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ONTOLOGY REPORT - ANNOTATIONS

Term:voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
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Accession:GO:0099508 term browser browse the term
Definition:Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.
Synonyms:exact_synonym: voltage gated ion channel activity involved in regulation of presynaptic membrane potential;   voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential;   voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential;   voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential


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voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna1 potassium voltage-gated channel subfamily A member 1 enables IDA
IMP
NAS		 PMID:8126562 SynGO PMID:8126562 PMID:8126562 PMID:8126562 RGD:13702140, RGD:13702140, RGD:13702140 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 enables EXP
IDA		 PMID:12777451 SynGO PMID:12777451 PMID:12777451 RGD:155230739, RGD:155230739 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400 		JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 enables IEA
ISO		 GO_REF:0000107
(PMID:22615428)		 Ensembl
RGD		 PMID:22615428 GO_REF:0000107 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162 		JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 enables IDA
IMP
NAS		 PMID:10482766 SynGO PMID:10482766 PMID:10482766 PMID:10482766 RGD:9685780, RGD:9685780, RGD:9685780 NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744 		JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 enables IDA
IMP
NAS		 PMID:10482766 SynGO PMID:10482766 PMID:10482766 PMID:10482766 RGD:9685780, RGD:9685780, RGD:9685780 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 enables IDA
IMP
NAS		 PMID:12592408 SynGO PMID:12592408 PMID:12592408 PMID:12592408 RGD:13702380, RGD:13702380, RGD:13702380 NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:195,071,769...195,099,233 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 enables ISO (PMID:25556795) RGD PMID:25556795 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 enables ISO (PMID:18945825) RGD PMID:18945825 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 enables IDA
NAS
IMP		 PMID:7576657 SynGO PMID:7576657 PMID:7576657 PMID:7576657 RGD:155230811, RGD:155230811, RGD:155230811 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 enables ISO (PMID:10956667) RGD PMID:10956667 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 enables ISO (PMID:18945825) RGD PMID:18945825 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 enables NAS
IDA
IMP		 PMID:15111404 SynGO PMID:15111404 PMID:15111404 PMID:15111404 RGD:1581585, RGD:1581585, RGD:1581585 NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278 		JBrowse link
G Kcnq5 potassium voltage-gated channel subfamily Q member 5 enables EXP
IDA		 PMID:21666672 SynGO PMID:21666672 PMID:21666672 RGD:155230700, RGD:155230700 NCBI chr 9:23,830,185...24,395,984
Ensembl chr 9:23,833,087...24,394,704 		JBrowse link
G Rimbp2 RIMS binding protein 2 enables ISO (PMID:29967030) RGD PMID:29967030 NCBI chr12:27,747,615...27,946,256
Ensembl chr12:27,747,980...27,956,763 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 enables IMP
NAS
IDA		 PMID:26187311 SynGO PMID:26187311 PMID:26187311 PMID:26187311 RGD:155230761, RGD:155230761, RGD:155230761 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 enables IEA
ISO		 GO_REF:0000107
(PMID:22150645)		 Ensembl
RGD		 PMID:22150645 GO_REF:0000107 NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 enables IMP
IDA
NAS		 PMID:25615535 SynGO PMID:25615535 PMID:25615535 PMID:25615535 RGD:13702364, RGD:13702364, RGD:13702364 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        monoatomic ion transmembrane transporter activity 770
          monoatomic ion channel activity 457
            voltage-gated monoatomic ion channel activity 186
              voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 17
Path 2
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        passive transmembrane transporter activity 516
          channel activity 516
            gated channel activity 335
              voltage-gated channel activity 190
                voltage-gated monoatomic ion channel activity 186
                  voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 17
paths to the root