Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:small molecule sensor activity
go back to main search page
Accession:GO:0140299 term browser browse the term
Definition:Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.
Synonyms:exact_synonym: small molecular sensor activity;   small molecule sensing activity



show annotations for term's descendants           Sort by:
small molecule sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 enables ISO (PMID:26972053) RGD PMID:26972053 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 enables ISS
ISO
GO_REF:0000024
(MGI:7388221|PMID:18403674)
(PMID:16407889), (PMID:18403674), (PMID:18604214)
UniProt
RGD
PMID:16407889 PMID:18403674 PMID:18604214 GO_REF:0000024 MGI:7388221 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
amino acid sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sar1a secretion associated, Ras related GTPase 1A enables ISO (PMID:34290409) RGD PMID:34290409 NCBI chr20:29,623,529...29,635,935
Ensembl chr20:29,623,553...29,635,935
JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B enables ISO (PMID:34290409) RGD PMID:34290409 NCBI chr10:36,024,415...36,054,069
Ensembl chr10:36,024,382...36,054,066
JBrowse link
ATP-dependent DNA damage sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmc1 DNA meiotic recombinase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:111,124,888...111,167,465
Ensembl chr 7:111,124,888...111,167,952
JBrowse link
G Mlh1 mutL homolog 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mlh3 mutL homolog 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:104,881,483...104,917,686
Ensembl chr 6:104,881,483...104,917,728
JBrowse link
G Msh2 mutS homolog 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh4 mutS homolog 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:242,785,392...242,844,609
Ensembl chr 2:242,792,661...242,843,487
JBrowse link
G Msh5 mutS homolog 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
JBrowse link
G Msh6 mutS homolog 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Rad51 RAD51 recombinase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad51b RAD51 paralog B enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
JBrowse link
G Rad51c RAD51 paralog C enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248
JBrowse link
G Rad51d RAD51 paralog D enables ISO (PMID:16717288) RGD PMID:16717288 NCBI chr10:67,805,720...67,824,452
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
calcium ion sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efcab9 EF-hand calcium binding domain 9 enables ISO
IBA
(MGI:6316499|PMID:31056283)
GO_REF:0000033
RGD
GO_Central
PMID:31056283 GO_REF:0000033 MGI:6316499 NCBI chr10:17,107,123...17,112,282
Ensembl chr10:17,107,123...17,112,289
JBrowse link
G Efhb EF hand domain family, member B enables ISO (PMID:30481768) RGD PMID:30481768 NCBI chr 9:6,372,191...6,441,678
Ensembl chr 9:6,372,194...6,441,919
JBrowse link
G Efhd1 EF-hand domain family, member D1 enables ISO
IBA
(PMID:26975899)
GO_REF:0000033
RGD
GO_Central
PMID:26975899 GO_REF:0000033 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
JBrowse link
G Micu1 mitochondrial calcium uptake 1 enables ISO
ISS
(PMID:27642082), (PMID:28615291), (PMID:32148862), (PMID:32494073), (PMID:32667285), (PMID:32762847), (PMID:32790952)
GO_REF:0000024
RGD
UniProt
PMID:27642082 PMID:28615291 PMID:32148862 PMID:32494073 PMID:32667285 More... GO_REF:0000024 NCBI chr20:27,668,681...27,816,322
Ensembl chr20:27,668,747...27,814,964
JBrowse link
G Micu2 mitochondrial calcium uptake 2 enables ISO
ISS
(PMID:28615291), (PMID:30699349), (PMID:31397067), (PMID:32148862), (PMID:32494073), (PMID:32667285), (PMID:32762847), (PMID:32790952)
GO_REF:0000024
RGD
UniProt
PMID:28615291 PMID:30699349 PMID:31397067 PMID:32148862 PMID:32494073 More... GO_REF:0000024 NCBI chr15:32,064,872...32,146,874
Ensembl chr15:32,064,875...32,147,094
JBrowse link
G Micu3 mitochondrial calcium uptake family, member 3 enables ISO
IDA
(PMID:29725115), (PMID:30699349)
PMID:31862210
RGD PMID:29725115 PMID:30699349 PMID:31862210 RGD:405650270 NCBI chr16:51,919,859...52,010,705
Ensembl chr16:51,925,225...52,010,613
JBrowse link
G Syt1 synaptotagmin 1 enables ISO (PMID:21521611) RGD PMID:21521611 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
DNA damage sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad23b RAD23 homolog B, nucleotide excision repair protein enables ISO (PMID:19941824) RGD PMID:19941824 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319
JBrowse link
G Sirt6 sirtuin 6 enables ISO (PMID:31995034), (PMID:32538779) RGD PMID:31995034 PMID:32538779 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor enables ISO (PMID:10873465), (PMID:19941824) RGD PMID:10873465 PMID:19941824 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
glucose sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gck glucokinase enables IDA PMID:17470517 BHF-UCL PMID:17470517 RGD:8554539 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gckr glucokinase regulator enables IDA
ISO
PMID:19807849
PMID:14627435
(PMID:14627435)
RGD PMID:14627435 PMID:19807849 PMID:14627435 RGD:8554135, RGD:1598592 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
osmolarity-sensing monoatomic cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn7a sodium voltage-gated channel alpha subunit 7 enables IDA
ISO
PMID:21084682
(MGI:3628881|PMID:11992118)
RGD PMID:11992118 PMID:21084682 MGI:3628881, RGD:401966867 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256
JBrowse link
G Tmem63a transmembrane protein 63a enables ISO (MGI:6378787|PMID:27045885) RGD PMID:27045885 MGI:6378787 NCBI chr13:92,662,872...92,696,186
Ensembl chr13:92,663,968...92,696,183
JBrowse link
G Tmem63b transmembrane protein 63B enables ISO (MGI:6378298|PMID:31243992), (MGI:6378787|PMID:27045885), (MGI:6514514|PMID:32375046) RGD PMID:27045885 PMID:31243992 PMID:32375046 MGI:6378298 MGI:6378787 MGI:6514514 NCBI chr 9:15,313,867...15,340,722
Ensembl chr 9:15,320,432...15,340,720
JBrowse link
G Tmem63c transmembrane protein 63c enables ISS
ISO
GO_REF:0000024
(MGI:6378787|PMID:27045885)
UniProt
RGD
PMID:27045885 GO_REF:0000024 MGI:6378787 NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:18279313 RGD:10047048 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
osmosensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 enables ISO MGI:2667379 (PMID:11025659), (PMID:12777254) RGD PMID:11025659 PMID:12777254 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
oxygen sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln2 egl-9 family hypoxia-inducible factor 2 enables ISO (PMID:11595184) RGD PMID:11595184 NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 enables ISO
IMP
(PMID:30922174)
(MGI:6208149|PMID:29887397), (MGI:6220487|PMID:26437605), (MGI:6442705|PMID:30922174)
RGD PMID:26437605 PMID:29887397 PMID:30922174 PMID:30922174 MGI:6208149 MGI:6220487 MGI:6442705, RGD:42722001 NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420
JBrowse link
G Park7 Parkinsonism associated deglycase enables ISO (MGI:3723371|PMID:17766438) RGD PMID:17766438 MGI:3723371 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
sterol sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc38a9 solute carrier family 38, member 9 enables ISS
ISO
GO_REF:0000024
(PMID:28336668)
UniProt
RGD
PMID:28336668 GO_REF:0000024 NCBI chr 2:44,291,637...44,374,897
Ensembl chr 2:44,291,989...44,368,955
JBrowse link
zinc ion sensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a4 solute carrier family 39 member 4 enables IEA
ISO
ISS
GO_REF:0000107
(PMID:32348750)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:32348750 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20731
    small molecule sensor activity 42
      DNA damage sensor activity + 18
      amino acid sensor activity + 2
      carbon monoxide sensor activity 0
      glucose sensor activity 2
      inositol pyrophosphate sensor activity 0
      lipid sensor activity + 1
      metal ion sensor activity + 8
      nitric oxide sensor activity 0
      osmosensor activity + 6
      oxygen sensor activity 3
      peroxide sensor activity 0
      phosphorelay sensor kinase activity 0
paths to the root