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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of sterol biosynthetic process
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Accession:GO:0106118 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.



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negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Chlsn cholesin involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:20,298,968...20,402,890
Ensembl chr12:15,185,707...15,289,069
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO
IEA
(PMID:24217618)
GO_REF:0000107
RGD
Ensembl
PMID:24217618 GO_REF:0000107 NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:71,720,486...71,736,999
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) RGD PMID:17202134 NCBI chr17:66,022,731...66,026,333
Ensembl chr17:61,331,669...61,334,285
JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) RGD PMID:26311497 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:133,329,655...133,329,753
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO
IEA
(PMID:17916878)
GO_REF:0000107
RGD
Ensembl
PMID:17916878 GO_REF:0000107 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:17916878)
Ensembl
RGD
PMID:17916878 GO_REF:0000107 NCBI chr 8:53,508,005...53,525,314
Ensembl chr 8:44,611,187...44,626,881
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19229075)
UniProt
RGD
PMID:19229075 GO_REF:0000024 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Gnai1 G protein subunit alpha i1 involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:38503280)
Ensembl
RGD
PMID:38503280 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 involved_in ISO
IEA
(PMID:11163209)
GO_REF:0000107
RGD
Ensembl
PMID:11163209 GO_REF:0000107 NCBI chr  X:41,225,956...41,290,030
Ensembl chr  X:37,410,811...37,464,430
JBrowse link
G Mir182 microRNA 182 involved_in ISO RNAcentral:URS000016FF9C_9606 (PMID:23823476) RGD PMID:23823476 NCBI chr 4:59,752,246...59,752,307
Ensembl chr 4:58,784,818...58,784,879
JBrowse link
G Mir96 microRNA 96 involved_in
acts_upstream_of
ISO RNAcentral:URS00001CC379_9606 (PMID:23823476)
(PMID:30460077)
RGD PMID:23823476 PMID:30460077 NCBI chr 4:59,755,841...59,755,946
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:32976883 RGD:405096663 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 involved_in ISO
IEA
(PMID:26311497)
GO_REF:0000107
RGD
Ensembl
PMID:26311497 GO_REF:0000107 NCBI chr14:12,766,539...12,796,461
Ensembl chr14:12,462,563...12,479,994
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in IEA
ISO
GO_REF:0000107
(PMID:38503280)
Ensembl
RGD
PMID:38503280 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) RGD PMID:33942715 NCBI chr 1:52,935,357...53,047,338
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Scap SREBF chaperone involved_in ISO
IEA
(PMID:32322062)
GO_REF:0000107
RGD
Ensembl
PMID:32322062 GO_REF:0000107 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISO
IEA
ISS
(PMID:12177166)
GO_REF:0000107
(PMID:8833906), (PMID:9062341)
MGI:2177958|MGI:2177959 (PMID:16046411), (PMID:9329978)
GO_REF:0000024
(PMID:32322062)
RGD
Ensembl
UniProt
PMID:8833906 PMID:9062341 PMID:9329978 PMID:12177166 PMID:16046411 More... GO_REF:0000024 GO_REF:0000107 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:33942715), (PMID:34021134)
(PMID:12177166), (PMID:38503280)
GO_REF:0000024
(PMID:32322062)
Ensembl
RGD
UniProt
PMID:12177166 PMID:32322062 PMID:33942715 PMID:34021134 PMID:38503280 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Yy2 YY2 transcription factor involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:41,253,481...41,257,103
Ensembl chr  X:37,410,811...37,464,430
JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:28,642,660...28,662,689
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within ISO
IEA
MGI:2183298 (PMID:16455790)
GO_REF:0000107
RGD
Ensembl
PMID:16455790 GO_REF:0000107 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Aqp8 aquaporin 8 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:30579780)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:30579780 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Cyp51 cytochrome P450, family 51 TAS RGD PMID:7665087 RGD:1298863 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IDA RGD PMID:10329655 RGD:632010 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO
IEA
(PMID:24217618)
GO_REF:0000107
RGD
Ensembl
PMID:24217618 GO_REF:0000107 NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:71,720,486...71,736,999
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Gpr146 G protein-coupled receptor 146 involved_in ISO
IEA
(PMID:38503280)
GO_REF:0000107
RGD
Ensembl
PMID:38503280 GO_REF:0000107 NCBI chr12:20,365,790...20,381,122
Ensembl chr12:15,251,813...15,267,206
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:29395055)
UniProt
RGD
PMID:29395055 GO_REF:0000024 NCBI chr 4:159,154,690...159,196,176
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Mvk mevalonate kinase NAS RGD PMID:2158094 RGD:728935 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO MGI:2180128 (PMID:14673138) RGD PMID:14673138 NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:96,045,958...96,073,404
JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
MGI:2148743|MGI:2180899 (PMID:16054043)
GO_Central
Ensembl
RGD
PMID:16054043 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:110,306,031...110,360,666
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      regulation of cellular process 13030
        regulation of metabolic process 6786
          regulation of biosynthetic process 5577
            regulation of lipid biosynthetic process 237
              regulation of steroid biosynthetic process 103
                regulation of sterol biosynthetic process 38
                  negative regulation of sterol biosynthetic process + 9
                  positive regulation of sterol biosynthetic process + 20
                  regulation of cholesterol biosynthetic process + 38
                  regulation of ergosterol biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        regulation of cellular process 13030
          regulation of metabolic process 6786
            regulation of primary metabolic process 5623
              regulation of lipid metabolic process 398
                regulation of lipid biosynthetic process 237
                  regulation of steroid biosynthetic process 103
                    regulation of sterol biosynthetic process 38
                      negative regulation of sterol biosynthetic process + 9
                      positive regulation of sterol biosynthetic process + 20
                      regulation of cholesterol biosynthetic process + 38
                      regulation of ergosterol biosynthetic process + 0
paths to the root