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ONTOLOGY REPORT - ANNOTATIONS

Term:presynaptic modulation of chemical synaptic transmission
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Accession:GO:0099171 term browser browse the term
Definition:Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.


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presynaptic modulation of chemical synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 involved_in ISO (PMID:9547227) RGD PMID:9547227 NCBI chr14:86,125,119...86,234,459
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Adora2a adenosine A2a receptor involved_in EXP
IEP
IDA		 PMID:15659214 SynGO PMID:15659214 PMID:15659214 PMID:15659214 RGD:1625642, RGD:1625642, RGD:1625642 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adora2b adenosine A2B receptor involved_in ISO
IEA		 (PMID:25704806)
GO_REF:0000107		 RGD
Ensembl		 PMID:25704806 GO_REF:0000107 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Adora3 adenosine A3 receptor involved_in IDA
EXP		 PMID:8987783 SynGO PMID:8987783 PMID:8987783 RGD:13702310, RGD:13702310 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in EXP
IDA		 PMID:12548707 SynGO PMID:12548707 PMID:12548707 RGD:13702265, RGD:13702265 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO
IEA		 (PMID:11927164)
GO_REF:0000107		 RGD
Ensembl		 PMID:11927164 GO_REF:0000107 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in EXP
IDA		 PMID:17175110 SynGO PMID:17175110 PMID:17175110 RGD:5129150, RGD:5129150 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Apba1 amyloid beta precursor protein binding family A member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12547917), (PMID:17167098)		 Ensembl
RGD		 PMID:12547917 PMID:17167098 GO_REF:0000107 NCBI chr 1:230,790,297...230,995,986
Ensembl chr 1:221,363,778...221,566,553 		JBrowse link
G Apba2 amyloid beta precursor protein binding family A member 2 involved_in ISO
IEA		 (PMID:17167098)
GO_REF:0000107		 RGD
Ensembl		 PMID:17167098 GO_REF:0000107 NCBI chr 1:118,053,270...118,286,858
Ensembl chr 1:118,103,219...118,285,699 		JBrowse link
G Bace1 beta-secretase 1 involved_in ISO
IEA		 (PMID:18753368)
GO_REF:0000107		 RGD
Ensembl		 PMID:18753368 GO_REF:0000107 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Chrd chordin involved_in ISO MGI:2157350 (PMID:17634368) RGD PMID:17634368 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in ISO (PMID:11880500) RGD PMID:11880500 NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit involved_in IDA
EXP		 PMID:12065717 SynGO PMID:12065717 PMID:12065717 RGD:13702272, RGD:13702272 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit involved_in ISO (PMID:12944511) RGD PMID:12944511 NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit involved_in IEA
ISO		 GO_REF:0000107
(PMID:19693710)		 Ensembl
RGD		 PMID:19693710 GO_REF:0000107 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit involved_in IEA
ISO		 GO_REF:0000107
(PMID:12944511)		 Ensembl
RGD		 PMID:12944511 GO_REF:0000107 NCBI chr16:71,400,615...71,407,315
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in EXP
IDA		 PMID:21762741 SynGO PMID:21762741 PMID:21762741 RGD:13702307, RGD:13702307 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit involved_in ISO (PMID:11145999), (PMID:12944511) RGD PMID:11145999 PMID:12944511 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit involved_in ISO
IEA		 (PMID:14657161)
GO_REF:0000107		 RGD
Ensembl		 PMID:14657161 GO_REF:0000107 NCBI chr16:71,411,847...71,454,225
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Cyth1 cytohesin 1 involved_in IDA
IMP		 PMID:9927699 SynGO PMID:9927699 PMID:9927699 RGD:13702340, RGD:13702340 NCBI chr10:103,901,376...103,984,496
Ensembl chr10:103,366,145...103,485,760 		JBrowse link
G Dgki diacylglycerol kinase, iota involved_in IEA
ISO		 GO_REF:0000107
(PMID:21119615)		 Ensembl
RGD		 PMID:21119615 GO_REF:0000107 NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:65,420,108...65,872,733 		JBrowse link
G Drd1 dopamine receptor D1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22586226)		 Ensembl
RGD		 PMID:22586226 GO_REF:0000107 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO
IEA		 (PMID:12223553), (PMID:22586226)
GO_REF:0000107		 RGD
Ensembl		 PMID:12223553 PMID:22586226 GO_REF:0000107 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd4 dopamine receptor D4 involved_in IDA
EXP		 PMID:24155292 SynGO PMID:24155292 PMID:24155292 RGD:13702381, RGD:13702381 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16819522)		 Ensembl
RGD		 PMID:16819522 GO_REF:0000107 NCBI chr19:41,380,125...41,392,078
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26637799)		 Ensembl
RGD		 PMID:26637799 GO_REF:0000107 NCBI chr10:62,840,165...62,854,508
Ensembl chr10:62,342,299...62,356,373 		JBrowse link
G Git2 GIT ArfGAP 2 involved_in ISO (PMID:26637799) RGD PMID:26637799 NCBI chr12:47,490,350...47,531,232
Ensembl chr12:41,829,730...41,871,097 		JBrowse link
G Glra3 glycine receptor, alpha 3 involved_in ISO (PMID:26851771) RGD PMID:26851771 NCBI chr16:39,210,534...39,857,332
Ensembl chr16:34,204,811...34,848,753 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 acts_upstream_of_or_within ISO MGI:95815 (PMID:11985817) RGD PMID:11985817 NCBI chr11:40,655,974...41,056,966
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 acts_upstream_of_or_within ISO
IEA		 MGI:95814 (PMID:11985817)
GO_REF:0000107		 RGD
Ensembl		 PMID:11985817 GO_REF:0000107 NCBI chr20:53,717,564...54,415,283
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A involved_in ISO
IEA		 (PMID:25144876)
GO_REF:0000107		 RGD
Ensembl		 PMID:25144876 GO_REF:0000107 NCBI chr 5:68,802,333...69,001,880
Ensembl chr 5:64,009,980...64,206,085 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in ISO
IEA		 (PMID:31735403)
GO_REF:0000107		 RGD
Ensembl		 PMID:31735403 GO_REF:0000107 NCBI chr 8:116,158,810...116,171,857
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in ISO (PMID:8815915) RGD PMID:8815915 NCBI chr20:5,486,024...5,574,668
Ensembl chr20:5,481,124...5,572,821 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 involved_in ISO (PMID:12065412) RGD PMID:12065412 NCBI chr 4:145,286,714...146,169,099
Ensembl chr 4:143,731,259...144,612,344 		JBrowse link
G Grm8 glutamate metabotropic receptor 8 involved_in EXP
IDA		 PMID:15275822 SynGO PMID:15275822 PMID:15275822 RGD:6484726, RGD:6484726 NCBI chr 4:56,771,247...57,696,951
Ensembl chr 4:55,805,955...56,730,831 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:17989287)		 Ensembl
RGD		 PMID:17989287 GO_REF:0000107 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO (PMID:17928447) RGD PMID:17928447 NCBI chr12:26,769,868...26,904,367
Ensembl chr12:21,133,406...21,267,725 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in IDA
EXP		 PMID:10381597 SynGO PMID:10381597 PMID:10381597 RGD:13702211, RGD:13702211 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in IDA
EXP		 PMID:17067296 SynGO PMID:17067296 PMID:17067296 RGD:13702319, RGD:13702319 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in IDA
EXP		 PMID:12196574 SynGO PMID:12196574 PMID:12196574 RGD:13702246, RGD:13702246 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 involved_in EXP
IDA		 PMID:26779891 SynGO PMID:26779891 PMID:26779891 RGD:13702205, RGD:13702205 NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Lamp5 lysosomal-associated membrane protein family, member 5 involved_in ISO
IEA		 (PMID:27272053)
GO_REF:0000107		 RGD
Ensembl		 PMID:27272053 GO_REF:0000107 NCBI chr 3:123,372,462...123,384,973
Ensembl chr 3:123,372,462...123,384,952 		JBrowse link
G Myo6 myosin VI involved_in ISO (PMID:16819522) RGD PMID:16819522 NCBI chr 8:89,967,351...90,122,219
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Ngfr nerve growth factor receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:31514753)		 Ensembl
RGD		 PMID:31514753 GO_REF:0000107 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nog noggin involved_in IEA
ISO		 GO_REF:0000107
(PMID:17634368)		 Ensembl
RGD		 PMID:17634368 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 involved_in ISO (PMID:18547242) RGD PMID:18547242 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nrn1 neuritin 1 involved_in ISO (PMID:28475719) RGD PMID:28475719 NCBI chr17:28,335,426...28,344,354
Ensembl chr17:28,129,977...28,138,896 		JBrowse link
G Nrxn2 neurexin 2 involved_in ISO (PMID:36608123) RGD PMID:36608123 NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:203,735,753...203,842,297 		JBrowse link
G Nrxn3 neurexin 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26030848)		 Ensembl
RGD		 PMID:26030848 GO_REF:0000107 NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:107,641,780...109,272,044 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in ISO (PMID:31818459) RGD PMID:31818459 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pfn2 profilin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17541406)		 Ensembl
RGD		 PMID:17541406 GO_REF:0000107 NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:142,067,104...142,072,938 		JBrowse link
G Prkca protein kinase C, alpha involved_in ISO (PMID:21658591) RGD PMID:21658591 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcb protein kinase C, beta involved_in ISO (PMID:21658591) RGD PMID:21658591 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkce protein kinase C, epsilon involved_in EXP
IDA		 PMID:26625935 SynGO PMID:26625935 PMID:26625935 RGD:11353024, RGD:11353024 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkcg protein kinase C, gamma involved_in ISO
IEA		 (PMID:24794094)
GO_REF:0000107		 RGD
Ensembl		 PMID:24794094 GO_REF:0000107 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Rgs19 regulator of G-protein signaling 19 involved_in ISO (PMID:16819522) RGD PMID:16819522 NCBI chr 3:189,182,041...189,190,494
Ensembl chr 3:168,804,874...168,810,097 		JBrowse link
G Syt12 synaptotagmin 12 involved_in ISO
IEA		 (PMID:23739973)
GO_REF:0000107		 RGD
Ensembl		 PMID:23739973 GO_REF:0000107 NCBI chr 1:211,158,745...211,189,780
Ensembl chr 1:201,730,371...201,759,609 		JBrowse link
G Tprg1l tumor protein p63 regulated 1-like involved_in IMP
IDA		 PMID:26212709 SynGO PMID:26212709 PMID:26212709 RGD:13792549, RGD:13792549 NCBI chr 5:170,004,577...170,007,784
Ensembl chr 5:164,710,285...164,725,425 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in IEA
ISO		 GO_REF:0000107
(PMID:15543142)		 Ensembl
RGD		 PMID:15543142 GO_REF:0000107 NCBI chr14:81,920,819...81,930,202
Ensembl chr14:77,696,333...77,705,741 		JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 involved_in EXP
IDA		 PMID:24037803 SynGO PMID:24037803 PMID:24037803 RGD:13702177, RGD:13702177 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in IDA
IMP		 PMID:14627637 SynGO PMID:14627637 PMID:14627637 RGD:8554199, RGD:8554199 NCBI chr 7:15,223,613...15,236,754
Ensembl chr 7:14,521,368...14,534,593 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in IEA
ISO		 GO_REF:0000107
(PMID:31679900)		 Ensembl
RGD		 PMID:31679900 GO_REF:0000107 NCBI chr16:18,718,164...18,722,273
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Unc13b unc-13 homolog B involved_in IMP
IEP
IDA		 PMID:31679900 SynGO PMID:31679900 PMID:31679900 PMID:31679900 RGD:155230690, RGD:155230690, RGD:155230690 NCBI chr 5:62,084,809...62,299,884
Ensembl chr 5:57,289,227...57,502,926 		JBrowse link
regulation of protein catabolic process at presynapse, modulating synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxl20 F-box and leucine-rich repeat protein 20 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17803915)		 Ensembl
RGD		 PMID:17803915 GO_REF:0000107 NCBI chr10:83,577,038...83,640,022
Ensembl chr10:83,086,551...83,144,162 		JBrowse link
regulation of translation at presynapse, modulating synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in IDA
IBA
IMP		 PMID:24709664
GO_REF:0000033		 GO_Central PMID:24709664 PMID:24709664 GO_REF:0000033, RGD:11059581, RGD:11059581 NCBI chr  X:152,284,857...152,322,686
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fxr1 FMR1 autosomal homolog 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:118,812,287...118,865,813
Ensembl chr 2:116,884,248...116,937,590 		JBrowse link
G Fxr2 FMR1 autosomal homolog 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,350,577...54,370,964
Ensembl chr10:54,350,131...54,370,964 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    regulation of biological process 13394
      regulation of signaling 3874
        regulation of trans-synaptic signaling 750
          modulation of chemical synaptic transmission 749
            presynaptic modulation of chemical synaptic transmission 67
              induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration 0
              regulation of presynaptic dense core granule exocytosis 4
              regulation of protein catabolic process at presynapse, modulating synaptic transmission 1
              regulation of translation at presynapse, modulating synaptic transmission 3
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        signaling 7862
          cell-cell signaling 1487
            synaptic signaling 1008
              trans-synaptic signaling 964
                anterograde trans-synaptic signaling 956
                  chemical synaptic transmission 956
                    modulation of chemical synaptic transmission 749
                      presynaptic modulation of chemical synaptic transmission 67
                        induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration 0
                        regulation of presynaptic dense core granule exocytosis 4
                        regulation of protein catabolic process at presynapse, modulating synaptic transmission 1
                        regulation of translation at presynapse, modulating synaptic transmission 3
paths to the root