ONTOLOGY REPORT - ANNOTATIONS
Term: molecular sequestering activity
Accession: GO:0140313
browse the term
Definition: Binding to a specific molecule to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
Synonyms: xref: Reactome:R-HSA-203553 "eNOS binds NOSIP"; Reactome:R-HSA-203680 "eNOS:NOSIP translocation from caveolae to intracellular compartments"; Reactome:R-HSA-3245898 "TCN1 binds correnoids in the circulation"
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C1r
complement C1r
enables
ISO
(PMID:20178990)
RGD
PMID:20178990
NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
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Calr
calreticulin
enables
ISO
(PMID:35948544)
RGD
PMID:35948544
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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Cd69
Cd69 molecule
enables
ISO
(PMID:37039481)
RGD
PMID:37039481
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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Epn1
Epsin 1
enables
ISO
ChEBI:18348 (PMID:11161217)
RGD
PMID:11161217
NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874
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Gopc
golgi associated PDZ and coiled-coil motif containing
enables
ISO
(PMID:11707463)
RGD
PMID:11707463
NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903
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Hspbp1
HSPA (Hsp70) binding protein 1
enables
ISO
(PMID:21247889)
RGD
PMID:21247889
NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593
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Nfkbia
NFKB inhibitor alpha
enables
ISO
(PMID:7479976)
RGD
PMID:7479976
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nosip
nitric oxide synthase interacting protein
enables
ISO
UniProtKB:P29476 (PMID:15548660)
RGD
PMID:15548660
NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650
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Prdx4
peroxiredoxin 4
enables
ISO IEA
(PMID:21916849) GO_REF:0000107
RGD Ensembl
PMID:21916849
GO_REF:0000107
NCBI chr X:40,026,762...40,044,066
Ensembl chr X:40,026,651...40,044,066
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Sqstm1
sequestosome 1
enables
ISO
(PMID:31281713)
RGD
PMID:31281713
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Tnfaip8
TNF alpha induced protein 8
enables
ISO
(PMID:28740220)
RGD
PMID:28740220
NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517
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Trim15
tripartite motif containing 15
enables
ISO
(PMID:34871740)
RGD
PMID:34871740
NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249
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Tssc4
tumor suppressing subtransferable candidate 4
enables
ISO IEA ISS
(PMID:35188580) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:35188580
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:198,251,986...198,254,810
Ensembl chr 1:198,235,487...198,254,980
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Ttr
transthyretin
enables
ISO
MGI:1857264 (PMID:11036082)
RGD
PMID:11036082
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Usp9x
ubiquitin specific peptidase 9, X-linked
enables
ISO
(PMID:25552655)
RGD
PMID:25552655
NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711
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Wdr44
WD repeat domain 44
enables
ISO ISS
(PMID:31204173) GO_REF:0000024
RGD UniProt
PMID:31204173
GO_REF:0000024
NCBI chr X:114,481,890...114,587,307
Ensembl chr X:114,482,006...114,587,224
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Xaf1
XIAP associated factor 1
enables
ISO
(PMID:36394357)
RGD
PMID:36394357
NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770
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Casq2
calsequestrin 2
enables
ISO IEA
(PMID:16908766), (PMID:21416293) GO_REF:0000107 (PMID:16932808)
RGD Ensembl
PMID:16908766 PMID:16932808 PMID:21416293
GO_REF:0000107
NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267
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Fth1
ferritin heavy chain 1
enables
ISO
(PMID:9924025)
RGD
PMID:9924025
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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Lcn2
lipocalin 2
enables
ISS ISO
GO_REF:0000024 (PMID:27780864)
UniProt RGD
PMID:27780864
GO_REF:0000024
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Myt1l
myelin transcription factor 1-like
enables
EXP IDA
PMID:10606515
DisProt
PMID:10606515 PMID:10606515
RGD:12793025 , RGD:12793025
NCBI chr 6:46,164,742...46,564,234
Ensembl chr 6:46,428,150...46,561,671
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Castor1
cytosolic arginine sensor for mTORC1 subunit 1
enables
ISS ISO
GO_REF:0000024 (PMID:33594058)
UniProt RGD
PMID:33594058
GO_REF:0000024
NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
enables
ISO
(PMID:11595739)
RGD
PMID:11595739
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Ctnnd1
catenin delta 1
enables
ISO
(PMID:21998202)
RGD
PMID:21998202
NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
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Ddx56
DEAD-box helicase 56
enables
ISO
(PMID:31340999)
RGD
PMID:31340999
NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333
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Impact
impact RWD domain protein
enables
ISS ISO
GO_REF:0000024 (PMID:24333428)
UniProt RGD
PMID:24333428
GO_REF:0000024
NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569
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Insig1
insulin induced gene 1
enables
ISO
(PMID:15899885), (PMID:32322062)
RGD
PMID:15899885 PMID:32322062
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Insig2
insulin induced gene 2
enables
ISO IEA
(PMID:15899885), (PMID:32322062) GO_REF:0000107
RGD Ensembl
PMID:15899885 PMID:32322062
GO_REF:0000107
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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Kifbp
kinesin family binding protein
enables
ISO IEA
(PMID:33252036) GO_REF:0000107
RGD Ensembl
PMID:33252036
GO_REF:0000107
NCBI chr20:30,512,899...30,532,504
Ensembl chr20:30,512,901...30,532,476
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Laptm5
lysosomal protein transmembrane 5
enables
ISO
(PMID:18619870)
RGD
PMID:18619870
NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
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Lrrc15
leucine rich repeat containing 15
enables
IEA ISO
GO_REF:0000107 (PMID:36228039), (PMID:36735681), (PMID:36757924)
Ensembl RGD
PMID:36228039 PMID:36735681 PMID:36757924
GO_REF:0000107
NCBI chr11:70,469,817...70,484,268
Ensembl chr11:70,469,804...70,484,267
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Nck1
NCK adaptor protein 1
enables
ISO
(PMID:38614099)
RGD
PMID:38614099
NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
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Nfkb1
nuclear factor kappa B subunit 1
enables
ISO
(PMID:1423592)
RGD
PMID:1423592
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkbia
NFKB inhibitor alpha
enables
ISS IBA ISO
GO_REF:0000024 GO_REF:0000033 (PMID:1493333), (PMID:7628694), (PMID:7796813), (PMID:7878466)
UniProt GO_Central RGD
PMID:1493333 PMID:7628694 PMID:7796813 PMID:7878466
GO_REF:0000024 GO_REF:0000033
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Pmepa1
prostate transmembrane protein, androgen induced 1
enables
ISO
(PMID:20129061)
RGD
PMID:20129061
NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454
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Rbck1
RANBP2-type and C3HC4-type zinc finger containing 1
enables
ISO
(PMID:16083853)
RGD
PMID:16083853
NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
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Sdcbp
syndecan binding protein
enables
ISO
(PMID:25893292)
RGD
PMID:25893292
NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
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Sec14l1
SEC14-like lipid binding 1
enables
ISO
(PMID:23843640)
RGD
PMID:23843640
NCBI chr10:102,319,920...102,367,070
Ensembl chr10:102,319,920...102,367,068
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Sesn2
sestrin 2
enables
ISO
(PMID:26586190), (PMID:35114100)
RGD
PMID:26586190 PMID:35114100
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Sfn
stratifin
enables
ISO
(PMID:37797010)
RGD
PMID:37797010
NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
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Smad6
SMAD family member 6
enables
ISO
(PMID:33667543)
RGD
PMID:33667543
NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
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Smo
smoothened, frizzled class receptor
enables
ISS ISO IEA
GO_REF:0000024 (PMID:33886552) GO_REF:0000107
UniProt RGD Ensembl
PMID:33886552
GO_REF:0000024 GO_REF:0000107
NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
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Spi1
Spi-1 proto-oncogene
enables
ISO
(PMID:29924977)
RGD
PMID:29924977
NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
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Sqstm1
sequestosome 1
enables
ISS ISO
GO_REF:0000024 (PMID:37306101)
UniProt RGD
PMID:37306101
GO_REF:0000024
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Tarbp2
Tarbp2 subunit of RISC loading complex
enables
ISO
(PMID:30927622)
RGD
PMID:30927622
NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
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Tmc8
transmembrane channel-like 8
enables
ISO
(PMID:23429285)
RGD
PMID:23429285
NCBI chr10:103,000,038...103,010,601
Ensembl chr10:102,998,402...103,010,590
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Tmsb4x
thymosin beta 4, X-linked
enables
ISO
(PMID:21343177)
RGD
PMID:21343177
NCBI chr X:27,144,666...27,146,667
Ensembl chr X:27,128,610...27,146,667 Ensembl chr10:27,128,610...27,146,667
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Usp38
ubiquitin specific peptidase 38
enables
ISO
(PMID:34102342)
RGD
PMID:34102342
NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437
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Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
enables
ISO
(PMID:11118213), (PMID:22797923)
RGD
PMID:11118213 PMID:22797923
NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
enables
ISS ISO
GO_REF:0000024 (PMID:36732624), (PMID:38377992)
UniProt RGD
PMID:36732624 PMID:38377992
GO_REF:0000024
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
enables
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:18439900), (PMID:35662396)
UniProt Ensembl RGD
PMID:18439900 PMID:35662396
GO_REF:0000024 GO_REF:0000107
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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Trem1
triggering receptor expressed on myeloid cells 1
enables
ISO
(PMID:26561551)
RGD
PMID:26561551
NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
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Stat3
signal transducer and activator of transcription 3
enables
ISO IEA
(PMID:31507089) GO_REF:0000107
RGD Ensembl
PMID:31507089
GO_REF:0000107
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Zar1
zygote arrest 1
enables
ISS ISO
GO_REF:0000024 (PMID:36264786)
UniProt RGD
PMID:36264786
GO_REF:0000024
NCBI chr14:35,193,446...35,197,382
Ensembl chr14:35,193,446...35,197,382
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Slc39a4
solute carrier family 39 member 4
enables
ISO IEA
(PMID:25882556), (PMID:30793391) GO_REF:0000107
RGD Ensembl
PMID:25882556 PMID:30793391
GO_REF:0000107
NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553
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