ISO
ISS

(PMID:23950712), (PMID:28469175), (PMID:31006531)
UniProtKB:Q8IUD6 (PMID:21147464), (PMID:28469175)
GO_REF:0000024

PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531

GO_REF:0000024

NCBI chr10:65,668,441...65,687,671
Ensembl chr10:65,170,560...65,262,804

tripartite motif-containing 25

NOT|involved_in

ISO

(PMID:31006531)

PMID:31006531

NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257

stimulatory C-type lectin receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clec4a

C-type lectin domain family 4, member A

involved_in

ISO

(PMID:22041900)

PMID:22041900

NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402

Clec6a-ps1

C-type lectin domain family 6, member A, pseudogene 1

involved_in

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 4:156,539,408...156,559,032
Ensembl chr 4:156,539,408...156,558,605
Ensembl chr 4:156,539,408...156,558,605

C-type lectin domain containing 7A

involved_in

ISO

(PMID:19136564)

PMID:19136564

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

Klrc1

killer cell lectin like receptor C1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425

killer cell lectin like receptor C2

involved_in

ISO

(PMID:9655483)

NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843

RGD
GO_Central
Ensembl
UniProt

killer cell lectin like receptor D1

involved_in

ISO
IBA
IEA
ISS

(PMID:9655483)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518

killer cell lectin like receptor E1

involved_in
acts_upstream_of_or_within

IBA
IEA

GO_REF:0000033
GO_REF:0000107

GO_Central
Ensembl

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638

Klrh1

killer cell lectin-like receptor subfamily H, member 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,288,228...163,301,977
Ensembl chr 4:163,288,229...163,300,535

Klri1

killer cell lectin-like receptor family I member 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870

Klri2

killer cell lectin-like receptor family I member 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484

killer cell lectin like receptor K1

acts_upstream_of_or_within

ISO

(PMID:12645935)

PMID:12645935

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

phospholipase C, gamma 2

involved_in

ISO

(PMID:19136564), (PMID:22041900)

PMID:19136564 PMID:22041900

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Syk

spleen associated tyrosine kinase

involved_in

IEA
ISO

GO_REF:0000107
(PMID:19136564)

PMID:19136564

GO_REF:0000107

NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410

Tyrobp

transmembrane immune signaling adaptor Tyrobp

involved_in

ISO
IEA
ISS

(PMID:9655483)
GO_REF:0000107
GO_REF:0000024

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

stimulatory killer cell immunoglobulin-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tyrobp

transmembrane immune signaling adaptor Tyrobp

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:9655483)

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

suppression of symbiont entry into host

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Zg16

zymogen granule protein 16

acts_upstream_of_or_within

ISO
IEA

MGI:3529206 (PMID:27849619)
GO_REF:0000107

PMID:27849619

GO_REF:0000107

NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079

susceptibility to natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cadm1

cell adhesion molecule 1

involved_in

ISS
IEA
ISO
IBA

GO_REF:0000024
GO_REF:0000107
(PMID:15811952)
GO_REF:0000033

HGNC
Ensembl
RGD
GO_Central

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:47,847,325...48,182,833

nectin cell adhesion molecule 2

involved_in

ISO
IEA

(PMID:12913096)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

ISO

(PMID:12913096)

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

Ulbp1

UL16 binding protein 1

acts_upstream_of_or_within

ISO

(PMID:12645935)

PMID:12645935

NCBI chr 1:1,694,255...1,716,160

symbiont-induced defense-related programmed cell death

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Janus kinase 2

acts_upstream_of_or_within

ISO
IEA

(PMID:12426001)
GO_REF:0000107

PMID:12426001

GO_REF:0000107

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

TIRAP-dependent toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TIR domain containing adaptor protein

involved_in

ISO

(PMID:11544529)

PMID:11544529

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

toll-like receptor 2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

high mobility group box 1

involved_in

ISO

(PMID:14660645)

PMID:14660645

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

interleukin-1 receptor-associated kinase 1

involved_in
acts_upstream_of_or_within

ISO
IEA
IBA

(PMID:10383454)
GO_REF:0000107
GO_REF:0000033
(PMID:10549626)

PMID:10383454 PMID:10549626

GO_REF:0000033 GO_REF:0000107

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

galectin 9

NOT|involved_in

ISO

(PMID:16116184)

PMID:16116184

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

nucleotide-binding oligomerization domain containing 2

acts_upstream_of

ISO

MGI:2680581 (PMID:15220916)

PMID:15220916

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

phosphoinositide-3-kinase adaptor protein 1

involved_in

ISO
IEA

(PMID:22187460)
GO_REF:0000107

PMID:22187460

GO_REF:0000107

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

receptor-interacting serine-threonine kinase 2

acts_upstream_of_or_within

ISO
IEA

(PMID:11894098)
GO_REF:0000107

PMID:11894098

GO_REF:0000107

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

toll-like receptor 2

involved_in

ISO

(PMID:17128265)

PMID:17128265

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

Tnip2

TNFAIP3 interacting protein 2

involved_in

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
(PMID:16633345)

PMID:16633345

GO_REF:0000033 GO_REF:0000107

NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265

toll-like receptor 3 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd86

CD86 molecule

involved_in

ISO

(PMID:25158758)

PMID:25158758

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

Colec12

collectin sub-family member 12

involved_in

ISO

(PMID:25204797)

NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618

hepatitis A virus cellular receptor 2

involved_in

ISO

(PMID:22842346)

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

galectin 9

involved_in

IMP

PMID:25158758

UniProt

PMID:25158758

RGD:10054077

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

2'-5' oligoadenylate synthetase 1A

involved_in

ISO

(PMID:30078389)

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

Rftn1

raftlin lipid raft linker 1

acts_upstream_of_or_within

ISO

(PMID:21266579)

PMID:21266579

NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084

Rnf170

ring finger protein 170

acts_upstream_of_or_within

ISO
IEA

(PMID:31076723)
GO_REF:0000107

PMID:31076723

GO_REF:0000107

NCBI chr16:72,631,638...72,656,893
Ensembl chr16:65,928,895...65,954,083

Scara3

scavenger receptor class A, member 3

NOT|involved_in

ISO

(PMID:25204797)

NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894

SLP adaptor and CSK interacting membrane protein

involved_in

ISO

(PMID:28098138)

NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171

TIR domain containing adaptor molecule 1

involved_in

ISO

(PMID:12471095)

PMID:12471095

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

toll-like receptor 3

involved_in

ISO
IEA

(PMID:17128265), (PMID:18172197)
GO_REF:0000107

PMID:17128265 PMID:18172197

GO_REF:0000107

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

Tnf

tumor necrosis factor

involved_in

IMP

PMID:25158758

UniProt

PMID:25158758

RGD:10054077

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tnip2

TNFAIP3 interacting protein 2

involved_in

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
(PMID:16633345)

PMID:16633345

GO_REF:0000033 GO_REF:0000107

NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265

unc-93 homolog B1, TLR signaling regulator

involved_in

ISO
IEA
IBA

(PMID:18082565)
GO_REF:0000107
(PMID:16415873)
GO_REF:0000033

PMID:16415873 PMID:18082565

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338

toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD14 molecule

involved_in

ISO
IBA

(PMID:27986454)
GO_REF:0000033

PMID:27986454

GO_REF:0000033

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261

Chuk

component of inhibitor of nuclear factor kappa B kinase complex

involved_in

ISO
IEA

(PMID:26189595)
GO_REF:0000107

PMID:26189595

GO_REF:0000107

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Ecsit

ECSIT signaling integrator

involved_in

ISO
IEA

(PMID:25371197)
GO_REF:0000107

PMID:25371197

GO_REF:0000107

NCBI chr 8:20,605,583...20,618,453
Ensembl chr 8:20,605,583...20,618,390

high mobility group box 1

involved_in

ISO

(PMID:14660645)

PMID:14660645

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

interleukin-1 receptor-associated kinase 1

acts_upstream_of_or_within
involved_in

ISO
IBA

(PMID:10549626)
GO_REF:0000033

PMID:10549626

GO_REF:0000033

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Irak2

interleukin-1 receptor-associated kinase 2

involved_in

ISO
IEA

(PMID:17878161)
GO_REF:0000107

PMID:17878161

GO_REF:0000107

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

interferon regulatory factor 3

involved_in

ISO
IEA

(PMID:25636800)
GO_REF:0000107

PMID:25636800

GO_REF:0000107

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

Letmd1

LETM1 domain containing 1

acts_upstream_of_or_within

ISO
IEA

(PMID:31980577)
GO_REF:0000107

PMID:31980577

GO_REF:0000107

NCBI chr 7:131,584,241...131,597,797
Ensembl chr 7:131,584,259...131,597,796

galectin 9

NOT|involved_in

ISO

(PMID:16116184)

PMID:16116184

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

Ly96

lymphocyte antigen 96

involved_in

ISO
IBA

(PMID:24380872)
GO_REF:0000033

PMID:24380872

GO_REF:0000033

NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386

LYN proto-oncogene, Src family tyrosine kinase

involved_in

ISO
IEA

(PMID:28098138)
GO_REF:0000107

GO_REF:0000107

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Map3k7

mitogen activated protein kinase kinase kinase 7

involved_in

ISO
IEA

(PMID:25371197)
GO_REF:0000107

PMID:25371197

GO_REF:0000107

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

MYD88, innate immune signal transduction adaptor

involved_in

ISO
IEA
IBA

(PMID:16751103)
GO_REF:0000107
GO_REF:0000033

PMID:16751103

GO_REF:0000033 GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

Naglu

N-acetyl-alpha-glucosaminidase

acts_upstream_of_or_within

ISO
IEA

MGI:1934018 (PMID:29624734)
GO_REF:0000107

PMID:29624734

GO_REF:0000107

NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972

Nfkbia

NFKB inhibitor alpha

involved_in
acts_upstream_of_or_within

ISO

(PMID:7479976)
(PMID:18261938)

PMID:7479976 PMID:18261938

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

N-myc (and STAT) interactor

involved_in

ISO

(PMID:29038465)

NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498

2'-5' oligoadenylate synthetase 1A

involved_in

ISO

(PMID:30078389)

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

phosphoinositide-3-kinase adaptor protein 1

involved_in

ISO
IEA

(PMID:22187458), (PMID:22187460)
GO_REF:0000107

PMID:22187458 PMID:22187460

GO_REF:0000107

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

RELA proto-oncogene, NF-kB subunit

involved_in

ISO
IEA

(PMID:25355951)
GO_REF:0000107

PMID:25355951

GO_REF:0000107

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

receptor-interacting serine-threonine kinase 2

acts_upstream_of_or_within

ISO
IEA

MGI:2660793 (PMID:11894098)
GO_REF:0000107

PMID:11894098

GO_REF:0000107

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

S100a14

S100 calcium binding protein A14

involved_in

ISO
IEA

(PMID:17625598)
GO_REF:0000107

PMID:17625598

GO_REF:0000107

NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:176,008,395...176,010,423

SLP adaptor and CSK interacting membrane protein

involved_in

ISO

(PMID:28098138)

NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171

TANK-binding kinase 1

involved_in

ISO
IEA

(PMID:28747347)
GO_REF:0000107

PMID:28747347

GO_REF:0000107

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

TIR domain containing adaptor molecule 1

involved_in

ISO

(PMID:12471095)

PMID:12471095

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

TIR domain containing adaptor molecule 2

involved_in

ISO

(PMID:28630139)

PMID:28630139

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

TIR domain containing adaptor protein

involved_in

ISO
IBA

(PMID:16751103)
(PMID:11526399)
GO_REF:0000033

PMID:11526399 PMID:16751103

GO_REF:0000033

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

PMID:10196138 PMID:15618008 PMID:18222170 PMID:25549946 PMID:28098138

toll-like receptor 4

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

GO_REF:0000107
(PMID:28098138)
(PMID:25549946)
GO_REF:0000033
(PMID:10196138), (PMID:15618008), (PMID:18222170)

Ensembl
RGD
GO_Central

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tmem126a

transmembrane protein 126A

acts_upstream_of_or_within

ISO
IEA

(PMID:25549946)
GO_REF:0000107

PMID:25549946

GO_REF:0000107

NCBI chr 1:144,424,481...144,430,730
Ensembl chr 1:144,422,703...144,430,628

Tnip3

TNFAIP3 interacting protein 3

involved_in

ISO

(PMID:17088249)

PMID:17088249

NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605

Traf3

Tnf receptor-associated factor 3

involved_in

ISO
IEA

(PMID:18222170)
GO_REF:0000107

PMID:18222170

GO_REF:0000107

NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:130,206,484...130,305,481

TNF receptor associated factor 6

involved_in

ISO

(PMID:25371197)

PMID:25371197

NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507

Tril

TLR4 interactor with leucine-rich repeats

involved_in

ISO
IEA
IBA

(PMID:19710467)
GO_REF:0000107
GO_REF:0000033

PMID:19710467

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172

toll-like receptor 5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MYD88, innate immune signal transduction adaptor

involved_in

ISO
IEA

(PMID:16751103)
GO_REF:0000107

PMID:16751103

GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

TIR domain containing adaptor protein

NOT|involved_in

ISO

(PMID:12447442)

PMID:12447442

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Tlr5

toll-like receptor 5

involved_in

ISO

(PMID:14625549), (PMID:17128265)

PMID:14625549 PMID:17128265

NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738

toll-like receptor 7 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

hepatitis A virus cellular receptor 2

involved_in

ISO

(PMID:22842346)

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

phosphoinositide-3-kinase adaptor protein 1

involved_in

ISO
IEA

(PMID:22187458)
GO_REF:0000107

PMID:22187458

GO_REF:0000107

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

SLP adaptor and CSK interacting membrane protein

involved_in

ISO

(PMID:28098138)

NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171

toll-like receptor 7

involved_in

ISO
IEA
IBA

(PMID:12032557)
GO_REF:0000107
GO_REF:0000033
(PMID:14976261)

PMID:12032557 PMID:14976261

GO_REF:0000033 GO_REF:0000107

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

unc-93 homolog B1, TLR signaling regulator

involved_in

ISO
IEA
IBA

(PMID:19006693)
GO_REF:0000107
(PMID:16415873)
GO_REF:0000033

PMID:16415873 PMID:19006693

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338

toll-like receptor 8 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MYD88, innate immune signal transduction adaptor

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:33718825)

PMID:33718825

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

toll-like receptor 7

involved_in

ISO
IEA

(PMID:12032557)
GO_REF:0000107

PMID:12032557

GO_REF:0000107

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

toll-like receptor 8

involved_in

ISO

(PMID:12032557), (PMID:24942581), (PMID:33718825)

PMID:12032557 PMID:24942581 PMID:33718825

NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549

toll-like receptor 9 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Epg5

ectopic P-granules 5 autophagy tethering factor

acts_upstream_of_positive_effect

ISO
IEA

(PMID:29130391)
GO_REF:0000107

PMID:29130391

GO_REF:0000107

NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502

hepatitis A virus cellular receptor 2

involved_in

ISO

(PMID:22842346)

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

Nr1h4

nuclear receptor subfamily 1, group H, member 4

involved_in

IEA
ISO

GO_REF:0000107
(PMID:23372731)

PMID:23372731

GO_REF:0000107

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

phosphoinositide-3-kinase adaptor protein 1

involved_in

ISO
IEA

(PMID:22187458), (PMID:22187460)
GO_REF:0000107

PMID:22187458 PMID:22187460

GO_REF:0000107

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

toll-like receptor 9

involved_in

ISO
IEA

(PMID:23857366)
GO_REF:0000107

PMID:23857366

GO_REF:0000107

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Tnip2

TNFAIP3 interacting protein 2

involved_in

ISO
IEA

(PMID:16633345)
GO_REF:0000107

PMID:16633345

GO_REF:0000107

NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265

unc-93 homolog B1, TLR signaling regulator

involved_in

ISO
IEA
IBA

(PMID:19006693)
GO_REF:0000107
(PMID:16415873), (PMID:38169466)
GO_REF:0000033

PMID:16415873 PMID:19006693 PMID:38169466

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338

toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ap3b1

adaptor related protein complex 3 subunit beta 1

acts_upstream_of_or_within

ISO

(PMID:20847273)

PMID:20847273

NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935

Bcl10

BCL10, immune signaling adaptor

involved_in

ISO
IEA

(PMID:16831874)
GO_REF:0000107

GO_REF:0000107

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

Cd86

CD86 molecule

acts_upstream_of_or_within

ISO

(PMID:19734906)

PMID:19734906

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

Fosl1

FOS like 1, AP-1 transcription factor subunit

acts_upstream_of_or_within

ISO

MGI:3055991 (PMID:30990796)

PMID:30990796

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

Irak3

interleukin-1 receptor-associated kinase 3

ISO

PMID:27832756

RGD:34888235

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

LOC100360522

ribosomal protein P1-like

acts_upstream_of_negative_effect

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr17:8,436,843...8,437,954
Ensembl chr17:8,431,465...8,435,348
Ensembl chr 8:8,431,465...8,435,348

Lrrc19

leucine rich repeat containing 19

acts_upstream_of_or_within
involved_in

ISO
IEA
IBA

(PMID:19679103)
GO_REF:0000107
GO_REF:0000033

PMID:19679103

GO_REF:0000033 GO_REF:0000107

NCBI chr 5:109,494,891...109,507,948
Ensembl chr 5:109,497,121...109,507,938

Ly96

lymphocyte antigen 96

involved_in

ISO
IEA

(PMID:14607928)
GO_REF:0000107

PMID:14607928

GO_REF:0000107

NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386

Mapkapk2

MAPK activated protein kinase 2

involved_in

IBA
IEA
ISO

GO_REF:0000033
GO_REF:0000107
(PMID:17906627)

UniProt
Ensembl
RGD
GO_Central

PMID:17906627

GO_REF:0000033 GO_REF:0000107

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

Mapkapk3

MAPK activated protein kinase 3

involved_in

ISS
IEA
ISO
IBA

GO_REF:0000024
GO_REF:0000107
(PMID:17906627)
GO_REF:0000033

PMID:17906627

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568

Nfkbiz

NFKB inhibitor zeta

involved_in

ISO

MGI:3046930|MGI:5501251 (PMID:23728777), (PMID:25124037)

PMID:23728777 PMID:25124037

NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723

phospholipase C, gamma 2

involved_in

ISO

(PMID:19136564)

PMID:19136564

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Ptgs2os

prostaglandin-endoperoxide synthase 2, opposite strand

acts_upstream_of

ISO

(PMID:23907535)

PMID:23907535

NCBI chr13:62,160,002...62,163,710

Rplp1

ribosomal protein lateral stalk subunit P1

acts_upstream_of_negative_effect

IEA

GO_REF:0000107

GO_REF:0000107

NCBI chr 8:71,289,539...71,290,872
Ensembl chr 8:62,393,177...62,395,339

Rps6ka3

ribosomal protein S6 kinase A3

involved_in

ISO
IEA

(PMID:17906627)
GO_REF:0000107

PMID:17906627

GO_REF:0000107

NCBI chr X:35,517,306...35,623,296
Ensembl chr X:35,517,306...35,623,207

TIR domain containing adaptor molecule 1

involved_in

ISO

(PMID:12471095)

PMID:12471095

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

Tifab

TIFA inhibitor

acts_upstream_of_negative_effect

ISO

MGI:5911664 (PMID:26458771)

Ensembl
InterPro
GO_Central
RGD

PMID:26458771

NCBI chr17:8,438,622...8,441,750
Ensembl chr17:8,431,635...8,436,592

Tlr1

toll-like receptor 1

involved_in

IDA
IEA
IBA
ISO

GO_REF:0000107
GO_REF:0000002
GO_REF:0000033
(PMID:16893894)

PMID:16893894 PMID:16973131

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1643119

NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125

Tlr10

toll-like receptor 10

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033

NCBI chr14:43,400,843...43,414,056
Ensembl chr14:43,406,217...43,413,917

Tlr11

toll-like receptor 11

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr15:23,545,408...23,549,849
Ensembl chr15:23,545,408...23,549,849

Tlr12

toll-like receptor 12

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:140,961,166...140,964,171
Ensembl chr 5:140,959,996...140,964,816

UniProt
InterPro
GO_Central
RGD

toll-like receptor 2

involved_in

IDA
IEA
IBA
ISO
IMP

GO_REF:0000104
GO_REF:0000002
GO_REF:0000033
(PMID:16893894)

PMID:16893894 PMID:16973131 PMID:18353287

GO_REF:0000002 GO_REF:0000033 GO_REF:0000104, RGD:1643119, RGD:5684896

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

PMID:18172197 PMID:16973131

toll-like receptor 3

involved_in

IDA
IEA
IBA
ISO

GO_REF:0000107
GO_REF:0000033
(PMID:18172197)

Ensembl
GO_Central
RGD

GO_REF:0000033 GO_REF:0000107, RGD:1643119

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

PMID:14607928 PMID:16973131

toll-like receptor 4

involved_in

IDA
IEA
ISO

GO_REF:0000107
GO_REF:0000002
(PMID:14607928)

Ensembl
InterPro
RGD

GO_REF:0000002 GO_REF:0000107, RGD:1643119

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tlr5

toll-like receptor 5

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033

NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738

PMID:16973131 PMID:18353287

toll-like receptor 6

involved_in

IDA
IEA
IBA
IMP

GO_REF:0000002
GO_REF:0000033

InterPro
GO_Central
RGD

GO_REF:0000002 GO_REF:0000033, RGD:1643119, RGD:5684896

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

toll-like receptor 7

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

toll-like receptor 8

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549

PMID:17128265 PMID:16973131

toll-like receptor 9

involved_in

IDA
IEA
IBA
ISO

GO_REF:0000107
GO_REF:0000033
(PMID:17128265)

Ensembl
GO_Central
RGD

GO_REF:0000033 GO_REF:0000107, RGD:1643119

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Traf3

Tnf receptor-associated factor 3

involved_in

ISO
IEA

(PMID:16306937)
GO_REF:0000107
(PMID:18222170)

PMID:16306937 PMID:18222170

GO_REF:0000107

NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:130,206,484...130,305,481

unc-93 homolog B1, TLR signaling regulator

acts_upstream_of_or_within
involved_in

ISO
IEA

MGI:3619211 (PMID:16415873)
GO_REF:0000107
GO_REF:0000002

RGD
Ensembl
InterPro

PMID:16415873

GO_REF:0000002 GO_REF:0000107

NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338

toll-like receptor TLR1:TLR2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLP adaptor and CSK interacting membrane protein

involved_in

ISO

(PMID:28098138)

NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171

toll-like receptor TLR6:TLR2 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MYD88, innate immune signal transduction adaptor

involved_in

ISO
IEA

(PMID:36964784)
GO_REF:0000107

PMID:36964784

GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

RELA proto-oncogene, NF-kB subunit

involved_in

ISO
IEA

(PMID:27708357)
GO_REF:0000107

PMID:27708357

GO_REF:0000107

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

toll-like receptor 2

involved_in

ISO

(PMID:23626692)

PMID:23626692

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

toll-like receptor 6

involved_in

ISO
IEA

(PMID:23626692)
GO_REF:0000107

PMID:23626692

GO_REF:0000107

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

TRAM-dependent toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Prkce

protein kinase C, epsilon

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:16757566)
GO_REF:0000107

PMID:16757566

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Rab11fip2

RAB11 family interacting protein 2

involved_in

ISO
IEA

(PMID:30883606)
GO_REF:0000107

PMID:30883606

GO_REF:0000107

NCBI chr 1:258,950,535...259,094,555
Ensembl chr 1:258,923,873...259,093,752

TIR domain containing adaptor molecule 2

involved_in

ISO

(PMID:22685567)
(PMID:19412184)

PMID:19412184 PMID:22685567

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

TRIF-dependent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd274

CD274 molecule

involved_in

ISO

(PMID:36232715)

PMID:36232715

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

Cd300lf

Cd300 molecule-like family member F

involved_in

ISO
ISS

(PMID:22043923)
GO_REF:0000024

PMID:22043923

GO_REF:0000024

NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041

interferon regulatory factor 3

involved_in

ISO
IEA

(PMID:25636800)
GO_REF:0000107

PMID:25636800

GO_REF:0000107

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

PMID:17658277 PMID:25636800

TIR domain containing adaptor molecule 1

involved_in

ISO
IEA
IBA

(PMID:25636800)
GO_REF:0000002
GO_REF:0000033
(PMID:17658277)

RGD
InterPro
GO_Central

GO_REF:0000002 GO_REF:0000033

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

TIR domain containing adaptor molecule 2

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

toll-like receptor 4

involved_in

IEA
ISO

GO_REF:0000107
UniProtKB:Q9EPW9 (PMID:20037584)

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

toll-like receptor 6

involved_in

ISO
IEA

UniProtKB:Q9QUK6 (PMID:20037584)
GO_REF:0000107

GO_REF:0000107

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

type I interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cr2

complement C3d receptor 2

involved_in

ISO

(PMID:1849076)

PMID:1849076

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

ENSRNOG00000065554

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 5:103,321,196...103,322,285

ENSRNOG00000068074

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 4:59,549,152...59,549,829

ENSRNOG00000070481

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

Ensembl chr 4:30,960,845...30,961,834

Gpr108

G protein-coupled receptor 108

acts_upstream_of_or_within

ISO
IEA

(PMID:37330913)
GO_REF:0000107

PMID:37330913

GO_REF:0000107

NCBI chr 9:2,120,740...2,131,771
Ensembl chr 9:2,120,744...2,132,572

Hdac4

histone deacetylase 4

involved_in

ISO

(PMID:31127039)

PMID:31127039

NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:92,507,611...92,750,164

Ifi27

interferon, alpha-inducible protein 27

involved_in

ISO

(PMID:27777077)

PMID:27777077

NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294

interferon induced with helicase C domain 1

acts_upstream_of_or_within

ISO
IEA

MGI:3663677 (PMID:28031478)
GO_REF:0000107

GO_REF:0000107

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

Ifitm1

interferon induced transmembrane protein 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

Ifitm2

interferon induced transmembrane protein 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

Ifitm2-ps2

interferon induced transmembrane protein 2, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr13:68,187,131...68,187,808
Ensembl chr13:68,187,366...68,187,854

Ifitm3

interferon induced transmembrane protein 3

involved_in
acts_upstream_of_or_within

IBA
ISO

GO_REF:0000033
(PMID:20064371)

PMID:20064371

GO_REF:0000033

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

Ifitm3-ps1

interferon induced transmembrane protein 3, pseudogene 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr14:61,233,269...61,233,688
Ensembl chr14:61,233,269...61,233,688

Ifitm3-ps2

interferon induced transmembrane protein 3, pseudogene 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr11:33,137,146...33,137,562
Ensembl chr11:33,137,146...33,138,061

Ifitm6

interferon induced transmembrane protein 6

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:196,117,043...196,118,315
Ensembl chr 1:196,117,049...196,118,386

Ifna1

interferon, alpha 1

involved_in

ISO
IBA

(PMID:24784232)
GO_REF:0000033

PMID:24784232

GO_REF:0000033

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

Ifna4

interferon, alpha 4

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052

Ifna4l1

interferon, alpha 4 like 1

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302

Ifna5

interferon, alpha 5

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,187,852...103,188,430

Ifnar1

interferon alpha and beta receptor subunit 1

involved_in

ISO
IBA

(PMID:21854986), (PMID:7665574)
(PMID:14532120), (PMID:23872679), (PMID:27129230)
GO_REF:0000033

PMID:7665574 PMID:14532120 PMID:21854986 PMID:23872679 PMID:27129230

GO_REF:0000033

NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979

Ifnar2

interferon alpha and beta receptor subunit 2

involved_in

ISO
IBA

(PMID:21854986), (PMID:26424569), (PMID:7665574)
GO_REF:0000033

PMID:7665574 PMID:21854986 PMID:26424569

GO_REF:0000033

NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124

Ifnb1

interferon beta 1

involved_in

ISO
IBA

(PMID:18035482), (PMID:33581076)
GO_REF:0000033
(PMID:27129230)

PMID:18035482 PMID:27129230 PMID:33581076

GO_REF:0000033

NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523

Ifnk

interferon kappa

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281

interleukin-1 receptor-associated kinase 1

involved_in

ISO
IEA

(PMID:23633945)
GO_REF:0000107

PMID:23633945

GO_REF:0000107

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

interferon regulatory factor 3

involved_in

ISO

(PMID:27129230)

PMID:27129230

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

interferon regulatory factor 7

involved_in

ISO
IEA

(PMID:27129230)
GO_REF:0000107

PMID:27129230

GO_REF:0000107

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

Jak1

Janus kinase 1

involved_in

ISO
IEA

(PMID:7532278), (PMID:8232552)
GO_REF:0000107

PMID:7532278 PMID:8232552

GO_REF:0000107

NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926

LOC120103158

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,378,576...103,379,147
Ensembl chr 5:103,378,593...103,379,147

LOC120103159

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,407,135...103,407,884
Ensembl chr 5:103,407,283...103,407,837

LOC120103160

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,426,092...103,427,016
Ensembl chr 5:103,426,387...103,426,941

LOC120103161

interferon alpha-12-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,441,204...103,442,180
Ensembl chr 5:103,441,540...103,442,094

LOC120103162

interferon alpha-1-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 5:103,455,380...103,455,934
Ensembl chr 5:103,455,380...103,455,934

MYD88, innate immune signal transduction adaptor

involved_in

ISO
IEA

(PMID:23633945)
GO_REF:0000107

PMID:23633945

GO_REF:0000107

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

2'-5' oligoadenylate synthetase 1A

involved_in

ISO
IBA

(PMID:28640813)
GO_REF:0000033

PMID:28640813

GO_REF:0000033

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

Oas1b

2-5 oligoadenylate synthetase 1B

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242

Oas1d

2'-5' oligoadenylate synthetase 1D

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,648,583...35,658,037
Ensembl chr12:35,648,583...35,657,902

Oas1e

2'-5' oligoadenylate synthetase 1E

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,750,359...35,759,304
Ensembl chr12:35,750,359...35,759,301

Oas1h

2 ' -5 ' oligoadenylate synthetase 1H

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,682,862...35,695,717
Ensembl chr12:35,683,699...35,693,366

Oas1i

2 ' -5 ' oligoadenylate synthetase 1I

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604

Oas2

2'-5' oligoadenylate synthetase 2

involved_in

ISS
IBA
ISO

GO_REF:0000024
GO_REF:0000033
(PMID:29117179)

UniProt
GO_Central
RGD

PMID:29117179

GO_REF:0000024 GO_REF:0000033

NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371

2'-5'-oligoadenylate synthetase 3

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781

2'-5'-oligoadenylate synthetase-like

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641

Oasl2

2'-5' oligoadenylate synthetase-like 2

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr12:41,710,072...41,722,687
Ensembl chr12:41,709,435...41,722,547

Sin3a

SIN3 transcription regulator family member A

involved_in

ISO
IEA

(PMID:22783022)
GO_REF:0000107

PMID:22783022

GO_REF:0000107

NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192

signal transducer and activator of transcription 1

involved_in

ISO
IBA

(PMID:23386060)
(PMID:12138178), (PMID:24598055)
GO_REF:0000033

PMID:12138178 PMID:23386060 PMID:24598055

GO_REF:0000033

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

Stat2

signal transducer and activator of transcription 2

involved_in

ISO
IEA
IBA

(PMID:23391734), (PMID:31836668), (PMID:32092142)
GO_REF:0000107
(PMID:24598055), (PMID:28165510)
GO_REF:0000033

PMID:23391734 PMID:24598055 PMID:28165510 PMID:31836668 PMID:32092142

GO_REF:0000033 GO_REF:0000107

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

Stat4

signal transducer and activator of transcription 4

involved_in

IBA

GO_REF:0000033

GO_REF:0000033

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

three prime repair exonuclease 1

acts_upstream_of_or_within

ISO
IEA

MGI:3052754 (PMID:28351661)
GO_REF:0000107

PMID:28351661

GO_REF:0000107

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

tripartite motif-containing 65

acts_upstream_of_or_within

ISO

MGI:6356825 (PMID:28031478)

NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971

Tyk2

tyrosine kinase 2

involved_in

ISO

(PMID:8232552)

PMID:8232552

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

type II interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

class II, major histocompatibility complex, transactivator

involved_in

ISO

(PMID:19041327)

PMID:19041327

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

Hpx

hemopexin

acts_upstream_of

ISO
IEA

MGI:2447193 (PMID:18641331)
GO_REF:0000107

PMID:18641331

GO_REF:0000107

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

Ifng

interferon gamma

involved_in

IDA
ISO

PMID:20624457
UniProtKB:P05067|UniProtKB:P10636|UniProtKB:P49768 (PMID:16914093), (PMID:19808651), (PMID:22504299), (PMID:23629966)
(PMID:23629966)

PMID:16914093 PMID:19808651 PMID:22504299 PMID:23629966 PMID:20624457

RGD:8554478

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Ifngr1

interferon gamma receptor 1

involved_in

ISO
IEA

(PMID:28883123)
GO_REF:0000002

PMID:28883123

GO_REF:0000002

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

Ifngr2

interferon gamma receptor 2

involved_in

IEA

GO_REF:0000108

GOC

GO_REF:0000108

NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005

interferon regulatory factor 1

involved_in

ISS
ISO

GO_REF:0000024
(PMID:21909274)

PMID:21909274

GO_REF:0000024

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166

Jak1

Janus kinase 1

involved_in

ISO
IEA

(PMID:8232552)
GO_REF:0000107

PMID:8232552

GO_REF:0000107

NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926

Janus kinase 2

involved_in

IMP

PMID:11536325

BHF-UCL

PMID:11536325

RGD:8553830

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

signal transducer and activator of transcription 1

involved_in

ISO

(PMID:21268089), (PMID:26479788)
(PMID:12138178)

PMID:12138178 PMID:21268089 PMID:26479788

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

Tp53

tumor protein p53

involved_in

IEA
ISO

GO_REF:0000107
(PMID:23629966)

PMID:23629966

GO_REF:0000107

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524

Tyk2

tyrosine kinase 2

involved_in

ISO

(PMID:8232552)

PMID:8232552

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

type III interferon-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ifng

interferon gamma

involved_in

ISO

(PMID:16914093)

PMID:16914093

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Ifngr1

interferon gamma receptor 1

involved_in

ISO

(PMID:20015550)

PMID:20015550

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

Ifngr2

interferon gamma receptor 2

involved_in

ISO
IEA

(PMID:20015550)
GO_REF:0000107