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ONTOLOGY REPORT - ANNOTATIONS

Term:apical plasma membrane urothelial plaque
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Accession:GO:0120001 term browser browse the term
Definition:A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.
Synonyms:exact_synonym: asymmetric unit membrane
 related_synonym: AUM


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apical plasma membrane urothelial plaque term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upk1a uroplakin 1A is_active_in ISO (PMID:22323295) RGD PMID:22323295 NCBI chr 1:85,859,672...85,870,147
Ensembl chr 1:85,859,671...85,870,354 		JBrowse link
G Upk1b uroplakin 1B located_in
is_active_in		 IEA
ISO		 GO_REF:0000107
(PMID:22323295)		 Ensembl
RGD		 PMID:22323295 GO_REF:0000107 NCBI chr11:61,953,687...61,991,029
Ensembl chr11:61,953,648...61,991,029 		JBrowse link
G Upk2 uroplakin 2 is_active_in ISO (PMID:22323295) RGD PMID:22323295 NCBI chr 8:44,779,198...44,781,190
Ensembl chr 8:44,779,198...44,781,190 		JBrowse link
G Upk3a uroplakin 3A is_active_in ISO (PMID:22323295), (PMID:26046524) RGD PMID:22323295 PMID:26046524 NCBI chr 7:116,128,981...116,139,950
Ensembl chr 7:116,134,874...116,139,948 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      cell periphery 6918
        plasma membrane 6433
          apical plasma membrane urothelial plaque 4
Path 2
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      cell periphery 6918
        plasma membrane 6433
          plasma membrane region 1474
            apical plasma membrane 445
              apical plasma membrane urothelial plaque 4
paths to the root