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ONTOLOGY REPORT - ANNOTATIONS

Term:olefinic compound biosynthetic process
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Accession:GO:0120255 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms:exact_synonym: alkene substituted compound anabolic process;   alkene substituted compound anabolism;   alkene substituted compound biosynthesis;   alkene substituted compound biosynthetic process;   alkene substituted compound synthesis


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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IMP
IEA
ISO		 PMID:19342457
GO_REF:0000107
(PMID:19342457)		 Ensembl
RGD		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IMP
IBA		 PMID:19342457
GO_REF:0000033		 GO_Central PMID:19342457 GO_REF:0000033, RGD:4891166 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in IDA
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:19342457), (PMID:2256920)		 Ensembl
GO_Central
RGD		 PMID:2256920 PMID:19342457 PMID:11832364 GO_REF:0000033 GO_REF:0000107, RGD:727991 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:1741400), (PMID:19342457), (PMID:2256920), (PMID:23322723)
(PMID:1686470), (PMID:8645611)		 RGD PMID:1686470 PMID:1741400 PMID:2256920 PMID:8645611 PMID:19342457 More... NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
androst-4-ene-3,17-dione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inhba inhibin subunit beta A acts_upstream_of_or_within ISO (PMID:32954300) RGD PMID:32954300 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IMP
IEA
ISO		 PMID:19342457
GO_REF:0000107
(PMID:19342457)		 Ensembl
RGD		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IMP PMID:19342457 UniProt PMID:19342457 RGD:4891166 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in ISO (PMID:19342457), (PMID:2022736), (PMID:8506298) RGD PMID:2022736 PMID:8506298 PMID:19342457 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 NOT|involved_in ISO (PMID:9703385)
(PMID:19342457)		 RGD PMID:9703385 PMID:19342457 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19584291)		 Ensembl
RGD		 PMID:19584291 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP		 (PMID:19342457)
GO_REF:0000107		 RGD
Ensembl		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 (PMID:19584291)
GO_REF:0000107		 RGD
Ensembl		 PMID:19584291 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP		 (PMID:19342457)
GO_REF:0000107		 RGD
Ensembl		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (PMID:18818293) RGD PMID:18818293 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:12949260)
GO_REF:0000107		 RGD
Ensembl		 PMID:12949260 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) RGD PMID:16527843 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Dab2 DAB adaptor protein 2 IDA RGD PMID:17303656 RGD:7243836 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:16981135)
GO_REF:0000107		 RGD
Ensembl		 PMID:16981135 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:16981135)
GO_REF:0000107		 RGD
Ensembl		 PMID:16981135 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:20133449 RGD:10059648 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:1703300) RGD PMID:1703300 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 acts_upstream_of_or_within ISO MGI:3042568 (PMID:14963026) RGD PMID:14963026 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO
ISS		 (PMID:29403011)
GO_REF:0000024		 RGD
UniProt		 PMID:29403011 GO_REF:0000024 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO (PMID:18628520), (PMID:23132696)
(PMID:16356929)		 RGD PMID:16356929 PMID:18628520 PMID:23132696 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Egr1 early growth response 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8703054)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8703054 GO_REF:0000024 GO_REF:0000107 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:23045399 RGD:26884342 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir455 microRNA 455 IDA RGD PMID:23045399 RGD:26884342 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:19336506) RGD PMID:19336506 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:21333348)		 UniProt
RGD		 PMID:21333348 GO_REF:0000024 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 involved_in ISO (PMID:21333348) RGD PMID:21333348 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Gprc6a G protein-coupled receptor, class C, group 6, member A involved_in ISS
ISO		 GO_REF:0000024
(PMID:21333348)		 UniProt
RGD		 PMID:21333348 GO_REF:0000024 NCBI chr20:30,922,106...30,943,412
Ensembl chr20:30,922,106...30,943,412 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:22429315 RGD:7775068 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:16983398) RGD PMID:16983398 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:19883722 RGD:4145609 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2154536 (PMID:9618522)		 Ensembl
RGD		 PMID:9618522 GO_REF:0000107 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 involved_in IDA
ISO		 (PMID:9658408) RGD PMID:9658408 PMID:8612487 RGD:728619 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:16467141 RGD:4889544 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Inhba inhibin subunit beta A acts_upstream_of_or_within ISO (PMID:32274496) RGD PMID:32274496 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 involved_in ISO
ISS		 (PMID:10898110)
GO_REF:0000024		 RGD
UniProt		 PMID:10898110 GO_REF:0000024 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:19883722 RGD:4145609 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20535
    cellular process 19524
      metabolic process 12166
        olefinic compound metabolic process 183
          olefinic compound biosynthetic process 35
            (-)-secologanin biosynthetic process 0
            abscisic acid biosynthetic process + 0
            aldosterone biosynthetic process + 12
            andrastin A biosynthetic process 0
            androst-4-ene-3,17-dione biosynthetic process + 1
            chalcone biosynthetic process 0
            chanoclavine-I aldehyde biosynthetic process + 0
            cinnamic acid biosynthetic process 0
            cinnamic acid ester biosynthetic process + 0
            cortisol biosynthetic process + 11
            eugenol biosynthetic process 0
            ferulate biosynthetic process 0
            funalenone biosynthetic process 0
            geraniol biosynthetic process 0
            helvolic acid biosynthetic process + 0
            isopentenol biosynthetic process 0
            kojic acid biosynthetic process + 0
            neoxanthin biosynthetic process 0
            olefin biosynthetic process + 0
            paxilline biosynthetic process 0
            prenol biosynthetic process 0
            progesterone biosynthetic process + 9
            sinapate biosynthetic process 0
            stilbene biosynthetic process 0
            terrequinone A biosynthetic process + 0
            testosterone biosynthetic process + 15
            viridicatumtoxin biosynthetic process 0
            vomitoxin biosynthetic process 0
paths to the root