ONTOLOGY REPORT - ANNOTATIONS
Term: postsynaptic specialization, intracellular component
Accession: GO:0099091
browse the term
Definition: A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
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Akap1
A-kinase anchoring protein 1
is_active_in
IDA
PMID:11716788
SynGO
PMID:11716788
RGD:2313126
NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
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Gabarap
GABA type A receptor-associated protein
is_active_in
IDA
PMID:11461150
SynGO
PMID:11461150
RGD:405650362
NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765
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Gphn
gephyrin
is_active_in
IDA ISO
PMID:9714149 (PMID:19955355)
RGD
PMID:19955355 PMID:9714149
RGD:13702207
NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
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Lck
LCK proto-oncogene, Src family tyrosine kinase
is_active_in
IDA IEP
PMID:14529711
SynGO
PMID:14529711 PMID:14529711
RGD:2303716 , RGD:2303716
NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
is_active_in
IDA IEP
PMID:14529711
SynGO
PMID:14529711 PMID:14529711
RGD:2303716 , RGD:2303716
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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Nos1
nitric oxide synthase 1
is_active_in
IDA
PMID:12388603
SynGO
PMID:12388603
RGD:12050093
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Nsf
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
is_active_in
IDA
PMID:11461150
SynGO
PMID:11461150
RGD:405650362
NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
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Sipa1l3
signal-induced proliferation-associated 1 like 3
is_active_in
IDA IEP IMP
PMID:26364583
SynGO
PMID:26364583 PMID:26364583 PMID:26364583
RGD:11074137 , RGD:11074137 , RGD:11074137
NCBI chr 1:84,618,714...84,825,956
Ensembl chr 1:84,618,719...84,703,802
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
is_active_in
IDA IEP
PMID:14529711
SynGO
PMID:14529711 PMID:14529711
RGD:2303716 , RGD:2303716
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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Yes1
YES proto-oncogene 1, Src family tyrosine kinase
is_active_in
IDA IEP
PMID:14529711
SynGO
PMID:14529711 PMID:14529711
RGD:2303716 , RGD:2303716
NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837
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Zdhhc5
zinc finger DHHC-type palmitoyltransferase 5
is_active_in
IDA IMP
PMID:26334723
SynGO
PMID:26334723 PMID:26334723
RGD:11072748 , RGD:11072748
NCBI chr 3:69,772,037...69,800,142
Ensembl chr 3:69,771,890...69,799,921
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Abr
ABR activator of RhoGEF and GTPase
is_active_in
IDA
PMID:20962234
SynGO
PMID:20962234
RGD:13702252
NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505
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Actn2
actinin alpha 2
is_active_in
IDA IEP
PMID:9454847
SynGO
PMID:9454847 PMID:9454847
RGD:13702332 , RGD:13702332
NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
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Akap5
A-kinase anchoring protein 5
is_active_in
IDA IEP IMP
PMID:10939335
SynGO
PMID:10939335 PMID:10939335 PMID:10939335
RGD:2313285 , RGD:2313285 , RGD:2313285
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
is_active_in
IDA
PMID:20575057
SynGO
PMID:20575057
RGD:13702247
NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693
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Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
is_active_in
IMP IEP IDA
PMID:19208802
SynGO
PMID:19208802 PMID:19208802 PMID:19208802
RGD:13432301 , RGD:13432301 , RGD:13432301
NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
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Baiap2
BAR/IMD domain containing adaptor protein 2
is_active_in
IDA IEP
PMID:15673667
SynGO
PMID:15673667 PMID:15673667
RGD:9684988 , RGD:9684988
NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
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Bcr
BCR activator of RhoGEF and GTPase
is_active_in
IDA IEP
PMID:20962234
SynGO
PMID:20962234 PMID:20962234
RGD:13702252 , RGD:13702252
NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016
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Cabp1
calcium binding protein 1
is_active_in
IDA
PMID:11906216
SynGO
PMID:11906216
RGD:13702317
NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
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Cask
calcium/calmodulin dependent serine protein kinase
is_active_in
IDA
PMID:24753440
SynGO
PMID:24753440
RGD:405650264
NCBI chr X:8,899,500...9,243,014
Ensembl chr X:8,899,833...9,238,694
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Cdkl5
cyclin-dependent kinase-like 5
is_active_in
IDA
PMID:23671101
SynGO
PMID:23671101
RGD:12791021
NCBI chr X:33,757,605...33,988,075
Ensembl chr X:33,821,257...33,986,582
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Cfl1
cofilin 1
is_active_in
ISO
(PMID:16388910)
RGD
PMID:16388910
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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Cit
citron rho-interacting serine/threonine kinase
IDA
MMO:0000665|MMO:0000648|MMO:0000683|MMO:0000498
RGD
PMID:9870942
RGD:70684
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
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Cript
CXXC repeat containing interactor of PDZ3 domain
is_active_in
IDA
PMID:11160391
SynGO
PMID:11160391
RGD:155230802
NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399
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Ctnna2
catenin alpha 2
is_active_in
ISO
(PMID:8909549)
RGD
PMID:8909549
NCBI chr 4:109,294,249...110,443,409
Ensembl chr 4:109,293,978...110,443,522
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Ctnnb1
catenin beta 1
located_in is_active_in
IEA ISO
GO_REF:0000107 (PMID:8909549)
Ensembl RGD
PMID:8909549
GO_REF:0000107
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Ctnnd1
catenin delta 1
is_active_in
IDA
PMID:12727444
SynGO
PMID:12727444
RGD:2316208
NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
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Dicer1
dicer 1 ribonuclease III
is_active_in
ISO
(PMID:16092937)
RGD
PMID:16092937
NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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Dlg1
discs large MAGUK scaffold protein 1
is_active_in
IDA
PMID:11029631
SynGO
PMID:11029631
RGD:13702352
NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
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Dlg3
discs large MAGUK scaffold protein 3
is_active_in
IDA
PMID:20357126
SynGO
PMID:20357126
RGD:13702192
NCBI chr X:65,859,653...65,911,887
Ensembl chr X:65,860,172...65,910,322
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Dlgap1
DLG associated protein 1
is_active_in
IDA
PMID:25775468
SynGO
PMID:25775468
RGD:12050094
NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817
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Dlgap2
DLG associated protein 2
is_active_in
ISO
(PMID:19640847)
RGD
PMID:19640847
NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407
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Dnm2
dynamin 2
is_active_in
IMP IEP IDA
PMID:11583995
SynGO
PMID:11583995 PMID:11583995 PMID:11583995
RGD:628513 , RGD:628513 , RGD:628513
NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
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Exoc4
exocyst complex component 4
is_active_in
IDA
PMID:12738960
SynGO
PMID:12738960
RGD:8554028
NCBI chr 4:61,807,706...62,584,316
Ensembl chr 4:61,807,761...62,585,723
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Fabp5
fatty acid binding protein 5
is_active_in
ISO
(PMID:29531087)
RGD
PMID:29531087
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
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Fam81a
family with sequence similarity 81, member A
is_active_in
IDA
PMID:30735723
SynGO
PMID:30735723
RGD:155230695
NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875
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Fyn
FYN proto-oncogene, Src family tyrosine kinase
is_active_in
IDA IEP
PMID:27457929
SynGO
PMID:27457929 PMID:27457929
RGD:11555024 , RGD:11555024
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
is_active_in
IDA
PMID:9371836
SynGO
PMID:9371836
RGD:13702148
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Gria1
glutamate ionotropic receptor AMPA type subunit 1
IDA
MMO:0000679
RGD
PMID:26088419
RGD:11096590
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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Grid2ip
Grid2 interacting protein
is_active_in
ISO
(PMID:11826110)
RGD
PMID:11826110
NCBI chr12:11,166,567...11,203,765
Ensembl chr12:11,167,874...11,203,676
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
IDA
MMO:0000679
RGD
PMID:26088419
RGD:11096590
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
IDA
MMO:0000679
RGD
PMID:26088419
RGD:11096590
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Grip2
glutamate receptor interacting protein 2
is_active_in
IDA IEP
PMID:9768844
SynGO
PMID:9768844 PMID:9768844
RGD:632960 , RGD:632960
NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268
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Ina
internexin neuronal intermediate filament protein, alpha
is_active_in
IDA IEP
PMID:9310396
SynGO
PMID:9310396 PMID:9310396
RGD:13702147 , RGD:13702147
NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
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Iqsec1
IQ motif and Sec7 domain ArfGEF 1
is_active_in
ISO
(PMID:22886754)
RGD
PMID:22886754
NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
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Iqsec2
IQ motif and Sec7 domain ArfGEF 2
is_active_in
ISO
(PMID:18164504)
RGD
PMID:18164504
NCBI chr X:21,254,799...21,337,179
Ensembl chr X:21,254,914...21,336,584
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Lin7b
lin-7 homolog B, crumbs cell polarity complex component
is_active_in
IDA
PMID:24753440
SynGO
PMID:24753440
RGD:405650264
NCBI chr 1:95,846,888...95,849,628
Ensembl chr 1:95,846,243...95,849,977
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Mmp9
matrix metallopeptidase 9
is_active_in
IDA
PMID:18332222
SynGO
PMID:18332222
RGD:405650358
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Nos1
nitric oxide synthase 1
is_active_in
IDA
PMID:12388603
SynGO
PMID:12388603
RGD:12050093
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
is_active_in
IDA
PMID:21179518
SynGO
PMID:21179518
RGD:4892203
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Nr3c2
nuclear receptor subfamily 3, group C, member 2
is_active_in
IDA
PMID:21179518
SynGO
PMID:21179518
RGD:4892203
NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
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Prr7
proline rich 7 (synaptic)
is_active_in
IDA IBA IEP IMP
PMID:15629447 GO_REF:0000033
GO_Central
PMID:15629447 PMID:15629447 PMID:15629447
GO_REF:0000033, RGD:1579799 , RGD:1579799 , RGD:1579799
NCBI chr17:9,164,375...9,173,669
Ensembl chr17:9,165,269...9,172,536
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Psd
pleckstrin and Sec7 domain containing
located_in is_active_in
IEA ISO
GO_REF:0000107 (PMID:24261326)
Ensembl RGD
PMID:24261326
GO_REF:0000107
NCBI chr 1:245,173,279...245,188,681
Ensembl chr 1:245,173,279...245,189,356
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Ptk2b
protein tyrosine kinase 2 beta
is_active_in
IMP ISO IDA
PMID:20071509 (PMID:28555636)
RGD
PMID:28555636 PMID:20071509 PMID:20071509
RGD:155230731 , RGD:155230731
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
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Sh3gl1
SH3 domain containing GRB2 like 1, endophilin A2
is_active_in
IDA
PMID:17088211
SynGO
PMID:17088211
RGD:10047209
NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
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Sh3gl3
SH3 domain containing GRB2 like 3, endophilin A3
is_active_in
IMP IDA
PMID:17088211
SynGO
PMID:17088211 PMID:17088211
RGD:10047209 , RGD:10047209
NCBI chr 1:136,124,500...136,255,669
Ensembl chr 1:136,124,499...136,255,584
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Shank3
SH3 and multiple ankyrin repeat domains 3
is_active_in
IDA IEP
PMID:15894489
SynGO
PMID:15894489 PMID:15894489
RGD:12050114 , RGD:12050114
NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
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Sipa1l2
signal-induced proliferation-associated 1 like 2
is_active_in
IDA IMP
PMID:17961154
SynGO
PMID:17961154 PMID:17961154
RGD:405650284 , RGD:405650284
NCBI chr19:53,389,792...53,540,466
Ensembl chr19:53,389,805...53,540,428
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Slc30a1
solute carrier family 30 member 1
IDA
MMO:0000679
RGD
PMID:25319628
RGD:11057402
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
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Snx1
sorting nexin 1
is_active_in located_in
ISO
(PMID:24261326)
RGD
PMID:24261326
NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360
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Syngap1
synaptic Ras GTPase activating protein 1
is_active_in
IDA
PMID:21736925
SynGO
PMID:21736925
RGD:7241542
NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672
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Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
is_active_in
IDA IMP
PMID:21068316
SynGO
PMID:21068316 PMID:21068316
RGD:11353167 , RGD:11353167
NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627
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Tanc2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
is_active_in
IDA IMP
PMID:21068316
SynGO
PMID:21068316 PMID:21068316
RGD:11353167 , RGD:11353167
NCBI chr10:90,553,124...90,873,477
Ensembl chr10:90,553,002...90,868,756
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Tnik
TRAF2 and NCK interacting kinase
is_active_in
IDA
PMID:20838393
SynGO
PMID:20838393
RGD:13702418
NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750
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Wwc1
WW and C2 domain containing 1
is_active_in
IDA IEP
PMID:18672031
SynGO
PMID:18672031 PMID:18672031
RGD:405650397 , RGD:405650397
NCBI chr10:20,300,735...20,454,393
Ensembl chr10:20,300,833...20,454,497
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