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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial [4Fe-4S] assembly complex
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Accession:GO:0120510 term browser browse the term
Definition:A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in mitochondria. In S. cerevisiae, it consists of Isa1 and Isa2. In humans it consists of ISCA1 and ISCA2. Additional proteins may be present.
Synonyms:exact_synonym: ISA complex
 related_synonym: iron-sulfur assembly complex



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mitochondrial [4Fe-4S] assembly complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Isca1 iron-sulfur cluster assembly 1 part_of ISO (PMID:25347204) RGD PMID:25347204 NCBI chr17:4,910,816...4,923,478
Ensembl chr17:4,905,287...4,917,955
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G Isca2 iron-sulfur cluster assembly 2 part_of ISO (PMID:25347204) RGD PMID:25347204 NCBI chr 6:104,418,509...104,420,019
Ensembl chr 6:104,418,454...104,420,045
Ensembl chr14:104,418,454...104,420,045
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Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21327
    protein-containing complex 6790
      iron-sulfur cluster assembly complex 17
        mitochondrial [4Fe-4S] assembly complex 2
Path 2
Term Annotations click to browse term
  cellular_component 21327
    cellular anatomical structure 21032
      organelle 14243
        intracellular organelle 13830
          intracellular membrane-bounded organelle 12255
            mitochondrion 1991
              mitochondrial protein-containing complex 180
                mitochondrial [4Fe-4S] assembly complex 2
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