trans-synaptic signaling - Ontology Report

GO_REF:0000107

NCBI chr19:494,172...499,003
Ensembl chr19:606,120...611,501

immunoglobulin superfamily member 11

involved_in

IEA

GO_REF:0000107

NCBI chr 3:116,033,187...116,153,134
Ensembl chr 3:122,948,246...122,972,742

neurexin 3

involved_in

ISO

(PMID:26030848)

PMID:26030848

NCBI chr14:58,729,335...60,444,769
Ensembl chr14:78,002,036...79,619,696

PTPRD

protein tyrosine phosphatase receptor type D

involved_in

IEA

GO_REF:0000107

NCBI chr 9:8,113,171...10,420,732
Ensembl chr 9:8,288,569...8,831,227

PTPRS

protein tyrosine phosphatase receptor type S

involved_in

IEA

GO_REF:0000107

NCBI chr19:4,227,038...4,361,958
Ensembl chr19:5,168,599...5,247,778

calcium ion-regulated exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

ISO

(PMID:10670432)

PMID:10670432

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

DOC2B

double C2 domain beta

involved_in

ISO

PMID:20150444
(PMID:20150444)

PMID:20150444

RGD:8554647

NCBI chr17:19,854...58,336

regulating synaptic membrane exocytosis 1

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:17124501)

PMID:17124501

GO_REF:0000118

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:17124501)

PMID:17124501

GO_REF:0000118

NCBI chr 8:100,156,403...100,894,128

regulating synaptic membrane exocytosis 3

involved_in

IEA

GO_REF:0000118

NCBI chr 1:39,886,961...39,958,519
Ensembl chr 1:41,239,798...41,278,282

regulating synaptic membrane exocytosis 4

involved_in

IEA

GO_REF:0000118

NCBI chr20:41,082,200...41,141,119
Ensembl chr20:42,180,764...42,234,847

synaptosome associated protein 25

ISO

PMID:14980208

RGD:1581082

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

synaptotagmin 1

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

SYT11

synaptotagmin 11

involved_in

IEA

GO_REF:0000118

NCBI chr 1:131,193,999...131,218,752
Ensembl chr 1:135,026,032...135,046,943

synaptotagmin 12

involved_in

IEA

GO_REF:0000118

NCBI chr11:62,383,485...62,412,451
Ensembl chr11:65,709,808...65,733,010

SYT13

synaptotagmin 13

involved_in

IEA

GO_REF:0000118

NCBI chr11:45,197,691...45,243,814
Ensembl chr11:45,690,894...45,736,503

SYT2

synaptotagmin 2

involved_in

IEA

GO_REF:0000118

NCBI chr 1:178,187,872...178,308,522
Ensembl chr 1:182,490,401...182,538,123

synaptotagmin 4

involved_in

IEA

GO_REF:0000118

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

SYT5

synaptotagmin 5

involved_in

IEA

GO_REF:0000118

NCBI chr19:52,214,261...52,221,678
Ensembl chr19:60,909,026...60,916,436

SYT7

synaptotagmin 7

involved_in

IEA

GO_REF:0000118

NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375

SYT8

synaptotagmin 8

involved_in

IEA

GO_REF:0000118

NCBI chr11:1,867,572...1,874,115
Ensembl chr11:1,902,554...1,910,084

calcium-dependent activation of synaptic vesicle fusion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

double C2 domain alpha

involved_in

IEA

GO_REF:0000107

Ensembl chr16:30,378,922...30,384,142

DOC2B

double C2 domain beta

involved_in

ISO

PMID:22036572
(PMID:20150444)

PMID:20150444 PMID:22036572

RGD:155230732

NCBI chr17:19,854...58,336

synaptotagmin 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

SYT2

synaptotagmin 2

involved_in

ISO

(PMID:17192432)

PMID:17192432

NCBI chr 1:178,187,872...178,308,522
Ensembl chr 1:182,490,401...182,538,123

SYT7

synaptotagmin 7

involved_in

ISO

(PMID:24267651)

PMID:24267651

NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375

SYT9

synaptotagmin 9

involved_in

IEA

GO_REF:0000107

NCBI chr11:7,350,612...7,565,272
Ensembl chr11:7,032,803...7,247,187

chemical synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACP1

acid phosphatase 1

ISO

PMID:10480315

RGD:631746

NCBI chr2A:257,892...271,320
Ensembl chr2A:253,656...267,086

AGRN

agrin

acts_upstream_of_or_within

ISO

(PMID:8653788)

PMID:8653788 PMID:15883200

RGD:1578368

Ensembl chr 1:936,000...966,808

APBA1

amyloid beta precursor protein binding family A member 1

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 9:55,124,040...55,365,521
Ensembl chr 9:68,191,877...68,275,554

APBA2

amyloid beta precursor protein binding family A member 2

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:17167098)

PMID:17167098

GO_REF:0000118

NCBI chr15:167,863...400,296
Ensembl chr15:27,174,217...27,241,529

APBA3

amyloid beta precursor protein binding family A member 3

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr19:2,774,535...2,785,404
Ensembl chr19:3,722,896...3,734,153

amyloid beta precursor protein

NOT|involved_in

ISO

(PMID:18216187)

PMID:18216187

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

PMID:10611370 PMID:12040045 PMID:14673106 PMID:15548652

calcium voltage-gated channel subunit alpha1 A

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:12040045)
(PMID:10611370), (PMID:15548652)

RGD
TreeGrafter
MGI

GO_REF:0000118 RGD:1358385

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

CACNA1C

calcium voltage-gated channel subunit alpha1 C

acts_upstream_of_or_within

ISO

(PMID:16251435)

PMID:16251435

NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826

CACNA1E

calcium voltage-gated channel subunit alpha1 E

involved_in

IEA

GO_REF:0000118

NCBI chr 1:156,796,855...157,296,987
Ensembl chr 1:160,628,089...160,949,270

CACNA1G

calcium voltage-gated channel subunit alpha1 G

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166

CACNB2

calcium voltage-gated channel auxiliary subunit beta 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr10:18,459,528...18,862,495
Ensembl chr10:18,795,832...19,195,226

CARTPT

CART prepropeptide

involved_in

IEA

GO_REF:0000043

NCBI chr 5:43,591,683...43,593,586
Ensembl chr 5:44,236,114...44,238,229

CAV2

caveolin 2

ISO

PMID:11883949

RGD:632372

NCBI chr 7:108,254,074...108,480,716
Ensembl chr 7:121,168,579...121,177,415

CDH8

cadherin 8

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr16:41,935,706...42,326,055
Ensembl chr16:61,054,214...61,437,569

CEP89

centrosomal protein 89

involved_in

IEA

GO_REF:0000002

NCBI chr19:29,790,653...29,895,083
Ensembl chr19:38,547,861...38,638,785

CHAT

choline O-acetyltransferase

acts_upstream_of_or_within

ISO

(PMID:12533614)

PMID:12533614

NCBI chr10:44,574,925...44,629,618

CHRM1

cholinergic receptor muscarinic 1

involved_in

IEA

GO_REF:0000118

NCBI chr11:58,261,476...58,274,685
Ensembl chr11:61,614,818...61,616,200

CHRM2

cholinergic receptor muscarinic 2

involved_in

IEA

GO_REF:0000118

NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796

CHRM4

cholinergic receptor muscarinic 4

involved_in

IEA

GO_REF:0000118

NCBI chr11:46,342,384...46,350,366
Ensembl chr11:46,894,615...46,896,054

CHRM5

cholinergic receptor muscarinic 5

involved_in

IEA

GO_REF:0000118

NCBI chr15:12,478,656...12,575,512
Ensembl chr15:31,406,198...31,407,796

contactin associated protein 2

involved_in

ISO

(PMID:23074245)

PMID:23074245

NCBI chr 7:137,858,607...140,150,820
Ensembl chr 7:150,345,240...152,626,818

CTNNB1

catenin beta 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030

DLG1

discs large MAGUK scaffold protein 1

involved_in

IEA

GO_REF:0000002 GO_REF:0000118

NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987

DLG2

discs large MAGUK scaffold protein 2

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:12890763)

InterPro
TreeGrafter
MGI

PMID:12890763

GO_REF:0000002 GO_REF:0000118

NCBI chr11:78,517,601...80,684,319
Ensembl chr11:82,128,746...84,263,241

DLG3

discs large MAGUK scaffold protein 3

involved_in

IEA

GO_REF:0000002 GO_REF:0000118

NCBI chr X:59,712,755...59,773,372
Ensembl chr X:69,771,477...69,831,369

discs large MAGUK scaffold protein 4

involved_in

IEA

GO_REF:0000002 GO_REF:0000118

NCBI chr17:7,219,911...7,247,509
Ensembl chr17:7,207,483...7,235,985

DMXL2

Dmx like 2

acts_upstream_of_or_within

ISO

(PMID:30735494)

PMID:30735494

NCBI chr15:30,386,009...30,557,976
Ensembl chr15:48,719,150...48,890,708

double C2 domain alpha

involved_in

IEA

GO_REF:0000117

Ensembl chr16:30,378,922...30,384,142

ELFN1

extracellular leucine rich repeat and fibronectin type III domain containing 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:1,920,075...2,002,910
Ensembl chr 7:2,116,452...2,118,938

ELFN2

extracellular leucine rich repeat and fibronectin type III domain containing 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr22:18,254,614...18,343,027
Ensembl chr22:36,120,755...36,123,217

EXOC4

exocyst complex component 4

involved_in

ISO
IEA

PMID:16601687

GO_REF:0000118 RGD:2314411

NCBI chr 7:125,226,107...126,030,486
Ensembl chr 7:137,734,400...138,536,214

EXT1

exostosin glycosyltransferase 1

acts_upstream_of_or_within

ISO

(PMID:22411800)

PMID:22411800

NCBI chr 8:114,489,325...114,803,763
Ensembl chr 8:117,011,919...117,324,851

FBXO41

F-box protein 41

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2A:73,307,478...73,337,242
Ensembl chr2A:74,800,490...74,811,075

FGF12

fibroblast growth factor 12

acts_upstream_of_or_within

ISO

(PMID:17678857)

PMID:17678857

NCBI chr 3:189,430,811...190,017,254
Ensembl chr 3:199,778,545...200,358,744

FGF14

fibroblast growth factor 14

acts_upstream_of_or_within

ISO

(PMID:17678857)

PMID:17678857

NCBI chr13:82,869,491...83,563,099
Ensembl chr13:102,016,568...102,696,330

GABRA3

gamma-aminobutyric acid type A receptor subunit alpha3

ISO

PMID:12433958

RGD:1298923

NCBI chr X:141,739,962...142,001,041
Ensembl chr X:151,697,537...151,878,484

GABRA5

gamma-aminobutyric acid type A receptor subunit alpha5

ISO

PMID:2153588 PMID:15246695

RGD:1358392 RGD:61593

NCBI chr15:2,953,857...3,036,722
Ensembl chr15:24,300,300...24,382,730

GABRD

gamma-aminobutyric acid type A receptor subunit delta

ISO

PMID:12356876

RGD:727440

NCBI chr 1:731,714...743,165
Ensembl chr 1:1,883,955...1,895,102

GABRG1

gamma-aminobutyric acid type A receptor subunit gamma1

acts_upstream_of_or_within

ISO

(PMID:11891290)

PMID:11891290

NCBI chr 4:76,034,539...76,121,797
Ensembl chr 4:86,762,417...86,850,033

GABRG2

gamma-aminobutyric acid type A receptor subunit gamma2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:157,436,113...157,529,586
Ensembl chr 5:164,068,122...164,222,179

GIPC1

GIPC PDZ domain containing family member 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701

GJC1

gap junction protein gamma 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:12,492,285...12,524,615
Ensembl chr17:12,689,251...12,690,441

GJD2

gap junction protein delta 2

acts_upstream_of_or_within

ISO

(PMID:15659592)

PMID:15659592

NCBI chr15:13,668,639...13,672,691
Ensembl chr15:31,928,157...31,931,474

glycine receptor alpha 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567

GLRB

glycine receptor beta

involved_in

IEA

GO_REF:0000107

NCBI chr 4:149,422,654...149,518,669
Ensembl chr 4:161,236,610...161,333,035

GLS

glutaminase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:78,182,117...78,267,071
Ensembl chr2B:196,098,910...196,183,323

glutamate ionotropic receptor AMPA type subunit 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660

glutamate ionotropic receptor AMPA type subunit 2

acts_upstream_of_or_within

ISO

(PMID:14687553)

PMID:12554656 PMID:14687553

RGD:728773

NCBI chr 4:149,566,563...149,712,135
Ensembl chr 4:161,380,933...161,524,376

GRIA4

glutamate ionotropic receptor AMPA type subunit 4

ISO

PMID:2166337

RGD:728438

NCBI chr11:100,498,632...100,873,764
Ensembl chr11:103,983,862...104,355,280

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within

ISO
IEA

PMID:1648177

GO_REF:0000107 RGD:69852

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

glutamate ionotropic receptor kainate type subunit 5

ISO

PMID:12080343

RGD:625595

NCBI chr19:38,886,108...38,956,938
Ensembl chr19:47,389,804...47,544,604

glutamate ionotropic receptor NMDA type subunit 2A

acts_upstream_of_or_within

ISO
IEA

PMID:15306812

GO_REF:0000107 RGD:1358643

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

glutamate ionotropic receptor NMDA type subunit 2B

acts_upstream_of_or_within

ISO

(PMID:8789948)

PMID:8789948

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

GRM1

glutamate metabotropic receptor 1

ISO

PMID:12514201

RGD:728822

NCBI chr 6:143,819,364...144,231,304
Ensembl chr 6:148,537,036...148,947,047

GRM4

glutamate metabotropic receptor 4

acts_upstream_of_or_within

ISO

(PMID:8815915)

PMID:8815915

NCBI chr 6:33,592,030...33,718,712
Ensembl chr 6:34,696,058...34,830,868

glutamate metabotropic receptor 5

ISO

PMID:12514208

RGD:728711

NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953

GRM6

glutamate metabotropic receptor 6

ISO

PMID:8389366

RGD:69945

NCBI chr 5:174,142,754...174,156,294
Ensembl chr 5:181,434,031...181,447,341

GRM7

glutamate metabotropic receptor 7

involved_in

IEA

GO_REF:0000107

NCBI chr 3:6,811,005...7,691,344
Ensembl chr 3:6,907,180...7,933,536

glutamate metabotropic receptor 8

involved_in

ISO

PMID:15275822

PMID:15275822

RGD:6484726

NCBI chr 7:118,430,086...119,249,147

HNMT

histamine N-methyltransferase

acts_upstream_of_or_within

ISO

(PMID:29162912)

PMID:29162912

NCBI chr2B:21,840,342...21,892,744
Ensembl chr2B:142,036,321...142,088,315

HRH1

histamine receptor H1

involved_in

ISO
IEA

PMID:12419527

GO_REF:0000118 RGD:727463

NCBI chr 3:11,074,451...11,199,871
Ensembl chr 3:11,541,294...11,542,757

HRH2

histamine receptor H2

involved_in

IEA

GO_REF:0000118

NCBI chr 5:171,004,893...171,057,539
Ensembl chr 5:177,928,039...177,931,566

HRH3

histamine receptor H3

involved_in

IEA

GO_REF:0000118

NCBI chr20:58,581,228...58,586,585
Ensembl chr20:59,901,327...59,909,901

HRH4

histamine receptor H4

involved_in

IEA

GO_REF:0000118

NCBI chr18:17,711,852...17,731,500
Ensembl chr18:21,332,651...21,351,930

5-hydroxytryptamine receptor 1B

involved_in

ISO
IEA

RGD
UniProt
InterPro

PMID:15328035

GO_REF:0000002 GO_REF:0000104 RGD:1358659

NCBI chr 6:75,309,078...75,313,747
Ensembl chr 6:78,596,408...78,597,580

HTR1D

5-hydroxytryptamine receptor 1D

involved_in

IEA

GO_REF:0000002

NCBI chr 1:22,378,262...22,403,918
Ensembl chr 1:23,371,492...23,372,625

HTR2A

5-hydroxytryptamine receptor 2A

involved_in

IEA

GO_REF:0000118

NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826

HTR2B

5-hydroxytryptamine receptor 2B

involved_in

IEA

GO_REF:0000118

NCBI chr2B:118,362,719...118,381,253
Ensembl chr2B:237,153,709...237,170,591

HTR2C

5-hydroxytryptamine receptor 2C

involved_in

IEA

GO_REF:0000118

NCBI chr X:103,673,172...103,999,133
Ensembl chr X:114,199,485...114,503,201

HTR4

5-hydroxytryptamine receptor 4

involved_in

IEA

GO_REF:0000002

NCBI chr 5:143,918,925...144,208,779
Ensembl chr 5:149,889,969...150,108,357

HTR6

5-hydroxytryptamine receptor 6

involved_in

IEA

GO_REF:0000118

NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680

HTR7

5-hydroxytryptamine receptor 7

involved_in

IEA

GO_REF:0000002

NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158

KCNMA1

potassium calcium-activated channel subfamily M alpha 1

acts_upstream_of_or_within

ISO

(PMID:15194823)

PMID:15194823

NCBI chr10:73,391,297...74,158,488
Ensembl chr10:76,062,047...76,820,644

LARGE xylosyl- and glucuronyltransferase 1

acts_upstream_of_or_within

ISO

(PMID:23222475)
(PMID:16111892)

PMID:16111892 PMID:23222475

NCBI chr22:14,077,463...14,929,250

neuronal acetylcholine receptor subunit alpha-7

involved_in

ISO

(PMID:8145738)

PMID:8145738

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

LOC100983617

protocadherin-8

ISO

PMID:10383464

RGD:68758

NCBI chr13:33,880,543...33,886,243
Ensembl chr13:52,688,522...52,692,399

LRP6

LDL receptor related protein 6

ISO

PMID:20404321

RGD:4110125

NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973

LRP8

LDL receptor related protein 8

involved_in

IEA

GO_REF:0000107

NCBI chr 1:52,515,534...52,600,390
Ensembl chr 1:54,114,909...54,199,452

methyl-CpG binding protein 2

acts_upstream_of_or_within

ISO

(PMID:16399702)

PMID:16399702

NCBI chr X:143,571,864...143,647,192
Ensembl chr X:153,465,204...153,527,854

MET

MET proto-oncogene, receptor tyrosine kinase

involved_in

ISO

(PMID:21490227)

PMID:21490227

NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159

MINK1

misshapen like kinase 1

involved_in

ISO

PMID:21048137

PMID:21048137

RGD:8553980

NCBI chr17:4,879,851...4,944,374
Ensembl chr17:4,868,620...4,932,789

MYCBPAP

MYCBP associated protein

involved_in

ISO

PMID:15607946

PMID:15607946

RGD:1359747

NCBI chr17:44,602,693...44,625,330
Ensembl chr17:49,476,361...49,499,101

MYO5A

myosin VA

acts_upstream_of_or_within

ISO

(PMID:15316067)

PMID:15316067

NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319

MYO6

myosin VI

acts_upstream_of_or_within

ISO

(PMID:16819522)

NCBI chr 6:73,593,794...73,764,352
Ensembl chr 6:76,951,634...77,048,796

NPR2

natriuretic peptide receptor 2

involved_in

IEA

GO_REF:0000107

NCBI chr 9:35,642,534...35,660,210
Ensembl chr 9:36,445,576...36,462,637

NPY

neuropeptide Y

ISO

PMID:12482942

RGD:628512

NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657

NPY5R

neuropeptide Y receptor Y5

acts_upstream_of_or_within

ISO

(PMID:10557353)

PMID:10557353

NCBI chr 4:155,603,739...155,612,302

neurexin 1

acts_upstream_of_or_within

ISO

(PMID:12827191)

NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277

neurexin 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:59,959,917...60,078,093
Ensembl chr11:63,303,659...63,409,687

neurexin 3

acts_upstream_of_or_within

ISO

(PMID:12827191)

NCBI chr14:58,729,335...60,444,769
Ensembl chr14:78,002,036...79,619,696

purinergic receptor P2X 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:129,969,793...129,974,399

purinergic receptor P2X 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:52,579,190...52,614,329
Ensembl chr 3:160,070,875...160,106,120

PAFAH1B1

platelet activating factor acetylhydrolase 1b regulatory subunit 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:2,584,349...2,676,928
Ensembl chr17:2,590,007...2,680,994

PDYN

prodynorphin

involved_in

IEA

UniProt
TreeGrafter

GO_REF:0000043 GO_REF:0000118

NCBI chr20:2,092,171...2,108,141
Ensembl chr20:1,856,850...1,872,452

PENK

proenkephalin

involved_in

IEA

GO_REF:0000118

NCBI chr 8:52,864,388...52,870,144
Ensembl chr 8:50,234,170...50,239,949

PMCH

pro-melanin concentrating hormone

involved_in

IEA

GO_REF:0000002

NCBI chr12:99,783,925...99,785,292
Ensembl chr12:103,181,497...103,182,616

PNOC

prepronociceptin

involved_in

ISO
IEA

RGD
TreeGrafter
InterPro

PMID:11826101

GO_REF:0000002 GO_REF:0000118 RGD:633635

NCBI chr 8:27,596,413...27,622,844
Ensembl chr 8:24,796,638...24,822,758

protein kinase C gamma

involved_in

IEA

GO_REF:0000107

NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977

PTCHD1

patched domain containing 1

involved_in

IEA

GO_REF:0000118

NCBI chr X:15,929,619...15,991,194
Ensembl chr X:23,305,555...23,366,273

RAPSN

receptor associated protein of the synapse

involved_in

IEA

GO_REF:0000002

NCBI chr11:47,387,324...47,398,579
Ensembl chr11:47,940,530...47,951,667

RGS19

regulator of G protein signaling 19

acts_upstream_of_or_within

ISO

(PMID:16819522)

Ensembl chr20:61,987,428...61,993,936

SLC12A4

solute carrier family 12 member 4

involved_in

IEA

GO_REF:0000118

NCBI chr16:48,285,265...48,309,614
Ensembl chr16:67,673,087...67,697,280

SLC12A5

solute carrier family 12 member 5

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr20:42,359,005...42,397,412
Ensembl chr20:43,445,182...43,483,132

SLC12A6

solute carrier family 12 member 6

involved_in

IEA

GO_REF:0000118

NCBI chr15:12,741,526...12,846,894
Ensembl chr15:31,576,756...31,680,061

SLC12A7

solute carrier family 12 member 7

involved_in

IEA

GO_REF:0000118

Ensembl chr 5:1,094,769...1,147,759

SLC17A7

solute carrier family 17 member 7

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:46,443,076...46,455,195
Ensembl chr19:55,365,811...55,377,438

SLC18A3

solute carrier family 18 member A3

involved_in

IEA

GO_REF:0000118

NCBI chr10:44,630,006...44,632,419

SLITRK5

SLIT and NTRK like family member 5

acts_upstream_of_or_within

ISO

(PMID:20418887)

PMID:20418887

NCBI chr13:68,810,639...68,831,189
Ensembl chr13:87,980,905...87,983,781

SNAP91

synaptosome associated protein 91

involved_in

ISO

(PMID:11102472)

PMID:11102472

NCBI chr 6:81,441,792...81,600,505
Ensembl chr 6:84,720,850...84,874,407

SNAP associated protein

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095

synuclein alpha

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

SNCB

synuclein beta

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 5:171,918,297...171,928,672
Ensembl chr 5:178,988,439...178,998,800

SNCG

synuclein gamma

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:20974939)

PMID:20974939

GO_REF:0000118

NCBI chr10:83,383,566...83,391,064

SPG11

SPG11 vesicle trafficking associated, spatacsin

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616

SV2A

synaptic vesicle glycoprotein 2A

involved_in

IEA

GO_REF:0000002

NCBI chr 1:125,247,429...125,262,041
Ensembl chr 1:128,904,151...128,918,829

SV2B

synaptic vesicle glycoprotein 2B

involved_in

IEA

GO_REF:0000002

NCBI chr15:69,793,642...69,989,339
Ensembl chr15:89,114,744...89,184,370

SV2C

synaptic vesicle glycoprotein 2C

involved_in

IEA

GO_REF:0000002

NCBI chr 5:38,969,056...39,222,300
Ensembl chr 5:39,566,207...39,836,852

SYT10

synaptotagmin 10

involved_in

ISO

(PMID:21496647)

PMID:21496647

NCBI chr12:52,761,294...52,830,221
Ensembl chr12:55,364,714...55,429,298

TAC1

tachykinin precursor 1

involved_in

IEA

GO_REF:0000043

NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389

TPGS1

tubulin polyglutamylase complex subunit 1

acts_upstream_of_or_within

ISO

(PMID:17360631)

PMID:17360631

NCBI chr19:614,279...625,715

unc-13 homolog A

involved_in

IEA

GO_REF:0000002

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

unc-13 homolog B

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:12070347)

InterPro
MGI

PMID:12070347

GO_REF:0000002

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

unc-13 homolog C

acts_upstream_of_or_within

ISO

(PMID:11150314)

PMID:11150314

NCBI chr15:32,914,784...33,563,610

USP14

ubiquitin specific peptidase 14

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr18:14,104,754...14,158,402
Ensembl chr18:17,745,733...17,797,070

VDAC1

voltage dependent anion channel 1

acts_upstream_of_or_within

ISO

(PMID:11907043)

NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005

VDAC3

voltage dependent anion channel 3

acts_upstream_of_or_within

ISO

(PMID:11907043)

NCBI chr 8:41,638,522...41,652,637
Ensembl chr 8:39,082,698...39,097,437

chemical synaptic transmission, postsynaptic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

involved_in

ISO

(PMID:26085624)

PMID:26085624

NCBI chr12:96,313,293...97,559,597
Ensembl chr12:99,737,252...100,968,475

EEA1

early endosome antigen 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:90,299,582...90,457,109
Ensembl chr12:93,611,628...93,767,583

INSYN1

inhibitory synaptic factor 1

involved_in

IEA

GO_REF:0000107

NCBI chr15:52,650,196...52,663,270
Ensembl chr15:71,405,502...71,418,269

INSYN2A

inhibitory synaptic factor 2A

involved_in

ISO

(PMID:27609886)

PMID:27609886

NCBI chr10:123,716,226...123,777,268
Ensembl chr10:127,972,818...128,033,414

KCNK2

potassium two pore domain channel subfamily K member 2

involved_in

IEA

GO_REF:0000107

NCBI chr 1:190,576,180...190,807,367
Ensembl chr 1:195,430,994...195,662,840

NOTCH1

notch receptor 1

involved_in

IEA

GO_REF:0000107

NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740

dopamine uptake involved in synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

dopamine receptor D2

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

PARK7

Parkinsonism associated deglycase

acts_upstream_of_or_within

ISO

(PMID:15721235)

PMID:15721235

NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271

parkin RBR E3 ubiquitin protein ligase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

SLC6A2

solute carrier family 6 member 2

involved_in

IEA

GO_REF:0000118

NCBI chr16:35,885,756...35,935,638
Ensembl chr16:54,990,773...55,040,504

evoked excitatory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BEGAIN

brain enriched guanylate kinase associated

acts_upstream_of_or_within

ISO

(PMID:27785460)

PMID:27785460

NCBI chr14:81,157,642...81,209,503
Ensembl chr14:100,471,969...100,512,416

fragile X messenger ribonucleoprotein 1

ISO

PMID:36536454

RGD:401976434

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

evoked neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB3A, member RAS oncogene family

involved_in

IEA

GO_REF:0000107

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

excitatory chemical synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CHRDL1

chordin like 1

involved_in

IEA

GO_REF:0000107

NCBI chr X:99,781,730...99,915,778
Ensembl chr X:110,251,525...110,375,289

contactin associated protein 2

involved_in

ISO

(PMID:31141683), (PMID:31391512)
(PMID:30679017)

PMID:30679017 PMID:31141683 PMID:31391512

NCBI chr 7:137,858,607...140,150,820
Ensembl chr 7:150,345,240...152,626,818

fragile X messenger ribonucleoprotein 1

involved_in

ISO

(PMID:30679017)

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

GPRIN3

GPRIN family member 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:81,530,662...81,597,530
Ensembl chr 4:92,257,125...92,259,455

KCNQ2

potassium voltage-gated channel subfamily Q member 2

acts_upstream_of_or_within

ISO

(PMID:14762142)
(PMID:30382937)

PMID:14762142 PMID:30382937

Ensembl chr20:61,325,365...61,395,266

KCNQ3

potassium voltage-gated channel subfamily Q member 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 8:128,769,930...129,134,671
Ensembl chr 8:131,755,454...131,815,237

PDLIM4

PDZ and LIM domain 4

involved_in

ISO

PMID:15456832

PMID:15456832

RGD:13432260

NCBI chr 5:127,680,339...127,696,172
Ensembl chr 5:133,843,313...133,857,935

PTCHD1

patched domain containing 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr X:15,929,619...15,991,194
Ensembl chr X:23,305,555...23,366,273

PVALB

parvalbumin

involved_in

IEA

GO_REF:0000107

NCBI chr22:17,715,109...17,731,587
Ensembl chr22:35,551,448...35,568,316

SHISA6

shisa family member 6

involved_in

IEA

GO_REF:0000107

NCBI chr17:40,081,234...40,405,916
Ensembl chr17:44,836,825...45,154,241

SSH1

slingshot protein phosphatase 1

ISO

PMID:20442266

RGD:11535133

NCBI chr12:106,357,147...106,432,295
Ensembl chr12:109,758,399...109,823,444

TSC2

TSC complex subunit 2

involved_in

ISO

(PMID:30679017)

NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569

excitatory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A1 receptor

acts_upstream_of_or_within

ISO
IEA

PMID:19942300

GO_REF:0000107 RGD:2317911

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

adenosine A2a receptor

ISO

PMID:16644907

RGD:1625443

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

adrenoceptor beta 2

ISO

PMID:17175110

RGD:5129150

NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892

ATXN1

ataxin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:16,155,049...16,952,827
Ensembl chr 6:16,526,563...16,548,566

brain derived neurotrophic factor

ISO

PMID:17192436

RGD:1600576

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

cyclin dependent kinase 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

CELF4

CUGBP Elav-like family member 4

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr18:30,495,149...30,818,358
Ensembl chr18:34,068,123...34,374,372

CHRNA1

cholinergic receptor nicotinic alpha 1 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr2B:62,022,498...62,039,370
Ensembl chr2B:179,476,677...179,504,763

CHRNA10

cholinergic receptor nicotinic alpha 10 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr11:3,543,450...3,552,036
Ensembl chr11:3,651,580...3,656,780

cholinergic receptor nicotinic alpha 2 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr 8:26,729,767...26,749,277
Ensembl chr 8:23,932,846...23,952,377

cholinergic receptor nicotinic alpha 3 subunit

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:16162937)

MGI
GOC

PMID:16162937

GO_REF:0000108

NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044

cholinergic receptor nicotinic alpha 4 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005

cholinergic receptor nicotinic alpha 5 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr15:57,493,730...57,530,463
Ensembl chr15:76,455,165...76,486,376

CHRNA6

cholinergic receptor nicotinic alpha 6 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr 8:42,000,748...42,016,913
Ensembl chr 8:39,444,447...39,460,569

CHRNA9

cholinergic receptor nicotinic alpha 9 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr 4:34,654,043...34,675,984
Ensembl chr 4:40,509,475...40,528,869

CHRNB1

cholinergic receptor nicotinic beta 1 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr17:7,479,056...7,490,314
Ensembl chr17:7,465,229...7,476,099

cholinergic receptor nicotinic beta 2 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

CHRNB3

cholinergic receptor nicotinic beta 3 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr 8:41,947,062...41,987,159
Ensembl chr 8:39,391,001...39,429,926

CHRNB4

cholinergic receptor nicotinic beta 4 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr15:57,552,697...57,570,828
Ensembl chr15:76,515,455...76,532,712

CHRND

cholinergic receptor nicotinic delta subunit

involved_in

IEA

GO_REF:0000108

NCBI chr2B:119,757,722...119,768,254
Ensembl chr2B:238,676,495...238,686,987

CHRNE

cholinergic receptor nicotinic epsilon subunit

involved_in

IEA

GO_REF:0000108

NCBI chr17:4,944,046...4,950,288
Ensembl chr17:4,932,862...4,937,963

CHRNG

cholinergic receptor nicotinic gamma subunit

involved_in

IEA

GO_REF:0000108

NCBI chr2B:119,770,636...119,779,332
Ensembl chr2B:238,689,935...238,696,526

CKAP5

cytoskeleton associated protein 5

acts_upstream_of_or_within

ISO

(PMID:23936366)

PMID:23936366

NCBI chr11:46,694,967...46,797,500
Ensembl chr11:47,252,752...47,329,274

contactin associated protein 2

involved_in

ISO

(PMID:29300891)

PMID:29300891

NCBI chr 7:137,858,607...140,150,820
Ensembl chr 7:150,345,240...152,626,818

diacylglycerol kinase iota

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310

GHRL

ghrelin and obestatin prepropeptide

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

glycine receptor alpha 1

involved_in

IEA

GO_REF:0000108

NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567

GLRA2

glycine receptor alpha 2

involved_in

IEA

GO_REF:0000108

NCBI chr X:7,145,794...7,349,911
Ensembl chr X:14,430,441...14,634,973

GLRA3

glycine receptor alpha 3

involved_in

IEA

GO_REF:0000108

NCBI chr 4:166,865,061...167,045,844
Ensembl chr 4:179,083,211...179,279,232

GLRA4

glycine receptor alpha 4

involved_in

IEA

GO_REF:0000108

NCBI chr X:92,933,694...92,957,714
Ensembl chr X:103,317,486...103,338,910

GLRB

glycine receptor beta

involved_in

IEA

GO_REF:0000108

NCBI chr 4:149,422,654...149,518,669
Ensembl chr 4:161,236,610...161,333,035

GRID2

glutamate ionotropic receptor delta type subunit 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:84,663,030...86,170,778
Ensembl chr 4:95,339,460...96,807,748

glutamate ionotropic receptor kainate type subunit 1

acts_upstream_of_or_within

ISO

(PMID:11985817)
(PMID:11069933), (PMID:14715943), (PMID:14724198)

PMID:11069933 PMID:11985817 PMID:14715943 PMID:14724198

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

glutamate ionotropic receptor kainate type subunit 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:38,886,108...38,956,938
Ensembl chr19:47,389,804...47,544,604

glutamate ionotropic receptor NMDA type subunit 1

acts_upstream_of_or_within

ISO

(PMID:14645471)
(PMID:15003177)

PMID:14645471 PMID:15003177

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

glutamate ionotropic receptor NMDA type subunit 2A

acts_upstream_of_or_within

ISO
IEA

PMID:20164351

GO_REF:0000107 RGD:2325882

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

glutamate ionotropic receptor NMDA type subunit 2B

acts_upstream_of_or_within

ISO

(PMID:14645471)
(PMID:11530236), (PMID:12832518), (PMID:16045501), (PMID:16157280)
(PMID:10634899), (PMID:9147327)

PMID:9147327 PMID:10634899 PMID:11530236 PMID:12832518 PMID:14645471 More...

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

glutamate ionotropic receptor NMDA type subunit 2C

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:68,787,670...68,807,192

glutamate ionotropic receptor NMDA type subunit 2D

NOT|acts_upstream_of_or_within

ISO

(PMID:12832518)

PMID:12832518

NCBI chr19:45,392,258...45,447,004

HCRT

hypocretin neuropeptide precursor

ISO

PMID:16247802

RGD:1600968

NCBI chr17:15,130,581...15,132,024
Ensembl chr17:15,353,203...15,354,594

neuronal acetylcholine receptor subunit alpha-7

involved_in

IEA

GO_REF:0000108

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

leucine rich repeat kinase 2

involved_in

IEA

GO_REF:0000107

NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462

MAPK8IP2

mitogen-activated protein kinase 8 interacting protein 2

involved_in

IEA

GO_REF:0000107

NCBI chr22:30,846,613...30,857,737
Ensembl chr22:49,957,769...49,966,986

methyl-CpG binding protein 2

acts_upstream_of_or_within

ISO

(PMID:17920015)

PMID:17920015

NCBI chr X:143,571,864...143,647,192
Ensembl chr X:153,465,204...153,527,854

myocyte enhancer factor 2C

involved_in

ISO

(PMID:18599437), (PMID:18599438)

PMID:18599437 PMID:18599438

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

MET

MET proto-oncogene, receptor tyrosine kinase

involved_in

ISO

(PMID:21490227)

PMID:21490227

NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159

MPP2

MAGUK p55 scaffold protein 2

involved_in

IEA

GO_REF:0000107

NCBI chr17:13,487,459...13,519,978
Ensembl chr17:13,651,433...13,685,752

neuroligin 3

involved_in

ISO

(PMID:21808020)

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

neuronal PAS domain protein 4

involved_in

IEA

GO_REF:0000107

NCBI chr11:61,778,329...61,784,010
Ensembl chr11:65,103,097...65,108,825

NPFF

neuropeptide FF-amide peptide precursor

involved_in

ISO
IEA

PMID:10938301

GO_REF:0000118 RGD:2316571

NCBI chr12:35,245,172...35,246,710
Ensembl chr12:36,030,805...36,031,591

OPRM1

opioid receptor mu 1

ISO

PMID:18065149

RGD:2316604

NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251

P2RX1

purinergic receptor P2X 1

involved_in

IEA

GO_REF:0000108

NCBI chr17:3,944,636...3,965,260
Ensembl chr17:3,935,982...3,956,595

purinergic receptor P2X 2

involved_in

IEA

GO_REF:0000108

NCBI chr12:129,969,793...129,974,399

purinergic receptor P2X 3

involved_in

IEA

GO_REF:0000108

NCBI chr11:52,579,190...52,614,329
Ensembl chr 3:160,070,875...160,106,120

P2RX4

purinergic receptor P2X 4

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:16943557)

GOC
MGI

PMID:16943557

GO_REF:0000108

NCBI chr12:118,807,961...118,832,267
Ensembl chr12:122,178,672...122,202,959

P2RX5

purinergic receptor P2X 5

involved_in

IEA

GO_REF:0000108

NCBI chr17:3,722,117...3,745,833
Ensembl chr17:3,719,457...3,739,709

P2RX6

purinergic receptor P2X 6

involved_in

IEA

GO_REF:0000108

NCBI chr22:3,239,019...3,251,966
Ensembl chr22:19,728,644...19,741,078

P2RX7

purinergic receptor P2X 7

involved_in

IEA

GO_REF:0000108

NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068

protein phosphatase 1 regulatory subunit 9A

ISO

PMID:15473970

RGD:10043779

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

protein phosphatase 3 catalytic subunit alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394

RAB3 GTPase activating protein catalytic subunit 1

involved_in

ISO

(PMID:16782817)

NCBI chr2B:24,692,363...24,810,685
Ensembl chr2B:139,125,375...139,242,721

S1PR2

sphingosine-1-phosphate receptor 2

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr19:9,771,888...9,781,944
Ensembl chr19:10,436,502...10,437,563

SEZ6

seizure related 6 homolog

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:27,768,229...27,819,257
Ensembl chr17:28,301,359...28,327,354

SLC17A7

solute carrier family 17 member 7

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:46,443,076...46,455,195
Ensembl chr19:55,365,811...55,377,438

SLC29A1

solute carrier family 29 member 1 (Augustine blood group)

ISO

PMID:12611914

RGD:1299118

NCBI chr 6:43,815,006...43,830,290
Ensembl chr 6:45,099,243...45,113,689

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

fast, calcium ion-dependent exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

gamma-aminobutyric acid secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BEST1

bestrophin 1

involved_in

IEA

GO_REF:0000107

NCBI chr11:57,314,430...57,329,450
Ensembl chr11:60,672,835...60,687,417

neurofibromin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

ISO

(PMID:25242307)

PMID:25242307

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

glutamate secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCC8

ATP binding cassette subfamily C member 8

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870

KCNJ8

potassium inwardly rectifying channel subfamily J member 8

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:64,522,172...64,532,848
Ensembl chr12:67,127,263...67,137,128

neurofibromin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

ISO

(PMID:25242307)

PMID:25242307

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

glycine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC6A9

solute carrier family 6 member 9

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:43,298,326...43,333,345
Ensembl chr 1:44,664,839...44,704,882

induction of synaptic plasticity by chemical substance

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MAP1B

microtubule associated protein 1B

ISO

PMID:15374099

RGD:2304033

NCBI chr 5:43,102,739...43,204,978
Ensembl chr 5:43,701,530...43,803,393

inhibitory chemical synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

contactin associated protein 2

involved_in

ISO

(PMID:26511255), (PMID:31141683)
(PMID:30679017)

PMID:26511255 PMID:30679017 PMID:31141683

NCBI chr 7:137,858,607...140,150,820
Ensembl chr 7:150,345,240...152,626,818

fragile X messenger ribonucleoprotein 1

involved_in

ISO

(PMID:30679017)

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

KCNQ2

potassium voltage-gated channel subfamily Q member 2

acts_upstream_of_or_within

ISO

(PMID:30382937)

PMID:30382937

Ensembl chr20:61,325,365...61,395,266

KCNQ3

potassium voltage-gated channel subfamily Q member 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 8:128,769,930...129,134,671
Ensembl chr 8:131,755,454...131,815,237

PTCHD1

patched domain containing 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr X:15,929,619...15,991,194
Ensembl chr X:23,305,555...23,366,273

PVALB

parvalbumin

involved_in

IEA

GO_REF:0000107

NCBI chr22:17,715,109...17,731,587
Ensembl chr22:35,551,448...35,568,316

TSC2

TSC complex subunit 2

involved_in

ISO

(PMID:30679017)

NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569

inhibitory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A2a receptor

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

ADRB1

adrenoceptor beta 1

ISO

PMID:18262504

RGD:5129137

NCBI chr10:110,642,491...110,646,595

brain derived neurotrophic factor

acts_upstream_of_or_within

ISO

(PMID:24201284)

PMID:24201284

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

cholinergic receptor nicotinic alpha 4 subunit

acts_upstream_of_or_within

ISO

(PMID:17146052)

PMID:17146052

NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005

CX3CL1

C-X3-C motif chemokine ligand 1

ISO

PMID:19748551

RGD:4891944

NCBI chr16:37,646,447...37,659,078
Ensembl chr16:56,779,065...56,791,760

dopamine receptor D4

acts_upstream_of_or_within

ISO

(PMID:14684868)
(PMID:11356863)

PMID:11356863 PMID:14684868

NCBI chr11:640,401...646,775

GABRB3

gamma-aminobutyric acid type A receptor subunit beta3

involved_in

IEA

GO_REF:0000107

NCBI chr15:3,129,481...3,357,495
Ensembl chr15:23,981,359...24,058,357

glycine receptor alpha 1

acts_upstream_of_or_within
involved_in

IEA
ISO

(PMID:24801766)

PMID:24801766

GO_REF:0000107

NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567

glutamate ionotropic receptor kainate type subunit 1

acts_upstream_of_or_within

ISO

(PMID:11144357)
(PMID:12223554)

PMID:11144357 PMID:12223554

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

INSYN1

inhibitory synaptic factor 1

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr15:52,650,196...52,663,270
Ensembl chr15:71,405,502...71,418,269

INSYN2A

inhibitory synaptic factor 2A

involved_in

IEA

GO_REF:0000118

NCBI chr10:123,716,226...123,777,268
Ensembl chr10:127,972,818...128,033,414

neuroligin 1

NOT|involved_in

ISO

PMID:17582332
(PMID:17582332)

PMID:17582332

RGD:8553502

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

PMID:17823315 PMID:19406211 PMID:21808020

neuroligin 3

involved_in
acts_upstream_of_or_within

ISO

PMID:19406211
(PMID:21808020)
(PMID:17823315)

BHF-UCL
CACAO
MGI

RGD:8554851

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

neuronal PAS domain protein 4

acts_upstream_of_or_within
involved_in

IEA
ISO

(PMID:18815592), (PMID:24855953)

PMID:18815592 PMID:24855953

GO_REF:0000107

NCBI chr11:61,778,329...61,784,010
Ensembl chr11:65,103,097...65,108,825

long-term synaptic depression

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABHD6

abhydrolase domain containing 6, acylglycerol lipase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:58,172,334...58,227,531
Ensembl chr 3:59,586,573...59,641,824

adenosine A1 receptor

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

ARF1

ARF GTPase 1

involved_in

ISO

PMID:23889934

PMID:23889934

RGD:8553918

NCBI chr 1:203,484,803...203,501,395
Ensembl chr 1:208,695,615...208,712,105

CD38

CD38 molecule

ISO

PMID:10097163

RGD:2307271

NCBI chr 4:10,228,803...10,295,129
Ensembl chr 4:15,525,835...15,587,677

dopamine receptor D1

acts_upstream_of_or_within

ISO

(PMID:14981263)

PMID:14981263

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

DRD5

dopamine receptor D5

acts_upstream_of_or_within

ISO

(PMID:13679419)

PMID:13679419

NCBI chr 4:4,189,536...4,193,144
Ensembl chr 4:9,509,094...9,510,527

glutamate ionotropic receptor AMPA type subunit 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660

GRID2IP

Grid2 interacting protein

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:6,892,842...6,956,615
Ensembl chr 7:6,690,498...6,744,194

GRM2

glutamate metabotropic receptor 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:51,639,792...51,652,779
Ensembl chr 3:52,873,144...52,884,395

MGLL

monoglyceride lipase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:124,733,770...124,865,302
Ensembl chr 3:132,040,430...132,171,731

polo like kinase 2

involved_in

ISO

PMID:21382555

NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793

POLR2F

RNA polymerase II, I and III subunit F

involved_in

ISO

PMID:21252856

PMID:21252856

RGD:8554238

NCBI chr22:18,868,872...18,988,918
Ensembl chr22:36,796,015...36,814,469

PRRT1

proline rich transmembrane protein 1

involved_in

IEA

GO_REF:0000107

NCBI chr 6:31,795,267...31,798,873
Ensembl chr 6:32,675,369...32,679,109

phosphatase and tensin homolog

ISO

NMDA receptor-dependent

PMID:20628354

RGD:4144068

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

protein tyrosine kinase 2 beta

ISO

PMID:20826662

RGD:10041066

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

SHANK2

SH3 and multiple ankyrin repeat domains 2

involved_in

ISO

(PMID:22699620)

PMID:22699620

NCBI chr11:65,570,677...66,268,139
Ensembl chr11:68,860,606...69,437,925

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21795692)

PMID:21795692

NCBI chr22:30,951,866...30,973,608

SLC24A1

solute carrier family 24 member 1

involved_in

IEA

GO_REF:0000118

NCBI chr15:44,552,886...44,597,640
Ensembl chr15:62,831,987...62,882,431

SLC24A2

solute carrier family 24 member 2

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 9:19,317,132...19,593,503
Ensembl chr 9:19,814,244...20,249,225

SORCS2

sortilin related VPS10 domain containing receptor 2

involved_in

IEA

GO_REF:0000107

Ensembl chr 4:7,259,337...7,803,594

SRF

serum response factor

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768

syntaxin binding protein 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

VPS13A

vacuolar protein sorting 13 homolog A

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 9:47,424,921...47,668,150
Ensembl chr 9:76,032,286...76,269,636

long-term synaptic potentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B-Raf proto-oncogene, serine/threonine kinase

acts_upstream_of_or_within

ISO

(PMID:16342120)

PMID:16342120

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

CAMK2B

calcium/calmodulin dependent protein kinase II beta

acts_upstream_of_or_within

ISO

PMID:2549638

PMID:2549638

RGD:8553576

NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342

CC2D1A

coiled-coil and C2 domain containing 1A

acts_upstream_of_or_within

ISO

(PMID:26826102)

PMID:26826102

NCBI chr19:13,468,650...13,493,308

chordin

involved_in

ISO

(PMID:17634368)

NCBI chr 3:181,417,140...181,460,236
Ensembl chr 3:189,898,856...189,908,573

CKAP5

cytoskeleton associated protein 5

acts_upstream_of_or_within

ISO

(PMID:23936366)

PMID:23936366

NCBI chr11:46,694,967...46,797,500
Ensembl chr11:47,252,752...47,329,274

CRH

corticotropin releasing hormone

ISO

PMID:20807310

RGD:5491009

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

CRHR1

corticotropin releasing hormone receptor 1

ISO

PMID:19376201

RGD:5130954

NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208

CRHR2

corticotropin releasing hormone receptor 2

involved_in

ISO
IEA

PMID:17004937 PMID:19376201

GO_REF:0000118 RGD:5130954 RGD:5131266

NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220

DBI

diazepam binding inhibitor, acyl-CoA binding protein

acts_upstream_of_or_within

ISO

(PMID:17150371)

PMID:17150371

NCBI chr2B:6,309,048...6,314,660
Ensembl chr2B:119,887,728...119,892,986

dopamine receptor D1

acts_upstream_of_or_within

ISO

(PMID:14981263), (PMID:9427321)
(PMID:13679419)

PMID:9427321 PMID:13679419 PMID:14981263

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

EGR1

early growth response 1

ISO

PMID:21425206

RGD:5131650

NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

ISO

(PMID:31730234)

PMID:31730234

NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644

GFAP

glial fibrillary acidic protein

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:12,407,211...12,417,072
Ensembl chr17:12,579,754...12,591,961

GIP

gastric inhibitory polypeptide

ISO

PMID:18234983

RGD:2312531

NCBI chr17:8,573,104...8,580,424

glutamate ionotropic receptor AMPA type subunit 1

ISO

PMID:26088419

RGD:11096590

NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660

GRIA3

glutamate ionotropic receptor AMPA type subunit 3

involved_in

ISO

(PMID:28103481)

PMID:28103481

NCBI chr X:112,380,229...112,687,740
Ensembl chr X:122,562,330...122,870,130

glutamate ionotropic receptor NMDA type subunit 2A

acts_upstream_of_or_within

ISO
IEA

PMID:26088419

GO_REF:0000107 RGD:11096590

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

glutamate ionotropic receptor NMDA type subunit 2B

acts_upstream_of_or_within

ISO

(PMID:16901514)
(PMID:20661302)

PMID:16901514 PMID:20661302 PMID:26088419

RGD:11096590

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785

HTR6

5-hydroxytryptamine receptor 6

ISO

PMID:19660530

RGD:2316998

NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680

HTR7

5-hydroxytryptamine receptor 7

ISO

PMID:22314569

RGD:6480664

NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158

ITPR3

inositol 1,4,5-trisphosphate receptor type 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:33,194,531...33,269,788
Ensembl chr 6:34,303,454...34,378,215

LARGE xylosyl- and glucuronyltransferase 1

acts_upstream_of_or_within

ISO

(PMID:29915039)

PMID:29915039

NCBI chr22:14,077,463...14,929,250

LRRTM1

leucine rich repeat transmembrane neuronal 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2A:80,376,582...80,392,899
Ensembl chr2A:81,953,891...81,955,459

LRRTM2

leucine rich repeat transmembrane neuronal 2

acts_upstream_of_or_within

ISO

(PMID:23931994)

PMID:23931994

NCBI chr 5:134,247,933...134,254,188

MAPK1

mitogen-activated protein kinase 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335

methyl-CpG binding protein 2

acts_upstream_of_or_within

ISO

(PMID:16087343)

PMID:16087343

NCBI chr X:143,571,864...143,647,192
Ensembl chr X:153,465,204...153,527,854

MIR320A

microRNA mir-320a

involved_in

IEA

GO_REF:0000115

NCBI chr 8:21,489,843...21,489,896

MIR320A

microRNA 320a

involved_in

IEA

GO_REF:0000115

Ensembl chr 8:18,428,865...18,428,946

MIR320B-1

microRNA mir-320b-1

involved_in

IEA

GO_REF:0000115

NCBI chr 1:85,848,191...85,848,240

MIR320B-2

microRNA mir-320b-2

involved_in

IEA

GO_REF:0000115

NCBI chr 1:199,725,084...199,725,132

MIR320B1

microRNA 320b-1

involved_in

IEA

GO_REF:0000115

Ensembl chr 1:120,845,470...120,845,548

MIR320B2

microRNA 320b-2

involved_in

IEA

GO_REF:0000115

Ensembl chr 1:204,734,018...204,734,155

MIR320C2

microRNA 320c-2

involved_in

IEA

GO_REF:0000115

Ensembl chr18:21,197,322...21,197,371

MIR320D2

microRNA 320d-2

involved_in

IEA

GO_REF:0000115

Ensembl chr X:140,455,699...140,455,746

MIR320E

microRNA 320e

involved_in

IEA

GO_REF:0000115

Ensembl chr19:52,230,883...52,230,935

MIR324

microRNA 324

involved_in

IEA

GO_REF:0000115

Ensembl chr17:7,240,448...7,240,530

MIR337

microRNA 337

involved_in

IEA

GO_REF:0000115

Ensembl chr14:100,806,143...100,806,235

MIR342

microRNA mir-342

involved_in

IEA

GO_REF:0000115

NCBI chr14:80,732,883...80,732,947

MIR342

microRNA 342

involved_in

IEA

GO_REF:0000115

Ensembl chr14:100,049,826...100,049,921

MIR421

microRNA 421

involved_in

IEA

GO_REF:0000115

Ensembl chr X:73,591,224...73,591,308

MIR433

microRNA 433

involved_in

IEA

GO_REF:0000115

Ensembl chr14:100,813,401...100,813,493

MIR541

microRNA 541

involved_in

IEA

GO_REF:0000115

Ensembl chr14:100,998,766...100,998,849

MIR95

microRNA mir-95

involved_in

IEA

GO_REF:0000115

Ensembl chr 4:8,069,273...8,069,353

MPP2

MAGUK p55 scaffold protein 2

involved_in

IEA

GO_REF:0000107

NCBI chr17:13,487,459...13,519,978
Ensembl chr17:13,651,433...13,685,752

MUSK

muscle associated receptor tyrosine kinase

ISO

PMID:16870737

RGD:2317092

NCBI chr 9:81,814,766...81,947,341
Ensembl chr 9:109,980,748...110,107,480

neurofibromin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

NFATC4

nuclear factor of activated T cells 4

involved_in

IEA

GO_REF:0000107

NCBI chr14:5,141,699...5,156,021
Ensembl chr14:23,266,702...23,279,249

neuroligin 1

ISO

PMID:23083734

RGD:9831154

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

neuroligin 3

involved_in

ISO

(PMID:21808020)

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

noggin

involved_in

IEA

GO_REF:0000107

NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092

neuroplastin

involved_in

ISO

PMID:16925595

PMID:16925595

RGD:8554143

NCBI chr15:52,470,545...52,544,046
Ensembl chr15:71,229,992...71,269,579

NR2E1

nuclear receptor subfamily 2 group E member 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:105,965,478...105,988,213
Ensembl chr 6:109,831,223...109,851,436

neurotrophic receptor tyrosine kinase 2

involved_in

IEA

GO_REF:0000107

NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678

polo like kinase 2

involved_in

ISO

PMID:21382555

NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793

protein kinase C gamma

ISO

PMID:10501452

RGD:28867228

NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977

PRKCZ

protein kinase C zeta

involved_in

ISO

PMID:11914719

PMID:11914719

RGD:8554098

NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855

PRRT1

proline rich transmembrane protein 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:31,795,267...31,798,873
Ensembl chr 6:32,675,369...32,679,109

phosphatase and tensin homolog

involved_in

ISO

(PMID:18082964)

PMID:18082964

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

protein tyrosine kinase 2 beta

involved_in

ISO

PMID:11239437

PMID:11239437

RGD:8553497

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

pleiotrophin

ISO

PMID:8904779

RGD:9831451

NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623

RASGRF2

Ras protein specific guanine nucleotide releasing factor 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:34,048,832...34,326,755
Ensembl chr 5:34,359,896...34,635,488

reelin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037

RGS14

regulator of G protein signaling 14

involved_in

IEA

GO_REF:0000107

NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453

regulating synaptic membrane exocytosis 1

ISO

PMID:21849565

RGD:5686386

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

S100B

S100 calcium binding protein B

ISO

PMID:21546003

RGD:5508826

NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953

SERPINE2

serpin family E member 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040

SHANK2

SH3 and multiple ankyrin repeat domains 2

involved_in

ISO

(PMID:22699620)

PMID:22699620

NCBI chr11:65,570,677...66,268,139
Ensembl chr11:68,860,606...69,437,925

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21558424)

PMID:21558424

NCBI chr22:30,951,866...30,973,608

SLC1A1

solute carrier family 1 member 1

acts_upstream_of_or_within
involved_in

IEA
ISO

(PMID:29229708)

PMID:29229708

GO_REF:0000107

NCBI chr 9:4,323,124...4,420,193
Ensembl chr 9:4,511,491...4,608,337

SLC24A1

solute carrier family 24 member 1

involved_in

IEA

GO_REF:0000118

NCBI chr15:44,552,886...44,597,640
Ensembl chr15:62,831,987...62,882,431

SLC24A2

solute carrier family 24 member 2

involved_in
acts_upstream_of_or_within

IEA

PMID:21593315 PMID:29274751

GO_REF:0000107 GO_REF:0000118

NCBI chr 9:19,317,132...19,593,503
Ensembl chr 9:19,814,244...20,249,225

SLC8A2

solute carrier family 8 member A2

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:29274751)

Ensembl
ARUK-UCL

PMID:29274751

GO_REF:0000107

NCBI chr19:44,420,146...44,464,242
Ensembl chr19:53,077,857...53,113,830

SLC8A3

solute carrier family 8 member A3

involved_in
acts_upstream_of_or_within

ISO

(PMID:21593315)
(PMID:29274751)

UniProt
ARUK-UCL

NCBI chr14:50,634,091...50,779,712

SLITRK4

SLIT and NTRK like family member 4

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr X:132,750,454...132,763,782
Ensembl chr X:143,138,515...143,141,028

synaptosome associated protein 25

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SNAP47

synaptosome associated protein 47

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:203,128,827...203,181,521
Ensembl chr 1:208,115,118...208,161,139

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

STX3

syntaxin 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:54,976,575...55,027,638
Ensembl chr11:58,426,894...58,476,417

STX4

syntaxin 4

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,917,576...23,933,884
Ensembl chr16:31,400,915...31,411,364

synaptotagmin 12

involved_in

IEA

GO_REF:0000107

NCBI chr11:62,383,485...62,412,451
Ensembl chr11:65,709,808...65,733,010

tenascin R

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:150,826,892...151,257,301
Ensembl chr 1:154,532,582...154,615,538

TSHZ3

teashirt zinc finger homeobox 3

involved_in

ISO

(PMID:27668656)

PMID:27668656

NCBI chr19:28,195,740...28,270,265
Ensembl chr19:36,946,685...37,021,531

unc-13 homolog A

ISO

PMID:21849565

RGD:5686386

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

VAMP2

vesicle associated membrane protein 2

acts_upstream_of_or_within

ISO

(PMID:23395379)

PMID:23395379

NCBI chr17:43,495,464...43,499,348
Ensembl chr17:48,228,253...48,231,948

modification of synaptic structure, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MMP9

matrix metallopeptidase 9

involved_in

ISO

PMID:19047646

PMID:19047646

RGD:405650393

NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129

modulation of chemical synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABR

ABR activator of RhoGEF and GTPase

involved_in

ISO

(PMID:20962234)

PMID:20962234

NCBI chr17:972,009...1,174,953
Ensembl chr17:895,013...1,069,973

ADCY1

adenylate cyclase 1

involved_in

IEA

GO_REF:0000107

NCBI chr 7:46,289,042...46,436,839
Ensembl chr 7:46,354,640...46,492,549

adenylate cyclase 8

involved_in

IEA

GO_REF:0000107

NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073

AKAP12

A-kinase anchoring protein 12

involved_in

IEA

GO_REF:0000107

NCBI chr 6:149,058,350...149,176,710
Ensembl chr 6:153,757,081...153,873,925

AKAP7

A-kinase anchoring protein 7

involved_in

IEA

GO_REF:0000107

NCBI chr 6:128,936,583...129,084,018
Ensembl chr 6:133,043,403...133,190,745

activity regulated cytoskeleton associated protein

involved_in

IEA

Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr 8:139,320,366...139,323,802
Ensembl chr 8:142,367,995...142,369,185

ARHGAP44

Rho GTPase activating protein 44

involved_in

IEA

GO_REF:0000107

NCBI chr17:38,657,824...38,859,591
Ensembl chr17:43,357,438...43,453,457

ARRB2

arrestin beta 2

involved_in

IEA

GO_REF:0000107

NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517

BACE1

beta-secretase 1

involved_in

IEA

GO_REF:0000107

NCBI chr11:112,120,950...112,151,505
Ensembl chr11:116,054,303...116,084,812

BAIAP2

BAR/IMD domain containing adaptor protein 2

involved_in

IEA

GO_REF:0000107

NCBI chr17:75,460,491...75,542,700
Ensembl chr17:81,187,021...81,269,714

BAIAP3

BAI1 associated protein 3

involved_in

IEA

GO_REF:0000107

Ensembl chr16:1,390,160...1,403,978

BCR

BCR activator of RhoGEF and GTPase

involved_in

ISO

(PMID:20962234)

PMID:20962234

brain derived neurotrophic factor

involved_in

IEA

GO_REF:0000118

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

BSN

bassoon presynaptic cytomatrix protein

involved_in

ISO

PMID:21700703

PMID:21700703

RGD:401966870

NCBI chr 3:49,483,652...49,603,928
Ensembl chr 3:50,790,552...50,841,178

BTBD9

BTB domain containing 9

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 6:37,733,575...38,211,857
Ensembl chr 6:38,928,879...39,358,424

calcium voltage-gated channel subunit alpha1 A

involved_in

IEA

GO_REF:0000107

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

calcium voltage-gated channel subunit alpha1 B

involved_in

ISO

(PMID:23376566)

PMID:23376566

NCBI chr 9:108,989,621...109,256,841

CAMKV

CaM kinase like vesicle associated

involved_in

IEA

GO_REF:0000107

NCBI chr 3:49,789,838...49,801,795
Ensembl chr 3:51,026,111...51,038,064

CDH11

cadherin 11

involved_in

IEA

GO_REF:0000107

NCBI chr16:45,261,269...45,436,597
Ensembl chr16:64,367,862...64,475,028

CDH2

cadherin 2

involved_in

ISO

PMID:9655504

PMID:9655504

RGD:12050123

NCBI chr18:21,210,001...21,435,919
Ensembl chr18:24,812,019...25,008,325

CDKL5

cyclin dependent kinase like 5

involved_in

IEA

GO_REF:0000107

NCBI chr X:11,047,357...11,261,172
Ensembl chr X:18,492,329...18,638,735

CFL1

cofilin 1

involved_in

ISO

PMID:16025109

PMID:16025109

RGD:13702428

NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806

CHMP2B

charged multivesicular body protein 2B

involved_in

ISO

PMID:25698751

PMID:25698751

RGD:13702150

NCBI chr 3:87,358,297...87,386,556
Ensembl chr 3:89,471,993...89,501,241

CNTNAP4

contactin associated protein family member 4

involved_in

ISO

(PMID:24870235)

PMID:24870235

NCBI chr16:56,512,541...57,138,499
Ensembl chr16:76,199,706...76,484,466

CSPG5

chondroitin sulfate proteoglycan 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:47,464,341...47,482,910
Ensembl chr 3:48,564,199...48,580,048

CX3CR1

C-X3-C motif chemokine receptor 1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219

DGKB

diacylglycerol kinase beta

involved_in

IEA

GO_REF:0000107

NCBI chr 7:14,803,023...15,638,280
Ensembl chr 7:14,165,933...14,969,825

DGKE

diacylglycerol kinase epsilon

involved_in

IEA

GO_REF:0000107

NCBI chr17:50,912,079...50,946,655
Ensembl chr17:55,773,896...55,802,485

DLGAP1

DLG associated protein 1

involved_in

ISO

PMID:22328512

PMID:22328512

RGD:13702373

NCBI chr18:9,816,171...10,781,490
Ensembl chr18:12,704,306...13,091,118

DLGAP2

DLG associated protein 2

involved_in

ISO

(PMID:25071926)

PMID:25071926

NCBI chr 8:5,661,423...6,661,559
Ensembl chr 8:759,261...1,596,858

DLGAP3

DLG associated protein 3

involved_in

IEA

GO_REF:0000107

NCBI chr 1:34,131,692...34,195,856
Ensembl chr 1:35,314,112...35,352,982

DNM1

dynamin 1

involved_in

ISO

(PMID:24643165)

PMID:24643165

NCBI chr 9:99,324,385...99,376,262
Ensembl chr 9:128,004,508...128,044,690

dopamine receptor D2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

EIF4EBP2

eukaryotic translation initiation factor 4E binding protein 2

involved_in

ISO

(PMID:23172145)
(PMID:20347422)

PMID:20347422 PMID:23172145

NCBI chr10:66,879,744...66,903,027
Ensembl chr10:69,406,745...69,423,249

EPHA7

EPH receptor A7

involved_in

IEA

GO_REF:0000107

NCBI chr 6:91,143,240...91,322,040
Ensembl chr 6:94,392,353...94,566,716

EPHB1

EPH receptor B1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:131,841,459...132,309,082
Ensembl chr 3:139,313,387...139,776,802

FYN

FYN proto-oncogene, Src family tyrosine kinase

involved_in

IEA

GO_REF:0000107

NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451

GABRR1

gamma-aminobutyric acid type A receptor subunit rho1

involved_in

IEA

GO_REF:0000107

NCBI chr 6:87,052,479...87,092,665
Ensembl chr 6:90,327,562...90,367,938

GLRA2

glycine receptor alpha 2

involved_in

IEA

GO_REF:0000107

NCBI chr X:7,145,794...7,349,911
Ensembl chr X:14,430,441...14,634,973

GNAI2

G protein subunit alpha i2

involved_in

IEA

GO_REF:0000107

NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988

GPER1

G protein-coupled estrogen receptor 1

involved_in

ISO

(PMID:29421611)

PMID:29421611

NCBI chr 7:1,331,586...1,338,194

glutamate ionotropic receptor AMPA type subunit 1

involved_in

ISO

PMID:11348590

PMID:11348590

RGD:8553683

NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660

GRIA4

glutamate ionotropic receptor AMPA type subunit 4

involved_in

ISO

PMID:11036266

PMID:11036266

RGD:8554601

NCBI chr11:100,498,632...100,873,764
Ensembl chr11:103,983,862...104,355,280

glutamate ionotropic receptor kainate type subunit 2

involved_in

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

glutamate ionotropic receptor NMDA type subunit 2A

involved_in

IEA

GO_REF:0000107

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

GRM3

glutamate metabotropic receptor 3

ISO

PMID:12694929

RGD:1298935

NCBI chr 7:78,621,634...78,842,532
Ensembl chr 7:92,400,728...92,500,553

glutamate metabotropic receptor 5

involved_in

IEA

GO_REF:0000107

NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953

HNRNPK

heterogeneous nuclear ribonucleoprotein K

involved_in

ISO

PMID:24990929

PMID:24990929

RGD:10002784

NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756

IGSF8

immunoglobulin superfamily member 8

involved_in

ISO

(PMID:33057002)

PMID:33057002

NCBI chr 1:135,445,180...135,452,684
Ensembl chr 1:139,366,228...139,374,732

IQSEC2

IQ motif and Sec7 domain ArfGEF 2

involved_in

IEA

GO_REF:0000107

NCBI chr X:45,447,977...45,535,836
Ensembl chr X:53,557,563...53,644,737

ITGB1

integrin subunit beta 1

involved_in

ISO

(PMID:17065460)

PMID:17065460

NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031

JAK2

Janus kinase 2

involved_in

ISO

PMID:22284190

PMID:22284190

RGD:13702421

NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626

KCNN2

potassium calcium-activated channel subfamily N member 2

involved_in

ISO

(PMID:26166566)

PMID:26166566

NCBI chr 5:109,722,916...109,862,747
Ensembl chr 5:115,522,443...115,661,079

L1CAM

L1 cell adhesion molecule

involved_in

ISO

PMID:7997264

PMID:7997264

RGD:13702438

NCBI chr X:143,412,303...143,437,090
Ensembl chr X:153,298,690...153,324,228

neuronal acetylcholine receptor subunit alpha-7

involved_in

ISO

(PMID:20943921)

PMID:20943921

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

LOC100983617

protocadherin-8

involved_in

ISO

PMID:10383464

PMID:10383464

RGD:68758

NCBI chr13:33,880,543...33,886,243
Ensembl chr13:52,688,522...52,692,399

LOC100994646

neuroligin-4, Y-linked

involved_in

IEA

GO_REF:0000107

Ensembl chr X:5,756,699...6,018,008

LRFN2

leucine rich repeat and fibronectin type III domain containing 2

involved_in

IEA

GO_REF:0000107

NCBI chr 6:39,972,362...40,167,612
Ensembl chr 6:41,282,940...41,477,073

LRP8

LDL receptor related protein 8

involved_in

IEA

GO_REF:0000107

NCBI chr 1:52,515,534...52,600,390
Ensembl chr 1:54,114,909...54,199,452

LRRC4

leucine rich repeat containing 4

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 7:120,018,613...120,022,973
Ensembl chr 7:132,671,114...132,676,378

LRRC4C

leucine rich repeat containing 4C

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr11:40,094,944...41,451,184
Ensembl chr11:40,486,482...40,488,404

MAPK3

mitogen-activated protein kinase 3

involved_in

IEA

GO_REF:0000107

Ensembl chr16:30,489,362...30,498,017

MAPK8

mitogen-activated protein kinase 8

involved_in

ISO

(PMID:17284179)

PMID:17284179

NCBI chr10:45,806,748...45,936,362

MAPK9

mitogen-activated protein kinase 9

involved_in

IEA

GO_REF:0000107

NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135

MET

MET proto-oncogene, receptor tyrosine kinase

involved_in

ISO

(PMID:21490227)

PMID:21490227

NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159

MYO5B

myosin VB

involved_in

ISO

(PMID:18984164)

PMID:18984164

NCBI chr18:43,207,387...43,575,951
Ensembl chr18:46,555,259...46,786,223

NCAM1

neural cell adhesion molecule 1

involved_in

ISO

PMID:7997264

PMID:7997264

RGD:13702438

NCBI chr11:107,845,507...108,160,441
Ensembl chr11:111,925,677...112,000,401

NCAN

neurocan

involved_in

ISO

(PMID:11486035)

PMID:11486035

NCBI chr19:18,650,522...18,690,882
Ensembl chr19:19,657,766...19,691,998

neuroligin 1

acts_upstream_of_or_within
involved_in

IEA
ISO

PMID:25428619

Ensembl
ARUK-UCL

PMID:25428619

GO_REF:0000107 RGD:11554338

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

neuroligin 2

acts_upstream_of_or_within

ISO

(PMID:16982420)

PMID:16982420

NCBI chr17:7,438,853...7,454,014

neuroligin 3

acts_upstream_of_or_within

ISO

(PMID:16982420)

PMID:16982420

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

NLGN4X

neuroligin 4 X-linked

involved_in

IEA

GO_REF:0000107

Ensembl chr X:5,756,699...6,018,008

neuroplastin

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr15:52,470,545...52,544,046
Ensembl chr15:71,229,992...71,269,579

NRG3

neuregulin 3

involved_in

IEA

GO_REF:0000107

NCBI chr10:78,267,693...79,384,895
Ensembl chr10:81,862,036...82,973,334

NTF3

neurotrophin 3

involved_in

ISO
IEA

PMID:14507970

GO_REF:0000118 RGD:1358327

NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989

NTF4

neurotrophin 4

involved_in

IEA

GO_REF:0000118

Ensembl chr19:54,995,009...54,995,641

NTNG1

netrin G1

involved_in

IEA

GO_REF:0000107

NCBI chr 1:109,666,955...110,012,880
Ensembl chr 1:108,790,654...109,127,016

NTNG2

netrin G2

involved_in

IEA

GO_REF:0000107

NCBI chr 9:103,281,915...103,362,786
Ensembl chr 9:131,917,760...131,998,107

NXPH1

neurexophilin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 7:9,159,585...9,472,699
Ensembl chr 7:8,511,688...8,822,387

NXPH4

neurexophilin 4

involved_in

IEA

GO_REF:0000107

NCBI chr12:31,700,935...31,710,526
Ensembl chr12:31,953,259...31,962,757

purinergic receptor P2X 3

involved_in

IEA

GO_REF:0000107

NCBI chr11:52,579,190...52,614,329
Ensembl chr 3:160,070,875...160,106,120

PACSIN2

protein kinase C and casein kinase substrate in neurons 2

involved_in

IEA

GO_REF:0000107

NCBI chr22:23,757,565...23,900,837
Ensembl chr22:41,908,922...41,999,692

PAFAH1B1

platelet activating factor acetylhydrolase 1b regulatory subunit 1

involved_in

IEA

GO_REF:0000107

NCBI chr17:2,584,349...2,676,928
Ensembl chr17:2,590,007...2,680,994

PATE4

prostate and testis expressed 4

acts_upstream_of_or_within

ISO

(PMID:18387948)

PMID:18387948

NCBI chr11:120,651,794...120,659,020
Ensembl chr11:124,565,341...124,572,090

PDE4A

phosphodiesterase 4A

involved_in

ISO

PMID:27559174

PMID:27559174

RGD:13702343

NCBI chr19:9,956,019...10,020,538
Ensembl chr19:10,632,273...10,681,944

PFN1

profilin 1

involved_in

ISO

(PMID:26951674)

PMID:26951674

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

PFN2

profilin 2

involved_in

ISO

(PMID:26951674)

PMID:26951674

NCBI chr 3:146,986,364...146,992,558

PLCB4

phospholipase C beta 4

involved_in

IEA

GO_REF:0000107

NCBI chr20:9,042,127...9,454,207
Ensembl chr20:9,192,061...9,456,443

PLCG1

phospholipase C gamma 1

involved_in

ISO

(PMID:28138157)

PMID:28138157

NCBI chr20:37,477,077...37,515,854
Ensembl chr20:38,572,709...38,615,145

PLPPR4

phospholipid phosphatase related 4

involved_in

IEA

GO_REF:0000107

NCBI chr 1:101,919,714...101,965,146
Ensembl chr 1:100,640,187...100,685,483

protein phosphatase 1 regulatory subunit 9A

involved_in

IEA

GO_REF:0000107

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

protein phosphatase 3 catalytic subunit alpha

acts_upstream_of_or_within
involved_in

IEA
ISO

(PMID:10200317)

PMID:10200317

GO_REF:0000107

NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394

protein kinase cAMP-activated catalytic subunit alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205

PRKAR1B

protein kinase cAMP-dependent type I regulatory subunit beta

involved_in

IEA

GO_REF:0000107

NCBI chr 7:700,691...876,497
Ensembl chr 7:923,668...1,097,456

PRKAR2A

protein kinase cAMP-dependent type II regulatory subunit alpha

involved_in

ISO

(PMID:15255994)

PMID:15255994

NCBI chr 3:48,665,421...48,774,111
Ensembl chr 3:49,747,611...49,854,382

PRKAR2B

protein kinase cAMP-dependent type II regulatory subunit beta

involved_in

IEA

GO_REF:0000107

NCBI chr 7:99,021,209...99,140,652
Ensembl chr 7:111,748,463...111,866,044

parkin RBR E3 ubiquitin protein ligase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

pleiotrophin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623

PTPRA

protein tyrosine phosphatase receptor type A

involved_in

ISO

(PMID:12912911)

PMID:12912911

NCBI chr20:2,962,701...3,125,282
Ensembl chr20:2,801,905...2,888,195

PTPRD

protein tyrosine phosphatase receptor type D

involved_in

IEA

GO_REF:0000107

NCBI chr 9:8,113,171...10,420,732
Ensembl chr 9:8,288,569...8,831,227

PTPRS

protein tyrosine phosphatase receptor type S

involved_in

IEA

GO_REF:0000107

NCBI chr19:4,227,038...4,361,958
Ensembl chr19:5,168,599...5,247,778

PXK

PX domain containing serine/threonine kinase like

involved_in

IEA

GO_REF:0000107

NCBI chr 3:58,265,626...58,358,247
Ensembl chr 3:59,711,749...59,773,556

reelin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037

RGS14

regulator of G protein signaling 14

involved_in

IEA

GO_REF:0000107

NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453

ROR2

receptor tyrosine kinase like orphan receptor 2

involved_in

ISO

PMID:26311509

PMID:26311509

RGD:11353570

NCBI chr 9:62,782,183...63,005,626
Ensembl chr 9:90,851,983...90,965,084

RPS6KB1

ribosomal protein S6 kinase B1

involved_in

IEA

GO_REF:0000107

NCBI chr17:53,958,807...54,014,752
Ensembl chr17:58,799,069...58,853,653

RTN4

reticulon 4

involved_in

ISO

(PMID:30040841)

PMID:30040841

NCBI chr2A:55,129,272...55,207,031

SHANK1

SH3 and multiple ankyrin repeat domains 1

involved_in

IEA

GO_REF:0000107

NCBI chr19:47,623,474...47,684,476
Ensembl chr19:56,526,577...56,580,442

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:27161151)

PMID:27161151

NCBI chr22:30,951,866...30,973,608

SLC4A8

solute carrier family 4 member 8

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:37,243,593...37,329,083
Ensembl chr12:38,134,574...38,214,036

SLC6A6

solute carrier family 6 member 6

involved_in

IEA

GO_REF:0000107

NCBI chr 3:14,323,251...14,411,949
Ensembl chr 3:14,663,955...14,752,326

SLC7A11

solute carrier family 7 member 11

acts_upstream_of_or_within

ISO

(PMID:25429150)

PMID:25429150

NCBI chr 4:130,529,677...130,601,396
Ensembl chr 4:141,849,343...141,959,849

STAT3

signal transducer and activator of transcription 3

involved_in

ISO

PMID:22284190

PMID:22284190

RGD:13702421

NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067

STAU1

staufen double-stranded RNA binding protein 1

involved_in

ISO

PMID:21635779

PMID:21635779

RGD:13792519

NCBI chr20:45,452,639...45,526,512
Ensembl chr20:46,517,772...46,578,024

STX3

syntaxin 3

involved_in

IEA

GO_REF:0000107

NCBI chr11:54,976,575...55,027,638
Ensembl chr11:58,426,894...58,476,417

SYNGAP1

synaptic Ras GTPase activating protein 1

involved_in

IEA

GO_REF:0000107

NCBI chr 6:32,999,408...33,033,067
Ensembl chr 6:34,110,652...34,144,490

SYNGR1

synaptogyrin 1

involved_in

IEA

GO_REF:0000107

NCBI chr22:20,253,936...20,289,470
Ensembl chr22:38,071,261...38,104,931

SYNPR

synaptoporin

involved_in

ISO

PMID:23312519

PMID:23312519

RGD:155230703

NCBI chr 3:63,186,196...63,523,267
Ensembl chr 3:64,569,397...64,908,183

synaptophysin

involved_in

IEA

GO_REF:0000107

NCBI chr X:41,487,538...41,500,039
Ensembl chr X:49,340,021...49,352,420

tenascin R

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:11377840)

PMID:11377840

GO_REF:0000107

NCBI chr 1:150,826,892...151,257,301
Ensembl chr 1:154,532,582...154,615,538

TRIO

trio Rho guanine nucleotide exchange factor

involved_in

ISO

PMID:26858404

PMID:26858404

RGD:155230791

NCBI chr 5:14,448,259...14,814,875
Ensembl chr 5:14,423,780...14,654,124

TRPC1

transient receptor potential cation channel subfamily C member 1

involved_in

ISO

PMID:31996247

PMID:31996247

RGD:405650334

NCBI chr 3:139,757,408...139,841,006
Ensembl chr 3:147,349,056...147,432,332

UBE2I

ubiquitin conjugating enzyme E2 I

involved_in

IEA

GO_REF:0000107

Ensembl chr16:1,367,288...1,382,575

UBE3A

ubiquitin protein ligase E3A

involved_in

ISO

(PMID:26166566)

PMID:26166566

NCBI chr15:4,494,029...4,595,415
Ensembl chr15:22,747,075...22,825,459

VGF

VGF nerve growth factor inducible

involved_in

ISO

PMID:14645472

PMID:14645472

RGD:2289061

NCBI chr 7:93,302,956...93,307,892

VPS35

VPS35 retromer complex component

involved_in

ISO

(PMID:30155515)

PMID:30155515

NCBI chr16:26,924,901...26,954,443
Ensembl chr16:45,817,371...45,846,531

WNK1

WNK lysine deficient protein kinase 1

involved_in

ISO

PMID:26126716

PMID:26126716

RGD:11053831

NCBI chr12:825,659...985,016
Ensembl chr12:791,153...944,602

WNT3A

Wnt family member 3A

involved_in

IEA

GO_REF:0000107

NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469

WNT5A

Wnt family member 5A

involved_in

ISO

PMID:26311509

PMID:26311509

RGD:11353570

NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051

modulation of excitatory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

amyloid beta precursor protein

involved_in

IEA

GO_REF:0000107

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

ERBB4

erb-b2 receptor tyrosine kinase 4

ISO

PMID:30206770

RGD:405650589

NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006

glutamate ionotropic receptor kainate type subunit 1

ISO

PMID:12597860

RGD:152995391

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

glutamate ionotropic receptor kainate type subunit 2

ISO

PMID:12597860

RGD:152995391

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

glutamate ionotropic receptor NMDA type subunit 2A

ISO

PMID:34233182

RGD:401940191

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

neuronal acetylcholine receptor subunit alpha-7

involved_in

ISO

(PMID:20974225)

PMID:20974225

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

PCLO

piccolo presynaptic cytomatrix protein

ISO

PMID:31074746

RGD:41408338

NCBI chr 7:74,714,364...75,126,518

SH3GL1

SH3 domain containing GRB2 like 1, endophilin A2

ISO

PMID:22750032

RGD:13463484

NCBI chr19:3,383,267...3,423,165
Ensembl chr19:4,329,750...4,340,121

SLC8A2

solute carrier family 8 member A2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:44,420,146...44,464,242
Ensembl chr19:53,077,857...53,113,830

SLC8A3

solute carrier family 8 member A3

acts_upstream_of_or_within

ISO

(PMID:29274751)

PMID:29274751

NCBI chr14:50,634,091...50,779,712

syntaxin 1A

involved_in

ISO

PMID:18703708

PMID:18703708

RGD:11535099

Ensembl chr 7:80,852,495...80,862,255

TMEM108

transmembrane protein 108

involved_in

IEA

GO_REF:0000107

NCBI chr 3:130,105,824...130,468,122
Ensembl chr 3:137,775,339...137,944,660

ZMYND8

zinc finger MYND-type containing 8

ISO

PMID:24117785

RGD:8554267

NCBI chr20:43,540,819...43,701,322
Ensembl chr20:44,624,487...44,772,032

modulation of inhibitory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cholinergic receptor nicotinic alpha 2 subunit

ISO

MMO:0000293

PMID:19385992

RGD:152995360

NCBI chr 8:26,729,767...26,749,277
Ensembl chr 8:23,932,846...23,952,377

DBN1

drebrin 1

ISO

PMID:19174472

RGD:10398809

NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872

dopamine receptor D4

ISO

PMID:12417643

RGD:401960856

NCBI chr11:640,401...646,775

negative regulation of acetylcholine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HTR6

5-hydroxytryptamine receptor 6

ISO

PMID:16987217

RGD:2317005

NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680

negative regulation of calcium ion-dependent exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cyclin dependent kinase 5

acts_upstream_of_or_within

ISO

PMID:23699505

PMID:23699505

RGD:13792535

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

negative regulation of dopamine uptake involved in synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synuclein alpha

involved_in

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

negative regulation of excitatory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBLN1

cerebellin 1 precursor

involved_in

IEA

GO_REF:0000107

NCBI chr16:29,538,723...29,542,625
Ensembl chr16:48,427,645...48,430,512

CELF4

CUGBP Elav-like family member 4

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr18:30,495,149...30,818,358
Ensembl chr18:34,068,123...34,374,372

glutamate metabotropic receptor 5

ISO

PMID:17389377

RGD:598099557

NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953

LOC100988043

eukaryotic initiation factor 4A-III

ISO

PMID:17632064

RGD:10044262

NCBI chr17:74,221,793...74,233,738

LOC100994646

neuroligin-4, Y-linked

involved_in

IEA

GO_REF:0000107

Ensembl chr X:5,756,699...6,018,008

leucine rich repeat kinase 2

involved_in

IEA

GO_REF:0000107

NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462

MTMR2

myotubularin related protein 2

involved_in

ISO

PMID:20410104

PMID:20410104

RGD:8553482

NCBI chr11:90,839,577...90,929,731
Ensembl chr11:94,367,038...94,457,138

neuroligin 3

involved_in

ISO

(PMID:21808020)

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

NLGN4X

neuroligin 4 X-linked

involved_in

IEA

GO_REF:0000107

Ensembl chr X:5,756,699...6,018,008

NPY2R

neuropeptide Y receptor Y2

ISO

PMID:12055128

RGD:1642608

NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231

polo like kinase 2

ISO

PMID:20802490

RGD:152995511

NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793

parkin RBR E3 ubiquitin protein ligase

ISO

PMID:19033459

RGD:10413844

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

phosphatase and tensin homolog

involved_in

ISO

(PMID:21411674)

PMID:21411674

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

S1PR2

sphingosine-1-phosphate receptor 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:9,771,888...9,781,944
Ensembl chr19:10,436,502...10,437,563

TMEM25

transmembrane protein 25

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr11:113,368,595...113,384,290
Ensembl chr11:117,299,183...117,314,494

negative regulation of long-term synaptic depression

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A1 receptor

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

advanced glycosylation end-product specific receptor

involved_in

IEA

GO_REF:0000107

NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641

fragile X messenger ribonucleoprotein 1

involved_in

ISO

(PMID:11438589)

PMID:11438589

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

NR3C1

nuclear receptor subfamily 3 group C member 1

ISO

PMID:19437411

RGD:408345242

NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269

negative regulation of long-term synaptic potentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

IEA

GO_REF:0000107

NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941

adenosine A1 receptor

ISO

PMID:14596853

RGD:1625717

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

advanced glycosylation end-product specific receptor

involved_in

IEA

GO_REF:0000107

NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641

APOE

apolipoprotein E

involved_in

IEA

GO_REF:0000107

NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490

amyloid beta precursor protein

involved_in

IEA

GO_REF:0000107

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

C23H22orf39

chromosome 23 C22orf39 homolog

involved_in

IEA

GO_REF:0000107

NCBI chr22:2,200,164...2,207,473
Ensembl chr22:17,875,330...17,882,694

CX3CR1

C-X3-C motif chemokine receptor 1

ISO

PMID:23855980

RGD:9491766

NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219

EPHA4

EPH receptor A4

involved_in

IEA

GO_REF:0000107

NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790

FAM107A

family with sequence similarity 107 member A

involved_in

ISO

(PMID:21969592)

PMID:21969592

NCBI chr 3:58,494,342...58,557,712
Ensembl chr 3:59,903,602...59,967,013

FMR1 autosomal homolog 1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:177,948,040...178,012,705

protein phosphatase 1 regulatory subunit 9A

ISO

PMID:16899074

RGD:10002752

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

PRNP

prion protein (Kanno blood group)

involved_in

ISO

PMID:21593310

PMID:21593310

RGD:12790639

NCBI chr20:4,713,616...4,728,847
Ensembl chr20:4,523,155...4,523,916

pleiotrophin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623

TYROBP

transmembrane immune signaling adaptor TYROBP

involved_in

IEA

GO_REF:0000107

NCBI chr19:32,821,279...32,825,488
Ensembl chr19:41,570,683...41,575,226

negative regulation of mini excitatory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SYNE1

spectrin repeat containing nuclear envelope protein 1

ISO

PMID:24191017

RGD:13209020

NCBI chr 6:149,936,306...150,454,822
Ensembl chr 6:154,627,904...155,144,076

negative regulation of neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASIC1

acid sensing ion channel subunit 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:38,672,253...38,698,247

GGCX

gamma-glutamyl carboxylase

involved_in

IEA

GO_REF:0000107

NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567

neurofibromin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

PNKD

PNKD metallo-beta-lactamase domain containing

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:105,529,775...105,606,207
Ensembl chr2B:224,127,504...224,204,046

SLC30A1

solute carrier family 30 member 1

involved_in

ISO

PMID:16741752

PMID:16741752

RGD:8554228

NCBI chr 1:187,139,544...187,147,113

synaptotagmin 4

involved_in

ISO

PMID:10397765

PMID:10397765

RGD:11535116

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

negative regulation of retrograde trans-synaptic signaling by neuropeptide

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 4

involved_in

ISO

(PMID:19448629)

SynGO-UCL

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

negative regulation of short-term neuronal synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 4

involved_in

ISO

(PMID:15390175)

PMID:15390175

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

negative regulation of short-term synaptic potentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PRRT2

proline rich transmembrane protein 2

involved_in

IEA

GO_REF:0000107

Ensembl chr16:30,183,352...30,187,862

negative regulation of spontaneous neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein phosphatase 1 regulatory subunit 9A

ISO

PMID:16899074

RGD:10002752

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

parkin RBR E3 ubiquitin protein ligase

involved_in

IEA

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

negative regulation of synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cyclin dependent kinase 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

GRID1

glutamate ionotropic receptor delta type subunit 1

involved_in

IEA

GO_REF:0000107

NCBI chr10:82,017,436...82,795,410
Ensembl chr10:85,586,147...86,353,410

NR3C1

nuclear receptor subfamily 3 group C member 1

ISO

PMID:22918985

RGD:7174737

NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269

RGS14

regulator of G protein signaling 14

involved_in

IEA

GO_REF:0000107

NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453

RIN1

Ras and Rab interactor 1

acts_upstream_of_or_within

ISO

(PMID:12574403)

PMID:12574403

NCBI chr11:61,697,751...61,702,501
Ensembl chr11:65,023,138...65,027,605

unc-13 homolog B

involved_in

ISO

(PMID:23658173)

PMID:23658173

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

unc-13 homolog C

involved_in

ISO

(PMID:23658173)

PMID:23658173

NCBI chr15:32,914,784...33,563,610

negative regulation of synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

involved_in

IEA

GO_REF:0000107

NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885

ADNP

activity dependent neuroprotector homeobox

ISO

PMID:15963648

RGD:2312778

NCBI chr20:47,233,696...47,276,075
Ensembl chr20:48,361,043...48,400,387

BCHE

butyrylcholinesterase

ISO

PMID:16275899

RGD:1599456

NCBI chr 3:162,794,184...162,858,574
Ensembl chr 3:170,845,494...170,911,481

dopamine receptor D1

ISO

PMID:17314300

RGD:1625010

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

dopamine receptor D2

ISO

PMID:17314300

RGD:1625010

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

dopamine receptor D4

ISO

PMID:17314300

RGD:1625010

NCBI chr11:640,401...646,775

GABBR1

gamma-aminobutyric acid type B receptor subunit 1

ISO

PMID:12604336

RGD:2315497

NCBI chr 6:29,405,026...29,437,108
Ensembl chr 6:30,065,119...30,095,304

GNAI1

G protein subunit alpha i1

ISO

PMID:11923410

RGD:625670

NCBI chr 7:72,102,937...72,188,124
Ensembl chr 7:85,812,249...85,851,283

GNAI2

G protein subunit alpha i2

ISO

PMID:11923410

RGD:625670

NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988

IL1B

interleukin 1 beta

involved_in

ISO

(PMID:20739563)

PMID:20739563

NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424

NPY2R

neuropeptide Y receptor Y2

ISO

PMID:15295007

RGD:1642503

NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231

PCDH17

protocadherin 17

acts_upstream_of_or_within

ISO

(PMID:23684785)

PMID:23684785

NCBI chr13:38,801,514...38,900,811
Ensembl chr13:57,532,850...57,631,725

RAPGEF4

Rap guanine nucleotide exchange factor 4

ISO

PMID:19734897

RGD:2314692

NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644

tenascin R

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:150,826,892...151,257,301
Ensembl chr 1:154,532,582...154,615,538

tumor protein p63 regulated 1 like

acts_upstream_of_or_within

ISO

(PMID:33431696)

PMID:33431696

NCBI chr 1:2,296,601...2,301,687

negative regulation of synaptic transmission, dopaminergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KCNQ4

potassium voltage-gated channel subfamily Q member 4

ISO

PMID:16775195

RGD:1600308

NCBI chr 1:40,076,552...40,133,913
Ensembl chr 1:41,396,111...41,452,780

PMCH

pro-melanin concentrating hormone

ISO

PMID:15555641

RGD:1642493

NCBI chr12:99,783,925...99,785,292
Ensembl chr12:103,181,497...103,182,616

PTGS2

prostaglandin-endoperoxide synthase 2

ISO

PMID:18764909

RGD:2300272

NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519

SLC6A4

solute carrier family 6 member 4

ISO

PMID:20730799

RGD:4889470

NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882

negative regulation of synaptic transmission, GABAergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A1 receptor

NOT

ISO

in immature hippocampal CA1 neurons
in postnatal 30 day hippocampal CA1 neurons

PMID:12626609

RGD:1625273

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

brain derived neurotrophic factor

acts_upstream_of_or_within

ISO

(PMID:16754670)

PMID:16754670

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

CNR2

cannabinoid receptor 2

ISO

PMID:19616018

RGD:2316192

NCBI chr 1:23,066,153...23,108,065
Ensembl chr 1:24,050,008...24,051,090

contactin associated protein 2

involved_in

ISO

(PMID:28966979)

PMID:28966979

NCBI chr 7:137,858,607...140,150,820
Ensembl chr 7:150,345,240...152,626,818

dopamine receptor D4

ISO

PMID:12417643

RGD:401960856

NCBI chr11:640,401...646,775

glutamate ionotropic receptor kainate type subunit 1

ISO

PMID:12533604

RGD:1642497

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

5-hydroxytryptamine receptor 1B

ISO

PMID:17229091

RGD:1626455

NCBI chr 6:75,309,078...75,313,747
Ensembl chr 6:78,596,408...78,597,580

NPY5R

neuropeptide Y receptor Y5

ISO

PMID:11796508

RGD:1625505

NCBI chr 4:155,603,739...155,612,302

SLC6A1

solute carrier family 6 member 1

ISO

PMID:17317750

RGD:1643193

NCBI chr 3:10,930,455...10,976,968
Ensembl chr 3:11,296,023...11,323,624

syntaxin binding protein 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

negative regulation of synaptic transmission, glutamatergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A1 receptor

ISO

K+-evoked glutamate release

PMID:16481441

RGD:1625231

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

ATAD1

ATPase family AAA domain containing 1

involved_in

ISO

(PMID:21496646)

PMID:21496646

NCBI chr10:84,473,087...84,544,902
Ensembl chr10:87,981,974...88,048,228

dopamine receptor D2

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

DRD3

dopamine receptor D3

involved_in

IEA

GO_REF:0000118

NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403

dopamine receptor D4

involved_in

IEA

GO_REF:0000118

NCBI chr11:640,401...646,775

glutamate ionotropic receptor kainate type subunit 1

acts_upstream_of_or_within

ISO

(PMID:11985817)

PMID:11985817 PMID:17395219

RGD:1642466

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within
involved_in

IEA
ISO

PMID:16420445

PMID:16420445

GO_REF:0000107 RGD:8554693

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

GRIK3

glutamate ionotropic receptor kainate type subunit 3

involved_in

ISO

PMID:16420445

PMID:16420445

RGD:8554693

NCBI chr 1:36,060,594...36,312,781
Ensembl chr 1:37,415,254...37,651,705

5-hydroxytryptamine receptor 1B

ISO

PMID:17392733

RGD:1626454

NCBI chr 6:75,309,078...75,313,747
Ensembl chr 6:78,596,408...78,597,580

HTR2A

5-hydroxytryptamine receptor 2A

ISO

PMID:17016851

RGD:1624386

NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826

MYO5A

myosin VA

ISO

PMID:27771352

RGD:41412185

NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319

NPY2R

neuropeptide Y receptor Y2

ISO

PMID:16190896

RGD:1642508

NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231

PLA2G6

phospholipase A2 group VI

ISO

PMID:15132431

RGD:6482754

NCBI chr22:18,998,060...19,094,507
Ensembl chr22:36,849,794...36,919,509
Ensembl chr22:36,849,794...36,919,509

parkin RBR E3 ubiquitin protein ligase

ISO

PMID:19033459

RGD:10413844

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

negative regulation of synaptic vesicle exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B-Raf proto-oncogene, serine/threonine kinase

acts_upstream_of_or_within

ISO

(PMID:23616533)

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

fragile X messenger ribonucleoprotein 1

involved_in

ISO

PMID:24709664

PMID:24709664

RGD:11059581

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

RAP1A

RAP1A, member of RAS oncogene family

acts_upstream_of_or_within

ISO

(PMID:23616533)

NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813

RAP1B

RAP1B, member of RAS oncogene family

acts_upstream_of_or_within

ISO

(PMID:23616533)

NCBI chr12:66,122,212...66,172,450
Ensembl chr12:68,942,053...68,955,649

synaptotagmin 4

involved_in

ISO

(PMID:19448629)

SynGO-UCL

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

neuromuscular synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADARB1

adenosine deaminase RNA specific B1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr21:31,374,841...31,532,721
Ensembl chr21:44,715,931...44,815,748

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

ISO

(PMID:10686170)

PMID:10686170

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

CHAT

choline O-acetyltransferase

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:12441053)

PMID:12441053

GO_REF:0000118

NCBI chr10:44,574,925...44,629,618

CHRM1

cholinergic receptor muscarinic 1

ISO

PMID:12534975

RGD:724727

NCBI chr11:58,261,476...58,274,685
Ensembl chr11:61,614,818...61,616,200

CHRNA1

cholinergic receptor nicotinic alpha 1 subunit

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:62,022,498...62,039,370
Ensembl chr2B:179,476,677...179,504,763

CHRNB1

cholinergic receptor nicotinic beta 1 subunit

involved_in

IEA

GO_REF:0000107

NCBI chr17:7,479,056...7,490,314
Ensembl chr17:7,465,229...7,476,099

EGR3

early growth response 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 8:21,937,516...21,943,646
Ensembl chr 8:18,877,396...18,882,874

ELKS/RAB6-interacting/CAST family member 1

involved_in

IEA

GO_REF:0000118

NCBI chr12:1,066,034...1,597,562
Ensembl chr12:1,027,967...1,545,431

ELKS/RAB6-interacting/CAST family member 2

involved_in

IEA

GO_REF:0000118

NCBI chr 3:55,438,875...56,417,072
Ensembl chr 3:56,836,941...57,599,248

ETV5

ETS variant transcription factor 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:183,076,677...183,139,886
Ensembl chr 3:191,545,915...191,606,550

FCHSD2

FCH and double SH3 domains 2

involved_in

IEA

GO_REF:0000118

NCBI chr11:67,915,796...68,219,482

KIF1B

kinesin family member 1B

involved_in

ISO

(PMID:11389829)

PMID:11389829

NCBI chr 1:8,969,910...9,141,964
Ensembl chr 1:10,198,997...10,364,577
Ensembl chr 1:10,198,997...10,364,577

LARGE xylosyl- and glucuronyltransferase 1

acts_upstream_of_or_within

ISO

(PMID:23222475)

PMID:23222475

NCBI chr22:14,077,463...14,929,250

LOC100982539

signal transducer CD24

acts_upstream_of_or_within

ISO

(PMID:16606832)

PMID:16606832

NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847

MYLK2

myosin light chain kinase 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508

NTF3

neurotrophin 3

acts_upstream_of_or_within

ISO

(PMID:11978828)

PMID:11978828

NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989

purinergic receptor P2X 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:129,969,793...129,974,399

purinergic receptor P2X 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:52,579,190...52,614,329
Ensembl chr 3:160,070,875...160,106,120

RAB3A, member RAS oncogene family

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

RIMBP2

RIMS binding protein 2

involved_in

IEA

GO_REF:0000118

NCBI chr12:128,009,575...128,338,009
Ensembl chr12:132,225,056...132,305,103

SLC5A7

solute carrier family 5 member 7

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:15173594)

PMID:15173594

GO_REF:0000118

NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860

STAC3

SH3 and cysteine rich domain 3

involved_in

IEA

GO_REF:0000107

NCBI chr12:31,674,537...31,683,917
Ensembl chr12:31,928,955...31,936,251

syntaxin binding protein 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

VPS54

VPS54 subunit of GARP complex

involved_in

IEA

GO_REF:0000107

NCBI chr2A:63,959,930...64,087,102
Ensembl chr2A:65,086,374...65,176,634

neuron-neuron synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARID1B

AT-rich interaction domain 1B

acts_upstream_of_or_within

ISO

(PMID:26937011)

PMID:26937011

NCBI chr 6:154,581,148...155,018,706

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

ISO

(PMID:16540584)

PMID:16540584

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

CAMK4

calcium/calmodulin dependent protein kinase IV

acts_upstream_of_or_within

ISO

(PMID:10964952)

PMID:10964952

NCBI chr 5:106,590,803...106,855,592
Ensembl chr 5:112,393,211...112,647,203

dopamine receptor D2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

KIF1B

kinesin family member 1B

involved_in

ISO

(PMID:11389829)

PMID:11389829

NCBI chr 1:8,969,910...9,141,964
Ensembl chr 1:10,198,997...10,364,577
Ensembl chr 1:10,198,997...10,364,577

OPRL1

opioid related nociceptin receptor 1

involved_in

IEA

GO_REF:0000107

Ensembl chr20:62,004,176...62,017,866

PNOC

prepronociceptin

involved_in

IEA

GO_REF:0000107

NCBI chr 8:27,596,413...27,622,844
Ensembl chr 8:24,796,638...24,822,758

phosphatase and tensin homolog

involved_in

ISO

(PMID:18082964)

PMID:18082964

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

TMOD2

tropomodulin 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr15:30,690,641...30,757,960
Ensembl chr15:49,035,929...49,079,570

VDAC1

voltage dependent anion channel 1

acts_upstream_of_or_within

ISO

(PMID:11907043)

NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005

VDAC3

voltage dependent anion channel 3

acts_upstream_of_or_within

ISO

(PMID:11907043)

NCBI chr 8:41,638,522...41,652,637
Ensembl chr 8:39,082,698...39,097,437

neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASIC1

acid sensing ion channel subunit 1

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr12:38,672,253...38,698,247

BRSK1

BR serine/threonine kinase 1

involved_in

ISO

PMID:16630837

PMID:16630837

RGD:8553864

NCBI chr19:52,326,538...52,355,060
Ensembl chr19:61,021,493...61,045,659

calcium voltage-gated channel subunit alpha1 B

acts_upstream_of_or_within

ISO

(PMID:12827191)

NCBI chr 9:108,989,621...109,256,841

diacylglycerol kinase iota

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310

dishevelled segment polarity protein 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008

LIN7A

lin-7 homolog A, crumbs cell polarity complex component

involved_in
acts_upstream_of_or_within

IEA

UniProt
Ensembl

GO_REF:0000104 GO_REF:0000107

NCBI chr12:78,312,501...78,456,871
Ensembl chr12:81,442,152...81,567,522

LIN7B

lin-7 homolog B, crumbs cell polarity complex component

involved_in
acts_upstream_of_or_within

IEA

UniProt
Ensembl

GO_REF:0000104 GO_REF:0000107

NCBI chr19:46,125,272...46,129,450
Ensembl chr19:55,047,704...55,055,761

LIN7C

lin-7 homolog C, crumbs cell polarity complex component

involved_in
acts_upstream_of_or_within

IEA

UniProt
Ensembl

GO_REF:0000104 GO_REF:0000107

NCBI chr11:27,458,735...27,471,068
Ensembl chr11:27,361,301...27,373,440

neurofibromin 1

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

neurexin 1

acts_upstream_of_or_within

ISO

(PMID:12827191)

NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277

neurexin 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:59,959,917...60,078,093
Ensembl chr11:63,303,659...63,409,687

neurexin 3

acts_upstream_of_or_within

ISO

(PMID:12827191)

NCBI chr14:58,729,335...60,444,769
Ensembl chr14:78,002,036...79,619,696

PTPRF interacting protein alpha 3

ISO

PMID:11797009

RGD:633666

NCBI chr19:46,130,396...46,162,065
Ensembl chr19:55,056,824...55,089,124

PPT1

palmitoyl-protein thioesterase 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609

PTPRN2

protein tyrosine phosphatase receptor type N2

involved_in

IEA

GO_REF:0000107

NCBI chr 7:149,158,513...150,390,077
Ensembl chr 7:160,851,703...161,756,325

regulating synaptic membrane exocytosis 1

acts_upstream_of_or_within

ISO

(PMID:25730884)

PMID:25730884

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within

ISO

(PMID:25730884)

PMID:25730884

NCBI chr 8:100,156,403...100,894,128

synaptosome associated protein 25

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SNAP91

synaptosome associated protein 91

involved_in

ISO

(PMID:11102472)

PMID:11102472

NCBI chr 6:81,441,792...81,600,505
Ensembl chr 6:84,720,850...84,874,407

synuclein alpha

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

syntaxin binding protein 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

SYN1

synapsin I

acts_upstream_of_or_within

ISO

(PMID:7777057)

InterPro
Ensembl
TreeGrafter

PMID:7777057

NCBI chr X:40,007,777...40,055,801

SYN2

synapsin II

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000002 GO_REF:0000107 GO_REF:0000118

NCBI chr 3:11,935,680...12,118,981
Ensembl chr 3:12,282,573...12,464,413

SYN3

synapsin III

involved_in

IEA

GO_REF:0000002 GO_REF:0000118

NCBI chr22:13,517,932...14,069,661
Ensembl chr22:31,373,604...31,866,798

synaptotagmin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

synaptotagmin 4

acts_upstream_of_or_within

ISO

(PMID:15197251)

PMID:15197251

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

unc-13 homolog A

acts_upstream_of

ISO

(PMID:11792326)

PMID:7559667 PMID:11792326

RGD:634400

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

WNT7A

Wnt family member 7A

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386

neurotransmitter secretion involved in regulation of skeletal muscle contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NR4A1

nuclear receptor subfamily 4 group A member 1

ISO

PMID:29530712

RGD:40924655

NCBI chr12:36,703,903...36,740,211
Ensembl chr12:37,480,300...37,501,188

positive regulation of acetylcholine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A2a receptor

ISO

phrenic nerve terminals in the presence of adenosine transport inhibitor deoxycoformycin

PMID:12679375

RGD:1625693

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

HTR2C

5-hydroxytryptamine receptor 2C

ISO

PMID:15266551

RGD:1625007

NCBI chr X:103,673,172...103,999,133
Ensembl chr X:114,199,485...114,503,201

SLC18A3

solute carrier family 18 member A3

involved_in

ISO

(PMID:19635813)

PMID:19635813

NCBI chr10:44,630,006...44,632,419

TACR2

tachykinin receptor 2

ISO

PMID:12747940

RGD:5147477

NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224

positive regulation of calcium ion-dependent exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

calcium voltage-gated channel subunit alpha1 B

involved_in

ISO

PMID:23699505

PMID:23699505

RGD:13792535

NCBI chr 9:108,989,621...109,256,841

protein phosphatase 3 catalytic subunit alpha

acts_upstream_of_or_within

ISO

PMID:23699505

PMID:23699505

RGD:13792535

NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394

synaptotagmin 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

positive regulation of dopamine uptake involved in synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

dopamine receptor D2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

NAT8L

N-acetyltransferase 8 like

involved_in

ISO

(PMID:19014384)

PMID:19014384

NCBI chr 4:2,201,326...2,211,302

RAB3B

RAB3B, member RAS oncogene family

involved_in

IEA

GO_REF:0000107

NCBI chr 1:51,170,956...51,242,828
Ensembl chr 1:52,666,713...52,723,975

positive regulation of excitatory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

amyloid beta precursor protein

involved_in

ISO

(PMID:19118188)

PMID:19118188

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

BAIAP2

BAR/IMD domain containing adaptor protein 2

ISO

PMID:15758177

RGD:9684984

NCBI chr17:75,460,491...75,542,700
Ensembl chr17:81,187,021...81,269,714

CACNB3

calcium voltage-gated channel auxiliary subunit beta 3

ISO

PMID:22187436

RGD:13514092

NCBI chr12:39,918,022...39,931,386
Ensembl chr12:40,797,293...40,811,409

CUX2

cut like homeobox 2

involved_in

IEA

GO_REF:0000107

NCBI chr12:108,600,286...108,975,588
Ensembl chr12:112,175,555...112,311,221

DBN1

drebrin 1

ISO

PMID:19174472

RGD:10398809

NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872

discs large MAGUK scaffold protein 4

involved_in

ISO

PMID:12930820

NCBI chr17:7,219,911...7,247,509
Ensembl chr17:7,207,483...7,235,985

dopamine receptor D4

ISO

PMID:21622557

RGD:7248611

NCBI chr11:640,401...646,775

dishevelled segment polarity protein 1

involved_in

ISO

PMID:21670302

PMID:21670302

RGD:10449514

NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008

glutamate ionotropic receptor AMPA type subunit 1

ISO

PMID:23345231

RGD:405100730

NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660

PMID:12930820 PMID:19793963 PMID:22246434

glutamate ionotropic receptor NMDA type subunit 1

involved_in

ISO

PMID:12930820
PMID:22246434
PMID:19793963

BHF-UCL
ComplexPortal

RGD:150521639 RGD:150521643 RGD:8554754

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

BHF-UCL
RGD
ComplexPortal

glutamate ionotropic receptor NMDA type subunit 2A

involved_in

ISO

PMID:12930820
PMID:22246434

PMID:12930820 PMID:22246434 PMID:29339324

RGD:150521639 RGD:401940161 RGD:8554754

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

PMID:19793963 PMID:29339324

glutamate ionotropic receptor NMDA type subunit 2B

involved_in

ISO

PMID:19793963

ComplexPortal
RGD

RGD:150521643 RGD:401940161

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

glutamate ionotropic receptor NMDA type subunit 2C

involved_in

ISO

PMID:19793963

NCBI chr17:68,787,670...68,807,192

glutamate ionotropic receptor NMDA type subunit 2D

involved_in

ISO

PMID:19793963

NCBI chr19:45,392,258...45,447,004

GRIP2

glutamate receptor interacting protein 2

involved_in

ISO

PMID:20083202

PMID:20083202

RGD:4107359

NCBI chr 3:14,411,825...14,525,388
Ensembl chr 3:14,756,638...14,804,952

GRK2

G protein-coupled receptor kinase 2

ISO

PMID:28975565

RGD:13506836

NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066

glycogen synthase kinase 3 beta

ISO

PMID:20007479

RGD:4107027

NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771

neuronal acetylcholine receptor subunit alpha-7

involved_in

ISO

(PMID:19118188)

PMID:19118188

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

NETO1

neuropilin and tolloid like 1

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr18:66,114,425...66,240,141
Ensembl chr18:69,408,116...69,527,333

NETO2

neuropilin and tolloid like 2

NOT|acts_upstream_of_or_within

ISO

(PMID:21734292)

PMID:21734292

NCBI chr16:27,343,333...27,405,173
Ensembl chr16:46,235,165...46,284,344

nerve growth factor receptor

ISO

PMID:23114219

RGD:10414080

NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966

neuroligin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

neuroligin 2

involved_in

ISO

(PMID:15620359)

PMID:15620359

NCBI chr17:7,438,853...7,454,014

neuroligin 3

involved_in

ISO

(PMID:21642956)

PMID:21642956

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

neurexin 1

involved_in

ISO

(PMID:19098102)
(PMID:19822762)

PMID:19098102 PMID:19822762

NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277

neurotrophic receptor tyrosine kinase 2

ISO

PMID:31329835

RGD:597015744

NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678

PRKAR1B

protein kinase cAMP-dependent type I regulatory subunit beta

ISO

PMID:33479380

RGD:150519900

NCBI chr 7:700,691...876,497
Ensembl chr 7:923,668...1,097,456

PRKCZ

protein kinase C zeta

involved_in

ISO

PMID:11914719

PMID:11914719

RGD:8554098

NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855

phosphatase and tensin homolog

involved_in

ISO

(PMID:18082964)

PMID:18082964

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

protein tyrosine kinase 2 beta

involved_in

ISO

PMID:11239437

PMID:11239437

RGD:8553497

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

reelin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037

RGS4

regulator of G protein signaling 4

ISO

PMID:17220354

RGD:13524537

NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225

regulating synaptic membrane exocytosis 1

involved_in

ISO

(PMID:21262469)

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

ISO

(PMID:21262469)

NCBI chr 8:100,156,403...100,894,128

SHANK1

SH3 and multiple ankyrin repeat domains 1

involved_in

IEA

GO_REF:0000107

NCBI chr19:47,623,474...47,684,476
Ensembl chr19:56,526,577...56,580,442

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21167025), (PMID:21423165), (PMID:21795692)

PMID:21167025 PMID:21423165 PMID:21795692

NCBI chr22:30,951,866...30,973,608

SSH1

slingshot protein phosphatase 1

ISO

PMID:20442266

RGD:11535133

NCBI chr12:106,357,147...106,432,295
Ensembl chr12:109,758,399...109,823,444

syntaxin 1A

involved_in

IEA

GO_REF:0000107

Ensembl chr 7:80,852,495...80,862,255

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

TBC1D24

TBC1 domain family member 24

ISO

PMID:24469796

RGD:11537391

NCBI chr16:1,331,630...1,362,320
Ensembl chr16:2,581,835...2,603,912

TRPV1

transient receptor potential cation channel subfamily V member 1

ISO

PMID:30676422

RGD:597976449

NCBI chr17:3,612,781...3,658,608
Ensembl chr17:3,609,952...3,637,579

WNT7A

Wnt family member 7A

involved_in

IEA

GO_REF:0000107

NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386

positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DTNBP1

dystrobrevin binding protein 1

ISO

PMID:15345706

RGD:11251758

NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256

RAB3 GTPase activating protein catalytic subunit 1

involved_in

ISO

(PMID:16782817)

NCBI chr2B:24,692,363...24,810,685
Ensembl chr2B:139,125,375...139,242,721

positive regulation of glutamate secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KMO

kynurenine 3-monooxygenase

ISO

PMID:15829251

RGD:13513901

NCBI chr 1:217,094,037...217,157,827
Ensembl chr 1:222,075,268...222,138,866

syntaxin binding protein 1

ISO

PMID:16951547

RGD:12904030

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

positive regulation of inhibitory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABAT

4-aminobutyrate aminotransferase

ISO

PMID:11495935

RGD:10047060

NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420

glutamate ionotropic receptor NMDA type subunit 2A

ISO

PMID:29339324

RGD:401940161

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

glutamate ionotropic receptor NMDA type subunit 2B

ISO

PMID:29339324

RGD:401940161

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

IGSF9B

immunoglobulin superfamily member 9B

acts_upstream_of_or_within

ISO

(PMID:23751499)

PMID:23751499

NCBI chr11:128,734,144...128,802,383
Ensembl chr11:132,615,398...132,664,811

neuroligin 2

involved_in

ISO

PMID:18550748
(PMID:15620359), (PMID:17582332)

PMID:15620359 PMID:17582332 PMID:18550748

RGD:8554527

NCBI chr17:7,438,853...7,454,014

neuroligin 3

ISO

PMID:19406211

RGD:8554851

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

NTSR1

neurotensin receptor 1

ISO

PMID:15664687

RGD:9831120

NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056

regulating synaptic membrane exocytosis 1

involved_in

ISO

PMID:21262469
(PMID:21262469)

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

ISO

(PMID:21262469)

NCBI chr 8:100,156,403...100,894,128

unc-13 homolog B

involved_in

ISO

PMID:21262469

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

positive regulation of long-term neuronal synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

brain derived neurotrophic factor

ISO

PMID:14699417

RGD:4891114

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

EPH receptor B2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118

fragile X messenger ribonucleoprotein 1

involved_in

ISO
IEA

GO_REF:0000118 RGD:38501107

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

FMR1 autosomal homolog 1

involved_in

IEA

GO_REF:0000118

NCBI chr 3:177,948,040...178,012,705

FXR2

FMR1 autosomal homolog 2

involved_in

IEA

GO_REF:0000118

NCBI chr17:7,622,855...7,646,340
Ensembl chr17:7,609,736...7,631,758

glutamate metabotropic receptor 5

ISO

PMID:12740378

RGD:731147

NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953

KDR

kinase insert domain receptor

ISO

PMID:18221855

RGD:2292019

NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109

KIT

KIT proto-oncogene, receptor tyrosine kinase

ISO

PMID:11112797

RGD:2292520

NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473

NEURL1

neuralized E3 ubiquitin protein ligase 1

involved_in

ISO

(PMID:22153079)

PMID:22153079

NCBI chr10:100,093,614...100,192,485

neuroplastin

involved_in

ISO

PMID:10759566

HGNC-UCL

PMID:10759566

RGD:8553916

NCBI chr15:52,470,545...52,544,046
Ensembl chr15:71,229,992...71,269,579

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21167025)

PMID:21167025

NCBI chr22:30,951,866...30,973,608

positive regulation of long-term synaptic depression

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenylate cyclase 8

involved_in

IEA

GO_REF:0000107

NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073

CBLN1

cerebellin 1 precursor

involved_in

IEA

GO_REF:0000107

NCBI chr16:29,538,723...29,542,625
Ensembl chr16:48,427,645...48,430,512

fragile X messenger ribonucleoprotein 1

ISO

RGD:38501107

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

GRID2

glutamate ionotropic receptor delta type subunit 2

involved_in

IEA

GO_REF:0000107

NCBI chr 4:84,663,030...86,170,778
Ensembl chr 4:95,339,460...96,807,748

IQSEC2

IQ motif and Sec7 domain ArfGEF 2

ISO

PMID:27009485

RGD:11049506

NCBI chr X:45,447,977...45,535,836
Ensembl chr X:53,557,563...53,644,737

KCNB1

potassium voltage-gated channel subfamily B member 1

involved_in

IEA

GO_REF:0000107

NCBI chr20:45,636,371...45,821,536
Ensembl chr20:46,776,274...46,885,521

LOC100991256

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

ISO

(PMID:24052308)

PMID:24052308

NCBI chr19:51,148,567...51,154,764

MAPT

microtubule associated protein tau

ISO

PMID:24298146

RGD:10412705

NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129

neurotrophic receptor tyrosine kinase 2

ISO

PMID:31329835

RGD:597015744

NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678

protein phosphatase 1 regulatory subunit 9A

ISO

PMID:16899074

RGD:10002752

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

STAU2

staufen double-stranded RNA binding protein 2

ISO

PMID:21508097

RGD:10043164

NCBI chr 8:69,958,735...70,283,591
Ensembl chr 8:71,606,583...71,929,167

positive regulation of long-term synaptic potentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY1

adenylate cyclase 1

involved_in

IEA

GO_REF:0000107

NCBI chr 7:46,289,042...46,436,839
Ensembl chr 7:46,354,640...46,492,549

adenylate cyclase 8

involved_in

IEA

GO_REF:0000107

NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073

adenosine A2a receptor

ISO

PMID:14596853

RGD:1625717

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

ADRB1

adrenoceptor beta 1

ISO

PMID:21848869

RGD:8693685

NCBI chr10:110,642,491...110,646,595

AKAP5

A-kinase anchoring protein 5

involved_in

IEA

GO_REF:0000107

NCBI chr14:45,045,476...45,050,946
Ensembl chr14:63,302,200...63,303,483

amyloid beta precursor protein

involved_in

IEA

GO_REF:0000107

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

CPEB3

cytoplasmic polyadenylation element binding protein 3

involved_in

ISO

(PMID:26074003)

PMID:26074003

NCBI chr10:88,794,186...89,038,808
Ensembl chr10:92,320,240...92,506,089

CREB1

cAMP responsive element binding protein 1

ISO

PMID:16000619

RGD:10059422

NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130

CRTC1

CREB regulated transcription coactivator 1

ISO

PMID:17183642

RGD:9685167

NCBI chr19:18,123,375...18,221,832
Ensembl chr19:19,131,484...19,228,980

dopamine receptor D1

ISO

PMID:20377617

RGD:6907453

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

dopamine receptor D2

ISO

PMID:20377617

RGD:6907453

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

EIF2AK4

eukaryotic translation initiation factor 2 alpha kinase 4

involved_in

ISO

(PMID:16121183)

PMID:16121183

NCBI chr15:18,871,867...18,973,380
Ensembl chr15:37,120,044...37,229,211

EPH receptor B2

involved_in

IEA

GO_REF:0000107

NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118

fragile X messenger ribonucleoprotein 1

ISO

RGD:38501107

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

HNRNPK

heterogeneous nuclear ribonucleoprotein K

ISO

PMID:24990929

RGD:10002784

NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756

immunoglobulin superfamily member 11

involved_in

IEA

GO_REF:0000107

NCBI chr 3:116,033,187...116,153,134
Ensembl chr 3:122,948,246...122,972,742

LGMN

legumain

involved_in

ISO

(PMID:25326800)

PMID:25326800

NCBI chr14:73,337,607...73,383,462
Ensembl chr14:92,677,608...92,723,051

neuronal acetylcholine receptor subunit alpha-7

involved_in

ISO

(PMID:19118188)
(PMID:20974225)

PMID:19118188 PMID:20974225

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

MME

membrane metalloendopeptidase

involved_in

ISO

(PMID:16636059)

PMID:16636059

NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119

NOS1

nitric oxide synthase 1

ISO

PMID:23579428

RGD:7257653

NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005

neuroplastin

ISO

PMID:10759566

RGD:8553916

NCBI chr15:52,470,545...52,544,046
Ensembl chr15:71,229,992...71,269,579

NRGN

neurogranin

ISO

PMID:7620629

RGD:9835395

NCBI chr11:119,566,934...119,574,248

PDE9A

phosphodiesterase 9A

ISO

PMID:31578258

RGD:243048433

NCBI chr21:28,963,181...29,088,395
Ensembl chr21:42,275,697...42,398,681

PRKAR1B

protein kinase cAMP-dependent type I regulatory subunit beta

ISO

PMID:33479380

RGD:150519900

NCBI chr 7:700,691...876,497
Ensembl chr 7:923,668...1,097,456

PTPN5

protein tyrosine phosphatase non-receptor type 5

ISO

PMID:19026408

RGD:9835020

NCBI chr11:18,758,285...18,822,845
Ensembl chr11:18,673,366...18,711,885

reelin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21167025)

PMID:21167025

NCBI chr22:30,951,866...30,973,608

SHISA7

shisa family member 7

involved_in

ISO

(PMID:29199957)

PMID:29199957

NCBI chr19:52,475,852...52,496,819

SLC18A3

solute carrier family 18 member A3

involved_in

ISO

(PMID:23045697)

PMID:23045697

NCBI chr10:44,630,006...44,632,419

SQSTM1

sequestosome 1

involved_in

IEA

GO_REF:0000107

NCBI chr 5:174,960,727...174,989,946
Ensembl chr 5:182,284,436...182,299,093

STAU1

staufen double-stranded RNA binding protein 1

ISO

PMID:21508097

RGD:10043164

NCBI chr20:45,452,639...45,526,512
Ensembl chr20:46,517,772...46,578,024

ZDHHC2

zDHHC palmitoyltransferase 2

involved_in

ISO

PMID:25589740

PMID:25589740

RGD:21201275

NCBI chr 8:16,368,954...16,437,623
Ensembl chr 8:13,343,011...13,380,803

positive regulation of mini excitatory postsynaptic potential

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adrenoceptor beta 2

involved_in

IEA

GO_REF:0000107

NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892

AFDN

afadin, adherens junction formation factor

ISO

PMID:22948147

RGD:13838731

NCBI chr 6:165,778,026...165,923,685
Ensembl chr 6:170,775,904...170,882,784

immunoglobulin superfamily member 11

involved_in

ISO

PMID:26595655

PMID:26595655

RGD:11085699

NCBI chr 3:116,033,187...116,153,134
Ensembl chr 3:122,948,246...122,972,742

positive regulation of neuromuscular synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAPSN

receptor associated protein of the synapse

involved_in

ISO
IEA

PMID:19344765

GO_REF:0000118 RGD:8549750

NCBI chr11:47,387,324...47,398,579
Ensembl chr11:47,940,530...47,951,667

positive regulation of neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BAIAP3

BAI1 associated protein 3

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

Ensembl chr16:1,390,160...1,403,978

BGLAP

bone gamma-carboxyglutamate protein

involved_in
acts_upstream_of_or_within

ISO

(PMID:24074871)
(PMID:28851741)

PMID:24074871 PMID:28851741

NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432

calcium voltage-gated channel subunit alpha1 B

ISO

PMID:15987667

RGD:1626316

NCBI chr 9:108,989,621...109,256,841

DTNBP1

dystrobrevin binding protein 1

involved_in

IEA

GO_REF:0000107

NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256

GPR158

G protein-coupled receptor 158

involved_in

IEA

GO_REF:0000107

NCBI chr10:25,352,131...25,777,652
Ensembl chr10:25,722,127...26,140,997

MICU3

mitochondrial calcium uptake family member 3

acts_upstream_of_positive_effect

ISO

PMID:31862210

PMID:31862210

RGD:405650270

NCBI chr 8:16,240,845...16,335,601
Ensembl chr 8:13,186,498...13,277,247

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

SPHK1

sphingosine kinase 1

ISO

PMID:17325039

RGD:2311366

NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481

syntaxin 1A

involved_in

ISO
IEA

PMID:12183029

GO_REF:0000107 RGD:1581173

Ensembl chr 7:80,852,495...80,862,255

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

unc-13 homolog A

acts_upstream_of_or_within

ISO

(PMID:11792326)

PMID:11792326

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

positive regulation of spontaneous neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

positive regulation of substance P secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PTGER4

prostaglandin E receptor 4

ISO

PMID:15292051

RGD:10003094

NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148

positive regulation of synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenylate cyclase 8

involved_in

IEA

GO_REF:0000107

NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073

ANAPC2

anaphase promoting complex subunit 2

involved_in

IEA

GO_REF:0000107

NCBI chr 9:108,234,949...108,248,227
Ensembl chr 9:137,204,356...137,217,652

CDC20

cell division cycle 20

involved_in

IEA

GO_REF:0000107

NCBI chr 1:42,660,338...42,664,618
Ensembl chr 1:44,039,971...44,044,497

CFL1

cofilin 1

ISO

PMID:25723479

RGD:11570400

NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806

complexin 2

involved_in

IEA

GO_REF:0000107

NCBI chr 5:171,144,671...171,233,028
Ensembl chr 5:178,115,947...178,128,595

DBN1

drebrin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872

EPH receptor B2

involved_in

IEA

GO_REF:0000107

NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118

methyl-CpG binding protein 2

ISO

PMID:23015442

RGD:12790708

NCBI chr X:143,571,864...143,647,192
Ensembl chr X:153,465,204...153,527,854

MMP9

matrix metallopeptidase 9

ISO

PMID:17493927

RGD:1642034

NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129

NEUROD2

neuronal differentiation 2

involved_in

ISO

(PMID:19900895)

PMID:19900895

NCBI chr17:17,680,415...17,685,053

PTGS2

prostaglandin-endoperoxide synthase 2

ISO

PMID:18540883

RGD:2300227

NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519

SSH1

slingshot protein phosphatase 1

ISO

PMID:20442266

RGD:11535133

NCBI chr12:106,357,147...106,432,295
Ensembl chr12:109,758,399...109,823,444

unc-13 homolog A

involved_in

ISO

(PMID:23658173)

PMID:23658173

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

positive regulation of synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCKBR

cholecystokinin B receptor

ISO

PMID:19386755

RGD:2311324

NCBI chr11:6,393,435...6,405,821
Ensembl chr11:6,075,816...6,088,145

CCL2

C-C motif chemokine ligand 2

ISO

PMID:18584881

RGD:2303073

NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384

CLSTN1

calsyntenin 1

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:8,495,571...8,591,613
Ensembl chr 1:9,724,743...9,774,760

CLSTN2

calsyntenin 2

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 3:136,971,615...137,612,365
Ensembl chr 3:144,571,706...145,199,768

CLSTN3

calsyntenin 3

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr12:7,260,361...7,288,903
Ensembl chr12:7,175,951...7,204,526

discs large MAGUK scaffold protein 4

involved_in

ISO

PMID:12930820

NCBI chr17:7,219,911...7,247,509
Ensembl chr17:7,207,483...7,235,985

EFNB3

ephrin B3

ISO

PMID:17626212

RGD:152995392

NCBI chr17:7,737,297...7,743,732
Ensembl chr17:7,724,983...7,731,270

fragile X messenger ribonucleoprotein 1

ISO

RGD:38501107

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

GIP

gastric inhibitory polypeptide

ISO

PMID:18234983

RGD:2312531

NCBI chr17:8,573,104...8,580,424

glutamate ionotropic receptor AMPA type subunit 1

involved_in

ISO

PMID:11348590

PMID:11348590

RGD:8553683

NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660

glutamate ionotropic receptor AMPA type subunit 2

involved_in

ISO

PMID:11348590

PMID:11348590

RGD:8553683

NCBI chr 4:149,566,563...149,712,135
Ensembl chr 4:161,380,933...161,524,376

glutamate ionotropic receptor kainate type subunit 2

involved_in

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

glutamate ionotropic receptor NMDA type subunit 2B

ISO

PMID:19208366

RGD:2326032

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

HNRNPK

heterogeneous nuclear ribonucleoprotein K

ISO

PMID:24990929

RGD:10002784

NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756

KCTD13

potassium channel tetramerization domain containing 13

involved_in

IEA

GO_REF:0000107

KISS1

KiSS-1 metastasis suppressor

ISO

KISS1 receptor

ISO

PMID:16222076

RGD:1599289

NCBI chr19:211,563...215,332

LGI1

leucine rich glioma inactivated 1

involved_in

ISO

PMID:16990550

PMID:16990550

RGD:8553375

NCBI chr10:90,506,131...90,546,582
Ensembl chr10:94,016,703...94,056,820

NMU

neuromedin U

involved_in

ISO
IEA

PMID:15297576

GO_REF:0000118 RGD:1642123

NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965

OXT

oxytocin/neurophysin I prepropeptide

ISO

PMID:17314286

RGD:2304169

NCBI chr20:3,157,246...3,159,013

PRKCZ

protein kinase C zeta

ISO

maintenance of the late phase of long-term potentiation

PMID:15728837

RGD:1642696

NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855

PTK2

protein tyrosine kinase 2

ISO

PMID:12764094

RGD:2292620

NCBI chr 8:137,330,777...137,677,306
Ensembl chr 8:140,412,773...140,684,898

RETN

resistin

ISO

PMID:22702339

RGD:7207221

NCBI chr19:6,958,536...6,960,032
Ensembl chr19:7,812,942...7,814,909

regulating synaptic membrane exocytosis 1

involved_in

IEA

GO_REF:0000118

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

IEA

GO_REF:0000118

NCBI chr 8:100,156,403...100,894,128

regulating synaptic membrane exocytosis 3

involved_in

IEA

GO_REF:0000118

NCBI chr 1:39,886,961...39,958,519
Ensembl chr 1:41,239,798...41,278,282

regulating synaptic membrane exocytosis 4

involved_in

IEA

GO_REF:0000118

NCBI chr20:41,082,200...41,141,119
Ensembl chr20:42,180,764...42,234,847

S100B

S100 calcium binding protein B

ISO

PMID:12428274

RGD:5509054

NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953

SLC1A3

solute carrier family 1 member 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:73,679,841...73,761,591
Ensembl chr 5:78,960,797...79,042,694

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

SYDE1

synapse defective Rho GTPase homolog 1

acts_upstream_of_or_within

ISO

(PMID:23791195)

PMID:23791195

NCBI chr19:14,640,493...14,648,080
Ensembl chr19:15,625,096...15,631,600

synaptotagmin 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

TNF

tumor necrosis factor

involved_in

ISO
IEA

PMID:11910117

GO_REF:0000107 RGD:1580308

NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381

positive regulation of synaptic transmission, cholinergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IFNG

interferon gamma

ISO

PMID:1900518

RGD:2311499

NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829

LAMA2

laminin subunit alpha 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:126,672,013...127,307,870
Ensembl chr 6:130,781,781...131,415,337

MUSK

muscle associated receptor tyrosine kinase

ISO

PMID:16870737

RGD:2317092

NCBI chr 9:81,814,766...81,947,341
Ensembl chr 9:109,980,748...110,107,480

NALCN

sodium leak channel, non-selective

involved_in

IEA

GO_REF:0000118

NCBI chr13:82,215,094...82,573,501
Ensembl chr13:101,354,054...101,693,223

nerve growth factor receptor

ISO

medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF

PMID:18256260

RGD:5508750

NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966

TAC1

tachykinin precursor 1

ISO

PMID:17949415

RGD:2304335

NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389

TACR1

tachykinin receptor 1

ISO

PMID:17949415

RGD:2304335

NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018

UTS2

urotensin 2

ISO

PMID:15944374

RGD:2306844

NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688

positive regulation of synaptic transmission, dopaminergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARRB2

arrestin beta 2

involved_in

IEA

GO_REF:0000107

NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517

cholinergic receptor nicotinic beta 2 subunit

acts_upstream_of_or_within

ISO

(PMID:15464132)

PMID:15464132

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

FLOT1

flotillin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 6:30,472,839...30,487,809
Ensembl chr 6:31,342,033...31,357,559

PINK1

PTEN induced kinase 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560

positive regulation of synaptic transmission, GABAergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A2a receptor

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

ADRA1A

adrenoceptor alpha 1A

ISO

PMID:14532911

RGD:1625778

NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388

CA2

carbonic anhydrase 2

acts_upstream_of_or_within

ISO

(PMID:23881097)

PMID:23881097

NCBI chr 8:81,991,037...82,009,010
Ensembl chr 8:83,597,440...83,632,580

CA7

carbonic anhydrase 7

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr16:47,161,021...47,170,800
Ensembl chr16:66,262,362...66,271,665

CCKBR

cholecystokinin B receptor

ISO

PMID:17904218

RGD:2311326

NCBI chr11:6,393,435...6,405,821
Ensembl chr11:6,075,816...6,088,145

ERBB4

erb-b2 receptor tyrosine kinase 4

ISO

PMID:17521572

RGD:2289989

NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006

glutamate ionotropic receptor kainate type subunit 1

acts_upstream_of_or_within

ISO

(PMID:17245443)

PMID:12533604 PMID:17245443

RGD:1642497

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

HAP1

huntingtin associated protein 1

involved_in

ISO

PMID:20152113

PMID:20152113

RGD:10047142

NCBI chr17:15,578,658...15,596,313
Ensembl chr17:15,797,949...15,810,299

KIF5B

kinesin family member 5B

involved_in

IEA

GO_REF:0000107

NCBI chr10:32,138,964...32,186,448
Ensembl chr10:32,731,150...32,778,242

NALCN

sodium leak channel, non-selective

involved_in

IEA

GO_REF:0000118

NCBI chr13:82,215,094...82,573,501
Ensembl chr13:101,354,054...101,693,223

neuroligin 1

involved_in

ISO

PMID:12930820

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

neuroligin 2

involved_in

ISO

(PMID:15620359)

PMID:15620359

NCBI chr17:7,438,853...7,454,014

NPS

neuropeptide S

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr10:124,135,616...124,139,845
Ensembl chr10:128,384,897...128,388,217

OXTR

oxytocin receptor

ISO

PMID:11069593

RGD:2304220

NCBI chr 3:8,701,344...8,721,706

PRKCE

protein kinase C epsilon

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313

TAC1

tachykinin precursor 1

ISO

PMID:19261870

RGD:2304250

NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389

TACR1

tachykinin receptor 1

ISO

PMID:19261870

RGD:2304250

NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018

ZDHHC12

zDHHC palmitoyltransferase 12

involved_in

IEA

GO_REF:0000107

NCBI chr 9:99,844,535...99,847,806
Ensembl chr 9:128,510,739...128,514,004

ZDHHC3

zDHHC palmitoyltransferase 3

involved_in

IEA

GO_REF:0000107

NCBI chr 3:44,816,359...44,877,318
Ensembl chr 3:45,880,773...45,931,695

positive regulation of synaptic transmission, glutamatergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCYAP1

adenylate cyclase activating polypeptide 1

ISO

PMID:16483357

RGD:2325299

NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749

adenosine A2a receptor

ISO

K+-evoked glutamate release

PMID:16481441

RGD:1625231

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

CACNG2

calcium voltage-gated channel auxiliary subunit gamma 2

involved_in

IEA

GO_REF:0000118

NCBI chr22:17,475,693...17,618,299
Ensembl chr22:35,317,121...35,454,850

CACNG3

calcium voltage-gated channel auxiliary subunit gamma 3

involved_in

IEA

GO_REF:0000118

Ensembl chr16:24,501,881...24,608,921

CACNG4

calcium voltage-gated channel auxiliary subunit gamma 4

involved_in

IEA

GO_REF:0000118

NCBI chr17:60,900,645...60,969,659

CACNG5

calcium voltage-gated channel auxiliary subunit gamma 5

involved_in

IEA

GO_REF:0000118

NCBI chr17:60,771,501...60,831,190
Ensembl chr17:65,979,469...66,031,723

CACNG7

calcium voltage-gated channel auxiliary subunit gamma 7

involved_in

IEA

GO_REF:0000118

NCBI chr19:50,849,785...50,880,904
Ensembl chr19:59,701,451...59,724,809

CCKBR

cholecystokinin B receptor

ISO

PMID:18088282

RGD:2311325

NCBI chr11:6,393,435...6,405,821
Ensembl chr11:6,075,816...6,088,145

CCL2

C-C motif chemokine ligand 2

involved_in

ISO

(PMID:29993042)

PMID:29993042

NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384

CCR2

C-C motif chemokine receptor 2

involved_in

IEA

GO_REF:0000107

NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312

dopamine receptor D1

acts_upstream_of_or_within

ISO

(PMID:8795639)

PMID:8795639

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

EGFR

epidermal growth factor receptor

ISO

PMID:16648628

RGD:1581898

NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615

GLUL

glutamate-ammonia ligase

ISO

PMID:10696145

RGD:2301558

NCBI chr 1:157,882,258...157,891,562
Ensembl chr 1:161,534,106...161,543,411

GRIA4

glutamate ionotropic receptor AMPA type subunit 4

involved_in

ISO

PMID:11036266

PMID:11036266

RGD:8554601

NCBI chr11:100,498,632...100,873,764
Ensembl chr11:103,983,862...104,355,280

glutamate ionotropic receptor NMDA type subunit 1

involved_in

ISO

PMID:19793963

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

glutamate ionotropic receptor NMDA type subunit 2A

involved_in

ISO

PMID:19793963

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

glutamate ionotropic receptor NMDA type subunit 2B

involved_in

ISO

PMID:19793963

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

glutamate ionotropic receptor NMDA type subunit 2C

involved_in

ISO

PMID:19793963

NCBI chr17:68,787,670...68,807,192

glutamate ionotropic receptor NMDA type subunit 2D

involved_in

ISO

PMID:19793963

NCBI chr19:45,392,258...45,447,004

HDAC6

histone deacetylase 6

ISO

PMID:22331421

RGD:9681553

NCBI chr X:41,099,539...41,122,650
Ensembl chr X:48,960,430...48,982,642

IQSEC2

IQ motif and Sec7 domain ArfGEF 2

ISO

PMID:27009485

RGD:11049506

NCBI chr X:45,447,977...45,535,836
Ensembl chr X:53,557,563...53,644,737

nerve growth factor receptor

ISO

medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF

PMID:18256260

RGD:5508750

NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966

neuroligin 1

involved_in

ISO

PMID:19628693
PMID:19730411

PMID:19628693 PMID:19730411

RGD:8554379 RGD:8554760

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

neuroligin 2

involved_in

ISO

(PMID:15620359)

PMID:15620359

NCBI chr17:7,438,853...7,454,014

neuroligin 3

involved_in

ISO

(PMID:21642956)

PMID:21642956

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

NPS

neuropeptide S

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr10:124,135,616...124,139,845
Ensembl chr10:128,384,897...128,388,217

neurexin 1

involved_in

ISO

(PMID:19822762)
(PMID:19098102)

PMID:19098102 PMID:19822762

NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277

NTRK1

neurotrophic receptor tyrosine kinase 1

ISO

PMID:21550171

RGD:5144124

Ensembl chr 1:136,007,476...136,047,355

neurotrophic receptor tyrosine kinase 2

ISO

PMID:16983663

RGD:1626130

NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678

OXTR

oxytocin receptor

ISO

PMID:18510735

RGD:2304108

NCBI chr 3:8,701,344...8,721,706

PTGS2

prostaglandin-endoperoxide synthase 2

ISO

PMID:18764909

RGD:2300272

NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519

protein tyrosine kinase 2 beta

involved_in

ISO

PMID:11239437

PMID:11239437

RGD:8553497

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

reelin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037

ROR2

receptor tyrosine kinase like orphan receptor 2

ISO

PMID:25825749

RGD:11537351

NCBI chr 9:62,782,183...63,005,626
Ensembl chr 9:90,851,983...90,965,084

SHANK2

SH3 and multiple ankyrin repeat domains 2

involved_in

ISO

(PMID:22699619)

PMID:22699619

NCBI chr11:65,570,677...66,268,139
Ensembl chr11:68,860,606...69,437,925

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21167025), (PMID:21423165), (PMID:21795692)

PMID:21167025 PMID:21423165 PMID:21795692

NCBI chr22:30,951,866...30,973,608

tenascin R

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:150,826,892...151,257,301
Ensembl chr 1:154,532,582...154,615,538

TSHZ3

teashirt zinc finger homeobox 3

involved_in

ISO

(PMID:27668656)

PMID:27668656

NCBI chr19:28,195,740...28,270,265
Ensembl chr19:36,946,685...37,021,531

positive regulation of synaptic transmission, glycinergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC7A10

solute carrier family 7 member 10

involved_in

IEA

GO_REF:0000107

NCBI chr19:30,130,974...30,148,055
Ensembl chr19:38,876,098...38,893,018

positive regulation of synaptic vesicle exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BCL2L1

BCL2 like 1

involved_in

ISO

PMID:23792689

NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585

DNM1L

dynamin 1 like

involved_in

ISO

PMID:23792689

NCBI chr12:53,476,553...53,541,421
Ensembl chr12:56,077,504...56,142,376

neuroligin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

SLC4A8

solute carrier family 4 member 8

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:37,243,593...37,329,083
Ensembl chr12:38,134,574...38,214,036

positive regulation of synaptic vesicle priming

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

regulating synaptic membrane exocytosis 1

involved_in

ISO

PMID:21262469

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

unc-13 homolog B

involved_in

ISO

PMID:21262469

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

postsynaptic modulation of chemical synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATG5

autophagy related 5

involved_in

IEA

GO_REF:0000107

NCBI chr 6:103,997,824...104,140,931
Ensembl chr 6:107,871,208...108,013,807

B-Raf proto-oncogene, serine/threonine kinase

involved_in

ISO

(PMID:16342120)

PMID:16342120

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

CAMK4

calcium/calmodulin dependent protein kinase IV

involved_in

ISO

(PMID:10964952)

PMID:10964952

NCBI chr 5:106,590,803...106,855,592
Ensembl chr 5:112,393,211...112,647,203

CHRM1

cholinergic receptor muscarinic 1

involved_in

IEA

GO_REF:0000107

NCBI chr11:58,261,476...58,274,685
Ensembl chr11:61,614,818...61,616,200

CLMP

CXADR like membrane protein

involved_in

IEA

GO_REF:0000107

NCBI chr11:117,902,792...118,023,936
Ensembl chr11:121,824,398...121,942,055

DCC

DCC netrin 1 receptor

involved_in

IEA

GO_REF:0000107

NCBI chr18:45,717,924...46,913,998
Ensembl chr18:49,268,812...50,255,155

dopamine receptor D1

involved_in

ISO

PMID:15175382

PMID:15175382

RGD:13702391

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

dopamine receptor D2

involved_in

ISO

PMID:15175382

PMID:15175382

RGD:13702391

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

GHRL

ghrelin and obestatin prepropeptide

involved_in

ISO

PMID:26153524

PMID:26153524

RGD:13702301

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

GHSR

growth hormone secretagogue receptor

involved_in

ISO

PMID:26153524

PMID:26153524

RGD:13702301

NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202

GNAO1

G protein subunit alpha o1

involved_in

ISO

(PMID:33535037)

PMID:33535037

NCBI chr16:36,473,852...36,643,789
Ensembl chr16:55,606,920...55,776,619

GRM3

glutamate metabotropic receptor 3

involved_in

IEA

GO_REF:0000107

NCBI chr 7:78,621,634...78,842,532
Ensembl chr 7:92,400,728...92,500,553

IGF1

insulin like growth factor 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177

IGF1R

insulin like growth factor 1 receptor

involved_in

ISO

(PMID:28683263)

PMID:28683263

NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974

INA

internexin neuronal intermediate filament protein alpha

involved_in

IEA

GO_REF:0000107

NCBI chr10:99,877,665...99,890,947
Ensembl chr10:103,340,438...103,353,888

IQSEC1

IQ motif and Sec7 domain ArfGEF 1

involved_in

ISO

(PMID:20547133)

PMID:20547133

NCBI chr 3:12,820,552...13,202,925
Ensembl chr 3:13,167,299...13,235,285

NEFH

neurofilament heavy chain

involved_in

ISO

(PMID:25869803)

PMID:25869803

NCBI chr22:10,525,738...10,536,788

NEFL

neurofilament light chain

involved_in

IEA

GO_REF:0000107

NCBI chr 8:24,218,510...24,224,627
Ensembl chr 8:21,134,533...21,140,694

NGDN

neuroguidin

involved_in

ISO

PMID:22727665

PMID:22727665

RGD:155230789

NCBI chr14:4,288,325...4,296,671
Ensembl chr14:22,382,334...22,390,718

NRGN

neurogranin

involved_in

ISO

PMID:19713936

PMID:19713936

RGD:13702415

NCBI chr11:119,566,934...119,574,248

PLCB1

phospholipase C beta 1

involved_in

IEA

GO_REF:0000107

NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019

protein phosphatase 3 catalytic subunit alpha

involved_in

IEA

GO_REF:0000107

NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394

PPP3R1

protein phosphatase 3 regulatory subunit B, alpha

involved_in

ISO

(PMID:11733061), (PMID:20797538)

PMID:11733061 PMID:20797538

NCBI chr2A:68,227,282...68,300,482

protein kinase cAMP-activated catalytic subunit alpha

involved_in

IEA

GO_REF:0000107

NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205

protein tyrosine kinase 2 beta

involved_in

ISO

PMID:20071509

PMID:20071509

RGD:155230731

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

RASGRF1

Ras protein specific guanine nucleotide releasing factor 1

involved_in

ISO

PMID:14622581

PMID:14622581

RGD:8554730

NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534

RASGRF2

Ras protein specific guanine nucleotide releasing factor 2

involved_in

IEA

GO_REF:0000107

NCBI chr 5:34,048,832...34,326,755
Ensembl chr 5:34,359,896...34,635,488

SLC1A1

solute carrier family 1 member 1

involved_in

IEA

GO_REF:0000107

NCBI chr 9:4,323,124...4,420,193
Ensembl chr 9:4,511,491...4,608,337

SNX14

sorting nexin 14

involved_in

IEA

GO_REF:0000107

NCBI chr 6:83,389,608...83,477,859
Ensembl chr 6:86,671,608...86,759,118

SORCS3

sortilin related VPS10 domain containing receptor 3

involved_in

IEA

GO_REF:0000107

NCBI chr10:101,239,765...101,856,507
Ensembl chr10:104,697,113...105,312,364

SYNPO

synaptopodin

involved_in

ISO

(PMID:12928494), (PMID:25164660)

PMID:12928494 PMID:25164660

NCBI chr 5:146,048,956...146,083,490
Ensembl chr 5:152,046,207...152,085,595

TENT2

terminal nucleotidyltransferase 2

involved_in

ISO

PMID:22727665

PMID:22727665

RGD:155230789

NCBI chr 5:35,622,645...35,696,451
Ensembl chr 5:35,893,841...35,966,932

TRIO

trio Rho guanine nucleotide exchange factor

involved_in

IEA

GO_REF:0000107

NCBI chr 5:14,448,259...14,814,875
Ensembl chr 5:14,423,780...14,654,124

WNT5A

Wnt family member 5A

involved_in

ISO

(PMID:28069946)

PMID:28069946

NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051

presynaptic dense core vesicle exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CADPS

calcium dependent secretion activator

involved_in

ISO

(PMID:25719439)

PMID:25719439

NCBI chr 3:62,321,496...62,797,298

regulating synaptic membrane exocytosis 1

involved_in

ISO

(PMID:31679900)

PMID:31679900

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

synaptosome associated protein 25

involved_in

IEA

GO_REF:0000107

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SYT10

synaptotagmin 10

involved_in

ISO

(PMID:28683263)

PMID:28683263

NCBI chr12:52,761,294...52,830,221
Ensembl chr12:55,364,714...55,429,298

unc-13 homolog A

involved_in

IEA

GO_REF:0000118

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

unc-13 homolog B

involved_in

IEA

GO_REF:0000118

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

presynaptic modulation of chemical synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY1

adenylate cyclase 1

involved_in

IEA

GO_REF:0000107

NCBI chr 7:46,289,042...46,436,839
Ensembl chr 7:46,354,640...46,492,549

adenosine A2a receptor

involved_in

ISO

PMID:15659214

PMID:15659214

RGD:1625642

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

ADORA2B

adenosine A2b receptor

involved_in

IEA

GO_REF:0000107

NCBI chr17:34,849,466...34,880,088

ADRA1A

adrenoceptor alpha 1A

involved_in

ISO

PMID:12548707

PMID:12548707

RGD:13702265

NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388

ADRA2A

adrenoceptor alpha 2A

involved_in

ISO

(PMID:11927164)

PMID:11927164

NCBI chr10:107,669,860...107,673,685

adrenoceptor beta 2

involved_in

ISO

PMID:17175110

PMID:17175110

RGD:5129150

NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892

APBA1

amyloid beta precursor protein binding family A member 1

involved_in

IEA

GO_REF:0000107

NCBI chr 9:55,124,040...55,365,521
Ensembl chr 9:68,191,877...68,275,554

APBA2

amyloid beta precursor protein binding family A member 2

involved_in

ISO

(PMID:17167098)

PMID:17167098

NCBI chr15:167,863...400,296
Ensembl chr15:27,174,217...27,241,529

BACE1

beta-secretase 1

involved_in

IEA

GO_REF:0000107

NCBI chr11:112,120,950...112,151,505
Ensembl chr11:116,054,303...116,084,812

chordin

involved_in

ISO

(PMID:17634368)

NCBI chr 3:181,417,140...181,460,236
Ensembl chr 3:189,898,856...189,908,573

CHRM2

cholinergic receptor muscarinic 2

involved_in

IEA

GO_REF:0000107

NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796

cholinergic receptor nicotinic alpha 3 subunit

involved_in

ISO

PMID:12065717

PMID:12065717

RGD:13702272

NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044

cholinergic receptor nicotinic alpha 4 subunit

involved_in

ISO

(PMID:12944511)

PMID:12944511

NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005

cholinergic receptor nicotinic alpha 5 subunit

involved_in

IEA

GO_REF:0000107

NCBI chr15:57,493,730...57,530,463
Ensembl chr15:76,455,165...76,486,376

CHRNA6

cholinergic receptor nicotinic alpha 6 subunit

involved_in

ISO

(PMID:12944511)

PMID:12944511

NCBI chr 8:42,000,748...42,016,913
Ensembl chr 8:39,444,447...39,460,569

cholinergic receptor nicotinic beta 2 subunit

involved_in

ISO

(PMID:11145999), (PMID:12944511)

PMID:11145999 PMID:12944511

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

CHRNB3

cholinergic receptor nicotinic beta 3 subunit

involved_in

ISO

(PMID:14657161)

PMID:14657161

NCBI chr 8:41,947,062...41,987,159
Ensembl chr 8:39,391,001...39,429,926

CYTH1

cytohesin 1

involved_in

ISO

PMID:9927699

PMID:9927699

RGD:13702340

NCBI chr17:72,749,310...72,857,992
Ensembl chr17:78,295,437...78,358,735

diacylglycerol kinase iota

involved_in

IEA

GO_REF:0000107

NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310

dopamine receptor D1

involved_in

ISO

(PMID:22586226)

PMID:22586226

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

dopamine receptor D2

involved_in

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

dopamine receptor D4

involved_in

ISO

PMID:24155292

PMID:24155292

RGD:13702381

NCBI chr11:640,401...646,775

GIPC1

GIPC PDZ domain containing family member 1

involved_in

IEA

GO_REF:0000107

NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701

GIT1

GIT ArfGAP 1

involved_in

IEA

GO_REF:0000107

NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857

GIT2

GIT ArfGAP 2

involved_in

ISO

(PMID:26637799)

PMID:26637799

NCBI chr12:107,505,791...107,572,641
Ensembl chr12:110,901,303...110,967,489

GLRA3

glycine receptor alpha 3

involved_in

IEA

GO_REF:0000107

NCBI chr 4:166,865,061...167,045,844
Ensembl chr 4:179,083,211...179,279,232

glutamate ionotropic receptor kainate type subunit 1

acts_upstream_of_or_within

ISO

(PMID:11985817)

PMID:11985817

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

GRIN3A

glutamate ionotropic receptor NMDA type subunit 3A

involved_in

IEA

GO_REF:0000107

NCBI chr 9:72,773,866...72,943,790
Ensembl chr 9:100,767,715...100,941,323

GRM2

glutamate metabotropic receptor 2

involved_in

IEA

GO_REF:0000107

NCBI chr 3:51,639,792...51,652,779
Ensembl chr 3:52,873,144...52,884,395

GRM4

glutamate metabotropic receptor 4

involved_in

ISO

(PMID:8815915)

PMID:8815915

NCBI chr 6:33,592,030...33,718,712
Ensembl chr 6:34,696,058...34,830,868

GRM7

glutamate metabotropic receptor 7

involved_in

ISO

(PMID:12065412)

PMID:12065412

NCBI chr 3:6,811,005...7,691,344
Ensembl chr 3:6,907,180...7,933,536

glutamate metabotropic receptor 8

involved_in

ISO

PMID:15275822

PMID:15275822

RGD:6484726

NCBI chr 7:118,430,086...119,249,147

glycogen synthase kinase 3 beta

involved_in

IEA

GO_REF:0000107

NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771

HIP1

huntingtin interacting protein 1

involved_in

ISO

(PMID:17928447)

PMID:17928447

NCBI chr 7:68,281,899...68,464,233

HTR1A

5-hydroxytryptamine receptor 1A

involved_in

ISO

PMID:10381597

PMID:10381597

RGD:13702211

NCBI chr 5:50,045,266...50,049,636
Ensembl chr 5:51,692,416...51,693,684

5-hydroxytryptamine receptor 1B

involved_in

ISO

PMID:17067296

PMID:17067296

RGD:13702319

NCBI chr 6:75,309,078...75,313,747
Ensembl chr 6:78,596,408...78,597,580

HTR2A

5-hydroxytryptamine receptor 2A

involved_in

ISO

PMID:12196574

PMID:12196574

RGD:13702246

NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826

HTR7

5-hydroxytryptamine receptor 7

involved_in

ISO

PMID:26779891

PMID:26779891

RGD:13702205

NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158

LAMP5

lysosomal associated membrane protein family member 5

involved_in

IEA

GO_REF:0000107

NCBI chr20:9,487,971...9,503,912
Ensembl chr20:9,489,849...9,506,137

neuronal acetylcholine receptor subunit alpha-7

involved_in

ISO

PMID:21762741

PMID:21762741

RGD:13702307

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

LOC100980598

adenosine receptor A3

involved_in

ISO

PMID:8987783

PMID:8987783

RGD:13702310

NCBI chr 1:114,144,642...114,225,407
Ensembl chr 1:126,122,352...126,202,396

MYO6

myosin VI

involved_in

ISO

(PMID:16819522)

NCBI chr 6:73,593,794...73,764,352
Ensembl chr 6:76,951,634...77,048,796

nerve growth factor receptor

involved_in

ISO

(PMID:31514753)

PMID:31514753

NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966

noggin

involved_in

IEA

GO_REF:0000107

NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092

NR3C2

nuclear receptor subfamily 3 group C member 2

involved_in

ISO

(PMID:18547242)

PMID:18547242

NCBI chr 4:140,418,624...140,785,180
Ensembl chr 4:152,108,508...152,430,298

NRN1

neuritin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 6:5,832,603...5,841,975
Ensembl chr 6:6,014,000...6,022,870

neurexin 2

involved_in

IEA

GO_REF:0000107

NCBI chr11:59,959,917...60,078,093
Ensembl chr11:63,303,659...63,409,687

neurexin 3

involved_in

ISO

(PMID:26030848)

PMID:26030848

NCBI chr14:58,729,335...60,444,769
Ensembl chr14:78,002,036...79,619,696

OPRM1

opioid receptor mu 1

involved_in

ISO

(PMID:31818459)

PMID:31818459

NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251

PFN2

profilin 2

involved_in

ISO

(PMID:17541406)

PMID:17541406

NCBI chr 3:146,986,364...146,992,558

PRKCA

protein kinase C alpha

involved_in

ISO

(PMID:21658591)

PMID:21658591

NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903

PRKCB

protein kinase C beta

involved_in

IEA

GO_REF:0000107

NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203

PRKCE

protein kinase C epsilon

involved_in

ISO

PMID:26625935

PMID:26625935

RGD:11353024

NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313

protein kinase C gamma

involved_in

IEA

GO_REF:0000107

NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977

RGS19

regulator of G protein signaling 19

involved_in

ISO

(PMID:16819522)

Ensembl chr20:61,987,428...61,993,936

synaptotagmin 12

involved_in

IEA

GO_REF:0000107

NCBI chr11:62,383,485...62,412,451
Ensembl chr11:65,709,808...65,733,010

tumor protein p63 regulated 1 like

involved_in

ISO

PMID:26212709

PMID:26212709

RGD:13792549

NCBI chr 1:2,296,601...2,301,687

YWHAH

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta

involved_in

IEA

GO_REF:0000107

NCBI chr22:12,966,653...12,979,695
Ensembl chr22:30,819,821...30,831,804

protein catabolic process, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RNF216

ring finger protein 216

involved_in

ISO

PMID:24945773

PMID:24945773

RGD:11553202

NCBI chr 7:5,872,118...6,037,073
Ensembl chr 7:5,891,909...6,051,979

regulation of acetylcholine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

ISO

(PMID:12624181)
(PMID:10686170)

PMID:10686170 PMID:12624181

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

cholinergic receptor nicotinic alpha 3 subunit

acts_upstream_of_or_within

ISO

(PMID:16162937)

PMID:16162937

NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044

regulation of acetylcholine-gated cation channel activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cholinergic receptor nicotinic alpha 4 subunit

ISO

PMID:11904236

RGD:704387

NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005

regulation of calcium ion-dependent exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP2A2

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

acts_upstream_of_or_within

ISO

(PMID:21106823)

PMID:21106823

NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923

RAB3 GTPase activating protein catalytic subunit 1

involved_in

ISO

(PMID:16782817)

NCBI chr2B:24,692,363...24,810,685
Ensembl chr2B:139,125,375...139,242,721

regulation of calcium-dependent activation of synaptic vesicle fusion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

calcium voltage-gated channel subunit alpha1 B

involved_in

ISO

PMID:7832825

PMID:7832825

RGD:13792530

NCBI chr 9:108,989,621...109,256,841

ELKS/RAB6-interacting/CAST family member 1

involved_in

ISO

(PMID:25209271)

PMID:25209271

NCBI chr12:1,066,034...1,597,562
Ensembl chr12:1,027,967...1,545,431

ELKS/RAB6-interacting/CAST family member 2

involved_in

IEA

GO_REF:0000107

NCBI chr 3:55,438,875...56,417,072
Ensembl chr 3:56,836,941...57,599,248

PRRT2

proline rich transmembrane protein 2

involved_in

IEA

GO_REF:0000107

Ensembl chr16:30,183,352...30,187,862

RIMBP2

RIMS binding protein 2

involved_in

ISO

(PMID:27671655)

PMID:27671655

NCBI chr12:128,009,575...128,338,009
Ensembl chr12:132,225,056...132,305,103

regulating synaptic membrane exocytosis 1

involved_in

ISO

(PMID:21241895)

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

ISO

(PMID:21241895)

NCBI chr 8:100,156,403...100,894,128

regulation of dopamine uptake involved in synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

dopamine receptor D2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

GDNF

glial cell derived neurotrophic factor

involved_in

IEA

GO_REF:0000107

NCBI chr 5:72,539,374...72,566,918
Ensembl chr 5:77,577,313...77,601,362

TOR1A

torsin family 1 member A

involved_in

ISO

(PMID:15505207)

PMID:15505207

NCBI chr 9:100,940,554...100,951,726

regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DMPK

DM1 protein kinase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:42,779,173...42,791,981
Ensembl chr19:51,316,099...51,329,355

regulation of glutamate secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC38A2

solute carrier family 38 member 2

involved_in

ISS

GO_REF:0000024

NCBI chr12:42,359,637...42,374,251
Ensembl chr12:43,230,007...43,244,343

regulation of long-term neuronal synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGT

angiotensinogen

ISO

PMID:11282364

RGD:1582105

NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044

amyloid beta precursor protein

involved_in

IEA

GO_REF:0000107

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

brain derived neurotrophic factor

ISO

PMID:12201640

RGD:724690

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

CAMK2B

calcium/calmodulin dependent protein kinase II beta

acts_upstream_of_or_within

ISO

(PMID:19503086)

PMID:19503086

NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342

discs large MAGUK scaffold protein 4

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:7,219,911...7,247,509
Ensembl chr17:7,207,483...7,235,985

dopamine receptor D2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

EGR1

early growth response 1

ISO

PMID:16930406

RGD:1626499

NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260

FCGR2B

Fc gamma receptor IIb

involved_in

ISO

(PMID:23921129)

PMID:23921129

NCBI chr 1:137,074,342...137,090,962
Ensembl chr 1:140,882,043...140,890,637

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

glutamate ionotropic receptor NMDA type subunit 1

acts_upstream_of_or_within

ISO

(PMID:10818139)
(PMID:17015831)
(PMID:17313573)

PMID:10818139 PMID:17015831 PMID:17313573

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

glutamate ionotropic receptor NMDA type subunit 2A

ISO

PMID:16904707 PMID:17655746

RGD:1642204 RGD:1642207

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

glutamate ionotropic receptor NMDA type subunit 2B

ISO

PMID:16904707 PMID:17655746

RGD:1642204 RGD:1642207

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

glutamate metabotropic receptor 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953

HRAS

HRas proto-oncogene, GTPase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078

KCNJ10

potassium inwardly rectifying channel subfamily J member 10

acts_upstream_of_or_within

ISO

(PMID:17942730)

PMID:17942730

NCBI chr 1:135,391,321...135,424,100

KRAS

KRAS proto-oncogene, GTPase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335

LNPEP

leucyl and cystinyl aminopeptidase

ISO

PMID:11282364

RGD:1582105

NCBI chr 5:92,247,060...92,348,900
Ensembl chr 5:97,842,110...97,893,876

NETO1

neuropilin and tolloid like 1

involved_in

IEA

GO_REF:0000107

NCBI chr18:66,114,425...66,240,141
Ensembl chr18:69,408,116...69,527,333

neurofibromin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

RAB11A

RAB11A, member RAS oncogene family

ISO

PMID:18045925

RGD:2306457

NCBI chr15:44,810,880...44,833,438
Ensembl chr15:63,088,084...63,108,077

RAB5A

RAB5A, member RAS oncogene family

ISO

PMID:18653660

RGD:2306450

NCBI chr 3:19,866,110...19,903,701
Ensembl chr 3:20,197,067...20,234,579

RAB8A

RAB8A, member RAS oncogene family

ISO

PMID:15297461 PMID:18045925

RGD:2306456 RGD:2306457

NCBI chr19:15,598,029...15,619,988
Ensembl chr19:16,580,720...16,602,189

regulating synaptic membrane exocytosis 1

acts_upstream_of_or_within

ISO

(PMID:11797010)

PMID:11797010

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

SYNGAP1

synaptic Ras GTPase activating protein 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:32,999,408...33,033,067
Ensembl chr 6:34,110,652...34,144,490

SYNGR1

synaptogyrin 1

involved_in

IEA

GO_REF:0000107

NCBI chr22:20,253,936...20,289,470
Ensembl chr22:38,071,261...38,104,931

SYNPO

synaptopodin

involved_in

ISO

(PMID:12928494)

SynGO-UCL

PMID:12928494

NCBI chr 5:146,048,956...146,083,490
Ensembl chr 5:152,046,207...152,085,595

synaptophysin

involved_in

IEA

GO_REF:0000107

NCBI chr X:41,487,538...41,500,039
Ensembl chr X:49,340,021...49,352,420

regulation of long-term synaptic depression

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

activity regulated cytoskeleton associated protein

involved_in

IEA

GO_REF:0000107

NCBI chr 8:139,320,366...139,323,802
Ensembl chr 8:142,367,995...142,369,185

BCL2L1

BCL2 like 1

involved_in

ISO

PMID:23792689

NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585

cannabinoid receptor 1

ISO

PMID:21187978

RGD:596933102

NCBI chr 6:86,017,141...86,044,889

diacylglycerol kinase iota

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310

GNAL

G protein subunit alpha L

ISO

PMID:31678405

RGD:150429833

NCBI chr18:2,420,578...2,615,947

glutamate ionotropic receptor AMPA type subunit 2

ISO

PMID:16311338 PMID:21187978 PMID:37190555

RGD:596933067 RGD:596933068 RGD:596933102

NCBI chr 4:149,566,563...149,712,135
Ensembl chr 4:161,380,933...161,524,376

glutamate ionotropic receptor NMDA type subunit 2B

ISO

PMID:21187978

RGD:596933102

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

glutamate metabotropic receptor 5

ISO

PMID:19136971

RGD:598099564

NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953

PENK

proenkephalin

involved_in

ISO

(PMID:35201898)

PMID:35201898

NCBI chr 8:52,864,388...52,870,144
Ensembl chr 8:50,234,170...50,239,949

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21795692)

PMID:21795692

NCBI chr22:30,951,866...30,973,608

SORCS3

sortilin related VPS10 domain containing receptor 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr10:101,239,765...101,856,507
Ensembl chr10:104,697,113...105,312,364

regulation of long-term synaptic potentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

advanced glycosylation end-product specific receptor

involved_in

IEA

GO_REF:0000107

NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641

activity regulated cytoskeleton associated protein

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 8:139,320,366...139,323,802
Ensembl chr 8:142,367,995...142,369,185

CALB1

calbindin 1

involved_in

IEA

GO_REF:0000118

NCBI chr 8:86,747,702...86,771,995
Ensembl chr 8:88,699,532...88,723,814

CALB2

calbindin 2

involved_in

IEA

GO_REF:0000118

NCBI chr16:53,620,317...53,653,372
Ensembl chr16:71,195,770...71,227,937

CYP46A1

cytochrome P450 family 46 subfamily A member 1

involved_in

IEA

GO_REF:0000107

NCBI chr14:80,309,698...80,352,181
Ensembl chr14:99,628,511...99,671,218

glycogen synthase kinase 3 beta

involved_in

ISO

(PMID:28556462)

PMID:28556462

NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771

LOC100991256

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

ISO

(PMID:24052308)

PMID:24052308

NCBI chr19:51,148,567...51,154,764

NCSTN

nicastrin

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911

neurofibromin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

neuroligin 3

involved_in

ISO

(PMID:21808020)

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

NSG1

neuronal vesicle trafficking associated 1

involved_in

ISO

PMID:15911354

PMID:15911354

RGD:9850096

Ensembl chr 4:4,467,234...4,496,088

PAIP2

poly(A) binding protein interacting protein 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:134,712,834...134,740,747
Ensembl chr 5:140,835,320...140,862,743

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

ISO

(PMID:25242307)

PMID:25242307

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

SCGN

secretagogin, EF-hand calcium binding protein

involved_in

IEA

GO_REF:0000118

NCBI chr 6:25,486,599...25,571,272
Ensembl chr 6:25,812,443...25,862,227

SH3 and multiple ankyrin repeat domains 3

involved_in

ISO

(PMID:21558424)

PMID:21558424

NCBI chr22:30,951,866...30,973,608

YTHDF1

YTH N6-methyladenosine RNA binding protein F1

involved_in

IEA

GO_REF:0000107

NCBI chr20:59,575,703...59,596,447
Ensembl chr20:61,116,645...61,135,769

regulation of modification of synapse structure, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KIF5B

kinesin family member 5B

involved_in

IEA

GO_REF:0000107

NCBI chr10:32,138,964...32,186,448
Ensembl chr10:32,731,150...32,778,242

ZDHHC17

zDHHC palmitoyltransferase 17

involved_in

IEA

GO_REF:0000107

NCBI chr12:74,281,716...74,371,885
Ensembl chr12:77,132,723...77,222,509

regulation of neuromuscular synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BDKRB2

bradykinin receptor B2

involved_in

ISO

(PMID:23846981)

AgBase

PMID:23846981

NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253

regulation of neuronal synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACP4

acid phosphatase 4

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr19:47,754,780...47,760,294
Ensembl chr19:56,649,018...56,653,909

activity regulated cytoskeleton associated protein

involved_in

ISO
IEA

PMID:7857651

GO_REF:0000118 RGD:61538

NCBI chr 8:139,320,366...139,323,802
Ensembl chr 8:142,367,995...142,369,185

BCAN

brevican

ISO

PMID:15935069

RGD:1578390

NCBI chr 1:131,985,310...132,003,068
Ensembl chr 1:135,808,783...135,826,344

BHLHE40

basic helix-loop-helix family member e40

ISO

PMID:9532582

RGD:68312

NCBI chr 3:4,927,487...4,933,215
Ensembl chr 3:5,028,515...5,032,470

BHLHE41

basic helix-loop-helix family member e41

ISO

PMID:9532582

RGD:68312

NCBI chr12:60,194,758...60,199,344

CAMK2A

calcium/calmodulin dependent protein kinase II alpha

acts_upstream_of_or_within

ISO

(PMID:17610578)

PMID:17610578

NCBI chr 5:145,644,164...145,714,143
Ensembl chr 5:151,649,062...151,719,373

chordin

involved_in

ISO

(PMID:17634368)

NCBI chr 3:181,417,140...181,460,236
Ensembl chr 3:189,898,856...189,908,573

CNTN2

contactin 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:180,645,259...180,680,081
Ensembl chr 1:184,931,497...184,966,482

CPEB1

cytoplasmic polyadenylation element binding protein 1

acts_upstream_of_or_within

ISO

(PMID:15169862)

PMID:15169862

NCBI chr15:62,949,264...63,053,994
Ensembl chr15:80,443,096...80,526,948

discs large MAGUK scaffold protein 4

involved_in

ISO

PMID:19596852

PMID:19596852

RGD:21201259

NCBI chr17:7,219,911...7,247,509
Ensembl chr17:7,207,483...7,235,985

EGR2

early growth response 2

ISO

PMID:8619872

RGD:728620

NCBI chr10:59,320,073...59,326,869
Ensembl chr10:61,648,364...61,652,846

EPH receptor B2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118

glutamate ionotropic receptor NMDA type subunit 1

acts_upstream_of_or_within

ISO

(PMID:15576450)

PMID:15576450

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

glycogen synthase kinase 3 beta

ISO

PMID:17329210

RGD:1641844

NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771

JPH3

junctophilin 3

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:17347645)

PMID:17347645

GO_REF:0000107

NCBI chr16:68,276,459...68,379,909
Ensembl chr16:87,596,814...87,700,235

KCNN2

potassium calcium-activated channel subfamily N member 2

ISO

PMID:21521760

RGD:7205439

NCBI chr 5:109,722,916...109,862,747
Ensembl chr 5:115,522,443...115,661,079

MYLK2

myosin light chain kinase 2

ISO

PMID:16515842

RGD:1600505

NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508

NCDN

neurochondrin

involved_in

ISO
IEA

PMID:9398642

GO_REF:0000118 RGD:724406

NCBI chr 1:34,825,694...34,834,729
Ensembl chr 1:36,002,890...36,011,889

noggin

involved_in

IEA

GO_REF:0000107

NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092

NSMF

NMDA receptor synaptonuclear signaling and neuronal migration factor

involved_in

IEA

GO_REF:0000002

NCBI chr 9:108,518,698...108,531,316
Ensembl chr 9:137,482,420...137,495,990

PMCH

pro-melanin concentrating hormone

ISO

PMID:11814630

RGD:729531

NCBI chr12:99,783,925...99,785,292
Ensembl chr12:103,181,497...103,182,616

RAC1

Rac family small GTPase 1

acts_upstream_of_or_within

ISO

(PMID:25865668)

PMID:25865668

NCBI chr 7:7,039,379...7,068,866

RASGRF1

Ras protein specific guanine nucleotide releasing factor 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534

S100B

S100 calcium binding protein B

acts_upstream_of_or_within

ISO

(PMID:11891290)

PMID:11891290

NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

STAR

steroidogenic acute regulatory protein

ISO

PMID:16673174

RGD:1600077

NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544

synaptophysin

involved_in

IEA

GO_REF:0000118

NCBI chr X:41,487,538...41,500,039
Ensembl chr X:49,340,021...49,352,420

VGF

VGF nerve growth factor inducible

ISO

synthetic rat C-terminal VGF peptides

PMID:14645472

RGD:2289061

NCBI chr 7:93,302,956...93,307,892

ZDHHC2

zDHHC palmitoyltransferase 2

involved_in

ISO

PMID:19596852

PMID:19596852

RGD:21201259

NCBI chr 8:16,368,954...16,437,623
Ensembl chr 8:13,343,011...13,380,803

regulation of neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAMK2A

calcium/calmodulin dependent protein kinase II alpha

acts_upstream_of_or_within

ISO

(PMID:12629219)

PMID:12629219

NCBI chr 5:145,644,164...145,714,143
Ensembl chr 5:151,649,062...151,719,373

CPLX1

complexin 1

involved_in

IEA

GO_REF:0000118

NCBI chr 4:889,037...930,046
Ensembl chr 4:819,833...858,953

complexin 2

involved_in

IEA

GO_REF:0000118

NCBI chr 5:171,144,671...171,233,028
Ensembl chr 5:178,115,947...178,128,595

CPLX3

complexin 3

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr15:53,769,138...53,774,330
Ensembl chr15:73,386,826...73,391,991

CPLX4

complexin 4

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr18:52,691,095...52,713,697
Ensembl chr18:55,998,958...56,040,108

dopamine receptor D4

ISO

PMID:15363981

RGD:1625053

NCBI chr11:640,401...646,775

EDN3

endothelin 3

ISO

PMID:12184995

RGD:1299957

NCBI chr20:55,652,770...55,678,486
Ensembl chr20:57,012,926...57,038,570

fragile X messenger ribonucleoprotein 1

involved_in

ISO

PMID:24709664

PMID:24709664

RGD:11059581

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

glutamate metabotropic receptor 8

involved_in

ISO

PMID:16084932

PMID:16084932

RGD:6484727

NCBI chr 7:118,430,086...119,249,147

HCRT

hypocretin neuropeptide precursor

involved_in

ISO
IEA

PMID:15664710

GO_REF:0000118 RGD:1358371

NCBI chr17:15,130,581...15,132,024
Ensembl chr17:15,353,203...15,354,594

KCNC3

potassium voltage-gated channel subfamily C member 3

acts_upstream_of_or_within

ISO

(PMID:15610163)

PMID:15610163

NCBI chr19:47,275,213...47,296,809

KCNC4

potassium voltage-gated channel subfamily C member 4

acts_upstream_of_or_within

ISO

(PMID:15610163)

PMID:15610163

NCBI chr 1:112,860,887...112,884,687
Ensembl chr 1:127,458,968...127,480,182

MCTP1

multiple C2 and transmembrane domain containing 1

involved_in

IEA

GO_REF:0000118

NCBI chr 5:20,071,072...20,669,826
Ensembl chr 5:20,215,917...20,808,014

MCTP2

multiple C2 and transmembrane domain containing 2

involved_in

IEA

GO_REF:0000118

NCBI chr15:72,899,919...73,158,186
Ensembl chr15:92,090,862...92,345,327

myocyte enhancer factor 2C

involved_in

ISO

(PMID:18599438)

PMID:18599438

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

NGF

nerve growth factor

acts_upstream_of_or_within

ISO

(PMID:16298082)

PMID:16298082

NCBI chr 1:87,223,597...87,276,759

neurotrophic receptor tyrosine kinase 2

ISO

PMID:16477614

RGD:1626131

NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678

parkin RBR E3 ubiquitin protein ligase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

RHOT1

ras homolog family member T1

ISO

PMID:24302729

RGD:12904672

NCBI chr17:24,523,047...24,633,559
Ensembl chr17:24,837,093...24,917,310

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

SNCAIP

synuclein alpha interacting protein

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 5:117,692,836...117,847,221
Ensembl chr 5:123,555,073...123,630,921

SNCG

synuclein gamma

acts_upstream_of_or_within

ISO

(PMID:18333965)

PMID:18333965

NCBI chr10:83,383,566...83,391,064

TSPOAP1

TSPO associated protein 1

involved_in

IEA

GO_REF:0000107

NCBI chr17:52,376,707...52,404,160
Ensembl chr17:57,232,244...57,259,669

regulation of postsynaptic neurotransmitter receptor activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BEGAIN

brain enriched guanylate kinase associated

involved_in

ISO

(PMID:27785460)

PMID:27785460

NCBI chr14:81,157,642...81,209,503
Ensembl chr14:100,471,969...100,512,416

CACNG4

calcium voltage-gated channel auxiliary subunit gamma 4

involved_in

ISO

(PMID:17880893)

PMID:17880893

NCBI chr17:60,900,645...60,969,659

CACNG7

calcium voltage-gated channel auxiliary subunit gamma 7

involved_in

ISO

(PMID:23872597)

PMID:23872597

NCBI chr19:50,849,785...50,880,904
Ensembl chr19:59,701,451...59,724,809

cholinergic receptor nicotinic alpha 5 subunit

involved_in

ISO

(PMID:32817066)

PMID:32817066

NCBI chr15:57,493,730...57,530,463
Ensembl chr15:76,455,165...76,486,376

DLGAP2

DLG associated protein 2

involved_in

ISO

(PMID:25071926)

PMID:25071926

NCBI chr 8:5,661,423...6,661,559
Ensembl chr 8:759,261...1,596,858

HOMER1

homer scaffold protein 1

involved_in

ISO

(PMID:11418862)

PMID:11418862

NCBI chr 5:35,794,627...35,936,111
Ensembl chr 5:36,064,665...36,205,928

HOMER3

homer scaffold protein 3

involved_in

ISO

(PMID:11418862)

PMID:11418862

NCBI chr19:18,367,191...18,379,454
Ensembl chr19:19,374,442...19,385,392

LRP8

LDL receptor related protein 8

involved_in

ISO

(PMID:16102539)

PMID:16102539

NCBI chr 1:52,515,534...52,600,390
Ensembl chr 1:54,114,909...54,199,452

NETO1

neuropilin and tolloid like 1

involved_in

ISO

(PMID:26720915)

PMID:26720915

NCBI chr18:66,114,425...66,240,141
Ensembl chr18:69,408,116...69,527,333

NOTCH1

notch receptor 1

involved_in

ISO

(PMID:26635527)

PMID:26635527

NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740

neurexin 2

involved_in

ISO

(PMID:25745399)

PMID:25745399

NCBI chr11:59,959,917...60,078,093
Ensembl chr11:63,303,659...63,409,687

SHISA6

shisa family member 6

involved_in

ISO

(PMID:26931375)

PMID:26931375

NCBI chr17:40,081,234...40,405,916
Ensembl chr17:44,836,825...45,154,241

SHISA7

shisa family member 7

involved_in

ISO

(PMID:29199957)

PMID:29199957

NCBI chr19:52,475,852...52,496,819

SHISA9

shisa family member 9

involved_in

ISO

(PMID:20185686)

PMID:20185686

NCBI chr16:11,833,062...12,494,972
Ensembl chr16:13,258,945...13,591,356

regulation of presynaptic dense core granule exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

P2RX7

purinergic receptor P2X 7

involved_in

ISO

PMID:24037803

PMID:24037803

RGD:13702177

NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068

RAB11B

RAB11B, member RAS oncogene family

involved_in

ISO

PMID:14627637

PMID:14627637

RGD:8554199

NCBI chr19:7,676,095...7,690,177

RAB3A, member RAS oncogene family

involved_in

IEA

GO_REF:0000107

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

unc-13 homolog B

involved_in

ISO

PMID:31679900

PMID:31679900

RGD:155230690

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

regulation of protein catabolic process at postsynapse, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDH1

cadherin 1

involved_in

ISO

PMID:21186356

PMID:21186356

RGD:13702406

NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488

FBXO2

F-box protein 2

involved_in

IEA

GO_REF:0000107

NCBI chr 1:10,408,853...10,415,174
Ensembl chr 1:11,626,713...11,633,171

MDM2

MDM2 proto-oncogene

involved_in

ISO

PMID:14642282

PMID:14642282

RGD:2317402

NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278

NEDD4

NEDD4 E3 ubiquitin protein ligase

involved_in

ISO

PMID:21148011

PMID:21148011

RGD:13702142

NCBI chr15:34,798,880...34,963,823
Ensembl chr15:53,118,411...53,283,076

RNF19A

ring finger protein 19A, RBR E3 ubiquitin protein ligase

involved_in

ISO

(PMID:26553645)

PMID:26553645

NCBI chr 8:96,897,388...96,950,440
Ensembl chr 8:99,070,813...99,123,495

USP8

ubiquitin specific peptidase 8

involved_in

ISO

PMID:25505317

PMID:25505317

RGD:11076799

NCBI chr15:29,374,945...29,451,235
Ensembl chr15:47,713,997...47,790,624

regulation of protein catabolic process at presynapse, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FBXL20

F-box and leucine rich repeat protein 20

involved_in

IEA

GO_REF:0000107

NCBI chr17:17,885,351...18,018,891
Ensembl chr17:18,098,172...18,285,524

regulation of retrograde trans-synaptic signaling by endocanabinoid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABHD6

abhydrolase domain containing 6, acylglycerol lipase

involved_in

IEA

GO_REF:0000107

NCBI chr 3:58,172,334...58,227,531
Ensembl chr 3:59,586,573...59,641,824

FABP5

fatty acid binding protein 5

involved_in

ISO

(PMID:29531087)

PMID:29531087

NCBI chr 8:77,803,369...77,807,630
Ensembl chr 8:79,426,684...79,430,879

MGLL

monoglyceride lipase

involved_in

IEA

GO_REF:0000107

NCBI chr 3:124,733,770...124,865,302
Ensembl chr 3:132,040,430...132,171,731

PLCB1

phospholipase C beta 1

involved_in

IEA

GO_REF:0000107

NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019

regulation of short-term neuronal synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP1A3

ATPase Na+/K+ transporting subunit alpha 3

acts_upstream_of_or_within

ISO

(PMID:25523819)

PMID:25523819

NCBI chr19:38,854,243...38,882,034
Ensembl chr19:47,358,281...47,384,716

brain derived neurotrophic factor

ISO

PMID:12201640

RGD:724690

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

glutamate ionotropic receptor kainate type subunit 1

ISO

PMID:17395219

RGD:1642466

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within
involved_in

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

GSG1L

GSG1 like

acts_upstream_of_or_within

IEA

GO_REF:0000107

KMT2A

lysine methyltransferase 2A

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:113,273,198...113,364,404
Ensembl chr11:117,204,820...117,290,100

LOC117978823

battenin

involved_in

ISO

(PMID:29135436), (PMID:29780879)

PMID:29135436 PMID:29780879

PTPRF interacting protein alpha 3

ISO

PMID:11797009

RGD:633666

NCBI chr19:46,130,396...46,162,065
Ensembl chr19:55,056,824...55,089,124

RAB3A, member RAS oncogene family

involved_in

IEA

GO_REF:0000107

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

RAB3 GTPase activating protein catalytic subunit 1

involved_in

ISO

(PMID:16782817)

NCBI chr2B:24,692,363...24,810,685
Ensembl chr2B:139,125,375...139,242,721

SHISA6

shisa family member 6

involved_in

IEA

GO_REF:0000118

NCBI chr17:40,081,234...40,405,916
Ensembl chr17:44,836,825...45,154,241

SHISA9

shisa family member 9

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr16:11,833,062...12,494,972
Ensembl chr16:13,258,945...13,591,356

SLC4A10

solute carrier family 4 member 10

involved_in

IEA

GO_REF:0000107

NCBI chr2B:48,917,958...49,278,724
Ensembl chr2B:166,371,645...166,647,554

SLC8A2

solute carrier family 8 member A2

involved_in

IEA

GO_REF:0000107

NCBI chr19:44,420,146...44,464,242
Ensembl chr19:53,077,857...53,113,830

SYAP1

synapse associated protein 1

involved_in

IEA

GO_REF:0000118

NCBI chr X:9,339,052...9,384,940
Ensembl chr X:16,706,612...16,747,610

SYNGR1

synaptogyrin 1

involved_in

IEA

GO_REF:0000107

NCBI chr22:20,253,936...20,289,470
Ensembl chr22:38,071,261...38,104,931

synaptophysin

involved_in

IEA

GO_REF:0000107

NCBI chr X:41,487,538...41,500,039
Ensembl chr X:49,340,021...49,352,420

unc-13 homolog A

acts_upstream_of_or_within

ISO

(PMID:11832228)

PMID:11832228

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

PMID:11832228 PMID:19700493

unc-13 homolog B

acts_upstream_of_or_within
involved_in

ISO

(PMID:11832228)
(PMID:19700493)

MGI
ParkinsonsUK-UCL

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

regulation of spontaneous synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

advanced glycosylation end-product specific receptor

involved_in

IEA

GO_REF:0000107

NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641

amyloid beta precursor protein

involved_in

IEA

GO_REF:0000107

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

ITGB1

integrin subunit beta 1

acts_upstream_of_or_within_negative_effect

ISO

(PMID:25716834)

PMID:25716834

NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031

SLC12A2

solute carrier family 12 member 2

acts_upstream_of_or_within

ISO

PMID:16227993
(PMID:16227993)
(PMID:25716834)

PMID:16227993 PMID:25716834

RGD:1580584

NCBI chr 5:123,499,267...123,603,777
Ensembl chr 5:129,262,134...129,364,563

regulation of synaptic activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGRN

agrin

acts_upstream_of_or_within

ISO

(PMID:24753587)

PMID:24753587

Ensembl chr 1:936,000...966,808

myocyte enhancer factor 2C

involved_in

ISO

(PMID:18599437), (PMID:18599438), (PMID:22496871)

PMID:18599437 PMID:18599438 PMID:22496871

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

SYBU

syntabulin

ISO

PMID:19828815

RGD:13217418

NCBI chr 8:106,223,046...106,340,418
Ensembl chr 8:108,368,117...108,483,927

regulation of synaptic plasticity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACE

angiotensin I converting enzyme

involved_in

IEA

GO_REF:0000107

NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853

ADGRB1

adhesion G protein-coupled receptor B1

involved_in

IEA

GO_REF:0000107

NCBI chr 8:139,154,065...139,251,115
Ensembl chr 8:142,220,827...142,301,070

ALG13

ALG13 UDP-N-acetylglucosaminyltransferase subunit

acts_upstream_of_or_within

ISO

(PMID:30872163)

PMID:30872163

NCBI chr X:100,794,882...100,874,083
Ensembl chr X:111,253,717...111,332,534

ATF4

activating transcription factor 4

involved_in

ISO

(PMID:12925279)

PMID:12925279

NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249

ATP2B2

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

ISO

(PMID:17409239)

PMID:17409239

NCBI chr 3:10,260,556...10,643,346
Ensembl chr 3:10,611,619...10,738,006

BAIAP2

BAR/IMD domain containing adaptor protein 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:75,460,491...75,542,700
Ensembl chr17:81,187,021...81,269,714

brain derived neurotrophic factor

acts_upstream_of_or_within

ISO

(PMID:16819522), (PMID:17442827)

PMID:16819522 PMID:17442827

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

BEST1

bestrophin 1

involved_in

IEA

GO_REF:0000107

NCBI chr11:57,314,430...57,329,450
Ensembl chr11:60,672,835...60,687,417

BRSK1

BR serine/threonine kinase 1

involved_in

IEA

GO_REF:0000107

NCBI chr19:52,326,538...52,355,060
Ensembl chr19:61,021,493...61,045,659

C23H22orf39

chromosome 23 C22orf39 homolog

involved_in

IEA

GO_REF:0000107

NCBI chr22:2,200,164...2,207,473
Ensembl chr22:17,875,330...17,882,694

CALB1

calbindin 1

ISO

PMID:15318329

RGD:1358474

NCBI chr 8:86,747,702...86,771,995
Ensembl chr 8:88,699,532...88,723,814

CALB2

calbindin 2

involved_in

IEA

GO_REF:0000107

NCBI chr16:53,620,317...53,653,372
Ensembl chr16:71,195,770...71,227,937

CALHM2

calcium homeostasis modulator family member 2

involved_in

IEA

GO_REF:0000107

NCBI chr10:100,044,254...100,049,892
Ensembl chr10:103,505,252...103,511,097

CD2AP

CD2 associated protein

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:47,065,284...47,210,746
Ensembl chr 6:48,328,863...48,474,163

cyclin dependent kinase 5

involved_in

ISO

PMID:18498738

PMID:11675505 PMID:18498738

RGD:69667 RGD:8553496

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

CHRDL1

chordin like 1

involved_in

IEA

GO_REF:0000107

NCBI chr X:99,781,730...99,915,778
Ensembl chr X:110,251,525...110,375,289

cholinergic receptor nicotinic alpha 2 subunit

acts_upstream_of_or_within

ISO

(PMID:32467358)

PMID:32467358

NCBI chr 8:26,729,767...26,749,277
Ensembl chr 8:23,932,846...23,952,377

CPEB3

cytoplasmic polyadenylation element binding protein 3

involved_in

ISO

(PMID:24155305)

PMID:24155305

NCBI chr10:88,794,186...89,038,808
Ensembl chr10:92,320,240...92,506,089

CRHR1

corticotropin releasing hormone receptor 1

ISO

PMID:17079348

RGD:1626232

NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208

CTNND2

catenin delta 2

acts_upstream_of_or_within

ISO

(PMID:15380068)

PMID:15380068

NCBI chr 5:11,288,652...12,227,569

DAG1

dystroglycan 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:49,396,180...49,464,689
Ensembl chr 3:50,640,615...50,703,852

EIF4EBP2

eukaryotic translation initiation factor 4E binding protein 2

involved_in

ISO

(PMID:16237163), (PMID:20347422)

PMID:16237163 PMID:20347422

NCBI chr10:66,879,744...66,903,027
Ensembl chr10:69,406,745...69,423,249

ELKS/RAB6-interacting/CAST family member 1

involved_in

IEA

GO_REF:0000118

NCBI chr12:1,066,034...1,597,562
Ensembl chr12:1,027,967...1,545,431

ELKS/RAB6-interacting/CAST family member 2

involved_in

IEA

GO_REF:0000118

NCBI chr 3:55,438,875...56,417,072
Ensembl chr 3:56,836,941...57,599,248

F2R

coagulation factor II thrombin receptor

involved_in

IEA

GO_REF:0000107

NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,110,170...39,129,688
Ensembl chr 5:39,110,170...39,129,688

FGF14

fibroblast growth factor 14

acts_upstream_of_or_within

ISO

PMID:23831029

PMID:23831029

RGD:10047342

NCBI chr13:82,869,491...83,563,099
Ensembl chr13:102,016,568...102,696,330

GIPC1

GIPC PDZ domain containing family member 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701

glutamate ionotropic receptor AMPA type subunit 1

involved_in

ISO

PMID:12536214

PMID:12536214

RGD:8553676

NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660

glutamate ionotropic receptor NMDA type subunit 1

acts_upstream_of_or_within
involved_in

ISO

(PMID:15003177), (PMID:8980238)
(PMID:12008020), (PMID:14602821), (PMID:15003177)
(PMID:8980239), (PMID:9246451)

MGI
UniProt

PMID:8980238 PMID:8980239 PMID:9246451 PMID:12008020 PMID:14602821 More...

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

glutamate ionotropic receptor NMDA type subunit 2A

involved_in

IEA

GO_REF:0000107

NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167

PMID:8789948 PMID:11719203 PMID:16710293

glutamate ionotropic receptor NMDA type subunit 2B

acts_upstream_of_or_within
involved_in

ISO

(PMID:11719203)
(PMID:8789948)
(PMID:16710293)

MGI
UniProt

NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799

glutamate ionotropic receptor NMDA type subunit 2C

involved_in

IEA

GO_REF:0000107

NCBI chr17:68,787,670...68,807,192

glutamate ionotropic receptor NMDA type subunit 2D

involved_in

ISO

(PMID:34637787)

PMID:34637787

NCBI chr19:45,392,258...45,447,004

GRIN3A

glutamate ionotropic receptor NMDA type subunit 3A

involved_in

ISO

PMID:25009255

PMID:25009255

RGD:408345217

NCBI chr 9:72,773,866...72,943,790
Ensembl chr 9:100,767,715...100,941,323

GRIN3B

glutamate ionotropic receptor NMDA type subunit 3B

involved_in

IEA

GO_REF:0000107

Ensembl chr19:975,872...982,757

HRH1

histamine receptor H1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:11,074,451...11,199,871
Ensembl chr 3:11,541,294...11,542,757

HRH2

histamine receptor H2

acts_upstream_of_or_within

ISO

(PMID:17145090)

PMID:17145090

NCBI chr 5:171,004,893...171,057,539
Ensembl chr 5:177,928,039...177,931,566

HTT

huntingtin

acts_upstream_of_or_within

ISO

(PMID:10196373)
(PMID:17442827)

PMID:10196373 PMID:17442827

NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730

immunoglobulin superfamily member 11

involved_in

IEA

GO_REF:0000107

NCBI chr 3:116,033,187...116,153,134
Ensembl chr 3:122,948,246...122,972,742

ITPKA

inositol-trisphosphate 3-kinase A

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr15:20,434,532...20,444,389
Ensembl chr15:38,675,600...38,684,779

JPH3

junctophilin 3

involved_in

IEA

GO_REF:0000118

NCBI chr16:68,276,459...68,379,909
Ensembl chr16:87,596,814...87,700,235

JPH4

junctophilin 4

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr14:4,386,487...4,397,552
Ensembl chr14:22,479,813...22,490,924

KAT2A

lysine acetyltransferase 2A

involved_in

IEA

GO_REF:0000107

NCBI chr17:15,194,414...15,202,818
Ensembl chr17:15,416,075...15,424,197

KCNQ2

potassium voltage-gated channel subfamily Q member 2

acts_upstream_of_or_within

ISO

(PMID:18483067)

PMID:18483067

Ensembl chr20:61,325,365...61,395,266

KCNQ3

potassium voltage-gated channel subfamily Q member 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 8:128,769,930...129,134,671
Ensembl chr 8:131,755,454...131,815,237

LARGE xylosyl- and glucuronyltransferase 1

acts_upstream_of_or_within

ISO

(PMID:24753587)

PMID:24753587

NCBI chr22:14,077,463...14,929,250

LYPD6

LY6/PLAUR domain containing 6

acts_upstream_of_or_within

ISO

(PMID:32467358)

PMID:32467358

NCBI chr2B:10,392,962...10,536,125
Ensembl chr2B:153,792,413...153,828,297

LZTS1

leucine zipper tumor suppressor 1

involved_in

ISO
IEA

PMID:15703396

GO_REF:0000118 RGD:1600102

NCBI chr 8:19,471,361...19,529,437
Ensembl chr 8:16,418,496...16,476,111

MAP1A

microtubule associated protein 1A

involved_in

ISO

(PMID:26609151)

PMID:26609151

NCBI chr15:22,472,641...22,493,293
Ensembl chr15:40,627,099...40,647,752

methyl-CpG binding protein 2

acts_upstream_of_or_within

ISO

(PMID:16399702)

PMID:16399702

NCBI chr X:143,571,864...143,647,192
Ensembl chr X:153,465,204...153,527,854

myocyte enhancer factor 2C

involved_in

ISO

(PMID:22496871)

PMID:22496871

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

MYO6

myosin VI

acts_upstream_of_or_within

ISO

(PMID:16819522)

NCBI chr 6:73,593,794...73,764,352
Ensembl chr 6:76,951,634...77,048,796

NFATC4

nuclear factor of activated T cells 4

ISO

PMID:12954875

RGD:1580247

NCBI chr14:5,141,699...5,156,021
Ensembl chr14:23,266,702...23,279,249

NOLC1

nucleolar and coiled-body phosphoprotein 1

acts_upstream_of_or_within

ISO

(PMID:24794856)

PMID:24794856

NCBI chr10:98,756,307...98,767,917
Ensembl chr10:102,223,956...102,233,760

neuronal PAS domain protein 4

involved_in

IEA

GO_REF:0000107

NCBI chr11:61,778,329...61,784,010
Ensembl chr11:65,103,097...65,108,825

purinergic receptor P2X 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:52,579,190...52,614,329
Ensembl chr 3:160,070,875...160,106,120

PLAT

plasminogen activator, tissue type

ISO

PMID:12070304

RGD:628337

NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779

polo like kinase 2

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793

PSEN1

presenilin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876

PSEN2

presenilin 2

acts_upstream_of_or_within

ISO

(PMID:15066262)

PMID:15066262

NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295

pleiotrophin

involved_in

IEA

GO_REF:0000107

NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623

RAPGEF2

Rap guanine nucleotide exchange factor 2

involved_in

ISO

PMID:21382555

NCBI chr 4:151,419,402...151,680,769
Ensembl chr 4:163,316,396...163,487,495

RARA

retinoic acid receptor alpha

ISO

PMID:18957222

RGD:2314254

NCBI chr17:16,932,485...16,980,958

RASGRF1

Ras protein specific guanine nucleotide releasing factor 1

involved_in

ISO

PMID:21382555

NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534

RGS19

regulator of G protein signaling 19

acts_upstream_of_or_within

ISO

(PMID:16819522)

Ensembl chr20:61,987,428...61,993,936

regulating synaptic membrane exocytosis 1

involved_in

IEA

GO_REF:0000118

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

IEA

GO_REF:0000118

NCBI chr 8:100,156,403...100,894,128

regulating synaptic membrane exocytosis 3

involved_in

IEA

GO_REF:0000118

NCBI chr 1:39,886,961...39,958,519
Ensembl chr 1:41,239,798...41,278,282

regulating synaptic membrane exocytosis 4

involved_in

IEA

GO_REF:0000118

NCBI chr20:41,082,200...41,141,119
Ensembl chr20:42,180,764...42,234,847

SCT

secretin

involved_in

ISO

(PMID:18534766)

PMID:18534766

NCBI chr11:632,073...634,296

SCTR

secretin receptor

involved_in

ISO

(PMID:17008357)

PMID:17008357

NCBI chr2B:6,374,400...6,458,595
Ensembl chr2B:119,952,714...120,036,326

SH3 and multiple ankyrin repeat domains 3

acts_upstream_of_or_within

ISO

(PMID:21558424)

PMID:21558424

NCBI chr22:30,951,866...30,973,608

SIPA1L1

signal induced proliferation associated 1 like 1

involved_in

ISO

PMID:21382555
PMID:18498738

PMID:15703396 PMID:18498738 PMID:21382555

RGD:1600102 RGD:7241548 RGD:8553496

NCBI chr14:51,909,444...52,328,719
Ensembl chr14:71,038,600...71,192,916

SLC38A1

solute carrier family 38 member 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:42,464,360...42,550,324
Ensembl chr12:43,362,597...43,413,616

SYNGAP1

synaptic Ras GTPase activating protein 1

involved_in

ISO

PMID:21382555

NCBI chr 6:32,999,408...33,033,067
Ensembl chr 6:34,110,652...34,144,490

UBE3A

ubiquitin protein ligase E3A

involved_in

ISO

(PMID:30020076)

PMID:30020076

NCBI chr15:4,494,029...4,595,415
Ensembl chr15:22,747,075...22,825,459

VGF

VGF nerve growth factor inducible

involved_in

IEA

GO_REF:0000118

NCBI chr 7:93,302,956...93,307,892

VPS13A

vacuolar protein sorting 13 homolog A

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 9:47,424,921...47,668,150
Ensembl chr 9:76,032,286...76,269,636

YWHAG

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

involved_in

ISO

(PMID:11824616)

PMID:11824616

NCBI chr 7:67,661,589...67,693,814

ZZEF1

zinc finger ZZ-type and EF-hand domain containing 1

acts_upstream_of_or_within

ISO

(PMID:33158444)
(PMID:25709106)

PMID:25709106 PMID:33158444

NCBI chr17:4,059,659...4,197,386
Ensembl chr17:4,054,952...4,188,735

regulation of synaptic scaling

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GRIP1

glutamate receptor interacting protein 1

ISO

PMID:26109571

RGD:152995513

NCBI chr12:21,841,611...22,562,418
Ensembl chr12:22,744,177...23,069,480

regulation of synaptic transmission, cholinergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAMK2B

calcium/calmodulin dependent protein kinase II beta

acts_upstream_of_or_within

ISO

(PMID:19332541)

PMID:19332541

NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342

regulation of synaptic transmission, dopaminergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cholinergic receptor nicotinic beta 2 subunit

acts_upstream_of_or_within

ISO

(PMID:16772172)

PMID:16772172

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

CNTNAP4

contactin associated protein family member 4

involved_in

ISO

(PMID:24870235)

PMID:24870235

NCBI chr16:56,512,541...57,138,499
Ensembl chr16:76,199,706...76,484,466

neuronal acetylcholine receptor subunit alpha-7

acts_upstream_of_or_within

ISO

(PMID:16772172)

PMID:16772172

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

PNKD

PNKD metallo-beta-lactamase domain containing

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:105,529,775...105,606,207
Ensembl chr2B:224,127,504...224,204,046

regulation of synaptic transmission, GABAergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BAIAP3

BAI1 associated protein 3

involved_in

IEA

GO_REF:0000107

Ensembl chr16:1,390,160...1,403,978

cannabinoid receptor 1

ISO

PMID:19725112

RGD:2314643

NCBI chr 6:86,017,141...86,044,889

CNTNAP4

contactin associated protein family member 4

involved_in

ISO

(PMID:24870235)

PMID:24870235

NCBI chr16:56,512,541...57,138,499
Ensembl chr16:76,199,706...76,484,466

DBI

diazepam binding inhibitor, acyl-CoA binding protein

acts_upstream_of_or_within

ISO

PMID:3456171

PMID:3456171

RGD:8554715

NCBI chr2B:6,309,048...6,314,660
Ensembl chr2B:119,887,728...119,892,986

dopamine receptor D2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

KCNK2

potassium two pore domain channel subfamily K member 2

involved_in

IEA

GO_REF:0000107

NCBI chr 1:190,576,180...190,807,367
Ensembl chr 1:195,430,994...195,662,840

KRAS

KRAS proto-oncogene, GTPase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335

LOC117978823

battenin

involved_in

ISO

(PMID:29135436)

PMID:29135436

neurofibromin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

NISCH

nischarin

ISO

PMID:16467528

RGD:1582692

NCBI chr 3:52,397,576...52,435,127
Ensembl chr 3:53,626,317...53,662,567

neuronal PAS domain protein 4

involved_in

IEA

GO_REF:0000107

NCBI chr11:61,778,329...61,784,010
Ensembl chr11:65,103,097...65,108,825

PHF24

PHD finger protein 24

acts_upstream_of_or_within

ISO

(PMID:25242222)

PMID:25242222

NCBI chr 9:34,735,800...34,829,555
Ensembl chr 9:35,611,517...35,635,964

PLCL1

phospholipase C like 1 (inactive)

involved_in
acts_upstream_of_or_within

IEA

InterPro
Ensembl
TreeGrafter

GO_REF:0000107 GO_REF:0000118

NCBI chr2B:85,054,907...85,397,171
Ensembl chr2B:202,947,927...203,286,649

PLCL2

phospholipase C like 2

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000002 GO_REF:0000107 GO_REF:0000118

NCBI chr 3:16,736,430...17,015,531
Ensembl chr 3:17,154,500...17,351,287

phosphatase and tensin homolog

acts_upstream_of_or_within

ISO

(PMID:24875179)

PMID:24875179

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

SLC38A1

solute carrier family 38 member 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:42,464,360...42,550,324
Ensembl chr12:43,362,597...43,413,616

USP46

ubiquitin specific peptidase 46

involved_in

IEA

GO_REF:0000107

NCBI chr 4:71,305,286...71,373,257
Ensembl chr 4:77,861,053...77,920,759

regulation of synaptic transmission, glutamatergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cyclin dependent kinase 5

involved_in

IEA

GO_REF:0000107

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

cannabinoid receptor 1

ISO

PMID:19725112

RGD:2314643

NCBI chr 6:86,017,141...86,044,889

diacylglycerol kinase iota

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310

DISC1

DISC1 scaffold protein

acts_upstream_of_or_within

ISO

PMID:24706880

PMID:24706880

RGD:11344933

NCBI chr 1:207,180,513...207,594,684
Ensembl chr 1:212,265,520...212,612,079

DKK1

dickkopf WNT signaling pathway inhibitor 1

involved_in

ISO

(PMID:25318560)

PMID:25318560

NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776

FRRS1L

ferric chelate reductase 1 like

acts_upstream_of_or_within

ISO

(PMID:29276473)

PMID:29276473

NCBI chr 9:80,283,385...80,320,293

FMR1 autosomal homolog 1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:177,948,040...178,012,705

glutamate ionotropic receptor AMPA type subunit 2

involved_in

ISO

PMID:9697854

PMID:9697854

RGD:8553822

NCBI chr 4:149,566,563...149,712,135
Ensembl chr 4:161,380,933...161,524,376

GRM1

glutamate metabotropic receptor 1

involved_in

ISO

PMID:11530226

PMID:11530226

RGD:8553469

NCBI chr 6:143,819,364...144,231,304
Ensembl chr 6:148,537,036...148,947,047

HOMER1

homer scaffold protein 1

involved_in

ISO

PMID:19345194

PMID:19345194

RGD:8553291

NCBI chr 5:35,794,627...35,936,111
Ensembl chr 5:36,064,665...36,205,928

LOC117978823

battenin

involved_in

ISO

(PMID:29135436)

PMID:29135436

leucine rich repeat kinase 2

involved_in

IEA

GO_REF:0000107

NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462

MAPK8IP2

mitogen-activated protein kinase 8 interacting protein 2

involved_in

IEA

GO_REF:0000107

NCBI chr22:30,846,613...30,857,737
Ensembl chr22:49,957,769...49,966,986

myocyte enhancer factor 2C

involved_in

ISO

(PMID:18599438)

PMID:18599438

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

neuroligin 3

involved_in

ISO

(PMID:21808020)

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

OPHN1

oligophrenin 1

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr X:57,288,297...57,674,685
Ensembl chr X:67,359,364...67,739,114

PLPPR4

phospholipid phosphatase related 4

involved_in

IEA

GO_REF:0000107

NCBI chr 1:101,919,714...101,965,146
Ensembl chr 1:100,640,187...100,685,483

protein kinase cAMP-activated catalytic subunit alpha

ISO

PMID:12562968

RGD:1580676

NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205

PSEN1

presenilin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876

RNF167

ring finger protein 167

involved_in

IEA

GO_REF:0000107

NCBI chr17:4,988,275...4,993,423
Ensembl chr17:4,975,849...4,981,335

SERPINE2

serpin family E member 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040

synaptotagmin 1

involved_in

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

tumor protein p63 regulated 1 like

involved_in

ISO

PMID:26212709

PMID:26212709

RGD:13792549

NCBI chr 1:2,296,601...2,301,687

UCN

urocortin

ISO

PMID:15102917

RGD:1642787

NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669

regulation of synaptic transmission, glycinergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC6A9

solute carrier family 6 member 9

involved_in

IEA

GO_REF:0000107

NCBI chr 1:43,298,326...43,333,345
Ensembl chr 1:44,664,839...44,704,882

regulation of synaptic vesicle docking

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAMK2A

calcium/calmodulin dependent protein kinase II alpha

involved_in

ISO

(PMID:17660813)

PMID:17660813

NCBI chr 5:145,644,164...145,714,143
Ensembl chr 5:151,649,062...151,719,373

regulation of synaptic vesicle exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CACNA1E

calcium voltage-gated channel subunit alpha1 E

involved_in

ISO

PMID:19193890

PMID:19193890

RGD:13792544

NCBI chr 1:156,796,855...157,296,987
Ensembl chr 1:160,628,089...160,949,270

CACNB4

calcium voltage-gated channel auxiliary subunit beta 4

involved_in

IEA

GO_REF:0000107

NCBI chr2B:39,137,777...39,399,007
Ensembl chr2B:156,379,469...156,639,328

CALM1

calmodulin 1

involved_in

ISO

PMID:23792689

NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135

CALM2

calmodulin 2

involved_in

ISO

PMID:23792689

NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697

CALM3

calmodulin 3

involved_in

ISO

PMID:23792689

NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135

CASK

calcium/calmodulin dependent serine protein kinase

involved_in

IEA

GO_REF:0000107

NCBI chr X:33,967,329...34,374,385
Ensembl chr X:41,659,295...42,066,570

CSPG5

chondroitin sulfate proteoglycan 5

involved_in

IEA

GO_REF:0000107

NCBI chr 3:47,464,341...47,482,910
Ensembl chr 3:48,564,199...48,580,048

DTNBP1

dystrobrevin binding protein 1

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256

dishevelled segment polarity protein 1

involved_in

IEA

GO_REF:0000107

NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008

FBXL20

F-box and leucine rich repeat protein 20

involved_in

IEA

GO_REF:0000107

NCBI chr17:17,885,351...18,018,891
Ensembl chr17:18,098,172...18,285,524

FBXO45

F-box protein 45

involved_in

IEA

GO_REF:0000107

NCBI chr 3:193,913,712...193,934,123
Ensembl chr 3:203,856,374...203,876,537

GIT1

GIT ArfGAP 1

involved_in

IEA

GO_REF:0000107

NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857

GIT2

GIT ArfGAP 2

involved_in

ISO

(PMID:26637799)

PMID:26637799

NCBI chr12:107,505,791...107,572,641
Ensembl chr12:110,901,303...110,967,489

GPR151

G protein-coupled receptor 151

involved_in

IEA

GO_REF:0000107

NCBI chr 5:141,960,691...141,963,922
Ensembl chr 5:147,975,633...147,976,892

5-hydroxytryptamine receptor 1B

involved_in

ISO

PMID:17067296

PMID:17067296

RGD:13702319

NCBI chr 6:75,309,078...75,313,747
Ensembl chr 6:78,596,408...78,597,580

HTR1D

5-hydroxytryptamine receptor 1D

involved_in

ISO

PMID:8522955

PMID:8522955

RGD:155230787

NCBI chr 1:22,378,262...22,403,918
Ensembl chr 1:23,371,492...23,372,625

KCNH1

potassium voltage-gated channel subfamily H member 1

involved_in

ISO

(PMID:25556795)

PMID:25556795

NCBI chr 1:186,233,881...186,696,509
Ensembl chr 1:191,107,256...191,562,766

leucine rich repeat kinase 2

involved_in

IEA

GO_REF:0000107

NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462

NCS1

neuronal calcium sensor 1

involved_in

ISO

PMID:12947410

PMID:12947410

RGD:13702435

NCBI chr 9:101,299,724...101,364,897
Ensembl chr 9:129,950,921...130,016,257

NPY

neuropeptide Y

involved_in

ISO

PMID:16026936

PMID:16026936

RGD:155230755

NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657

NPY1R

neuropeptide Y receptor Y1

involved_in

ISO

PMID:16026936

PMID:16026936

RGD:155230755

NCBI chr 4:155,583,870...155,604,336
Ensembl chr 4:167,372,310...167,381,597

P2RX1

purinergic receptor P2X 1

involved_in

ISO

PMID:16000618

NCBI chr17:3,944,636...3,965,260
Ensembl chr17:3,935,982...3,956,595

purinergic receptor P2X 2

involved_in

ISO

PMID:16000618

NCBI chr12:129,969,793...129,974,399

P2RY1

purinergic receptor P2Y1

involved_in

ISO

PMID:16000618

NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813

P2RY2

purinergic receptor P2Y2

involved_in

ISO

PMID:16000618

NCBI chr11:68,294,366...68,319,118
Ensembl chr11:71,532,958...71,534,091

P2RY4

pyrimidinergic receptor P2Y4

involved_in

ISO

PMID:16000618

NCBI chr X:59,526,621...59,528,248
Ensembl chr X:69,586,340...69,587,437

PFN2

profilin 2

acts_upstream_of_or_within

ISO

(PMID:17541406)

PMID:17541406

NCBI chr 3:146,986,364...146,992,558

PPFIA2

PTPRF interacting protein alpha 2

involved_in

ISO

PMID:23751498

PMID:23751498

RGD:13702233

NCBI chr12:78,768,756...79,271,630
Ensembl chr12:81,879,812...82,376,917

PREPL

prolyl endopeptidase like

involved_in

IEA

GO_REF:0000107

NCBI chr2A:44,417,735...44,463,542
Ensembl chr2A:45,353,326...45,397,903

PRKCA

protein kinase C alpha

involved_in

ISO

(PMID:21658591)

PMID:21658591

NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903

PRKCB

protein kinase C beta

involved_in

IEA

GO_REF:0000107

NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203

protein kinase C gamma

involved_in

IEA

GO_REF:0000107

NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977

RAB3A, member RAS oncogene family

involved_in

ISO

PMID:28057568

PMID:28057568

RGD:14390053

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

RAB5A

RAB5A, member RAS oncogene family

involved_in

IEA

GO_REF:0000107

NCBI chr 3:19,866,110...19,903,701
Ensembl chr 3:20,197,067...20,234,579

regulating synaptic membrane exocytosis 1

involved_in

IEA

GO_REF:0000118

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

IEA

GO_REF:0000118

NCBI chr 8:100,156,403...100,894,128

regulating synaptic membrane exocytosis 3

acts_upstream_of_or_within
involved_in

ISO
IEA

PMID:20452978

PMID:20452978

GO_REF:0000118 RGD:8554325

NCBI chr 1:39,886,961...39,958,519
Ensembl chr 1:41,239,798...41,278,282

regulating synaptic membrane exocytosis 4

acts_upstream_of_or_within
involved_in

ISO
IEA

PMID:20452978

PMID:20452978

GO_REF:0000118 RGD:8554325

NCBI chr20:41,082,200...41,141,119
Ensembl chr20:42,180,764...42,234,847

SLC4A8

solute carrier family 4 member 8

involved_in

IEA

GO_REF:0000107

NCBI chr12:37,243,593...37,329,083
Ensembl chr12:38,134,574...38,214,036

SNAP29

synaptosome associated protein 29

involved_in

ISO

PMID:11707603

PMID:11707603

RGD:155230727

NCBI chr22:3,082,622...3,115,325
Ensembl chr22:19,572,618...19,605,931

SNAP associated protein

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095

STXBP5

syntaxin binding protein 5

involved_in

IEA

GO_REF:0000107

NCBI chr 6:145,006,696...145,192,467
Ensembl chr 6:149,719,064...149,902,662

STXBP5L

syntaxin binding protein 5L

involved_in

IEA

GO_REF:0000107

NCBI chr 3:118,022,061...118,529,311
Ensembl chr 3:124,932,110...125,434,515

SV2B

synaptic vesicle glycoprotein 2B

involved_in

ISO

(PMID:20620874)

PMID:20620874

NCBI chr15:69,793,642...69,989,339
Ensembl chr15:89,114,744...89,184,370

SV2C

synaptic vesicle glycoprotein 2C

involved_in

IEA

GO_REF:0000107

NCBI chr 5:38,969,056...39,222,300
Ensembl chr 5:39,566,207...39,836,852

SYN1

synapsin I

involved_in

ISO

(PMID:21441247)

PMID:21441247

NCBI chr X:40,007,777...40,055,801

synaptotagmin 1

involved_in

ISO

PMID:28057568

PMID:28057568

RGD:14390053

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

tumor protein p63 regulated 1 like

involved_in

ISO

PMID:26212709

PMID:26212709

RGD:13792549

NCBI chr 1:2,296,601...2,301,687

VPS18

VPS18 core subunit of CORVET and HOPS complexes

involved_in

IEA

GO_REF:0000107

NCBI chr15:19,836,707...19,846,231
Ensembl chr15:38,086,518...38,095,835

WNT7A

Wnt family member 7A

involved_in

IEA

GO_REF:0000107

NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386

regulation of synaptic vesicle fusion to presynaptic active zone membrane

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CPLX1

complexin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 4:889,037...930,046
Ensembl chr 4:819,833...858,953

complexin 2

involved_in

IEA

GO_REF:0000107

NCBI chr 5:171,144,671...171,233,028
Ensembl chr 5:178,115,947...178,128,595

CPLX3

complexin 3

involved_in

IEA

GO_REF:0000107

NCBI chr15:53,769,138...53,774,330
Ensembl chr15:73,386,826...73,391,991

glutamate ionotropic receptor kainate type subunit 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:38,886,108...38,956,938
Ensembl chr19:47,389,804...47,544,604

RAB3A, member RAS oncogene family

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:11359932)

PMID:11359932

GO_REF:0000107

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

regulation of synaptic vesicle priming

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BRSK1

BR serine/threonine kinase 1

involved_in

ISO

PMID:16630837

PMID:16630837

RGD:8553864

NCBI chr19:52,326,538...52,355,060
Ensembl chr19:61,021,493...61,045,659

NAPA

NSF attachment protein alpha

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:21040848)

Ensembl
TreeGrafter
MGI

PMID:21040848

GO_REF:0000107 GO_REF:0000118

NCBI chr19:44,479,871...44,507,315
Ensembl chr19:53,135,166...53,162,757

NAPB

NSF attachment protein beta

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:21040848)

Ensembl
TreeGrafter
MGI

PMID:21040848

GO_REF:0000107 GO_REF:0000118

NCBI chr20:23,316,153...23,363,142
Ensembl chr20:23,667,469...23,713,935

OSBPL2

oxysterol binding protein like 2

involved_in

IEA

GO_REF:0000107

NCBI chr20:58,605,041...58,660,782
Ensembl chr20:59,921,155...59,979,153

RAB3A, member RAS oncogene family

involved_in

ISO

PMID:21689256

PMID:21689256

RGD:14390056

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

syntaxin 1A

involved_in

IEA

GO_REF:0000107

Ensembl chr 7:80,852,495...80,862,255

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

syntaxin binding protein 1

involved_in

ISO

PMID:21689256

PMID:19255244 PMID:21689256

RGD:14390056 RGD:2311128

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

STXBP5

syntaxin binding protein 5

involved_in

IEA

GO_REF:0000107

NCBI chr 6:145,006,696...145,192,467
Ensembl chr 6:149,719,064...149,902,662

SYNGR3

synaptogyrin 3

involved_in

ISO

(PMID:31090538)

PMID:31090538

NCBI chr16:710,090...714,421
Ensembl chr16:2,078,645...2,083,100

synaptophysin

involved_in

IEA

GO_REF:0000107

NCBI chr X:41,487,538...41,500,039
Ensembl chr X:49,340,021...49,352,420

unc-13 homolog A

involved_in

ISO

PMID:21689256

PMID:21689256

RGD:14390056

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLITRK5

SLIT and NTRK like family member 5

involved_in

ISO

(PMID:26004511)

PMID:26004511

NCBI chr13:68,810,639...68,831,189
Ensembl chr13:87,980,905...87,983,781

synaptotagmin 4

involved_in

ISO

(PMID:19448629)

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CNRIP1

cannabinoid receptor interacting protein 1

involved_in

IEA

GO_REF:0000107

NCBI chr2A:68,332,179...68,368,033
Ensembl chr2A:69,456,924...69,492,716

FAAH

fatty acid amide hydrolase

involved_in

IEA

GO_REF:0000107

NCBI chr 1:45,697,173...45,716,629
Ensembl chr 1:47,053,436...47,072,283

neurexin 1

involved_in

ISO

(PMID:26213384)

PMID:26213384

NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277

p21 (RAC1) activated kinase 1

involved_in

ISO

(PMID:27296803)

PMID:27296803

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

regulation of translation at postsynapse, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYFIP1

cytoplasmic FMR1 interacting protein 1

involved_in

IEA

GO_REF:0000107

Ensembl chr15:20,462,811...20,573,684

EIF4E

eukaryotic translation initiation factor 4E

involved_in

ISO

(PMID:23263185)

PMID:23263185

NCBI chr 4:91,268,463...91,329,800
Ensembl chr 4:101,941,142...101,994,809

fragile X messenger ribonucleoprotein 1

involved_in

ISO

(PMID:12032354)

PMID:12032354

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

LOC100988043

eukaryotic initiation factor 4A-III

involved_in

ISO

PMID:17632064

PMID:17632064

RGD:10044262

NCBI chr17:74,221,793...74,233,738

regulation of translation at presynapse, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

fragile X messenger ribonucleoprotein 1

involved_in

IEA

GO_REF:0000118

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

FMR1 autosomal homolog 1

involved_in

IEA

GO_REF:0000118

NCBI chr 3:177,948,040...178,012,705

FXR2

FMR1 autosomal homolog 2

involved_in

IEA

GO_REF:0000118

NCBI chr17:7,622,855...7,646,340
Ensembl chr17:7,609,736...7,631,758

regulation of translation at synapse, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CPEB1

cytoplasmic polyadenylation element binding protein 1

involved_in

ISO

(PMID:18716208)

PMID:18716208

NCBI chr15:62,949,264...63,053,994
Ensembl chr15:80,443,096...80,526,948

CPEB2

cytoplasmic polyadenylation element binding protein 2

involved_in

ISO

(PMID:29141213)

PMID:29141213

NCBI chr 4:9,431,573...9,499,036

MTOR

mechanistic target of rapamycin kinase

involved_in

ISO

PMID:15525761

PMID:15525761

RGD:2307416

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

retrograde trans-synaptic signaling by endocannabinoid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cannabinoid receptor 1

involved_in

ISO

(PMID:11516401)

PMID:11516401

NCBI chr 6:86,017,141...86,044,889

DAGLA

diacylglycerol lipase alpha

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr11:56,979,558...57,046,589
Ensembl chr11:60,378,493...60,407,095

FABP5

fatty acid binding protein 5

involved_in

ISO

(PMID:29531087)

PMID:29531087

NCBI chr 8:77,803,369...77,807,630
Ensembl chr 8:79,426,684...79,430,879

retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GUCY1A1

guanylate cyclase 1 soluble subunit alpha 1

involved_in

IEA

GO_REF:0000107

NCBI chr 4:148,032,167...148,102,757
Ensembl chr 4:159,850,107...159,913,338

retrograde trans-synaptic signaling by trans-synaptic protein complex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CADM1

cell adhesion molecule 1

involved_in

ISO

(PMID:23209303)

PMID:23209303

NCBI chr11:110,008,314...110,347,876
Ensembl chr11:113,950,291...114,280,324

DAG1

dystroglycan 1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:49,396,180...49,464,689
Ensembl chr 3:50,640,615...50,703,852

FARP1

FERM, ARH/RhoGEF and pleckstrin domain protein 1

involved_in

ISO

PMID:23209303

PMID:23209303

RGD:8554251

NCBI chr13:79,300,995...79,615,649
Ensembl chr13:98,522,235...98,761,085

TENM2

teneurin transmembrane protein 2

involved_in

IEA

GO_REF:0000107

NCBI chr 5:162,346,710...163,627,371
Ensembl chr 5:169,420,480...170,392,581

rhythmic excitation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CHAT

choline O-acetyltransferase

acts_upstream_of_or_within

ISO

(PMID:15820692)

PMID:15820692

NCBI chr10:44,574,925...44,629,618

EDN1

endothelin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

rhythmic synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

ISO

(PMID:16474392)

PMID:16474392

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

CACNA2D2

calcium voltage-gated channel auxiliary subunit alpha2delta 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:50,288,926...50,430,152
Ensembl chr 3:51,526,075...51,640,406

neuroligin 3

involved_in

ISO

PMID:19406211

PMID:19406211

RGD:8554851

NCBI chr X:60,413,098...60,439,359
Ensembl chr X:70,469,764...70,496,526

phosphatase and tensin homolog

involved_in

ISO

(PMID:17706614)

PMID:17706614

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

serotonin secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

XBP1

X-box binding protein 1

ISO

PMID:16889758

RGD:2326003

NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943

short-term synaptic potentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

chordin

involved_in

ISO

(PMID:17634368)

NCBI chr 3:181,417,140...181,460,236
Ensembl chr 3:189,898,856...189,908,573

NCSTN

nicastrin

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911

noggin

involved_in

IEA

GO_REF:0000107

NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092

SYT7

synaptotagmin 7

involved_in

ISO

(PMID:26738595)
(PMID:24569478)

PMID:24569478 PMID:26738595

NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375

spontaneous exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein kinase cAMP-activated catalytic subunit alpha

involved_in

ISO

PMID:17190793

PMID:17190793

RGD:10047304

NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205

synaptotagmin 12

involved_in

ISO

PMID:17190793

GO_Central

PMID:17190793

RGD:10047304

NCBI chr11:62,383,485...62,412,451
Ensembl chr11:65,709,808...65,733,010

spontaneous neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

double C2 domain alpha

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

Ensembl chr16:30,378,922...30,384,142

DOC2B

double C2 domain beta

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:21521611)

PMID:21521611

GO_REF:0000118

NCBI chr17:19,854...58,336

regulating synaptic membrane exocytosis 1

involved_in

ISO

(PMID:21262469)

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

ISO

(PMID:21262469)

NCBI chr 8:100,156,403...100,894,128

RPH3A

rabphilin 3A

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr12:110,393,495...110,504,099
Ensembl chr12:113,815,437...113,886,701

RPH3AL

rabphilin 3A like (without C2 domains)

involved_in

IEA

GO_REF:0000118

NCBI chr17:90,816...293,651
Ensembl chr17:146,155...283,278

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

synaptotagmin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

unc-13 homolog B

involved_in

ISO

PMID:21262469

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

spontaneous synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBLN2

cerebellin 2 precursor

involved_in

ISO

(PMID:30287486)

PMID:30287486

NCBI chr18:65,906,154...66,010,195

NSG1

neuronal vesicle trafficking associated 1

involved_in

ISO

PMID:15911354

PMID:15911354

RGD:9850096

Ensembl chr 4:4,467,234...4,496,088

synaptic transmission involved in micturition

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cholinergic receptor nicotinic alpha 3 subunit

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:10771006)

PMID:10771006

GO_REF:0000107

NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044

cholinergic receptor nicotinic beta 2 subunit

acts_upstream_of_or_within

ISO

(PMID:10531434)

PMID:10531434

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

CHRNB4

cholinergic receptor nicotinic beta 4 subunit

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:10531434)
(PMID:10771006)

PMID:10531434 PMID:10771006

GO_REF:0000107

NCBI chr15:57,552,697...57,570,828
Ensembl chr15:76,515,455...76,532,712

neuronal acetylcholine receptor subunit alpha-7

involved_in

ISO

PMID:22250215

PMID:22250215

RGD:597976624

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

synaptic transmission, cholinergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A2a receptor

ISO

PMID:15297571

RGD:1625662

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

ANXA9

annexin A9

involved_in

IEA

GO_REF:0000108

NCBI chr 1:126,331,255...126,345,056
Ensembl chr 1:129,979,652...129,993,456

CHRM3

cholinergic receptor muscarinic 3

acts_upstream_of_or_within

ISO

(PMID:10944224)

PMID:10944224

NCBI chr 1:214,931,514...215,452,739

CHRNA1

cholinergic receptor nicotinic alpha 1 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr2B:62,022,498...62,039,370
Ensembl chr2B:179,476,677...179,504,763

CHRNA10

cholinergic receptor nicotinic alpha 10 subunit

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:3,543,450...3,552,036
Ensembl chr11:3,651,580...3,656,780

cholinergic receptor nicotinic alpha 2 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr 8:26,729,767...26,749,277
Ensembl chr 8:23,932,846...23,952,377

cholinergic receptor nicotinic alpha 3 subunit

involved_in
acts_upstream_of_or_within

IEA
ISO

(PMID:16162937)

GOC
MGI

PMID:16162937

GO_REF:0000108

NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044

PMID:11226318 PMID:11906696 PMID:15026122

cholinergic receptor nicotinic alpha 4 subunit

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:11906696)
(PMID:11226318)

RGD
Ensembl
MGI

GO_REF:0000107 RGD:1358635

NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005

cholinergic receptor nicotinic alpha 5 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr15:57,493,730...57,530,463
Ensembl chr15:76,455,165...76,486,376

CHRNB1

cholinergic receptor nicotinic beta 1 subunit

involved_in

IEA

GO_REF:0000107

NCBI chr17:7,479,056...7,490,314
Ensembl chr17:7,465,229...7,476,099

cholinergic receptor nicotinic beta 2 subunit

involved_in

ISO
IEA

PMID:12754307

GO_REF:0000107 RGD:1358637

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

CHRNB4

cholinergic receptor nicotinic beta 4 subunit

involved_in

IEA

GO_REF:0000108

NCBI chr15:57,552,697...57,570,828
Ensembl chr15:76,515,455...76,532,712

DMD

dystrophin

acts_upstream_of_positive_effect

IEA

GO_REF:0000107

NCBI chr X:23,728,650...26,338,849
Ensembl chr X:31,282,415...33,492,733

PMID:9364063 PMID:15044058 PMID:17510177 PMID:20164328

neuronal acetylcholine receptor subunit alpha-7

involved_in
acts_upstream_of_or_within

ISO

(PMID:20164328)
PMID:17510177
(PMID:9364063)

RGD
ARUK-UCL
UniProt
MGI

RGD:1600975 RGD:596936198

NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194

LYNX1

Ly6/neurotoxin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 8:139,483,627...139,490,722
Ensembl chr 8:142,526,506...142,533,707

LYPD1

LY6/PLAUR domain containing 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:27,170,199...27,201,789
Ensembl chr2B:136,738,362...136,769,150

RAPSN

receptor associated protein of the synapse

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr11:47,387,324...47,398,579
Ensembl chr11:47,940,530...47,951,667

RIC3

RIC3 acetylcholine receptor chaperone

acts_upstream_of_or_within
involved_in

ISO
IEA

PMID:18420419

PMID:18420419

GO_REF:0000118 RGD:2317082

NCBI chr11:8,210,061...8,287,211
Ensembl chr11:7,969,236...8,032,884

SLC5A7

solute carrier family 5 member 7

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:15173594)
(PMID:16162937)

PMID:15173594 PMID:16162937

GO_REF:0000118

NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860

synaptic transmission, dopaminergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine A2a receptor

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

APH1B

aph-1 homolog B, gamma-secretase subunit

acts_upstream_of_or_within

ISO

(PMID:18626010)

PMID:18626010

NCBI chr15:42,224,593...42,256,202
Ensembl chr15:60,520,031...60,551,599

cyclin dependent kinase 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

COMT

catechol-O-methyltransferase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387

CRH

corticotropin releasing hormone

involved_in

IEA

GO_REF:0000107

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

CRHBP

corticotropin releasing hormone binding protein

involved_in

IEA

GO_REF:0000107

NCBI chr 5:38,327,305...38,343,901
Ensembl chr 5:38,845,925...38,869,549

dopamine receptor D1

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:16908842)

MGI
GOC

PMID:16908842

GO_REF:0000108

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

dopamine receptor D2

involved_in

IEA

GO_REF:0000108

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

DRD3

dopamine receptor D3

involved_in

IEA

GO_REF:0000108

NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403

dopamine receptor D4

involved_in

ISO
IEA

RGD
GOC

PMID:15476261

GO_REF:0000108 RGD:1600954

NCBI chr11:640,401...646,775

DRD5

dopamine receptor D5

involved_in

IEA

GO_REF:0000108

NCBI chr 4:4,189,536...4,193,144
Ensembl chr 4:9,509,094...9,510,527

HTR2B

5-hydroxytryptamine receptor 2B

involved_in

IEA

GO_REF:0000108

NCBI chr2B:118,362,719...118,381,253
Ensembl chr2B:237,153,709...237,170,591

PARK7

Parkinsonism associated deglycase

acts_upstream_of_or_within

ISO

(PMID:15799973)

PMID:15799973

NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271

parkin RBR E3 ubiquitin protein ligase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

RASD2

RASD family member 2

involved_in

ISO

(PMID:18035555), (PMID:18845937)

PMID:18035555 PMID:18845937

NCBI chr22:16,549,140...16,562,716
Ensembl chr22:34,394,233...34,403,090

synuclein alpha

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

tyrosine hydroxylase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433

synaptic transmission, GABAergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ALDH5A1

aldehyde dehydrogenase 5 family member A1

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr 6:24,332,093...24,370,764
Ensembl chr 6:24,665,026...24,705,151

calcium voltage-gated channel subunit alpha1 A

NOT|acts_upstream_of_or_within

ISO

(PMID:10322048)

PMID:10322048

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

CACNB4

calcium voltage-gated channel auxiliary subunit beta 4

NOT|acts_upstream_of_or_within

ISO

(PMID:10322048)

PMID:10322048

NCBI chr2B:39,137,777...39,399,007
Ensembl chr2B:156,379,469...156,639,328

CLCN3

chloride voltage-gated channel 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:161,838,061...161,943,072
Ensembl chr 4:173,925,474...174,011,681

CLSTN3

calsyntenin 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:7,260,361...7,288,903
Ensembl chr12:7,175,951...7,204,526

EZH2

enhancer of zeste 2 polycomb repressive complex 2 subunit

ISO

PMID:27690696

RGD:126781724

NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726

GABRA1

gamma-aminobutyric acid type A receptor subunit alpha1

involved_in

IEA

GO_REF:0000107

NCBI chr 5:157,234,725...157,287,475
Ensembl chr 5:163,928,392...163,981,117

GABRA6

gamma-aminobutyric acid type A receptor subunit alpha6

ISO

PMID:16554486

RGD:1626493

NCBI chr 5:157,072,915...157,089,994
Ensembl chr 5:163,767,304...163,784,331

GABRB2

gamma-aminobutyric acid type A receptor subunit beta2

involved_in

ISO

PMID:12930820

NCBI chr 5:156,678,750...156,937,614
Ensembl chr 5:163,374,346...163,632,301

GABRB3

gamma-aminobutyric acid type A receptor subunit beta3

involved_in

ISO
IEA

PMID:12930820 PMID:14993607

PMID:12356876

GO_REF:0000107 RGD:727440

NCBI chr15:3,129,481...3,357,495
Ensembl chr15:23,981,359...24,058,357

GABRG2

gamma-aminobutyric acid type A receptor subunit gamma2

involved_in

ISO

PMID:12930820
(PMID:14993607)

BHF-UCL
UniProt

NCBI chr 5:157,436,113...157,529,586
Ensembl chr 5:164,068,122...164,222,179

glutamate ionotropic receptor kainate type subunit 1

acts_upstream_of

ISO

(PMID:17245443)

PMID:17245443

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

HAPLN4

hyaluronan and proteoglycan link protein 4

involved_in

IEA

GO_REF:0000107

NCBI chr19:18,694,303...18,701,553
Ensembl chr19:19,699,817...19,703,735

neuroligin 2

acts_upstream_of_or_within

ISO

(PMID:29107521)

PMID:29107521

NCBI chr17:7,438,853...7,454,014

PRKCE

protein kinase C epsilon

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313

RAC1

Rac family small GTPase 1

acts_upstream_of_or_within

ISO

(PMID:23258346)

PMID:23258346

NCBI chr 7:7,039,379...7,068,866

RAC3

Rac family small GTPase 3

acts_upstream_of_or_within

ISO

(PMID:23258346)

PMID:23258346

NCBI chr17:76,436,264...76,439,492
Ensembl chr17:82,133,217...82,143,623

SLITRK3

SLIT and NTRK like family member 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 3:162,207,530...162,223,830
Ensembl chr 3:170,265,342...170,268,275

TPBG

trophoblast glycoprotein

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:80,265,172...80,273,022
Ensembl chr 6:83,530,571...83,531,915

VPS54

VPS54 subunit of GARP complex

involved_in

IEA

GO_REF:0000107

NCBI chr2A:63,959,930...64,087,102
Ensembl chr2A:65,086,374...65,176,634

synaptic transmission, glutamatergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABTB3

ankyrin repeat and BTB domain containing 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:104,888,102...105,229,573

adenosine A2a receptor

ISO

PMID:16644907

RGD:1625443

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

adrenoceptor beta 2

ISO

PMID:17175110

RGD:5129150

NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892

ALS2

alsin Rho guanine nucleotide exchange factor ALS2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:88,954,167...89,034,764
Ensembl chr2B:207,108,952...207,189,623

APH1B

aph-1 homolog B, gamma-secretase subunit

acts_upstream_of_or_within

ISO

(PMID:18626010)

PMID:18626010

NCBI chr15:42,224,593...42,256,202
Ensembl chr15:60,520,031...60,551,599

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

ISO

(PMID:10322048)
(PMID:14973254)

PMID:10322048 PMID:14973254

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

CACNB4

calcium voltage-gated channel auxiliary subunit beta 4

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr2B:39,137,777...39,399,007
Ensembl chr2B:156,379,469...156,639,328

CDH8

cadherin 8

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr16:41,935,706...42,326,055
Ensembl chr16:61,054,214...61,437,569

cyclin dependent kinase 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

CLCN3

chloride voltage-gated channel 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:161,838,061...161,943,072
Ensembl chr 4:173,925,474...174,011,681

CLSTN3

calsyntenin 3

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:7,260,361...7,288,903
Ensembl chr12:7,175,951...7,204,526

CNIH2

cornichon family AMPA receptor auxiliary protein 2

acts_upstream_of_or_within

ISO

PMID:19265014

PMID:19265014

RGD:8554136

NCBI chr11:61,643,633...61,649,646
Ensembl chr11:64,969,447...64,975,156

CNIH3

cornichon family AMPA receptor auxiliary protein 3

acts_upstream_of_or_within

ISO

PMID:19265014

PMID:19265014

RGD:8554136

NCBI chr 1:199,903,319...200,243,433
Ensembl chr 1:205,092,073...205,216,665

DCDC2

doublecortin domain containing 2

acts_upstream_of_or_within

ISO

(PMID:24094509), (PMID:26250775)

PMID:24094509 PMID:26250775

NCBI chr 6:24,001,971...24,186,530
Ensembl chr 6:24,337,188...24,520,082

dopamine receptor D1

acts_upstream_of

ISO

(PMID:8795639)

PMID:8795639

NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257

DSCAM

DS cell adhesion molecule

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr21:26,366,295...27,192,617
Ensembl chr21:39,699,077...40,524,164

EXT1

exostosin glycosyltransferase 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 8:114,489,325...114,803,763
Ensembl chr 8:117,011,919...117,324,851

GRID2

glutamate ionotropic receptor delta type subunit 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 4:84,663,030...86,170,778
Ensembl chr 4:95,339,460...96,807,748

glutamate ionotropic receptor kainate type subunit 1

acts_upstream_of_or_within

ISO

(PMID:15509753)
(PMID:15928066)

PMID:15509753 PMID:15928066

NCBI chr21:15,976,931...16,357,578
Ensembl chr21:29,364,269...29,743,379

glutamate ionotropic receptor kainate type subunit 2

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:98,720,430...99,903,582
Ensembl chr 6:103,334,707...103,783,092

glutamate ionotropic receptor kainate type subunit 5

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr19:38,886,108...38,956,938
Ensembl chr19:47,389,804...47,544,604

glutamate ionotropic receptor NMDA type subunit 1

acts_upstream_of_or_within

ISO

(PMID:10963597)
(PMID:8313466)

PMID:8313466 PMID:10963597

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

glutamate ionotropic receptor NMDA type subunit 2D

ISO

PMID:15107472

RGD:1642397

NCBI chr19:45,392,258...45,447,004

glutamate metabotropic receptor 8

involved_in

ISO

PMID:15275822

PMID:15275822

RGD:6484726

NCBI chr 7:118,430,086...119,249,147

NAPA

NSF attachment protein alpha

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr19:44,479,871...44,507,315
Ensembl chr19:53,135,166...53,162,757

NAPB

NSF attachment protein beta

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr20:23,316,153...23,363,142
Ensembl chr20:23,667,469...23,713,935

NPS

neuropeptide S

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr10:124,135,616...124,139,845
Ensembl chr10:128,384,897...128,388,217

NR3C1

nuclear receptor subfamily 3 group C member 1

involved_in

IEA

GO_REF:0000107

NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269

P2RX1

purinergic receptor P2X 1

ISO

NCBI chr17:3,944,636...3,965,260
Ensembl chr17:3,935,982...3,956,595

PLAT

plasminogen activator, tissue type

ISO

PMID:15496678

RGD:1581924

NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779

parkin RBR E3 ubiquitin protein ligase

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

SHC3

SHC adaptor protein 3

acts_upstream_of_or_within

ISO

(PMID:15716419)

PMID:15716419

NCBI chr 9:60,095,067...60,269,949
Ensembl chr 9:88,148,449...88,311,146

SLC17A6

solute carrier family 17 member 6

involved_in

IEA

GO_REF:0000118

NCBI chr11:22,350,537...22,392,009
Ensembl chr11:22,258,011...22,301,944

SLC17A7

solute carrier family 17 member 7

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr19:46,443,076...46,455,195
Ensembl chr19:55,365,811...55,377,438

SLC17A8

solute carrier family 17 member 8

involved_in

IEA

GO_REF:0000118

NCBI chr12:97,935,177...98,001,240
Ensembl chr12:101,342,113...101,405,844

tenascin R

acts_upstream_of

IEA

GO_REF:0000107

NCBI chr 1:150,826,892...151,257,301
Ensembl chr 1:154,532,582...154,615,538

unc-13 homolog A

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:11792326)
(PMID:11832228)

PMID:11792326 PMID:11832228

GO_REF:0000118

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

unc-13 homolog B

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:11792326)
(PMID:11832228)

PMID:11792326 PMID:11832228

GO_REF:0000118

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

VPS54

VPS54 subunit of GARP complex

involved_in

IEA

GO_REF:0000107

NCBI chr2A:63,959,930...64,087,102
Ensembl chr2A:65,086,374...65,176,634

ZZEF1

zinc finger ZZ-type and EF-hand domain containing 1

acts_upstream_of_or_within

ISO

(PMID:25709106)

PMID:25709106

NCBI chr17:4,059,659...4,197,386
Ensembl chr17:4,054,952...4,188,735

synaptic transmission, glycinergic

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PMID:15574743 PMID:24801766

glycine receptor alpha 1

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:24801766)

RGD
UniProt
Ensembl

GO_REF:0000107 RGD:1598572

NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567

GLRB

glycine receptor beta

acts_upstream_of_or_within

ISO
IEA

PMID:15574743

GO_REF:0000107 RGD:1598572

NCBI chr 4:149,422,654...149,518,669
Ensembl chr 4:161,236,610...161,333,035

SLC6A5

solute carrier family 6 member 5

involved_in

IEA

GO_REF:0000107

NCBI chr11:20,627,557...20,691,347
Ensembl chr11:20,538,054...20,592,893

synaptic vesicle docking

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CTBP2

C-terminal binding protein 2

involved_in

ISO

(PMID:26929012)

PMID:26929012

NCBI chr10:121,550,194...121,722,828
Ensembl chr10:125,814,926...125,901,248

PTPRF interacting protein alpha 3

involved_in

IEA

GO_REF:0000107

NCBI chr19:46,130,396...46,162,065
Ensembl chr19:55,056,824...55,089,124

regulating synaptic membrane exocytosis 1

involved_in

ISO

(PMID:21241895)

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

ISO

(PMID:21241895)

NCBI chr 8:100,156,403...100,894,128

syntaxin 1A

involved_in

ISO

PMID:1321498

PMID:1321498

RGD:8553325

Ensembl chr 7:80,852,495...80,862,255

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

STX4

syntaxin 4

ISO

PMID:7690687

RGD:68313

NCBI chr16:23,917,576...23,933,884
Ensembl chr16:31,400,915...31,411,364

SYDE1

synapse defective Rho GTPase homolog 1

acts_upstream_of_or_within

ISO

(PMID:23791195)

PMID:23791195

NCBI chr19:14,640,493...14,648,080
Ensembl chr19:15,625,096...15,631,600

tumor protein p63 regulated 1 like

acts_upstream_of_or_within

ISO

(PMID:33431696)

PMID:33431696

NCBI chr 1:2,296,601...2,301,687

unc-13 homolog A

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:19558619)

PMID:19558619

GO_REF:0000118

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

unc-13 homolog B

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:19558619)

PMID:19558619

GO_REF:0000118

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

VAMP2

vesicle associated membrane protein 2

involved_in

ISO

(PMID:25374362)

PMID:25374362

NCBI chr17:43,495,464...43,499,348
Ensembl chr17:48,228,253...48,231,948

synaptic vesicle exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B-Raf proto-oncogene, serine/threonine kinase

acts_upstream_of

ISO

(PMID:23616533)

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

CADPS

calcium dependent secretion activator

involved_in

IEA

GO_REF:0000002

NCBI chr 3:62,321,496...62,797,298

CADPS2

calcium dependent secretion activator 2

involved_in

IEA

GO_REF:0000002

NCBI chr 7:114,328,933...114,896,388
Ensembl chr 7:127,014,772...127,579,249

CPLX1

complexin 1

involved_in

ISO
IEA

RGD
TreeGrafter
Ensembl

PMID:11751907

GO_REF:0000107 GO_REF:0000118 RGD:727333

NCBI chr 4:889,037...930,046
Ensembl chr 4:819,833...858,953

complexin 2

involved_in

ISO
IEA

PMID:11751907

GO_REF:0000118 RGD:727333

NCBI chr 5:171,144,671...171,233,028
Ensembl chr 5:178,115,947...178,128,595

CPLX3

complexin 3

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr15:53,769,138...53,774,330
Ensembl chr15:73,386,826...73,391,991

CPLX4

complexin 4

involved_in

IEA

GO_REF:0000118

NCBI chr18:52,691,095...52,713,697
Ensembl chr18:55,998,958...56,040,108

double C2 domain alpha

ISO

PMID:10651871

RGD:1357914

Ensembl chr16:30,378,922...30,384,142

dishevelled segment polarity protein 1

acts_upstream_of_positive_effect

IEA

PMID:17055430 PMID:18287496 PMID:25609709

GO_REF:0000107

NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008

OTOF

otoferlin

acts_upstream_of_or_within
involved_in

ISO

(PMID:25609709)
(PMID:17055430), (PMID:18287496)

MGI
UniProt
SynGO

NCBI chr2A:26,454,010...26,555,642
Ensembl chr2A:26,546,959...26,647,278

P2RX7

purinergic receptor P2X 7

acts_upstream_of_or_within

ISO

(PMID:15713258)

PMID:15713258

NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068

PTPRF interacting protein alpha 3

involved_in

IEA

GO_REF:0000107

NCBI chr19:46,130,396...46,162,065
Ensembl chr19:55,056,824...55,089,124

RAB3A, member RAS oncogene family

acts_upstream_of_or_within
involved_in

IEA
ISO

PMID:16141272

Ensembl
ParkinsonsUK-UCL

PMID:16141272

GO_REF:0000107 RGD:8693376

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

RAP1A

RAP1A, member of RAS oncogene family

acts_upstream_of

ISO

(PMID:23616533)

NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813

reelin

involved_in

ISO

PMID:24210904

PMID:24210904

RGD:405650351

NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037

synaptosome associated protein 25

involved_in

IEA

GO_REF:0000107

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SNAP associated protein

involved_in
acts_upstream_of_or_within

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095

synuclein alpha

involved_in

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

SPTBN2

spectrin beta, non-erythrocytic 2

involved_in

ISO

PMID:9826670

PMID:9826670

RGD:8553838

NCBI chr11:62,042,617...62,086,634
Ensembl chr11:65,365,588...65,409,207

syntaxin 1A

involved_in

IEA

GO_REF:0000107

Ensembl chr 7:80,852,495...80,862,255

syntaxin 1B

involved_in

IEA

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

synaptotagmin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

SYT10

synaptotagmin 10

NOT|involved_in

ISO

(PMID:21496647)

PMID:21496647

NCBI chr12:52,761,294...52,830,221
Ensembl chr12:55,364,714...55,429,298

TRIM9

tripartite motif containing 9

ISO

PMID:11524423

RGD:631246

NCBI chr14:31,577,859...31,844,298
Ensembl chr14:49,863,433...49,986,212

unc-13 homolog A

involved_in

ISO

(PMID:10440375)

PMID:10440375

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

unc-13 homolog B

involved_in

ISO

(PMID:19700493)

PMID:19700493

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

unc-13 homolog C

involved_in

ISO

(PMID:11150314)

PMID:1331807 PMID:11691998 PMID:15475946

PMID:11150314

NCBI chr15:32,914,784...33,563,610

VAMP2

vesicle associated membrane protein 2

involved_in
acts_upstream_of_or_within

ISO

PMID:1331807
(PMID:15475946)
(PMID:11691998)

SynGO
UniProt
MGI

RGD:13702243

NCBI chr17:43,495,464...43,499,348
Ensembl chr17:48,228,253...48,231,948

VAMP7

vesicle associated membrane protein 7

involved_in

ISO

PMID:24210904

PMID:24210904

RGD:405650351

NCBI chr X:145,362,432...145,425,097
Ensembl chr X:155,257,185...155,320,215

synaptic vesicle fusion to presynaptic active zone membrane

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PRRT2

proline rich transmembrane protein 2

involved_in

IEA

GO_REF:0000107

Ensembl chr16:30,183,352...30,187,862

SNAP23

synaptosome associated protein 23

involved_in

IEA

GO_REF:0000118

NCBI chr15:21,456,247...21,494,340
Ensembl chr15:39,612,445...39,650,759

synaptosome associated protein 25

involved_in

IEA

GO_REF:0000118

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SNAP29

synaptosome associated protein 29

involved_in

IEA

GO_REF:0000118

NCBI chr22:3,082,622...3,115,325
Ensembl chr22:19,572,618...19,605,931

SNAP47

synaptosome associated protein 47

involved_in

IEA

GO_REF:0000118

NCBI chr 1:203,128,827...203,181,521
Ensembl chr 1:208,115,118...208,161,139

SNAP associated protein

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095

STX11

syntaxin 11

involved_in

IEA

GO_REF:0000118

NCBI chr 6:141,924,656...141,974,579
Ensembl chr 6:146,688,670...146,689,533

STX19

syntaxin 19

involved_in

IEA

GO_REF:0000118

NCBI chr 3:91,079,351...91,093,741
Ensembl chr 3:97,759,213...97,760,097

syntaxin 1B

involved_in

IEA

GO_REF:0000107 GO_REF:0000118

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

STX2

syntaxin 2

involved_in

IEA

PMID:18022372 PMID:21040848

GO_REF:0000118

NCBI chr12:128,416,793...128,464,452
Ensembl chr12:132,614,793...132,650,559

synaptic vesicle priming

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CADPS

calcium dependent secretion activator

acts_upstream_of_or_within
involved_in

ISO

(PMID:21040848)
(PMID:18022372)

MGI
SynGO

NCBI chr 3:62,321,496...62,797,298

CADPS2

calcium dependent secretion activator 2

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:21040848)

MGI
Ensembl

PMID:21040848

GO_REF:0000107

NCBI chr 7:114,328,933...114,896,388
Ensembl chr 7:127,014,772...127,579,249

EFR3A

EFR3 homolog A

involved_in

IEA

GO_REF:0000107

NCBI chr 8:128,553,529...128,662,782
Ensembl chr 8:131,530,751...131,639,637

ELKS/RAB6-interacting/CAST family member 1

involved_in

ISO

(PMID:27253063)

PMID:27253063

NCBI chr12:1,066,034...1,597,562
Ensembl chr12:1,027,967...1,545,431

ELKS/RAB6-interacting/CAST family member 2

involved_in

IEA

GO_REF:0000107

NCBI chr 3:55,438,875...56,417,072
Ensembl chr 3:56,836,941...57,599,248

NAPA

NSF attachment protein alpha

involved_in

IEA

GO_REF:0000107

NCBI chr19:44,479,871...44,507,315
Ensembl chr19:53,135,166...53,162,757

OTOF

otoferlin

involved_in

IEA

GO_REF:0000118

NCBI chr2A:26,454,010...26,555,642
Ensembl chr2A:26,546,959...26,647,278

regulating synaptic membrane exocytosis 1

involved_in

ISO

(PMID:21262469), (PMID:22753485)

PMID:21262469 PMID:22753485

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

regulating synaptic membrane exocytosis 2

involved_in

ISO

(PMID:21262469), (PMID:22753485)

PMID:21262469 PMID:22753485

NCBI chr 8:100,156,403...100,894,128

RPH3A

rabphilin 3A

involved_in

IEA

GO_REF:0000107

NCBI chr12:110,393,495...110,504,099
Ensembl chr12:113,815,437...113,886,701

SNAP23

synaptosome associated protein 23

involved_in

IEA

GO_REF:0000118

NCBI chr15:21,456,247...21,494,340
Ensembl chr15:39,612,445...39,650,759

synaptosome associated protein 25

involved_in

IEA

GO_REF:0000118

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SNAP29

synaptosome associated protein 29

involved_in

IEA

GO_REF:0000118

NCBI chr22:3,082,622...3,115,325
Ensembl chr22:19,572,618...19,605,931

SNAP47

synaptosome associated protein 47

involved_in

IEA

GO_REF:0000118

NCBI chr 1:203,128,827...203,181,521
Ensembl chr 1:208,115,118...208,161,139

synuclein alpha

involved_in

IEA

GO_REF:0000107

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

syntaxin binding protein 1

involved_in

IEA

GO_REF:0000107

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

SV2A

synaptic vesicle glycoprotein 2A

involved_in

IEA

GO_REF:0000107

NCBI chr 1:125,247,429...125,262,041
Ensembl chr 1:128,904,151...128,918,829

SYNJ1

synaptojanin 1

acts_upstream_of_or_within

ISO

(PMID:12481038)

PMID:12481038

NCBI chr21:18,990,526...19,088,839
Ensembl chr21:32,368,949...32,466,994

unc-13 homolog A

involved_in

ISO
IEA

PMID:21499244

GO_REF:0000118 RGD:5686389

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

unc-13 homolog B

acts_upstream_of_or_within
involved_in

ISO
IEA

(PMID:12070347)

PMID:12070347

GO_REF:0000118

NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894

unc-13 homolog C

involved_in

ISO

PMID:22966208

PMID:22966208

RGD:11535109

NCBI chr15:32,914,784...33,563,610

synaptic vesicle targeting

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

neuroligin 1

involved_in

IEA

GO_REF:0000107

NCBI chr 3:170,416,885...171,333,094
Ensembl chr 3:178,810,253...179,503,756

PSEN1

presenilin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876

SCRIB

scribble planar cell polarity protein

involved_in

IEA

GO_REF:0000107

NCBI chr 8:140,544,797...140,571,078
Ensembl chr 8:143,557,722...143,582,353

synchronous neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 1

acts_upstream_of_or_within

IEA

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

trans-synaptic signaling by BDNF

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

methyl-CpG binding protein 2

acts_upstream_of

ISO

(PMID:17050729)

PMID:17050729

NCBI chr X:143,571,864...143,647,192
Ensembl chr X:153,465,204...153,527,854

trans-synaptic signaling by BDNF, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

brain derived neurotrophic factor

involved_in

ISO

(PMID:19448629)

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

LOC100982214

plasminogen

involved_in

ISO

(PMID:15486301)

PMID:15486301

NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777

neurotrophic receptor tyrosine kinase 2

involved_in

IEA

GO_REF:0000107

NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678

PLAT

plasminogen activator, tissue type

involved_in

IEA

GO_REF:0000107

NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779

trans-synaptic signaling by endocannabinoid, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CNR2

cannabinoid receptor 2

involved_in

IEA

GO_REF:0000107

NCBI chr 1:23,066,153...23,108,065
Ensembl chr 1:24,050,008...24,051,090

F2R

coagulation factor II thrombin receptor

involved_in

IEA

GO_REF:0000107

NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,110,170...39,129,688
Ensembl chr 5:39,110,170...39,129,688

trans-synaptic signaling by neuropeptide, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

neurotrophic receptor tyrosine kinase 2

involved_in

IEA

GO_REF:0000118

NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678

trans-synaptic signaling by trans-synaptic complex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL1RAP

interleukin 1 receptor accessory protein

involved_in

IEA

GO_REF:0000107

NCBI chr 3:187,535,880...187,680,628
Ensembl chr 3:196,089,208...196,231,379

IL1RAPL1

interleukin 1 receptor accessory protein like 1

involved_in

IEA

GO_REF:0000107

NCBI chr X:21,180,693...22,548,122
Ensembl chr X:28,950,521...30,109,286

PTPRD

protein tyrosine phosphatase receptor type D

involved_in

IEA

GO_REF:0000107

NCBI chr 9:8,113,171...10,420,732
Ensembl chr 9:8,288,569...8,831,227

trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EFNB3

ephrin B3

involved_in

IEA

GO_REF:0000107

NCBI chr17:7,737,297...7,743,732
Ensembl chr17:7,724,983...7,731,270

neuroplastin

involved_in

ISO

PMID:10759566

PMID:10759566

RGD:8553916

NCBI chr15:52,470,545...52,544,046
Ensembl chr15:71,229,992...71,269,579

trans-synaptic signaling, modulating synaptic transmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBLN1

cerebellin 1 precursor

involved_in

IEA

GO_REF:0000107

NCBI chr16:29,538,723...29,542,625
Ensembl chr16:48,427,645...48,430,512

CBLN2

cerebellin 2 precursor

involved_in

ISO

(PMID:36205393)
(PMID:29784783), (PMID:36205393)

PMID:29784783 PMID:36205393

NCBI chr18:65,906,154...66,010,195

CBLN4

cerebellin 4 precursor

involved_in

IEA

GO_REF:0000107

NCBI chr20:52,330,743...52,339,896
Ensembl chr20:53,548,083...53,557,294

IGSF21

immunoglobin superfamily member 21

involved_in

IEA

GO_REF:0000107

NCBI chr 1:17,063,522...17,336,389
Ensembl chr 1:18,116,451...18,387,611

NEO1

neogenin 1

involved_in

IEA

GO_REF:0000107

NCBI chr15:51,968,238...52,221,116
Ensembl chr15:70,789,035...70,977,178

neurexin 1

involved_in

ISO

(PMID:36205393)

PMID:36205393

NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277

neurexin 3

involved_in

ISO

(PMID:36205393)