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ONTOLOGY REPORT - ANNOTATIONS

Term:antiviral innate immune response
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Accession:GO:0140374 term browser browse the term
Definition:A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.


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antiviral innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31522117)		 UniProt
Ensembl
RGD		 PMID:31522117 GO_REF:0000024 GO_REF:0000107 NCBI chr10:74,118,232...74,151,366
Ensembl chr10:73,621,883...73,653,896 		JBrowse link
G Atad3a ATPase family, AAA domain containing 3A involved_in ISO
IEA
ISS		 (PMID:31522117)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31522117 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:171,632,545...171,652,725
Ensembl chr 5:166,350,304...166,370,482 		JBrowse link
G Clpb ClpB family mitochondrial disaggregase involved_in ISO (PMID:31522117) RGD PMID:31522117 NCBI chr 1:165,440,705...165,563,514
Ensembl chr 1:156,028,930...156,168,788 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Dhx15 DEAH-box helicase 15 involved_in ISO
IEA		 (PMID:24990078)
GO_REF:0000107
(PMID:26494172), (PMID:34678144)		 RGD
Ensembl		 PMID:24990078 PMID:26494172 PMID:34678144 GO_REF:0000107 NCBI chr14:62,999,886...63,037,829
Ensembl chr14:58,787,127...58,825,088 		JBrowse link
G Dhx16 DEAH-box helicase 16 involved_in ISO
IEA		 (PMID:35263596)
GO_REF:0000107		 RGD
Ensembl		 PMID:35263596 GO_REF:0000107 NCBI chr20:2,866,804...2,879,790
Ensembl chr20:2,862,000...2,874,948 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Dus2 dihydrouridine synthase 2 involved_in ISO UniProtKB:P19525 (PMID:18096616) RGD PMID:18096616 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22948139)		 Ensembl
RGD		 PMID:22948139 GO_REF:0000107 NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Hcfc2 host cell factor C2 acts_upstream_of_or_within ISO MGI:5445585 (PMID:28970238) RGD PMID:28970238 NCBI chr 7:22,875,440...22,907,391
Ensembl chr 7:20,991,017...21,019,801 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:3663677 (PMID:28031478)		 GO_Central
Ensembl
RGD		 PMID:28031478 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:19416887)
GO_REF:0000107
(PMID:31390091)		 RGD
Ensembl		 PMID:19416887 PMID:31390091 GO_REF:0000107 NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 involved_in ISO (PMID:21642987) RGD PMID:21642987 NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:9891032) RGD PMID:9891032 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Marchf2 membrane associated ring-CH-type finger 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:32935379)		 UniProt
Ensembl
RGD		 PMID:32935379 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:27992402) RGD PMID:27992402 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:35102342) RGD PMID:35102342 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Morc3 MORC family CW-type zinc finger 3 involved_in ISO
IEA		 (PMID:27440897)
GO_REF:0000107		 RGD
Ensembl		 PMID:27440897 GO_REF:0000107 NCBI chr11:46,621,575...46,664,315
Ensembl chr11:33,152,025...33,194,646 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA		 (PMID:18835251)
GO_REF:0000107		 RGD
Ensembl		 PMID:18835251 GO_REF:0000107 NCBI chr 8:109,897,723...109,958,247
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO (PMID:33093214) RGD PMID:33093214 NCBI chr10:56,277,134...56,332,229
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26494172), (PMID:34678144)
GO_REF:0000107
(PMID:34161762)		 UniProt
RGD
Ensembl		 PMID:26494172 PMID:34161762 PMID:34678144 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,434,484...205,441,245
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Nmb neuromedin B involved_in ISO (PMID:31601264) RGD PMID:31601264 NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:134,869,446...134,872,190 		JBrowse link
G Nmbr neuromedin B receptor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31601264)		 UniProt
Ensembl
RGD		 PMID:31601264 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:10,942,476...10,966,174
Ensembl chr 1:9,134,889...9,145,462 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas1b 2-5 oligoadenylate synthetase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242 		JBrowse link
G Oas1d 2'-5' oligoadenylate synthetase 1D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,648,583...35,658,037
Ensembl chr12:35,648,583...35,657,902 		JBrowse link
G Oas1e 2'-5' oligoadenylate synthetase 1E involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,750,359...35,759,304
Ensembl chr12:35,750,359...35,759,301 		JBrowse link
G Oas1h 2 ' -5 ' oligoadenylate synthetase 1H involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,682,862...35,695,717
Ensembl chr12:35,683,699...35,693,366 		JBrowse link
G Oas1i 2 ' -5 ' oligoadenylate synthetase 1I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,464,568...41,492,036
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Oasl2 2'-5' oligoadenylate synthetase-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,710,072...41,722,687
Ensembl chr12:41,709,435...41,722,547 		JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO (PMID:36943869) RGD PMID:36943869 NCBI chr19:45,141,043...45,184,136
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
G Pde12 phosphodiesterase 12 involved_in ISO
IEA		 (PMID:15231837)
GO_REF:0000107		 RGD
Ensembl		 PMID:15231837 GO_REF:0000107 NCBI chr16:1,926,807...1,932,383
Ensembl chr16:1,915,386...1,925,887 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:31522117) RGD PMID:31522117 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO
IEA		 (PMID:31522117)
GO_REF:0000107		 RGD
Ensembl		 PMID:31522117 GO_REF:0000107 NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26454002)		 Ensembl
RGD		 PMID:26454002 GO_REF:0000107 NCBI chr 3:81,982,669...82,002,028
Ensembl chr 3:61,575,447...61,594,347 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO
IEA		 (PMID:38114488)
GO_REF:0000107		 RGD
Ensembl		 PMID:38114488 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO
IEA
IBA		 (PMID:28469175)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:28469175 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Rnf135 ring finger protein 135 involved_in ISO
ISS		 (PMID:28469175), (PMID:31006531)
(PMID:21147464), (PMID:23950712)
GO_REF:0000024		 RGD
UniProt		 PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531 GO_REF:0000024 NCBI chr10:65,668,441...65,687,671
Ensembl chr10:65,170,560...65,262,804 		JBrowse link
G Rpsa ribosomal protein SA involved_in ISO (PMID:38114488) RGD PMID:38114488 NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G Senp7 SUMO specific peptidase 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28095500)		 UniProt
RGD		 PMID:28095500 GO_REF:0000024 NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711 		JBrowse link
G Serinc3 serine incorporator 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26416733), (PMID:26416734), (PMID:37474505)		 Ensembl
RGD		 PMID:26416733 PMID:26416734 PMID:37474505 GO_REF:0000107 NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:152,301,772...152,321,808 		JBrowse link
G Serinc5 serine incorporator 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26416733), (PMID:26416734), (PMID:37474505)		 UniProt
RGD		 PMID:26416733 PMID:26416734 PMID:37474505 GO_REF:0000024 NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346 		JBrowse link
G Smarca5 SNF2 related chromatin remodeling ATPase 5 involved_in ISO
IEA		 (PMID:38114488)
GO_REF:0000107		 RGD
Ensembl		 PMID:38114488 GO_REF:0000107 NCBI chr19:44,172,465...44,208,967
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA		 (PMID:21074459)
GO_REF:0000107		 RGD
Ensembl		 PMID:21074459 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA		 (PMID:14703513), (PMID:22394562)
GO_REF:0000107		 RGD
Ensembl		 PMID:14703513 PMID:22394562 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Tmem120a transmembrane protein 120A involved_in ISO
IEA		 (PMID:35013224)
GO_REF:0000107		 RGD
Ensembl		 PMID:35013224 GO_REF:0000107 NCBI chr12:20,942,243...20,950,908
Ensembl chr12:20,942,439...20,990,316 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA		 (PMID:11773383)
GO_REF:0000107		 RGD
Ensembl		 PMID:11773383 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 acts_upstream_of_or_within ISO MGI:5795738 (PMID:31390091) RGD PMID:31390091 NCBI chr13:107,223,499...107,248,358
Ensembl chr13:104,694,805...104,719,673 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:18984593) RGD PMID:18984593 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trim21 tripartite motif-containing 21 involved_in ISO
IEA		 (PMID:36943869)
GO_REF:0000107		 RGD
Ensembl		 PMID:36943869 GO_REF:0000107 NCBI chr 1:166,376,829...166,399,441
Ensembl chr 1:156,964,913...156,987,440 		JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO
IEA		 (PMID:17392790)
GO_REF:0000107		 RGD
Ensembl		 PMID:17392790 GO_REF:0000107 NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257 		JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO
IEA		 (PMID:27992402)
GO_REF:0000107		 RGD
Ensembl		 PMID:27992402 GO_REF:0000107 NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO
IEA		 (PMID:35263596)
GO_REF:0000107		 RGD
Ensembl		 PMID:35263596 GO_REF:0000107 NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Trim65 tripartite motif-containing 65 acts_upstream_of_or_within ISO MGI:6356825|MGI:6356826|MGI:6356827 (PMID:28031478) RGD PMID:28031478 NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971 		JBrowse link
G Trim7 tripartite motif-containing 7 involved_in ISO (PMID:35893676) RGD PMID:35893676 NCBI chr10:33,205,491...33,221,482
Ensembl chr10:33,205,491...33,221,468 		JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 involved_in ISO (PMID:36603579) RGD PMID:36603579 NCBI chr13:84,875,719...84,910,706
Ensembl chr13:82,342,946...82,377,469
Ensembl chr 6:82,342,946...82,377,469 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:35893676) RGD PMID:35893676 NCBI chr 7:32,041,190...32,071,252
Ensembl chr 7:30,154,616...30,184,355 		JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W involved_in ISO (PMID:35893676) RGD PMID:35893676 NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965 		JBrowse link
G Ubl7 ubiquitin-like 7 involved_in ISO
IEA		 (PMID:36943869)
GO_REF:0000107		 RGD
Ensembl		 PMID:36943869 GO_REF:0000107 NCBI chr 8:58,321,279...58,340,353
Ensembl chr 8:58,320,866...58,340,344 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:27801882) RGD PMID:27801882 NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Usp20 ubiquitin specific peptidase 20 involved_in ISO
IEA		 (PMID:27801882)
GO_REF:0000107		 RGD
Ensembl		 PMID:27801882 GO_REF:0000107 NCBI chr 3:34,670,613...34,704,156
Ensembl chr 3:14,272,908...14,306,409 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO
IEA		 (PMID:31968013)
GO_REF:0000107		 RGD
Ensembl		 PMID:31968013 GO_REF:0000107 NCBI chr 7:30,251,142...30,301,185
Ensembl chr 7:28,364,033...28,410,053 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISO (PMID:34192517) RGD PMID:34192517 NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
G Zdhhc1 zinc finger, DHHC-type containing 1 involved_in ISO
IBA		 (PMID:25299331)
GO_REF:0000033		 RGD
GO_Central		 PMID:25299331 GO_REF:0000033 NCBI chr19:50,260,445...50,285,634
Ensembl chr19:33,350,533...33,375,616 		JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 involved_in ISO
IBA		 (PMID:29429998)
GO_REF:0000033		 RGD
GO_Central		 PMID:29429998 GO_REF:0000033 NCBI chr 1:31,124,900...31,156,075
Ensembl chr 1:29,296,334...29,326,898 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      immune response 2236
        innate immune response 1025
          antiviral innate immune response 69
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to biotic stimulus 1943
        response to external biotic stimulus 1894
          response to other organism 1890
            defense response to other organism 1336
              defense response to symbiont 1112
                innate immune response 1025
                  antiviral innate immune response 69
paths to the root