ONTOLOGY REPORT - ANNOTATIONS
Term: P-type transmembrane transporter activity
Accession: GO:0140358
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Definition: Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and Pi, the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol.
Synonyms: exact_synonym: E1-E2 ATPase; P-type ATPase
xref: TC:3.A.3; Wikipedia:P-type_ATPase
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Atp13a1
ATPase 13A1
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936596:1,842,469...1,859,379
Ensembl chrNW_004936596:1,842,480...1,859,389
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Atp13a3
ATPase 13A3
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936711:325,978...400,374
Ensembl chrNW_004936711:354,020...397,145
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Atp13a4
ATPase 13A4
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936711:1,151,847...1,275,517
Ensembl chrNW_004936711:1,151,943...1,275,518
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Atp13a5
ATPase 13A5
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936711:1,294,974...1,402,797
Ensembl chrNW_004936711:1,294,892...1,402,793
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Anxa5
annexin A5
ISO
RGD
PMID:9299392
RGD:10053703
NCBI chrNW_004936662:926,302...959,964
Ensembl chrNW_004936662:925,940...939,451
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Atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
enables
ISO IEA
RGD UniProt Ensembl RHEA InterPro
PMID:12222829 PMID:12409282
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 RGD:724593 RGD:727704
NCBI chrNW_004936501:11,818,301...11,836,221
Ensembl chrNW_004936501:11,816,585...11,836,231
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Atp2a2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
enables
ISO IEA
RGD Ensembl UniProt InterPro RHEA
PMID:12409282 PMID:21300842
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 RGD:6904139 RGD:724593
NCBI chrNW_004936558:3,300,941...3,357,595
Ensembl chrNW_004936558:3,300,941...3,357,941
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Atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
enables
IEA
InterPro UniProt Ensembl RHEA
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116
NCBI chrNW_004936677:552,066...585,093
Ensembl chrNW_004936677:551,933...585,114
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Atp2b1
ATPase plasma membrane Ca2+ transporting 1
enables
IEA
UniProt TreeGrafter InterPro RHEA
GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 GO_REF:0000118
NCBI chrNW_004936507:6,525,302...6,631,003
Ensembl chrNW_004936507:6,523,199...6,630,606
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Atp2b2
ATPase plasma membrane Ca2+ transporting 2
enables
ISO IEA
RGD TreeGrafter UniProt RHEA InterPro
PMID:2837461
GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 GO_REF:0000118 RGD:631720
NCBI chrNW_004936602:2,744,757...3,011,051
Ensembl chrNW_004936602:2,744,759...3,007,940
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Atp2b3
ATPase plasma membrane Ca2+ transporting 3
enables
IEA
RHEA TreeGrafter InterPro UniProt
GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 GO_REF:0000118
NCBI chrNW_004936809:396,883...466,372
Ensembl chrNW_004936809:396,733...466,524
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Atp2b4
ATPase plasma membrane Ca2+ transporting 4
enables
ISO IEA
RGD TreeGrafter UniProt InterPro RHEA Ensembl
PMID:11779484
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:628395
NCBI chrNW_004936567:944,825...1,039,920
Ensembl chrNW_004936567:950,797...993,245
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Atp2c1
ATPase secretory pathway Ca2+ transporting 1
enables NOT|enables
ISO IEA
(PMID:16192278)
RGD InterPro Ensembl UniProt RHEA UniProt
PMID:15328051 PMID:16192278 PMID:19527224
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 RGD:1581800 RGD:7241224
NCBI chrNW_004936529:4,340,131...4,474,884
Ensembl chrNW_004936529:4,361,424...4,474,436
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Atp2c2
ATPase secretory pathway Ca2+ transporting 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936641:3,498,693...3,547,968
Ensembl chrNW_004936641:3,498,693...3,547,968
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Atp2a2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936558:3,300,941...3,357,595
Ensembl chrNW_004936558:3,300,941...3,357,941
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Atp2b2
ATPase plasma membrane Ca2+ transporting 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936602:2,744,757...3,011,051
Ensembl chrNW_004936602:2,744,759...3,007,940
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Atp2b3
ATPase plasma membrane Ca2+ transporting 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936809:396,883...466,372
Ensembl chrNW_004936809:396,733...466,524
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Atp7a
ATPase copper transporting alpha
enables
ISO
(PMID:15634671)
MGI
PMID:15634671
NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040
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Atp7b
ATPase copper transporting beta
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936565:4,694,294...4,763,661
Ensembl chrNW_004936565:4,694,281...4,763,773
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Atp13a1
ATPase 13A1
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936596:1,842,469...1,859,379
Ensembl chrNW_004936596:1,842,480...1,859,389
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Atp13a2
ATPase cation transporting 13A2
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936474:3,968,216...3,980,821
Ensembl chrNW_004936474:3,968,506...3,980,815
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Atp13a4
ATPase 13A4
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936711:1,151,847...1,275,517
Ensembl chrNW_004936711:1,151,943...1,275,518
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Atp13a5
ATPase 13A5
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936711:1,294,974...1,402,797
Ensembl chrNW_004936711:1,294,892...1,402,793
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Tmem94
transmembrane protein 94
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936594:695,180...729,723
Ensembl chrNW_004936594:695,175...730,999
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Atp2c1
ATPase secretory pathway Ca2+ transporting 1
enables
IEA
RHEA Ensembl
GO_REF:0000107 GO_REF:0000116
NCBI chrNW_004936529:4,340,131...4,474,884
Ensembl chrNW_004936529:4,361,424...4,474,436
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Atp2c2
ATPase secretory pathway Ca2+ transporting 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936641:3,498,693...3,547,968
Ensembl chrNW_004936641:3,498,693...3,547,968
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Atp7a
ATPase copper transporting alpha
enables
IEA
UniProt Ensembl
GO_REF:0000003 GO_REF:0000107
NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040
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Atp7b
ATPase copper transporting beta
enables
IEA
UniProt
GO_REF:0000003
NCBI chrNW_004936565:4,694,294...4,763,661
Ensembl chrNW_004936565:4,694,281...4,763,773
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Atp12a
ATPase H+/K+ transporting non-gastric alpha2 subunit
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936720:2,363,933...2,378,426
Ensembl chrNW_004936720:2,363,933...2,378,426
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
enables
IEA
InterPro Ensembl
GO_REF:0000002 GO_REF:0000107
NCBI chrNW_004936627:1,555,151...1,584,370
Ensembl chrNW_004936627:1,554,873...1,584,638
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936740:489,357...514,235
Ensembl chrNW_004936740:488,154...514,308
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Atp1a3
ATPase Na+/K+ transporting subunit alpha 3
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936706:476,473...494,659
Ensembl chrNW_004936706:477,107...495,525
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LOC101966280
sodium/potassium-transporting ATPase subunit alpha-4
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004936740:445,952...478,580
Ensembl chrNW_004936740:445,952...478,532
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Atp12a
ATPase H+/K+ transporting non-gastric alpha2 subunit
contributes_to enables
ISO IEA
RGD UniProt Ensembl
PMID:16046397
GO_REF:0000003 GO_REF:0000107 RGD:2301240
NCBI chrNW_004936720:2,363,933...2,378,426
Ensembl chrNW_004936720:2,363,933...2,378,426
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Atp4a
ATPase H+/K+ transporting subunit alpha
enables
IEA
InterPro TreeGrafter Ensembl UniProt
GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936570:802,170...815,023
Ensembl chrNW_004936570:802,170...814,056
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Atp12a
ATPase H+/K+ transporting non-gastric alpha2 subunit
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936720:2,363,933...2,378,426
Ensembl chrNW_004936720:2,363,933...2,378,426
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
enables
ISO IEA
RGD TreeGrafter Ensembl
PMID:12531906 PMID:16624992 PMID:16893515
GO_REF:0000107 GO_REF:0000118 RGD:1581763 RGD:2302992 RGD:629542
NCBI chrNW_004936627:1,555,151...1,584,370
Ensembl chrNW_004936627:1,554,873...1,584,638
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
enables
ISO IEA
RGD TreeGrafter Ensembl
PMID:16624992
GO_REF:0000107 GO_REF:0000118 RGD:2302992
NCBI chrNW_004936740:489,357...514,235
Ensembl chrNW_004936740:488,154...514,308
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Atp1a3
ATPase Na+/K+ transporting subunit alpha 3
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936706:476,473...494,659
Ensembl chrNW_004936706:477,107...495,525
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Atp1b1
ATPase Na+/K+ transporting subunit beta 1
enables
ISO IEA
RGD Ensembl
PMID:16624992
GO_REF:0000107 RGD:2302992
NCBI chrNW_004936481:17,438,146...17,460,329
Ensembl chrNW_004936481:17,436,270...17,460,348
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Atp1b2
ATPase Na+/K+ transporting subunit beta 2
ISO
RGD
PMID:12562669
RGD:631758
NCBI chrNW_004936595:908,019...914,426
Ensembl chrNW_004936595:907,919...915,053
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Atp1b3
ATPase Na+/K+ transporting subunit beta 3
ISO
RGD
PMID:12562669 PMID:16624992
RGD:2302992 RGD:631758
NCBI chrNW_004936540:3,621,656...3,640,885
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Atp4a
ATPase H+/K+ transporting subunit alpha
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004936570:802,170...815,023
Ensembl chrNW_004936570:802,170...814,056
G
LOC101966280
sodium/potassium-transporting ATPase subunit alpha-4
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936740:445,952...478,580
Ensembl chrNW_004936740:445,952...478,532
G
Atp1a3
ATPase Na+/K+ transporting subunit alpha 3
enables
ISO
(PMID:19376779)
BHF-UCL
PMID:19376779
NCBI chrNW_004936706:476,473...494,659
Ensembl chrNW_004936706:477,107...495,525
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