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ONTOLOGY REPORT - ANNOTATIONS

Term:modification of synaptic structure
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Accession:GO:0099563 term browser browse the term
Definition:Any process that modifies the structure/morphology of a synapse.
Comment:This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones.
Synonyms:exact_synonym: synapse remodelling
 only_in_taxon: NCBITaxon:33208 ! Metazoa


show annotations for term's descendants           Sort by:
modification of synaptic structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgrmc1 progesterone receptor membrane component 1 involved_in IGI PMID:25390368 ARUK-UCL PMID:25390368 RGD:12910997 NCBI chr  X:120,698,610...120,706,805 JBrowse link
G Rest RE1-silencing transcription factor involved_in IMP PMID:22960932 UniProt PMID:22960932 RGD:14397585 NCBI chr14:30,859,109...30,879,828 JBrowse link
modification of postsynaptic actin cytoskeleton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in IDA
IEP
IMP		 PMID:22485184 SynGO PMID:22485184 PMID:22485184 PMID:22485184 RGD:42721990, RGD:42721990, RGD:42721990 NCBI chr10:80,769,819...80,780,816 JBrowse link
G Cabp1 calcium binding protein 1 involved_in ISO (PMID:29478916) RGD PMID:29478916 NCBI chr12:41,385,234...41,448,930 JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 involved_in ISO
IEA		 (PMID:36264429)
GO_REF:0000107		 RGD
Ensembl		 PMID:36264429 GO_REF:0000107 NCBI chr 5:135,142,108...135,168,885 JBrowse link
G Cfl1 cofilin 1 involved_in IDA
EXP		 PMID:16025109 SynGO PMID:16025109 PMID:16025109 RGD:13702428, RGD:13702428 NCBI chr 1:212,227,124...212,230,656 JBrowse link
G Ctnna2 catenin alpha 2 involved_in ISO (PMID:15034585) RGD PMID:15034585 NCBI chr 4:109,294,249...110,443,409 JBrowse link
G Cttn cortactin involved_in IDA
IMP		 PMID:14684878 SynGO PMID:14684878 PMID:14684878 RGD:13702237, RGD:13702237 NCBI chr 1:199,599,710...199,635,254 JBrowse link
G Dixdc1 DIX domain containing 1 involved_in ISO
IEA		 (PMID:27829159)
GO_REF:0000107		 RGD
Ensembl		 PMID:27829159 GO_REF:0000107 NCBI chr 8:59,904,218...59,977,595 JBrowse link
G Itpka inositol-trisphosphate 3-kinase A involved_in IMP
IEP
IDA		 PMID:19890013 SynGO PMID:19890013 PMID:19890013 PMID:19890013 RGD:8553536, RGD:8553536, RGD:8553536 NCBI chr 3:127,179,841...127,188,405 JBrowse link
G Pfn1 profilin 1 involved_in ISO (PMID:26951674) RGD PMID:26951674 NCBI chr10:55,863,882...55,866,587 JBrowse link
G Pfn2 profilin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26951674)		 Ensembl
RGD		 PMID:26951674 GO_REF:0000107 NCBI chr 2:144,217,100...144,222,936 JBrowse link
G Sptb spectrin, beta, erythrocytic involved_in ISO (PMID:21297961) RGD PMID:21297961 NCBI chr 6:101,043,512...101,170,389 JBrowse link
G Wasf1 WASP family member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16862120)		 Ensembl
RGD		 PMID:16862120 GO_REF:0000107 NCBI chr20:45,908,458...45,956,118 JBrowse link
G Wasf3 WASP family member 3 involved_in ISO (PMID:16190876) RGD PMID:16190876 NCBI chr12:8,563,805...8,660,799 JBrowse link
modification of postsynaptic structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap44 Rho GTPase activating protein 44 involved_in ISO (PMID:23739967) RGD PMID:23739967 NCBI chr10:49,655,583...49,822,876 JBrowse link
G Cttn cortactin involved_in IMP
IDA		 PMID:14684878 SynGO PMID:14684878 PMID:14684878 RGD:13702237, RGD:13702237 NCBI chr 1:199,599,710...199,635,254 JBrowse link
G Dlgap3 DLG associated protein 3 involved_in ISO
IEA		 (PMID:17713528)
GO_REF:0000107		 RGD
Ensembl		 PMID:17713528 GO_REF:0000107 NCBI chr 5:139,491,972...139,562,625 JBrowse link
G Dlgap4 DLG associated protein 4 involved_in ISO
IEA		 (PMID:30664629)
GO_REF:0000107		 RGD
Ensembl		 PMID:30664629 GO_REF:0000107 NCBI chr 3:145,124,189...145,271,791 JBrowse link
G Drd1 dopamine receptor D1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25258080)		 Ensembl
RGD		 PMID:25258080 GO_REF:0000107 NCBI chr17:10,545,488...10,550,029 JBrowse link
G Filip1 filamin A interacting protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25220605)		 Ensembl
RGD		 PMID:25220605 GO_REF:0000107 NCBI chr 8:80,761,283...80,956,556 JBrowse link
G Rap1b RAP1B, member of RAS oncogene family involved_in ISO (PMID:26844834) RGD PMID:26844834 NCBI chr 7:53,423,039...53,456,349 JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IMP
IDA		 PMID:21555464 SynGO PMID:21555464 PMID:21555464 RGD:405650273, RGD:405650273 NCBI chr10:63,867,503...63,890,872 JBrowse link
G Stau1 staufen double-stranded RNA binding protein 1 involved_in IMP
IDA		 PMID:21635779 SynGO PMID:21635779 PMID:21635779 RGD:13792519, RGD:13792519 NCBI chr 3:155,680,000...155,725,969 JBrowse link
modification of synaptic structure, modulating synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp9 matrix metallopeptidase 9 involved_in IDA
EXP		 PMID:19047646 SynGO PMID:19047646 PMID:19047646 RGD:405650393, RGD:405650393 NCBI chr 3:174,103,474...174,111,434 JBrowse link
regulation of modification of postsynaptic actin cytoskeleton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amot angiomotin involved_in IDA
IMP		 PMID:29317530 SynGO PMID:29317530 PMID:29317530 RGD:405650325, RGD:405650325 NCBI chr  X:108,982,399...109,041,265 JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 involved_in IMP
IDA		 PMID:15673667 SynGO PMID:15673667 PMID:15673667 RGD:9684988, RGD:9684988 NCBI chr10:105,721,371...105,788,549 JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 involved_in IMP
IDA		 PMID:33094279 SynGO PMID:33094279 PMID:33094279 RGD:405650308, RGD:405650308 NCBI chr17:18,054,234...18,203,453 JBrowse link
G Cttnbp2 cortactin binding protein 2 involved_in IMP
IDA		 PMID:22262902 SynGO PMID:22262902 PMID:22262902 RGD:13702362, RGD:13702362 NCBI chr 4:46,800,975...46,964,681 JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:24050404) RGD PMID:24050404 NCBI chr 1:115,842,754...115,935,163 JBrowse link
G Dip2a disco-interacting protein 2 homolog A involved_in ISO (PMID:31600191) RGD PMID:31600191 NCBI chr20:12,284,037...12,373,519 JBrowse link
G Itsn1 intersectin 1 involved_in IDA
IMP		 PMID:19258322 SynGO PMID:19258322 PMID:19258322 RGD:13461864, RGD:13461864 NCBI chr11:44,464,515...44,646,598 JBrowse link
G Kalrn kalirin, RhoGEF kinase involved_in IDA
IMP		 PMID:18031682 SynGO PMID:18031682 PMID:18031682 RGD:12050112, RGD:12050112 NCBI chr11:79,703,345...80,309,210 JBrowse link
G Limk1 LIM domain kinase 1 involved_in IDA
IMP		 PMID:25884247 SynGO PMID:25884247 PMID:25884247 RGD:405650283, RGD:405650283 NCBI chr12:27,663,177...27,697,085 JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate involved_in IDA
IMP		 PMID:16202710 SynGO PMID:16202710 PMID:16202710 RGD:9685333, RGD:9685333 NCBI chr20:42,240,185...42,245,882 JBrowse link
G Myh10 myosin heavy chain 10 involved_in IDA
IMP		 PMID:20797537 SynGO PMID:20797537 PMID:20797537 RGD:12050124, RGD:12050124 NCBI chr10:53,393,901...53,525,174 JBrowse link
G Prmt8 protein arginine methyltransferase 8 involved_in ISO (PMID:32521269) RGD PMID:32521269 NCBI chr 4:160,535,813...160,618,193 JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISO (PMID:19553453) RGD PMID:19553453 NCBI chr 7:107,015,730...107,220,865 JBrowse link
G Rhoa ras homolog family member A involved_in ISO
IEA		 (PMID:21423166)
GO_REF:0000107		 RGD
Ensembl		 PMID:21423166 GO_REF:0000107 NCBI chr 8:117,870,548...117,904,303 JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 involved_in IMP
IDA		 PMID:15721239 SynGO PMID:15721239 PMID:15721239 RGD:12050147, RGD:12050147 NCBI chr11:42,517,527...42,866,280 JBrowse link
regulation of modification of postsynaptic structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 involved_in IMP
IDA		 PMID:27713690 SynGO PMID:27713690 PMID:27713690 RGD:405650302, RGD:405650302 NCBI chr 9:90,039,720...90,475,196 JBrowse link
G Ank3 ankyrin 3 involved_in IMP
IDA		 PMID:25374361 SynGO PMID:25374361 PMID:25374361 RGD:405650220, RGD:405650220 NCBI chr20:18,602,267...19,225,831 JBrowse link
G Camkv CaM kinase-like vesicle-associated involved_in IEA
ISO		 GO_REF:0000107
(PMID:27796283)		 Ensembl
RGD		 PMID:27796283 GO_REF:0000107 NCBI chr 8:117,505,439...117,519,785 JBrowse link
G Cd44 CD44 molecule involved_in EXP
IDA
IMP		 PMID:27798233 SynGO PMID:27798233 PMID:27798233 PMID:27798233 RGD:405650378, RGD:405650378, RGD:405650378 NCBI chr 3:109,610,824...109,699,776 JBrowse link
G Cdc42 cell division cycle 42 involved_in IMP
IDA		 PMID:21423166 SynGO PMID:21423166 PMID:21423166 RGD:5688281, RGD:5688281 NCBI chr 5:154,838,478...154,876,629 JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in IMP
IDA		 PMID:25698751 SynGO PMID:25698751 PMID:25698751 RGD:13702150, RGD:13702150 NCBI chr11:3,337,478...3,364,015 JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26972007)		 Ensembl
RGD		 PMID:26972007 GO_REF:0000107 NCBI chr19:52,867,900...52,907,308 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IMP
IDA		 PMID:23864697 SynGO PMID:23864697 PMID:23864697 RGD:13702314, RGD:13702314 NCBI chr11:76,004,502...76,154,665 JBrowse link
G Mrtfa myocardin related transcription factor A involved_in IMP
IDA		 PMID:29335431 SynGO PMID:29335431 PMID:29335431 RGD:405650348, RGD:405650348 NCBI chr 7:112,544,305...112,714,418 JBrowse link
G Mrtfb myocardin related transcription factor B involved_in IMP
IDA		 PMID:29335431 SynGO PMID:29335431 PMID:29335431 RGD:405650348, RGD:405650348 NCBI chr10:1,116,315...1,278,106 JBrowse link
G Myo5b myosin Vb involved_in IDA
IMP		 PMID:18984164 SynGO PMID:18984164 PMID:18984164 RGD:11533643, RGD:11533643 NCBI chr18:70,313,717...70,613,918 JBrowse link
G Nf1 neurofibromin 1 involved_in IDA
EXP
IMP		 PMID:24431436 SynGO PMID:24431436 PMID:24431436 PMID:24431436 RGD:155230796, RGD:155230796, RGD:155230796 NCBI chr10:64,803,986...65,037,086 JBrowse link
G Pdxp pyridoxal phosphatase involved_in ISO
IEA		 (PMID:27212638)
GO_REF:0000107		 RGD
Ensembl		 PMID:27212638 GO_REF:0000107 NCBI chr 7:110,472,515...110,477,963 JBrowse link
G Phactr1 phosphatase and actin regulator 1 involved_in IMP
IDA		 PMID:32975518 SynGO PMID:32975518 PMID:32975518 RGD:405650326, RGD:405650326 NCBI chr17:21,560,364...22,040,166 JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:26490870) RGD PMID:26490870 NCBI chr 2:164,207,513...164,322,157 JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:21423166) RGD PMID:21423166 NCBI chr 8:117,870,548...117,904,303 JBrowse link
G Rhob ras homolog family member B involved_in ISO (PMID:20203211) RGD PMID:20203211 NCBI chr 6:31,363,752...31,365,926 JBrowse link
G Strn striatin involved_in IMP
IDA		 PMID:29802198 SynGO PMID:29802198 PMID:29802198 RGD:405650211, RGD:405650211 NCBI chr 6:22,087,419...22,174,284 JBrowse link
G Strn4 striatin 4 involved_in IDA
IMP		 PMID:28442576 SynGO PMID:28442576 PMID:28442576 RGD:405650263, RGD:405650263 NCBI chr 1:77,482,267...77,511,862 JBrowse link
regulation of modification of synapse structure, modulating synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif5b kinesin family member 5B involved_in ISO
IEA		 (PMID:31961321)
GO_REF:0000107		 RGD
Ensembl		 PMID:31961321 GO_REF:0000107 NCBI chr17:56,185,386...56,222,990 JBrowse link
G Zdhhc17 zinc finger DHHC-type palmitoyltransferase 17 involved_in ISO
IEA		 (PMID:24277827)
GO_REF:0000107		 RGD
Ensembl		 PMID:24277827 GO_REF:0000107 NCBI chr 7:48,256,269...48,320,000 JBrowse link
regulation of modification of synaptic structure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IGI
ISO		 PMID:24658113
ComplexPortal:CPX-1134|UniProtKB:Q03137 (PMID:24658113)		 RGD PMID:24658113 PMID:24658113 RGD:12911004 NCBI chr 3:35,377,587...35,480,843 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:29780879) RGD PMID:29780879 NCBI chr 1:181,156,071...181,169,458 JBrowse link
G Epha4 Eph receptor A4 involved_in IGI
ISO		 PMID:24658113
ComplexPortal:CPX-1134|UniProtKB:P00520 (PMID:24658113)		 RGD PMID:24658113 PMID:24658113 RGD:12911004 NCBI chr 9:86,263,982...86,406,744 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      cellular component organization or biogenesis 7187
        cellular component organization 6903
          cell junction organization 986
            synapse organization 706
              modification of synaptic structure 62
                modification of postsynaptic structure + 54
                modification of synaptic structure, modulating synaptic transmission 1
                regulation of modification of synaptic structure + 38
paths to the root